Molly S. Crowe Doctoral Candidate West Virginia University Department of Psychology PO Box 6040 Morgantown, WV 26506-6040 EDUCATION: http://community.wvu.edu/~sgk008/crowe.html e-mail: [email protected] Ph.D. West Virginia University, Morgantown, WV Psychology (Behavioral Neuroscience) May 2016 (expected) Master of Science May 2014 Bachelor of Arts May 2011 West Virginia University, Morgantown, WV Psychology (Behavioral Neuroscience) West Chester University, West Chester, PA Major in Psychology Minor in French GPA: 3.9 SPECIAL ACHEIVEMENTS AND HONORS: Department of Psychology Student Research Fund West Virginia University grant for Dissertation Research May 2015 Eberly College of Arts and Sciences Doctoral Student Research Fund West Virginia University grant for Dissertation Research Barry Edelstein Graduate Student Research Award West Virginia University award for best published thesis Monique and George Braude Student Travel Award International Cannabinoid Research Society Conference Behavioral and Biomedical Sciences Training Scholarship West Virginia University funds for dissertation research May 2015 March 2015 June 2014 February 2014 Department of Psychology Travel Award West Virginia University funds for conference travel June 2013 Department of Psychology Student Research Fund West Virginia University grant for Master’s Thesis May 2013 Psychology Graduate Honors West Chester University Research, Academics, and Service awards May 2011 Psi Chi Psychology Honor Society President (elected position) March 2010-April 2011 M.S.Crowe cv p.1of 3 Dean’s list, West Chester University RELEVANT RESEARCH EXPERIENCE: Graduate Research Associate West Virginia University, Morgantown, WV Cannabinoid Research PI: Dr. Steven G. Kinsey Volunteer Research Assistant Thomas Jefferson University, Philadelphia, PA Autism and Sensory Perception Study PI: Dr. Roseann Schaaf Research Assistant West Chester University, West Chester, PA Transition to College Study PI: Dr. Susan Gans and Dr. Vanessa Johnson Researcher Independent Study West Chester University, West Chester, PA Endocrinology of pregnant women: cortisol level fluctuation PI: Dr. Susan Gans 2007-2011 June 2012-Present July 2011-April 2012 January 2010-January 2011 May 2010-August 2010 RESEARCH SUPPORT: • 2014 – 2016 Research Training Fellowship T32. (PI: Albert Berrebi) PUBLICATIONS: • Crowe, MS, Leishman, E, Gujjar, R, Mahadevan, A, Banks, M, Bradshaw, HB, Kinsey, SG. (2015). Dual inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice. British Journal of Pharmacology. 172 (7):1700-1712. • Crowe, MS, Nass, SR, Gabella, K, Kinsey, SG. (2014). The endocannabinoid system modulates stress, emotionality, and inflammation. Brain, Behavior, and Immunity. 42: 1-5. • Ignatowska-Jankowska, BM, Ghosh, S, Crowe, MS, Kinsey, SG, Niphakis, MJ, Abdullah, RA, O'Neal, ST, Walentiny, DM, Wiley, JL, Cravatt, BF, and Lichtman, AH. (2014). In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: Antinociceptive activity without cannabimimetic side effects. British Journal of Pharmacology. 171(6):1392-1407. • Wilkerson, JL, Ghosh, S, Bagdas, D, Mason, BL, Crowe, MS, Hsu, K, Wise, LE, Kinsey, SG, Damaj, MI, Cravatt, BF and Lichtman, AH. Diacylglycerol lipase beta inhibition reverses nociceptive behavior in mouse models of inflammatory and neuropathic pain. Under Review. • Baillie, G, Crowe, MS, Ignatowska-Jankowska, BM, Kinsey, SG, Ross, R, and Lichtman, AH. Analgesic effects of a novel selective positive allosteric cannabinoid receptor modulator. Under Review. M.S.Crowe cv p.2of 3 • • • Nguyen, L, Thomas, KL, Luke-Wold, BP, Cavendish, JZ, Crowe, MS, Matsumoto, R. Dextromethorphan: an update on its utility for neurological and neuropsychiatric disorders. In preparation. Crowe, MS, Pink, M, Peluso, S, & Kinsey, SG. Analgesic and anti-inflammatory effects of a reversible MAGL inhibitor. In preparation. Nass, SR, Gabella, K, Jones, M, Crowe, MS, and Kinsey, SG. Withdrawal from the cannabinoids THC and JWH-018 alters anxiety and depressive-like behavioral measures in mice. In preparation. PRESENTATIONS: • Crowe, MS, Leishman, E, Gujjar, R, Mahadevan, A, Banks, M, Bradshaw, HB, & Kinsey, SG (March 2015). Treating sciatic pain by combining a current pain drug with an experimental endocannabinoid drug. Poster presented at the Presidential Neuroscience Research Symposium, Morgantown, WV. • Taylor, RL, Crowe, MS, and Kinsey, SG (2015). Neuropathic pain is attenuated by the cannabinoid enzyme inhibitor KML29 and the GABA analogue gabapentin. Poster presented at the 16th Annual National Conference for McNair Scholars, College Park, Maryland. • Crowe, MS, Pink, M, Peluso, S, Kinsey, SG (February 2015). The novel cannabinoid enzyme inhibitor IPI-0595 blocks neuropathic pain and gastric inflammation. Poster presented at the E.J. Van Liere Memorial Convocation and HSC Research Day, Morgantown, WV. • Crowe, MS, Leishman, E, Gujjar, R, Mahadevan, A, Banks, M, Bradshaw, HB, & Kinsey, SG (November, 2014). Inhibition of cyclooxygenases and the endocannabinoid enzyme monoacylglycerol lipase synergistically reduces neuropathic pain in mice. Poster presented at the Society for Neuroscience, Washington, DC • Crowe, MS and Kinsey, SG (November, 2014). Restraint stress-induced delay of cutaneous wound healing is not reversed by monoacylglycerol or fatty acid amide hydrolase inhibition. Poster presented at the Carolina Cannabinoid Collaborative, Winston-Salem, NC • Taylor, RL, Crowe, MS, and Kinsey, SG (November, 2014). The selective monoacylglycerol lipase inhibitor, KML29 attenuates neuropathic pain in mice. Poster presented at the Carolina Cannabinoid Collaborative, Winston-Salem, NC • Crowe, MS, Leishman, E, Gujjar, R, Mahadevan, A, Banks, M, Bradshaw, HB, & Kinsey, SG (June, 2014). Attenuating neuropathic pain through dual inhibition of cyclooxygenase and monoacylglycerol lipase. Poster presented at the International Cannabinoid Research Society conference, Baveno, Italy. • Crowe, MS, Leishman, E, Gujjar, R, Mahadevan, A, Banks, M, Bradshaw, HB, & Kinsey, SG (October, 2013). Dual Cyclooxygenase and Monoacylglycerol Lipase Inhibition Synergistically Attenuates Neuropathic Pain. Paper presented at the Carolina Cannabinoid Collaborative, Richmond, VA • Ignatowska-Jankowska, BN, Baillie, GL, Kinsey SG, Crowe, MS, O’Neal, ST, Ghosh, S, Gamage, T, Wiley, JL, Greig, IR, Zanda, M, Zanato, C, Ross, R, Lichtman, AH. (October, 2013). Anti-Allodynic Effects of ZCZ011: a Novel CB1 Positive Allosteric Modulator. Paper presented at the Carolina Cannabinoid Collaborative, Richmond, VA • Ghosh, S, Wilkerson, J, Hsu, K, Crowe, MS, Kinsey, SG, Cravatt, BF, Lichtman, AH (October, 2013). KT-109, A Selective Diacylglycerol Lipase Beta Inhibitor Produces Antinociceptive Effects in the LPS Inflammatory Pain Mouse Model. Paper presented at the Carolina Cannabinoid Collaborative, Richmond, VA M.S.Crowe cv p.3of 3 • • • Crowe, MS, Ignatowska-Jankowska, BM, Niphakis, MJ, Cravatt, BF, Lichtman, AH, & Kinsey, SG (June, 2013). Gastroprotective effects of the monoacylglycerol lipase inhibitor KML29 in mice. Poster presented at the International Cannabinoid Research Society conference, Vancouver, BC, Canada. Crowe, MS, Ignatowska-Jankowska, BM, Niphakis, MJ, Cravatt, BF, Lichtman, AH, & Kinsey, SG (February, 2013). The monoacylglycerol lipase inhibitor KML29 protects against diclofenac-induced gastric hemorrhages. Poster presented at the E.J. Van Liere Memorial Convocation and HSC Research Day, Morgantown, WV. Crowe, MS, Ignatowska-Jankowska, BM, Niphakis, MJ, Cravatt, BF, Lichtman, AH, & Kinsey, SG (February, 2013). Inhibition of monoacylglycerol lipase attenuates nonsteroidal antiinflammatory drug-induced gastric hemorrhages in mice. Poster presented at the Research Horizons Day, Morgantown, WV. TEACHING AND MENTORING: 2014 Biological Foundations of Behavior Lab (PSYCH 301) Department of Psychology, West Virginia University. Upper level undergraduate lab. Six sections, 130 undergraduate students. Perception (PSYC425). Guest Lecturer. Department of Psychology, West Virginia University. Upper level course on fundamentals of sensation and perception. Presented on object recognition to 35 undergraduate students 2013 Biological Foundations of Behavior Lab (PSYCH 301) Department of Psychology, West Virginia University. Upper level undergraduate lab. Six sections, 120 undergraduate students. Biological Foundations of Behavior (PSYCH 301) Guest Lecturer. Department of Psychology, West Virginia University. Upper level undergraduate course lecture. Presented on behavioral genetics to 120 undergraduate students. Perception (PSYC425). Guest Lecturer. Department of Psychology, West Virginia University. Upper level course on fundamentals of sensation and perception. Presented on visual attention to 34 undergraduate students Students Mentored WVU undergraduate research assistants: Ben Rein (2015), Malosree Maitre (2014), Austin McKitrick (2014-2015), Kate Cardullo (2014-2015), Rachael Taylor (2014), Carly Buser (Capstone 2013-2014), Benjamin Dearborn (2013), Allie Nwosu (2013), Maggie Jones (Honors thesis 2013-2014 ), Khristina Bankhead (2012-2014), Anthony D’Ovidio (2012), Austin Sanders (2012), Kristina Welch (2012), Erica Cole (Honors thesis, 2012), Jessica Silverman (2012), Kelsey Wilson (Honors thesis, 2012) SERVICE ACTIVITIES: Ad Hoc Reviewer for: • Pain • Journal of Pain • British Journal of Pharmacology Behavioral Neuroscience Training Committee Honors Thesis Committee Member; Kelsey Wilson Honors Thesis Committee Member; Erica Cole May 2013-Present December, 2012 November, 2012 M.S.Crowe cv p.4of 3 PROFESSIONAL AFFILIATIONS: Society for Neuroscience International Cannabinoid Research Society Meeting of Behavioral and Biomedical researchers Neuroscience Journal Club Neuroscience Research Group 2014-Present 2012-Present 2012-Present 2012-Present 2012-Present SKILLS: CITI Biomedical Research certified Fluent in French M.S.Crowe cv p.5of 3 REFERENCES: • Dr. Steven Kinsey Professor/Adviser, West Virginia University [email protected]……………….………………….…….304.293.1685 • Dr. Melissa Blank Professor, West Virginia University [email protected]……………….………………….…….304.293.8341 • Dr. Miranda Reed Professor, West Virginia University [email protected]………………………………………...304.293.1787 M.S.Crowe cv p.6of 3
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