to know more - Datar Genetics Limited

SECURE MY TUMOR
ALIVE
DID YOU KNOW ?
Your tumor is unique and
contains important information
that may be critical to
your treatment and survival.
Tumors are NOT preserved
Alive by your hospital and
are routinely discarded.
TM
SecureMyTumor preserves your
tumor Alive so you can
access the best personalized
treatments and diagnostics,
worldwide.
Not preserving your tumor
Alive may limit your
treatment options.
securemytumor.com
datarpgx.com
Preserving Your Tumor ALIVE Allows You To:
Awaken your immune system to ght cancer. Cancer vaccines are made of unique markers (that are only
present in your tumor). These vaccines awaken your immune system and activate it to ght your cancer and help
extend time in remission with relatively no side effects.
Experiment with chemo in the lab, not on your body. Chemo has toxic side effects, and so identifying the right
choice from the start is critical. Yet chemo choices are often eliminated by trial and error. Chemo resistance testing
determines the most effective chemo or drug combination for you.
Target cancer cells and spare your healthy cells. Identifying unique markers in your tumor helps your oncologist more
precisely target the cancer cells and spare the healthy cells. Genetic sequencing screens for hundreds of targets that help
prioritize the drugs and treatment choices.
* Not a comprehensive list, and some are experimental
Your tumor can ONLY be preserved ALIVE at the time of surgery. DO NOT LET ANYONE DISCARD IT
How long can my tumor be stored ?
It can be stored for very long periods of time without any loss in
cell viability (typically ten years or more).
Doesn't my hospital / doctor store my tumor ?
No one today preserves your tumor alive. All hospitals embed
tumors in parafn (dead too). Viable preservation is costly
because it is sensitive and difcult to handle within short time
windows, and because it requires hours of delicate and sterile
processing. SecureMyTumor specializes in viable processing.
With SecureMyTumor, you have the option to preserve viably, or
in multiple formats for virtually any kind of use.
Tumor is always scarce and limited, and generally, patients do
not get as much as they would like to use. For vaccines, the
more cells you have, the more vaccine you can manufacture, and
the more tumor you can spare for diagnostics. Call us, we can
guide you and help you prioritize.
Does it make sense to store a uid tumor (Ascitis) ?
And is an Ascitis less potent than a solid tumor ?
Yes absolutely. Contrary to the general perception, an Ascitis is
just as potent. My trial requires a minimum cell count, but my
tumor is too small.
How do I know if it will yield enough cells ?
What about ownership ? With SecureMyTumor patients have
full control over their tumor tissue. This is a serious issue, and
several patients report frustrations over samples processed by
hospitals. Tumor samples embedded in parafn (FFPE) blocks
by a hospital belong to the hospital, not the patient. The patient
has no right to access or to use the FFPE sample for his/her
own. The hospital typically uses your tumor sample for its own
research.
I need a kit right away, can you help ?
While we typically ship overnight, we understand that
emergency kits are sometimes needed. We can ship same-day
delivery, hire a driver, or y it ourselves if needed. We can also
send instructions for collection and then shipment back to our
facility without a Kit (while a sub optimal solution, it is a good
option when all alternatives fail).
I've had chemo; can I still store my tumor viably ?
Yes. If you are going through surgery, it means you have tumor
regardless of the previous chemo, and the tumor is just as
valuable before or after the chemo.
What type of tumors do you preserve ?
All diseases. Solid and uid. All sizes. Biopsies too.
How much tumor do you need ?
My tumor is very small, does it make sense to store it ?
All tissue is valuable. We recommend storing all tumor tissue
and uid (uid is just as good as solid). The more you have, the
more potential options you can explore.
securemytumor.com
datarpgx.com
There is no way to predict how many cells one would get from a
certain volume of tumor before processing it. We have had
biopsies that yielded more than 300 million cells, and tennis ball
size tumors that yielded less than 5 million cells. This is because
every tumor is different and unique. We have analyzed hundreds
of tumors to conclude that there is NO correlation between size
of tumor and how many cells the tissue (or ascites) yields in
terms of cell count. Generally the minority of our patients that do
not get as much cells as they would like can store a second
tumor (to add the cells up).
Doesn't my cancer mutate/change ?
Will my tumor be useful for making a vaccine in the future?
Yes, cancer evolves and mutates, but it adds mutations
as opposed to replacing old once, and so for the purpose of
the vaccine (identifying cells that are unique to the cancer and
not present in the rest of the body), old tumor works just as well.
Having the tumor from the rst surgery can even help you avoid
a second surgery in the case of recurrence.
What factors could cause the process to be unsuccessful ?
Tissue dies over time, so delayed shipments, delays in customs
clearance, delayed pick ups, weekend deliveries that go wrong,
etc.
What if the storage facility loses power ?
Our storage facility is state-of-the-art, with back-up systems in
place for power outages and the long term storage is in liquid
nitrogen which does not require power. It can be fully operational
for weeks without electricity.