ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: MSK Tribology and Biomechanics (Session 1A) MONDAY, 7TH SEPTEMBER 2015 (DAY ONE) Artificial joints biomechanics and biotribology Mazen Al-Hajjar: Variations in rotational and translational surgical position can lead to increased frictional torque in total hip replacements Ziyun Ding: An improvement of knee load predictions using a morphologically-similar lower limb anatomy model Abdellatif Abdelgaied: Influence of Simulation Input Conditions on the Wear of Total Knee Replacement John O'Connor: Biomechanical consequences of medialising joint centre of rotation following Total Hip Replacement (THR): A computational study Mazen Al-Hajjar Dr Mazen Al-Hajjar is currently a senior research fellow at the University of Leeds who leads part of the hip replacement tribology research. He was awarded a prestigious BORS international fellowship in 2014. He has received his Doctorate degree from the University of Leeds in 2013 in the field of Joint replacement technology. Thesis title: "Wear of Hard-on-Hard Hip Prostheses: Influence of Head Size, Surgical Position, Material and Function". He has published articles in peer reviewed scientific journals and presented his research findings in over thirty national and international meetings. Ziyun Ding Ziyun Ding is a research associate in the Department of Bioengineering, Imperial College London. She received her PhD degree in Mechanical Engineering in the University of Liverpool, Liverpool, UK; MEng in Mechanical and Electrical Engineering and BEng in Mechanical Engineering and Automation in the Nanjing University of Aeronautics and Astronautics, Nanjing, China. Her research interests include lower limb musculoskeletal modelling, ergonomics analysis, computer programming using C++ and MATLAB. Abdellatif Abdelgaied Abdellatif Abdelgaied is a Mechanical Engineer working in the biomedical engineering sector as a Post-doctoral Research Fellow at the University of Leeds. He holds a PhD in Biomedical Engineering (University of Leeds, 2012), MEng (2006) and BEng (1999) in Mechanical Engineering (Helwan University, Cairo). Design, tribology, experimental and computational simulations of medical implants, and biomechanical evaluation of scaffolds are his areas of interest. Abdellatif works in collaboration with DePuy Synthes UK, Invibio Ltd UK, and Tissue Regenix plc UK. John O'Connor Currently in the first year of a PhD (Mechanical Engineering) at Queen’s University Belfast, my project is focused on modelling component placement in total hip replacement surgery. Initial work has been on multibody dynamics and finite element analysis modelling. I graduated with a first class honours B.E. in Biomedical Engineering from National University of Ireland Galway (2014) and have previously worked as a manufacturing engineer and a project engineer. My interests are in computational modelling, particularly musculoskeletal and cardiovascular applications. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: MSK Tribology and Biomechanics (Session 1B) MONDAY, 7TH SEPTEMBER 2015 (DAY ONE) Natural joint biomechanics and biotribology Marlene Mengoni: Investigation of the effect of including fibre orientation in the intervertebral disc of a cervical ovine FSU in-silico model Iain Hannah: Modelling the distribution of vertical force in multi-segment foot models Darshan Shah: Control of a wrist joint motion simulator: a phantom study Danielle Miles: Developing a standardized in-vitro methodology to examine the biomechanical performance of novel nucleus replacement procedures Marlene Mengoni Marlene Mengoni is a Research Fellow in spine biomechanics at the institute of Medical and Biological Engineering (University of Leeds). She is interested in microscale aspects of tissue biomechanics with a fundamental computational engineering approach. She holds a PhD in Computational Biomechanics from the University of Liège (Belgium) and an MSc in Physical Engineering. Her current work examines the micromechanical aspects of the intervertebral disc and was selected as finalist of the ESB Clinical Biomechanics award in 2014. Iain Hannah Iain Hannah is a Postdoctoral Research Associate working in the modelling of musculoskeletal biomechanics at the University of Sheffield’s INSIGNEO Institute for in silico Medicine. In 2014 he graduated from Loughborough University's Sports Technology Institute with a PhD in Mechanical Engineering. His thesis was on the finite element modelling of the shod human footstrike and was completed in collaboration with the adidas Innovation Team. Darshan Shah Darshan Shah is currently working towards his PhD in Musculoskeletal Biomechanics at Imperial College London. Having witnessed a surgery on his grandfather’s fractured femur during his undergraduate degree, he decided to pursue orthopaedic biomechanics and completed his Master’s in Mechanical Engineering from the Indian Institute of Technology Bombay, where he worked on Total Knee Arthroplasty implants. He then moved to London and gained an MSc in Bioengineering at Imperial College, where he worked on developing a lower limb amputation implant at the Centre for Blast Injury Studies. Danielle Miles Danielle graduated with a 1st class MChem with industrial experience in 2008. She stayed at Leeds for her PhD working on self-assembling de novo peptides in physiological conditions, under the supervision of Prof Ruth Wilcox. During her PhD Danielle won numerous prizes including the University postgraduate researcher of the year 2010. She is now a research fellow based within the School of Chemistry and a member of the Institute of Medical and Biological Engineering at the University of Leeds. Her current work concerns the development of peptide hydrogels for intervertebral disc therapies. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Digital Health II Marzieh Tehrani: An Agent-Based Model of Interacting Stem Cells and Cancer Cells Digital Health (Session 1B) MONDAY, 7TH SEPTEMBER 2015 (DAY ONE) Marzieh Tehrani I am a second year postgraduate student working on a multidisciplinary PhD at the University of Sheffield's Insigeno institute. My undergraduate degree is in biomedical engineering and was obtained from the University of Sheffield, June 2013. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Regenerative Devices (Session 1A) MONDAY, 7TH SEPTEMBER 2015 (DAY ONE) Regenerative Devices; Orthopaedic applications Andrew Pattinson: Developments in processing functionally graded osteochondral cellconducting materials' Jennifer Edwards: Effects of chemical and irradiation sterilisation plus long term storage on the biological properties of an acellular xenogenic tendon Anthony Herbert: An Investigation into the Biomechanical Effects of Decellularisation on Human Bone-Patellar Tendon-Bone Grafts for Use in Anterior Cruciate Ligament Replacement Alam Khalil-Khan: Uses of joint resident Mesenchymal Stromal Cells for articular cartilage repair Andrew Pattinson Dr. Andrew Pattinson is a Postdoctoral Research Assistant at the University of Bradford. He received both his BEng (Hons) and his PhD from Bradford. Currently his research involves developing processing routes for functionally gradient osteochondral cell-conducting materials. Dr Pattinson has also received a PGCE at the University of Leeds and presently works part time with special educational needs students, specialising in secondary science and mathematics. Jennifer Edwards I am a postdoctoral research fellow working on acellular grafts for the repair and regeneration of ligamentous tissues, using tendons to produce and characterise acellular scaffolds, develop decellularisation methods and investigate terminal sterilisation. I have produced grafts for proof of concept studies, requiring aseptic dissection and processing of tissue. Characterisation includes biochemical assays, histology and biocompatibility testing. I am keen to increase my interaction with clinicians and clinical need, as well as engaging with the public about biomedical research. Anthony Herbert I have been performing research into soft tissue mechanics for approximately 8 years, primarily with the goal of developing products for interventional regenerative medicine. I completed my doctorate of engineering in medical devices in 2011, following which I began my current postdoctoral position in experimental biomechanics of acellular biological scaffolds for anterior cruciate ligament replacement. To date, this has involved conducting mechanical testing of the products and liaising with clinicians and external test centres to develop surgical procedures for proof of concept studies. Alam Khalil-Khan Dr Alam Khalil-Khan is an Orthopaedic surgical trainee/Clinical Research Fellow at NIHR/University of Leeds/Leeds Teaching Hospitals. Currently undertaking his M.D in "Uses of joint resident Mesenchymal Stromal Cells for articular cartilage repair." Qualification: MBBS Medicine, University Of Newcastle Upon Tyne, Medical School 2004-2009. MSc Medical Engineering & Biomechanics, University Of Leeds, Woodhouse Lane, Leeds. 2001-2002 / BSc Medical Sciences. ,University Of Leeds, Woodhouse Lane, Leeds. 1998-2001 ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Regenerative Devices (Session 1B) MONDAY, 7TH SEPTEMBER 2015 (DAY ONE) Regenerative Devices; Non-Orthopaedic applications Samantha Wilson: Investigating the use of dextran in corneal decellularisation: how, where, and if? M Tarik Arafat: Wet-spun collagen triple helices as an implantable matrix for the controlled release of antibacterial drugs Tayyebeh Vafaee: Decellularisation of allogeneic aortic and pulmonary valves using low concentration SDS Andrew Aldridge: Development and characterisation of a large diameter acellular vascular bypass graft Samantha Wilson Dr Samantha Wilson (Sammy) is an EPSRC E-TERM research fellow, currently based at Academic Ophthalmology, University of Nottingham. Sammy has a PhD from Keele University in Biomedical Engineering, specifically looking at the development & characterisation of corneal biomimetic tissues. Her current research focuses on developing corneal decellularisation procedures to produce matrices which may be utilised in two key areas: i) as an effective engineered construct for corneal transplantation; ii) a more relevant model for drug & irritant testing in order to reduce / refine / replace animal models. M Tarik Arafat Dr Arafat is working as a Research Fellow in Clothworkers’ Centre for Textile Materials Innovation for Healthcare & Biomaterials and Tissue Engineering Group, School of Dentistry, University of Leeds. He is working on the stratified design and manufacture of nonwoven collagen scaffolds, and the project is funded by MeDe Innovation of EPSRC centre for innovative manufacturing in medical devices. In this project he is responsible to establish a working manufacturing process to fabricate collagen and functionalized collagen filaments and design filament for medical device assembly. Tayyebeh Vafaee Dr.T.Vafaee, MD, PhD Research Fellow, Institute of Medical and Biological Engineering, University of Leeds, UK. Research activities: Cardiac valve tissue engineering,Translational research of Acellular Allogeneic & Xenogeneic Cardiac Valves(University of Leeds, UK); Investigation of epidermal H2O2mediated oxidative stress in human pigmentary disorders (University of Bradford, UK ); Investigation of molecular and cellular biology of human hair pigmentation in health and disease (University of Bradford, UK ). Worked as GP & Obstetrician / Gynecologist (internationally). Andrew Aldridge After finishing my undergraduate in Biochemistry and Medical Biochemistry at Leeds University I went onto complete a Masters in Infection and Immunity. This led onto my PhD on the immunogenicity of adult human multipotent mesenchymal stromal cells (MSCs). Since the completion of this I started my first post-doctoral research position working on the development of a large diameter vascular graft for the NHS Blood and Tissue Transplant Service. Currently I am looking at the assessment of the recellularisation of decellularised human tissue (amnion, tendon & bone) with adult stem/precursor cells. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Osteoarthritis – novel treatments Ruth Craven: Interactions of cobalt chromium and ceramic wear particles from total hip replacements with the cell plasma membrane Mansour Youseffi: Development of Novel Hydrogels Based on Chitosan/Gelatin/BGlycerophosphate for Replacement and Repair of Diseased Articular Cartilage: A Dynamic Characterization Hazel Fermor: Development of an acellular xenogeneic osteochondral biomaterial for cartilage repair Osteoarthritis (Session 2A) TUESDAY, 8TH SEPTEMBER 2015 (DAY TWO) Ruth Craven A final year PhD student studying the biological responses to metal and ceramic wear particles from total hip replacements. In particular the effect of these wear particles on the cell plasma membrane. Mansour Youseffi Senior lecturer in engineering materials and head of medical and healthcare technology department at the University of Bradford. Hazel Fermor Dr Fermor has a BSc in biology from the University of York and a PhD from the University of Leeds. Research for her thesis 'Engineering of natural cartilage substitution biomaterials'• has contributed toward a patent and a number of peer reviewed publications. Dr Fermor continues to research acellular composite biological scaffolds for musculoskeletal regenerative medicine at Leeds. Concomitantly, she has continued to develop skills for the commercialisation of translational research, winning Chemistry YES in 2014 and completing a PG Cert in Professional Innovation Management. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Osteoarthritis – Tissue Characterisation and Tissue Repair Rachel Pallan: Comparison of porcine acetabulum labrum and cartilage in terms of biological characterisation and structure Qingen Meng: The effect of collagen fibril orientation on articular cartilage biomechanics Alexander Bates: Reliability of lower limb three-dimensional kinematics in people with generalised joint hypermobility Joshua W Giles: A Novel Patient Specific Guide For Minimally Invasive Total Shoulder Arthroplasty Rachel Pallan Osteoarthritis (Session 2B) I am in my final year of my PhD on the DTC Tissue Engineering and Regenerative Medicine at the University of Leeds. I also completed a masters in Mechanical Engineering the University of Leeds. My work focuses on abnormal morphologies of the hip, in diseases such as femoroacetabular impingement. I also look at the characterisation of the acetabular labrum in both porcine and human tissue. Qingen Meng Dr Qingen Meng is a postdoctoral research fellow at the iMBE of the University of Leeds, working on biomechanics and biotribology of soft tissues (cartilage and meniscus) and natural joints (the knee). Before he started his postdoc job, he finished his PhD, which focused on biomechanics and biotribology of artificial hip joints, at the same institute. He has published 2 book chapters, 12 journal papers and 11 conference papers in biomedical engineering. He is an active member of two biomedical research societies: Orthopaedic Research Society and European Society of Biomechanics. Alexander Bates Alex Bates is a PhD student within the department of Surgery and Cancer at Imperial College London. After graduating with a Biology BSc from the University of Sheffield in 2005, Alex consolidated his knowledge of biomechanics with a Masters degree in Biomedical Engineering from the University of Surrey in 2012. His PhD under the supervision of Dr. Caroline Alexander and Professor Alison McGregor is associated with investigating the kinematics and kinetics of people with Joint Hypermobility Syndrome. Joshua W Giles Dr. Giles is a Research Associate in the Mechatronics in Medicine and Biomechanics labs at Imperial College. His research, as part of a Wellcome Trust project, focuses on the design of novel surgical techniques and instrumentation for shoulder arthroplasty. Joshua completed his Doctorate in Biomedical Engineering (Orthopaedic Biomechanics) at the Hand & Upper Limb Centre, Western University, London, Canada. He focused on developing in-vitro testing systems that replicated the joint’s in-vivo environment to allow the investigation of questions relating to orthopaedic injuries and interventions. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Imaging, Modelling and Devices (Session 2A) TUESDAY, 8TH SEPTEMBER 2015 (DAY TWO) Modelling and Devices Session Daniel Nolte: Statistical shape modelling research toolbox (SSMRT) – simplifying the creation of subject-specific geometries for musculoskeletal analysis Desmond Dillon-Murphy: A Systematic Study of the Determinants of False Lumen Pressure in Type B Aortic Dissection Eleni Bazigou: Effect of altered blood flow on arterial permeability in immature and mature rabbits Lei Zheng: A sensitive biosensor for electrochemical detection of microRNA based on isothermal strand displacement polymerase reaction and electrochemical sensing technology Sebastien Sikora: Modelling patient variation for implant design using a principal component analysis based approach Daniel Nolte Daniel Nolte is currently working as researcher in the Department of Bioengineering at Imperial College London, focusing on statistical shape modelling and musculoskeletal simulation. He gained experiences with musculoskeletal simulation at his previous post as software developer with AnyBody Technology, Denmark. Prior to this, he worked at the Scientific Computing Centre Ulm (UZWR) in Ulm University, Germany, on interdisciplinary projects of the Institute of Numerical Mathematics and the Institute of Orthopaedic Research and Biomechanics, Ulm. Desmond Dillon-Murphy Desmond Dillon-Murphy has a BEng in Mechanical Engineering from Dublin Institute of Technology, 2004, a First place MSc in Bioengineering from Trinity College Dublin, 2007 and began his PhD in Blood Flow Modelling with a focus on aortic dissection, Kings College London in 2012 with previous experience in software, design and construction, and the health care industry. Eleni Bazigou My research interests lie in the field of mechanobiology and network remodelling. I obtained my BSc in molecular neurobiology from King's College London and my PhD in developmental genetics from the National Institute for Medical Research. I have worked on both neuronal and vascular remodelling (Cancer Research UK) and I am currently (Bioengineering, Imperial College London) developing skills to further examine these processes in the arterial system by being a part of a multidisciplinary team and using different qualitative and quantitative methods. Lei Zheng Professor Zheng, a doctor of medicine(M.D.) ,doctoral supervisor,who is the deputy director of the clinical laboratory and the director of circulating biomarker test lab in Nanfang hospital. He is currently the chairman of Guangdong Society of Laboratory Medicine (belonging to Guangdong Province Medical Association) from 2014 to 2018 ,the academic member of Chinese Society of Laboratory Medicine, the expert group members of clinical blood and body fluids of Chinese Society of Laboratory Medicine and member of the standing committee in GuangDong Medical Doctor Association of Lab Medicine. Sebastien Sikora After studying mechanical engineering at the University of Hull and completing an MEng with distinction at the University of Leeds, Seb returned to Leeds to complete a PhD on the computational and experimental study of trabecular bone-cement interfaces. He remains within the iMBE, turning his passion for problem solving to the use of principle component analysis based techniques to aid in the modelling of patient variation for implant design and more recently the development of experimental testing methodologies for the evaluation of peptide hybrid hydrogels for intervertebral disc therapies. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Imaging, Modelling and Devices (Session 2B) TUESDAY, 8TH SEPTEMBER 2015 (DAY TWO) Imaging Session Junaid Muhammad: Compressed Sensing (CS) Image Reconstruction using TV and Wavelet Constraints Megan Rutherford: Impact of pelvic position on acetabular orientation Rashed Karim: An MR compatible robot-assisted ablation catheter with steering based on imaging, tension and contact-force Samuel Vennin: From aortic flow velocity to central pressure: a non-invasive proof of concept Ana Mercedes Campos Marin: u-Particle image velocimetry and computational fluid dynamics study of cell seeding within a 3D porous scaffold Junaid Muhammad I am interested in Medical Imaging, MRI, Compressed Sensing, Mathematics, physics and NonCartesian Imaging etc. I enjoy the challenge of using scientific and mathematical (inverse problem) ideas when solving everyday problems. While attending the University, I have enjoyed many opportunities to learn about the computers and programming. Hands-on experiences in the lab, and lectures from leading researchers engaged my mind and captured my interest. I'm now working as a C++ Developer in Concurrent Systems, Pakistan. I'm formal student of COMSATS Institute of IT, Pakistan. Megan Rutherford I am a second year PhD student at Queens University Belfast within the school of Mechanical and Aerospace Engineering. Rashed Karim Rashed Karim completed a PhD in image processing algorithms from Imperial College London. He currently develops image processing algorithms with applications ranging from tissue detection to computer-assisted surgery. He is a research fellow at King's College London and an honorary lecturer at Imperial College London. Samuel Vennin After electrical engineering studies in France, I obtained a MSc degree in Bioengineering at Imperial College London. My master thesis was investigating a new technique to palpate tissues using microbubbles and ultrasound. Now at King's College London British Heart Foundation Centre, I am pursuing a PhD in cardiovascular medicine. My aim is to develop a non-invasive method to obtain the left ventricular pressure. Ana Mercedes Campos Marin I hold a Mechanical Engineering degree (5 years degree) and currently I am a third year PhD student in INSIGNEO in the Mechanical Engineering Department under the supervision of Prof. Damien Lacroix. My work focuses on the development of a computational model able to predict cell seeding efficiency in 3D scaffolds during in vitro experiments. For this model, well characterized data was required and for that I spent 5 months in Politecnico di Milano (Italy) under the supervision of Prof.Gabriele Dubini funded by Mobility Award for Young researchers (European Society of Biomechanics). ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Medical and Bioengineering (Session 2A) TUESDAY, 8TH SEPTEMBER 2015 (DAY TWO) Medical and Bioengineering 1 Eirini Velliou: On the quantification of the role of environmental stress on the response of leukaemic cells to chemotherapy in a 3D ex vivo bone marrow mimicry Ayesha Bint-E-Siddiq: Mechanical Characterisation and Computational Modelling of Spinal Ligaments Yiorgos Kanellos: Design of medical device technology for the production and evaluation of patient specific materials for use in orthoplastic surgery Oscar O'Dwyer Lancaster-Jones: Variations in hip implant surgical positioning can affect the level of dynamic microseparation, edge-loading occurrence and severity of wear Eirini Velliou Dr. Eirini Velliou is a Lecturer at the Department of Chemical and Process Engineering of the University of Surrey, UK. Her research interests fall within understanding the impact of environmental stress on the response, resistance and metabolic activity of biological systems, i.e., human cancerous, microbial and micro-algae cells. The last years she has been studying the impact of oxidative and nutrient stress on the resistance of cancerous (leukaemic and more recently pancreatic) cells to treatment (chemotherapy, radiotherapy) in 3D systems that mimic in vitro the in vivo microenvironment. Ayesha Bint-E-Siddiq I am a PhD researcher at the Institute of Medical and Biological Engineering (IMBE), University of Leeds. My research involves characterizing the mechanical properties of spinal ligaments and establishing a methodology for specimen specific modelling of ligaments. I hold a MEng in Medical Engineering from Queen Mary, University of London. Outside of work, I actively engage in outreach activities; and as an associate member of the IMechE, I am the Honorary secretary for North Yorkshire young members committee, working towards getting chartered. Yiorgos Kanellos Yiorgos Kanellos is a final year EngD student at the University of Strathclyde. Oscar O'Dwyer Lancaster-Jones Oscar O’Dwyer Lancaster-Jones is currently a PhD student at the University of Leeds. His research activity involve understanding the effect of variations in surgical positioning of total hip joint replacements on their functional performance and their effect on the wear. Oscar’s current research is contributing to the stratified approach for enhanced reliability (SAFER) for preclinical testing of joint replacement. His background is in Mechanical Engineering and has completed a Masters in Medical Engineering at Queen Mary University of London. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: Medical and Bioengineering (Session 2B) TUESDAY, 8TH SEPTEMBER 2015 (DAY TWO) Medical and Bioengineering 2 Eric Kerfoot: Software framework for cardiac motion tracking using tagged MRI Ye Li: Do backward pressure waves arise from reflections or from a reservoir? Kok Yean Chooi: Smooth muscle tone-dependent hydraulic conductance of aortic media Zahra Mohri: Haemodynamic wall shear stress, wall permeability and lesion frequency in the mouse aortic arch-role of PECAM-1 Eric Kerfoot Eric Kerfoot graduated from the University of Western Ontario in 2005 with a HBSc in Computer Science and received his DPhil in computing from the University of Oxford in 2010. His current research includes biomedical data visualization, image processing and analysis. Lauren Fovargue received her BSc in Mathematics from the University of Central Florida in 2007 and in 2012 completed her PhD at the University of North Carolina in Applied Mathematics. Currently her research is on patient-specific electro-mechanical modelling and simulation for clinically focused workflows. Ye Li I am a postdoctoral research associate working in Clinical Pharmacology, King's College London. My research interests are mainly focused on using numerical modelling and physiological measurements to characterise the cardiovascular haemodynamics, e.g. pulse wave velocity, central blood pressure, ventricular-arterial coupling, which might give useful explanation and prediction of cardiovascular diseases. Kok Yean Chooi Yean Chooi gained his degree in Biomedical Engineering (MEng, 1st class) in 2011 from Imperial College London. In 2011, he was awarded a studentship on the MRes/PhD program in the BHF Centre of Research Excellence at Imperial College, conducting his MRes research in the laboratories of Profs Peter Weinberg, Molly Stevens and Michael Schneider. His current research, as a PhD student in the groups of Profs Peter Weinberg and Spencer Sherwin, investigates the roles of mass transport mechanisms in the arterial wall using a combination of experimental techniques and numerical simulations. Zahra Mohri Zahra obtained her PhD in Biochemistry from Royal Free Hospital before joining the institute of Cancer Research as a Postdoctoral Fellow in 2005 working on glioblastoma therapy with Paul Workman. In 2008, Zahra joined Peter Weinberg’s team in Imperial College London as a Research Associate, studying the effect of permeability and flow in the development of vulnerable plaques. She is currently investigating the proposal that endothelial cells have a “comfort zone” for mechanical stresses and that they express a pro-atherogenic phenotype when exposed to stresses outside this zone. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: The Delivery of Regenerative Medicine (Session 2A) TUESDAY, 8TH SEPTEMBER 2015 (DAY TWO) Cells and Scaffolds Maryam Shariatzadeh: Effect of Mechanical Stimulation on Osteogenic differentiation of SelfAssembled Collagen-Cell Seeded scaffolds Robert Owen: PolyHIPE Scaffolds with Tunable Mechanical Properties Peter Iddon: Translation of EktoTherix™, a synthetic acellular scaffold for wound regeneration: learning by doing Maryam Shariatzadeh Maryam Shariatzadeh is a final year PhD student in department of Mechanical Engineering at University of Sheffield. Maryam completed her Master of Science in Biotechnology in chemical and analytical sciences department at University of Manchester and her PharmD doctorate degree at Tehran medical sciences university. Maryam research interests lies in the area of molecular /cellular biology and bio engineering with the main focus on designing natural based Biomaterial employed in tissue engineering and regenerative medicine. Robert Owen Robert Owen is a PhD student within the INSIGNEO Institute for in silico Medicine at the University of Sheffield. Having received a Master's degree in Biomaterial Science and Tissue Engineering in 2014, Robert continued his research under the supervision of Dr. Gwendolen C Reilly, Prof. Damien Lacroix, and Prof. Ilaria Bellantuono. His focus is on applying the principles of bone tissue engineering to developing an in vitro model of osteoporosis. Peter Iddon Dr Peter Iddon's expertise is in the area of polymer chemistry. Prior to joining Neotherix, Peter worked as a Biomaterials Specialist for Smith & Nephew where he was involved in the development of the electrospinning process used for Neotherix scaffolds. He has held positions with ICI and P&G and is an inventor on 4 patent applications. ORAL PRESENTER BIOGRAPHIES Biographies are listed in order of the Programme Session Title: The Delivery of Regenerative Medicine (Session 2B) TUESDAY, 8TH SEPTEMBER 2015 (DAY TWO) Processing and Delivery of Cell-based Therapies Shiraz Ziya: Using process engineering maps in the clinic to better understand an autologous cell-based therapy Elizabeth Stoll: Advances toward regenerative medicine in the central nervous system: challenges in making stem cell therapy a viable clinical strategy Alex Lyness: Overcoming the translational challenges of the effective administration and delivery of cell-based therapies Shiraz Ziya Shiraz is a PhD student at RJAH Orthopaedic Hospital NHS Foundation Trust (Keele University), part of the EPSRC Doctoral Training Centre in Regenerative Medicine. He has a degree in Biochemistry from University of York and a Master's in Translational Medicine from University of Manchester. He has industrial experience, including a placement year with GlaxoSmithKline, as well as a technical support role at UK Biobank. These have developed his interest in the manufacturing, commercialisation and delivery of cell-based therapies, with a focus on improving the clinical pathway. Elizabeth Stoll Elizabeth Stoll was born in Chicago, USA. She completed her doctoral studies in Neurobiology & Behaviour at the University of Washington in Seattle, USA, under the supervision of Dr Philip Horner and Dr Robert Rostomily. She moved to the U.K. to undertake post-doctoral research in the laboratory of Professor Doug Turnbull at Newcastle University. She currently studies the regulation of neural stem cell activity, particularly during ageing and oncogenic transformation. Alex Lyness Dr Alex Lyness BEng MSc PhD has been working at the academic-industry interface for 7 years; since graduating his research has been sponsored by big and small pharma, and start-ups. His PhD was in needle-free drug delivery and gained whilst working for Glide Pharma, Oxford. Alex now holds an Enterprise Fellowship at Loughborough University; his work is focused on developing and commercialising novel delivery devices for cellular therapies.
© Copyright 2024