RADIOLOGIC ANATOMY OF THE BRAIN Assistant professor Dr. Haider Najim Aubaid F.B.M.S., D.M.R.D 1 MRI Vs CT Brain CT… You have to recognize the following: 1. Cerebral hemispheres 2. Basal ganglia and thalamus 3. Meningies 4. Brainstem 5. cerebellum 6. Ventricular system 7. Basal cisterns (subarachnoid space) 4 -The Sylvain cistern and fissure separating the frontal and temporal lobes are easily identified on axial CT or MR slices -The central sulcus •between the frontal and parietal lobes. •less well seen, lies just posterior to the anterior limit of the lateral ventricles. •on upper images the central sulcus is quite posterior in position. The parieto-occipital sulcus on the medial surface of the hemisphere can be seen on CT at the level of the lateral ventricles and on midline sagittal MR images The parieto-occipital junction on the lateral surface has no anatomical landmark but lies at approximately the same level as the sulcus. Midline sagittal images also show the cingulate gyrus and callosal and cingulate sulci. Insula •This is the cortex buried in the floor of the lateral sulcus. •The parts of the frontal, parietal and temporal lobes that overlie the insula are called the operculum Corona radiata & Centrum semiovale Axial cross-sections of the brain, above the corpus callosum, show a mass of WM on each hemisphere referred to as "centrum semiovale". Below it, projection fibers arising from the cortex and directed towards the internal capsule, together with fibers ascending from below towards the cortex, form the "corona radiata“ within space on each side of the bodies of the lateral ventricles Basal ganglia oThe corpus striatum – othe caudate and olentiform nuclei oThe amygdaloid body; and oThe claustrum. Caudate nucleus •head, body and tail. •It is curved and lies within the concavity of the lateral ventricle. Thus : •head projects into the floor of the anterior (frontal horn) •body lies along the body of the lateral ventricle. •tail lies in the roof of the inferior (temporal) horn. Note: •The head of the caudate nucleus is usually more radiodense than the lentiform nucleus or the thalamus Lentiform nucleus •biconcave lens. •Larger lateral putamen •smaller medial globus pallidus. •Medially, it is separated from the •head of the caudate nucleus anteriorly, •thalamus posteriorly by the internal capsule Claustrum •thin sheet of grey matter lies between the putamen and the insula. •separated medially from the putamen by the external capsule and •bounded laterally by (the extreme capsule) just deep to the insula 20 The corpus callosum •large midline mass of commissural fibers, which connects corresponding areas of both hemispheres. •It is approximately 10 cm long and becomes progressively thicker towards its posterior end. NOTE: •The corpus callosum cannot be well seen on axial CT slices. •The rostrum, genu, body and splenium can be seen on sagittal MRI •Named parts include the: • Rostrum - this is the first part, • Genu - most anterior part; • Trunk (body) -. lies below the lower free edge of the falx cerebri. • Splenium - thickened posterior end. Meningies Pineal gland The pineal gland lies between the posterior ends of the thalami , below splenium above and the superior colliculi. within 3 mm of the midline. Calcification…normal?...abnormal? -measuring • 5–6 mm in length, • 3–6 mm in width and • 3–5 mm in height It does not have a blood–brain barrier and therefore normally enhances after IV contrast. Hypothalamus forms the floor of the 3rd vent. Best be appreciated on midline sagittal MRI It includes the following, starting anteriorly: Optic chiasm; Tuber cinereum - a sheet of grey matter Infundibular stalk - leading down to the posterior lobe of the pituitary gland; Mamillary bodies - small round masses Posterior perforated substance. LEFT: Normal infundibular recess of the third ventricle (blue arrow) , mamillary bodies (red arrow) RIGHT: Tuber cinereum hamartoma (curved arrow PITUITARY GLAND Relations : • Above: the diaphragma sella (dura mater) and above this the suprasellar cistern with the optic chiasm anteriorly and the circle of Willis; • Below: the body of sphenoid and the sphenoid sinus; and • Laterally: the dura and the cavernous sinus and its contents, (ICA and abducent n.) with oculomotor, ophthalmic and trochlear nerves in its walls. Intercavernous sinuses, surround the pituitary gland anteriorly, posteriorly and inferiorly. Notes -Pituitary has high signal intensity on unenhanced T1 W images. -The dura above the sella should be horizontal, not convex? Exceptions?. -The diameter of the infundibulum ..?? THE BRAINSTEM Midbrain Cisterns: 1-Interpeduncular cistern (5) lies anteriorly between cerebral peduncles. 2-Qaderigeminal cistern: (4) lies posterior to quadrigeminal plate Posterior surface of the midbrain presents four rounded prominences - the superior and inferior colliculi (qadri-) Part of the midbrain posterior to the aqueduct is called the tectum or quadrigeminal plate. 5 4 Midbrain Nerves: The third (III oculomotor) N. emerges from between the cerebral peduncles anteriorly The fourth (IV trochlear) N. emerges from the dorsal surface It is not always possible to identify the cerebral aqueduct. Pons the widest part of the brainstem. Basilar artery may be seen anterior to the pons, position to the right or left of the midline is not abnormal. Pons Cranial nerves: Fifth (V facial) N. emerges from the anterolateral surface The sixth (VI abducent) N.: junction with the medulla, close to the midline anteriorly. The seventh and eighth (VII and VIII) cranial nerves : junction with the medulla laterally, that is, (at the CPA) Medulla oblongata Cranial nerves: Ninth and tenth (IX and X glossopharyngeal & vagus) s: posterior to the olive. Eleventh (XI) accessory N. has medullary rootlets that arise inferior to those of X. (note: cervical rootlets arise from the upper spinal cord and enter the foramen magnum to unite with the medullary roots). Twelfth (XII hypoglossal) cranial nerve :anterior to the olive . CEREBELLUM -two hemispheres with the midline vermis between -has a cortex of grey matter and deeper white matter. -The surface of the cerebellum has sulci & folia. Coronal Axial -There are deep nuclei within the hemispheres, the largest of is the dentate nucleus. -Tonsils are the most anterior inferior part of and lie close to the midline. the hemispheres -Three cerebellar peduncles: 1-superior midbrain 2-middle Pons 3- inferior Medulla oblongata The superior surface of the cerebellum slopes upwards from posterior to anterior CT slice of upper cerebellum, contains cerebellum anteriorly and occipital lobes posterolaterally.. Vermis is the narrow midline portion of the cerebellum. Lingula, is the most anterior part of the superior vermis (lying on the superior medullary velum). Nodule, the most inferior part of the vermis Superior vermis can be seen between the occipital lobes on sections through the thalamus VENTRICLES, CISTERNS The ventricles are lined with ependyma, which is invaginated by plexuses of blood vessels called the choroid plexus. These vessels produce the CSF. The ventricular system is continuous with the central canal of the cord & also with the subarachnoid space around the brain via foramina in the fourth ventricle CSF circulation The lateral ventricles Each is C-shaped, with the limbs of the C facing anteriorly and a posterior extension from its midpoint. Each one has a frontal (anterior) horn, a body (atrium), a temporal (inferior) horn occipital (posterior) horn. Interventricular foramen (of Monro) at the junction of the anterior horn and the body connects each lateral ventricle with the third ventricle Frontal: Its roof and anterior extremity are formed by the corpus callosum, The head of the caudate nucleus makes a prominent impression There is no choroid plexus in the anterior horn into the frontal lobe. SEPTUM PELLUCIDUM 57 Body This is within the parietal lobe. Thalamus lies in the floor medially, with the body of the caudate nucleus laterally and the thalamostriate groove and vein between Temporal (inferior) horn Caudate nucleus tail lies in the roof of the inferior horn. Hippocampus forms the floor of the inferior horn. are small or not visible unless they are dilated Occipital horn arises from the posterior convexity of the body which is called the trigone. The occipital horn may be absent or poorly developed, or may extend the full depth of the lobe. Often asymmetrical . If the posterior horn is present on one side only it is usually the left. There is no choroid plexus in the occipital horn Third ventricle slit-like space between the thalami. Its width is between 2 and 10 mm and increases with age. lateral walls the thalami. floor structures of hypothalamus. The thalami are connected across the ventricle in 60% of subjects by a non-neural connection, the massa intermedia or interthalamic adhesion. Cerebral aqueduct Narrow channel connecting the posterior end of the 3rd vent. with the superior end of the 4th vent.. Measures1. 5 cm in length and 1-2 mm in diameter, Passes through the brainstem with the tectum (the quadrigeminal plate) posterior to it and the tegmentum and cerebral peduncles anteriorly Fourth ventricle floor is diamond-shaped (the rhomboid fossa) and is formed by the posterior surface of the pons and of the upper part of the medulla. roof is formed: superiorly by the superior cerebellar peduncles, with the superior medullary velum between, and inferiorly by the inferior cerebellar peduncles and the inferior medullary velum. Over these lies the cerebellum . Fourth ventricle Three openings are present in the lower part of the roof : Single Median aperture (of Magendie) which communicates with the cisterna magna. Two Lateral apertures (of Luschka) at the apex of lateral recesses (lateral prolongation of cavity of the 4th vent. on each side ) and open anteriorly into the pontine cistern NOTE: 4th & 3rd ventricles and the aqueduct tend to be symmetrical in its anatomy and minor asymmetry may be a sign of pathology Interesting!! The Rt. and Lt. sided dominance is anatomically expressed by a mild hemispheric hypertrophy that is at its most in the occipital region: In such cases, the left occipital lobe, extends slightly farther back than the right one, sometimes scalloping the occipital bone, sometimes bulging on the midline. The left occipital horn is usually longer than the contralateral, and the left transverse venous sinus is lower and smaller than the right one in about 50% of individuals The coronal T2WI and FLAIR images show right-sided mesial temporal sclerosis. Notice the volume loss, which indicates atrophy and causes secondary enlargement of the temporal horn of the lateral ventricle. The high signal in the hippocamous reflects gliosis. vertebral artery and its PI cerebellar branch. 2-Pontine (pre-pontine 4-Quadrigeminal (cistern of the great vein) Ambient cisterns (yellow arrow) 1-suprasellar cisterns confluence of the internal cerebral veins and the basal veins to form the vein of Galen Posterior cerebral artery and the basal vein optic nerves, anterior part of the circle of Willis Major venous sinuses
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