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Drug Delivery Systems:
From Drug-Discovery, Pre-formulation, Formulation and Technological Approaches for
Poorly Soluble Drugs and Protein
L4-L5 November 2OL4
PULLMAN Surabaya City Centre
ORGANIZING COMMITEE
Advisor
Chair Person
Vice Chair Person
: Dean of Faculty of pharmacy Universitas Airlangga
: Dra. Esti Hendradi, M.Si., ph.D, Apt.
: Helmy yusuf, M.Sc., ph.D, Apt.
Scientific Committee:
Prof. Dr. Widjisoeratri, DEA, Apt.
Prof. Dr. Siswandono, M.S.,Apt.
Prof .Dr. Tutuk Budiarti, M.S.,Apt.
Prof. Dr. rer.nat. Muhammad yuwono, M.S.,Apt.
Dr. Achmad Radjaram, Apt.
Drs. Hadi Purwono, ph.D, Apt.
Drs. Marcellino Rudyanto, M.Si., ph.D Apt.
Dr. Juni Ekowati, M.Si, Apt.
Dr. DwiSetyawan, M.Si, Apt.
Helmy Yusuf, M.Sc., ph.D, Apt.
Social Programme:
Drs. Bambang Widjaja, M.Si, Apt.
Dra. Retno Sari, M.Sc,
Apt.
Dr. Riesta Primahastinastiti, M.Si, Apt.
Maria Lucia Ardhani, ph.D, Apt.
Melanny Sulistyowati, M.Sc, Apt.
Secretariat :
Dewi Melani Hariyadi, M.phil., ph.D, Apt.
Febri Annuryanti, M.Sc, Apt.
M. Faris Adrianto, M.Farm, Apt.
Dra. Tutiek Purwanti, M.Si, Apt.
Dra. Tristiana Erawati, M.Si, Apt.
Abhimata P, S.Farm, Apt.
Saadun
Treasury:
Dra. Noorma Rosita, M.Si, Apt.
Dra. Dewi lsadiartuti, M.Si, Apt.
Exhibition
:
Drs. Sugiyartono, M.Si, Apt.
Drs. A. Toto Poernomo, M.Si, Apt.
I
nformation Technology Team
Deddy, Sfarm.
,
P-76
Sitvia Dwi Damavanti
P-77
Sreedharan Nair
P-78
Sudheer Moorkoth-P
P-79
Susiyartono
P-80
Suko Hardiono
Anioxidant and AntimicrobiaI Activities of The Extracts ol
Abetmoschus manihot, L. Medik Leaves
Systemic Lupus Erythematosus: CtinicaI manifestations, treatment
patterns and outcome
Devetopment of a Stabitity lndicating RP-HPLC Method Compatibl.e
with LC-MS/MS for Effaverinz
lnftuence of EMCOMPRESS Concentration on The Physicat Properties
ofTablet Containine Lactobaciltus soo. And Guava Leaves Extract
Efforts to Produce 1-(BenzoyLoxy)Urea As Anticancer Candidate
The lnfluence of Hydroxy Group of Ortho (o) And Para (p) Positions
on Methytbenzoate Against Synthesis of Hydroxybenzohidrazide
Derivatives
ln Vitro Anticandidiasis Activity of Citronelta Herb (Cymbopogon
P-81
Suzana
P-82
Svarmatina
P-83
Titiek Martati-P
P-84
Tutiek Purwanti
NiosomaI Svstem Usins Soan 20 and Soan 60
Formutation and Characterization of Juice of Lime Ge[ Using CMC-Na
P-85
[Jswatun Chasanah-P
P-86
Va[entina Yurina
Base
Nigel.l.a Sative Extract Reduce RenaL NOX4 Level of Diabetic Type 2
Wistar Rats Model
P-87
Vasantharaiu 5 G-P
P-88
Vasudev Pai-P
P-89
Vijayanarayana
Kunhikatta
P-90
Vina Atvionita Soesilo
P-91
Wimzv Rizov
P-92
Wiwin Herdwiani
P-93
Ros Sumarny
P-94
Yola Desnera Putri
P-95
Yuli Ainun Naiih
P
nardus L.)
Antioxidant Activity Test of Bee Propotis Extract (Apis metlifera L.)
Using DPPH (1,1-diphenyt-2-pikrithidarzit) Free Radicats Scavenging
Activity
Physicat Characteristics and Penetration of Diclofenac Sodium
BioanatyticaI method deve[opment and vatidation of AminophyLLine
in rat plasma using RP-HPLC - An application to preclinica[
oha rmacok inetics
ln-vitro anti-oxidant and acetytcho[inesterase inhibition assay of
Punica sranatum (oeel) and Gmelina arborea (bark) extracts
ldentification of risk factors associated with mortatity and
deve[opment of mortatity prediction mode[ for hospitat-acquired
nner r mon ia
Hepatoprotective Activity of Bidens pitosa
L.
on Rat
Cytotoxic Activity Assay Against Hela Cet[ Lines of Novel Anticancer
Drus: N-(Phenyl.Carbamoy[) lsobutiramide
Cytotoxic Effect of ALL The Part Cinnamon Ptant to WiDr Cett Line fot
Getting a MedicinaI P[ants as PotentiaI Chemoprevention of
ColorectaI Cancer
Antioxidant Study of Cosotvent So[ution of Mangosteen (Garcinia
mansostana L.) Rind Extract in Rats bv Usine MDA Parameter
Formulation Of Shower Ge[ as An Antiseptic From Ethyl Acetate
Fraction of Mansosteen's Rind (Garcinia mangostana L.)
Kinetics Study Cocrystatd Ketokonazo[e-Succinic Acid Prepared With
Slurry Method Based on Powder X.Ray Diffraction(PXRD)
Construction of Recombinant lmmunotoxin Anti-EGFRvl I SCFV::HPR
Fusion Protein and lnducib[e Expression in Pichia Pastoris as A
Tareeted Drue Candidate
lnu[in Determination of Yam Bean Tuber (PACYRRHIZUS EROSUS L.)
From Different Al.titude Areas usinp TLC Densitometrv
OraI Antidiabetic Drug Prescribing Profi[es ln SeveraI Pharmacies
Located ln West Reeion of Surabava
The Potency Of Canarium Oi[ (Canarium lndicum) As A Materia[ For
Structured Lioid Production
I
P-96
Yutiawati Adireia
P-97
Yuni Retnaninstyas
P-98
Yunita Nita
Hamidah Rahman
FORMULATION AND CHARACTERIZAIION OF JUICE OF ttME GEt USING CMC-Na BASE
Uswatun Chasanah*, lnayah*, Esti Hendradi**
* University of Muhammadiyah Malang, ** Airlangga University
u.chaso
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Lime (Citrus ourantifoliol is one of the plants that are used as cosmetics. The juice of lime
contained citric acid that acts as an antioxidant. This study was conducted to determine the
concentration of juice of lime on gel formulated with CMC-Na base that has the best of
physical characteristics, pH, release of acid citric from gel preparations and acceptability. The
evaluations were included organoleptic, viscosity, pH and release of acid citric from gel base.
The result of organoleptic observations on the gel of juice of lime, gel with dosage levels of
LOyo,2oyo,and3O%o,all have softtexture and clear; the lemon smellthat sharper is a gelofjuice
of lime dosage levels of 3O%; and the more concentration of the juice of lime, then, more
yellow in color. Result of One-Way Anova test analysis for viscosity gel showed that the goal of
juice of lime with dosage level of 30% has a higher viscosity. Meanwhile, the outcome of the
test release of citric acid from gel base, of all three levels is no dissimilar. Acceptability for all
forpulas were above 63%. For ease of flattelled and cold sensation, the highest is the goal of
juice of lime dosage level of 30%, meanwhile easy to clean is the goal of juice of lime dosage
level of 2O%. Based on the result, the best formula is a gel of juice of lime with dosage levels of
30%.
Keywords:, juice of lime (Citrus aurantifotial, gel, CMC-Na