Acute appendicitis in relation to pregnancy Features, diagnosis, management and outcomes of all cases at Landspitali University Hospital in Iceland 19942010 Thorhallsdottir H, Valsdottir EB, Bjarnadottir RI, Strandell A. VECKAN 2015 • Redovisning av intressekonflikter/jäv: • Det finns inga intressekonflikter eller jäv att redovisa. Aims To analyze acute appendicitis in pregnant and early postpartum Icelandic women: Incidence, diagnosis, management and outcomes If time from admission to surgery influenced the risk of having a perforated appendicitis and subsequent complications Pregnant patients with suspected appendicitis Pregnant patients 44 Acute surgery 42 No appendectomy 5 Appendectomy 37 Positive histology 31 Negative histology 6 Antibiotics 2 Non-surgical explanation 3 *emergency surgery on fetal indication Gynaecological pathology 2 Cesaerian section* two weeks later. No appendectomy 1 No signs of appendicitis at surgery 1 Elective surgery 1 Positive histology 1 Table 1: Primary surgical approaches for appendectomy in the pregnant population Total number of patients Acute surgery Laparoscopy Laparotomy Caesarean section n=44 n=42 n=33 n=8 n=1 1st trimester 16 16 15 1 . 2nd trimester 21 20 14* 6 0 3rd trimester 7 6 4 1 1 Gestational age Frequency distribution across trimesters of all pregnant patients with suspected appendicitis (n=44), presented by histological, surgical and clinical findings. 24 22 20 18 no surgery 16 14 negative histology 12 no appendendicitis/appendecto my at surgery 10 8 positive histology 6 4 2 0 1st 2nd 3rd The relationship between time from admission to surgery and perforation of the appendix (n=42) Mann-Whitney U test, p = 0.04 Discussion Styrkor / svagheter • Samtliga med suspekt • Ändå ett litet material appendicit under 17 år • Ingen kontrollgrupp • Ett center som täcker • Saknas data på 73% av alla födslar på symptomduration Island Conclutions Incidence 0.63 per 1000 births Laparoscopy - most common surgical approach across all trimesters Perforated appendicitis associated with: increased time from admission to surgery increasing gestational age Major complications: premature delivery and perinatal death
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