1. No category

***ABDO A. ELFIKY***
16 Alkhalifa Almamoon St. from Mostafa Elmasry St. Maryotia, Faysal,
Giza, Egypt.
Telephone: + 202 33823995
Mobile: + 2 01115121528
E-mail: [email protected]
EDUCATION &WORK EXPERIENCE

Postdoctoral fellow at Biochemistry and Structural Biology Department, Lund
University, Lund, Sweden. (March – September 2015).

Ph.D. in Molecular Biophysics, Biophysics Department, faculty of science, Cairo
University. (August 2013).

M.Sc. in Molecular Biophysics, Biophysics Department, faculty of science, Cairo
University. (March 2010)

B.Sc. in Biophysics, Biophysics Department, Faculty of Science, Cairo University.
Accumulated Grade: Excellent with honor, ranked as 2nd among the Biophysics
Department. (May 2007)

Working as Lecturer at Biophysics Department, Faculty of Science, Cairo University
(September 2013 till now).

Principle Investigator in a project funded by Cairo University, Faculty of Science
entitled “Exploring the effect of mutations on the reactivity of HCV NS5B
Nucleotide Inhibitor (2′-Methylguanosine) for Egypt prevalent subtype 4a” (May
2014 till now).

Participated as a researcher in a project from cairo University entitled "Molecular
modeling approach for the design and evaluation of Hepatitis C Virus inhibitors"
(Nov 2011 – Nov 2013).

Participated with a poster in “Advanced workshop on Structural Biology: Using
Synchrotron radiation to visualize Biological Molecules” held by International
Centre for Theoretical Physics (ICTP) Trieste, Italy 15-20 December 2014.

Attended a scientific seminar entitled “Stem Cell Behaviour in Development,
Reparative and Regenerative Medicine: Balance is better than Imbalance.” Held at
department of Zoology, Faculty of Science, Cairo University Nov. 2014.

Invited speaker in “Recent trends in Biophysics” coordinated by the National
Comitte for Pure and Applied Biophysics in Cairo University New Central Library
entitled “Molecular Modeling applications on Hepatitis C Virus” 10/9/2014.

Participated in " Third LinkSCEEM General User Meeting" [Structural and
Computational Biophysics group] held at Bibliotheca Alexandrina, Egypt. (25-27 June
2013).

Participated in " Third LinkSCEEM cross-sectional HPC workshop" [Structural and
Computational Biophysics group] held at Faculty of Computers and Information Cairo University (FCI-CU) & American University in Cairo (AUC) Egypt from 11 to
15 November 2012).

Organized and Participated in the "School of Structural Bioinformatics" held at
Cairo university by collaboration between Biophysics department, Cairo University,
Egypt & Biochemistry and Structral biology department, Lund University, Sweden.
(29th September – 04th October 2012).

Participated in "From genes to atomic structures: An introduction to synchrotronbased structural biology" activity in International Center for theoretical physics
(ICTP) from 23-27 April 2012, Trieste, Italy.

Participated with a poster in XV School for pure and applied biophysics entitled
"Protein stability and pathways of self-assembly". Held in Istituto Veneto
diScienzeeLettere ed Arti Venice, Italy (24-28 January 2011).

Award "Graduate Research Challenge Fund" GRCF from Faculty of Science, Cairo
University , ranked 1st among the faculty demonstrators. (January 2009)

Participated in SESAME workshop held in Cairo University, attend the practical
session for protein crystallization. (November 2008)

Worked as Assistant Lecturer at Biophysics Department, Faculty of Science, Cairo
University (June 2010 till August 2013).
 Worked as a Demonstrator at Biophysics Department, Faculty of Science, Cairo
University (January 2008 till May 2010).
RESEARCH EXPERIENCES

In my M.Sc. research work I have studied the correlation between protein structure
folding and Wide Angle X-ray Scattering (WAXS) signatures and suggest WAXS as a
tool to investigate protein structure folding changes. Also I suggest WAXS generated
in silico as a tool that can be used in protein model validation.
 In my Ph.D. work I used Molecular modeling, QSAR, computational chemistry and
protein modeling to study the difference in the interactions between HCV NS5B
polymerase from different genotypes with different drugs some of which currently
2
used and other drugs in clinical trials phase II or III.
EDITORIAL BOARD
Journal of Computational Simulation and Modeling (bioinfo bublications)
JOURNAL REVIEWER
Current Computer Aided Drug Design (Bentham).
Medicinal chemistry research (Springer).
SAR and QSAR in environmental research (Taylor & Francis).
PERSONAL INFORMATION
Date of Birth:
11/06/1986
Marital Status: Married.
Military Status: Exempted.
PUBLICATIONS
1. Wael M Elshemey, Abdo A Elfiky and Wissam A Gawad (2010) Correlation to
protein conformation of Wide-Angle X-ray Scattering Parameters. Protein Journal
29:545-550.
2. Abdo A Elfiky, Wael M Elshemey, Wissam A Gawad and Omar S Desoky (2013)
Molecular Modeling Comparison of the Performance of NS5b Polymerase
Inhibitor (PSI-7977) on Prevalent HCV Genotypes. Protein Journal 32(1):75-80.
3. Noha A Saleh, Abdo A Elfiky, Ahmed A Ezat, Wael M Elshemey, and Medhat
Ibraheim (2014) The Electronic and QSAR Properties of Modified Telaprevir
Compounds as HCV NS3 protease inhibitors. Journal of Computational and
Theoretical Nanoscience 11(2), 544-548.
4. Abdo A Elfiky, Wael M Elshemey and Wissam A Gawad (2015) 2′Methylguanosine prodrug (IDX-184), Phosphoramidate prodrug (Sofosbuvir),
Diisobutyryl prodrug (R7128) are better than their parent nucleotides and
Ribavirin in HCV inhibition: A Molecular Modeling study Journal of
Computational and Theoretical Nanoscience 12(3), 376-386.
5. Noha A Saleh, Ahmed A Ezat, Abdo A Elfiky, Wael M Elshemey, and Medhat
Ibraheim Theoretical Study on Modified Boceprevir Compounds as NS3 protease
inhibitors Journal of Computational and Theoretical Nanoscience 12(3), 371-375.
REGISTERED MASTER DERGREE SUPERVISION
Reactivity of Nucleotide Inhibitors on the Polymerases of Archaeological Virus Dec. 2014 (M.Sc.)
COMPUTER AND LANGUAGE SKILLS

ICDL.
3
 TEOFL iBT 73
 C++ programming experience.
 Experience in protein modeling software, structural analysis and validation
programs,
CRYSOL, COOT, VMD and computational chemisty programs
SCIGRESS and GAUSIAN.
COURSES TAUGHT









Molecular Biophysics.
Computational biophysics.
Biophysical measurements.
Molecular Spectroscopy.
Bioinformatics.
Biostatistics.
Radiobiology.
Radiation Biophysics.
Bioenergetics.
REFRENCES
1. Prof. Dr. Wael M. Elshemey
E-mail: [email protected]
Tele. : 00 202 0101560029
2. Dr. Mohsen M. Mady
E-mail: [email protected]
Tele. : 00966597121727
3. Dr. Ismail H Ismail
E-mail: [email protected]
4