Renal Cell Carcinoma BY THE NUMBERS Renal cell carcinoma, or RCC, is the most common type of kidney cancer. It typically starts in the lining of small tubes in the kidney. RCC usually forms as a single tumor but more than one tumor may grow in one or both kidneys. Kidney Cancer Prevalence ESTIMATED 2012 CASES Kidney cancer is the 13th most common cancer worldwide with ~338,000 new cases diagnosed in 2012. Less than 50,000 50,000100,000 100,001150,000 EUROPE 115,252 cases NORTH AMERICA 63,822 cases ASIA 123,402 cases AFRICA 10,033 cases CENTRAL AMERICA 4,492 cases SOUTH AMERICA 15,661 cases OCEANIA 4,168 cases Subtypes of RCC Clear cell RCC: 75% 9 of 10 Papillary RCC: 10% Chromophobe RCC: 5% kidney cancers are RCC. There are several subtypes of RCC, including: Other Rare and Unclassified Subtypes: 10% Family history Smoking Risk factors While the cause of RCC is unknown, several risk factors exist which may increase a person’s likelihood of developing the disease Obesity High blood pressure Asbestos exposure Signs and Symptoms of RCC Early-stage RCC is not typically associated with any signs or symptoms. However, patients with larger tumors might experience some of the following: • Blood in the urine • Weight loss not caused by dieting • Tiredness • A mass lump • Low red blood and/or pain on the • Fever that is not cell counts side or lower back caused by an infection and does • Loss of appetite not go away While research is ongoing, there are many resources available to help patients with RCC learn more about the disease and find clinical trials, including: For more information, please visit ImmunoOncologyNow.com © 2015 Bristol-Myers Squibb Company ONCUS15UB00045-01-01 03/15