Synactix Pharmaceutical Inc. Anureet (sandy) Pabla Student Innovation Fellow, 2014 – 2015 Tech Launch Arizona Introduction u  u  B.S. Molecular and Cellular Biology u  Minor in Business Administration u  Class of 2015 (Graduating in two weeks!) What sparked my interest in commercialization u  Summer job as a Pharmacy Technician u  How did a drug end up on the shelf? u  Theranos – the lab test, reinvented Synactix Pharmaceuticals Inc. u  Founded June 2014 u  University of Arizona, department of pharmacology and toxicology u  Drug Discovery, focus on the Medically underserved u  Dr. Hong-yu Li and Dr. Brendan Frett u  RET inhibitor which aids in the fight against cancer u  Medullary Thyroid Cancer u  4% out of all thyroid cancers (600,000) Technology and Research u  Small Molecule Benefits u  Targets both RET and VEGFR-2 u  Active on both sites u  Long shelf life u  Very specific – fragment drug discovery u  Water soluble Comparable Drugs u  Same target, RET, VEGFR-2, MTC u  Clinical Trials for other cancers u  Toxic/ FDA approval Risks Next Steps u  Start marketing the company more u  Develop the face of Synactix u  Keep options open u  Create goals and missions to help narrow in on what to do The Fellows Experience u  Great real world experience in how processes like commercialization work u  Exposure to the fluidity of a startup u  Great introduction to the pharmaceutical industry u  Influential to my future career and plans after graduation u  Met and worked with wonderful people and other Innovation Fellows!