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Research
Knowledge Forum SCI & Trauma
2015-Q1 Report
Steering committee
Alex Vaccaro (Chairperson Trauma)
Thomas Jefferson University
Philadelphia, USA
Start of Term: 01 Apr 2013
End of Term: 30 Jun 2016
Michael Fehlings (Chairperson SCI)
University of Toronto
Toronto, Canada
Start of Term: 01 Apr 2013
End of Term: 30 Jun 2016
Jens Chapman (Trauma)
Swedish Neurosciene Institute
Seattle, USA
Start of Term: 01 Jan 2012
End of Term: 31 Dec 2016
Bizhan Aarabi (SCI)
University of Maryland
Baltimore, USA
Start of Term: 01 Jan 2012
End of Term: 31 Dec 2016
Cumhur Oner (Trauma)
University Medical Center
Utrecht, Netherlands
Start of Term: 01 Jan 2012
End of Term: 31 Dec 2016
Marcel Dvorak (SCI)
Vancouver General Hospital
Vancouver, Canada
Start of Term: 01 Jan 2012
End of Term: 31 Dec 2016
Frank Kandziora (Trauma)
Unfallklinik Frankfurt
Frankfurt, Germany
Start of Term: 01 Jan 2012
End of Term: 31 Dec 2016
Robert Grossman (SCI)
The Methodist Hospital
Houston, USA
Start of Term: 01 Jan 2012
End of Term: 31 Dec 2016
S. Rajasekaran (Trauma)
Ganga Hospital
Coimbatore, India
Start of Term: 01 Mar 2012
End of Term: 28 Feb 2015
New Knowledge Forum Manager
María Alvarez Sánchez
AOSpine International
Clavadelerstrasse 8
7270 Davos
Switzerland
T +41 81 414 27 36
[email protected]
Projects
Spine Trauma Classification
Title: Development of an AOSpine trauma injury classification
system.
Aim: To develop and validate a comprehensive classification system
of traumatic spine injuries: phase 1: TL system, phase 2: cervical
system and phase 3: pelvic system
Principal Investigator: Alex Vaccaro
Co-Principal Investigator: Cumhur Oner
Co-investigators TL system:
Name
Institute
City
Country
Region
Chris
Thomas Jefferson University
Philadelphia
USA
NA
Schnake
Klaus
Schön Klinik Nürnberg Fürth
Fürth
Germany
EU
Bellabarba
Carlo
University of Washington
Seattle
USA
NA
Reinhold
Max
Klinikum Südstadt
Rostock
Germany
EU
Vialle
Luiz
Catholic University
Curitiba
Brazil
LA
Last
First
Kepler
Collaborating Surgeons TL system validation:
Region
Number
Asia Pacific
35
Europe
17
North America
18
Latin America
20
Middle East
18
Africa
1
Publications:
•
Abstract submitted: 0
•
Podium presentation: 9
•
Manuscripts submitted: 6
•
Manuscripts published: 7
Awards & Nominations: None
Status:
•
•
•
TL system: Data analysis and reporting
Cervical system: Planning
Pelvic system: Planning
Link: Surgery Reference
https://www2.aofoundation.org/wps/portal/surgery?showPage=di
agnosis&bone=Spine&segment=TraumaThoracolumbar
Outcome measurement
Title: Development of an AOSpine trauma outcome instrument
Principal Investigator: Cumhur Oner
Aim: To develop and validate a multidisciplinary and universal
outcome instrument for spinal trauma patients, which includes
both the patients’ and health professionals’ perspective on health
and functioning.
•
Phase 1: define core set
•
Phase 2: international consensus conference
•
Phase 3: validation
Participating sites (empirical study):
Local PI
Institute
City
Country
Region
Alex
Thomas Jefferson University
Philadelphia
USA
NA
Oner
Cumhur
University Medical Center
Utrecht
Netherlands
EU
Fehlings
Michael
University of Toronto
Toronto
Canada
NA
Dvorak
Marcel
Vancouver General Hospital
Vancouver
Canada
NA
Vialle
Luiz
Catholic University
Curitiba
Brazil
LA
Aarabi
Bizhan
University of Maryland
Baltimore
USA
NA
Kandziora
Frank
Unfallklinik Frankfurt
Frankfurt
Germany
EU
Rajasekaran
Shanmuganathan
Ganga Hospital
Coimbatore
India
AP
Dunn
Robert
Groote Schuur Hospital
Cape Town
South Africa
EU
Last
First
Vaccaro
Publications:
•
Abstracts presented: 2
•
Podium presentation: 5
•
Manuscripts submitted: 2
•
Manuscripts published: 2
Awards & Nominations: None
Status: Executing - data analysis
Value of CT and MRI
Title: The additional value of CT and MRI in determining the
fracture severity and management in spinal column injuries
Aim: To define and determine the value of a CT scan and an
MRI in addition to plain radiographs in a cohort of spinal
fractures of various severities
Principal Investigator: Shanmuganathan Rajasekaran
Co-Investigators: n/a
Collaborating Surgeons CT/MRI study:
Region
Number
Asia Pacific
14
Europe
5
Latin America
12
Middle East
7
North America
2
Africa
1
Publications:
•
Abstracts presented: 0
•
Manuscripts: 0
Awards & Nominations: None
Status: Disseminating
Thoracolumbar Burst Fractures
Title: Thoracolumbar Burst Fractures (AOSpine A3, A4) in
neurologically intact patients: An observational, multicenter
cohort study comparing surgical versus non-surgical treatment
Principal Investigator: Marcel Dvorak
Co-Investigators: Cumhur Oner
Publications:
•
Abstracts presented: 0
•
Manuscripts: 0
Awards & Nominations: None
Status: Planning
Aim: To establish and quantify the difference in the patients’
clinical outcome after surgical treatment as compared to nonsurgical treatment of thoracolumbar burst fractures at 1 year after
treatment with the Oswestry Disability Index (ODI).
SCI Database Merge
Title: Spinal Cord Injury (SCI) Database Merge: Combining data
of two existing registries (NACTN and STASCIS)
Principal Investigator: Michael Fehlings
Aim: To combine two existing databases on patients with spinal
cord injuries treated surgically (NACTN and STASCIS) and to
assess descriptive data on injury/surgery details, as well as ASIA
score and reported complications.
Publications:
•
Abstracts presented: 0
•
Manuscripts: 0
Awards & Nominations: None
Status: Executing – data analysis
RISCIS
Title: A Multi-Center, Randomized, Placebo-Controlled, DoubleBlinded, Trial of Efficacy and Safety of Riluzole in Acute Spinal
Cord Injury
Principal Investigator: Michael Fehlings
Co-Investigators: Open call for applications completed; eight sites
enrolled.
Aim: The aim of this study is to evaluate efficacy and safety of
Riluzole in the treatment of patients with acute spinal cord injury.
The primary objective is to evaluate the superiority of Riluzole as
compared to placebo, in improving motor outcomes as measured
by ASIA Motor Score at 6 months follow-up, in patients with
acute traumatic spinal cord injury, presenting to hospital less than
12 hours after injury.
Co-sponsoring: AOSpine North America, U.S. Department of
Defense, Christopher and Dana Reeve Foundation, Ontario
Neurotrauma Foundation, Rick Hansen Institute.
Participating sites:
Local PI
Recruited
patients
Institute
City
Country
Region
Michael
Toronto Western Hospital
Toronto
Canada
NA
Ball
Jonathon
Royal North Shore Hospital
Sydney
Australia
AP
Aarabi
Bizhan
University of Maryland
Baltimore
USA
NA
5
Shaffrey
Christopher
University of Virginia
Charlottesville
USA
NA
2
Harrop
James
Jefferson University
Philadelphia
USA
NA
2
Nassr
Ahmad
The Mayo Clinic
Rochester
USA
NA
3
Brodke
Darrel
University of Utah
Salt Lake City
USA
NA
Arnold
Paul
Kansas University Medical Center
Kansas City
USA
NA
Theodore
Nicholas
Barrow Neurological Institute at St. Joseph's
Hospital and Medical Center
Phoenix
USA
NA
Wilson
Ray
Washington University
St. Louis
USA
NA
Stanford
Ralph
Prince Wales Hospital
Sydney
Australia
AP
Schuster
James
University of Pennsylvania
Philadelphia
USA
NA
First
Last
Fehlings
1
3
Publications:
•
Abstract submitted: 3
•
Podium presentations: 6
•
Manuscripts submitted: 1
•
Manuscript published: 2
Awards & Nominations:
•
Nominated for the White Cloud Award at the 21st IMAST
International 2014
Status: Executing – data collection
SCI Guideline project (co-sponsoring AOSpine North America)
Title: Development of an Evidence-based Clinical Guideline for
the Treatment of Acute Spinal Cord Injury
Principal Investigator: Michael Fehlings
Co-Investigators: Open call for applications completed; eight sites
enrolled.
Co-sponsoring: AOSpine North America
Aim: A set of systematic reviews will serve as the basis of the
current state of the field. Based on this knowledge, a global
Publications:
•
Abstracts presented: 0
•
Manuscripts: 0
Awards & Nominations: None
Status: Executing – data collection
team of clinical experts in SCI will then go through the
rigorous process of developing evidence-based clinical
guidelines for the treatment of Acute Spinal Cord Injury
specific to the five selected topics:
•
•
•
•
•
Use of methylprednisolone
Timing of decompression
Role and timing of magnetic resonance imaging
Type and timing of anticoagulation
Type and timing of rehabilitation
Publication Summary
Abstracts
Submitted (under review)
1. Sadiqi S, Lehr AM, Oner FC. Towards the development of
an international disease specific outcome instrument for
spine trauma – surgeon reported outcome. Eurospine,
Compenhagen, Denmark, 2-4 September, 2015.
2. Sadiqi S, Lehr AM, Oner FC. Towards the development of
an international disease specific outcome instrument for
spine trauma – AO Patient Reported Outcome Spine
Trauma (AO PROST). Eurospine, Compenhagen,
Denmark, 2-4 September, 2015.
3. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 ASIA/ISCoS Joint Scientific Meeting
[American Spinal Injuria Association and International
Spinal Cord Society]. Montreal, Canada. May 14-16, 2015.
4. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 North American Spine Society Annual
Meeting. Chicago, IL. October 14-1, 2015.
5. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 Congress of Neurological Surgeons (CNS)
Annual Meeting. New Orleans, LA. September 27-30,
2015.
Accepted for Presentation
Podium Presentations:
1. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 International Meeting on Advance Spine
Techniques (IMAST). Kuala Lumpur, Malaysia. July 8-11,
2015.
2. Sadiqi S, Lehr AM, Oner FC. Towards the development of
an international disease specific outcome instrument for
spine trauma – results of an international consensus
meeting. 11th International Turkish Spine Congress. Izmir,
Turkey, 29April-3 May, 2015.
3. Sadiqi S, Lehr AM, Oner FC. Towards developing a
specific outcome instrument for spine trauma - An
empirical cross-sectional multicenter ICF-based study by
the AOSpine Knowledge Forum Trauma. 11th International
Turkish Spine Congress. Izmir, Turkey, 29April-3 May,
2015.
4. Sadiqi S, Lehr AM, Oner FC. Towards the development of
an outcome instrument for spine trauma – An international
survey of spinal surgeons. 11th International Turkish Spine
Congress. Izmir, Turkey, 29April-3 May, 2015.
5. Oner FC, Jacobs WC, Lehr AM, Sadiqi S. Towards the
development of a universal outcome instrument for spine
trauma – A systematic review and content comparison of
outcome measures used in spine trauma research. 11th
International Turkish Spine Congress. Izmir, Turkey,
29April-3 May, 2015.
6. Schroeder GD, Vaccaro AR, Kepler CK, Koerner JD,
Oner FC, Dvorak M, Vialle L, Aarabi B, Bellabarbra C,
Fehlings MG, Kandziora F. Establishing the Injury Severity
of Thoracolumbar Trauma: Confirmation of the
Hierarchical Structure of the AOSpine Thoracolumbar
Spine Injury Classification System. Global Spine Congress.
Buenos Aires, Argentina 2015.
7. Schroeder GD, Kepler CK, Chapman J, Oner FC, Dvorak
M, Vialle L, Aarabi B, Bellabarbra C, Fehlings MG,
Rajasekaran S, Schnake KJ, Reinhold M, Kandziora F,
Vaccaro AR. Is there a regional difference in morphology
interpretation of A3 / A4 fractures among different
cultures. Global Spine Congress. Buenos Aires, Argentina
2015.
8. Kepler CK, Vaccaro AR, Koerner JD, Chapman J, Dvorak
M, Kandziora F, Rajasekaran S, Aarabi B, Vialle L,
Fehlings MG, , Schroeder GD, Reinhold M, Audige L,
Schnake KJ, Bellabarbra C, Oner FC. Reliability Analysis
of the AOSpine thoracolumbar Spine Injury Classification
System by a Worldwide Group of Naïve Spinal Surgeons.
Global Spine Congress. Buenos Aires, Argentina 2015.
9. A Vaccaro AR, Kepler CK, Koerner JD, Chapman J,
Dvorak M, Vialle L, Aarabi B, Bellabarbra C, Fehlings
MG, Rajasekaran S, Schroeder GD, Schnake KJ, Reinhold
M, Kandziora F, Oner FC. AOSpine Subaxial Cervical
Spine Injury Classification System. Global Spine Congress.
Buenos Aires, Argentina 2015.
10. Sadiqi S, Lehr AM, Oner FC. Towards the development of
an international disease specific outcome instrument for
spine trauma. Global Spine Congress. Buenos Aires,
Argentina 2015.
11. CK, Koerner JD, Oner C, Fehlings MG, Aarabi B, Dvorak
M, Reinhold M, Kandziora F, Bellabarba C, Chapman J,
Vialle L, Vaccaro AR. “A Worldwide Analysis of the
Reliability and Perceived Importance of an Injury to the
Posterior Ligamentous Complex in AO Type A Fractures.”
The Lumbar Spine Research Society. Chicago, IL May
2015.
12. Vaccaro AR, Schroeder GD, Kepler CK, Oner F.C, Vialle
L, Kandziora F, Koerner JD, Kurd MF, Reinhold M,
Schnake KJ, Chapman J, Aarabi B, Fehling MG, Dvorak
M, “The Surgical Algorithm for the AOSpine
Thoracolumbar Spine Injury Classification System.” The
Lumbar Spine Research Society. Chicago, IL, May 2015.
13. Schroeder GD, Vaccaro AR, Kepler CK, Koerner JD,
Oner FC, Dvorak M, Vialle L, Aarabi B, Bellabarbra C,
Fehlings MG, Kandziora F. Establishing the Injury Severity
of Thoracolumbar Trauma: Confirmation of the
Hierarchical Structure of the AOSpine Thoracolumbar
Spine Injury Classification System. The International
Society for the Study of the Lumbar Spine. San Francisco,
June 2015.
14. Kepler CK, Vaccaro AR, Koerner JD, Chapman J, Dvorak
M, Kandziora F, Rajasekaran S, Aarabi B, Vialle L,
Fehlings MG, Schroeder GD, Reinhold M, Audige L,
Schnake KJ, Bellabarbra C, Oner FC. Reliability Analysis
of the AOSpine thoracolumbar Spine Injury Classification
System by a Worldwide Group of Naïve Spinal Surgeons.
The International Society for the Study of the Lumbar
Spine. San Francisco, June 2015.
15. Schroeder GD, Vaccaro AR, Kepler CK, Koerner JD,
Oner FC, Dvorak M, Vialle L, Aarabi B, Bellabarbra C,
Fehlings MG, Kandziora F. Establishing the Injury Severity
of Thoracolumbar Trauma: Confirmation of the
Hierarchical Structure of the AOSpine Thoracolumbar
Spine Injury Classification System. The Lumbar Spine
Research Society. Chicago, IL, May 2015.
E-poster Presentations:
1. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 Global Spine Congress (GSC) Buenos
Aires, Argentina. May 20-23, 2015.
2. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 American Association of Neurological
Surgeons (AANS) Annual Meeting. Washington DC. May
2-6, 2015.
Presented
Podium Presentations:
1. Fehlings MF, Kopjar B, Grossman R. Efficacy and Safety
of Riluzole in Acute Spinal Cord Injury (SCI). Rationale
and Design of AOSpine Phase III Multi-center Double
Blind Randomized Controlled Trial. (RISCIS). 2013 SRS
20th Annual International Meeting on Advanced Spine
Techniques (IMAST). Vancouver, Canada. July 10-13,
2013.
2. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2014 International Meeting on Advanced Spine
Techniques (IMAST). Valencia, Spain. July 16-19, 2014.
3. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2014 Congress of Neurological Surgeons (CNS)
Meeting. Boston, MA. October 18-22, 2014.
4. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2014 North American Spine Society (NASS)
Meeting. San Francisco, CA. November 12-15, 2014.
5. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 AO ONE Conference. Las Vegas, NV.
February 5-7, 2015.
E-poster Presentations:
1. Fehlings, MF, Kopjar, B, Grossman, R. , Wilson, J.
Efficacy and Safety of Riluzole in Acute Spinal Cord
Injury (SCI). Rationale and Design of AOSpine Phase III
Multi-center Double Blind Randomized Controlled Trial.
(RISCIS). 2015 AANS/CNS Joint Section on Disorders of
the Spine and Peripheral Nerves. Phoenix, Arizona.
March 4-7, 2015.
2. Fehlings, MF, Kopjar, B, Grossman, R. Efficacy and
Safety of Riluzole in Acute Spinal Cord Injury (SCI).
Rationale and Design of AOSpine Phase III Multi-center
Double Blind Randomized Controlled Trial. (RISCIS).
2014 American Association of Neurological Surgeons
(AANS) Annual Meeting. San Francisco, CA. April 5-9,
2014.
3. Fehlings MF, Grossman R, Wilson J, Frankowski R,
Kopjar B, Burau K, Chow D, Tator C, Teng A, Toups E,
Harrop J, Aarabi B, Shaffrey C, Johns M. The Clinical
Translation of Riluzole for the Treatment of Traumatic
Spinal Cord Injury: Design of a Phase II/III Trial. 2013
63rd Annual Meeting of the Congress of Neurological
Surgeons (CNS). San Francisco CA, October 19-23, 2013.
Manuscripts
Submitted
1. Vaccaro, A. R., J. D. Koerner, K. E. Radcliff, F. C. Oner,
M. Reinhold, K. J. Schnake, F. Kandziora, M. G. Fehlings,
M. F. Dvorak, B. Aarabi, S. Rajasekaran, G. D. Schroeder,
C. K. Kepler and L. R. Vialle (2015). "AOSpine subaxial
cervical spine injury classification system." Eur Spine J.
(Accepted)
2. Kepler, C. K., A. R. Vaccaro, J. D. Koerner, M. Dvorak, F.
Kandziora, S. Rajasekaran, L. Vialle, M. Fehlings, G. D.
Schroeder, M. Reinhold, K. Schnake, C. Bellabarba and C.
Oner (2015). "Reliability Analysis of the AOSpine
thoracolumbar Spine Injury Classification System by a
Worldwide Group of Naïve Spinal Surgeouns." European
Spine Journal. (Accepted)
3. Sadiqi S, Lehr AM, Post MW, Vaccaro AR, Dvorak MF,
Oner CF. Towards a specific outcome instrument for spinal
trauma – How to measure function and health. Spine (Phila
Pa 1976). (Accepted)
4. Schroeder GD, Vaccaro AR, Kepler CK, Koerner JD, Oner
FC, Dvorak M, Vialle L, Aarabi B, Bellabarba C, Fehlings
MG, Schnake KJ, Kandziora F. Establishing the Injury
Severity of Thoracolumbar Trauma: Confirmation of the
Hierarchical Structure of the AOSpine Thoracolumbar
Spine Injury Classification system. Spine (Phila Pa 1976).
(Accepted)
5. Schroeder GD, Kepler CK, Koerner JD, Oner FC, Fehlings
MG, Aarabi B, Kandziora F, Vialle L, Vaccaro AR. Can a
Thoracolumbar injury severity score be uniformly applied
from T1 to L5 or are modifications necessary? Global
Spine Journal. (Accepted)
6. Schroeder GD, Kepler CK, Koerner JD, Oner FC, Fehlings
MG, Aarabi B, Marcel D, Reinhold M, Bellabarba C,
Chapman J, Vialle L, Vaccaro AR. A Worldwide Analysis
of the Reliability and Perceived Importance of an Injury to
the Posterior Ligamentous Complex in AO Type A
Fractures. Global Spine Journal. (Accepted)
7. Schroeder GD, Vaccaro AR, "Variations in the treatment of
thoracolumbar burst fractures". Contemporary Spine
Surgery (Accepted)
8. Oner FC, Sadiqi S, Lehr AM, Aarabi B, Dunn, RN, Dvorak
MF, Fehlings MG, Kandziora F, Post MW, Rajasekaran S,
Vialle, LR, Vaccaro AR. Towards developing a specific
outcome instrument for spine trauma; An empirical crosssectional multicentre ICF-based study by AOSpine
Knowledge Forum Trauma. Spine (Phila Pa 1976). (In
review)
9. Schroeder GD, Kepler CK, Koerner JD, Chapman J,
Bellabarba C, Oner FC, Reinhold M, Dvorak M, Aarabi B,
Vialle L, Fehlings MG, Rajasekaran S, Kandziora F,
Vaccaro AR. Is there a regional difference in morphology
interpretation of A3/A4 fractures among
cultures? The Spine Journal. (In review)
different
10. Kepler CK, Vaccaro AR, Schroeder GD, Koerner JD,
Vialle L, Aarabi B, Rajasekaran S, Bellabarba C, Chapman
J, Kandziora F, Dvorak M, Reinhold M, Oner FC . The
Thoracolumbar AOSpine Injury Score (TL AOSIS). Spine
(Phila Pa 1976). (In review)
11. Vaccaro AR, Schroeder GD, Kepler CK, Oner F.C, Vialle
L, Kandziora F, Koerner JD, Kurd MF, Reinhold M,
Schnake KJ, Chapman J, Aarabi B, Fehling MG, Dvorak
M, “The Surgical Algorithm for the AOSpine
Thoracolumbar Spine Injury Classification System” The
European Spine Journal (In Review)
12. Fehlings MF, Nakashima H, Nagoshi N, Chow DSL,
Grossman RG, Kopjar B. "The Riluzole in Acute Spinal
Cord Injury (RISCIS): Rationale, Design and Critical
Endpoints". Spinal Cord (In Review)
13. Chaudhary, B. R., M. Fehlings, L. Vialle, K. Schnake, C.
K. Kepler, J. D. Koerner, M. Dvorak, F. Kandziora, S.
Rajasekaran, B. Aarabi, G. D. Schroeder, M. Reinhold, C.
Bellabarba, C. Oner and A. R. Vaccaro "The AO Spine
Thoracolumbar Spine Injury Classification System: The
ability of Surgeons to Correctly Classify Different Fracture
Subtypes." Spine (Phila Pa 1976). (In Review)
14. Geuze, R. E., D. H. R. Kempen, P. de Baat, S. P. J. Mujis,
A. M. Lehr, S. Rajasekaran, F. Kandziora, A. R. Vaccaro
and C. Oner "Regional variations in treatment of thoracic
and lumbar burst fractures, a review of recent
literature." Spine (Phila Pa 1976). (In Review)
15. Sadiqi, S., C. Oner, M. Dvorak, B. Aarabi, G. D. Schroeder
and A. R. Vaccaro "The influence of spine surgeons'
experience on the classification and intraobserver reliability
of the novel AOSpine Thoracolumbar Spine Injury
Classification System - an international study." Spine
(Phila Pa 1976). (In Review)
16. Oner, F. C., W. C. H. Jacobs, A. M. Lehr, S. Sadiqi, M. W.
Post, B. Aarabi, J. Chapman, M. Dvorak, M. Fehlings, F.
Kandziora, S. Rajasekaran and A. R. Vaccaro. "Towards
the development of a universal outcome instrument for
spine trauma - A systematic review and content comparison
of outcome measures used in spine trauma research using
the ICF as reference." Spine (Phila Pa 1976). (In Review)
17. Kepler CK, Vaccaro AR, Fleischmna AN, Traynelis
VC, Patel AA, Dekutoski MB, Harrop J, Wood KB,
Schroeder GD, Bransford R, Aarabi, N, Okonowo DO,
Arnold PM, Fehlings MG, Nassr A, Shaffrey C, Yoon ST,
Kwon B. “Treatment of Axis Body Fractures: A
Systematic Review” The Journal of Spinal Disorders
and Techniques. (In Review)
Published
1. Oner, F. C., S. Sadiqi, A. M. Lehr, M. F. Dvorak, B.
Aarabi, J. R. Chapman, M. G. Fehlings, F. Kandziora, S.
Rajasekaran and A. R. Vaccaro (2015). "Towards the
development of an outcome instrument for spinal trauma:
an international survey of spinal surgeons." Spine (Phila Pa
1976) 40(2): E91-96.
2. Vaccaro, A. R., C. Oner, C. K. Kepler, M. Dvorak, K.
Schnake, C. Bellabarba, M. Reinhold, B. Aarabi, F.
Kandziora, J. Chapman, R. Shanmuganathan, M. Fehlings,
L. Vialle, A. O. S. C. Injury and F. Trauma Knowledge
(2013). "AOSpine thoracolumbar spine injury classification
system: fracture description, neurological status, and key
modifiers." Spine (Phila Pa 1976) 38(23): 2028-2037.
3. Fehlings, M. G., J. R. Wilson, R. F. Frankowski, E. G.
Toups, B. Aarabi, J. S. Harrop, C. I. Shaffrey, S. J.
Harkema, J. D. Guest, C. H. Tator, K. D. Burau, M. W.
Johnson and R. G. Grossman (2012). "Riluzole for the
treatment of acute traumatic spinal cord injury: rationale for
and design of the NACTN Phase I clinical trial." J
Neurosurg Spine 17(1 Suppl): 151-156.
4. Tator, C. H., R. Hashimoto, A. Raich, D. Norvell, M. G.
Fehlings, J. S. Harrop, J. Guest, B. Aarabi and R. G.
Grossman (2012). "Translational potential of preclinical
trials of neuroprotection through pharmacotherapy for
spinal cord injury." J Neurosurg Spine 17(1 Suppl): 157229.
Book Chapters
1. GD. Schroeder and AR. Vaccaro. Cervical Spine Trauma.
2nd Ed. for Handbook of Spine Surgery. New York.
Thieme. In Press
2. BI. Woods, GD. Schroeder, AR. Vaccaro. Fractures and
dislocations of the cervical spine from C-3 to C-7.
Chapman's Orthopaedic Surgery, 4th Edition Publisher:
Lippincott Williams & Wilkins. In press
3. JD. Koerner, AR. Vaccaro. Evaluation and Classification
and Treatment of Cervical (C3-C7) Injuries. In HR. Winn
(Ed.), Youmans Neurological Surgery, 7th Edition.
Philadelphia PA. Elsevier. In press
4. P. Kumar, BA and K. Lau, P. Millhouse, CK. Kepler, AR.
Vaccaro. New classification and management of
thoracolumbar spine injury. Techniques in Spine Surgery.
Seoul. Springer Korea Limited. In Press.
5. GD. Schroeder, PW Millhouse, AR Vaccaro, FC
Oner. The AOSpine Subaxial Cervical Classification
System. In Vialle LR, Oner FC, Vaccaro AR ed. In
LR.Vialle, KD. Riew & M. Ito (Eds.), AOSpine Masters
Series Volume 4. New York: Thieme.
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