Neural Prosthetic Engineering (3 Credits) 神经假体工程 Instructor Sung June KIM ([email protected]), Dept of Electrical & Computer Engineering, Seoul National University , Seoul Korea Synopsis The aim of this course is to understand the principles and state-of-the arts development of the Neural Prosthesis. Neural prosthesis is an electronic implant that interfaces with nervous systems. Through direct electrical stimulation of nerves, it can help restore damaged or lost sensory or motion functions. Typical examples include cochlear implant and retina implant recently developed for severely hearing and vision impaired patients respectively. More recently interfacing with neurons in brain draws more attention for both therapeutic and scientific purposes. In this lecture we will cover all engineering aspects of the auditory, visual prostheses, and deep brain stimulation. Offering 2015 Julmester Audience All levels of Engineering Students (Some basic electrical circuits will be taught during the class.) Classroom Room xxx, Teaching Bldg. No. XX, Peking University Schedule Class: 2-5 PM, M-F, July 6–24, 2015; Final Exam: 2-5 PM, July 25, 2015 Objective To understand fundamentals of neural prosthetic engineering and their application in auditory, visual prostheses and deep brain stimulation. Topics 1. Introduction: A gentle introduction to neural prostheses and their history 2. Fundamental 1 – At the metal electrode (electrochemistry, charge storage and impedance) 3. Fundamental 2 – Electronics (circuit and biotelemetry) 4. Fundamental 3 – Neurophysiology and biopotentials 5. Fundamental 4 – The implant technology (biomaterials, biocompatibility, the electrode and the hermetic package) 6. Application 1 – Cochlear implant 7. Application 2 – Visual prosthesis 8. Application 3 – Deep brain stimulation 9. Application 4 – Regulator approval of implantable medical devices 10. Application 5 – Future prospects 11. Term project presentation References 1. D. Zhou, David and E. Greenbaum, eds. Implantable Neural Prostheses 1: Devices and Applications, Springer, 2009. 2. D. R. Merrill, "The electrochemistry of charge injection at the electrode/tissue interface," in Implantable Neural Prostheses 2, ed: Springer, 2010, pp. 85-138. 3. P. Troyk and S. Cogan, "Sensory Neural Prostheses," in Neural Engineering, B. He, Ed., ed: Springer US, 2005, pp. 1-48. 4. G. Loeb, "We Made the Deaf Hear. Now What?," in Toward Replacement Parts for the Brain, MIT Press, 2005. 5. Other journal papers Grading Midterm Exam 20% Final Exam 20% Homework 20% Term Project 20% Attendance 20% Total 100%