GENOME PRIVACY AT EPFL, LAUSANNE
GENOME PRIVACY AT EPFL, LAUSANNE http://lca.epfl.ch/projects/genomic-privacy/ Genomics is becoming the next significant challenge for privacy [1,3,4]. The price of a complete genome profile has plummeted below $100 for genome-wide genotyping (i.e., the characterization of about one million common genetic variants), which is offered by a number of companies. This low cost of DNA sequencing will break the physician/patient connection and it can open the door to all kinds of abuse, not yet fully understood. Access to genomic data prompts some important privacy concerns: (i) genetic diseases can be unveiled, (ii) the propensity to develop specific diseases (such as Alzheimer's) can be revealed, (iii) a volunteer accepting de facto to have his genomic code made public can leak substantial information about genomic data of his relatives (possibly against their will), and (iv) complex privacy issues can arise if DNA analysis is used for criminal investigations and insurance purposes. Such issues could lead to abuse, threats, and genetic discrimination. At EPFL School of Computer and Communication Sciences, we have been working on different aspects of genome privacy in strong collaborations with genomic researchers and medical doctors. In particular, we focus on the following main research directions: Protecting and Evaluating Genome Privacy in Medical Tests and Personalized Medicine [5,7,8,9,11,13]. Privacy-Preserving Processing of Raw Genomic Data [11]. Quantification and Protection of Kin Genomic Privacy [2,6,10]. Collaborators: Contact: University Hospital in Lausanne (CHUV), Sophia Genetics, EPFL School of Life Sciences, University of Waterloo, University College London, University of California Irvine, University of Illinois at UrbanaChampaign, Indiana University Bloomington, Vanderbilt University, Cornell Tech. Dr. Huang Lin Prof. Jean-Pierre Hubaux [email protected] [email protected] Dr. Paul J. McLaren Prof. Jacques Fellay [email protected] [email protected] [1] Z. Huang, E. Ayday, J. Fellay, J.-P. Hubaux, and A. Juels, “GenoGuard: Protecting Genomic Data against Brute-Force Attacks”, 36th IEEE Symposium on Security and Privacy (S&P 2015), San Jose, CA, USA, May 2015. [2] M. Humbert, E. Ayday, J.-P. Hubaux, and A. Telenti, "On Non-cooperative Genomic Privacy", 19th International Conference on Financial Cryptography and Data Security (FC), 2015. [3] E. Ayday, E. D. Cristofaro, J.-P. Hubaux, and G. Tsudik, "Whole Genome Sequencing: Revolutionary Medicine or Privacy Nightmare?", Computer, vol.48, no. 2, pp. 58-66, Feb. 2015, doi:10.1109/MC.2015.59. [4] M. Naveed, E. Ayday, E. W. Clayton, J. Fellay, C. A. Gunter, J.-P. Hubaux, B. A. Malin, and X. Wang, “Privacy and Security in the Genomic Era”, arXiv: 1405.1891, 2014. [5] A. Telenti, E. Ayday, and J.-P.Hubaux, “On Genomics, Kin, and Privacy”, F1000Research 2014, 3:80 (doi: 10.12688/f1000research.4089). [6] J.L. Reisaro, E. Ayday, and J.-P.Hubaux, “Patient Privacy in the Genomic Era”, Praxis, 7 May 2014 [7] E. Ayday, E. De Cristofaro, G. Tsudik, and J. P. Hubaux, “The Chills and Thrills of Whole Genome Sequencing,” arXiv:1306.1264, 2013. [8] M. Naveed, S. Agrawal, M. Prabhakaran, X. Wang, E. Ayday, J.-P. Hubaux and C.A. Gunter, “Controlled Functional Encryption,” In proceedings of 21st ACM Conference on Computer and Communications Security (CCS 2014), Scottsdale, AZ, USA, Nov. 2014. [9] M. Humbert, E. Ayday, A. Telenti, and J. P. Hubaux, “Reconciling Utility with Privacy in Genomics,” In Proceedings of ACM Workshop on Privacy in the Electronic Society (WPES), Scottsdale, AZ, USA, Nov. 2014. [10] J.L. Raisaro, E. Ayday, P.J. McLaren, J-P. Hubaux, and A. Telenti, “Privacy-Preserving HIV Pharmacogenetics: A Real Use Case of Genomic Data Protection,” In Workshop on Genome Privacy (in conjunction with PETS 2014), Amsterdam, Netherlands, July 2014. [11] E. Ayday, J. L. Raisaro, J. Rougemont, and J. P. Hubaux, “Protecting and Evaluating Genomic Privacy in Medical Tests and Personalized Medicine,” In Proceedings of ACM Workshop on Privacy in the Electronic Society (WPES), Berlin, Germany, Nov. 2013. [12] M. Humbert, E. Ayday, A. Telenti, and J. P. Hubaux, “Addressing the Concerns of the Lacks Family: Quantification of Kin Genomic Privacy,” In Proceedings of 20th ACM Conference on Computer and Communications Security (CCS 2013), Berlin, Germany, November 2013. [13] E. Ayday, J. L. Raisaro, U. Hengartner, A. Molyneaux, and J. P. Hubaux, “Privacy-Preserving Processing of Raw Genomic Data,” In Proceedings of 8th Data Privacy Management (DPM 2013) International Workshop (in conjunction with ESORICS 2013), Egham, UK, September 2013. [14] E. Ayday, J. L. Raisaro, P.J. McLaren, J. Fellay, and J.-P. Hubaux, “Privacy-Preserving Computation of Disease Risk by Using Genomic, Clinical, and Environmental Data,” In proceedings of USENIX Security Workshop on Health Information Technologies (HealthTech '13), Washington, DC, USA, August, 2013. [15] E. Ayday, J.L. Raisaro, and J.P. Hubaux, “Privacy-Enhancing Technologies for Medical Tests Using Genomic Data (short paper),” In 20th Annual Network & Distributed System Security Symposium – NDSS 2013, San Diego, CA, USA, February, 2013.
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