1. science
2. ecology
3. waste management
4. waste disposal

MSDS# 5148 COVER SHEET
89855
Active Ras Pull-Down
and Detection Kit
Component #
89855A
Description
Glutathione Resin
89855B
2X SDS Sample Buffer
89855C
Lysis/Binding/Wash Buffer
89855D
Anti-Ras Antibody
89855E
GST-Raf1-RBD
89855F
GDP (100 mM)
89855G
GTP-Gamma-S (10 mM)
Pierce
PO BOX 117
(815) 968-0747
3747 N. Meridian Road
Rockford, IlL 61105
(815) 968-7316 fax
www.thermo.com
Part of Thermo Fisher Scientific
Glutathione Resin
2.
Material Safety Data Sheet
1.
Product and company identification
: Glutathione Resin
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
2.
Manufacturer
: Thermo Fisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600
877.886.7629
Emergency overview
: 26185A 26186A 26187A 78380 89854A 89855A 89856A 89857A 89872A 1900332
1900296
: 2773
: 10/14/2008.
: 10/14/2008.
: MSDS Specialist
: CHEMTREC: Use of
: Refer to the instruction booklet for
proper and intended use.
800.424.9300 Substance/Preparation
Otherwise, contact supplier for
OUTSIDE US:
specific applications.
202.483.7616
Eyes
Medical conditions
aggravated by overexposure
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: Irritating to respiratory system. Exposure to decomposition products may cause a health
hazard. Serious effects may be delayed following exposure.
: No known significant effects or critical hazards.
Ingestion
: Irritating to skin.
Skin
: Irritating to eyes.
Eyes
Potential chronic health effects
Chronic effects
: Contains material that can cause target organ damage.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
1/8
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
Contains material which causes damage to the following organs: the reproductive
system.
Contains material which does not cause damage to the following organs: central nervous
system (CNS).
: No specific data.
: Adverse symptoms may include the following:
irritation
redness
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Ingestion
Skin
: Liquid. [Suspension.]
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
: WARNING !
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS
MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
Irritating to eyes, respiratory system and skin. Avoid exposure - obtain special
instructions before use. Do not breathe vapor or mist. Avoid contact with eyes, skin and
clothing. Contains material that can cause target organ damage. Use only with
adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash
thoroughly after handling.
10/14/2008.
:
:
:
:
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
Hazards identification
Physical state
OSHA/HCS status
Hazards identification
Teratogenicity
Developmental effects
Fertility effects
Target organs
: Pre-existing disorders involving any target organs mentioned in this MSDS as being at
risk may be aggravated by over-exposure to this product.
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
3.
Composition/information on ingredients
United States
Name
Glutathione
CAS number
70-18-8
Europe
Substance/preparation
Ingredient name
%
1-3
: Preparation
CAS
number
70-18-8
Glutathione
%
EC number
1-3
200-725-4
Classification
[1]
Xn; R68
Xi; R36/37
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
Occupational exposure limits, if available, are listed in section 8.
2/8
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Glutathione Resin
4.
Glutathione Resin
6.
First aid measures
: Move exposed person to fresh air. If it is suspected that fumes are still present, the
rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep
person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest
occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous
to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention.
If unconscious, place in recovery position and get medical attention immediately.
Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.
In case of inhalation of decomposition products in a fire, symptoms may be delayed.
The exposed person may need to be kept under medical surveillance for 48 hours.
Inhalation
Ingestion
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention. Never give anything by mouth to an
unconscious person. If unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen tight clothing such as a collar,
tie, belt or waistband.
Skin contact
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Continue to rinse for at least 10 minutes. Get medical attention. Wash clothing
before reuse. Clean shoes thoroughly before reuse.
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention.
: No action shall be taken involving any personal risk or without suitable training. If it is
suspected that fumes are still present, the rescuer should wear an appropriate mask or
self-contained breathing apparatus. It may be dangerous to the person providing aid to
give mouth-to-mouth resuscitation.
Eye contact
Protection of first-aiders
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Large spill
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
Small spill
7.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store between the following temperatures: 2 to 8°C (35.6 to 46.4°F). Store in
accordance with local regulations. Store in original container protected from direct
sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see
section 10) and food and drink. Keep container tightly closed and sealed until ready for
use. Containers that have been opened must be carefully resealed and kept upright to
prevent leakage. Do not store in unlabeled containers. Use appropriate containment to
avoid environmental contamination.
See section 11 for more detailed information on health effects and symptoms.
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Hazardous combustion
products
Special protective
equipment for fire-fighters
: In a fire or if heated, a pressure increase will occur and the container may burst.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: Decomposition products may include the following materials:
carbon oxides
nitrogen oxides
sulfur oxides
8.
Exposure controls/personal protection
Europe
No exposure limit value known.
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
3/8
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor
or mist, use process enclosures, local exhaust ventilation or other engineering controls
to keep worker exposure to airborne contaminants below any recommended or statutory
limits.
4/8
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Glutathione Resin
8.
Glutathione Resin
Exposure controls/personal protection
Hygiene measures
11 . Toxicological information
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Recommended: Respirator selection must be based on known or anticipated exposure
levels, the hazards of the product and the safe working limits of the selected respirator.
Respiratory
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
1-4 hours (breakthrough time): disposable vinyl
Hands
Eyes
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Recommended: safety glasses with side-shields
Skin
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Recommended: lab coat
Environmental exposure
controls
Personal protective
equipment (Pictograms)
9.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Possibility of hazardous
reactions
IARC
-
EPA
-
NIOSH
None.
NTP
-
OSHA
None.
: Not available.
: Not available.
: Not available.
Europe
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
:
:
:
:
:
:
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
: Will not occur.
5/8
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: No known significant effects or critical hazards.
: Not available.
13 . Disposal considerations
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
10/14/2008.
Biosciences Division
Pierce
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Conclusion/Summary
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
10 . Stability and reactivity
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Chronic toxicity
Conclusion/Summary
: Not available.
Carcinogenicity
Conclusion/Summary
: Not available.
Classification
Product/ingredient name
ACGIH
glycine, n-(n-l-?-glutamyl-l-cysteinyl)-
12 . Ecological information
: Liquid. [Suspension.]
: Insoluble in the following materials: cold water and hot water.
Chemical stability
: To the best of our knowledge, the toxicological properties of this product have not been
thoroughly investigated.
:
Physical and chemical properties
Physical state
Solubility
United States
Acute toxicity
Conclusion/Summary
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Hazardous waste
6/8
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Glutathione Resin
Glutathione Resin
14 . Transport information
16 . Other information
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
DOT Classification
Not
regulated.
-
-
-
IATA-DGR Class
Not
regulated.
-
-
-
The customer is responsible for determining the PPE code for this material.
National Fire Protection
:
Association (U.S.A.)
Health
15 . Regulatory information
U.S. Federal regulations
International regulations
International lists
0
Instability
Date of printing
: Irritating material
Target organ effects
: United States inventory (TSCA 8b): All components are listed or exempted.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
: Class D-2A: Material causing other toxic effects (Very toxic).
: Canada inventory: All components are listed or exempted.
: 10/14/2008.
: 10/14/2008.
Date of issue
Date of previous issue
: No previous validation.
Version
: 1
Indicates information that has changed from previously issued version.
Full text of R-phrases
: R68- Possible risk of irreversible effects.
R36/37- Irritating to eyes and respiratory system.
referred to in sections 2 and
3 - Europe
Full text of classifications
: Xn - Harmful
Xi - Irritant
referred to in sections 2 and
3 - Europe
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
: This product is not classified according to EU legislation.
:
Risk phrases
2
Special
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
Canada
WHMIS (Canada)
Canada inventory
EU regulations
Flammability
0
PG* : Packing group
United States
HCS Classification
0
Physical hazards
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): Not determined.
16 . Other information
Label requirements
Hazardous Material
Information System (U.S.A.)
: CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS
MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
:
Health
2
Flammability
0
7/8
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
8/8
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Part of Thermo Fisher Scientific
2X SDS Sample Buffer
2.
Material Safety Data Sheet
1.
Product and company identification
: 2X SDS Sample Buffer
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
2.
:
:
:
:
:
:
Manufacturer
: Thermo Fisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600
877.886.7629
26185B 26186B 26187B 89854B 89855B 89856B 89857B
4084
10/28/2008.
10/28/2008.
MSDS Specialist
CHEMTREC: Use of
: Refer to the instruction booklet for
proper and intended use.
800.424.9300 Substance/Preparation
Otherwise, contact supplier for
OUTSIDE US:
specific applications.
202.483.7616
Emergency overview
: Liquid.
: Odorless.
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
: WARNING !
HARMFUL IF INHALED. CAUSES RESPIRATORY TRACT, EYE AND SKIN
IRRITATION. MAY BE HARMFUL IF ABSORBED THROUGH SKIN OR IF
SWALLOWED. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN
DAMAGE.
Toxic by inhalation. Harmful in contact with skin and if swallowed. Irritating to eyes,
respiratory system and skin. Avoid exposure - obtain special instructions before use.
Do not breathe vapor or mist. Do not ingest. Do not get in eyes. Avoid contact with skin
and clothing. Contains material that can cause target organ damage. Use only with
adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash
thoroughly after handling.
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: Toxic by inhalation. Irritating to respiratory system. Exposure to decomposition products
may cause a health hazard. Serious effects may be delayed following exposure.
: Harmful if swallowed.
Ingestion
: Harmful in contact with skin. Irritating to skin.
Skin
: Irritating to eyes.
Eyes
Potential chronic health effects
1/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
:
:
:
:
:
:
:
Contains material that can cause target organ damage.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
Contains material which causes damage to the following organs: kidneys, lungs, mucous
membranes, gastrointestinal tract, upper respiratory tract, skin, eye, lens or cornea.
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
: No specific data.
: Adverse symptoms may include the following:
irritation
redness
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Ingestion
Skin
Eyes
Medical conditions
aggravated by overexposure
Hazards identification
Physical state
Odor
OSHA/HCS status
Hazards identification
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
Target organs
: Pre-existing respiratory, skin and digestive disorders and disorders involving any other
target organs mentioned in this MSDS as being at risk may be aggravated by overexposure to this product.
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
3.
Composition/information on ingredients
United States
Name
Sodium Dodecyl Sulfate
Glycerol
Tris Base BioGrade
Europe
Substance/preparation
Ingredient name
CAS number
151-21-3
56-81-5
77-86-1
%
3-5
1-3
1-3
: Preparation
CAS
number
151-21-3
%
EC number
Classification
Sodium Dodecyl Sulfate
3-5
205-788-1
Glycerol
56-81-5
1-3
200-289-5
Tris Base BioGrade
77-86-1
1-3
201-064-4
Xn; R22
N; R50
Xi;
R36/37/38
Xn;
R20/21/22
[1]
[1] [2]
[1]
2/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
2X SDS Sample Buffer
3.
2X SDS Sample Buffer
Composition/information on ingredients
5.
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
Occupational exposure limits, if available, are listed in section 8.
4.
First aid measures
: Get medical attention immediately. Move exposed person to fresh air. If it is suspected
that fumes are still present, the rescuer should wear an appropriate mask or selfcontained breathing apparatus. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. It may be dangerous to the person providing aid to give mouth-tomouth resuscitation. If unconscious, place in recovery position and get medical attention
immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or
waistband. In case of inhalation of decomposition products in a fire, symptoms may be
delayed. The exposed person may need to be kept under medical surveillance for 48
hours.
Inhalation
Ingestion
: Get medical attention immediately. Wash out mouth with water. Remove dentures if
any. Move exposed person to fresh air. Keep person warm and at rest. If material has
been swallowed and the exposed person is conscious, give small quantities of water to
drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not
induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the
head should be kept low so that vomit does not enter the lungs. Never give anything by
mouth to an unconscious person. If unconscious, place in recovery position and get
medical attention immediately. Maintain an open airway. Loosen tight clothing such as
a collar, tie, belt or waistband.
Skin contact
: Get medical attention immediately. Flush contaminated skin with plenty of water.
Remove contaminated clothing and shoes. Wash contaminated clothing thoroughly with
water before removing or wear gloves. Continue to rinse for at least 10 minutes. Wash
clothing before reuse. Clean shoes thoroughly before reuse.
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention.
: No action shall be taken involving any personal risk or without suitable training. If it is
suspected that fumes are still present, the rescuer should wear an appropriate mask or
self-contained breathing apparatus. It may be dangerous to the person providing aid to
give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water
before removing or wear gloves.
Eye contact
Protection of first-aiders
See section 11 for more detailed information on health effects and symptoms.
5.
Fire-fighting measures
Hazardous combustion
products
: Decomposition products may include the following materials:
carbon oxides
nitrogen oxides
sulfur oxides
metal oxide/oxides
Special protective
equipment for fire-fighters
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
6.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Large spill
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
Small spill
7.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
: In a fire or if heated, a pressure increase will occur and the container may burst.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
3/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
4/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
2X SDS Sample Buffer
2X SDS Sample Buffer
8.
8.
Exposure controls/personal protection
Product name
United States
glycerol
Exposure limits
ACGIH (United States, 0/2000).
TWA: 10 mg/m³
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
OSHA PEL (United States).
TWA: 15 mg/m³ 8 hour(s). Form: Total dust
ACGIH TLV (United States, 1/2008).
TWA: 10 mg/m³ 8 hour(s). Form: Mist
OSHA PEL 1989 (United States, 3/1989).
TWA: 10 mg/m³ 8 hour(s). Form: Total dust
TWA: 5 mg/m³ 8 hour(s). Form: Respirable fraction
OSHA PEL (United States, 11/2006).
TWA: 15 mg/m³ 8 hour(s). Form: Total dust
TWA: 5 mg/m³ 8 hour(s). Form: Respirable fraction
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
OSHA PEL (United States).
TWA: 15 mg/m³ 8 hour(s). Form: Total dust
OSHA (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³
TWA: 5 mg/m³
ACGIH TLV (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
OSHA PEL 1989 (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
Exposure controls/personal protection
Respiratory
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Hands
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Eyes
Skin
Environmental exposure
controls
9.
Physical and chemical properties
Physical state
Color
Odor
Dispersibility properties
Solubility
:
:
:
:
:
Liquid.
Purple.
Odorless.
Dispersible in the following materials: cold water and hot water.
Soluble in the following materials: cold water and hot water.
10 . Stability and reactivity
Europe
glycerol
Chemical stability
ACGIH (United States, 0/2000).
TWA: 10 mg/m³
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
TWA: 10 mg/m³ 8 hour(s). Form: Mist
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
ACGIH TLV (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure to airborne contaminants below any
recommended or statutory limits.
Hygiene measures
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Possibility of hazardous
reactions
United States
Acute toxicity
Product/ingredient name
sodium dodecyl sulfate
1,3-propanediol, 2-amino-25/10
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: Will not occur.
11 . Toxicological information
Personal protection
10/28/2008.
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
Result
LD50
Intraperitoneal
LD50 Intravenous
LD50 Oral
LDLo Dermal
LC50 Inhalation
Dusts and mists
LD50 Intravenous
Species
Rat
Dose
210 mg/kg
Exposure
-
Rat
Rat
Rabbit
Rat
118 mg/kg
1288 mg/kg
10 gm/kg
>3900 mg/m3
1 hours
Rat
1800 mg/kg
6/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
2X SDS Sample Buffer
2X SDS Sample Buffer
11 . Toxicological information
12 . Ecological information
(hydroxymethyl)LD50 Oral
LD50 Oral
LDLo Oral
LD50 Dermal
LD50
Intraperitoneal
LD50 Intravenous
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50
Subcutaneous
LDLo
Intramuscular
TDLo
Intramuscular
TDLo
Intramuscular
glycerol
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
Carcinogenicity
Conclusion/Summary
Classification
Product/ingredient name
sodium dodecyl sulfate
glycerol
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Conclusion/Summary
Rat
Rat
Rabbit
Rabbit
Rat
5900 mg/kg
5900 mg/kg
1000 mg/kg
>10 gm/kg
4420 mg/kg
-
Rat
Guinea pig
Mouse
Mouse
Rat
Rat
Rat
Rat
Rat
5566 mg/kg
7750 mg/kg
4090 mg/kg
4090 mg/kg
12600 mg/kg
12600 mg/kg
12600 mg/kg
12600 mg/kg
100 mg/kg
-
Rat
10 mg/kg
-
Rat
5000 mg/kg
-
Rat
8 mL/kg
-
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
Other adverse effects
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Hazardous waste
14 . Transport information
: Not available.
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
: Not available.
DOT Classification
Not
regulated.
-
-
-
: Not available.
IATA-DGR Class
Not
regulated.
-
-
-
ACGIH
A2
-
IARC
-
EPA
-
NIOSH
None.
None.
NTP
-
OSHA
None.
-
PG* : Packing group
15 . Regulatory information
United States
HCS Classification
: Not available.
: Not available.
U.S. Federal regulations
: Not available.
:
:
:
:
:
:
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
7/10
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
: Toxic material
Irritating material
Target organ effects
: United States inventory (TSCA 8b): All components are listed or exempted.
TSCA 8(d) H and S data reporting: glycerol
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: glycerol; sodium dodecyl sulfate
SARA 311/312 MSDS distribution - chemical inventory - hazard identification:
glycerol: Immediate (acute) health hazard, Delayed (chronic) health hazard; sodium
dodecyl sulfate: Immediate (acute) health hazard, Delayed (chronic) health hazard
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
10/28/2008.
Biosciences Division
Pierce
: Not available.
: No known significant effects or critical hazards.
13 . Disposal considerations
Europe
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
: No known significant effects or critical hazards.
www.thermo.com/pierce
8/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
2X SDS Sample Buffer
2X SDS Sample Buffer
15 . Regulatory information
16 . Other information
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
Canada
WHMIS (Canada)
Canadian lists
Canada inventory
EU regulations
Full text of R-phrases
: R22- Harmful if swallowed.
R20/21/22- Harmful by inhalation, in contact with skin and if swallowed.
referred to in sections 2 and
R36/37/38- Irritating to eyes, respiratory system and skin.
3 - Europe
R50- Very toxic to aquatic organisms.
: Xn - Harmful
Full text of classifications
Xi - Irritant
referred to in sections 2 and
N - Dangerous for the environment
3 - Europe
: Class D-2B: Material causing other toxic effects (Toxic).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
: Canada inventory: All components are listed or exempted.
: This product is not classified according to EU legislation.
:
Risk phrases
International regulations
International lists
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): All components are listed or exempted.
16 . Other information
Label requirements
: HARMFUL IF INHALED. CAUSES RESPIRATORY TRACT, EYE AND SKIN
IRRITATION. MAY BE HARMFUL IF ABSORBED THROUGH SKIN OR IF
SWALLOWED. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN
DAMAGE.
Hazardous Material
Information System (U.S.A.)
:
Health
2
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
Flammability
0
Health
2
0
Instability
Special
Date of printing
: 10/28/2008.
: 10/28/2008.
Date of issue
Date of previous issue
: 10/14/2008.
Version
: 1.01
Indicates information that has changed from previously issued version.
9/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
10/10
10/28/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Part of Thermo Fisher Scientific
Lysis/Binding/Wash Buffer
2.
Material Safety Data Sheet
1.
Product and company identification
: Lysis/Binding/Wash Buffer
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
2.
:
:
:
:
:
:
Manufacturer
: Thermo Fisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600
877.886.7629
Emergency overview
26185C 26186C 26187C 89854C 89855C 89856C 89857C 89872C
6820
10/14/2008.
10/14/2008.
MSDS Specialist
CHEMTREC: Use of
: Refer to the instruction booklet for
proper and intended use.
800.424.9300 Substance/Preparation
Otherwise, contact supplier for
OUTSIDE US:
specific applications.
202.483.7616
Eyes
Medical conditions
aggravated by overexposure
: Liquid.
: Odorless.
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
: WARNING !
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS
MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
Irritating to eyes, respiratory system and skin. Avoid exposure - obtain special
instructions before use. Do not breathe vapor or mist. Avoid contact with eyes, skin and
clothing. Contains material that can cause target organ damage. Use only with
adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash
thoroughly after handling.
(815) 968-0747
(815) 968-7316 Fax
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
3.
Composition/information on ingredients
United States
Name
Glycerol
NP-40
CAS number
56-81-5
9036-19-5
Europe
Substance/preparation
Ingredient name
%
3-5
0.1 - 1
: Preparation
CAS
number
56-81-5
%
EC number
3-5
200-289-5
Classification
[1] [2]
Xi;
R36/37/38
[1]
NP-40
9036-19-5 0.1 - 1
Xi;
R36/37/38
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
Occupational exposure limits, if available, are listed in section 8.
1/9
Rockford, IL
61105
: Pre-existing disorders involving any target organs mentioned in this MSDS as being at
risk may be aggravated by over-exposure to this product.
Glycerol
10/14/2008.
3747 N. Meridian Rd.
PO Box 117
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
Contains material which causes damage to the following organs: kidneys, mucous
membranes, gastrointestinal tract, upper respiratory tract, skin, eye, lens or cornea.
: No specific data.
: Adverse symptoms may include the following:
irritation
redness
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Ingestion
Skin
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: Irritating to respiratory system.
: No known significant effects or critical hazards.
Ingestion
: Irritating to skin.
Skin
: Irritating to eyes.
Eyes
Potential chronic health effects
Chronic effects
: Contains material that can cause target organ damage.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Biosciences Division
Pierce
:
:
:
:
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
Hazards identification
Physical state
Odor
OSHA/HCS status
Hazards identification
Teratogenicity
Developmental effects
Fertility effects
Target organs
www.thermo.com/pierce
2/9
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Lysis/Binding/Wash Buffer
4.
Lysis/Binding/Wash Buffer
6.
First aid measures
: Move exposed person to fresh air. If it is suspected that fumes are still present, the
rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep
person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest
occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous
to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention.
If unconscious, place in recovery position and get medical attention immediately.
Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.
Inhalation
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention. Never give anything by mouth to an
unconscious person. If unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen tight clothing such as a collar,
tie, belt or waistband.
Ingestion
Skin contact
Eye contact
Protection of first-aiders
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Continue to rinse for at least 10 minutes. Get medical attention. Wash clothing
before reuse. Clean shoes thoroughly before reuse.
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention.
: No action shall be taken involving any personal risk or without suitable training. If it is
suspected that fumes are still present, the rescuer should wear an appropriate mask or
self-contained breathing apparatus. It may be dangerous to the person providing aid to
give mouth-to-mouth resuscitation.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Large spill
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
Small spill
7.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
See section 11 for more detailed information on health effects and symptoms.
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Hazardous combustion
products
Special protective
equipment for fire-fighters
: In a fire or if heated, a pressure increase will occur and the container may burst.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: Decomposition products may include the following materials:
carbon oxides
8.
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
3/9
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Exposure controls/personal protection
Product name
United States
glycerol
Exposure limits
ACGIH (United States, 0/2000).
TWA: 10 mg/m³
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
OSHA PEL (United States).
TWA: 15 mg/m³ 8 hour(s). Form: Total dust
ACGIH TLV (United States, 1/2008).
TWA: 10 mg/m³ 8 hour(s). Form: Mist
OSHA PEL 1989 (United States, 3/1989).
TWA: 10 mg/m³ 8 hour(s). Form: Total dust
TWA: 5 mg/m³ 8 hour(s). Form: Respirable fraction
4/9
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Lysis/Binding/Wash Buffer
8.
Lysis/Binding/Wash Buffer
Exposure controls/personal protection
8.
OSHA PEL (United States, 11/2006).
TWA: 15 mg/m³ 8 hour(s). Form: Total dust
TWA: 5 mg/m³ 8 hour(s). Form: Respirable fraction
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
OSHA PEL (United States).
TWA: 15 mg/m³ 8 hour(s). Form: Total dust
OSHA (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³
TWA: 5 mg/m³
ACGIH TLV (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
OSHA PEL 1989 (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
Europe
glycerol
Environmental exposure
controls
9.
Chemical stability
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Possibility of hazardous
reactions
Eyes
United States
Acute toxicity
Product/ingredient name
glycerol
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
5/9
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Liquid.
Colorless.
Odorless.
Dispersible in the following materials: cold water and hot water.
Soluble in the following materials: cold water and hot water.
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
: Will not occur.
11 . Toxicological information
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Hands
:
:
:
:
:
10 . Stability and reactivity
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor
or mist, use process enclosures, local exhaust ventilation or other engineering controls
to keep worker exposure to airborne contaminants below any recommended or statutory
limits.
Personal protection
Respiratory
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Physical and chemical properties
Physical state
Color
Odor
Dispersibility properties
Solubility
ACGIH (United States, 0/2000).
TWA: 10 mg/m³
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
TWA: 10 mg/m³ 8 hour(s). Form: Mist
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
ACGIH TLV (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
Hygiene measures
Exposure controls/personal protection
Skin
Result
LD50 Dermal
LD50
Intraperitoneal
LD50 Intravenous
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50
Subcutaneous
LDLo
Intramuscular
TDLo
Intramuscular
TDLo
Intramuscular
Species
Rabbit
Rat
Dose
>10 gm/kg
4420 mg/kg
Exposure
-
Rat
Guinea pig
Mouse
Mouse
Rat
Rat
Rat
Rat
Rat
5566 mg/kg
7750 mg/kg
4090 mg/kg
4090 mg/kg
12600 mg/kg
12600 mg/kg
12600 mg/kg
12600 mg/kg
100 mg/kg
-
Rat
10 mg/kg
-
Rat
5000 mg/kg
-
Rat
8 mL/kg
6/9
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Lysis/Binding/Wash Buffer
Lysis/Binding/Wash Buffer
11 . Toxicological information
Polyethyleneglycol-p-isooctylphenyl Ether
Conclusion/Summary
: Not available.
Chronic toxicity
Conclusion/Summary
: Not available.
Carcinogenicity
Conclusion/Summary
: Not available.
Classification
Product/ingredient name
ACGIH
glycerol
Polyethyleneglycol-p-isooctylphenyl
Ether
Mutagenicity
Conclusion/Summary
: Not available.
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Conclusion/Summary
13 . Disposal considerations
LD50 Oral
LD50 Oral
LD50 Oral
Rat
Rat
Rat
IARC
-
4190 mg/kg
3500 mg/kg
2800 mg/kg
EPA
-
NIOSH
None.
None.
-
NTP
-
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
14 . Transport information
OSHA
-
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
DOT Classification
Not
regulated.
-
-
-
IATA-DGR Class
Not
regulated.
-
-
-
PG* : Packing group
15 . Regulatory information
United States
HCS Classification
: Not available.
U.S. Federal regulations
: Not available.
Europe
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
:
:
:
:
:
:
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
12 . Ecological information
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
: No known significant effects or critical hazards.
Canada
WHMIS (Canada)
Canadian lists
: Not available.
13 . Disposal considerations
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Canada inventory
EU regulations
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: Canada inventory: Not determined.
International regulations
7/9
10/14/2008.
: Class D-2B: Material causing other toxic effects (Toxic).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: The following components are listed: Octylphenol and its ethoxylates
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: This product is not classified according to EU legislation.
:
Risk phrases
Hazardous waste
Biosciences Division
Pierce
: Irritating material
Target organ effects
: TSCA 8(a) PAIR: Polyethyleneglycol-p-isooctylphenyl Ether
United States inventory (TSCA 8b): All components are listed or exempted.
TSCA 8(d) H and S data reporting: glycerol
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Polyethyleneglycol-p-isooctylphenyl
Ether; glycerol
SARA 311/312 MSDS distribution - chemical inventory - hazard identification:
Polyethyleneglycol-p-isooctylphenyl Ether: Delayed (chronic) health hazard; glycerol:
Immediate (acute) health hazard, Delayed (chronic) health hazard
8/9
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Lysis/Binding/Wash Buffer
15 . Regulatory information
International lists
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): Not determined.
16 . Other information
Label requirements
Hazardous Material
Information System (U.S.A.)
: CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS
MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
:
Health
2
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
Flammability
0
Health
2
0
Instability
Special
Date of printing
: 10/14/2008.
: 10/14/2008.
Date of issue
Date of previous issue
: No previous validation.
Version
: 1
Indicates information that has changed from previously issued version.
Full text of R-phrases
: R36/37/38- Irritating to eyes, respiratory system and skin.
referred to in sections 2 and
3 - Europe
Full text of classifications
: Xi - Irritant
referred to in sections 2 and
3 - Europe
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
9/9
10/14/2008.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Anti-Ras Antibody
Material Safety Data Sheet
2.
Anti-Ras Antibody
1.
Product and company identification
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
: Anti-Ras Antibody
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
:
:
:
:
:
:
Manufacturer
3.
Composition/information on ingredients
Substance/preparation
: Substance
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
4.
First aid measures
Eye contact
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
Skin contact
Inhalation
2.
Hazards identification
Physical state
OSHA/HCS status
: Liquid.
: While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
Emergency overview
: NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin
and clothing.
Ingestion
Potential acute health effects
Inhalation
: No known significant effects or critical hazards.
Ingestion
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
Skin
: No known significant effects or critical hazards.
Eyes
Potential chronic health effects
Chronic effects
: No known significant effects or critical hazards.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Developmental effects
: No known significant effects or critical hazards.
Fertility effects
: No known significant effects or critical hazards.
Over-exposure signs/symptoms
Inhalation
: No specific data.
Ingestion
: No specific data.
Skin
: No specific data.
2/1/2008.
: No specific data.
: None known.
The substance is not classified as dangerous according to Directive 67/548/EEC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
89855D
4069
2/1/2008.
2/1/2008.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
Hazards identification
Eyes
Medical conditions
aggravated by overexposure
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention if irritation occurs.
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean
shoes thoroughly before reuse.
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. Get medical attention if symptoms occur. If unconscious, place in
recovery position and get medical attention immediately. Maintain an open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention if symptoms occur. Never give anything
by mouth to an unconscious person. If unconscious, place in recovery position and get
medical attention immediately. Maintain an open airway. Loosen tight clothing such as
a collar, tie, belt or waistband.
Protection of first-aiders
: No action shall be taken involving any personal risk or without suitable training.
See section 11 for more detailed information on health effects and symptoms.
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Hazardous combustion
products
Special protective
equipment for fire-fighters
1/6
2/1/2008.
: In a fire or if heated, a pressure increase will occur and the container may burst.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: No specific data.
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
2/6
Anti-Ras Antibody
6.
Anti-Ras Antibody
8.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Large spill
Small spill
7.
Handling and storage
Handling
Storage
8.
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist.
Keep in the original container or an approved alternative made from a compatible
material, kept tightly closed when not in use. Empty containers retain product residue
and can be hazardous. Do not reuse container.
: Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
Europe
No exposure limit value known.
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains ingredients
with exposure limits, use process enclosures, local exhaust ventilation or other
engineering controls to keep worker exposure below any recommended or statutory
limits.
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
2/1/2008.
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Hands
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Eyes
Skin
Environmental exposure
controls
9.
Physical and chemical properties
Physical state
Exposure controls/personal protection
Hygiene measures
Exposure controls/personal protection
Respiratory
3/6
: Liquid.
10 . Stability and reactivity
Stability
Conditions to avoid
Materials to avoid
Hazardous decomposition
products
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
11 . Toxicological information
United States
Acute toxicity
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
Carcinogenicity
Conclusion/Summary
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Europe
Conclusion/Summary
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
2/1/2008.
: Not available.
: Not available.
: Not available.
: Not available.
: Not available.
: Not available.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
4/6
Anti-Ras Antibody
Anti-Ras Antibody
11 . Toxicological information
Developmental effects
Fertility effects
15 . Regulatory information
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
Canada
WHMIS (Canada)
Canadian lists
12 . Ecological information
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
: No known significant effects or critical hazards.
Canada inventory
EU regulations
: Not available.
Risk phrases
13 . Disposal considerations
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
International regulations
International lists
Hazardous waste
Label requirements
Hazardous Material
Information System (U.S.A.)
UN number
Proper shipping
name
Classes
DOT Classification
Not available. Not available.
Not available.
-
IATA-DGR Class
Not available. Not available.
Not available.
-
PG*
15 . Regulatory information
United States inventory
(TSCA 8b)
2/1/2008.
: This product is not classified according to EU legislation.
:
: Australia inventory (AICS): Not determined.
China inventory (IECSC): Not determined.
Korea inventory (KECI): Not determined.
Philippines inventory (PICCS): Not determined.
Japan inventory (ENCS): Not determined.
: NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
:
Health
0
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
PG* : Packing group
United States
HCS Classification
U.S. Federal regulations
: Canada inventory: Not determined.
16 . Other information
14 . Transport information
Regulatory
information
: Not controlled under WHMIS (Canada).
: CEPA Toxic substances: This material is not listed.
Canadian ARET: This material is not listed.
Canadian NPRI: This material is not listed.
Alberta Designated Substances: This material is not listed.
Ontario Designated Substances: This material is not listed.
Quebec Designated Substances: This material is not listed.
Flammability
0
Health
: Not regulated.
: United States inventory (TSCA 8b): Not determined.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
0
0
Instability
Special
Date of printing
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
: United States inventory (TSCA 8b): Not determined.
5/6
: 2/1/2008.
: 2/1/2008.
Date of issue
Date of previous issue
: No previous validation.
Version
: 1
Indicates information that has changed from previously issued version.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
2/1/2008.
6/6
GST-Raf1-RBD
Material Safety Data Sheet
2.
GST-Raf1-RBD
1.
Product and company identification
Product name
Supplier
: GST-Raf1-RBD
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
Hazards identification
Target organs
Manufacturer
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
Ingestion
: No specific data.
Skin
: Adverse symptoms may include the following:
irritation
redness
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Eyes
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
2.
:
:
:
:
:
:
89855E
4070
2/1/2008.
2/1/2008.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
Medical conditions
aggravated by overexposure
Emergency overview
3.
: Liquid.
: Odorless.
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
: WARNING !
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS
MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
Irritating to eyes, respiratory system and skin. Avoid exposure - obtain special
instructions before use. Do not breathe vapor or mist. Avoid contact with eyes, skin and
clothing. Contains material that can cause target organ damage. Use only with
adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash
thoroughly after handling.
Potential acute health effects
Inhalation
:
:
Ingestion
:
Skin
:
Eyes
Potential chronic health effects
Chronic effects
:
Carcinogenicity
:
Mutagenicity
:
Teratogenicity
:
Developmental effects
:
Fertility effects
:
2/1/2008.
: Pre-existing disorders involving any target organs mentioned in this MSDS as being at
risk may be aggravated by over-exposure to this product.
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
Hazards identification
Physical state
Odor
OSHA/HCS status
: Contains material which causes damage to the following organs: kidneys, mucous
membranes, gastrointestinal tract, upper respiratory tract, skin, eye, lens or cornea.
Composition/information on ingredients
United States
Name
CAS number
56-81-5
GLYCEROL; GLYCERIN; GLYCERIN, ANHYDROUS; GLYCERIN, SYNTHETIC;
GLYCERINE; GLYCYL ALCOHOL; 1,2,3-PROPANETRIOL; SYNTHETIC GLYCERIN;
90 TECHNICAL GLYCERIN; TRIHYDROXYPROPANE; 1,2,3TRIHYDROXYPROPANE; GLYGERINE MIST
Europe
Substance/preparation
Ingredient name
%
10 - 20
: Preparation
CAS
number
56-81-5
Glycerol
%
EC number
10 - 20
200-289-5
Classification
[1] [2]
Xi;
R36/37/38
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
Occupational exposure limits, if available, are listed in section 8.
Irritating to respiratory system.
No known significant effects or critical hazards.
Irritating to skin.
Irritating to eyes.
4.
First aid measures
Eye contact
Contains material that can cause target organ damage.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
Skin contact
1/8
2/1/2008.
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention.
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Continue to rinse for at least 10 minutes. Get medical attention. Wash clothing
before reuse. Clean shoes thoroughly before reuse.
2/8
GST-Raf1-RBD
4.
GST-Raf1-RBD
First aid measures
Inhalation
Ingestion
Protection of first-aiders
6.
: Move exposed person to fresh air. If it is suspected that fumes are still present, the
rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep
person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest
occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous
to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention.
If unconscious, place in recovery position and get medical attention immediately.
Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention. Never give anything by mouth to an
unconscious person. If unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen tight clothing such as a collar,
tie, belt or waistband.
: No action shall be taken involving any personal risk or without suitable training. If it is
suspected that fumes are still present, the rescuer should wear an appropriate mask or
self-contained breathing apparatus. It may be dangerous to the person providing aid to
give mouth-to-mouth resuscitation.
See section 11 for more detailed information on health effects and symptoms.
5.
: In a fire or if heated, a pressure increase will occur and the container may burst.
Hazardous combustion
products
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: Decomposition products may include the following materials:
carbon oxides
Special protective
equipment for fire-fighters
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
6.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
8.
Exposure controls/personal protection
Europe
Glycerol
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Large spill
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
2/1/2008.
7.
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
Product name
United States
GLYCEROL; GLYCERIN; GLYCERIN,
ANHYDROUS; GLYCERIN, SYNTHETIC;
GLYCERINE; GLYCYL ALCOHOL; 1,2,3PROPANETRIOL; SYNTHETIC GLYCERIN; 90
TECHNICAL GLYCERIN;
TRIHYDROXYPROPANE; 1,2,3TRIHYDROXYPROPANE; GLYGERINE MIST
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Accidental release measures
Small spill
3/8
Exposure limits
ACGIH (United States, 0/2000).
TWA: 10 mg/m³
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
OSHA PEL (United States).
TWA: 15 mg/m³ 8 hour(s). Form: Total dust
OSHA (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³
TWA: 5 mg/m³
ACGIH TLV (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
OSHA PEL 1989 (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
ACGIH (United States, 0/2000).
TWA: 10 mg/m³
ACGIH TLV (United States).
TWA: 10 mg/m³ 8 hour(s). Form: Total particulates
ACGIH TLV (United States, 0/1989). Notes: Respirable
TWA: 5 mg/m³ 8 hour(s).
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
2/1/2008.
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor
or mist, use process enclosures, local exhaust ventilation or other engineering controls
to keep worker exposure to airborne contaminants below any recommended or statutory
limits.
4/8
GST-Raf1-RBD
8.
GST-Raf1-RBD
Exposure controls/personal protection
Hygiene measures
Personal protection
Respiratory
11 . Toxicological information
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Hands
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
Eyes
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Environmental exposure
controls
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
9.
Physical and chemical properties
Physical state
Color
Odor
pH
Dispersibility properties
Solubility
:
:
:
:
:
:
Conditions to avoid
Materials to avoid
Hazardous decomposition
products
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
2/1/2008.
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Europe
Conclusion/Summary
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
: Not available.
ACGIH
-
IARC
-
EPA
-
NIOSH
None.
NTP
-
OSHA
-
: Not available.
: Not available.
: Not available.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
12 . Ecological information
Conclusion/Summary
: No known significant effects or critical hazards.
: Not available.
13 . Disposal considerations
Waste disposal
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
11 . Toxicological information
United States
Acute toxicity
Product/ingredient name
Glycerol
Conclusion/Summary
Classification
Product/ingredient name
Glycerol
Environmental effects
United States
Aquatic ecotoxicity
Liquid.
Colorless.
Odorless.
7.2
Partially dispersible in the following materials: cold water.
Soluble in the following materials: cold water.
10 . Stability and reactivity
Stability
Carcinogenicity
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Hazardous waste
14 . Transport information
Result
LD50 Oral
LD50 Oral
LD50 Oral
: Not available.
Species
Rat
Guinea pig
Mouse
Dose
12600 mg/kg
7750 mg/kg
4090 mg/kg
Exposure
-
: Not available.
Regulatory
information
UN number
DOT Classification
IATA-DGR Class
Proper shipping
name
Classes
PG*
Not available. Not available.
Not available.
-
Not available. Not available.
Not available.
-
PG* : Packing group
5/8
2/1/2008.
6/8
GST-Raf1-RBD
GST-Raf1-RBD
15 . Regulatory information
16 . Other information
United States
HCS Classification
National Fire Protection
Association (U.S.A.)
U.S. Federal regulations
: Irritating material
Target organ effects
: TSCA 8(a) PAIR: Triton
United States inventory (TSCA 8b): Not determined.
TSCA 8(d) H and S data reporting:
Canada inventory
EU regulations
Risk phrases
International regulations
International lists
Flammability
0
Health
2
0
Instability
Special
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals:
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: :
Immediate (acute) health hazard, Delayed (chronic) health hazard
United States inventory
(TSCA 8b)
Canada
WHMIS (Canada)
Canadian lists
:
: 2/1/2008.
: 2/1/2008.
Date of issue
: No previous validation.
Date of previous issue
: 1
Version
Indicates information that has changed from previously issued version.
: R36/37/38- Irritating to eyes, respiratory system and skin.
Full text of R-phrases
referred to in sections 2 and
3 - Europe
: Xi - Irritant
Full text of classifications
referred to in sections 2 and
3 - Europe
Date of printing
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
: United States inventory (TSCA 8b): Not determined.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
: Not controlled under WHMIS (Canada).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: Canada inventory: Not determined.
: This product is not classified according to EU legislation.
:
: Australia inventory (AICS): Not determined.
China inventory (IECSC): Not determined.
Korea inventory (KECI): Not determined.
Philippines inventory (PICCS): Not determined.
Japan inventory (ENCS): Not determined.
16 . Other information
Label requirements
Hazardous Material
Information System (U.S.A.)
: CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS
MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
:
Health
2
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
2/1/2008.
7/8
2/1/2008.
8/8
GDP (100mM)
Material Safety Data Sheet
2.
GDP (100mM)
1.
Product and company identification
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
2.
: GDP (100mM)
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
:
:
:
:
:
:
Manufacturer
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
3.
Composition/information on ingredients
Substance/preparation
: Preparation
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
4.
First aid measures
Eye contact
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
Skin contact
Inhalation
Hazards identification
Physical state
Odor
OSHA/HCS status
: Liquid.
: Odorless.
: While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
Emergency overview
: NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin
and clothing.
Ingestion
Potential acute health effects
Inhalation
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
Ingestion
: No known significant effects or critical hazards.
Skin
: No known significant effects or critical hazards.
Eyes
Potential chronic health effects
Chronic effects
: No known significant effects or critical hazards.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Developmental effects
: No known significant effects or critical hazards.
Fertility effects
: No known significant effects or critical hazards.
Over-exposure signs/symptoms
Inhalation
: No specific data.
Ingestion
: No specific data.
2/1/2008.
: No specific data.
: No specific data.
: None known.
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
89855F
4071
2/1/2008.
2/1/2008.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
Hazards identification
Skin
Eyes
Medical conditions
aggravated by overexposure
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention if irritation occurs.
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean
shoes thoroughly before reuse.
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. Get medical attention if symptoms occur. If unconscious, place in
recovery position and get medical attention immediately. Maintain an open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention if symptoms occur. Never give anything
by mouth to an unconscious person. If unconscious, place in recovery position and get
medical attention immediately. Maintain an open airway. Loosen tight clothing such as
a collar, tie, belt or waistband.
Protection of first-aiders
: No action shall be taken involving any personal risk or without suitable training.
See section 11 for more detailed information on health effects and symptoms.
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Hazardous combustion
products
Special protective
equipment for fire-fighters
1/7
2/1/2008.
: In a fire or if heated, a pressure increase will occur and the container may burst.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: No specific data.
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
2/7
GDP (100mM)
6.
GDP (100mM)
8.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Large spill
Small spill
7.
Handling and storage
Handling
Storage
8.
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist.
Keep in the original container or an approved alternative made from a compatible
material, kept tightly closed when not in use. Empty containers retain product residue
and can be hazardous. Do not reuse container.
: Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
Exposure controls/personal protection
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains ingredients
with exposure limits, use process enclosures, local exhaust ventilation or other
engineering controls to keep worker exposure below any recommended or statutory
limits.
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
2/1/2008.
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Hands
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Eyes
Skin
Environmental exposure
controls
9.
Physical and chemical properties
Physical state
Color
Odor
Solubility
:
:
:
:
Liquid.
Colorless.
Odorless.
Soluble in the following materials: cold water.
10 . Stability and reactivity
Stability
Conditions to avoid
Materials to avoid
Hazardous decomposition
products
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
11 . Toxicological information
Europe
No exposure limit value known.
Hygiene measures
Exposure controls/personal protection
Respiratory
3/7
United States
Acute toxicity
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
Carcinogenicity
Conclusion/Summary
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Europe
Conclusion/Summary
Chronic effects
2/1/2008.
: Not available.
: Not available.
: Not available.
: Not available.
: Not available.
: Not available.
: No known significant effects or critical hazards.
4/7
GDP (100mM)
GDP (100mM)
11 . Toxicological information
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
:
:
:
:
:
15 . Regulatory information
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
United States inventory
(TSCA 8b)
Canada
WHMIS (Canada)
Canadian lists
12 . Ecological information
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
: No known significant effects or critical hazards.
Canada inventory
EU regulations
: Not available.
Risk phrases
13 . Disposal considerations
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
International regulations
International lists
Hazardous waste
UN number
Proper shipping
name
Classes
DOT Classification
Not available. Not available.
Not available.
-
IATA-DGR Class
Not available. Not available.
Not available.
-
: Not controlled under WHMIS (Canada).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: Canada inventory: Not determined.
: This product is not classified according to EU legislation.
:
: Australia inventory (AICS): Not determined.
China inventory (IECSC): Not determined.
Korea inventory (KECI): Not determined.
Philippines inventory (PICCS): Not determined.
Japan inventory (ENCS): Not determined.
16 . Other information
14 . Transport information
Regulatory
information
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
: United States inventory (TSCA 8b): Not determined.
Label requirements
: NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
Hazardous Material
Information System (U.S.A.)
:
PG*
Health
0
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
National Fire Protection
:
Association (U.S.A.)
PG* : Packing group
15 . Regulatory information
United States
HCS Classification
U.S. Federal regulations
: Not regulated.
: United States inventory (TSCA 8b): Not determined.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
0
0
Instability
Special
Date of printing
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
2/1/2008.
Flammability
0
Health
5/7
: 2/1/2008.
: 2/1/2008.
Date of issue
Date of previous issue
: No previous validation.
Version
: 1
Indicates information that has changed from previously issued version.
Notice to reader
2/1/2008.
6/7
GDP (100mM)
Material Safety Data Sheet
16 . Other information
GTP-gamma-S (10 mM)
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
1.
Product and company identification
Product name
Supplier
: GTP-gamma-S (10 mM)
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
:
:
:
:
:
:
2.
Manufacturer
: ThermoFisher Scientific
(Milwaukee) LLC
2202 N. Bartlett Ave.
Milwaukee, WI 53202
USA
414.227.3600 or
877.886.7629
89855G
4072
2/1/2008.
2/1/2008.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
Hazards identification
Physical state
Odor
OSHA/HCS status
: Liquid.
: Odorless.
: While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
Emergency overview
: NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin
and clothing.
Potential acute health effects
Inhalation
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
Ingestion
: No known significant effects or critical hazards.
Skin
: No known significant effects or critical hazards.
Eyes
Potential chronic health effects
Chronic effects
: No known significant effects or critical hazards.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Developmental effects
: No known significant effects or critical hazards.
Fertility effects
: No known significant effects or critical hazards.
Over-exposure signs/symptoms
Inhalation
: No specific data.
Ingestion
: No specific data.
2/1/2008.
7/7
2/1/2008.
1/7
GTP-gamma-S (10 mM)
2.
GTP-gamma-S (10 mM)
Hazards identification
Skin
Eyes
Medical conditions
aggravated by overexposure
6.
: No specific data.
: No specific data.
: None known.
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
3.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Large spill
Composition/information on ingredients
Substance/preparation
: Preparation
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
4.
Small spill
First aid measures
Eye contact
Skin contact
Inhalation
Ingestion
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention if irritation occurs.
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean
shoes thoroughly before reuse.
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. Get medical attention if symptoms occur. If unconscious, place in
recovery position and get medical attention immediately. Maintain an open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention if symptoms occur. Never give anything
by mouth to an unconscious person. If unconscious, place in recovery position and get
medical attention immediately. Maintain an open airway. Loosen tight clothing such as
a collar, tie, belt or waistband.
Protection of first-aiders
: No action shall be taken involving any personal risk or without suitable training.
See section 11 for more detailed information on health effects and symptoms.
5.
Hazardous combustion
products
Special protective
equipment for fire-fighters
2/1/2008.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist.
Keep in the original container or an approved alternative made from a compatible
material, kept tightly closed when not in use. Empty containers retain product residue
and can be hazardous. Do not reuse container.
Storage
: Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
8.
Exposure controls/personal protection
Europe
No exposure limit value known.
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains ingredients
with exposure limits, use process enclosures, local exhaust ventilation or other
engineering controls to keep worker exposure below any recommended or statutory
limits.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
7.
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
: In a fire or if heated, a pressure increase will occur and the container may burst.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: No specific data.
Hygiene measures
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
2/7
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
2/1/2008.
3/7
GTP-gamma-S (10 mM)
8.
GTP-gamma-S (10 mM)
Exposure controls/personal protection
11 . Toxicological information
Respiratory
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Hands
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Eyes
Skin
Environmental exposure
controls
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
:
:
:
:
Liquid.
Colorless.
Odorless.
Soluble in the following materials: cold water.
Conditions to avoid
Materials to avoid
Hazardous decomposition
products
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
11 . Toxicological information
United States
Acute toxicity
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
Carcinogenicity
Conclusion/Summary
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Europe
Conclusion/Summary
Chronic effects
2/1/2008.
: Not available.
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Hazardous waste
10 . Stability and reactivity
Stability
: No known significant effects or critical hazards.
13 . Disposal considerations
Physical and chemical properties
Physical state
Color
Odor
Solubility
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
12 . Ecological information
Waste disposal
9.
:
:
:
:
:
14 . Transport information
Regulatory
information
UN number
DOT Classification
IATA-DGR Class
Proper shipping
name
Classes
PG*
Not available. Not available.
Not available.
-
Not available. Not available.
Not available.
-
PG* : Packing group
15 . Regulatory information
: Not available.
United States
HCS Classification
U.S. Federal regulations
: Not available.
: Not available.
: Not available.
: Not available.
: Not regulated.
: United States inventory (TSCA 8b): Not determined.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
: Not available.
: No known significant effects or critical hazards.
4/7
2/1/2008.
5/7
GTP-gamma-S (10 mM)
GTP-gamma-S (10 mM)
15 . Regulatory information
United States inventory
(TSCA 8b)
Canada
WHMIS (Canada)
Canadian lists
Canada inventory
EU regulations
Risk phrases
International regulations
International lists
16 . Other information
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
: United States inventory (TSCA 8b): Not determined.
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
: Not controlled under WHMIS (Canada).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: Canada inventory: Not determined.
: This product is not classified according to EU legislation.
:
: Australia inventory (AICS): Not determined.
China inventory (IECSC): Not determined.
Korea inventory (KECI): Not determined.
Philippines inventory (PICCS): Not determined.
Japan inventory (ENCS): Not determined.
16 . Other information
Label requirements
: NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
Hazardous Material
Information System (U.S.A.)
:
Health
0
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
National Fire Protection
:
Association (U.S.A.)
Flammability
0
Health
0
0
Instability
Special
Date of printing
: 2/1/2008.
: 2/1/2008.
Date of issue
Date of previous issue
: No previous validation.
Version
: 1
Indicates information that has changed from previously issued version.
Notice to reader
2/1/2008.
6/7
2/1/2008.
7/7