BV Fast and Accurate Detection of Bacterial Vaginosis Clinical Relevance u u u u u BV is caused by an imbalance of naturally occurring bacterial flora. BV is not classified as an STD but may be related to sexual activity.1 Typical diagnostic criteria include discharge, odour, pH evaluation and microscope examination microorganisms The most common treatment is antibiotic therapy. Diagnosis of BV by genetic testing is equally sensitive but more rapid than conventional methods.3 Clinical Utility u An estimated 33% of women will contract BV at some time during their lives.2 u Studies show that subclinical iron deficiency is a strong predictor of bacterial vaginosis in pregnant women.4 u A longitudinal study showed a link between psychosocial stress and bacterial vaginosis independent of other risk factors.5 Microorganisms Tested B. fragilis Mob. mulleris Ato vaginae G. vaginalis Mob. curtis Pre. biviae Sample Type and Volume u u Whole blood, saliva or buccal swabs (Natural Molecular Buccal Swab Kits Preferred) Vaginal swab References 1. http://www.stdservices.on.net/std/bacterial_vaginosis/facts.htm 2. http://www.nationaljewish.org/healthinfo/conditions/ntm/diagnosis.aspx 3. Gazi H, Degerli K, Kurt O, et al. (2006). “Use of DNA hybridization test for diagnosing bacterial vaginosis in women with symptoms suggestive of infection”. APMIS 114 (11): 784–7. doi:10.1111/j.1600-0463.2006. apm_485.x. PMID 17078859 4. Verstraelen, H; Delanghe, J; Roelens, K; Blot,S; Clauys, G and Temmermann, M (2005): Subclinical iron deficiency is a strong predictor of bacterial vaginosis in early pregnancy.BMC Infect Dis. 2005; 5: 55. 5. Nansel,TR; Riggs, MA; YU, KF and Andrews, WW: The association of psykhosocial stress and bacterial vaginosis in a longitudinal cohort Am.J Obst. Gynecol. 194, (2), p 381-386. 888-442-8881 x 11 [email protected] naturalmolecular.com
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