This article was originally published in Brain Mapping: An Encyclopedic Reference, published by Elsevier, and the attached copy is provided by Elsevier for the author's benefit and for the benefit of the author's institution, for non-commercial research and educational use including without limitation use in instruction at your institution, sending it to specific colleagues who you know, and providing a copy to your institution’s administrator. All other uses, reproduction and distribution, including without limitation commercial reprints, selling or licensing copies or access, or posting on open internet sites, your personal or institution’s website or repository, are prohibited. For exceptions, permission may be sought for such use through Elsevier's permissions site at: http://www.elsevier.com/locate/permissionusematerial Doré B.P., and Ochsner K.N. (2015) Emotion Regulation. In: Arthur W. Toga, editor. Brain Mapping: An Encyclopedic Reference, vol. 3, pp. 53-58. Academic Press: Elsevier. Author's personal copy Emotion Regulation BP Dore´ and KN Ochsner, Columbia University, New York, NY, USA ã 2015 Elsevier Inc. All rights reserved. Glossary Amygdala A subcortical emotion generation region that registers arousal and stimulus salience. Domain-general control regions Prefrontal, parietal, and cingulate regions of the brain that support controlled processing in general, including the implementation of emotion regulation strategies like reappraisal. Dorsal anterior cingulate cortex (dACC) A prefrontal control region that detects conflict and signals adjustments in controlled processing. Dorsolateral prefrontal cortex (dlPFC) A prefrontal control region that supports maintenance and manipulation of information in working memory. Dorsomedial prefrontal cortex (dmPFC) A brain region that supports reappraisal and is known to underlie mentalstate judgments. Emotion generation The process by which a situation is selected, attended to, and appraised as goal-relevant, giving rise to an emotional response. Emotion generation regions Cortical and subcortical regions of the brain that support emotion generation and are modulated by regulation strategies like reappraisal. Emotion regulation The recruitment of strategies that influence one or more stages of the emotion generation process and thereby modify emotional responses. Many of history’s greatest minds hold that life is tragic. Some of life’s tragedies are major, like losing a loved one. And many of them are small, like arriving at work and realizing that you forgot your keys at home. These events elicit emotional responses ranging from grief to sadness, anger, and frustration, among many others. How, exactly, does the brain enable us to regulate these emotions? The answer to this question has implications for our mental and physical well-being (DeSteno et al., 2013; Gross & Munoz, 1995) and our scientific understanding of brain function. In recent years, an entire field of research has emerged devoted to understanding this ability. Here, we summarize this research and outline a brain-based model of emotion regulation that focuses on the neural systems underlying the cognitive control of emotion. The Process Model of Emotion Emotion Generation Before turning to how emotions can be regulated, it is useful to consider what emotions are and how they arise. Some theorists distinguish between affective responses, which are valenced (i.e., positive or negative) evaluations that reflect an assessment of the momentary goodness or badness of a stimulus, and emotions, which entail a richer appraisal of the meaning of the stimulus along multiple dimensions (see, e.g., Barrett, 2012; Brain Mapping: An Encyclopedic Reference Emotional response A psychological state that involves subjective experience (e.g., feelings of valence, arousal, and/ or particular categories of emotion), behavior (e.g., facial, bodily, and verbal), and peripheral physiology (e.g., heart rate and respiration). Inferior parietal cortex (iPC) A parietal control region that supports controlled shifts of attention. Insula A cortical emotion generation region that supports integration of affective and visceral–somatic information. Lateral temporal cortex A brain region that supports reappraisal and is known to reflect semantic and perceptual processing. Reappraisal A particularly powerful and well-studied emotion regulation strategy that involves changing the way one thinks about the meaning of a stimulus. Ventral striatum A subcortical emotion generation region that supports encoding and construction of stimulus value. Ventrolateral prefrontal cortex (vlPFC) A prefrontal control region that supports the inhibition and controlled selection of semantic information. Ventromedial prefrontal cortex (vmPFC) A brain region that may underlie individual or group differences in reappraisal ability and is known to underlie fear extinction, value computation, and self-processing. Lazarus, 1991). Given that we are at a relatively early stage of brain-imaging research on emotion and its regulation, we take an inclusive stance and group both terms under the umbrella category of emotional responses that can be regulated. As shown in Figure 1, contemporary views hold that emotion generation involves at least four distinct stages (adapted from Gross, 1998; Ochsner, Silvers, & Buhle, 2012). An emotion is generated when (1) a situation is encountered (i.e., stimuli embedded within a context are perceived), (2) one or more features of this situation are attended to, (3) these features are appraised as positive or negative in a variety of ways depending on their relevance to current and chronic goals, and (4) a corresponding pattern of experience, behavior, and/or peripheral physiology is produced. Although in prototypical emotional responses this pattern is described as coordinated (e.g., feelings of fear, escape behavior, and increased heart rate arise together upon seeing a snake), research on this topic suggests that coherence of these variables may be less than originally hypothesized (Mauss, Levenson, McCarter, Wilhelm, & Gross, 2005). Emotion Regulation Emotion regulation involves the modification of emotional responses via the recruitment of strategies that influence particular stages of the emotion generation process. Figure 1 http://dx.doi.org/10.1016/B978-0-12-397025-1.00153-6 Brain Mapping: An Encyclopedic Reference, (2015), vol. 3, pp. 53-58 53 Author's personal copy 54 INTRODUCTION TO SOCIAL COGNITIVE NEUROSCIENCE | Emotion Regulation Emotion regulation Situation selection and modification Situation Attention deployment Attention Cognitive change Response modulation Appraisal Response Emotion generation Figure 1 The process model of emotion. See text for details. Emotion generation Domain-general control and other relevant regions Figure 2 Brain mechanisms of emotion regulation. See text for details. illustrates four such families of emotion regulation strategies, organized in terms of the stage of the emotion generation process that they impact. Note that although the goal to regulate one’s emotions and the strategies used to do so could theoretically be activated and operate implicitly and automatically, almost all neuroscience studies of emotion regulation have focused on strategies that are explicitly motivated, cued, and implemented (Gyurak, Gross, & Etkin, 2011). The most forward-thinking families of strategies, situation selection and modification, entail efforts to influence the kinds of situations that one will experience or to modify relevant features of those situations once you are in them. Next, attention deployment involves directing attention toward or away from features of a given situation, as when distracting oneself. After that, cognitive change strategies target our appraisals, changing the ways we think about an attended stimulus in order to change its emotional impact. The prototypical cognitive change strategy, reappraisal, involves deliberately changing one’s interpretation of and/or personal connection to a stimulus. Finally, response modulation strategies target and modulate the behavioral component of the emotional response, for example, emotional facial expressions. Brain Mechanisms of Emotion Regulation Although behavioral studies have examined how the strategies listed in the preceding text differ in terms of their impact on the emotional response (e.g., Gross & John, 2003; Kross & Ayduk, 2008; Richards & Gross, 2000), to date, the majority of brainimaging research has focused on the prototypical cognitive change strategy, reappraisal. Recent meta-analyses of over 40 brain-imaging studies of reappraisal (Buhle et al., 2013; Diekhof, Geier, Falkai, & Gruber, 2011; Kalisch, 2009) in healthy adults suggest that implementing reappraisals involves recruitment of domain-general control regions, including the prefrontal, parietal, and cingulate cortices, in order to influence activity in the subcortical and cortical emotion generation regions, including the amygdala, ventral striatum, and insula (Figure 2). Emotion Generation Regions First, we consider brain regions that support the valenced evaluation of stimuli and thereby the generation of emotional responses. Activity in these regions is associated with the experience of emotional states (Kober et al., 2008) and is modulated by regulation strategies like reappraisal (Buhle et al., 2013; Diekhof et al., 2011; Kalisch, 2009; Ochsner et al., 2012). The amygdala. The amygdala is a subcortical region that detects affectively salient stimuli, modulates activity in perceptual and memory systems for further processing of these stimuli, and can trigger appropriate behaviors (Cunningham, Van Bavel, & Johnsen, 2008; Whalen, 1998). Although early theories of amygdala function emphasized its role in negative affect (e.g., LeDoux, 1998), it has become clear that this region also responds to positive, novel, and ambiguous stimuli (e.g., Phelps, 2006). Amygdala activity is modulated by reappraisal in studies that use negative stimuli as well as studies using positive stimuli, although studies of the latter are far less represented in the current literature (Ochsner et al., 2012). In the context of emotion regulation, amygdala activity is thought to reflect the current salience and arousal level elicited by the viewed or regulated stimulus. The ventral striatum. The ventral portion of the striatum is involved in encoding and constructing representations of Brain Mapping: An Encyclopedic Reference, (2015), vol. 3, pp. 53-58 Author's personal copy INTRODUCTION TO SOCIAL COGNITIVE NEUROSCIENCE | Emotion Regulation stimulus value that guide learning and motivate behavior. As a key region of the mesolimbic dopamine reward pathway, the ventral striatum receives dopaminergic input from the midbrain ventral tegmental area (Haber & Knutson, 2009; Schultz, Dayan, & Montague, 1997). Functional imaging studies show that the ventral striatum responds to expectation and receipt of a wide variety of rewards, including sweet liquids, money, music, attractive faces, and social fairness (e.g., Cloutier, Heatherton, Whalen, & Kelley, 2008; King-Casas et al., 2005; O’Doherty, 2004; Salimpoor, Benovoy, Larcher, Dagher, & Zatorre, 2011). Although emotion regulation studies have reported modulation of the ventral striatum much less commonly than modulation of the amygdala (Buhle et al., 2013) – in large part because they have infrequently utilized appetitive/positive stimuli – studies employing mediation analysis support the idea that the reappraisal of aversive stimuli can rely on independent pathways of amygdala and ventral striatum modulation (Kober et al., 2010; Wager, Davidson, Hughes, Lindquist, & Ochsner, 2008). The insula. The insula is a cortical region hidden beneath overlying folds of the temporal and parietal cortices. Based on patterns of anatomical connectivity (Augustine, 1996; Craig, 2009) and meta-analyses of neuroimaging studies (e.g., Chang, Yarkoni, Khaw, & Sanfey, 2013), it has been proposed that the insula supports the integration of affective and visceral–somatic information involved in interoceptive states, like emotion (Garfinkel et al., 2013; Zaki, Davis, & Ochsner, 2012), including the experience of disgust and pain. In studies of reappraisal, insula modulation has been observed far less commonly than modulation of either the amygdala or ventral striatum (Ochsner et al., 2012). Domain-General Control Regions Next, we turn to a set of brain regions previously identified as critical in the ability to exert cognitive control over the contents of memory, focus of attention, and language functions. Metaanalyses support the idea that reappraisal is implemented by these domain-general control regions (Buhle et al., 2013; Diekhof et al., 2011; Kalisch, 2009), including the dorsal anterior cingulate cortex (dACC), dorsolateral prefrontal cortex (dlPFC), inferior parietal cortex (iPC), ventrolateral prefrontal cortex (vlPFC), and dorsomedial prefrontal cortex (dmPFC). The dorsolateral prefrontal cortex and inferior parietal cortex. When reappraising an affectively salient stimulus, a set of cognitive control regions are engaged. Chief among these are the dlPFC and iPC, which together form the brain’s frontoparietal network thought to underlie goal-directed (i.e., top-down) control of attention and working memory (Corbetta & Shulman, 2002; Wager, Jonides, & Reading, 2004). Of the two components of this network, studies suggest that the dlPFC is involved primarily in the maintenance and manipulation of information in working memory (Ptak, 2012; Wager & Smith, 2003) whereas the iPC is more involved in triggering shifts of attention between external stimuli and internal representations (Ptak, 2012; Wager & Smith, 2003). In the context of emotion regulation, the dlPFC and iPC may work together to attend to, maintain, and manipulate semantic information related to stimulus qualities, appraisal representations, and regulatory goals. The ventrolateral prefrontal cortex. Another region subserving mechanisms of controlled processing, the vlPFC is involved in 55 language production (Snyder et al., 2010) and, more generally, the selection and controlled retrieval of information from semantic memory (Badre & Wagner, 2007). This region is also known to support controlled inhibition of prepotent behavioral responses (Aron, Robbins, & Poldrack, 2004; Levy & Wagner, 2011). Reappraisal is theorized to depend deeply on memory and language processes to support the generation of alternative narratives about the meaning of affective stimuli, which also involves the inhibition of representations that generate one’s initial affective response. As such, it is likely that vlPFC activation in studies of reappraisal reflects computations supporting some or all of these functions. The dorsal anterior cingulate cortex. Implementing control during reappraisal may require detection of conflict between competing responses. Models of dACC function emphasize its role as a nexus region that detects and signals the need for adjustments in cognitive control (Botvinick, Braver, Barch, Carter, & Cohen, 2001; Miller & Cohen, 2001; Ridderinkhof, Ullsperger, Crone, & Nieuwenhuis, 2004). In the context of emotion regulation, dACC may serve to signal the conflict between one’s initial appraisal of a stimulus and a desired reappraisal of it or conflicts between current and desired levels of affect. Other Regions Relevant to Emotion Regulation Two regions that do not map cleanly onto cognitive control systems – the dorsomedial prefrontal cortex (dmPFC) and the lateral temporal cortex – also are consistently observed to increase their activity during reappraisal. A third region, the ventromedial prefrontal cortex (vmPFC), has not been consistently observed during reappraisal (Buhle et al., 2013), but has been variably proposed to support affect generation or controlled regulation or to act as a mediator of the effects of control regions on emotion generation regions (see Diekhof et al., 2011; Roy, Shohamy, & Wager, 2012). The dorsomedial prefrontal cortex. The dmPFC is a cortical region known to support mental-state judgments about transient or enduring qualities of oneself or other people (Denny, Kober, Wager, & Ochsner, 2012; Mitchell, 2009). Activation in this region is also reliably observed during reappraisal, alongside domain-general control regions, suggesting that processes recruited to support introspection about and assessments of mental states also support emotion regulation. This observed activity may reflect attempts to judge one’s own emotional state during the reappraisal period or to gauge and reconsider the mental states of individuals depicted in the evocative stimuli. The lateral temporal cortex. Reappraisal also consistently engages a swath of the lateral temporal cortex, an area of the brain thought to support abstract representation of semantic and perceptual information (Binder & Desai, 2011; Visser & Ralph, 2011). This pattern of findings suggests that the cognitive control of emotion involves using control systems to modulate semantic and perceptual processing of a stimulus, which in turn leads to modulation of emotion generation regions like the amygdala (Buhle et al., 2013). The ventromedial prefrontal cortex. The vmPFC is known to directly track reward outcome magnitude in a variety of contexts and is thought to compute an integrative value signal that takes into account stimulus history and context (Fehr & Rangel, 2011; Schoenbaum, Saddoris, & Stalnaker, 2007). Interestingly, this Brain Mapping: An Encyclopedic Reference, (2015), vol. 3, pp. 53-58 Author's personal copy 56 INTRODUCTION TO SOCIAL COGNITIVE NEUROSCIENCE | Emotion Regulation region is crucial to reversal learning and extinction of conditioned fear, as well as placebo analgesia (Delgado, Gillis, & Phelps, 2008; Diekhof et al., 2011; Schiller & Delgado, 2010). Although several theorists have proposed that the vmPFC plays a role in emotion regulation broadly construed, this region is not consistently activated in studies of reappraisal (Buhle et al., 2013). However, this region is known to relate to individual and group differences in reappraisal efficacy (Erk et al., 2010; Johnstone, van Reekum, Urry, Kalin, & Davidson, 2007; Wager et al., 2008) and may play a general role in implicit forms of emotion regulation (Gyurak et al., 2011). Extending the Model to Other Regulatory Phenomena Having established a model of the basic brain mechanisms underlying emotion regulation, research has begun to ask how these brain systems may contribute to other forms of regulatory and social cognitive phenomena. Affect labeling. Even in the absence of a goal to regulate, simply verbally labeling feelings can have a regulatory effect in some circumstances. Recent research demonstrates that engaging in affect labeling when viewing an affective stimulus leads to increases in vlPFC activity, decreases in amygdala activity (Torrisi, Lieberman, Bookheimer, & Altshuler, 2013), and attenuated intensity of self-reported emotional experience (Lieberman, Inagaki, Tabibnia, & Crockett, 2011), suggesting that verbally labeling affective responses leads to the incidental regulation of affective responses to them. Self-serving biases. Self-enhancement, or the motivated tendency to judge oneself in an unrealistically positive light, represents another pervasive phenomenon that relates to affect regulation (Taylor & Brown, 1994). Interestingly, the most consistent neural marker of unrealistically positive social cognition seems to be a reduction in vmPFC activity (Hughes & Beer, 2012; Somerville, Kelley, & Heatherton, 2010), which has been interpreted as reflecting reductions in integration processes that can be used to overcome self-serving biases (Beer, 2012). Self-regulation. Given that many domains of regulation rely on similar regions of the brain, recent studies that have attempted to use brain imaging to examine the neural basis of the prominent limited resource model of self-regulation hold that repeated attempts at regulation draw on and eventually exhaust a common regulatory resource (Baumeister & Heatherton, 1996; Heatherton, 2011). Recent imaging work supports this idea by showing that engaging in an effortful selfregulation task leads to exaggerated amygdala responses to negative images and reduced functional connectivity between the amygdala and the vmPFC (Wagner & Heatherton, 2013). Conclusion and Future Directions In this article, we have outlined research demonstrating that the brain mechanisms of emotion regulation involve interactions between emotion generation regions that support emotional responding and domain-general control regions that act to modulate activity in these generation regions. Available research suggests that this model, derived primarily from studies of reappraisal, may generalize to diverse social and emotional contexts, but the particular regions recruited (and the interplay between these regions) are likely to vary across emotion categories, stimulus types, regulatory goals, and specific regulatory tactics. Although research on this topic has expanded dramatically in recent years, several areas merit even closer attention. An important goal for translational research will be to understand how dysfunction in either bottom-up emotion generation or topdown control might underlie patterns of emotional changes observed in psychopathology. Such a direction is already being pursued in studies of emotion regulation across various disorders, including borderline personality disorder (e.g., Koenigsberg et al., 2009), major depression (e.g., Heller et al., 2009), bipolar disorder (e.g., Townsend et al., 2012), and anxiety disorders (e.g., Etkin & Wager, 2007). Similarly, there will be a growing value in research that investigates brain changes underlying life-span changes in emotion experience from childhood and adolescence (e.g., McRae, Ciesielski, & Gross, 2012; Silvers et al., 2012) to young adulthood and old age (e.g., Mather, 2012). In addition to these translational directions, several basic questions about the regulation of emotion remain understudied. First, among the constellation of distinct regions that support reappraisal, the mechanistic contributions of particular regions remain relatively unclear; this could be addressed by applying conjunction analyses to reappraisal and cognitive control tasks and by developing more controlled paradigms that fractionate reappraisal into distinct component processes (see Cohen, Berkman, & Lieberman, 2012). Second, it will be important for future studies to determine the impact of stimulus valence and regulatory goals on activity in control regions and emotion generation regions, as well as intermediary regions that may mediate these effects. Third, it will be important to use neuroscience to address fundamentally new questions about how emotion regulation operates. For example, although theories of emotion regulation emphasize the importance of recognizing appropriate contexts to regulate and activating and sustaining a goal to implement regulation, little is known about the mechanisms underlying these abilities. For another, while it is clear that regulation strategies have large immediate effects on emotional responses, few studies have attempted to determine the long-term effects of practicing regulation on responses to previously regulated or novel stimuli. Lastly, although virtually all of the research on this topic looks at explicit regulation, it will be important to understand the neural mechanisms underlying more implicit or automatic forms of regulation, which may be less prone to failure under certain circumstances. In addressing these and other questions, it is our hope that this field will continue to inspire theoretical and empirical work that builds a nuanced and comprehensive understanding of the contribution of specific brain mechanisms to emotion regulation successes and failures. See also: INTRODUCTION TO SOCIAL COGNITIVE NEUROSCIENCE: Emotional Experience; Self-Regulation and SelfRegulation Failure; INTRODUCTION TO SYSTEMS: Brain Mapping of Control Processes; Emotion; Reward; Salience Network. Brain Mapping: An Encyclopedic Reference, (2015), vol. 3, pp. 53-58 Author's personal copy INTRODUCTION TO SOCIAL COGNITIVE NEUROSCIENCE | Emotion Regulation References Aron, A. R., Robbins, T. W., & Poldrack, R. A. (2004). Inhibition and the right inferior frontal cortex. Trends in Cognitive Sciences, 8(4), 170–177. Augustine, J. R. (1996). Circuitry and functional aspects of the insular lobe in primates including humans. Brain Research Reviews, 22(3), 229–244. Badre, D., & Wagner, A. D. (2007). Left ventrolateral prefrontal cortex and the cognitive control of memory. Neuropsychologia, 45(13), 2883–2901. Barrett, L. F. (2012). Emotions are real. Emotion, 12(3), 413–422. Baumeister, R. F., & Heatherton, T. F. (1996). Self-regulation failure: An overview. Psychological Inquiry, 7(1), 1–15. Beer, J. S. (2012). This time with motivation: The implications of social neuroscience for research on motivated self-and other-perception (and vice versa). Motivation and Emotion, 36(1), 38–45. Binder, J. R., & Desai, R. H. (2011). The neurobiology of semantic memory. Trends in Cognitive Science, 15(11), 527–536. Botvinick, M. M., Braver, T. S., Barch, D. M., Carter, C. S., & Cohen, J. D. (2001). Conflict monitoring and cognitive control. Psychological Review, 108(3), 624. Buhle, J. T., Silvers, J. A., Wager, T. D., Lopez, R., Onyemekwu, C., Kober, H., et al. (2014). Cognitive reappraisal of emotion: A meta-analysis of human neuroimaging studies. Cerebral Cortex, 24, 2981–2990. Chang, L. J., Yarkoni, T., Khaw, M. W., & Sanfey, A. G. (2013). Decoding the role of the insula in human cognition: Functional parcellation and large-scale reverse inference. Cerebral Cortex, 23(3), 739–749. Cloutier, J., Heatherton, T. F., Whalen, P. J., & Kelley, W. M. (2008). Are attractive people rewarding? Sex differences in the neural substrates of facial attractiveness. Journal of Cognitive Neuroscience, 20(6), 941–951. Cohen, J. R., Berkman, E. T., & Lieberman, M. D. (2012). Intentional and incidental selfcontrol in ventrolateral PFC. Principles of Frontal Lobe Functions, 417–440, . Corbetta, M., & Shulman, G. L. (2002). Control of goal-directed and stimulus-driven attention in the brain. Nature Reviews Neuroscience, 3(3), 201–215. Craig, A. D. (2009). How do you feel-now? The anterior insula and human awareness. Nature Reviews Neuroscience, 1, 59–70. Cunningham, W. A., Van Bavel, J. J., & Johnsen, I. R. (2008). Affective flexibility evaluative processing goals shape amygdala activity. Psychological Science, 19(2), 152–160. Delgado, M. R., Gillis, M. M., & Phelps, E. A. (2008). Regulating the expectation of reward via cognitive strategies. Nature Neuroscience, 11(8), 880–881. Denny, B. T., Kober, H., Wager, T. D., & Ochsner, K. N. (2012). A meta-analysis of functional neuroimaging studies of self-and other judgments reveals a spatial gradient for mentalizing in medial prefrontal cortex. Journal of Cognitive Neuroscience, 24(8), 1742–1752. DeSteno, D., Gross, J. J., & Kubzansky, L. (2013). Affective science and health: The importance of emotion and emotion regulation. Health Psychology, 32(5), 474. DeSteno, D., Li, Y., Dickens, L., Lerner, J. S. (2014, in press) Gratitude: A tool for reducing economic impatience. Psychological Science. Diekhof, E. K., Geier, K., Falkai, P., & Gruber, O. (2011). Fear is only as deep as the mind allows: A coordinate-based meta-analysis of neuroimaging studies on the regulation of negative affect. NeuroImage, 58(1), 275–285. Erk, S., Mikschl, A., Stier, S., Ciaramidaro, A., Gapp, V., Weber, B., et al. (2010). Acute and sustained effects of cognitive emotion regulation in major depression. The Journal of Neuroscience, 30(47), 15726–15734. Etkin, A., & Wager, T. D. (2007). Functional neuroimaging of anxiety: A meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. The American Journal of Psychiatry, 164(10), 1476. Fehr, E., & Rangel, A. (2011). Neuroeconomic foundations of economic choice: Recent advances. The Journal of Economic Perspectives, 25(4), 3–30. Garfinkel, S. N., Barrett, A. B., Minati, L., Dolan, R. J., Seth, A. K., & Critchley, H. D. (2013). What the heart forgets: Cardiac timing influences memory for words and is modulated by metacognition and interoceptive sensitivity. Psychophysiology, 50, 505–512. Garfinkel, S. N., & Critchley, H. D. (2013). Interoception, emotion and brain: new insights link internal physiology to social behaviour. Commentary on: “Anterior insular cortex mediates bodily sensibility and social anxiety” by Terasawa et al. (2012). Social Cognitive and Affective Neuroscience, 8(3), 231–234. Gross, J. J., & Mun˜oz, R. F. (1995). Emotion regulation and mental health. Clinical Psychology: Science and Practice, 2(2), 151–164. Gross, J. J. (1998). The emerging field of emotion regulation: An integrative review. Review of General Psychology, 2(3), 271. Gross, J. J., & John, O. P. (2003). Individual differences in two emotion regulation processes: Implications for affect, relationships, and well-being. Journal of Personality and Social Psychology, 85(2), 348. 57 Gyurak, A., Gross, J. J., & Etkin, A. (2011). Explicit and implicit emotion regulation: A dual-process framework. Cognition and Emotion, 25(3), 400–412. Haber, S. N., & Knutson, B. (2009). The reward circuit: Linking primate anatomy and human imaging. Neuropsychopharmacology, 35(1), 4–26. Heatherton, T. F. (2011). Neuroscience of self and self-regulation. Annual Review of Psychology, 62, 363. Heller, A. S., Johnstone, T., Shackman, A. J., Light, S. N., Peterson, M. J., Kolden, G. G., et al. (2009). Reduced capacity to sustain positive emotion in major depression reflects diminished maintenance of fronto-striatal brain activation. Proceedings of the National Academy of Sciences, 106(52), 22445–22450. Hsieh, F., Ferrer, E., Chen, S., Mauss, I. B., John, O., & Gross, J. J. (2011). A network approach for evaluating coherence in multivariate systems: An application to psychophysiological emotion data. Psychometrika, 76(1), 124–152. Hughes, B. L., & Beer, J. S. (2012). Orbitofrontal cortex and anterior cingulate cortex are modulated by motivated social cognition. Cerebral Cortex, 22(6), 1372–1381. Johnstone, T., van Reekum, C. M., Urry, H. L., Kalin, N. H., & Davidson, R. J. (2007). Failure to regulate: Counterproductive recruitment of top-down prefrontalsubcortical circuitry in major depression. The Journal of Neuroscience, 27(33), 8877–8884. Kalisch, R. (2009). The functional neuroanatomy of reappraisal: Time matters. Neuroscience & Biobehavioral Reviews, 33(8), 1215–1226. King-Casas, B., Tomlin, D., Anen, C., Camerer, C. F., Quartz, S. R., & Montague, P. R. (2005). Getting to know you: Reputation and trust in a two-person economic exchange. Science, 308(5718), 78–83. Kober, H., Barrett, L. F., Joseph, J., Bliss-Moreau, E., Lindquist, K., & Wager, T. D. (2008). Functional grouping and cortical–subcortical interactions in emotion: A meta-analysis of neuroimaging studies. NeuroImage, 42(2), 998–1031. Kober, H., Mende-Siedlecki, P., Kross, E. F., Weber, J., Mischel, W., Hart, C. L., et al. (2010). Prefrontal–striatal pathway underlies cognitive regulation of craving. Proceedings of the National Academy of Sciences, 107(33), 14811–14816. Koenigsberg, H. W., Fan, J., Ochsner, K. N., Liu, X., Guise, K. G., Pizzarello, S., et al. (2009). Neural correlates of the use of psychological distancing to regulate responses to negative social cues: A study of patients with borderline personality disorder. Biological Psychiatry, 66(9), 854–863. Kross, E., & Ayduk, O. (2008). Facilitating adaptive emotional analysis: Distinguishing distanced-analysis of depressive experiences from immersed-analysis and distraction. Personality and Social Psychology Bulletin, 34(7), 924–938. Lazarus, R. S. (1991). Emotion and adaptation. Oxford: University Press. LeDoux, J. (1998). Fear and the brain: Where have we been, and where are we going? Biological Psychiatry, 44(12), 1229–1238. Levy, B. J., & Wagner, A. D. (2011). Cognitive control and right ventrolateral prefrontal cortex: Reflexive reorienting, motor inhibition, and action updating. Annals of the New York Academy of Sciences, 1224(1), 40–62. Lieberman, M. D., Inagaki, T. K., Tabibnia, G., & Crockett, M. J. (2011). Subjective responses to emotional stimuli during labeling, reappraisal, and distraction. Emotion, 11(3), 468. Mather, M. (2012). The emotion paradox in the aging brain. Annals of the New York Academy of Sciences, 1251(1), 33–49. Mauss, I. B., Levenson, R. W., McCarter, L., Wilhelm, F. H., & Gross, J. J. (2005). The tie that binds? Coherence among emotion experience, behavior, and physiology. Emotion (Washington, D. C.), 5(2), 175. Chicago. McRae, K., Ciesielski, B., & Gross, J. J. (2012). Unpacking cognitive reappraisal: Goals, tactics, and outcomes. Emotion, 12(2), 250–255. Miller, E. K., & Cohen, J. D. (2001). An integrative theory of prefrontal cortex function. Annual Review of Neuroscience, 24(1), 167–202. Mitchell, J. P. (2009). Social psychology as a natural kind. Trends in Cognitive Sciences, 13(6), 246–251. O’Doherty, J. P. (2004). Reward representations and reward-related learning in the human brain: Insights from neuroimaging. Current Opinion in Neurobiology, 14(6), 769–776. Ochsner, K. N., Silvers, J. A., & Buhle, J. T. (2012). Functional imaging studies of emotion regulation: A synthetic review and evolving model of the cognitive control of emotion. Annals of the New York Academy of Sciences, 1251, E1–E24. Phelps, E. A. (2006). Emotion and cognition: Insights from studies of the human amygdala. Annual Review of Psychology, 57, 27–53. Ptak, R. (2012). The frontoparietal attention network of the human brain action, saliency, and a priority map of the environment. The Neuroscientist, 18(5), 502–515. Richards, J. M., & Gross, J. J. (2000). Emotion regulation and memory: The cognitive costs of keeping one’s cool. Journal of Personality and Social Psychology, 79(3), 410. Brain Mapping: An Encyclopedic Reference, (2015), vol. 3, pp. 53-58 Author's personal copy 58 INTRODUCTION TO SOCIAL COGNITIVE NEUROSCIENCE | Emotion Regulation Ridderinkhof, K. R., Ullsperger, M., Crone, E. A., & Nieuwenhuis, S. (2004). The role of the medial frontal cortex in cognitive control. Science, 306(5695), 443–447. Roy, M., Shohamy, D., & Wager, T. D. (2012). Ventromedial prefrontal-subcortical systems and the generation of affective meaning. Trends in Cognitive Sciences, 16(3), 147–156. Salimpoor, V. N., Benovoy, M., Larcher, K., Dagher, A., & Zatorre, R. J. (2011). Anatomically distinct dopamine release during anticipation and experience of peak emotion to music. Nature Neuroscience, 14(2), 257–262. Schiller, D., & Delgado, M. R. (2010). Overlapping neural systems mediating extinction, reversal and regulation of fear. Trends in Cognitive Sciences, 14(6), 268–276. Schoenbaum, G., Saddoris, M. P., & Stalnaker, T. A. (2007). Reconciling the roles of orbitofrontal cortex in reversal learning and the encoding of outcome expectancies. Annals of the New York Academy of Sciences, 1121(1), 320–335. Schultz, W., Dayan, P., & Montague, P. R. (1997). A neural substrate of prediction and reward. Science, 275(5306), 1593–1599. Silvers, J. A., McRae, K., Gabrieli, J. D., Gross, J. J., Remy, K. A., & Ochsner, K. N. (2012). Age-related differences in emotional reactivity, regulation, and rejection sensitivity in adolescence. Emotion, 12(6), 1235–1247. Snyder, H. R., Hutchison, N., Nyhus, E., Curran, T., Banich, M. T., O’Reilly, R. C., et al. (2010). Neural inhibition enables selection during language processing. Proceedings of the National Academy of Sciences, 107(38), 16483–16488. Somerville, L. H., Kelley, W. M., & Heatherton, T. F. (2010). Self-esteem modulates medial prefrontal cortical responses to evaluative social feedback. Cerebral Cortex, 20(12), 3005–3013. Taylor, S. E., & Brown, J. D. (1994). Positive illusions and well-being revisited: Separating fact from fiction. Psychological Bulletin, 116(1), 21–27. Torrisi, S. J., Lieberman, M. D., Bookheimer, S. Y., & Altshuler, L. L. (2013). Advancing understanding of affect labeling with dynamic causal modeling. NeuroImage, 82, 481–488. Townsend, J. D., Torrisi, S. J., Lieberman, M. D., Sugar, C. A., Bookheimer, S. Y., & Altshuler, L. L. (2012). Frontal-amygdala connectivity alterations during emotion downregulation in bipolar I disorder. Biological Psychiatry, 73(2), 127–135. Visser, M., & Ralph, M. L. (2011). Differential contributions of bilateral ventral anterior temporal lobe and left anterior superior temporal gyrus to semantic processes. Journal of Cognitive Neuroscience, 23(10), 3121–3131. Wager, T. D., Davidson, M. L., Hughes, B. L., Lindquist, M. A., & Ochsner, K. N. (2008). Prefrontal-subcortical pathways mediating successful emotion regulation. Neuron, 59(6), 1037–1050. Wager, T. D., Jonides, J., & Reading, S. (2004). Neuroimaging studies of shifting attention: A meta-analysis. NeuroImage, 22(4), 1679–1693. Wager, T. D., & Smith, E. E. (2003). Neuroimaging studies of working memory: A meta-analysis. Cognitive, Affective, & Behavioral Neuroscience, 3(4), 255–274. Wagner, D. D., & Heatherton, T. F. (2013). Self-regulatory depletion increases emotional reactivity in the amygdala. Social Cognitive and Affective Neuroscience, 8(4), 410–417. Whalen, P. J. (1998). Fear, vigilance, and ambiguity: Initial neuroimaging studies of the human amygdala. Current Directions in Psychological Science, 7(6), 177–188. Zaki, J., Davis, J. I., & Ochsner, K. N. (2012). Overlapping activity in anterior insula during interoception and emotional experience. NeuroImage, 62(1), 493–499. Brain Mapping: An Encyclopedic Reference, (2015), vol. 3, pp. 53-58
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