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CURRICULUM VITAE
September 2013
JOHN L. GRIFFITH, PhD
Associate Dean for Research
Bouvé College of Health Sciences
Northeastern University
Office of Research, Bouvé College of Health Sciences
110 Behrakis Health Science Center
Northeastern University
360 Huntington Avenue
Boston, MA. 02115
Telephone: (617) 373-7516
EDUCATION
Boston University, Boston, MA
Tufts University, Medford, MA
Claremont Men's College, Claremont, CA.
Ph.D.
M.S.
B.A.
Mathematics 1994
Mathematics 1982
1976
ACADEMIC APPOINTMENTS
Bouvé College of Health Sciences, Northeastern University
2012 - Present
Professor, Departments of Health Sciences and Counseling and Applied
Educational Psychology
Tufts Sackler Graduate School of Biomedical Sciences
2002 - 2012
Associate Professor of Medicine
Tufts University School of Medicine
2102 - Present
Adjunct Associate Professor of Medicine
1999 - 2012
Associate Professor of Medicine
1996 - 2012
Assistant Professor of Family Medicine and Community Health
1993 - 1999
Assistant Professor of Medicine
Tufts University School of Veterinary Medicine
1995
Quantitative Course Director, Animals and Public Policy
Boston University
1982-1990
Lecturer, Department of Mathematics
Tufts University
1980-1982
Lecturer, Department of Mathematics
Curriculum Vitae - John L Griffith
Page 2
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PROFESSIONAL ACTIVITIES
Journal Reviewer
Clinical Infectious Disease, Statistical Editor 2003-2006
American Heart Journal
Circulation
Journal of Clinical Pharmacology
Journal of Women’s Health
Medical Decision Making
Statistics in Medicine
Trials
Selected Hospital and University Appointments
Associate Dean for Research
Bouvé College of Health Sciences, Northeastern University, 2012 to present
Biostatistics Core Tufts MC Cancer Center, Director
Tufts Medical Center, 2009 to 2012
Human Institutional Review Board
Tufts University / Tufts Medical Center, 2000 to 2011
Special and Scientific Staff
Tufts Medical Center, 2000 to 2012
Center for Cardiovascular Health Services Research, Senior Statistician
Tufts Medical Center, 1988 to 2012
Tufts Clinical and Translational Science Institute, Associate Director
Tufts University School of Medicine, 2008 to 2011
The Research Design Center (formerly the Design and Data Resource Center), Director
Tufts Medical Center, 2006 to 2008
Tufts Clinical and Translational Science Institute, 2008 to 2011
Clinical Research Portal, co-Director
Tufts Clinical and Translational Science Institute, 2008 to 2011
Clinical Research Scientific Review Committee
Tufts Medical Center, 2003 to 2008
General Clinical Research Center, Statistical Director
Tufts Medical Center, 2001 to 2006
Biostatistics Research Center, Director
Tufts Medical Center, 1989 to 2006
Curriculum Vitae - John L Griffith
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Selected Faculty Committee Memberships
2013
Northeastern University
Research Computing Advisory Committee
2013
Bouvé College of Health Sciences
Ad Hoc Committee on IS Infrastructure, Chair
2011 - 2012
Tufts Sackler School of Biomedical Sciences, CTS program
Admissions Committee
2011 - 2012
Tufts Sackler School of Biomedical Sciences, CTS program
PhD Qualifying Exam Committee
1999 - 2012
Tufts Sackler School of Biomedical Sciences, CTS Program
Faculty Advisory Committee
1999 - 2012
Tufts Medical Center, Fellowship in Clinical Care Research
Faculty Advisory Committee
2011
Faculty Recruitment Committee, Department of Health Sciences
Northeastern University
2009 - 2010
Tufts University
Research IT Steering Committee
2004 - 2010
Institute for Clinical Research and Health Policy Studies
Infrastructure Committee, Chair
2003 - 2008
Tufts Medical Center
Research Information Services Committee, Chair
1999 - 2001
Tufts University Sackler School of Biomedical Sciences, Clinical Research Program
PhD Qualifying Exam Committee
1995 - 2001
New England Medical Center, Fellowship in Clinical Care Research
Admissions Committee
Scientific Review Committees
Scientific Review and Evaluation Board for Health Services Research.
Department of Veterans Affairs. June 2002 – June 2006.
Medical Treatment Effectiveness Research: Port II Special Emphasis Panel.
Agency for Health Care Policy and Research (AHCPR). March 1995 & June 1995.
Medical Treatment Effectiveness Research: Port II Special Emphasis Panel.
Agency for Health Care Policy and Research (AHCPR). March 1994
Curriculum Vitae - John L Griffith
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Selected Workshops and Presentations (since 2011)
““Modeling using SAS”
Boston Public Health Commission, May 2013
“Research at the Bouvé College of Health Sciences”
Bouvé College Honors Program, November 2012
“Exploratory Data Analysis”
Boston Public Health Commission, April 2012
“Analysis of Complex Survey Data in SAS”
Boston Public Health Commission, January 2012
“Why Studies Fail: Bias & Confounding”
Lahey Clinic, November 2011
“How Many Subjects do I Need for My Study?”
Tufts Medical Center (Infectious Disease), August 2011
“Interactions and Confounding”
Boston Public Health Commission, October 2011
“Sample Size and Non-Inferiority Testing”
Clinical and Translational Science Program, October 2011
“Pitfalls in Statistical Analyses”
St. Elizabeth’s Medical Center (Psychiatry), August 2011
“Exploratory Data Analysis”
St. Elizabeth’s Medical Center (Psychiatry), August 2011
“Translational Research”
New England Baptist Hospital, Keynote address Research Day, June 2011
“Statistical review & Evaluating Medical Journals”
Tufts Medical Center (Radiation Oncology), June 2011
“Analyzing Complex Survey Data in SAS”
Boston Public Health Commission, June 2011
“Observational Studies”
Cummings School of Veterinary Medicine, June 2011
“Pitfalls in Statistical Analyses”
Tufts Medical Center (Radiation Oncology), June 2011
“Steps of an analysis”
Lahey Clinic, April 2011
“Regression Analyses”
St. Elizabeth’s Medical Center, April 2011
“Pitfalls in Statistical Analysis”
St. Elizabeth’s Medical Center, March 2011
“Adaptive Randomization”
Tufts Medical Center (Biostatistics Research Center), March 2011
Curriculum Vitae - John L Griffith
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“Exploratory Data Analysis”
Lahey Clinic, February 2011
“Measures of Association”
Tufts Medical Center, 2011
Workshops at National Meetings
“Testing Logistic Regression Predictive Instruments: Different Measures for Different Applications”. HP
Selker, JL Griffith, RB D’Agostino. 12th Annual Meeting of the Society of General Internal Medicine,
Washington DC. May 4, 1989.
“Logistic Regression Predictive Instruments: Different Measures for Different Applications”. HP Selker,
JL Griffith, RB D’Agostino. 13th Annual Meeting of the Society of General Internal Medicine,
Washington DC. May 3, 1990.
“Techniques for Assessing the Performance of Logistic Regression Clinical Predictive Instruments”. HP
Selker, JL Griffith, RB D’Agostino. 15th Annual Meeting of the Society of General Internal Medicine,
Washington DC. April 30, 1992.
“Combining Data from Multiple Clinical Studies for Medical Effectiveness and Clinical Research”. HP
Selker, JL Griffith, JR Beshansky, JD Scott. 16th Annual Meeting of the Society of General Internal
Medicine, Washington DC. April 29, 1993.
“Comparison of Using Logistic Regression, Classification Trees, and Neural Networks for Predicting a
Medical Outcome”. JL Griffith, HP Selker. 17th Annual Meeting of the Society of General Internal
Medicine, Washington DC. April 28, 1994.
“Advanced Construction of Predictive Models for Medical Outcomes”. JL Griffith, HP Selker, C
Schmid. 19th Annual Meeting of the Society of General Internal Medicine, Washington DC. May 2,
1996.
“Advanced Construction of Predictive Models for Medical Outcomes”. JL Griffith, HP Selker, C Schmid.
20th Annual Meeting of the Society of General Internal Medicine, Washington DC. May 3, 1997.
“Advanced Construction of Predictive Models for Medical Outcomes”. HP Selker, JL Griffith. 21st
Annual Meeting of the Society of General Internal Medicine, Chicago, April 23, 1998.
International Workshops
Statistical Coordinator, "ADDR Workshop on Multivariable Analysis". The Applied Diarrheal Disease
Research Project (ADDR). Funded by U.S. Agency for International Development. Islamabad,
Pakistan. May 11-18, 1994.
Curriculum Vitae - John L Griffith
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Course Responsibilities (Since 2009)
Fall
2013
Experimental Design and Biostatistics (PHSC 6214), co-instructor
Northeastern University Bouvé College School of Pharmacy
Spring
2013
Research Methodology and Biostatistics (PHMD 3450), co-instructor
Northeastern University Bouvé College School of Pharmacy
Spring
2012
Fall
2011
Fall
2011
Biostatistics II (CRES 535)
Sackler Graduate School of Biomedical Sciences
Statistical Methods for Epidemiology (Nutr 318)
Tufts Friedman School of Nutrition Science and Policy
Predictive Models for Health Outcomes (CRES 510)
Sackler Graduate School of Biomedical Sciences
Introduction to Clinical Care Research (CRES 525)
Sackler Graduate School of Biomedical Sciences
Summer 2011
Fall
2010
Summer 2010
Summer 2010
Fall
2009
Fall
2009
Summer 2009
Summer 2009
Statistical Methods for Epidemiology (Nutr 318)
Tufts Friedman School of Nutrition Science and Policy
Introduction to Clinical Care Research (CRES 525)
Sackler Graduate School of Biomedical Sciences
Biostatistics \ Quantitative Reasoning (CRES 504)
Sackler Graduate School of Biomedical Science
Statistical Methods for Epidemiology (Nutr 318)
Tufts Friedman School of Nutrition Science and Policy
Predictive Models for Health Outcomes (CRES 510)
Sackler Graduate School of Biomedical Sciences
Introduction to Clinical Care Research (CRES 525)
Sackler Graduate School of Biomedical Sciences
Biostatistics \ Quantitative Reasoning (CRES 504)
Sackler Graduate School of Biomedical Science
Doctoral Thesis Committees
Azizah Jamal-Allial, PhD, Health Sciences, Northeastern University Bouvé College, 2013
“Serum 25(OH)D Concentrations & Cardiovascular Disease Risk Associations Among Older
Puerto Ricans”
Navdeep Tangri, PhD Clinical & Translational Science, Sackler School of Biomedical Sciences, 2012
“Risk Prediction for Patients with Chronic Kidney Disease”
Jennifer Layne, PhD Tufts University Friedman School of Nutrition Science and Policy, 2007
“Dissemination of and adherence to a community-based strength training program for older adults”
David Mkaya Mwamburi, PhD Clinical Research, Tufts Sackler School of Biomedical Sciences, 2006
“Cost-Effectiveness of MDOT strategies for HAART and geographic translation modeling across
disparate populations: from Providence to Cape Town”
Adam Parker, PhD Statistics, Boston University, 1999
“The performance of classification trees with data missing completely at random”
Curriculum Vitae - John L Griffith
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PUBLICATIONS
1.
Pozen MW, D'Agostino RB, Selker HP, Griffith JL. Tables for using a predictive instrument for
acute ischemic heart disease. Distributed to physicians.
2.
Selker HP, Griffith JL, Dorey FJ, D'Agostino RB. How do physicians adapt when the coronary
care unit is full? A prospective multicenter clinical trial. JAMA, 257:1181-85, 1987.
3.
Griffith JL, Selker HP, Beshansky JR, MacLeod BG. Cardiac Severity System Software.
Prepared with support of the Robert Wood Johnson Foundation, 1989.
4.
Selker HP, Griffith JL, D'Agostino RB. A tool for judging coronary care unit admission
appropriateness valid for both real-time and retrospective use: A time-insensitive predictive
instrument (TIPI) for acute cardiac ischemia: A multicenter study. Med Care, 29:610-627, 1991.
5.
Selker HP, Griffith JL, D'Agostino RB. A time-insensitive predictive instrument for acute
myocardial infarction mortality: A multicenter study. Med Care, 29:1196-1211, 1991.
6.
Snydman DR, Werner BG, Tilney NL, Kirkman RL, Milford EL, Cho SI, Bush HL, Levey AS,
Strom TB, Carpenter CB, Berardi VP, Levey RH, Harmon WE, Zimmerman CE, Katz A, HeinzeLacey B, Shapiro ME, Steinman T, LoGerfo F, Idelson B, McIver J, Leszczynski J, Griffith JL,
Grady GF. Final analysis of primary cytomegalovirus disease prevention in renal transplant
recipients with a cytomegalovirus-immune globulin: comparison of the randomized and open-label
trials. Transplantation Proceedings, 23:1357-60, 1991.
7.
Georgeson S, Linzer M, Griffith JL, Weld L, Selker HP. Acute cardiac ischemia in patients with
syncope: Importance of the initial electrocardiogram. J Gen Int Med, 7:379-386, 1992.
8.
Selker HP, Griffith JL, Beshansky JR, Califf RM, D'Agostino RB, Laks MM, Lee KL Maynard C,
Wagner GS, Weaver WD. The Thrombolytic Predictive Instrument (TPI) Project: Combining
clinical study databases to take medical effectiveness research to the streets. AHCPR DHHS,
USA,9-31, 1992.
9.
Long WJ, Griffith JL, Selker HP, D'Agostino RB. A comparison of logistic regression to decision
tree induction in a medical domain. Comput Biomed Res, 26:74-97, 1993.
10.
Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rubin RH, Dienstag JL, Rohrer RH,
Freeman R, Jenkins R, Lewis D, Hammer S, O'Rourke E, Grady G, Fawaz K, Kaplan MM,
Hoffman MA, Katz AT, Doran M. Cytomegalovirus immune prophylaxis in liver transplantation: a
randomized, double-blind, placebo-controlled trial. Ann Intern Med, 119:984-991, 1993.
11.
George MJ, Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rohrer RH, Freeman R,
Jenkins R, Lewis WD. Use of ganciclovir plus cytomegalovirus immune globulin to treat CMV
pneumonia in orthotopic liver transplant recipients. Trans Proc, 25:22-24, 1993.
12.
Griffith JL. Maximum likelihood estimates for feed forward multi-layer neural networks. PhD
dissertation, Boston University, 1994.
13.
Larsen GC, Griffith JL, Beshansky JR, D'Agostino RB, Selker HP. Electrocardiographic left
ventricular hypertrophy in patients with suspected acute cardiac ischemia: its influence on
diagnosis, triage and short-term prognosis. A multicenter study. J Gen Intern Med, 9:666-673,
1994. [PMID: 7876948]
14.
Sarasin FP, Reymond JM, Griffith JL, Beshansky JR, Schifferli JA, Unger PF, Scherrer JR, Selker
HP. Impact of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) on the
speed of triage decision making for emergency department patients presenting with chest pain: a
controlled clinical trial. J Gen Intern Med, 9;187-194, 1994.
Curriculum Vitae - John L Griffith
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15.
Selker HP, Beshansky JR, Schmid CS, Griffith JL, Longstreth WT, O'Connor CM, Caplan LR,
Massey EW, D'Agostino RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD, Califf RM.
Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage:
thrombolytic predictive instrument (TPI) project results. Circulation, 90:1657-1661, 1994.
16.
Selker HP, Griffith JL, D'Agostino RB. A time-insensitive predictive instrument for acute mortality
due to congestive heart failure: development, testing, and use for comparing hospitals. A multicenter study. Med Care, 32:1040-1052, 1994.
17.
Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rohrer RH, Freeman R, Jenkins R. Lewis
WD O'Rourke E, and the Boston Center for Liver Transplantation CMVIG-Study Group. A further
analysis of the use of cytomegalovirus immune globulin in orthoptic liver transplant patients at risk
for primary infection. Trans Proc, 26:23-27, 1994.
18.
Udelson JE, Coleman PS, Metherall J, Pandian NG, Gomez AR, Griffith JL, Shea NL, Oates E,
Konstam MA. Predicting recovery of severe regional ventricular dysfunction: comparison of
resting scintigraphy with thallium201 and technetium99-sestamibi. Circulation, 89:2552-2561,
1994.
19.
Chuttani K, Metherall J, Griffith J, Oates E, Konstam MA, Pauker SG, Salem DM, Udelson JE.
Enhanced hepatic uptake of thallium-210 in patients with severe narrowing of the right coronary
artery. AM J Cardiol, 76:1020-1024, 1995.
20.
Maynard C, Selker HP, Beshansky JR, Griffith JL, Schmid CH, Califf RM, D'Agostino RB, Laks
MM, Lee KL, Wagner GS, Weaver WD. The exclusion of women from clinical trials of
thrombolytic therapy: implications for developing the thrombolytic predictive instrument. Med
Decis Making,15:38-43, 1995.
21.
Selker, HP, Griffith JL, Patil S, Long WL, D'Agostino RB. A comparison of the performance of
mathematical predictive methods for medical diagnosis: the emergency department presentation
of acute cardiac ischemia. J of Investig Med; 43:468-476, 1995.
22.
Snydman DR, Werner BG, Meissner HC, Cheeseman SH, Schwab J, Bednarek F, Kennedy JL,
Herschel M, Magno A, Levin MJ, Valaes T, Berkman E, McIver J, Leszczynski J, Griffith JL,
Grady GF. Use of cytomegalovirus immune globulin in multiply transfused premature neonates.
Pediatr Infect Dis J;14:34-40, 1995.
23.
Falagas ME, Snydman DR, George M, Werner B, Ruthazer R, Griffith J, Werner BG, Freeman R,
Rohrer R, Freeman R, and the Boston Center for Liver Transplantation CMVIG Study Group.
Incidence and predictors of cytomegalovirus pneumonia in orthotopic liver transplant recipients.
Transplantation; 61; 1716-1720, 1996.
24.
Falagas ME, Snydman DR, Ruthazer R, Griffith J, and the Boston Center for Liver
Transplantation CMVIG study group. Primary cytomegalovirus infection in liver transplant
recipients: comparison of infections transmitted via donor organs and via transfusions. Clinical
Infectious Diseases; 23; 292-297, 1996.
25.
Falagas ME, Snydman DR, Griffith J, Werner BG, and the Boston Center for Liver
Transplantation CMVIG study group. Exposure to cytomegalovirus from the donated organ is a
risk factor for bacteremia in orthotopic liver transplant recipients. Clin Infect Diseases; 23;468-74,
1996. [PMID: 8879766]
26.
Katz DA, Beshansky JR, Griffith JL, Selker HP. The need to include empiric clinical data in
formulating medical practice guidelines. JAMA, 276;1568-74, 1996. [PMID: 8918854]
Curriculum Vitae - John L Griffith
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27.
Kimmelstiel CD, Perrone R, Kilcoyne L, Souhrada J, Udleson J, Smith J, de Bold A, Griffith JL,
Konstam MA. Effects of renal neutral endopeptidase inhibition on sodium excretion, renal
hemodynamics and neurohormonal activation in patients with congestive heart failure.
Cardiology, 87:46-53, 1996.
28.
Maynard C, Beshansky JR, Griffith JL, Selker HP. The influence of sex on the use of cardiac
procedures in patients presenting to the emergency department: A prospective multicenter study.
Circulation, 94:93-98, 1996.
29.
Midgette AS, Griffith JL, Califf RM, Laks MM, Dietz SB, Beshansky JR, Selker HP. Prediction of
the infarct-related artery in acute myocardial infarction by a scoring system using summary STsegment and T-wave changes. Am J Cardiol, 78:389-395, 1996. [PMID: 8752181]
30.
Coronado BE, Griffith JL, Beshansky JR, Selker HP. Hospital mortality in women and men
presenting to the emergency department with acute cardiac ischemia: A prospective multicenter
study. J Am Coll Cardiol, 29:1490-1496, 1997.
31.
D’Agostino RB Sr., Griffith JL, Schmid CH and Terrin NT (1997). Measures for evaluating model
performance. Proceedings of the Biometrics Section, American Statistical Association, 1997.
32.
Falagas ME, Snydman DR, Griffith J, Ruthazer R, Werner BG, and the Boston Center for Liver
Transplantation CMVIG study group. Effect of Cytomegalovirus infection on first-year mortality
rates among orthotopic liver transplant recipients. Ann Intern Med, 126:275-279, 1997.
33.
Falagas ME, Barefoot L, Griffith J, Ruthazer R, Snydman DR. Risk factors leading to clinical
failure in patients with intra-abdominal or skin/soft tissue infections. Eur. J. Clin. Microbiol. Infect.
Dis, 15:913-921, 1997.
34.
Falagas ME, Snydman DR, Ruthazer R, Werner BG, Griffith JL and the Boston Center for Liver
Transplantation CMVIG Study Group. Surveillance cultures of blood, urine, and throat specimens
are not valuable for predicting cytomegalovirus disease in liver transplant recipients. Clin Infect
Dis, 24:824-829, 1997.
35.
Falagas ME, Arbo M, Ruthazer R, Griffith J, Werner BG, Rohrer R, Freeman R, Lewis WD,
Snydman DR. Cytomegalovirus disease is associated with increased cost and hospital length of
stay among orthotopic liver transplant recipients. Transplantation 63: 1595-1601, 1997.
36.
Falagas ME, Snydman DR, Griffith JL, Werner BG, Freemen R, and the Boston Center for Liver
Transplantation CMVIG Study Group. Clinical and epidemiological predictors of recurrent
cytomegalovirus disease in orthotopic liver transplant patients. Clin Infec Dis 25:314-317, 1997.
37.
Falagas ME, Snydman DR, Griffith JL, Ruthazer R, Werner BG, Freemen R, Rohrer R and the
Boston Center for Liver Transplantation CMVIG Study Group. Cytomegalovirus immune globulin
(CMVIG) is associated with increased survival after orthotopic liver transplantation. Clin Trans
11:432-437, 1997.
38.
George M, Snydman DR, Werner BG, Griffith JL, Falages ME, Doughery NN, Rubin R, and the
Boston Center for Liver Transplantation CMVIG Study Group. The independent role of
cytomegalovirus as a risk factor for invasive fungal disease in orthotopic liver transplant
recipients. Amer J Med 103:106-113, 1997.
39.
Griffith JL, Schmid CH, Terrin N and D’Agostino RB Sr. Impact of sample size and outcome
prevalence on the predictive performance of logistic regression, classification trees and neural
networks. Proceedings of the Biometrics Section, American Statistical Association, 1997.
Curriculum Vitae - John L Griffith
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40.
Hayes DL, Wang PJ, Reynolds DW, Estes M, Griffith JL, Steffens RA, Carol GL, Findlay GK,
Johnson CM. Pacemaker interference form hand-held wireless telephones: results of a multicenter study. NEJM 336:1473-1479, 1997.
41.
Link MS, Costeas X, Griffith JL, Colburn CC, Estes M, Wang PJ. High incidence of appropriate
implantable cardioverter defibrillator therapy in patients with syncope of unknown etiology. J Am
Coll Cardiol, 29:370-375, 1997.
42.
Maynard C, Beshansky JR, Griffith JL, Selker HP. Causes of chest pain and symptoms
suggestive of acute cardiac ischemia in African American patients presenting to the emergency
department: a multicenter study. JNMA, 89:665-671, 1997.
43.
Schmid CH, D’Agostino RB, Griffith JL, Beshansky JR, Selker HP. A logistic regression model
when some events precede treatment: the effect of thrombolytic therapy for acute myocardial
infarction on the risk of cardiac arrest. J Clin Epidemiol, 50:1219-1229, 1997.
44.
Schmid CH, Griffith JL, Terrin NT, and D’Agostino RB Sr. Synthesising the treatment of missing
data in logistic regression, classification trees and neural networks. Proceedings of the
Biometrics Section, American Statistical Association, 1997.
45.
Sege B, Perry C, Stigol L, Cohen L, Cohn L, Griffith J, Cohen M, Spivak H. Short-term
effectiveness of anticipatory guidance to reduce early childhood risks for subsequent violence.
Arch Pediatr Adolesc Med, 151:392-397, 1997.
46.
Selker HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D’Agostino RB, Laks MM, Lee KL,
Maynard C, Selvester RH, Wagner GS, Weaver WD. Patient-specific predictions of outcomes in
myocardial infarction for real-time emergency use: a thrombolytic predictive instrument. Ann
Intern Med, 127: 538-556, 1997
47.
Terrin N, Griffith JL, Schmid CH and D’Agostino RB Sr. The impact of outliers and distortions on
the predictive performance of logistic regression, classification trees and neural networks.
Proceedings of the Biometrics Section, American Statistical Association, 1997.
48.
Zucker DR, Griffith JL, Beshansky JR, Selker HP. Presentations of acute myocardial infarction in
men and women. JGIM, 12:79-87, 1997.
49.
Faith MS, Manibay E, Kravitz M, Griffith J, Allison DB. Relative body weight and self-esteem
among African Americans in four nationally representative samples. Obesity Research, 6: 430437, 1998. [PMID: 9845233]
50.
Falagas ME, Walker AM, Jick H, Ruthazer R, Griffith JL, Snydman DR. Late incidence of cancer
after metronisaxole use: a matched metronisazole use/nonuser study. Clin Inf. Dis, 26:383-8,
1998. [PMID: 9502459]
51.
Falagas ME, Paya C, Ruthazer R, Badley A, Patel R, Wiesner R, Griffith J, Freeman R, Rohrer R,
Werner BG, Snydman DR. Significance of Cytomegalovirus for Long-Term Survival after
Orthotopic Liver Transplantation: A Prospective Derivation and Validation Cohort Analysis.
Transplantation, 66: 1020-1028, 1998. [PMID: 9808486]
52.
Kulig J, Valentine J, Griffith JL, Ruthazer R. Predictive model of weapon-carrying among urban
high school students. J Adol Health, 22:312-319, 1998. [PMID: 9561463]
53.
Picken HA, Zucker DR, Griffith JL, Beshansky JR, Selker HP. Insurance type and the
transportation to emergency departments for patients with acute cardiac ischemia: the ACI-TIPI
trial insurance study. Amer J Managed Care, 4:821-827, 1998. [PMID: 10181068]
Curriculum Vitae - John L Griffith
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54.
Pope JH, Ruthazer R, Beshansky JR, Griffith, JL, Selker HP. Clinical features of emergency
department patients presenting with symptoms suggestive of acute cardiac ischemia: A
multicenter study. Journal of Thrombosis and Thrombolysis, 6:63-74, 1998. [PMID: 10751787]
55.
Selker HP, Beshansky JR, Griffith JL, Aufderheide TP, Ballin DX, Bernard SA, Crespo SG,
Feldman J, Fish SS, Gibler WB, Kiez DA, McNutt RA, Moulton AW, Ornato JP, Podried PJ,
Salem DN, Sayre MR, Woolard RH. The use of the Acute Cardiac Ischemic Time-Insensitive
Predictive Instrument (ACI-TIPI) to assist emergency department triage of patients with chest
pain or other symptoms suggestive of acute cardiac ischemia: a multicenter controlled clinical
trial. Ann Intern Med, 129:845-855, 1998. [PMID: 9867725]
56.
Valentine J, Griffith JL, Ruthazer R, Gottlief B, Keel S. Strengthening causal inference in
adolescent drug prevention studies: methods and findings from a controlled study of the urban
youth connection program. Drugs & Society, 12:127-145, 1998.
57.
Valentine J, Gottlieb B, Keel S, Griffith J, Ruthazer R. Measuring the effectiveness of the urban
youth connection: the case for dose-response modeling to demonstrate the impact of an
adolescent substance abuse prevention program. J of Adol Res, 1998.
58.
Bonis PA, Tong MJ, Blatt LM, Conrad A, Griffith JL. A predictive model for the development of
hepatocellular carcinoma, liver failure, or liver transplantation for patients presenting to clinic with
chronic hepatitis C. Am J Gastroenterology, 94(6): 1605-1612, 1999. [PMID: 10364032]
59.
DesJardin JA, Falagas ME, Ruthazer R, Griffith JL, Wawrose D, Schenkein D, Miller K, Snydman
D. Clinical utility of blood cultures drawn from indwelling central venous catheters in hospitalized
patients with cancer. Annals Intern Med, 131:641-647, 1999. [PMID: 10577325]
60.
Link MS, Cesarz CA, Griffith JL, Estes NA 3rd, Wang PJ.
Evaluation of coronary
revascularization to prevent tachycardia recurrences in survivors of ventricular fibrillation. Am J
Cardiol, 83(6): 960-2, 1999. [PMID: 10190419]
61.
Sege R, Stringham P, Short S, Griffith J. Ten years after: examination of adolescent screening
questions that predict future violence-related injury. J Adol Health, 24:395-402, 1999. [PMID:
10401967]
62.
Burns JP, Mitchell C, Outwater KM, Geller M, Griffith JL, Todres I, Truog RD. End-of-life care in
the pediatric intensive care unit after the forgoing of life-sustaining treatment. Critical Care Med,
28(8): 3060-3066, 2000. [PMID: 10966296]
63.
Feldman JA, Fish SS, Beshansky JR, Griffith JL, Woolard RH, Selker HP. Acute cardiac
ischemia in patients with cocaine-associated complaints: results of a multicenter trial. Ann
Emergency Med, 36(5): 469-476, 2000. [PMID: 11054201]
64.
Koc Y, Miller K, Schenkein DP, Griffith JL, Ahktar M, DesJardin J, Snydman DS. Varicella zoster
virus infections following allogeneic bone marrow transplantation: Frequency, risk factors, and
clinical outcome. Biology of Blood and Marrow Transplantation, 6:44-49, 2000. [PMID: 10707998]
65.
Pope JH, Aufderheide TP, Ruthazer R, Woolard RH, Feldman JA, Beshansky JR, Griffith JL,
Selker HP. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J
Med, 342:1163-1170, 2000. [PMID: 10770981]
66.
Burns JP, Mitchell C, Griffith JL, Troug RD. End-of-life care in the pediatric intensive care unit
attitudes and practices of pediatric clinical care physicians and nurses. Crit Care Med, 29(3):
695-696, 2001. [PMID: 11373439]
67.
Moskowitz H, Griffith JL, DiScala C, Sege RD. Serious injuries and deaths of adolescent girls
resulting from interpersonal violence: Characteristics and trends from the United States, 19891998. Arch Pediatr Adolesc Med, 155:903-908, 2001. [PMID: 11483117]
Curriculum Vitae - John L Griffith
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68.
Finlay GA, Joseph B, Rodrigues CR, Griffith JL, White AC. Advanced Presentation of Lung
Cancer in Asian Immigrants: A Case-Control Stud. Chest, 122: 1938-1943, 2002. [PMID:
12475830]
69.
Gill CJ, Griffith JL, Jacobson D, Skinner S, Gorbach SL, and Wilson IB. Relationship of HIV viral
loads, CD4 counts, and HAART use to health-related quality of life. JAIDS, 30:485-492, 2002.
[PMID: 12154339]
70.
Greenfield S, Kaplan SH, Kahn R, Ninomiya J, Griffith JL. Profiling care provided by different
groups of physicians: Effects of patient case-mix (Bias) and physician-level clustering on quality
assessment results. Ann Intern Med, 136:111-121, 2002. [PMID: 11790062]
71.
Kent DM, Hayward RA, Griffith JL,Vijan S, Beshansky JR, Califf M, Selker HP. Independently
derived and validated predictive model for selecting patients with myocardial infarction who are
likely to benefit from tissue plasminogen activator compared with streptokinase. Am J Med,113:
104-111, 2002. [PMID: 12133748]
72.
Kent DM, Griffith J. The Framingham scores overestimated the risk for coronary heart disease in
Japanese, Hispanic, and Native American cohorts. ACP J Club. 136(1): 36. 2002. [PMID:
11829577]
73.
Meyer EC, Burns JP, Griffith JL, Truog RD. Parental perspectives on end-of-life care in the
pediatric intensive care unit. Crit Care Med, 30(1): 226-231, 2002. [PMID: 11902266]
74.
Sarnak MJ, Tighuouart H, Manjunath G, MacLeod B, Griffith JL, Salem D, Levey AS. Anemia as
a risk factor for cardiovascular disease in the atherosclerosis risk in communities (aric) study.
Journal of the American College of Cardiology, 40(1):27-33, 2002. [PMID: 12103252]
75.
Selker HP, Beshansky JR, Griffith JL, For the TPI Trial Investigators. Use of the
electrocardiograph-based thrombolytic predictive instrument to assist thrombolytic and
reperfusion therapy for acute myocardial infarction: a multicenter randomized clinical
effectiveness trial. Ann Intern Med, 137:87-95, 2002. [PMID: 12118963]
76.
Udelson, JE, Beshansky,JR, Ballin,DS, Feldman, JA, Griffith, JL, Heller, GV, Hendel, RC, Pope, JH,
Ruthazer, R, Spiegler, EJ, Woolard, RH, Handler, JH, Selker, HP, Myocardial Perfusion Imaging for
Evaluation and Triage of Patients With Suspected Acute Cardiac Ischemia, JAMA, 288(21) 26932700, 2002. [PMID: 12460092]
77.
Manjunath G, Tighiouart H, Ibrahim H, MacLeod B, Salem DN, Griffith JL, Coresh J, Levey AS,
Sarnak MJ. Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes
in the community. J Am Coll Cardiol, 41(1):47-55, 2003. [PMID: 12570944]
78.
Manjunath G, Tighiouart H, Coresh J, Macleod B, Salem DN, Griffith JL, Levey AS, Sarnak MJ.
Level of kidney function as a risk factor for cardiovascular outcomes in the elderly. Kidney Int.
63(3): 1121-9, 2003. [PMID: 12631096]
79.
Selker HP, Raitt MH, Schmid CH, Laks MM, Beshansky JR, Griffith JL, Califf RM, Selvester RH,
Maynard C, D'Agostino RB, Weaver WD. Time-dependent predictors of primary cardiac arrest in
patients with acute myocardial infarction. Am J Cardiol, 91(3):280-6, 2003. [PMID: 12565083]
80.
Terrin N, Schmid CH, Griffith JL, D'Agostino RB, Selker HP. External validity of predictive
models: a comparison of logistic regression, classification trees, and neural networks. J Clin
Epidemiol, 56(8): 721-9, 2003. [PMID: 12954463]
81.
Amin MG, Tighiouart H, Weiner DE, Stark PC, Griffith JL, MacLeod B, Salem DN, Sarnak MJ.
Hematocrit and left ventricular mass: the Framingham Heart study. J Am Coll Cardiol, 43(7):
1276-82, 2004. [PMID: 15063442]
Curriculum Vitae - John L Griffith
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82.
Coronado BE, Pope JE, Griffith JL, Beshansky JR, and Selker HP. Clinical features, triage, and
outcome of patients presenting to the ED with suspected acute coronary syndromes but without
pain: A multicenter study. The American Journal of Emergency Medicine, 22:568-574, 2004.
[PMID: 15666263]
83.
Kapetanopoulos A, Heller GV, Selker HP, Ruthazer R, Beshansky JR, Feldman JA, Griffith JL,
Hendel RC, Pope JH, Spiegler EJ, Udelson JE. Acute resting myocardial perfusion imaging in
patients with diabetes mellitus: results from the Emergency Room Assessment of Sestamibi for
Evaluation of Chest Pain (ERASE Chest Pain) trial, J Nucl Cardiol, 11(5):570-577, 2004. [PMID:
15472642]
84.
Kent DM, Vijan S, Hayward RA, Griffith JL, Beshansky JR, Selker HP. Tissue plasminogen
activator was cost-effective compared to streptokinase in only selected patients with acute
myocardial infarction. J Clin Epi, 57(8): 843-852, 2004. [PMID: 15485737]
85.
Milch CE, Edmunson JM, Beshansky JR, Griffith JL, Selker HP. Smoking cessation in primary
care: a clinical effectiveness trial of two simple interventions. Preventive Medicine, 38(3): 284294, 2004. [PMID: 14766110]
86.
Pope JH, Ruthazer R, Kontos MC, Beshansky JR, Griffith JL, Selker HP. The Impact of
Electrocardiographic Left Ventricular Hypertrophy and Bundle Branch Block on the Triage and
Outcome of Emergency Department Patients with a Suspected Acute Coronary Syndrome: A
Multicenter Study. Am J of Emergency Med. 22(3):156-63, 2004. [PMID: 15138949]
87.
Scott TM, Tucker KL, Bhadelia A, Benjamin B, Patz S, Bhadelia R, Liebson E, Price LL, Griffith J,
Rosenberg I, Folstein MF. Homocysteine and B vitamins relate to brain volume and white-matter
changes in geriatric patients with psychiatric disorders. Am J Geriatr Psychiatry, 12(6):631-8,
2004. [PMID: 15545331]
88.
Weiner DE, Tighiouart H, Amin MG, Stark PC, MacLeod B, Griffith JL, Salem DN, Levey AS,
Sarnak MJ. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause
mortality: a pooled analysis of community-based studies. J Am Soc Nephrol., 15(5):1307-15,
2004. [PMID: 15100371]
89.
Weiner D, Tighiouart H, Stark P, Amin M, MacLeod B, Griffith J, Salem D, Levey A, Sarnak M.
Kidney disease as a risk factor for recurrent cardiovascular disease and mortality. Am J Kidney
Diseases, 44(2): 198-206, 2004. [PMID: 15264177]
90.
Dansinger, ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins,
Ornish, Weight Watchers, and Zone Diets for Weight Loss and Heart Disease Risk Reduction: A
Randomized Trial. JAMA. 293:43-53, 2005. [PMID: 15632335]
91.
Pope JH, Ruthazer R, Kontos MC, Beshansky JB, Griffith JL, Selker HP. The Impact of
electrocardiographic left ventricular hypertrophy and bundle branch block on the triage and
outcome of ED patients with a suspected acute coronary syndrome: a multicenter study. Am J
Emerg Med, 22(3): 156-164, 2005. [PMID: 15138949]
92.
Vlagopoulos PT, Tighiouart H, Weiner DE, Griffith JL, Pettitt D, Salem DN, Levey AS, Sarnak MJ.
Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact
of chronic kidney disease. Journal of the American Society of Nephrology, 16(11):3403-10, 2005.
[PMID: 16162813]
93.
Weiner DE, Tighiouart H, Vlagopoulos PT, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Effects
of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic
kidney disease. J Am Soc Nephrol. 16:1803-1810, 2005. [PMID: 15857925]
Curriculum Vitae - John L Griffith
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94.
Golan Y, Doron S, Griffith J, El Gamal H, Tanios M, Blunt K, Barefoot L, Bloom J, Gamson K,
Snydman LK, Hansjosten K, Elnekave E, Nasraway SA, and Snydman DR. The impact of gownuse requirement on hand hygiene compliance. Clinical Infectious Diseases 42:370-376, 2006.
[PMID: 16392083]
95.
Scott TM, Peter I, Tucker KL, Arsenault L, Bergethon P, Bhadelia R, Buell J, Collins L, Dashe JF,
Griffith J, Hibberd P, Leins D, Liu T, Ordovas JM, Patz S, Price LL, Qiu WQ, Sarnak M, Selhub J,
Smaldone L, Wagner C, Wang L, Weiner D, Yee J, Rosenberg I, Folstein M. The Nutrition,
Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients
and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry, 21(6):519-28,
2006. [PMID: 16645938]
96.
Weiner DE, Tabatabai S, Tighiouart H, Elsayed E, Bansal N, Griffith J, Salem DN, Levey AS,
Sarnak MJ. Cardiovascular outcomes and all-cause mortality: exploring the interaction between
CKD and cardiovascular disease. Am J Kidney Dis. 48(3): 392-401. 2006. [PMID: 16931212]
97.
Trokel M, Griffith J, Waddimba A, Sege R. Variation in the Diagnosis of Child Abuse in Severely
Injured Infants. Pediatrics, 117: 722-728, 2006. [PMID: 16510652]
98.
Bansal N, Tighiouart H, Weiner D, Griffith J, Vlagopoulos P, Salem D, Levin A, Sarnak MJ.
Anemia as a Risk Factor for Kidney Function Decline in Individuals with Heart Failure. The
American Journal of Cardiology, 99:1137-1142. 2007. [PMID: 17437743]
99.
Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Ruthazer R, Beshansky JR,
Wong JB, Aversano T, and Selker HP. A Geospatial Analysis of Emergency Transport and InterHospital Transfer in ST-Segment Elevation Myocardial Infarction. The American Journal of
Cardiology. 101(1):69-74. 2007. [PMID: 18157968]
100. Elsayed EF, Tighiouart H, Griffith J, Kurth T, Levey AS, Salem D, Sarnak MJ, Weiner DE.
Cardiovascular disease and subsequent kidney disease, Arch Intern Med. 167(11):1130-6, 2007.
[PMID: 17576295]
101. Kent DM, Ruthazer R, Griffith JL, Beshansky JR, Grines CL, Aversano T, Concannon TW,
Zalenski RJ, Selker HP. Comparison of Mortality Benefit of Immediate Thrombolytic Therapy
Versus Delayed Primary Angioplasty for Acute Myocardial Infarction. The American Journal of
Cardiology, 99:1384-1388, 2007. [PMID: 17576295]
102. Pereira AA, Weiner DE, Scott T, Chandra P, Bluestein R, Griffith JL, Sarnak MJ. Subcortical
Cognitive Impairment in Dialysis Patients. Hemodialysis International, 11:309-314, 2007. [PMID:
17576295]
103. Vega-Lopez S, Ausman LM, Griffith JL, and Lichtenstein AH. Interindividual Variability and IntraIndividual Reproducibility of Glycemic Index Values for Commercial White Bread. Diabetes Care,
30:1412-1417, 2007. [PMID: 17384339]
104. Weiner DE, Tighiouart H, Levey AS, Elsayed E, Griffith JL, Salem DN, and Sarnak MJ.
Lowest Systolic Blood Pressure Is Associated with Stroke in Stages 3 to 4 Chronic Kidney
Disease. J. Am. Soc. Nephrol., 18: 960 – 966, 2007. [PMID: 17301190]
105. Weiner DE, Tighiouart H, Griffith JL, Elsayed E, Levey AS, Salem DN, Sarnak MJ. Kidney
Disease, Framingham Risk Scores, and Cardiac and Mortality Outcomes. The American Journal
of Medicine (120): 552e.1-8. 2007.[ PMID: 17576295]
106. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. The
Framingham Predictive Instrument in Chronic Kidney Disease. Journal of the American College of
Cardiology, 50:217-224. 2007.[ PMID: 17631213]
Curriculum Vitae - John L Griffith
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107. Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Ruthazer R, Beshansky JR,
Wong JB, Aversano T, Selker HP. A Geospatial Analysis of Emergency Transport and InterHospital Transfer in ST-Segment Elevation Myocardial Infarction. 101(1): 69-74. 2008. [PMID:
18157968]
108. Elsayed EF, Tighiouart H, Weiner DE, Griffith J, Salem D, Levey AS, Sarnak MJ. Waist-to-hip
ratio and body mass index as risk factors for cardiovascular events in CKD. Am J Kidney Dis,
52(1): 49-57. [PMID: 18514990]
109. Elsayed EF, Sarnak MJ, Tighiouart H, Griffith JL, Kurth T, Salem DN, Levey AS, Weiner DE.
Waist-to-Hip Ratio, Body Mass Index, and Subsequent Kidney Disease and Death. American
Journal of Kidney Diseases, 52(1): 29-38. 2008. [PMID: 18511168]
110. Flaherty EG, Sege RD, Griffith J, Price LL, Wasserman R, Slora E, Dhepyasuwan N, Harris D,
Norton D, Angelilli ML, Abney D, Binns HJ. From suspicion of physical child abuse to reporting:
primary care clinician decision-making. Pediatrics, 122(3):611-9: 2008. [PMID: 18676507]
111. Kent DM, Ruthazer R, Griffith JL, Beshansky JR, Concannon TW, Aversano T, Grines CL,
Zalenski RJ, Selker HP. A Percutaneous Coronary Intervention–Thrombolytic Predictive
Instrument to Assist Choosing Between Immediate Thrombolytic Therapy Versus Delayed
Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction. The American
Journal of Cardiology. 101(6): 790-795. 2008. [PMID: 18328842]
112. Layne JE, Sampson SE, Mallio CJ, Hibberd PL, Griffith JL, Das SK, Flanagan WJ, CastanedaSceppa C. Successful dissemination of a community-based strength training program for older
adults by peer and professional leaders: the people exercising program. J Am Geriatrics Soc,
56(12):2323-9, 2008. [PMID: 19112654]
113. Madan J, Fiascone J, Balasubramanian V, Griffith J, Hagadorn JI. Predictors of Ductal Closure
and Intestinal Complications in Very Low Birth Weight Infants Treated with Indomethacin.
Neonatology, 94:45-51. 2008. [PMID: 18215699]
114. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Saleem DN, and Levey AS. Uric Acid and
Incident Kidney Disease in the Community. J Am Soc Nephrol. 19(6):1204-11. 2008. [PMID:
18337481]
115. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. The
Relationship Between Nontraditional Risk Factors and Outcomes in Individuals With Stage 3 to 4
CKD. American Journal of Kidney Diseases. 51(2): 212-223. 2008. [PMID: 18215699]
116. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Inflammation
and cardiovascular events in individuals with and without chronic kidney disease. Kidney Int.
73(12): 1406-12. 2008. [PMID: 18401337]
117. Castaldi PJ, DeMeo DL, Kent DM, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG,
Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Griffith JL, Silverman EK.
Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency. Am J
Epidemiol. 170(8):1005-13. 2009 [PMID: 19726494].
118. Concannon TW, Griffith JL, Kent DM, Normand SL, Newhouse JP, Atkins J, and Beshansky JR,
Selker HP. Elapsed time in emergency medical services for patients with cardiac complaints: are
some patients at greater risk for delay? Circ Cardiovasc Qual Outcomes. 2(1):9-15. 2009 [PMID:
20031807]
119. Gabbay E, Meyer KB, Griffith JL, Richardson MM, Miskulin DC. Temporal trends in health-related
quality of life among hemodialysis patients in the United States. Clin J Am Soc Nephrol. 5(2):2617. 2009 [PMID: 20019114].
Curriculum Vitae - John L Griffith
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120. Kaplan SH, Griffith JL, Price LL, Pawlson LG, Greenfield S. Improving the Reliability of Physician
Performance Assessment: Identifying the "Physician Effect" on Quality and Creating Composite
Measures. Med Care. 47(4):378-87. 2009. [PMID: 19279511]
121. Weiner DE, Bartolomei K, Scott TM, Price L, Griffith JL, Rosenberg I, Levey AS, Folstein MF,
Sarnak MJ. Albuminuria, Cognitive Functioning, and White Matter Hyperintensities in
Homebound Elders. American Journal of Kidney Diseases. 53(3): 438-447. 2009. [PMID:
19070412]
122. Agganis BT, Weiner DE, Giang LM, Scott T, Tighiouart H, Griffith JL, Sarnak MJ. Depression and
Cognitive Function in Maintenance Hemodialysis Patients. Am J Kidney Dis. 56(4):704-12. 2010.
[PMID 20673602]
123. Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Cohen J, Beshansky JR,
Wong JB, Aversano T, Selker HP. Comparative effectiveness of ST-segment-elevation
myocardial infarction regionalization strategies. Circ Cardiovasc Qual Outcomes. 3(5):506-13.
2010. [PMID: 20664025]
124. Selker HP, Leslie LK, Wasser JS, Plaut AG, Wilson IB, Griffith JL. Comparative Effectiveness
Research as a Conceptual Framework for a Focus on Impact. Clin Transl Sci. 3(2):56-8. 2010.
[PMID: 20443959]
125. Tucker KL, Mattei J, Noel SE, Collado BM, Mendez J, Nelson J, Griffith J, Ordovas JM, Falcon
LM. The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in
Puerto Rican adults: challenges and opportunities. BMC Public Health. 10(107): 2010
[PMID: 2848197]
126. McAlindon TE, Nuite M, Krishnan N, Ruthazer R, Price LL, Burstein D, Griffith J, Flechsenhar K.
Change In Knee Osteoarthritis Cartilage Detected By Delayed Gadolinium Enhanced Magnetic
Resonance Imaging Following Treatment With Collagen Hydrolysate: A Pilot Randomized
Controlled Trial. Osteoarthritis Cartilage. 19(4):399-405. 2011. [PMID: 21251991]
127. Selker HP, Beshansky JR, Ruthazer R, Sheehan PR, Sayah AJ, Atkins JM, Aufderheide TP,
Pirrallo RG, D'Agostino RB, Massaro JM, Griffith JL. Emergency medical service predictive
instrument-aided diagnosis and treatment of acute coronary syndromes and ST-segment
elevation myocardial infarction in the IMMEDIATE trial. Prehosp Emerg Care. 15(2):139-48. 2011.
[PMID: 21366431]
128. Selker HP, Ruthazer R, Terrin N, Griffith JL, Concannon T, Kent DM. Random treatment
assignment using mathematical equipoise for comparative effectiveness trials. Clin Transl Sci.
4(1):10-6. 2011. [PMID: 2134895]
129. Tangri N, Wagner M, Griffith J, Miskulin D, Hodsman A, Ansell D, Naimark D. Effect of Bone
Mineral Guideline Target Achievement on Mortality in Incident Dialysis Patients: An Analysis of
the United Kingdom Renal Registry. Am J Kidney Dis. 57(3):415-21. 2011. [PMCID: 21131115]
130. Wagner M, Ansell D, Kent DM, Griffith JL, Naimark D, Wanner C, Tangri N. Predicting mortality in
incident dialysis patients: an analysis of the United Kingdom Renal Registry. Am J Kidney Dis.
57(6):894-902.2011. [PMID: 21489668]
131. Concannon TW, Nelson J, Goetz J, Griffith JL. A percutaneous coronary intervention lab in every
hospital? Circ Cardiovasc Qual Outcomes.5(1):14-20. 2012. [PMID: 22147882]
132. Moorthy D, Peter I, Scott TM, Parnell LD, Lai CQ, Crott JW, Ordovás JM, Selhub J, Griffith J,
Rosenberg IH, Tucker KL, Troen AM. Status of vitamins B-12 and B-6 but not of folate,
homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated
with impaired cognition and depression in adults. J Nutr. 142(8). 2012. [PMID: 22739363]
Curriculum Vitae - John L Griffith
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133. Selker HP, Beshansky JR, Sheehan PR, Massaro JM, Griffith JL, D'Agostino RB, Ruthazer R,
Atkins JM, Sayah AJ, Levy MK, Richards ME, Aufderheide TP, Braude DA, Pirrallo RG, Doyle
DD, Frascone RJ, Kosiak DJ, Leaming JM, Van Gelder CM, Walter GP, Wayne MA, Woolard RH,
Opie LH, Rackley CE, Apstein CS, Udelson JE. Out-of-hospital administration of intravenous
glucose-insulin-potassium in patients with suspected acute coronary syndromes: the IMMEDIATE
randomized controlled trial. JAMA. 307(18):1925-33. 2012. [PMID: 22452807]
134. Selker HP, Beshansky JR, Griffith JL, D'Agostino RB, Massaro JM, Udelson JE, Rashba EJ,
Ruthazer R, Sheehan PR, Desvigne-Nickens P, Rosenberg YD, Atkins JM, Sayah AJ,
Aufderheide TP, Rackley CE, Opie LH, Lambrew CT, Cobb LA, Macleod BA, Ingwall JS, Zalenski
RJ, Apstein CS. Study design for the Immediate Myocardial Metabolic Enhancement During Initial
Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized
controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndromes in
emergency medical services. Am Heart J. 163(3):315-22. 2012. [PMID: 22424000]
135. Thaler DE, Di Angelantonio E, Di Tullio MR, Donovan JS, Griffith J, Homma S, Jaigobin C, Mas
JL, Mattle H, Michel P, Mono ML, Nedeltchev K, Papetti F, Ruthazer R, Serena J, Weimar C,
Elkind MS, Kent DM. The Risk of Paradoxical Embolism (RoPE) Study: Initial Description of the
Completed Database. Int J Stroke. 2012. [PMID: 22883936]
136. Concannon TW, Nelson J, Kent DM, Griffith JL. Evidence of Systematic Duplication by New
Percutaneous Coronary Intervention Programs. Circ Cardiovasec Qual Outcomes. 2013. [PMID:
23838110]
Curriculum Vitae - John L Griffith
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BOOK CHAPTERS:
Selker HP, Griffith JL, Beshansky JR. Acute cardiac ischemia time-insensitive predictive
instrument (ACI-TIPI): A decision aid for emergency department triage and a measure of
appropriateness of coronary care unit use. Acute Coronary Care in the Thrombolytic Era, 2nd
Edition, Chapter 17. Califf RM, Mark DB, Wagner GS, Editors, St. Louis, Mosby-Year Book, 201211, 1995.
Schmid CH, Griffith JL.
Multivariate classification rules, calibration and discrimination.
Encyclopedia of Biostatistics. Armitage P, Colton T, Editors, John Wiley & Sons, 1998.
ABSTRACTS/SELECTED PAPERS PRESENTED:
Jayes RJ, Larsen GC, Beshansky JR, Griffith JL, D'Agostino RB, Selker HP. How often do
emergency room physicians misread ST segments and does it affect patient care? A multicenter
study. Presented at the Twelfth Annual Meeting of the Society for General Internal Medicine,
Washington DC, April 1989.
Larsen GC, Griffith JL, Beshansky JR, D'Agostino RB,Selker HP. How well do physicians diagnose
and manage acute cardiac ischemia in emergency room patients with electrocardiographic left
ventricular hypertrophy? A multicenter study. Presented at the Annual Meeting of the American
Federation of Clinical Research, Washington DC, April 1989.
Selker HP, Griffith JL, Beshansky JR, Califf RM, D'Agostino RB, Laks MM, Lee KL, Maynard C,
Wagner GS, Weaver WD. The Thrombolytic Predictive Instrument (TPI) Project: Combining clinical
study databases to take medical effectiveness research to the streets. Presented at the Agency for
Health Care Policy and Research Conference, Minneapolis, Minnesota, September 1991.
Chuttani K, Metherall J, Griffith JL, Oates E, Konstam MA, Pauker SG, Oates E, Coleman P, Salem
DN, Konstam MA, Udelson JE. Hepatic uptake of thallium-201 in patients with right coronary artery
disease. Presented at the American Heart Association Annual Meeting, 1992.
Griffith JL, D'Agostino RB, Selker HP. Statistical regression techniques for the construction,
interpretation, and testing of computer neural networks. Presented at the Annual Meeting of the
Society for Medical Decision Making, 1992.
Patil S, Griffith JL, Selker HP. Logistic regression and neural networks as clinical predictive
instruments: does one produce a best model? Presented at the Annual Meeting of the Americal
Federation of Clinical Research, Clin Res, Baltimore, Maryland, 40:347A, May 1992.
Sarasin FP, Reymond JM, Griffith JL, Beshansky JR, Schifferli JA, Unger PF, Scherrer JR, Selker
HP. Impact of the time-insensitive predictive instrument (TIPI) for acute cardiac ischemia (ACI) on
emergency department (ED) treatment speed for chest pain patients. Presented at the Annual
Meeting of the American Federation for Clinical Research, Baltimore, Maryland, May 1992.
Selker HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL,
Maynard C, Wagner GS, Weaver WD. A thrombolytic predictive instrument for acute myocardial
infarction. Presented at the 65th Scientific Session of the American Heart Association, New
Orleans, Louisiana, November, 1992.
Selker HP, Schmid CH, Beshansky JR, Griffith JL, Longstreth WT, O'Connor CM, Caplan LR,
Massey EW, D'Agostino RB, Laks MM, Lee KL, Wagner GS, TPI Investigators. Pulse pressure
predicts thrombolysis-related hemorrhagic stroke. Presented at the 65th Scientific Session of the
American Heart Association, New Orleans, Louisiana, November, 1992.
Curriculum Vitae - John L Griffith
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Griffith JL, Selker HP, Beshansky JR, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL,
Wagner GS, Weaver WD. The thrombolytic predictive instrument (TPI) predictions of thrombolytic
therapy impact on 30-day and 1-year mortality for real-time use. Presented at the Annual Meeting
of the American Federation for Clinical Research, Washington DC, May 1993.Clin Res, 41: 182A,
1993
Griffith JL, Selker HP. The impact on the area under the receiver-operating characteristic curve of
disease prevalence and the distribution of patient characteristics. Presented at the Annual Meeting
of the American Federation for Clinical Research, Washington DC, May 1993. Clin Res, 41:181A,
1993.
Maynard C, Selker HP, Beshansky JR, Griffith JL, Schmid CS, Califf RB, D'Agostino RB, Laks MM,
Lee KL, Wagner GS, Weaver WD. The influence of gender of patient inclusion in developing the
thrombolytic predictive instrument. Presented at the Annual Meeting of the American Federation for
Clinical Research, Washington DC, May 1993. Clin Res, 41:201A, 1993.
Midgette AS, Griffith JL, Califf RB, Dietz SB, Selker HP. A summary scoring system using ECG ST
segment and T wave changes to predict the infarct related artery in acute myocardial infarction.
Presented at the Annual Meeting of the American Federation for Clinical Research, Washington
DC, May 1993. Clin Res, 41:217A, 1993.
Schmid CH, Selker HP, Beshansky JR, Griffith JL, Califf RM, D'Agostino RB, Laks MM, Lee KL,
Maynard C, Wagner GS, Weaver WD. A logistic regression model for the effect of thrombolytic
therapy on the risk of cardiac arrest when some outcomes precede treatment. Presented at the
Annual Meeting of the American Federation for Clinical Research, Washington, DC, April 1993.
Selker, HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL,
Maynard C, Wagner GS, Weaver WD. A thrombolytic predictive instrument for emergency AMI
treatment. Presented at the American College of Cardiology 42nd Scientific Session, Anaheim,
California, March 1993.
Snydman DR, Griffith JL, Kahan F. Risk Factors for third generation cephalosporin (C3) and
Imipenem (IMP) resistant inducible enterobacteriaceae (IE) and Pseudomonas aeruginosa (PA)
among intensive care unit patients (ICU). Presented at the 18th International Congress of
Chemotherapy,1993.
Schmid CS, Selker HP, Beshansky JR, Griffith JL, D'Agostino RB, Raitt MH, Califf RB, Laks MM,
Lee KL, Maynard C, Wagner GS, Weaver WD. A logistic regression model for the effect of
thrombolytic therapy on the risk of cardiac arrest when some outcomes precede treatment.
Presented at the Annual Meeting of the American Federation for Clinical Research, Washington
DC, May 1994. Clin Res, 41:291A, 1994.
Ahmid A, Griffith JL, Foote C, Rastegar H, Estes M, Wang PJ. Tachycardia cycle length as an
independent predictor of cardiac and total mortality in patients with implantable defibrillators.
Presented at the 68th Scientific Session of the American Heart Association, Anaheim, California,
November 1995.
Coronado BE, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group, Division of Clinical
Care Research, New England Medical Center, Boston, MA. Acute Hospital mortality in women and
men with acute cardiac ischemia: A prospective multicenter study. Presented at the Annual
Meeting of the American Federation for Clinical Research, San Diego, May 1995. Clin Res
43:391A, 1995.
Coronado BE, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group. Acute hospital
mortality in women and men with acute cardiac ischemia: A prospective
multicenter study.
Curriculum Vitae - John L Griffith
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Presented at the Annual Meeting of the American Federation of Clinical Research, San Diego,
California, October, 1995. J Invest Med, 43:391A.
Coronado BE, Griffith JL, Beshansky JR, Selker HP, for the ACI-TIPI Investigators. Pain in diabetic
patients with acute myocardial infarction: A prospective multicenter study. Presented at the Annual
Eastern Region American Federation of Clinical Research Meeting, Boston, October 1995. J Invest
Med, 43:503A.
Falagas ME, Snydman DR, Griffith J, Werner BG, Freeman R, Rohrer R, and the Boston Center for
Liver Transplantation CMVIG study group. Predictors of recurrent cytomegalovirus disease in
orthotopic liver transplant recipients. Presented at the 35th Interscience Conference on
Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, California, September 1995.
Falagas ME, Snydman DR, Griffith J, Werner BG, and the Boston Center for Liver Transplantation
CMVIG study group. Cytomegalovirus exposure from the donated organ is a risk factor for
bacteremia in orthotopic liver transplant recipients. Presented at the 35th Interscience Conference
on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, California, September 1995.
Griffith JL, Beshansky JR, Selker HP, for TIPI Working Group, CCHSR, New England Medical
Center, Boston, MA. A multicenter prospective test of electrocardiograph-generated ACI-TIPI
predictions for acute cardiac ischemia. Presented at the Annual Meeting of the American
Federation for Clinical Research, San Diego, May 1995. Clin Res 43:215A.
Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group. A multicenter prospective
validation of computerized electrocardiograph-generated ACI-TIPI risk groups for acute cardiac
ischemia. Presented at the Annual Eastern Region American Federation of Clinical Research
Meeting, Boston, October, 1995. J Invest Med, 43:507A.
Maynard C, Beshansky JR, Griffith JL, Selker HP. The influence of gender on the use of cardiac
procedures in patients presenting to the emergency department: A multicenter study. Presented at
the 68th Scientific Session of the American Heart Association, Anaheim, California, November
1995. Circulation, 92:I-437.
Selker HP, Beshansky JR, Griffith JL for the TIPI Working Group. A controlled trial of the acute
cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) electrocardiograph on
emergency department (ED) triage. Presented at the Annual Eastern Region American Federation
of Clinical Research Meeting, Boston, October 1995. J Invest Med, 43:497A.
Zucker DR, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group Division of Clinical
Care Research Department of Medicine, New England Medical Center, Boston, MA. Accuracy of
Emergency Department diagnosis of acute myocardial infarction in women vs. men: A prospective
multicenter study. Presented at the Annual Meeting of the American Federation for Clinical
Research, San Diego, May 1995. Clin Res 43:404A.
Zucker DR, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group. Accuracy of
emergency department diagnosis of acute myocardial infarction in women vs. men: A prospective
multicenter study. Presented at the American Federation of Clinical Research Meeting, San Diego,
California, October 1995. J Invest Med, 43:404A.
Vannan M, Kettle A,Coakely A, Griffith JL, Udelson JE. Influence of infarct zone viability on left
ventricular remodeling in the year following first anterior myocardial infarction. Presented at the
68th Scientific Session of the American Heart Association, Anaheim, California, November 1995.
Falagas ME, Barefoot L, Griffith J, Ruthazer R, Snydman DR. Risk factors for clinical failure of
antibiotic therapy in patients with intra-abdominal or skin/soft tissue infections treated with
cefotetan, cefoxitin, or ampicillin/sulbactam monotherapy: A retrospective controlled study.
Presented at the 1st European Congress of Chemotherapy, Glasgow, Scotland, May 1996.
Curriculum Vitae - John L Griffith
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Magno AC, Zucker DR, Griffith JL, Selker HP. Analysis of outcomes in 30 to 34 week gestation
(moderate risk) infants: implications for regionalized perinatal programs. Presented at the
American Federation for Clinical Research, Washington D.C., May 1996
Picken HA, Zucker DR, Griffith JL, Beshansky JR, Selker HP. Insurance type and the
transportation to emergency department (EDs) of patients with chest pain or other symptoms
suggestive of acute cardiac ischemia (ACI): the ACI-TIPI insurance study. Presented at the Annual
Meeting of the American Federation for Clinical Research, Washington D.C., May 1996
Cory DA, Schmid CH, Griffith JL, Long WJ, D’Agostino RB, Selker HP. How much do we gain from
complex logistic regression models? Presented at the 156th Annual Meeting of the American
Statistical Association, Chicago, August 1996.
Griffith JL, Schmid CH, Cory DA, Long WJ, D’Agostino RB, Selker HP. Building local binary
predictive models that fit globally. Presented at the 156th Annual Meeting of the American
Statistical Association, Chicago, August 1996.
Falagas ME, Snydman DR, Ruthazer R, Griffith J, Werner BG, and the Boston Center for Liver
Transplantation CMVIG Study Group. Primary cytomegalovirus infection in liver transplantation:
comparison between donor and transfusion transmitted infection.
Presented at the 36th
Interscience Conference on Anitmicrobial Agents and Chemotherapy (ICAAC), New Orleans,
Louisiana, September 1996.
Falagas ME, Snydman DR, Ruthazer R, Griffith J, Werner BG, and the Boston Center for Liver
Transplantation CMVIG Study Group. Lack of value of surveillance blood, urine, and throat
cytomegalovirus cultures in predicting cytomegalovirus disease in liver transplant recipients.
Presented at the 36th Interscience Conference on Anitmicrobial Agents and Chemotherapy
(ICAAC), New Orleans, Louisiana, September 1996.
Falagas ME, Snydman DR, Ruthazer R, Griffith J, Werner BG, and the Boston Center for Liver
Transplantation CMVIG Study Group. Cancer incidence after metronidazole use: a matched
metronidazole user/non-user study of 60,054 subjects. Presented at the 36th Interscience
Conference on Anitmicrobial Agents and Chemotherapy (ICAAC), New Orleans, Louisiana,
September 1996.
Feldman JA, Fish SS, Beshansky JR, Griffith JL, Woolard RH, Selker HP. Acute cardiac ischemia
in patients with cocaine related complaints: results of a large multicenter trial. Presented at the
Eastern Regional Meeting of the American Federation for Medical Research, Boston, September
1996.
Feldman JA, Fish SS, Beshansky JR, Griffith JL, McAfee A, Woolard RH, Selker HP. The accuracy
of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) in patients with
cocaine related complaints: results of the ACI-TIPI clinical trial. Presented at the Eastern Regional
Meeting of the American Federation for Medical Research, Boston, September 1996.
Shamsuddin, Rasmussen ZA, Shaheen, Griffith J. Respiratory rates and oxyhaemoglobin
saturation in normal children in Gilgit, Northern Areas. Presented in Karachi, September 1996.
Valentine J, Griffith JL, Ruthazer R, Kulig J. A predictive model of weapon-carrying among urban
high school students. Presented at the Eastern Regional Meeting of the American Federation for
Medical Research, Boston, September 1996.
Woolard RH, Sidman RD, Moulton AW, Connolly E, Griffith JL, Beshansky JR, Selker HP. Creatine
kinase testing in the emergency department was associated with an increase in admissions of
Curriculum Vitae - John L Griffith
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chest pain patients who did not have acute ischemia. Presented at the Eastern Regional Meeting of
the American Federation for Medical Research, Boston, September 1996.
Griffith JL. The Impact of Sample Size and Outcome Prevalence on the Predictive Performance of
Logistic Regression, Classification Trees, and Neural Networks. Presented at the 157th Annual
Meeting of the American Statistical Association, Anaheim, August 1997.
Burns J, Outwater K, Geller M, Griffith J, Todres D, Truog R. Ventilator withdrawal at the end-oflife. Presented at the Annual Meeting of Pediatrics, November 1997.
Balk EM, Griffith JL, Beshansky JR, Selker HP. Vomiting as a predictor of acute myocardial
infarction in the emergency department. Presented at the Annual Meeting of the Society for
General Internal Medicine, April 1998.
Pope JH, Aufderheide TP, Ruthazer R, Woolard RH, Beshansky JR, Griffith JL, Selker HP. Missed
diagnoses of acute myocardial infarction in the emergency department: Results from a multicenter
study. Presented at the Annual Meeting of the Society for General Internal Medicine, April 1998.
Griffith JL, Ruthazer R, Schmid C, Terrin N. A comparison of regression models, classification
th
trees, and neural networks for the prediction of cardiac complications. Presented at the 158
Annual Meeting of the American Statistical Association, Dallas, August 1998.