Xiongzhi (Chee) Chen Lewis-Sigler Institute for Integrative Genomics Carl Icahn Laboratory Princeton University Princeton, NJ 08544 Phone: 1-765-413-7825 Fax: 1-609-258-8020 E-mail: [email protected] http://www.princeton.edu/~xiongzhi Personal Information Citizenship: People’s Republic of China Visa status: H-1B Marital status: Married with two children Languages: Chinese (native), English (fluent) Education Ph.D. in Statistics, Aug 2009 - Dec 2012 Purdue University, West Lafayette, Indiana, USA Advisor: Rebecca W. Doerge Dissertation: General Methods for Adaptive Control and Estimation of False Discovery Rate M.A. in Mathematics, Aug 2007 - May 2009 University of Hawaii, Honolulu, Hawaii, USA Advisor: L. Thomas Ramsey Thesis: The Shanghai Stock Exchange: Statistical Properties and Simulation by Hyperbolic Diffusion M.S. in Mathematics, Sept 2003 - June 2006 Sichuan University, Chengdu, Sichuan, China Advisor: Changlin Cai Thesis: Infinite Dimensional Statistical Neural Manifold Research Interests 1. 2. 3. 4. 5. Large-scale statistical inference for dependent data and discrete data Variable and model selection via regularization Scalability of Markov chain Monte Carlo methods for high-dimensional statistics Stochastic differential equations and their applications to mathematical finance Spectral theory of random matrices and its applications to multivariate statistics Publications and Submitted Manuscripts Xiongzhi Chen and R.W. Doerge (2012): Generalized estimators for multiple testing: proportion of true nulls and false discovery rate. Submitted to “Journal of the Royal Statistical Society, Series B”; available at http: // arxiv. org/ abs/ 1410. 4274 . Xiongzhi Chen and R.W. Doerge (2012): Estimating the proportion of nonzero normal means under certain strong covariance dependence. Submitted to “Journal of the American Statistical Association”; available at http: // arxiv. org/ abs/ 1410. 4275 . Xiongzhi Chen and R.W. Doerge (2012): On a strong law of larger numbers related to multiple testing normal means. Submitted to “The Annals of Statistics”; available at http: // arxiv. org/ abs/ 1410. 4276 . Xiongzhi Chen and R.W. Doerge (2012): Towards better FDR procedures for discrete test statistics. Proceedings of Kansas State University Conference on Applied Statistics in Agriculture, 294-303. Xiongzhi Chen and Changlin Cai (2006): A new architecture for multilayer perceptrons as function approximators. Natural Science Edition, Journal of Sichuan University, Vol. 2. Xiongzhi (Chee) Chen, Princeton University, CV Oct. 2014, 1 of 3 Changlin Cai, Zhongzhi Shi, Xiongzhi Chen (2006). The Fisher information matrix on neural manifolds of multilayer perceptrons. Natural Science Edition, Journal of Sichuan University, Accepted. Manuscripts and Work In Progress Xiongzhi Chen and John D. Storey (2014): Nonparametric estimation of row space of dependence kernel and nonparametric CDI algorithm. Manuscript. Xiongzhi Chen and John D. Storey (2014): Estimating the proportion of true nulls via goodness of fit. Manuscript. John D. Storey and Xiongzhi Chen (2014): Recovering linear latent structure in high-dimensional data. Manuscript. David G. Robinson, Xiongzhi Chen and John D. Storey (2014): Functional false discovery rate control for multiple hypothesis testing in genomics. Manuscript. Keyur H. Desai, John D. Storey and Xiongzhi Chen (2013): Empirical Bayes inference of dependent highdimensional data. Manuscript. Xiongzhi Chen and R.W. Doerge (2013): False discovery rate control under discrete and heterogeneous null p-value distributions. Manuscript. Xiongzhi Chen and John D. Storey (2014): One parameter natural exponential families with reducible variance functions. In preparation. Xiongzhi Chen and John D. Storey (2014): Approximate high dimensional Markov Chains. In preparation. Xiongzhi Chen and John D. Storey (2014): On the singularity probability of random Bernoulli matrices. In preparation. Presentations and Posters Xiongzhi Chen (Nov 2012): Classification of objects and false discovery rate. Poster: The 3rd Purdue University Annual Next Generation Scholars Research Fair. Xiongzhi Chen (Oct 2012): General methods for adaptive control and estimation of false discovery rate. Presentation: Purdue Statistics Graduate Student Seminar. Xiongzhi Chen (May 2012): A generalized estimator of the proportion of true nulls for multiple testing. Presentation: Kansas State University Conference on Applied Statistics in Agriculture, Kansas State University, Manhattan, KS. Xiongzhi Chen and R.W. Doerge (May 2011): Dependent test statistics and control of false discovery rate. Poster: Kansas State University Conference on Applied Statistics in Agriculture, Kansas State University, Manhattan, KS. Research and Consulting Experience Postdoctoral Research Associate for John D. Storey: Princeton University, Lewis-Sigler Institute Dates: May 2013 - Present Responsibilities: Developing theory and methodologies for high-dimensional statistical inference under dependence. Postdoctoral Research Assistant for Rebecca W. Doerge: Purdue University, Department of Statistics Dates: Jan 2013 - Apr 2013 Responsibilities: Developing statistical theory and methodologies for multiple testing with discrete genomic data. Research Assistant for Rebecca W. Doerge: Purdue University, Department of Statistics Xiongzhi (Chee) Chen, Princeton University, CV Oct. 2014, 2 of 3 Dates: June 2012 - Dec 2012 Responsibilities: Developing non-permutation based multiple testing methods for highdimensional dependent data and discrete data. Research Assistant for Rebecca W. Doerge: Purdue University, Department of Statistics Dates: Jan 2012 - May 2012 Responsibilities: Processing and integrated statistical analysis of SNP, mRNA and miRNA data generated from various platforms. Consultant: Statistical Consulting Service (SCS), Purdue University, Department of Statistics Dates: Aug 2010 - Dec 2011 Responsibilities: Assisting members of Purdue’s academic community with statistical design, data analysis, and software issues for their research. Research Assistant for Dabao Zhang: Purdue University, Department of Statistics Dates: Jan 2010 - Aug 2010 Responsibilities: Contributing to methodologies in estimating distribution of extreme values; assisting the development of generalized cross validation for penalized orthogonal-components regression. Teaching Experience Teaching Assistant: Purdue University, Department of Statistics Dates: Aug 2009 - Dec 2009 Courses: Elementary Statistical Methods (STAT 301), Statistics and Society (STAT 113). Responsibilities: Co-leading lab sessions where students used SPSS to practice statistical methods covered in lecture; teaching recitation sessions; writing and grading quizzes, home-work, and exams. Adjunct Teacher: Transpacific Hawaii Collage Dates: July 2008 - Sept 2008 Course: Elementary Statistics (MATH 200). Responsibilities: Teaching the course; writing and grading homework, quizzes and exams. Teaching Assistant: University of Hawaii, Department of Mathematics Dates: Aug 2007 - May 2009 Courses: Applied Calculus (MATH 215, MATH 216). Responsibilities: Leading lab sessions where students used Derive to practice techniques of calculus covered in lecture; teaching recitation sessions; grading homework, quizzes and exams. Scholarships/Fellowships/Awards Graduate Assistantship, Department of Statistics, Purdue University Dates: Aug 2009 - Dec 2012 Graduate Assistantship, Department of Mathematics, University of Hawaii Dates: Aug 2007 - May 2009 Computing and Computer Skills Softwares: R, SAS, SPSS, Matlab, Mathematica, Perl, LATEX Operating Systems: Windows and Linux Professional Organizations Society for Industrial and Applied Mathematics (SIAM) American Statistical Association (ASA) Xiongzhi (Chee) Chen, Princeton University, CV Oct. 2014, 3 of 3