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Last Update: October 16, 2014
Jaepyeong Cha
402 Barton Hall, Johns Hopkins University
3400 N. Charles Street, Baltimore, MD 21218
[email protected]
(410) 516-4068
RESEARCH INTERESTS
Functional Brain Imaging in Living Animals
• Spatially multiplexed fiber-optic microscopy for simultaneous imaging of multiple regions
• Real-time in vivo fiber-optic deep brain imaging in freely behaving animals
• Optical stimulation and control of optogenetic cells (Spatio-temporal control of brain activity)
Medical Imaging guided Surgical Intervention
• Fiber optic guided multispectral imaging for smart tissue anastomosis robot (STAR)
• Real-time OCT (Optical Coherence Tomography) guided microsurgery
• High speed image acquisition and GPU based real-time processing
EDUCATION
Johns Hopkins University, Electrical and Computer Engineering
Baltimore, Maryland
PhD Candidate
2011 – Aug, 2016
Seoul National University, Biomedical Engineering
2009 – 2011
Seoul, Korea
Master of Science
M.S. thesis: “A Study on the method of Optical Energy Harvesting for Implantable Medical Devices“
Seoul National University, Electrical and Computer Engineering
Seoul, Korea
Bachelor of Science
Senior project: “Development of Portable Fundus Camera system “
2002 – 2007
ACADEMIC EXPERIENCE
Johns Hopkins University, Electrical and Computer Engineering
September 2011 – Present
Teaching (Class) Assistant
• Assisted in the following lecture class (including teaching and assignment grading); Spring 2013
– Biophotonics Laboratory (Prof. Jin U. Kang), Fall 2013 – Advanced ECE Engineering Team
Projects (Prof. Jin U. Kang)
Graduate Research Assistant
Project title: “Development of Ultralight Biophotonic Neuro-cellular Imaging Platform for
Elucidating Brain Activity in Freely-behaving Animals”, 10/01/2014-12/31/2016
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Advisor: Dr. Jin U. Kang (Department of Electrical and Computer Engineering, Johns Hopkins
University)
Collaboration with Dr. Xingde Li (Department of Biomedical Engineering, Johns Hopkins
School of Medicine) and Dr. Dwight E. Bergles (The Solomon H. Snyder Department of
Neuroscience, Johns Hopkins School of Medicine)
Activity: Develop an ultracompact, portable and head-mountable imaging platform, which will
enable imaging of brain activity with subcellular resolution in freely behaving animals.
Funded by “NSF-MRI” (1430040, Major Research Instrumentation)
Project title: “The role of astrocytes in reward-based learning”, 06/01/2013-05/31/2015
• Advisor: Dr. Jin U. Kang (Department of Electrical and Computer Engineering, Johns Hopkins
University)
• Collaboration with Dr. Dwight E. Bergles and Dr. Marshall G. Hussain Shuler (The Solomon H.
Snyder Department of Neuroscience, Johns Hopkins School of Medicine)
• Activity: Optimization of the optical fiber imaging system and adapting this imaging platform
for use in freely moving mice
• Funded by “Science of Learning Institute in Johns Hopkins University”
Project title: “Multispectral tissue analysis for optimizing anastomosis placements”, 06/01/201305/30/2014
• Advisor: Dr. Jin U. Kang (Department of Electrical and Computer Engineering, Johns Hopkins
University)
• Collaboration with Dr. Peter Kim, Dr. Axel Krieger, and Dr. Azad Shademan (The Sheikh Zayed
Institute for Pediatric Surgical Innovation Team, Children’s National Hospital)
• Activity: Development of multispectral imaging system and multispectral image analysis
• Funded by “Sheikh Zayed Institute for Surgical Innovation, Children’s National Medical Center.”
Project title: “Neuroimaging Project”, 01/01/2013-06/30/2013
• Advisor: Dr. Jin U. Kang (Department of Electrical and Computer Engineering, Johns Hopkins
University)
• Collaboration with Dr. Dwight E. Bergles and Dr. Martin Paukert (Department of Neuroscience,
School of Medicine, Johns Hopkins University)
• Activity: Development of all fiber-optic real-time neuroimaging system
• Funded by “The Johns Hopkins Brain Science Institute (BSi).”
Project title: “Fluorescent sensors for neurotransmitters –towards real-time imaging of
acetylcholine in vivo”, 08/31/2011-12/31/2012
• Advisor: Dr. Jin U. Kang (Department of Electrical and Computer Engineering, Johns Hopkins
University)
• Collaboration with Dr. Min Li and Dr. Marshall H. Shuler (The Solomon H. Snyder department
of Neuroscience, Johns Hopkins School of Medicine)
• Activity: Development of all fiber-optic real-time fluorescence imaging system
• Funded by “The Johns Hopkins Brain Science Institute (BSi).”
Seoul National University, Biomedical Engineering
Teaching (Class) Assistant
September 2009 – August 2011
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Assisted in the following lecture classes (including teaching and assignment grading); Spring
2011 – Biomedical Signal Analysis (Prof. Sungwan Kim), Fall 2010 – Introduction to
Bioengineering І (Prof. Hee Chan Kim), Spring 2010 – Bioengineering Seminar І (Prof. Hee
Chan Kim), Fall 2009 – Introduction to Biomedical Engineering (Prof. Hee Chan Kim)
Graduate Research Assistant
Project title: “Development of multi-functional U-healthcare system for Chronological Obstructive
Pulmonary Disease (COPD) patient”
• Advisor: Dr. Hee Chan Kim (Department of Biomedical Engineering, School of Medicine, Seoul
National University Hospital, Seoul, Korea)
• Activity: Optimization of the developed system and evaluation with more than 200 subjects
• Funded by “National Ministry of Health and Welfare (A085034), Korea.”
Seoul National University, Electrical and Computer Engineering November 2005 – February 2007
Undergraduate Research Intern at Medical Electronics Laboratory
• Senior Project title: “Development of Portable Fundus Camera system”
• Advisor: Dr. Hee Chan Kim (Department of Biomedical Engineering, School of Medicine, Seoul
National University Hospital)
• Collaboration with Dr. Jong Mo Seo (Division of Ophthalmology, Seoul National University
Hospital)
• Activity: Development a cost-effective portable stereo retina imaging system for the optic
disease
PROFESSIONAL / LEADERSHIP EXPERIENCE
Optical Society of America (OSA) Baltimore Student Chapter
President
June 2014 – Present
• To run meetings in an orderly fashion, to make necessary decisions, and to represent and be
responsible for the chapter’s activities.
Vice president
May 2013 – May 2014
• To assist the President and to serve in his/her absence. To assist with the execution of chapter
activities.
Johns Hopkins University Korean Graduate Student Association
November 2011 – March 2013
Vice President
• Representative of a nonprofit organization to provide services to the Korean graduate students
community in Hopkins (including Homewood campus, School of medicine, School of nursing,
Peabody Institute, Bloomberg school of public health, SAIS, Carey school of Business)
• Activity: Events organization, website management, mentoring for undergraduate and new
students, Job opportunity posting, etc.
5th Infantry Division of Korean Army, Logistics Battalion
March 2007 – June 2009
Lieutenant (Platoon leader)
• Advised by Captain Chun Soo Lee, Colonel Sung Kyun Park, and General Hyuk Soon Kwon
• Served Reserved Officers’ Training Corps (R.O.T.C) at Seoul National University
• Activity: Platoon management (discipline soldiers and enhance morale and combat readiness)
Ministry of National Defense, Office of Personnel and Welfare November 2007 – November 2008
Examiner and proctor
• Nominated by Minister of National Defense of Korea
• Activity: Setting exam questions for civilian workers in the military (new employee, promotion)
SCHOLARLY ACTIVITIES
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SPIE Journal of Medical Imaging, Reviewer
IEEE Student Member, Member
OSA Student Member, Member
SPIE Student Member, Member
OSA Optics Letters, Reviewer
SPIE Journal of Biomedical Optics, Reviewer
IEEE Journal of Selected Topics in Quantum Electronics, Reviewer
SPIE Technical Group: TG Laser Communication , Member
2014 – Present
2014 – Present
2013 – Present
2013 – Present
2013 – Present
2012 – Present
2011 – Present
2007 – 2008
AWARDS/HONORS
Howard Hughes Medical Institute (HHMI) International Student Research Fellowship
KSEA-KUSCO Scholarship
KASF-ERC Scholarship Award, Korean American Scholarship Foundation
Graduate Doctoral Fellowship, Johns Hopkins University
BK21 Scholarship, Ministry of Education & Human Resources Development, Korea
Commendation for great services, Logistics Battalion, Korean Army, Korea
Top Academic Undergraduate Paper Awards, Seoul National University, Korea
First prize at Electronics Fair, Seoul National University, Korea
2014 – 2016
2014
2013
2011 – 2014
2010, 2011
2008, 2009
2007
2006
PEER-REVIEWED JOURNAL PUBLICATIONS
[J-6] Gyeong Woo Cheon, Yong Huang, Jaepyeong Cha, Peter L. Gehlbach, and Jin U. Kang, “Active
depth targeting and locking for retinal microsurgery based on robust CP-SSOCT distal sensing,” Optics
Express (Submitted).
[J-5] Gyeong Woo Cheon, Jaepyeong Cha, and Jin U. Kang, “Random transverse motion-induced
spatial compounding for fiber bundle imaging,” Optics Letters 39(15), 4368-4371 (2014). [Link]
“Selected by the Editors, Andrew Dunn and Anthony Durkin, for publication in the issue of the
Virtual Journal for Biomedical Optics (VJBO), which is a special feature of OSA's Optics
InfoBase, http://vjbo.osa.org/virtual_issue.cfm.”
[J-4] Martin Paukert, Amit Agarwal, Jaepyeong Cha, Van A. Doze, Jin U. Kang, and Dwight E.
Bergles, “Norepinephrine controls astroglial responsiveness to local circuit activity,” Neuron 82(6),
1263-1270 (2014). [Link]
[J-3] Chang Kyu Yoon, Rui Xiao, Jae Hyun Park, Jaepyeong Cha, Thao D. Nguyen, and David H.
Gracias, “Functional stimuli responsive hydrogel devices by self-folding,” Smart Materials and
Structures 23 094008 (2014). [Link]
[J-2] Jaepyeong Cha, Jing Zhang, Saumya Gurbani, Gyeong Woo Cheon, Min Li, and Jin U. Kang,
“Gene transfection efficacy assessment of human cervical cancer cell using dual-mode fluorescence
microendoscopy,” Biomedical Optics Express 4(1), 151-159 (2013). [Link]
[J-1] J. Kang, Y. Huang, K. Zhang, Z. Ibrahim, J. Cha, W. Lee, G. Brandacher, and P. Gehlbach, "Realtime three-dimensional Fourier-domain optical coherence tomography video image guided
microsurgeries," Journal of Biomedical Optics 17, 081403 (2012). [Link]
CONFERENCE PUBLICATIONS AND PRESENTATIONS
[C-17] Jaepyeong Cha, Gyeong Woo Cheon, and Jin U. Kang “Automated long-term tracking of freely
moving animal and functional brain imaging based on fiber-optic microscopy,” SPIE Photonics West
2015, February 7, San Francisco, USA, 2015. (Accepted for Oral Presentation)
[C-16] Jaepyeong Cha, “Fiber-optic techniques towards brain imaging in freely moving animals,”
Johns Hopkins OSA Student Chapter General Body Meeting, September 29, Baltimore, USA, 2014.
(Invited Talk)
[C-15] Il-hyung Shin, Jaepyeong Cha, Gyeong Woo Cheon, Choonghee Lee, Seung Yup Lee, HyungJin Yoon and Hee Chan Kim, “Automatic stress-relieving music recommendation system based on
photoplethesmography-derived heart rate variability analysis,” Proceedings of the 36th International
Conference of the IEEE Engineering in Medicine and Biology Society, August 26-30, Chicago, USA,
2014. (Lecture presentation &Peer-reviewed conference publication).
[C-14] J. Cha and J. U. Kang, "Spatially Multiplexed Fiber-optic Microscopy for Simultaneous Imaging
of Multiple Brain Regions," in CLEO: 2014, OSA Technical Digest (online) (Optical Society of
America, 2014), paper AF1B.3. (Oral presentation & Peer-reviewed conference publication) [Link]
[C-13] Jaepyeong Cha, Brian Triana, Azad Shademan, Axel Krieger, Peter C. W. Kim, and Jin U. Kang,
“Polarization-sensitive multispectral imaging for optimizing intestinal anastomosis placements,” Proc.
SPIE 9036, Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling,
90360H (March 12, 2014); doi:10.1117/12.2043693. (Oral presentation & Peer-reviewed conference
publication) [Link]
[C-12] Gyeong Woo Cheon, Jaepyeong Cha, and Jin U. Kang, “High-resolution fiber-optic bundle
microscopy based on dithered spatial compounding,” Proc. SPIE8938, Optical Fibers and Sensors for
Medical Diagnostics and Treatment Applications XIV, 893811 (February 20, 2014);
doi:10.1117/12.2038690. (Oral presentation & Peer-reviewed conference publication) [Link]
[C-11] Jaepyeong Cha and Jin U. Kang, “Micro sized implantable ball lens-based fiber optic probe
design,” Proc. SPIE8938, Optical Fibers and Sensors for Medical Diagnostics and Treatment
Applications XIV, 893813 (February 20, 2014); doi:10.1117/12.2038439. (Oral presentation & Peerreviewed conference publication) [Link]
[C-10] Brian Triana, Jaepyeong Cha, Azad Shademan, Axel Krieger, Jin U. Kang, and Peter Kim,
“Multispectral tissue analysis and classification towards enabling automated robotic surgery,” Proc.
SPIE 8935, Advanced Biomedical and Clinical Diagnostic Systems XII, 893527 (February 27, 2014);
doi:10.1117/12.2040627. (Peer-reviewed conference publication) [Link]
[C-9] Jaepyeong Cha, Martin Paukert, Dwight E. Bergles, and Jin U. Kang, “Fiber-optic fluorescence
microscopy for functional brain imaging in awake, mobile mice,” Proc. SPIE 8928, Optical Techniques
in Neurosurgery, Neurophotonics, and Optogenetics, 89282N (March 20, 2014);
doi:10.1117/12.2038265. (Oral presentation & Peer-reviewed conference publication) [Link]
[C-8] Jaepyeong Cha, Gyeong Woo Cheon, and Jin U. Kang, “Scanless multicolor fiber-optic
microscopy for real-time mouse brain imaging,” BRAIN ACTIVITY MAP Mini-symposium, Johns
Hopkins Medicine | Brain Science Institute, Baltimore, July 10, 2013. (Poster presentation) [Link]
[C-7] Jaepyeong Cha and Jin U. Kang, “Video-rate multicolor fiber-optic microscopy,” OSA Imaging
and Applied Optics Congress: Imaging Systems and Applications (IS) - IM4E.4, Arlington, June 24,
2013. (Oral presentation & Peer-reviewed conference publication) [Link]
[C-6] Jaepyeong Cha, Martin Paukert, Dwight E. Bergles, and Jin U. Kang, “Fiber-optic fluorescence
microscopy for detecting neural activity in awake, mobile mice,” Student Poster Presentation in Optics
and Photonics, University of Maryland, College Park, April 10, 2013. (Poster presentation)
[C-5] Jaepyeong Cha, Jing Zhang, Saumya Gurbani, Min Li, and Jin U. Kang, “Dual-modality fiberoptic imager (DFOI) for intracellular gene delivery in human cervical cancer cell,” SPIE Photonics West
BIOS 8576-3, San Francisco, Feb 2, 2013. (Oral presentation & Peer-reviewed conference publication)
[Link]
[C-4] Jaepyeong Cha, Saumya Gurbani, Gyeong Woo Cheon, and Jin U. Kang, “Automatic Cell
Counting Using Fiber-optic Fluorescence Endomicroscope,” Hopkins Imaging Conference 2012,
Baltimore, November 16, 2012. (Poster presentation)
[C-3] Jaepyeong Cha, Jing Zhang, Min Li, and Jin U. Kang, “Deep UV Laser-Induced Fluorescence
spectra characterization of fluorescent- cyclotriveratrylene (fCTV) and neurotransmitter Acetylcholine
(ACh),” in The 4th Metropolitan Biophotonics Symposium (MBS'2012), March 19, 2012. (Poster
presentation)
[C-2] Jaepyeong Cha, Kie Bong Nahm and Hee Chan Kim, “A model study for characterization of
optical transcutaneous energy transfer system,” Korean Society of Medical and Biological Engineering
Spring Conference, Chuncheon, Korea, May 14-15, 2010 (Poster presentation)
[C-1] Hyoun-Joong Kong, Jae Pyeong Cha, Jong Mo Seo, and Hee Chan Kim, “Development of Cold
Light Indirect Ophthalmoscopic Video System for Sharing Stereopsis,” Proceedings of the 29th
International Conference of the IEEE Engineering in Medicine and Biology Society in conjunction with
the Biennial Conference of the French Society of Biological and Medical Engineering (SFGBM), August
23-26, Lyon, France, 2007. “Top 10 Articles Published in the Same Domain by BioMedLib“ [Link]
REFERENCES
Available on request