Genetics Questions: Monohybrid + Dihybrid Crosses
STEP 1: Determine what kind of problem you are trying to solve.
STEP 2: Determine letters you will use to specify traits.
STEP 3: Determine parent’s genotypes.
STEP 4: Make your Punnett square and make gametes
STEP 5: Complete cross and determine possible offspring.
STEP 6: Determine genotypic and phenotypic ratios.
Monohybrid Crosses
1. In minks, brown is dominant over silver-blue color. What offspring would you predict if you
crossed a homozygous brown mink with a silver-blue mink?
2. What would the genotypic and phenotypic ratios of two F2 generation mink from the above
problem be if they were crossed?
3. In humans, acondroplasia “dwarfism” (D) is dominant over normal (d). A homozygous dominant
(DD) person dies before the age of one. A heterozygous (Dd) person is dwarfed. A homozygous
recessive individual is normal. A heterozygous dwarf man marries a dwarf heterozygous woman.
Give the genotypic and phenotypic ratios of the offspring
4. In humans, free earlobes (F) are dominant over attached earlobes (f). If one parent is
homozygous dominant for free earlobes, while the other has attached earlobes can they
produce any children with attached earlobes?
5. In humans widow’s peak (W) is dominant over straight hairline (w). A heterozygous man for this
trait marries a woman who is also heterozygous. Give the genotypic and phenotypic ratios of the
offspring.
6. In pea plants, yellow seeds (Y) are dominant and green seeds (y) are recessive. In another cross,
a yellow seeded plant was crossed with another yellow seeded plant and it produced offspring
of which about 25% were green seeded plants. What are the genotypes of both parents?
Dihybrid Crosses
7. In horses, black is dependent upon a dominant gene, B, and chestnut upon its recessive allele, b.
The trotting gait is due to a dominant gene, T, the pacing gait to its recessive allele, t. If a
homozygous black pacer is mated to a homozygous chestnut trotter, what will be the
appearance of the F1 generation?
8. In mice, the ability to run normally i s a dominant trait. Mice with this trait are called running
mice (R). The recessive trait causes mice to run in circles only. Mice with this trait are called
waltzing mice (r). Hair color is also inherited in mice. Black hair (B) is dominant over brown hair
(b).
For each of the following problems, determine:
–
parent genotypes
–
possible gametes
–
construct a Punnett square
–
provide the offspring phenotypic ratio.
a. Cross a heterozygous running, heterozygous black mouse with a homozygous running,
homozygous black mouse
b. Cross a homozygous running, homozygous black mouse with a heterozygous running,
brown mouse
c. Cross a waltzing brown mouse with a waltzing brown mouse
d. Cross a homozygous running, heterozygous black mouse with a waltzing brown mouse
e. Cross a heterozygous running, brown mouse with a heterozygous running, homozygous
black mouse
f.
Cross a heterozygous running, heterozygous black mouse with a heterozygous running,
heterozygous black mouse