ANDROGEN EXCESS & PCOS SOCIETY 12th ANNUAL MEETING Kauai, HI, USA October 22-23, 2014 Kauai Marriott Resort and Beach Club Kalapaki Beach Lihue, Kauai, HI, USA OCTOBER 22nd, 2014 Time Event/Speaker 2:00 – 6:00 pm Registration Topic 3:00 – 6:00 pm MEET THE PROFESSOR SESSIONS 3:00 – 4:00 pm ELLEN CONNOR, M.D. Pediatric Endocrinology and Diabetes American Family Children’s Hospital University of Wisconsin, Madison, WI, USA CLINICAL PROBLEMS IN DIAGNOSIS OF PCOS DURING ADOLESCENCE JOOP LAVEN, M.D. Department of Obstetrics and Gynecology, Rotterdam University, Rotterdam, The Netherlands CLINICAL PROBLEMS IN TREATMENT OF INFERTILITY IN PCOS 3:00 – 4:00 pm 4:00 – 5:00 pm JUDITH ADAMS, D.M.U. Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA, USA CLINICAL PROBLEMS IN DIAGNOSIS AND TREATMENT OF PCOS CLINICAL PROBLEMS IN DIAGNOSING PCO BY ULTRASONOGRAPHY 4:00 – 5:00 pm SELMA WITCHEL, M.D. Pediatric Endocrinology Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA 5:00 – 6:00 pm ANUJA DOKRAS, M.D. Division of Infertility and Reproductive Endocrinology, University of Pennsylvania, Philadelphia, PA, USA CLINICAL PROBLEMS IN TREATING CV/METABOLIC RISK IN PCOS 5:00 – 6:00 pm RICHARD LEGRO, M.D. Department of Obstetrics and Gynecology, Penn State University, Hershey, PA, USA USE OF AROMATASE INHIBITORS IN TREATMENT OF PCOS 6:00 pm ADJOURN 7:00 – 8:00 pm WELCOME RECEPTION CLINICAL PROBLEMS IN TREATMENT OF PCOS DURING ADOLESCENCE OCTOBER 23rd, 2014 Time Speaker 7:30 – 9:30 am REGISTRATION 8:00 – 8:10 am DAVID ABBOTT, Ph.D. President of AEPCOS Society Topic WELCOME ANUJA DOKRAS, M.D. Chairman of Annual Meeting Committee 8:10 – 9:30 am Session I Chairs: SESSION I: HELENA TEEDE, M.D. Monash Centre for Health Research and Implementation, Monash University, Clayton, Australia 8:10 – 8:30 am LISA MORAN, Ph.D. Department of Obstetrics and Gynecology Robinson Research Institute University of Adelaide, Australia 8:30 – 8:50 am KATHY HOEGER, M.D. Department of Obstetrics and Gynecology, University of Rochester, Rochester, USA 8:50 – 9:10 am DANIEL DUMESIC, M.D. Department of Obstetrics and Gynecology University of California Los Angeles, USA 9:10 - 9:30 am Q&A 9:30 – 10:00 am Chair: OBESITY IN PCOS DIET AND EXERCISE IN PCOS WEIGHT LOSS STRATEGIES AND REPRODUCTION IN PCOS ADIPOGENESIS AND PCOS ANUJA DOKRAS, M.D., Ph.D. Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA PRESIDENTIAL LECTURE 9:30 – 10:00 am DAVID ABBOTT, Ph.D. Department of Obstetrics and Gynecology and Primate Center, University of Wisconsin, Madison, USA DEVELOPMENTAL ORIGINS OF PCOS: INITIATION OR AMPLIFICATION BY FETAL ANDROGEN EXCESS? 10:00 – 10:20 am COFFEE BREAK Session II Chairs: 10:20 – 11:30 am HEATHER HUDDLESTON, M.D. UCSF Center for Reproductive Health,, University of California, San Francisco, USA SESSION II: OVARIAN AND PLACENTAL DYSFUNCTION ASSOCIATED WITH PCOS TERESA SIR PETERMANN, M.D. Department of Endocrinology, University of Chile, Santiago, Chile 10:20 – 10:40 am RAY RODGERS, Ph.D. Department of Obstetrics and Gynecology Robinson Research Institute University of Adelaide, Australia NEW CONCEPTS OF THE NORMAL AND POLYCYSTIC OVARY 10:40 – 11:00 am ELISABET STENER-VICTORIN, Ph.D. Department of Physiology, University of Gothenburg, Sweden HOW DOES PRENATAL AND PREPUBERTAL ANDROGEN EXPOSURE AFFECT PLACENTAL FUNCTION AND DEVELOPMENT OF PCOS PHENOTYPES IN RODENTS? 11:00 – 11:20 am Q&A 11:20 am -12:30 pm Session III Chairs: SESSION III: MARLA LUJAN, PH.D. Department of Obstetrics and Gynecology, Cornell University, Ithaca, NY, USA ORAL COMMUNICATIONS SERGIO RECABARREN, Ph.D Department of Endocrinology, University of Concepcion, Concepcion, Chile 11:20 – 11:30 am BAO HUI LEE Singapore, Singapore IDENTIFICATION OF A NATURAL COMPOUND, X25, AS A POTENTIAL DRUG CANDIDATE FOR THE MANAGEMENT OF HYPERANDROGENISM IN PCOS 11:30 – 11:40 am DONNA VINE, M.D. Edmonton, Alberta, Canada FREE TESTOSTERONE AND IMPAIRED INSULIN SENSITIVITY ARE POSITIVELY CORRELATED WITH PLASMA TRIGLYCERIDES and APOB48-REMNANT LIPOPROTEINS IN OBESE ADOLESCENTS WITH PCOS. 11:40 – 11:50 am NATHALIE DEGAIFFIER, M.D. Philadelphia, PA, USA 11:50 am – 12:00 pm ASHRAF GANIE, M.D. Delhi, India RACIAL DISPARITIES IN CARDIOMETABOLIC RISK IN WOMEN WITH PCOS VITAMIN D SUPPLEMENTATION POTENTIATES THE CLINICAL BENEFITS OF METFORMIN AND PIOGLITAZONE IN INDIAN WOMEN WITH PCOS 12:00 – 12:10 pm MOLLY QUINN, M.D. San Francisco, CA, USA 12:10 – 12:30 pm Q&A 12:30 – 1:15 pm Session IV Chair: RICHARD LEGRO, M.D. Department of Obstetrics and Gynecology, Penn State University, Hershey, PA, USA 12:30 – 1:00 pm FRANK STANCZYK, Ph.D., Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA, USA RAISING THRESHOLD FOR DIAGNOSIS OF PCOS MISSES POPULATION OF PATIENTS AT RISK FOR METABOLIC DYSFUNCTION SESSION IV: DEBATE: HOW SHOULD WE MEASURE SERUM TESTOSTERONE? ADVANTAGES AND DISADVANTAGES OF LC/MS METHODOLOGY NIGEL CLARKE, Ph.D. Quest diagnostics, San Juan Capistrano, CA, USA 1:00 – 1:15 pm Q&A 1:15 – 2:30 pm LUNCH AND POSTER SESSION 2:30 – 3:45 pm Session V Chairs: SESSION V: WALTER FUTTERWEIT, M.D. Mount Sinai Hospital, New York, NY, USA CVD RISK IN PCOS CARLOS MORAN, M.D. Mexican Institute of Social Security, Mexico City, Mexico 2:30 – 2:50 pm NEHAL MEHTA, M.D., Section of Inflammation and Metabolic Diseases, National Health Institute, Bethesda, MD, USA 2:50 – 3:10 pm DAVID EHRMANN, M.D. Department of Medicine, University of Chicago, Chicago, USA 3:10 – 3:30 pm ANTONI DULEBA, M.D. Department of Obstetrics and Gynecology University of California, San Diego, USA 3:30 – 3:45 pm Q&A CHRONIC INFLAMMATION AND CARDIOMETABOLIC DISORDERS PCOS AND OBSTRUCTIVE SLEEP APNEA: CHANCE ASSOCIATION OR CAUSAL LINK? STATINS AND PCOS 3:45 – 4:10 pm COFFEE BREAK Session VI Chair: 4:10 – 4:40 pm SESSION VI: DAVID ABBOTT, Ph.D. Department of Obstetrics and Gynecology and Primate Center, University of Wisconsin, Madison, USA 4:10 – 4:40 pm ROBERT NORMAN, M.D. Department of Obstetrics & Gynecology, University of Adelaide, Australia 4:40 – 5:50 pm Session VII Chair: ASHRAF GANIE, M.D. All India Institute of Medical Sciences, Delhi, India KEYNOTE LECTURE “PREPARING FOR PREGNANCY – BASIC BIOLOGY THROUGH TO DELIVERY OF HEALTH SERVICES FOR WOMEN WITH PCOS” SESSION VII: ORAL COMMUNICATIONS TANIA BURGERT, M.D. Children's Mercy Hospital, Kansas City, KS, USA 4:40 – 4:50 pm DARIA LIZNEVA, M.D. Samara, Russian Federation 4:50 – 5:00 pm HASINA MAREDIA, Ph.D. Providence, RI, USA UNDERSTANDING THE DISTRIBUTION AND CLINICAL FEATURES OF POLYCYSTIC OVARIES USING AMH AMONG SAMOAN WOMEN 5:00 – 5:10 pm SAMANTHA BUTTS, M.D. Philadelphia, PA, USA CAN AMH LEVELS PREDICT CARDIOMETABOLIC RISK IN WOMEN WITH PCOS? 5:10 – 5:20 pm JAE HO LEE, M.D. Seoul, South Korea 5:20 – 5:30 pm CHANG WOO CHOO, M.D. Seoul, South Korea 5:30 – 6:30 pm Session VIIi Chair: ENRICO CARMINA, M.D. Endorcinology Unit, University of Palermo, Palermo, Italy PREVALENCE OF SUBPHENOTYPES IN WOMEN WITH PCOS IDENTIFIED IN CLINICAL VS. UNSELECTED POPULATIONS THE EFFICACY OF AROMATASE INHIBITOR IN PCOS WOMEN WITH A POOR ENDOMETIAL RESPONSE TO CLOMIPHENE CITRATE THE COMPARISON OF THE EFFICACY BETWEEN HMG AND FSH IN PCOS WOMEN UNDERGOING IVF SESSION VIII PRESENTATION AND TREATMENT OF PCOS IN NORTH EAST ASIA 5:30 – 5:45 pm MING I HSU, M.D. Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan 5:45 – 6:00 pm JIE QIAO, M.D. Department of Obstetrics and Gynecology, Peking University 3rd Hospital, Beijing, China 6:00 – 6.15 pm XIAOKE WU Department of Obstetrics and Gynecology, First Affiliated Hospital, Heilongjiang University, Harbin, China 6:15 – 6:30 pm 6:30 pm 6:30 – 7:00 pm CARDIOMETABOLIC RISK IN TAIWANESE PCOS POPULATION PREVALENCE AND CHARACTERS OF POLYCYSTIC OVARY SYNDROME IN WOMEN IN CHINA: A LARGE COMMUNITY-BASED STUDY THE EFFECTS OF CHINESE HERBAL MEDICINE ON METABOLIC FUNCTION IN PCOS Q&A ADJOURN Chair: ENRICO CARMINA, M.D. Executive Director Androgen Excess & PCOS Society PRESENTATION OF NEW AEPCOS PRESIDENT BUSINESS MEETING Accreditation Statement This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Wisconsin School of Medicine and Public Health, Office of Continuing Professional Development, Department of Obstetrics and Gynecology and Androgen Excess and PCOS Society. The University of Wisconsin School of Medicine and Public Health is accredited by the ACCME to provide continuing medical education for physicians. This activity has been approved for AMA PRA Category 1 Credit™. Policy on Disclosure It is the policy of the University of Wisconsin School of Medicine and Public Health that anyone with a CME planning role for this activity (persons who may influence content) disclose all relevant financial relationships with commercial interests* in order to allow CME staff to identify and resolve any potential conflicts of interest. Disclosure of any planned discussions of unlabeled/unapproved uses of drugs or devices during each presentation is required. Detailed disclosure information will be made available in the handout materials.