Directory of Services
Directory of Services General Laboratory Information Specimen Collection and Preparation Specimen Transportation Anatomic Pathology Specimens Cytology Specimens Hemostasis/Thrombosis Specimens Microbiology Specimens Molecular Diagnostics Specimens Critical Value Policies Test List Changed Test History Index by Test Title Index by Order Code 11/19/2014 Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Section 7 Section 8 Section 9 Section 10 Section 11 Section 12 Section 13 BBPL Directory of Services General Laboratory Information Administration: Officers & Directors Medical Director ..................................................................................................... Michael D. Curry, MD, PhD General Manager ....................................................................................................................... Richard Cotten Director of Accounting ................................................................................................................. Roger Asbury Director of Clinical Laboratory (Chemistry, Hematology, Immunology & Microbiology) William Thornton, PhD Director of Corporate Compliance.............................................................................................. Cathy Thornton Director of Corporate Development.................................................................................................. Joe Sanford Director of Human Resources ............................................................................................................ Kelly Poor Vice President Marketing & Sales .................................................................................................. Brian Barnett S1 Departmental Directory: Accounts Payable Anatomic Pathology/Transcription Business Office Billing Customer Service Business Development Chemistry Client Services Cytology Data Management Histology Human Resources Information Technology/Data Processing Long-Term Care Operation Manager Maintenance Materials Management Medical Director Assistant Microbiology Molecular Diagnostics Patient Service Center Manager Processing/Specimen Management Safety & Education Supplies Carol Samuels Donna Wagner Sheila Libbert Ronald Holtkamp Brian Barnett Michael Novak Jessica Howell Cindy Kemper Linda Wood Steve Weaver Debbie Grigery Tad Reissing Joy Peek Danny Galbreath Keith Fernandez Mitzi McLaren Joanne Reed Pat Zeitlow Jennifer Murphy Melissa Jennings Diana Inman Licensure & Accreditations: Clinical Laboratory Improvement Amendments (CLIA ) College of American Pathologists (CAP) 1-1 573-886-4612 573-886-4619 573-886-4618 573-886-4610 417-569-4147 573-886-4534 800-786-4602/ 573-886-4620 573-886-4698 573-886-4643 573-886-4677 573-886-4605 573-886-4524 573-886-4540 573-886-4675 573-886-4607 573-886-4608 573-886-4690 573-886-4689 573-886-4533 573-886-4663 573-886-4658 800-786-4602/ 573-886-4620 ID Numbers: 26D0652373 19446-01 General Laboratory Information BBPL Directory of Services Robert F. Cheek, M.D. Associate Medical Director, Central Reference Laboratory Laboratory Medical Director, Cooper County Hospital Anatomic & Clinical Pathology Dermatopathology Adam T. Clapper, M.D. Associate Pathologist, Boone Hospital Center Laboratory Medical Director, Landmark Hospital Anatomic & Clinical Pathology Michael D. Curry, M.D., Ph.D. Medical Director, Central Reference Laboratory Anatomic & Clinical Pathology Molecular & Biochemistry Diagnostics Grant Van Dyke Darkow, M.D. Laboratory Medical Director, Boone Hospital Center Anatomic & Clinical Pathology Jack D. Jones, M.D. Associate Pathologist, Central Reference Laboratory Anatomic & Clinical Pathology Lynn L. Kleopfer, M.D. Laboratory Medical Director, Samaritan Memorial Hospital Anatomic & Clinical Pathology Cytopathology Chadwick L. Linder, M.D. Laboratory Medical Director, Capital Region Medical Ctr Anatomic & Clinical Pathology Paul J. McGowan, M.D. Associate Pathologist, Central Reference Laboratory Anatomic & Clinical Pathology Hematopathology Leslie K. Miller, M.D. Associate Pathologist, Central Reference Laboratory Anatomic & Clinical Pathology Laboratory Medical Director, Audrain Medical Center, Callaway County Hospital, Jefferson City Medical Group, and Pershing Health System Anatomic & Clinical Pathology James T. Edinger, M.D. R. Gideon Morrison, M.D. Alberto A. Diaz-Arias, M.D. Associate Pathologist, Central Reference Laboratory Anatomic & Clinical Pathology Dermatopathology & Hematopathology Laboratory Medical Director, Ozarks Medical Center Anatomic & Clinical Pathology T. Bart Shaw, M.D. Laboratory Medical Director, Northeast Regional Medical Ctr. Anatomic & Clinical Pathology Laboratory Medical Director, Fitzgibbon Hospital, Moberly Regional Medical Center, Salem Memorial Hospital & Texas County Memorial Hospital Anatomic & Clinical Pathology Belinda R. Fender, M.D. Denise M. Tritz, M.D. Maria L. Evans, M.D. Associate Pathologist, Central Reference Laboratory & Northeast Regional Med Center Anatomic & Clinical Pathology Hematopathology Steven J. Haas, M.D. Laboratory Medical Director, Lake Regional Health System Anatomic & Clinical Pathology Laboratory Medical Director, St. Mary’s Health Center Anatomic & Clinical Pathology Helena Wang, M.D. St. Mary’s Health Center Anatomic Pathology Cytopathology Lawrence D. Henry, M.D. Associate Pathologist, St. Mary’s Health Center Anatomic & Clinical Pathology Cytopathology, Anatomic & Forensic Pathology Dennis L. Johnson, M.D., Ph.D. Laboratory Medical Director, Bothwell Regional Hlth Cen. Anatomic & Clinical Pathology Immunopathology, Hematology General Laboratory Information 1-2 S1 BBPL Directory of Services History: Boyce & Bynum Pathology Laboratories, P.C. (BBPL) was founded in 1965 by John M. Boyce, MD and William R. Bynum, MD. The vision was cast from a desire to better resource small hospital laboratories and to provide affordable technology not available in this area. Boyce & Bynum has grown to a twenty (20) member professional group with pathologists living in West Plains, Mexico, Sedalia, Jefferson City, and Columbia. We are a full-service laboratory providing services in chemistry, hematology, microbiology, immunology, molecular diagnostics, anatomic pathology, cytology and histology. Our main reference laboratory is located in Columbia, Missouri and is supported by Patient Service Centers in Columbia, Fulton, Jefferson City, Kansas City, Moberly, Sedalia, Springfield, and West Plains, Missouri, as well as, Little Rock, Arkansas and Oklahoma City, Oklahoma. S1 Boyce & Bynum is proud of the following accomplishments: Formulated the concept of “cluster labs” as early as 1965 Pioneer in the field of independent laboratory development Greater than 45 years of pathology reference laboratory service Long-standing tradition of excellence and commitment to physicians of mid-Missouri Expansion of service; 52,000 square feet of laboratory space Responsive to client needs with laboratory service tailored to a specific small marketplace Boyce & Bynum offers a wide spectrum of professional knowledge to the hospitals and the outpatient community served. In-house consultation and shared travel allows each hospital to receive full benefits of a multi-specialty group. Because of this approach to providing professional services, Boyce & Bynum has been capable of assisting hospital laboratories in both The Joint Commission and College of American Pathologists accreditations, as well as providing routine pathology services to hospitals and medical staff. Boyce and Bynum currently serves an outpatient community of 100,000+ and pathology service is provided to many hospitals in the central area of the state between St. Louis and Kansas City. Audrain Medical Center, Mexico, Missouri Boone Hospital Center, Columbia, Missouri Bothwell Regional Health Center, Sedalia, Missouri Callaway Community Hospital, Fulton, Missouri Capital Region Medical Center, Jefferson City, Missouri Cooper County Memorial Hospital, Boonville, Missouri Fitzgibbon Memorial Hospital, Marshall, Missouri Hermann Area District Hospital, Hermann, Missouri Jefferson City Medical Group, Jefferson City, Missouri Lake Regional Health System, Osage Beach, Missouri Moberly Regional Medical Center, Moberly, Missouri Northeast Regional Medical Center, Kirksville, Missouri Ozarks Medical Center, West Plains, Missouri Pershing Memorial Hospital, Brookfield, Missouri Putnam County Memorial Hospital, Unionville, Missouri Salem Memorial Hospital, Salem, Missouri Samaritan Hospital, Macon, Missouri Scotland County Memorial Hospital, Memphis, Missouri St. Mary’s Health Center, Jefferson City, Missouri Sullivan County Memorial Hospital, Milan, Missouri Texas County Hospital, Houston, Missouri University of Missouri Healthcare, Columbia, Missouri Services: Full service laboratory Couriers - convenient pick-up Connectivity services Billing options Drug Screen (NIDA) collection Phlebotomy instruction 1-3 General Laboratory Information BBPL Directory of Services Interpretation of laboratory results and recommendations for follow-up testing Client specific test panels Reflexive testing Test result call-backs Continuous Quality Improvement program Pre-inspection consultation Technical consultation Management consultation Assistance with current and future regulatory compliance Newsletter Video library Occupational health programs S1 Our main focus is to provide referring physicians with accurate test reporting. Our skilled and experienced medical technologists, along with state of the art technology and reagents, ensure that stringent quality control procedures are enforced and maintained at all times. Boyce & Bynum Laboratories P.C. participates in the Proficiency Testing Program from the College of American Pathologists (CAP), AAB and CytoQuest. Clinically abnormal results, which may be significant, are reviewed by the Department Supervisor and a Pathologist prior to reporting. Critical values are called immediately so patients may receive the necessary medical treatment as soon as possible. We are accredited by the College of American Pathologists and licensed by the Federal Government for the Medicare program. Most of the routine testing is performed at our central reference laboratory facility in Columbia, Missouri. Esoteric testing is referred to ARUP (Associated Regional & University Pathologist in Salt Lake City, Utah), LabCorp (Laboratory Corporation of America in Burlington, North Carolina) and to the University of Missouri – Columbia, Missouri. Client Services/Courier Network: Boyce & Bynum’s Client Services Department will be the major source of information for you. Employees in Client Services are trained to respond to client needs such as result inquiries, unlisted test information, technical questions, and specimen requirements. Client Services operates on a work schedule conducive to client needs and are available by calling a direct toll free number, 1-800-786-4602. Physician inquiries may be directed to our pathologists if desired. Boyce & Bynum will provide at no cost specimen containers, requisitions, Directory of Services with instructions for processing specimens, specimen collection tubes, PAP supplies and courier bags. Boyce & Bynum arranges for courier services to retrieve specimens from our clients through out our service area in Missouri, Northern Arkansas, and Eastern Kansas. Pickups are arranged to accommodate the client needs. The professional couriers are trained in proper handling and transportation of medical specimens in accordance with state and federal regulations. Connectivity Services: Boyce & Bynum Pathology Laboratories understands the value of information system integration and has the technology and resources to facilitate communications with a variety of applications and platforms. In addition to interface solutions, BBPL’s Laboratory Information System also provides state of the art test ordering and result reporting to our clients. Upon completion of testing, test results are reported to the client and are available 24/7 on our secure web portal. For more information about BBPL’s connectivity services, contact your BBPL client support representative. General Laboratory Information 1-4 BBPL Directory of Services Billing & CPT Coding: Each month the client will receive an itemized invoice/statement which will indicate the date of service, patient name, CPT code, test name, and test charge. S1 CPT Coding: It is the responsibility of the client to determine correct CPT codes to use for billing. While this catalog lists CPT codes in an effort to provide some guidance, CPT codes listed only reflect our interpretation of CPT coding requirements and are not necessarily correct. The client should verify accuracy of codes listed, and where multiple codes are listed, should select codes for tests actually performed on the specimen. Boyce & Bynum Pathology Laboratories assumes no responsibility for billing errors due to reliance on CPT codes listed in this catalog. For further reference, please consult the CPT Coding Manual published by the American Medical Association. Reflex Testing: Boyce & Bynum Pathology Laboratories offers tests that reflex to additional follow-up tests when medically appropriate. In many cases, BBPL offers components of reflex tests individually as well as together. Clients should familiarize themselves with the reflex test offerings and make a decision whether to order a reflex test or an individual component. Continuous Quality Improvement Program: Boyce & Bynum Pathology Laboratories has an extensive Continuous Quality Improvement (CQI) program. Our program builds upon the concepts of quality control and quality assurance providing an opportunity to deliver consistent, high-quality and cost-effective service to our clients. In addition, our CQI program enhances our ability to meet and exceed the requirements of regulatory/accreditation agencies and provide quality service to our clients. A core principle at Boyce & Bynum Pathology Laboratories is the continuous improvement of all processes and services that support the care of patients. In addition, our CQI processes focus on meeting the needs of our clients, to help them serve their patients. The policies, processes, and procedures associated with the CQI program can be applied to all operations of workflow (e.g., pre-analytical, analytical, and post-analytical). Performance is measured through surveys, audits, proficiency testing, and constant monitoring of internal and external quality indicators. Data generated by these quality measurements drives process improvement initiatives to seek resolutions to system-wide problems. Boyce & Bynum participates in the Proficiency Testing Program from the College of American Pathologists (CAP), AAB and CytoQuest. We conduct internal assessments and comparability studies to ensure the accuracy and reliability of patient testing when an approved proficiency testing program is not available or additional quality monitoring is desired. Technical Assistance: Technical assistance is available to clients of Boyce & Bynum Pathology Laboratories, P.C. We have many qualified registered medical technologists available to provide this service. These individuals can assist with problem solving and procedural advice on a requested basis. BBPL Policies: Business Continuity and Contingency Planning: In the event of a disaster, Boyce & Bynum Pathology Laboratories, P.C. (BBPL) has a comprehensive contingency plan in place to ensure that the impact on laboratory practice is minimized. Compliance Policies: Boyce & Bynum Pathology Laboratories, P.C. (BBPL) is committed to compliance with applicable laws and regulations such as the Clinical Laboratory Improvement Amendments (CLIA). Regulatory agencies that oversee our compliance include, but are not limited to, the Centers for Medicare and Medicaid Services (CMS), and the Department of Transportation (DOT). 1-5 General Laboratory Information BBPL Directory of Services BBPL develops, implements, and maintains policies, processes, and procedures throughout our organization which are designed to meet relevant requirements. We expect clients utilizing our services to ensure their own compliance with patient confidentiality, diagnosis coding, anti-kick back statutes, professional courtesy, CPT-4 coding, CLIA proficiency testing, and other similar regulatory requirements. S1 Confidentiality of Results: Boyce & Bynum Pathology Laboratories, P.C. (BBPL) is committed to maintaining confidentiality of patient information. To ensure Health Insurance Portability and Accountability Act of 1996 (HIPAA) compliance for appropriate release of patient results, BBPL has adopted the following policies: Phone Inquiry Policy—One of the following unique identifiers will be required: BBPL accession ID number for specimen; or Client account number from BBPL along with patient name; or Client accession ID number interfaced to BBPL or Identification by individual that he or she is, in fact, the “referring physician” identified on the requisition form for the BBPL client. Under federal regulations, we are only authorized to release results to ordering physicians or health-care providers responsible for the individual patient’s care. We appreciate your assistance in helping BBPL preserve patient confidentiality. Provision of appropriate identifiers will greatly assist prompt and accurate response to inquires and reporting. HIPAA Compliance: Boyce & Bynum Pathology Laboratories, P.C. (BBPL) is fully committed to compliance with all privacy, security, and electronic transaction code requirements of the Health Insurance Portability and Accountability Act of 1996 (HIPAA). All services provided by BBPL that involve joint efforts will be done in a manner which enables our clients to be HIPAA and The College of American Pathologists (CAP) compliant. Proficiency Testing: Boyce & Bynum Pathology Laboratories, P.C. is a College of American Pathologists (CAP)-accredited, CLIAlicensed facility that voluntarily participates in many diverse external and internal proficiency testing programs. It is BBPL’s expectation that clients utilizing our services will adhere to CLIA requirements for proficiency testing (42 CFR 493.801), including a prohibition on discussion about samples or results and sharing of proficiency testing materials with BBPL during the active survey period. Referring of specimens is acceptable for comparison purposes when outside of the active survey period or when an approved proficiency testing program is not available for a given analyte. Reportable Diseases: BBPL endeavors to comply with laboratory reporting requirements for each state health department regarding reportable diseases. We strive to cooperate with our clients so that we both comply with state regulation General Laboratory Information 1-6 BBPL Directory of Services Specimen Collection and Preparation Introduction: The laboratory must have a written or electronic request for patient testing from an authorized person. The quality of results from laboratory testing depends greatly on the proper collection and handling of the specimen submitted for analysis. Correct patient preparation, specimen collection, specimen labeling, specimen packaging and transportation are essential factors for quality results. S2 Specific specimen requirements for each determination, including sample size, are provided in the BBPL Directory of Services Test section. To avoid additional expense and inconvenience, please make sure that you have submitted at least the quantity specified for the test requested. Specimen Labeling: All specimens submitted to Boyce & Bynum Pathology Laboratories, P.C. (BBPL) for testing must be appropriately labeled. This requirement assures positive identification and optimum integrity of patient specimens from the time of collection until testing is complete and results reported. The College of American Pathologists requires that all specimens must be labeled with two (2) identifiers at the time of collection. Ideally, a name-number system is desirable so that there are at least 2 person specific identifying items on each sample. Person-specific identifiers may include accession number, patient’s first and last name or patient’s initials, unique identifying number (e.g., medical record number), or date of birth. When insufficient or inconsistent identification is submitted, BBPL may recommend that a new specimen be obtained if feasible. Blood Components: Different blood components are used depending on the test ordered. Specimen requirements will specify whether serum, plasma, or whole blood should be submitted and how to obtain the specific component needed for testing. Whole blood is obtained by collecting blood in a vacuum tube with an anticoagulant. To prevent clots from forming, thorough mixing of blood with the anticoagulant is necessary. Gently invert tube (do not shake) four to eight (4-8) times (depending on the specimen tube being used) immediately after collection. Do not freeze unless specified for the specimen handling requirements. Plasma is the liquid portion of the blood in which particulates such as platelets and fibrinogen, a clotting protein, are present. Plasma normally appears as a hazy yellowish liquid and is obtained by centrifugation when blood is drawn in a tube containing an anticoagulant. The tube should be gently inverted immediately at least four to eight (4-8) times depending on the specimen tube used. Separate the cells within one-half hour by centrifugation and transfer the plasma into a clean vial for delivery to the laboratory. Serum is the cell-free portion of blood from which the fibrinogen and particulate components have been separated in the process of clotting. Serum usually appears as a clear yellowish liquid and is obtained by centrifugation after the blood clots. Draw a full 7 mL gel-barrier tube for each 2 mL of serum required. Special processing techniques are explained in the section “Order of draw”. Collection Tube Types/ Transport tubes: BBPL provides special vacuum tubes, containers and transport tubes for collection and transport of specimens. Vacuum tube stoppers are color-coded and each color has a corresponding use and/or additive. Check which tubes need to be drawn in the BBPL Directory of Services by each test and profile. To provide the most accurate results, it is necessary to use the indicated tube(s) for the requested test(s). The following are general guidelines for processing the various vacuum tubes. More specific instructions are listed in the specific test requirement section. Be sure to submit the specific blood component listed under "Preferred Specimen." Order of draw: To prevent contamination of tubes with additives from other tubes, it is important to draw tubes in a specific order called “the order of the draw”. The sequence of collection of evacuated tubes in a multi-draw should be in this order: 2-1 Specimen Collection and Preparation BBPL Directory of Services Clear or WhiteTop Tube: Non-additive tube (no clot activator in tube). Waste tube. Fill before filling blue-top tube when using butterfly set. Light Blue Top Tube: Contains sodium citrate as an anticoagulant. Fill completely and invert three to six (3-6) times in order to facilitate mixing. S2 Gel-Barrier Tube: Contains no anticoagulant and is to be used for the collection of serum. Also known as serum separator tubes (SST) or gel separator tubes. A gel substance is present at the bottom of the tube, which upon centrifugation moves upward to the serum clot interface. The gel then acts as a barrier between the serum and the cells until the serum can be transferred for transport. Plastic gel-barrier tubes contain a clot activator. Red Top Tube: Contains no anticoagulant and yields serum. Plastic red top tubes contain a clot activator. Green Top Tube: Contains sodium or lithium heparin as an anticoagulant. After tube has been filled, invert eight (8) times in order to facilitate mixing. Refer to specimen requirements for the type of heparin that is acceptable. Lavender Top Tube: Contains ethylenediamine-tetraacetic acid (EDTA) as an anticoagulant. Fill completely and invert eight (8) times in order to facilitate mixing. Yellow Top Tube: Contains ACD anticoagulant (type A or B). Refer to specimen requirements for the type of ACD that is acceptable. Gray Top Tube: Contains sodium fluoride as a preservative and potassium oxalate as an anticoagulant. After tube has been filled with blood, immediately invert eight (8) times in order to facilitate mixing. Please follow these instructions when using the gel-barrier tube: 1. Collect blood specimen using the normal venipuncture technique. Fill tube completely. Invert the tube gently. 2. Allow to stand at room temperature for 30 minutes to clot. Never allow serum to remain on cells more than two hours before centrifugation as chemical changes may occur, which could render some results invalid. 3. Centrifuge for 15 minutes until the serum is free of cells. 4. Remove from centrifuge. Barrier will have formed. Verify that the gel has formed a complete barrier. 5. Allow tube to remain upright for a minimum of 15 minutes to allow gel barrier to adhere to plastic tube wall. 6. If a complete barrier has not formed in the tube, transfer the clear serum to a plastic transport vial for transport to the laboratory. To obtain plasma or serum without using gel-barrier tubes, follow these instructions: 1. Draw 12 mL of blood for each 5 mL serum or plasma needed. Collect in an appropriate collection tube. 2. If serum is required, allow sample to clot for at least 30 minutes before centrifugation. 3. Centrifuge all samples within 1 hour of collection at 2200-2500 RPM for at least 10 minutes. 4. Pipet the serum or plasma into a clean plastic transport vial and attach the label. Do not transfer red cells to the vial. Specimen Collection and Preparation 2-2 BBPL Directory of Services Royal Blue Top Tube: This tube is designed for collection of specimens for trace elements testing. Royal blue top tubes are available with EDTA, heparin and without anticoagulant. Refer to individual tests for specific requirements. Royal blue top tubes with EDTA should be drawn right before the lavender top tube and royal blue top tubes with heparin should be drawn right before the green top tube. Royal blue top tubes with no additive should be drawn before a gel-barrier tube or red top tube. S2 Transport Tubes: Standard plastic transport tube: These containers have been evaluated and are not known to cause analytical interference in the associated assays. The tube’s threaded cap provides a leak-proof seal when screwed on properly. Amber Transport Tubes: Amber transport tubes are provided for specimens that require protection from light. If amber tubes are unavailable, the standard transport tube should be completely wrapped in aluminum foil, top and bottom and the patient’s name placed directly on the transport tube and on the outside aluminum foil. Frozen Specimens: Important Note for Frozen Specimens: For tests requiring frozen serum or plasma, remove the serum or plasma from cells and transfer into a plastic transport vial. Specimens should be frozen as soon as possible after centrifugation and separation. If more than one test is requested on a frozen specimen, please split the specimen prior to freezing and submit separately. Indicate if specimen is plasma on transport tube and test request form (eg. “Plasma, Sodium Citrate”, “Plasma, EDTA”). Do not freeze glass vacuum tubes. Blood Smears: To obtain the best possible specimens for leukocyte differentials, we request that blood smear slides be made at the time of collection. By following this procedure, red cell morphology is preserved and the deterioration of platelets and white cells is prevented. Blood smears may be made from either a fingerstick specimen or the blood drawn into a lavender top tube. Clean slides must be used for making the smears. Contact your laboratory marketing representative if you would like assistance in blood smear preparation. Urine: Random Urine: The normal composition of urine varies considerably during a 24-hour period. Most reference values are based on analysis of the first urine voided in the morning. This specimen is preferred because it has a more uniform volume and concentration, and its lower pH helps preserve the formed elements. To reduce contamination, the specimen submitted for urinalysis should be a clean catch "midstream sample." Submit a first morning specimen whenever possible. Urine for pregnancy testing should be a first morning voiding or a random specimen with a specific gravity of at least 1.010. Note the time of collection of the specimen on the test request form and on the label of the container. If a frozen specimen is required, freeze the urine immediately after collection. Pack in dry ice for shipment to the laboratory. 24-Hour Urine: Because proper collection and preservation of 24-hour urine specimens are essential for accurate test results, patients should be carefully instructed in the correct procedure. Printed instructions for the patient are available from the laboratory. Note: For those analyses requiring the addition of 6N HC1, add the acid at the start of collection. Have the patient collect each voiding in a smaller container and carefully pour the urine into the 24-hour container to avoid any possible acid burns to the patient. Be sure to mix the urine thoroughly before removing the aliquot. Follow these instructions if someone other than the patient is to collect the urine: 2-3 Specimen Collection and Preparation BBPL Directory of Services 1. Follow the physician’s directions regarding food, drink, or drugs before and during collection. 2. During the collection period, place the 24-hour urine container provided by Boyce and Bynum in a refrigerator or cool place, to prevent growth of microorganisms and possible decomposition of urine constituents. 3. On the day of collection, have the patient empty his/her bladder in the morning into the toilet (not to be included in the 24-hour collection). Write the date and time of this voiding on the container and label as the “start” date and time. 4. Collect the patient's next voiding and add it as soon as possible to the 24-hour container. 5. Add all subsequent voidings to the container as in (4). The last sample collected during the 24-hour period should be the first specimen voided the following morning at the same time as the previous morning's first voiding. Record the date and time of this last voiding on the container and label as “finish”. 6. Mix the contents of the container gently but thoroughly. homogeneous. 7. Measure the total volume. 8. Transfer the required aliquot to the screw-cap plastic urine containers provided by Boyce and Bynum. Add any additional required preservative and mix well. 9. Record the 24-hour urine total volume and hours of collection on the specimen container and on the test request form before sending to the laboratory. S2 Examine to ensure that the contents appear 10. Refrigerate the aliquot until it can be sent to the laboratory. For frozen specimens, freeze before packing in dry ice for shipment. If the patient is to collect the urine, give the patient the clean, labeled container provided by Boyce and Bynum, and instruct him/her not to remove any preservatives (powder, liquid or tablet) that may be in the container. Alert the patient that the preservatives are hazardous chemicals. 1. The patient should follow their physician’s directions regarding food, drink, or drugs before and during collection. 2. Have the patient carry out steps 3-5 above and submit the 24-hour collection in the container. Feces: Carefully read the specimen requirements for special patient preparation and fecal specimen collection and handling. Special containers and aliquot containers for the collection and processing of fecal specimens are supplied by Boyce & Bynum Pathology Laboratories. Guidelines for stool collection of timed specimens: 1. Review special specimen requirements with the patient, such as collection duration and diet requirements or restrictions. 2. Collect timed specimens in a pre-weighed, well-sealed container. Do not collect in metal cans. 3. Determine weight of total sample. 4. Mix contents of timed sample well to obtain a homogeneous mixture. 5. Transfer the required aliquot to a clean screw-cap plastic container and seal well. Specimen Collection and Preparation 2-4 BBPL Directory of Services 6. Record the total weight and collection time of the sample on both the sample container and the test request form. Do not send the entire collection unless instructions for specific test indicate otherwise. Common Causes of Unacceptable Specimens: S2 Hemolysis: Hemolysis occurs when the membrane surrounding red blood cells is disrupted and hemoglobin and other intracellular components escape into the serum or plasma. Hemolyzed serum or plasma varies in color from faint pink to bright red, rather than the normal straw color. Grossly or moderately hemolyzed specimens may be rejected and even slight hemolysis will alter certain test results. Hyperbilirubinemia: Icteric serum or plasma varies in color from dark to bright yellow, rather than the normal straw color. Icterus may affect certain determinations. Upon receipt of such specimens, we may request a new sample to assure results of diagnostic value. Turbidity (Lipemia): Turbid, cloudy, or milky serum (lipemic serum) may be produced by the presence of fatty substances (lipids) in the blood. Bacterial contamination may also cause cloudy serum. Moderately or grossly lipemic specimens may alter certain test results. A recent meal produces transient lipemia; therefore, we recommend that patients fast 14-16 hours before a blood specimen is obtained. Radioisotope interference: Diagnostic procedures or therapy involving radioactive compounds may invalidate radioisotope assays. Please obtain specimens for anticipated radioisotope assays before administering isotopes to patient. Please indicate on the test request form if radioisotopes have been administered before specimen was obtained. 2-5 Specimen Collection and Preparation Specimen Transportation BBPL Directory of Services Boyce & Bynum Pathology Laboratories, P.C. (BBPL) recognizes the importance of specimen integrity. Packing methods and shipping guidelines are important in assuring quality patient care and maintaining result integrity by providing for and achieving optimum environmental control during transit. Specimen pickup and transport to BBPL are managed by BBPL’s Processing Department. In order to optimize specimen integrity, BBPL provides supplies to clients to facilitate proper specimen collection and transport. BBPL monitors the shipping regulations of medical specimens established by the International Air Transport Association (IATA) and the Department of Transportation (DOT) to remain in compliance. S3 Specimen Transportation Container Validation: All specimen containers supplied by BBPL for specimen transport withstand stringent testing by the manufacturer to ensure that they are well constructed and have secure lids that prevent leakage during transport. The manufacturer states that the product complies with regulations and meets the shipping requirements of the Department of Transportation‘s 49 CFR 178.605, Dangerous Goods Regulation and IATA DGR 6.3.5. Basic infection control procedures must also be followed, including adherence to universal precautions protocols. OSHA requires that blood and all body fluids be considered potentially infectious by those who handle them and that appropriate engineering and work practice controls be implemented while handling the specimen(s). 49CFR 172.701 states that any person handling specimens for transport must be trained and certified to handle medical specimens. The hospital, clinic or doctor’s office is considered the shipper of the package. Caution: Be sure to tighten lids on tubes and close bags securely. Packing and Transport of Specimens: To ensure optimum testing conditions for a specimen that is sent to BBPL Laboratories as well as the safety for all who package and transport the specimen, the client must determine two things: 1. Determine the type of specimen to be sent: Biological Substance, Category B (UN 3373) or Infection Substance, Category A (UN 2814). 2. Determine the temperature at which the specimen must be maintained during transit, using instruction for each individually listed test in the BBPL Directory of Services. Containers that may be accepted, but should be avoided: Glass tubes for refrigerated and ambient (room temperature) specimens Tubes from an automated aliquot system with a pop-top type of cap Syringes (where required). The syringe should be enclosed in a specimen transport bag and placed in a small cardboard box or plastic container with tight fitting lid to protect the plunger from accidental pushing. No needles should be attached. Client-specific containers BBPL shipment of specimens by ground or air transportation: Ground Transportation Category A and B specimens are regulated by the DOT. Dedicated private or contracted carrier is defined as a motor vehicle used exclusively to transport biological substances or biological products. While other medical or laboratory related materials may also be transported in this vehicle, its purpose is primarily for the transport of specimens. Air Transportation Charter, Commercial and Cargo aircraft are all used for the transportation of specimens to BBPL. IATA regulations must be followed for all of the listed air transport options. Regulations include procedures for Dry Ice, Category A versus Category B specimens, Markings/Labeling of shipments, and any documentation guidelines. Specimen Transportation 3-1 BBPL Directory of Services If your shipment contains the following, the specimens can be packaged and transported in the courier bag or routine flight box and be labeled as Category B, Biological Substance UN 3373: Materials that do not contain infectious substances or are unlikely to cause disease in humans Dried blood spots. Environmental samples. Substances transported for diagnostic or investigational purposes. Materials that contain an infectious substance that is not in a form generally capable of causing permanent disability or life threatening or fatal disease in otherwise healthy humans. S3 Category B shipment must be packed as follows: Leak proof primary receptacle not to exceed 500 mL containing the specimen. Adequate absorbent material in the secondary packaging. Leak proof secondary receptacle. A plastic leak proof bag is appropriate as secondary packaging. A biohazard warning label should be present on the secondary packaging. Primary and secondary receptacles must be capable of withstanding, without leakage, an internal pressure producing a pressure differential of not less than 95kpa (13.8psi) in the range or -40˚ to 130˚ F (-40˚ to 55˚C). Outer packaging (courier bag or flight box). The maximum quantity per outer packaging for category B specimens must not exceed 4 L. Packaging sample in appropriate temperature for specimen transport. If your shipment contains the following, it must be packaged separately as a Category A, Infectious Substance UN 2814 (Refer to list of Category A substances): Infectious substance in a form capable of causing permanent disability or life threatening or fatal disease in otherwise healthy humans. Likely to contain Category A. Characteristics of Category A. Carries health risk to carrier, personnel, still unknown. Package and transport per carrier’s specific instructions for Category A specimens. Complete the proper Shippers Declaration form. Dry Ice: Class 9 Miscellaneous Dangerous Label will be used only when dry ice is included in the shipment. The quantity of dry ice must be included on this label as ___kg. No more than 2.2 kg of dry ice is allowed per shipping container. When dry ice is used, care should be taken to allow enough space for carbon dioxide to escape as dry ice dissipates. 3-2 Specimen Transportation BBPL Directory of Services Examples of Infectious Substances Included in Category A in Any Form Unless Otherwise Indicated UN 2814 Infectious Substances Affecting Humans Bacillus anthracis (cultures only) Brucella abortus (cultures only) Brucella melitensis (cultures only) Brucella suis (cultures only) Burkholderia mallei - Pseudomonas mallei – Glanders (cultures only) Burkholderia pseudomallei – Pseudomonas pseudomallei (cultures only) Chlamydia psittaci - avian strains (cultures only) Clostridium botulinum (cultures only) Coccidioides immitis (cultures only) Coxiella burnetii (cultures only) Crimean-Congo hemorrhagic fever virus Dengue virus (cultures only) Eastern equine encephalitis virus (cultures only) Escherichia coli, verotoxigenic (cultures only) Ebola virus Flexal virus Francisella tularensis (cultures only) Guanarito virus Hantaan virus Hantaviruses causing hemorrhagic fever with renal syndrome Hendra virus Hepatitis B virus (cultures only Herpes B virus (cultures only) Human immunodeficiency virus (cultures only) Highly pathogenic avian influenza virus (cultures only) Japanese Encephalitis virus (cultures only) Junin virus Kyasanur Forest disease virus Lassa virus Machupo virus Marburg virus Monkeypox virus Mycobacterium tuberculosis (cultures only) Nipah virus Omsk hemorrhagic fever virus Poliovirus (cultures only) Rabies virus (cultures only) Rickettsia prowazekii (cultures only) Rickettsia rickettsii (cultures only) Rift Valley fever virus (cultures only) Russian spring-summer encephalitis virus (cultures only) Sabia virus Specimen Transportation Shigella dysenteriae type 1 (cultures only) Tick-borne encephalitis virus (cultures only) Variola virus Venezuelan equine encephalitis virus (cultures only) West Nile virus (cultures only) Yellow fever virus (cultures only) Yersinia pestis (cultures only) S3 UN 2900 Infectious Substances Affecting Animals African swine fever virus (cultures only) Avian paramyxovirus Type 1 – Velogenic Newcastle disease virus (cultures only) Classical swine fever virus (cultures only) Foot and mouth disease virus (cultures only) Lumpy skin disease virus (cultures only) Mycoplasma mycoides Contagious bovine pleuropneumonia (cultures only) Peste des petits ruminants virus (cultures only) Rinderpest virus (cultures only) Sheep-pox virus (cultures only) Goatpox virus (cultures only) Swine vesicular disease virus (cultures only) Vesicular stomatitis virus (cultures only) NOTE 1: The following list is not exhaustive. Infectious substances, including those containing new or emerging pathogens, which do not appear in the following list but which meet the same criteria must not be transported as a diagnostic specimen. In addition, if there is doubt as to whether or not a pathogen falls within this category it must not be transported as a diagnostic specimen. NOTE 2: In this table, the microorganisms indicated in italics are bacteria, mycoplasmas, rickettsiae, or fungi. NOTE 3: Cultures are the result of a process by which pathogens are intentionally propagated. This definition does not include human or animal patient samples. NOTE 4: If a health authority list is available that shows other pathogens regarded as Risk Group 4 this should also be taken into account and the substances should not be transported as diagnostic specimen. 3-3 BBPL Directory of Services Anatomic Pathology Specimens Introduction: Surgical, anatomical and consultative pathology services are available through pathologists associated with Boyce and Bynum Pathology Laboratories, P.C. A request for diagnosis based upon histopathology should be viewed as a request for consultation by another physician. Our Histopathology Department also offers: S4 Histochemical and immunochemical stains are available at an additional charge. Results will be telephoned to you by the consulting pathologist if requested, in order to expedite patient care. The patient’s previous tissue diagnoses are maintained in our computer files for correlation with the most recent biopsy specimen. Specimen Handling Routine: Label each container with patient’s name, physician’s name and source of the specimen. Complete a Histopathology Requisition and send with the specimen. The requisition must contain pertinent clinical information including patient’s age, sex, clinical impression and anatomical location of tissue. If submitting multiple specimens, use a separate container for each specimen and clearly identify specimens using A, B, C, D, etc., both on the specimen container and the requisition. Only one Histopathology Requisition is needed for multiple specimens, however, each specimen MUST be separately identified. Place each specimen in a tightly secured container with 10% neutral buffered formalin. Do not allow specimen to dry out. Do not send specimen for routine handling in saline. Use biohazard bags when transporting specimens. Do not crush the specimen with forceps, hemostats, or other instruments. Avoid using cautery. Do not force a large specimen into a small container – formalin must surround the specimen for proper fixation. Use of a container of adequate size with an opening large enough to remove the tissue is important (tissues do harden after being placed in the fixative). 4-1 Anatomic Pathology Specimens BBPL Directory of Services Cytology SpecimenV Introduction: It is essential for clinicians to refer their gynecological and non-gynecological specimens to a facility which provides the highest quality service. Accurate early detection of malignant, dysplastic, and infectious processes depend upon the expertise of the professionals who participate in this important aspect of patient care. Boyce and Bynum Pathology Laboratories, P.C. (BBPL) takes pride in performing Cytopathology services in accordance with the requirements of the College of American Pathologists and other appropriate regulatory agencies. Only the best cytotechnologists are employed and frequent continuing education and a comprehensive Quality Assurance Program insure the highest level of competency. S5 Comprehensive Approach to Cytopathology: To insure that you and your patient receive full benefit of a cytologic screening for the detection of neoplasia and pre-malignant changes, a comprehensive approach is utilized. The patient’s medical history and correlation of findings with other cytological and histological results on file are considered before reporting the final interpretation. We strive to provide prompt turnaround time and fax all findings of high-grade dysplasia or suspected malignancy. Specimen Collection – GYN: Boyce and Bynum processes and reports GYN samples submitted in SurePath collection vials, ThinPrep vials or conventional smears. Each slide and/or specimen container must be labeled with two (2) person specific identifiers. Person specific identifiers may include: requisition number, patient’s first and last name, medical record number, or date of birth. Glass slides need to be labeled on the frosted end in pencil. SurePath Pap Test Collection: Obtain an adequate sample using a broom-like detachable device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Separate the broom part of the device from the handle and place the broom into the collection vial. Cap the vial tightly and shake. Label the specimen with the two (2) person specific identifiers and submit with a completed Cytology test request form. ThinPrep Pap Test Collection: Obtain an adequate sample using a broom-like device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Rinse the collection device in the PreservCyt solution by rotating the device vigorously in the solution 10 times. Discard the collection device. Cap the vial tightly. Label the specimen with two (2) person specific identifiers and submit with a completed Cytology request form. Conventional, one smear One fixed smear using standard Pap collection methods. Spray slide immediately with cytology fixative. Do not allow to air dry before fixation. The frosted end of the slide and the slide holder must be labeled with two (2) person specific identifiers. Submit specimen with a completed Cytology test request form that includes clinical history. Cytopathology Reporting (Cervical/Vaginal): One critical aspect of quality assurance in cervical/vaginal cytology is communication of the cytopathologic finding to the referring physician in unambiguous terms that have clinical relevance. In order to accomplish this, the clinician must provide the lab with pertinent information when submitting a requisition with a cytology specimen. Essential Patient Information: 1. The patient’s name and date of birth 2. Date of specimen collection 3. Source of material submitted (cervical, endo-cervical, vaginal) 4. Submitting physician’s name Cytology Specimens 5-1 BBPL Directory of Services Essential Clinical Information: 1. Last menstrual period (LMP) 2. Hormonal status (e.g., post-menopausal, gravid) 3. Exogenous hormone therapy (including birth control pills, treatment for endocrine responsive malignancy, estrogen creams) 4. Histories of abnormal cytology, systemic chemotherapy, gynecologic surgery, laser surgery, cryosurgery, or electrocautery. 5. DES exposure 6. Patient’s risk status for cervical cancer 7. Other (non-GYN history of previous surgery, presence of other masses, etc.) S5 GYN Cytology Reports include: 1. 2. 3. 4. 5. 6. 7. 8. 5-2 Specimen Type • Indicates Liquid based specimen vs. conventional pap smear Case Number • In-house identification number Clinical History • Information provided by clinician • Information stored in Boyce and Bynum’s Laboratory Information System Statement of Adequacy • Satisfactory • Unsatisfactory No cells present Insufficient epithelial cells present for adequate cytological evaluation Extensive cellular degeneration or improper fixation Presence of lubricating material which compromises evaluation Cell preparation too thick for adequate cytological evaluation • Unacceptable – Reason for rejection No patient identification on slide or requisition Slides broken or beyond repair upon receipt Discrepancy between name of patient on specimen and name on requisition Interpretation – Bethesda 2001 System • Negative for Intraepithelial Lesion or Malignancy • Atypical Squamous Cells of Undetermined Significance • Atypical Squamous Cells, Cannot Rule out High Grade Lesion • Atypical Glandular Cells –Endometrial or Endocervical in origin. • Low Grade Squamous Intraepithelial Lesion – Mild Dysplasia/CIN I • High Grade Squamous Intraepithelial Lesion –Moderate Dysplasia/CIN II • High Grade Squamous Intraepithelial Lesion –Severe Dysplasia/CIN III • High Grade Squamous Intraepithelial Lesion –CIS/CIN III • Squamous Cell Carcinoma • Adenocarcinoma • Adenocarcinoma in situ Non-neoplastic findings: • Blood • Inflammation • Atrophy • Cellular changes consistent with herpes simplex virus • Trichomonas vaginalis • Fungal organisms consistent with Candida Comments • False Negative Notification • Reflex Ancillary Testing • BD FocalPoint Slide Profiler, if applicable Name of reviewing pathologist for cases with the following cellular changes • Reactive or reparative changes Cytology Specimens BBPL Directory of Services • • • • • Atypical squamous cells Dysplastic cellular changes Malignant and suspicious cellular changes Atypical glandular cell changes Endometrial cells out of phase or present in a patient over 40 Follow-up Program: Boyce and Bynum Pathology Laboratories, P.C. performs follow-up on cases of High Grade Squamous Intraepithelial Lesion or suspected malignancy. This is important in maintaining the standard of quality which Boyce and Bynum believes is vital to our cytology program. S5 Our follow-up program: • Provides us with an opportunity to correlate our cytologic diagnosis with biopsy findings. • Confirms that physicians have received a report and were notified that additional follow-up may be necessary. Cytology Specimens 5-3 BBPL Directory of Services Hemostasis/Thrombosis Specimens To produce valid results for hemostatis/thrombosis tests and factor assays, specimen integrity is crucial and must be maintained. All specimens sent for testing must be collected and shipped in the following manner: 1. Obtain venous blood by clean venipuncture at a site away from an intravenous line. Avoid slow flowing draws and/or traumatic venipunctures as either of these may result in an activated or clotted specimen. Do not use needles smaller than 23 gauge. Do not leave the tourniquet on for an extended length of time before drawing the sample. 2. Draw a pilot waste tube (non-additive or light blue top tube), as a recommended procedure, before drawing coagulation specimens in light blue-top vacuum tubes (3.2% buffered sodium citrate). Discard the pilot tube. Note: Reference intervals have been established using 3.2% buffered sodium citrate. 3. Fill light blue-top tubes as far as vacuum will allow and mix by gentle inversion (end over end) three to six times. Exact ratio of nine parts blood to one part anticoagulant must be maintained. Inadequate filling of the sample tube will alter this ratio and may lead to inaccurate results. The collection tube must be filled to at least 90% fill volume. S6 Patients who have hematocrit values above 55% should have the anticoagulant adjusted to maintain the 9:1 ratio. Use the following formula to determine the amount of anticoagulant to use: C = (0.00185) (V) (100-H) where: C = mLs of anticoagulant V = mL of whole blood H = Hematocrit in % When obtaining specimens from indwelling lines that may contain heparin, the line should be flushed with 5 mL of saline, and the first 5 mL of blood or 6 times the line volume (dead space volume of the catheter) should be drawn off and discarded before the coagulation tube is filled. For those samples collected from a normal saline lock (capped off venous port) twice the dead space volume of the catheter and extension set should be discarded. 4. Centrifuge the specimen at 1700 x g for 15 minutes (or at a speed and time required to consistently produce platelet-poor plasma—platelet count less than 10,000/µL) Grossly hemolyzed specimens will be rejected. 5. Immediately remove only the top two-thirds of the platelet-poor plasma from the specimen using a plastic transfer pipet (use of glass transfer pipets may result in activation and/or clotting of the plasma). Place the plasma in a properly labeled plastic transport tube and clearly mark the vial contents as Plasma. Glass vials will be rejected. 6. Immediately freeze the plasma in dry ice or a non-frost free freezer. Specimens may be stored at -20◦ C for up to two weeks or at -70◦ C for up to six months. Specimens must remain frozen during storage and shipment. A separate transport tube should be submitted for each assay requested. Specimens should be stored capped. Coagulation samples should not be stored at refrigerated temperatures (2-8◦ C) or on ice. Room temperature stabilities should be observed if a sample cannot be frozen immediately. 7. Acceptable time delay and short-term storage for coagulation tests: Prothrombin time (PT) specimens, uncentrifuged, centrifuged with plasma on top of cells, or centrifuged with plasma separated from cells, should be kept at room temperature for no longer than 24 hours from the time of collection. Activated Partial Thromboplastin Time (aPTT) specimens (not drawn to monitor heparin therapy) uncentrifuged with plasma on top of cells, or centrifuged with plasma separated from cells, should be kept at room temperature for no longer than four hours from the time of collection. Special coagulation tests have variable stabilities and should be stored in the manner as listed in the BBPL Directory of Services for the individual test. 6-1 Hemostasis/Thrombosis Specimens BBPL Directory of Services If testing cannot be performed within these times, platelet-poor plasma should be removed from the cells and frozen at -20◦C for up to two weeks or at -70◦C for up to six months. 8. All requests for coagulation assays should include a brief patient history and other pertinent clinical information (e.g., medications, blood products, etc). Note: Specimens containing heparin should not be used for coagulation studies. If possible, discontinue heparin therapy before the draw to avoid contamination. Heparin interferes with most clotting assays. S6 Hemostasis/Thrombosis Specimens 6-2 BBPL Directory of Services Microbiology Specimens Introduction: Quality results in microbiology depend on both the client and the laboratory. The successful isolation of potential pathogens from clinical specimens begins with specimen selection and collection, proper transportation container or media, and timely delivery to the laboratory. It is extremely important to refer to specimen collection and submission instructions to ensure that the most suitable or appropriate specimens for laboratory analysis are received. Note: Sensitivity testing will be performed on appropriate isolates at an additional charge. Specimen Collection: S7 1. 2. 3. 4. 5. Specimens should be taken when the patient is in the acute phase of the illness for best chance of bacterial recovery. Whenever possible, specimens should be obtained before antibiotics or other antimicrobial agents have been administered. Specimens should be collected from the area the physician considers infected, therefore, with specimens requiring swabbing, we recommend the collection be done by the physician rather than by the laboratory. Specimens for bacterial contamination should always be collected on sterile swabs or in sterile containers. DO NOT use swabs with wooden shafts or calcium alginate swabs. These inappropriate swabs will be rejected. The specimen must be accompanied by a test request form indicating the client number, the patient’s name, room number, patient identification number, type of culture requested, source (site) of specimen is required, dates and times of specimen collection and plating (if appropriate), physician’s name and any other useful information such as suspected organism or antibiotics requested if other than our routine. The name on the specimen must match the name on the requisition. The test(s) desired must be clearly marked on the test request form. Refer to the specimen, collection and submission requirements that follow for complete test information. Specimen Submission: The integrity of specimens must be maintained during transport. To accomplish this, various media and preservatives are provided. If the specimen is not properly submitted, results may not provide accurate clinical information. 1. 2. 3. 4. 5. 7-1 Sputum for bacteriology, mycobacteriology, or mycology should be transported in a sterile 50 mL centrifuge tube or other sterile, screw-cap container. Twist the cap securely closed after placing the specimen in the container. Refrigerate the specimen if transport to the laboratory will be delayed by one hour or more. Urine specimens for culture should be refrigerated if not plated within one hour of collection. For urine specimens which will not reach the Microbiology Laboratory within four hours of collection a Urine Culture Kit may be used. The specimen preserved in the Urine Culture Kit will remain valid for culture up to 72 hours while being sent to the laboratory. If urine is collected via a catheter, this must be noted on the specimen and the test request form. Urine from a catheter collection bag is not acceptable. Urine from an indwelling catheter must be obtained by sterile syringe from the catheter tubing immediately after the bladder has emptied. All specimens must be plated as soon as possible onto the appropriate media as indicated by plating protocol. Acid Fast specimens and fungus cultures will be plated at the Central Laboratory. Some clients prefer to plate specimens to appropriate media and send the inoculated media to the laboratory. All media and reagents should be brought to room temperature before inoculating. Culture plates, after inoculation, should be placed in the proper atmospheric condition and at the proper temperature until transporting to the Central Laboratory. This will require the availability of a 35°C, CO2 incubator. Most clients prefer to send the collected specimen to the laboratory to be inoculated to media. All media for plating is kept at the Central Laboratory and is supplied to the clients upon request. Store media under refrigeration and observe expiration dates. Thioglycollate Broth is kept at room temperature and should be boiled and allowed to cool before being used. It is acceptable to boil a quantity at the beginning of the day for use throughout the day. Only boil a tube once. If not used the same day, discard the tube. To transport specimens, use the double-sided plastic specimen bags, keeping the specimen or plates separated from the test request form. Microbiology Specimens BBPL Directory of Services Specimen Rejection: Specimens will be rejected if not collected in a sterile container or if more than four hours old unless proper holding procedures have been taken (such as refrigeration or transport media used). Dried culture swabs, syringes or other specimens with needles attached are unacceptable. Unlabeled specimens are unacceptable. Check under specific test requested for special handling requirements. Safety Precautions: When sending specimens through the courier system, be sure to tape or parafilm all plates securely and tape or parafilm the lids of all tubes to prevent leakage. After plating, place all swabs and contaminated specimens into the biohazard bags. S7 Stool Culture Guidelines: Containers for Stool Cultures: Raw Stool Rotavirus NOTE: Raw stool can be used for any tests done in Microbiology Department but there are different time limits for each test (some are less than 2 hours). Raw stool should always be refrigerated unless otherwise stated in specimen collection requirements. Some tests require frozen raw stool, please refer to individual test guidelines. Cary Blair Clostridium difficile (C diff) Toxin Stool Culture Yersinia Culture Campylobacter (Campy) Culture E. coli 0157:H7 Culture Giardia Antigen Cryptosporidium Antigen O & P Sets Formalin (pink top) O&P Giardia Antigen Cryptosporidium Antigen Microsporidium Stain Cryptosporidium, Cyclospora, Isospora stain PVA (blue top) O&P Fecal leukocytes Test Ordering Notes: Culture for C diff is not offered and is not included in a stool culture order. To order C diff, use order code 53810. If a stool culture and C diff are both needed, order 3260 stool culture and 53810 C diff. The Cryptosporidium Stain test is less sensitive than the Antigen test. Campylobacter species identification is included in the 3260 stool culture test. Stool culture detects Salmonella, Shigella, and Campylobacter species. Culture for other pathogens must be ordered separately. Microbiology Specimens 7-2 BBPL Directory of Services Molecular Diagnostics Specimens Introduction: This department offers state of the art clinical diagnostic flow cytometry, image analysis and nucleic acid probe technology. One or a combination of these techniques may be applied depending upon the diagnostic problem. Flow cytometric analysis is used to evaluate the hematopoietic system by utilizing monoclonal antibodies to identify and quantitate subpopulations of cells in peripheral blood, bone marrow and tissue such as lymph nodes and spleen. Lymphocyte Subset Analysis is requested to detect alteration in the immune system. A panel of T and B lymphocyte monoclonal antibodies is utilized to quantitate the various subpopulations of circulating lymphocytes that have characteristic membrane antigens. The relative and absolute numbers of T-helper, T-suppressor, Natural Killer, Activated T, Total T and Total B lymphocytes are the most common ones evaluated. The relationships among these subpopulations are frequently altered in patients with a variety of acquired or congenital immunodeficiency states including many types of viral infections, autoimmune diseases and in patients receiving immunosuppression therapy. S8 Cell Lineage and Immunophenotyping of hematologic malignancies is necessary for accurate classification of both acute and chronic leukemias and to establish monoclonality in suspected lymphoproliferative malignancies. A panel of monoclonal antibodies to myeloid and lymphoid surface markers is utilized to identify the cells in question and determine their degree of differentiation if possible. Cell Cycle Kinetics and DNA Ploidy analysis can be performed by both flow cytometry and image analysis. The presence of abnormal DNA content and/or increased proliferative activity have been shown to be unfavorable prognostic factors for many neoplasms. The most commonly referred malignancies for study are of the breast, colon, prostate, urinary bladder, lymph nodes, ovary, endometrium, kidney and thyroid. Image Analysis is performed using special stains or labeled monoclonal antibodies in order to quantitate cellular protein products, DNA or oncogenes. It offers the advantage of being able to visualize the tissue through a microscope so that the results are known to be derived only from the neoplastic cells in question. The most commonly performed tests currently are for estrogen receptor, progesterone receptor, and HER-2 neu. Gene Rearrangement studies using nucleic acid probes is an essential technique for establishing monoclonality of T cell lymphoproliferative processes and in some B cell processes that cannot be resolved by flow cytometry. Also, many leukemias and lymphomas are characterized by specific chromosomal translocations, deletions, or breakage that may be detected using gene rearrangement techniques. 8-1 Molecular Diagnostics Specimens BBPL Directory of Services Critical Value Policies Critical Values Critical results are classified into one of the following three categories: • • • Category I Life Threatening Results Category II Significantly Abnormal Results (non-life threatening) Category III Client-Specific Abnormal Results CATEGORY I Life threatening results are communicated to the client (office, treating physician, physician on call, or pathologist on call) as soon as confirmed by the testing laboratory. Category I critical results are communicated at any hour of the day or night to a physician so that appropriate medical treatment decisions can progress. CATEGORY I – CHEMISTRY CRITICAL VALUES TEST LOW HIGH Glucose < 40 mg/dL > 600 mg/dL Sodium < 120 mEq/L > 160 mEq/L Potassium < 2.7 mEq/L > 6.5 mEq/L Calcium < 6.0 mg/dL > 13.0 mg/dL Phosphorus < 1.0 mg/dL Magnesium < 0.7 mg/dL > 4.5 mg/dL Calcium, Ionized < 0.90 mmol/L > 1.50 mmol/L S9 CATEGORY I – HEMATOLOGY CRITICAL VALUES TEST LOW WBC < 2,000/mm3 Hemoglobin < 6.0 g/dL Platelet < 20,000/mm3 HIGH > 150,000/mm3 > 2,000,000/mm3 PT > 5.0 INR PTT > 90.0 seconds CATEGORY I – THERAPEUTIC DRUG CRITICAL VALUES TEST HIGH Carbamazepine > 20.0 µg/mL Digoxin > 4.0 ng/mL Gentamicin Trough > 2.5 µg/mL Peak > 12.0 µg/mL Lithium > 3.0 mEq/L Phenobarbital > 60.0 µg/mL Phenytoin > 40.0 µg/mL Phenytoin, Free > 3.0 µg/mL Theophylline > 40.0 µg/mL Valproic Acid > 175.0 µg/mL Vancomycin Trough > 30.0 µg/Ml Peak > 80.0 µg/mL Critical Value Policies 9-1 BBPL Directory of Services CATEGORY I – MICROBIOLOGY CRITICAL VALUES S9 TEST Gram Stain or Bacterial Culture CRITICAL RESULT Positive result from: Blood, CSF, Sterile Body Fluid, normally Sterile Tissue, Corneal Scrapings Bacterial Culture Presumptive identification from any site of: Bacillus anthracis, Brucella spp., Francisella tularensis, Vibrio cholera, Yersinia pestis, Burkholderia mallei or pseudo mallei India Ink Stain Positive from CSF Fungal Smear or Culture Identification of: dimorphic fungus, or Cryptococcus neoformans from any source Fungal Smear or Culture Positive result from: Blood, CSF, Sterile Body Fluid, normally Sterile Tissue, Corneal Scrapings Mycobacterial Smear or Culture Positive result from: Blood, CSF, Sterile Body Fluid, normally Sterile Tissue, Corneal Scrapings Stool Culture Presumptive identification of E.coli O157 in patients < 18 yr Shiga Toxin Positive in patients < 18 yr RSV Positive in patients < = 3 yr CATEGORY II Significantly Abnormal Results are non-life threatening, however may be abnormal enough in nature that the client (office or treating physician) should be alerted to the results, especially if the reported results are not yet available to the client. These results are communicated a) during normal business hours of the day the test result(s) are generated, or b) at the beginning of the next business day if the test result(s) are generated during non-business hours. CATEGORY II – CHEMISTRY ABNORMAL VALUES TEST HIGH Glucose 400 – 600 mg/dL Creatinine > 8.0 mg/dL BUN > 80 mg/dL CATEGORY II – HEMATOLOGY ABNORMAL VALUES TEST LOW HIGH WBC > 50,000/mm3 Hemoglobin 6.0-7.0 g/dL CATEGORY II – MICROBIOLOGY CRITICAL VALUES 9-2 TEST CRITICAL RESULT Stool Culture Presumptive growth of Salmonella, Shigella, or Yersinia Ova & Parasites- Fecal Presumptive or definitive E. histolytica Mycobacterial Smear or Culture Positive result from sites other than those designated for critical call Surgical Wound (surgical center/ hospital) Positive for Group A Strep Rotavirus Positive Bacterial Culture Presumptive Vancomycin Resistant Staph aureus Critical Value Policies BBPL Directory of Services CATEGORY III Client-Specific Abnormal results are non-life threatening, client specific, critical results. These results are communicated a) during normal business hours on the day the rest result(s) are generated or b) at the beginning of the next business day if the rest result(s) are generated during non-business hours. S9 Critical Value Policies 9-3 BBPL Directory of Services BBPL Test List 11-Deoxycortisol Quantitative Order code: 80000 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells and transport in a plastic transport tube refrigerated. Frozen serum is also acceptable. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 1.0 mL plasma, green (sodium heparin) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Grossly hemolyzed specimens. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 811600 CPT Code(s): 82634 Ref range: By report Reported: 2-5 days 17-Hydroxycorticosteroids, Urine Order code: 80020 Preferred specimen: 12.0 mL urine aliquot from a well-mixed 24-hour collection. Refrigerate 24-hour specimen during collection. Freeze urine aliquot after completion of 24-hour collection. Minimum specimen: 5.0 mL urine aliquot Notes: Record total volume and hours of collection on both the urine container and test request form. Other acceptable: Samples refrigerated with preservatives are acceptable. Mix well, add 1 g boric acid/100 mL urine, adjust pH (with boric acid) to 5.0-7.0 and freeze. Random specimens are acceptable, but are reported as mg/L and have no reference interval. Unacceptable: Samples previously preserved with NaOH. Transport temp: Frozen Method: Quantitative Colorimetry Unit code: 820950 CPT Code(s): 83491 Ref range: 17-Hydroxycorticosteroids per gram of creatinine: 2.0-6.5 mg/g crt S1 0 17-Hydroxycorticosteroids: 4.0-14.0 mg/d Reported: 3-7 days 17-Hydroxypregnenolone Quantitative, Serum or Plasma Order code: 82980 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection, aliquot 0.5 mL serum into two plastic transport tubes and freeze immediately. Minimum specimen: 0.25 mL serum or plasma per tube Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection, aliquot 0.5 mL plasma into two plastic transport tubes and freeze immediately. Unacceptable: Room temperature and refrigerated specimens. Transport temp: CRITICAL FROZEN Method: Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 820980 CPT Code(s): 84143 Ref range: By report Reported: 1-4 days 10-1 Test List BBPL Directory of Services 17-Hydroxyprogesterone Order code: 83251 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Include patient's age on the test request form. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectometry Unit code: 832551 CPT Code(s): 83498 Ref range: Adult Male: 27-199 ng/dL Adult Female: Follicular 15-70 ng/dL Luteal 35-290 ng/dL Reported: 3-5 days 17-Ketosteroids, Fractionated, Urine Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour collection. Refrigerate specimen during collection. Do not use preservatives. After completion of 24-hour collection, measure total volume, mix thoroughly, aliquot and transport urine frozen. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 2.6 mL urine aliquot Unacceptable: Specimens received at room temperature or refrigerated. Transport temp: Frozen Method: Gas Chromatography/Mass Spectrophotometry Unit code: 822750 Ref range: By report Reported: Within 10 days 17-Ketosteroids, Total, Urine Order code: 80060 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour urine collection. Refrigerate 24-hour specimen during collection. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 3.0 mL urine aliquot Notes: Adequate refrigeration is the most important aspect of specimen preservation. Transport temp: Refrigerated Method: Spectrophotometry (Zimmerman Reaction) Unit code: 822950 CPT Code(s): 83586 Ref range: By report Reported: 1-5 days 18-Hydroxycorticosterone Order code: 82952 Preferred specimen: 3.0 mL serum, red top or gel-barrier tube. Remove serum from cells within 1 hour of collection, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when mutiple tests are ordered. Minimum specimen: 1.0 mL serum or plasma Other acceptable: 3.0 mL plasma, lavender (EDTA) or green (sodium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze immediately. Transport temp: CRITICAL FROZEN Method: Quantitative Tandem Mass Spectrometry Unit code: 820952 CPT Code(s): 82542 Ref range: By report Reported: 5-12 days Test List 10-2 S1 0 BBPL Directory of Services 5'Nucleotidase Order code: 80070 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Allow specimen to clot completely at room temperature. Remove serum from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and refrigerate. Minimum specimen: 0.2 mL serum Unacceptable: Room temperature specimens. Avoid hemolysis. Transport temp: Refrigerated Method: Quantitative Enzymatic Unit code: 828800 CPT Code(s): 83915 Ref range: 0-15 U/L Reported: 1-2 days 5-a-Dihydrotestosterone Order code: 82160 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and freeze immediately. Specimen should be collected between 6-10 a.m. Minimum specimen: 0.6 mL serum Unacceptable: Hemolyzed or lipemic samples. Transport temp: Frozen Method: Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 811950 CPT Code(s): 82651 Ref range: Males: Premature: 100.0-530.0 pg/mL Full Term: 50.0-600.0 pg/mL 1 week-6 months: 120.0-850.0 pg/mL 7 months-9 years: 0.0-49.9 pg/mL 10-19 years: 0.0-533.0 pg/mL 20 years and older: 106.0-719.0 pg/mL Females: Premature: 20.0-130.0 pg/mL Full Term: 20.0-150.0 pg/mL 1 week-9 years: 0.0-49.9 pg/mL 10-19 years: 50.0-170.0 pg/mL 20 and older: 24.0-208.0 pg/mL Reported: 1-4 days S1 0 5-HIAA (5-Hydroxyindoleacetic Acid), Urine Order code: 80080 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Patient should abstain, if possible, from foods rich in serotonin (avocados, bananas, eggplant, pineapple, plums, tomatoes, walnuts), medications, over-the-counter drugs, and herbal remedies for at least 72 hours prior to and during collection of urine. Transport temp: Refrigerated Method: High Performance Liquid Chromatography Unit code: 819500 CPT Code(s): 83497 Ref range: 5-HIAA, Urine: 0.0-15.0 mg/d The HIAA-to-creatinine ratio will be reported whenever the urine collection is random or other than 24 hours, or the urine volume is less than 400 mL/24 hours. 5-HIAA, Urine: 0-14 mg/g crt Reported: 1-4 days 68 KD See: Heat Shock Protein 70 (68 kDa) 10-3 Test List BBPL Directory of Services A/G Ratio Order code: 1125 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Colorimetric, Calculation Unit code: 101715 CPT Code(s): 82040, 84155 Ref range: Protein: 6.0-8.5 g/dL Albumin: 3.0-5.5 g/dL Globulin: 1.5-3.5 g/dL A/G Ratio: Calculation Reported: Within 24 hours A1c See: Glycohemoglobin A1c with Estimated Average Glucose Abacavir Sensitivity See: HLA-B5701 Genotyping ABO Group and Rh Type Order code: 5030 Preferred specimen: One 7 mL lavender (EDTA) top tube. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 4.0 mL whole blood, lavender (EDTA) top tube Notes: Specimen should be labeled with patient name, date of birth, social security number and collection date. Transport temp: Refrigerated Method: Hemagglutination Unit code: 300200 CPT Code(s): 86900, 86901 S1 0 Ref range: By report Reported: 1-2 days Absolute Eosinophil Count See: Eosinophil Count, Absolute Acanthamoeba and Naegleria Culture Order code: 80048 Preferred specimen: Collect: Corneal scrapings or tissue, or vitreous fluid. Place corneal scrapings or tissue, or vitreous fluid in 2 mL of Page's amoeba saline. Transport specimen to the laboratory within 24 hours of collection at room temperature. Page's amoeba saline is available through BBPL Client Services. Record specimen source on test request form. Notes: For CSF refer to Acanthamoeba and Naegleria Culture and Stains, CSF (order code 80081). Unacceptable: Specimens in media or preservatives. Refrigerated or frozen specimens. Transport temp: CRITICAL at room temperature Method: Qualitative Culture/Microscopy Unit code: 800480 CPT Code(s): 87081 Ref range: Negative This culture will detect free-living amoeba such as Acanthamoeba species and Naegleria fowleri, but will NOT detect Balamuthia mandrillaris. Reported: 2-10 days Test List 10-4 BBPL Directory of Services Acanthamoeba and Naegleria Culture and Stains, CSF Order code: 80081 Preferred specimen: Collect CSF and transfer 1.0 mL CSF to a sterile transport tube. Transport to the laboratory within 24 hours of collection at room temperature. Minimum specimen: 0.5 mL CSF Unacceptable: Frozen or refrigerated specimens. Specimens submitted in transport media. Formalinized specimens. Leaking or non-sterile containers. Transport temp: CRITICAL at room temperature Method: Qualitative Culture/Microscopic Identification/Calcofluor Stain/Giemsa Stain Unit code: 800481 CPT Code(s): 87081, 87206, 87207 Ref range: Negative The stains will detect free-living amoeba such as Acanthamoeba species, Naegleria fowleri, and Balamuthia mandrillaris. The culture will detect free-living amoeba such as Acanthamoeba species and Naegleria fowleri, but will NOT detect Balamuthia mandrillaris. Reported: 2-10 days Accutane See: Isotretinoin, Quantitative ACE See: Angiotensin Converting Enzyme Acetaminophen Order code: 80110 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in gel-barrier tube. Minimum specimen: 0.5 mL serum Unacceptable: Plasma. Specimens collected in separator tubes, sodium fluoride/potassium oxalate, or sodium citrate anticoagulants. Transport temp: Refrigerated Method: Spectrophotometry Unit code: 800500 S1 0 CPT Code(s): 82003 Ref range: 10-30 µg/mL Critical values: Post four-hour ingestion: greater than 150 µg/mL Post 12-hour ingestion: greater than 40 µg/mL Reported: 1-2 days Acetone, Quantitative Order code: 80140 Preferred specimen: 0.5 mL serum, red top tube. Do not collect in gel-barrier tube. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 0.5 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Transport temp: Refrigerated Method: Quantitative Gas Chromatography Unit code: 800650 CPT Code(s): 82010 Ref range: Therapeutic range not well established - Assay detection limit 5 mg/dL Toxic: > 100 mg/dL Reported: 1-2 days 10-5 Test List BBPL Directory of Services Acetylcholine Receptor Antibody Panel Order code: 80749 Preferred specimen: 2.0 mL serum, gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 1.1 mL serum Notes: Test includes: Acetylcholine Receptor Binding Antibody Acetylcholine Receptor Blocking Antibody Acetylcholine Receptor Modulating Antibody Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Quantitative Radioimmunoassay/Semi-Quantitative Flow Cytometry Unit code: 800749 CPT Code(s): 83516 (x2), 83519 Ref range: Acetylcholine Receptor Binding Antibody: Negative: 0.0-0.4 nmol/L Positive: 0.5 nmol/L or greater Acetylcholine Receptor Blocking Antibody: Negative: 0-26% blocking Indeterminate: 27-41% blocking Positive: 42% or greater blocking Acetylcholine Receptor Modulating Antibody: Negative: 0-45% modulation Positive: 46% or greater modulation Reported: 2-7 days Acetylcholine Receptor Binding Antibody Order code: 80160 Preferred specimen: 0.5 mL serum, gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Notes: Initial diagnostic testing for myasthenia gravis. Unacceptable: Plasma. Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Quantitative Radioimmunoassay S1 0 Unit code: 800750 CPT Code(s): 83519 Ref range: Negative: 0.0-0.4 nmol/L Positive: 0.5 nmol/L or greater Reported: 2-3 days Acetylcholine Receptor Blocking Antibody Order code: 80170 Preferred specimen: 1.0 mL serum, gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Initial diagnostic testing for myasthenia gravis. Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Flow Cytometry Unit code: 800800 CPT Code(s): 83516 Ref range: Negative: 0-26% blocking Indeterminate: 27-41% blocking Positive: 42% or greater blocking Reported: 1-4 days Test List 10-6 BBPL Directory of Services Acetylcholine Receptor Modulating Antibody Order code: 80805 Preferred specimen: 0.5 mL serum, gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Notes: Assessment of clinical activity of and initial diagnostic testing for myasthenia gravis. Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Flow Cytometry Unit code: 800805 CPT Code(s): 83516 Ref range: Negative: 0-45% modulation Positive: 46% or greater modulation Reported: 2-7 days Acetylcholinesterase and Fetal Hemoglobin, Amniotic Fluid Order code: 80071 Preferred specimen: 2.0 mL amniotic fluid in a plastic transport tube. Minimum specimen: 1.0 mL amniotic fluid Notes: Please submit Patient History for Prenatal Cytogenetics form.The information on this form is required to perform prenatal cytogenetic testing. Complete the form and submit with the test request form and specimen. Include the Amniotic Fluid AFP and MoM results, if available. Transport temp: Refrigerated Method: Qualitative Gel Electrophoresis/Radial Immunodiffusion Unit code: 800701 CPT Code(s): 82013, 83033 Ref range: Acetylcholinesterase: Negative Fetal Hemoglobin: Negative Reported: 3-11 days Acetylcholinesterase, RBC See: Cholinesterase, RBC/Hgb Ratio S1 0 Acetylcholinesterase, Serum See: Cholinesterase, Serum Acid Fast Bacilli, Culture with Stain See: Culture, Acid Fast Bacilli, With Stain 10-7 Test List BBPL Directory of Services Acid Fast Bacilli, Stain Only Order code: 3360 Preferred specimen: See acceptable specimen types below. Indicate source on requisition. Sputum: 1. A first morning, deep cough specimen is recommended. 2. If a series of 3 specimens is requested, collect specimens on 3 consecutive days at 8-24 hour intervals (24 hours when possible). 3. Collect 5.0-10.0 mL specimen (Min 3.0 mL) in tightly sealed, sterile container. 4. Refrigerate. Urine: 1. A first morning specimen is recommended. Minimum of 10.0 mL. 2. Collect specimen in tightly sealed, sterile container. 3. Refrigerate. Body Fluids & Bronchial Washing: 1. Submit 5.0 mL specimen (Min 1.0 mL) in tightly sealed, sterile container. 2. Refrigerate. Spinal Fluid: 1. Submit 2.0-3.0 mL CSF (Min 1.0 mL) in a sterile screw-cap tube. Collect a separate specimen for chemistry or hematology testing if needed. 2. Submit at room temperature. Tissue: 1. Send tissue sample in tightly sealed, sterile container. 2. Cover the tissue with sterile saline to prevent drying. 3. Keep at room temperature. Wound Aspirates or Drainage: 1. Remove surface exudates by wiping with sterile saline or 70% alcohol. Collect fluid abscess material with a Luer tip syringe and/or remove material from the leading edge of the wound aseptically. For open lesions/abscesses, aspirate, if possible, material from under the margin of the lesion/abscess. 2. Note: Specimens submitted on swabs are not recommended. Please submit aspirate material, drainage fluid, or tissue for optimal quality of results. 3. Note: When submitting a syringe, remove the needle prior to submission and cap with a sterile syringe tip cap. 4. Refrigerate. Feces: 1. Submit a minimum of 1 g solid stool or 1.0-5.0 mL liquid stool in a clean leak-proof container. 2. Refrigerate. Bone Marrow & Blood: 1. Submit 5.0 mL blood (Min 1.0 mL) or 2.0 mL bone marrow (Min 0.5 mL) in either yellow (SPS) top tube or lysis-centrifugation tube. 2. Keep at room temperature. Notes: Submit specimen in tightly sealed, sterile container. Unacceptable: Specimens not stored at the proper temperature, blood or bone marrow not submitted in SPS or lysis-centrifugation tubes, or specimens greater than 72 hours old. Transport temp: Refrigerated: Sputum, Urine, Body Fluids, Bronchial Washing, Wound Aspirates or Drainage, Feces. Room temperature: Spinal Fluid (CSF), Tissue, Bone Marrow, Blood. Method: Fluorescent Stain Unit code: 400200 CPT Code(s): 87206 Reported: Within 24 hours Acid Hemolysin (Ham Test) Order code: 82940 Preferred specimen: Collect one 9 mL red top tube and one 4 mL lavender (EDTA) top tube. Transport 3.0 mL serum (removed from cells ASAP) and 4.0 mL whole blood (EDTA) to laboratory same day as collection. Send specimens to laboratory Sunday through Wednesday only. Indicate patient's blood type on test request form. Minimum specimen: 1.5 mL serum and 1.0 mL whole blood. Notes: This acid hemolysin (Ham) test is the preferred initial test for the rare genetic disorder, congenital dyserythropoietic anemia type II. Unacceptable: Specimens not received in laboratory same day as collected. Transport temp: Room temperature Method: Visual Identification of Hemolysis Unit code: 817150 CPT Code(s): 85475 Ref range: Negative Reported: 1-2 days Test List 10-8 S1 0 BBPL Directory of Services Acid Labile Subunit (ALS) Order code: 80089 Preferred specimen: 1.0 mL serum, gel-barrier tube. Remove serum from cells within 45 minutes of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL serum Transport temp: Frozen Method: Double Antibody Radioimmunoassay Unit code: 800890 CPT Code(s): 83519 Ref range: By report Reported: 3-17 days Acid Phosphatase, Prostatic See: Prostatic Acid Phosphatase Acid Phosphatase, Total Order code: 80190 Preferred specimen: 1.5 mL serum, red top tube. Allow specimen to clot completely at room temperature. Remove serum from cells, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL serum Unacceptable: Plasma. Non-frozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Enzymatic Unit code: 800900 CPT Code(s): 84060 Ref range: 0.0-4.3 U/L Reported: 1-2 days ACTH See: Adrenocorticotropic Hormone (ACTH) S1 0 Activated Protein C (APC) Resistance Profile Order code: 80175 Preferred specimen: 1.5 mL platelet-poor plasma, light blue (sodium citrate) top tube. Transfer platelet-poor plasma into a plastic transport tube and freeze immediately. Minimum specimen: 1.0 mL platelet-poor plasma. Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Serum, nonfrozen, or hemolyzed samples. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 801075 CPT Code(s): 85307 Ref range: 2.00 or greater Reported: 1-4 days Acute Lymphocytic Leukemia (ALL) Panel by FISH, Adult Order code: 80777 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL bone marrow or 2.0 mL whole blood Notes: Recommended FISH panel for adults with newly diagnosed ALL. Probes included: BCR/ABL, MLL, E2A, IGH, MYC. Please submit a Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) studies. Complete the form and submit with the test request form and specimen. Other acceptable: 10.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807770 CPT Code(s): 88271 (x5), 88275 (x5), 88291 Ref range: By report Reported: 3-10 days 10-9 Test List BBPL Directory of Services Acute Myeloid Leukemia Panel by FISH Order code: 80775 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL bone marrow or 2.0 mL whole blood Notes: Used to identify prognostically important translocations in newly diagnosed AML. Probes included: RPN1/MECOM (EVI1), EGR1, D7S486, RUNX1T1/RUNX1, KMT2A (MLL), and CBFB. The PML/RARA Translocation by Fish (order code 83133) is automatically added and performed along with the panel. However, due to the longer turnaround time required for the panel, the result of this probe is reported as soon as availalbe and is charged separately. Please submit a Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) studies. Complete the form and submit with the test request form and specimen. Other acceptable: 5.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807776 Ref range: Normal Reported: 3-10 days Acute Phase Reactant See: C-Reactive Protein Acylcarnitine Profile, Quant Order code: 81078 Preferred specimen: 0.5 mL plasma, green (sodium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple test are ordered. Minimum specimen: 0.1 mL plasma Notes: Results of acylcarnitine profiling should be interpreted in the context of clinical presentation as well as other laboratory tests, which may include urine organic acid analysis and molecular testing. Unacceptable: Non frozen specimens. Grossly hemolyzed specimens. Specimen type other than frozen plasma. Transport temp: Frozen Method: Flow Injection/Tandem Mass Spectrometry Unit code: 801078 S1 0 CPT Code(s): 82017 Ref range: By report Reported: 4-6 days ADAMTS13 Activity Order code: 80108 Preferred specimen: 1.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells and transfer to a plastic transport tube. Freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL platelet poor plasma. Unacceptable: Serum or EDTA plasma, nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Chromogenic Assay Unit code: 801080 CPT Code(s): 85397 Ref range: Greater than or equal to 67 percent. Reported: 1-4 days Adapin See: Doxepin & Metabolite Adenosine Deaminase, Pleural Fluid Order code: 80109 Preferred specimen: 0.3 mL pleural fluid. Centrifuge specimen at room temperature. Transfer fluid to a plastic transport tube and freeze. Specimen must remain frozen until received in testing laboratory. Minimum specimen: 0.1 mL pleural fluid Unacceptable: Whole blood. Bronchoalveolar lavage (BAL) specimens. Turbid specimens. Transport temp: Frozen Method: Quantitative Spectrophotometry Unit code: 801095 CPT Code(s): 84311 Ref range: 0.0 - 9.4 U/L Reported: 1-4 days Test List 10-10 BBPL Directory of Services Adenovirus 40-41 Antigens Order code: 81105 Preferred specimen: 5 g aliquot of stool in a clean unpreserved stool transport vial, frozen. Minimum specimen: 1 g stool Unacceptable: Specimens in formalin, other preservatives, or diapers. Transport temp: Frozen Method: Enzyme Immunoassay Unit code: 801105 CPT Code(s): 87301 Ref range: Negative Reported: 1-2 days Adenovirus Antibodies, IgG & IgM Order code: 80330 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Parallel testing is preferred and convalescent specimens must be received within 30 days of the acute specimens. Mark specimens plainly as "acute" or "convalescent". Minimum specimen: 0.05 mL serum Unacceptable: Plasma specimens. Lipemic, hemolyzed, icteric, turbid, bacterially contaminated, or heat-inactivated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 801100 CPT Code(s): 86603 Ref range: Adenovirus Antibody, IgG: 0.89 IV or less: Negative - No significant level of adenovirus IgG antibody detected. 0.90 - 1.10 IV: Equivocal - Questionable presence of adenovirus IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgG antibodies to adenovirus detected, which may suggest current or past infection. Adenovirus Antibody, IgM: 0.89 IV or less: Negative - No significant level of adenovirus IgM antibody detected. 0.90 - 1.10 IV: Equivocal - Questionable presence of adenovirus IgM antibody detected. Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgM antibodies to adenovirus detected, which may suggest current or recent infection. Reported: 1-6 days S1 0 Adenovirus DNA, Qualitative Real-Time PCR Order code: 39055 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction Unit code: 539055 CPT Code(s): 87798 Ref range: Negative Reported: 1-2 days ADH, Anti-Diuretic Hormone See: Arginine Vasopressin Adrenal 21-Hydroxylase Antibody Order code: 80094 Preferred specimen: 1.0 mL serum, red top tube. Minimum specimen: 0.2 mL serum Unacceptable: Hemolyzed or room temperature specimens. Transport temp: Refrigerated Method: Radioimmunoassay Unit code: 800946 CPT Code(s): 83497 Ref range: Less than or equal to 1.0 U/mL Addison's Disease: Greater than 1.0 U/mL Reported: 2-10 days Adrenaline & Noradrenaline See: Catecholamines, Fractionated 10-11 Test List BBPL Directory of Services Adrenocorticotropic Hormone (ACTH) Order code: 80200 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Collection tube must be siliconized glass or plastic. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Freeze immediately.ediately Minimum specimen: 0.5 mL plasma Unacceptable: Serum, tissue or urine. Heparinized plasma, grossly hemolyzed or lipemic specimens. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 800950 CPT Code(s): 82024 Ref range: Male and female - 1 week-9 years: 5-46 pg/mL Male and female - 10-18 years: 6-55 pg/mL Female - 19 years and older: 6-58 pg/mL Male - 19 years and older: 7-69 pg/mL Reported: 1-2 days Advil See: Ibuprofen AFB Culture With Stain See: Culture, Acid Fast Bacilli, With Stain AFB Stain Only See: Acid Fast Bacilli, Stain Only Afinitor See: Everolimus S1 0 AFP Serum See: Alpha Fetoprotein, Tumor Marker, Serum Maternal Serum Screen, Alpha Fetoprotein (Only) Maternal Serum Screen, Alpha Fetoprotein, hCG, & Estriol Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A AFP-L3% Preferred specimen: Alpha Fetoprotein, Total and L3 Percent Agglutinins, Cold See: Cold Agglutinins ALA See: Aminolevulinic Acid, Urine Alanine Aminotransferase (ALT) Order code: 1110 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Kinetic Unit code: 101810 CPT Code(s): 84460 Ref range: 0-45 U/L Reported: Within 24 hours Albumin, 24 Hour Urine See: Microalbumin, 24 Hour Urine Test List 10-12 BBPL Directory of Services Albumin, Fluid Order code: 1317 Preferred specimen: 1.0 mL body fluid in a plastic transport tube. Minimum specimen: 0.5 mL fluid Notes: Indicate source on test request form. Transport temp: Refrigerated Method: Colorimetric Unit code: 103173 CPT Code(s): 82042 Ref range: None established Reported: Within 24 hours Albumin, Serum Order code: 1080 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Colorimetric Unit code: 101710 CPT Code(s): 82040 Ref range: 3.0-5.5 g/dL Reported: Within 24 hours Albumin/Creatinine Ratio, Urine See: Microalbumin, Random Urine Alcohol, Ethyl, Blood Legal See: Ethanol, Blood, Qualitative Legal S1 0 Alcohol, Ethyl, Serum or Plasma See: Ethanol, Serum or Plasma Alcohol, Isopropyl See: Isopropanol (Includes Acetone) Alcohol, Methyl, Serum or Plasma See: Methanol, Serum or Plasma 10-13 Test List BBPL Directory of Services Alcohols Order code: 80162 Preferred specimen: 2.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a tightly-capped plastic transport tube to minimize alcohol loss. Minimum specimen: 0.3 mL serum or plasma Notes: For medical purposes only. Test includes: Acetone, Ethanol, Isopropanol, and Methanol. Other acceptable: 2.0 mL plasma, lavender (EDTA) or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells and transfer to a tightly-capped plastic transport tube. Sodium fluoride/potassium oxalate whole blood may be transported in the original container. Do not freeze whole blood. Transport temp: Refrigerated Method: Quantitative Gas Chromatography Unit code: 801602 CPT Code(s): 84600 Ref range: Isopropanol: Isopropanol: No therapeutic range - Test detection limit 5 mg/dL Toxic: > 50 mg/dL Ethanol: No therapeutic range - Test detection limit 10 mg/dL Therapy for Methanol: 100 - 200 mg/dL Ethyl alcohol levels greater than 100 mg/dL may be toxic. Acetone, Quantitative: No therapeutic range - Test detection limit 5 mg/dL Toxic: > 100 mg/dL Methanol: No therapeutic range - Test detection limit 5 mg/dL Toxic: Greater than 20 mg/dL Reported: 1-2 days Aldolase Order code: 80400 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells immediately after coagulation (within 30 minutes) and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma Notes: Not removing serum or plasma from cells results in aldolase levels 12% to 46% higher. Other acceptable: 0.5 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or light blue (sodium citrate) top tube. Remove plasma from cells immediately and transfer to a plastic transport tube. Unacceptable: Hemolyzed specimens. Transport temp: Refrigerated Method: Kinetic Unit code: 801800 CPT Code(s): 82085 Ref range: 1.2-7.6 units/L Reported: 1-3 days Aldosterone Order code: 80410 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum or plasma Notes: Remove serum or plasma from cells ASAP and transfer to a plastic transport tube. Record on test request form whether patient was supine or upright when blood was drawn. Prior to blood collection, it is recommended that patient be ambulatory for at least 30 minutes, on a normal sodium diet, taken off medications for a least 3 weeks, and no isotopes administered within 24 hours. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Gross hemolysis or lipemia, recently administered isotopes. Transport temp: Refrigerated Method: Radioimmunoassay Unit code: 801850 CPT Code(s): 82088 Ref range: By report Reported: 1-3 days Test List 10-14 S1 0 BBPL Directory of Services Aldosterone, Urine Order code: 80420 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour urine collection. Refrigerate 24-hour specimen during collection. Specimens without preservative must be aliquoted and frozen immediately after 24-hour collection is complete. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 0.5 mL urine aliquot Other acceptable: Preserved specimens with 1 g boric acid added per 100 mL of urine or with the pH adjusted to 2-4 with 6M HCl or 50 percent acetic acid. Refrigerate preserved specimens. Transport temp: Frozen Method: Quantitative Chemiluminescent Immunoassay Unit code: 801900 CPT Code(s): 82088 Ref range: Aldosterone, Urine: 1.2-28.1 µg/d Reported: 2-5 days Aldosterone:Renin Ratio Order code: 80855 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube and 1.0 mL plasma, lavender (EDTA) top tube. Remove serum from cells, transfer to a plastic transport tube, label tube as "Serum Aldosterone" Remove plasma from cells. transfer to a plastic transport tube, label tube as " Plasma Renin". Freeze both specimens immediately. Submit separate frozen specimens when multiple tests are ordered. Minimum specimen: 0.5 mL serum and 0.8 mL plasma Notes: Collect blood mid morning, after the patient has been upright (sitting, standing, or walking) for at least two hours and seated for 5 to 15 minutes. Patients should be instructed to maintain an unrestricted dietary salt intake prior to testing. Washout of all interfering antihypertensive medications may be considered in patients with mild hypertension, but is potentially problematic in others and perhaps unnecessary in that medications with minimal effect on the ARR can be used in their place. The patient should not take drugs that markedly affect the ARR for at least four weeks prior to blood collection. These drugs include: Spironolactone, eplerenone, amiloride, and triamterene Potassium-wasting diuretics Products derived from liquorice root (eg, confectionary licorice, chewing tobacco) Transport temp: Frozen Unit code: 801855 CPT Code(s): 82088, 84244 Ref range: 0-30 ng/dL per ng/mL/hour Reported: 1-3 days S1 0 ALK Rearrangement by FISH Order code: 80195 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block (0.2 cm³ piece of tissue) or 4 slides (4 micron thickness) from formalin-fixed paraffin block. Unacceptable: Paraffin-embedded tissue that has been decalcified. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 801955 CPT Code(s): 88367 (x2) Ref range: By report Reported: 2-10 days Alkaline Phosphatase Order code: 1085 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Colorimetric Unit code: 101720 CPT Code(s): 84075 Ref range: 30-140 U/L Reported: Within 24 hours 10-15 Test List BBPL Directory of Services Alkaline Phosphatase Isoenzymes Order code: 80430 Preferred specimen: 2.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and refrigerate or freeze immediately. Overnight fasting specimen is recommended. Minimum specimen: 1.0 mL serum or plasma. Notes: Test includes Total Alkaline Phosphatase and Bone, Liver, and Other Isoenzymes. When the Total Alkaline Phosphatase activity is increased, the Isoenzymes are useful in determining the source of the increased activity. Other acceptable: 2.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and refrigerate or freeze immediately. Unacceptable: Specimens collected in EDTA, sodium fluoride, or potassium oxalate. Grossly hemolyzed or lipemic specimens. Transport temp: Refrigerated or frozen Method: Heat Inactivation/Enzymatic Unit code: 801950 CPT Code(s): 84080 Ref range: By report Reported: 1-3 days ALL Panel by FISH, Adult See: Acute Lymphocytic Leukemia (ALL) Panel by FISH, Adult Allergen Profile, Basic Food Order code: 98018 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Notes: Includes: Immunoglobulin E (IgE) Baker's Yeast Barley Beef Chicken Chocolate Corn Egg White Milk Oat Orange Peanut Pork Potato Rye Soybean Tomato Wheat S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98018 CPT Code(s): 82785, 86003 (x17) Ref range: By report Reported: 1-3 days Test List 10-16 BBPL Directory of Services Allergen Profile, Central Missouri Inhalant Order code: 98050 Preferred specimen: 1.6 mL serum, red top tube or SST. Minimum specimen: 0.8 mL serum Notes: Includes: Immunoglobulin E (IgE) Alternaria tenuis American Cockroach Cat Dander Cladosporium herbarum Common Ragweed Dermatophagoides farinae Dermatophagoides pteronyssinus Dog Dander Elm Tree June Grass (Kentucky) Lamb's Quarter Oak Tree Perennial Rye Grass Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98050 CPT Code(s): 82785, 86003 (x13) Ref range: By report Reported: 1-3 days Allergen Profile, Common Adult Food Order code: 98020 Preferred specimen: 1.2 mL serum, red top tube or SST. Minimum specimen: 0.6 mL serum Notes: Includes: Cod Fish Corn Egg White Milk Peanut Shrimp Soybean Walnut Wheat S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98020 CPT Code(s): 82785, 86003 (x9) Ref range: By report Reported: 1-3 days 10-17 Test List BBPL Directory of Services Allergen Profile, Comprehensive Order code: 98005 Preferred specimen: 3.0 mL serum, red top tube or SST. Minimum specimen: 1.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Alternaria tenuis Aspergillus fumigatus Bermuda Grass Cat Dander Common Ragweed Dermatophagoides farinae Dermatophagoides pteronyssinus Dog Dander Elm Tree English Plantain Hormodendrum hordei House Dust-Greer House Dust-Stier Johnson Grass June Grass (Kentucky) Lamb's Quarter Maple Tree Meadow Fescue Mucor racemosus Oak Tree Orchard Grass Penicillium notatum Perennial Rye Grass Rough Marsh Elder Sweet Vernal Grass Timothy Grass Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98005 CPT Code(s): 82785, 86003 (x26) Ref range: By report Reported: 1-3 days S1 0 Test List 10-18 BBPL Directory of Services Allergen Profile, Comprehensive 2 Order code: 98006 Preferred specimen: 4.0 mL serum, red top tube or SST. Minimum specimen: 2.0 mL serum Notes: Includes: Immunoglobulin E (IgE) Alternaria tenuis American Cockroach Aspergillus fumigatus Bahia Grass Bermuda Grass Birch Tree Candida albicans Cat Dander Common Ragweed Cottonwood Tree Dermatophagoides farinae Dermatophagoides pteronyssinus Dog Dander Duck Feathers Elm Tree English Plantain Fusarium moniliforme Goose Feathers Helminthosporium halodes Hormodendrum hordei Johnson Grass June Grass (Kentucky) Lamb's Quarter Maple Tree Oak Tree Pecan Tree Penicillium notatum Phoma betae Red Cedar Tree Rhizopus nigricans Rough Marsh Elder Rough Pigweed Russian Thistle Sheep Sorrel Stemphylium botryosum White Ash Tree Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay S1 0 Unit code: 98006 CPT Code(s): 82785, 86003 (x36) Ref range: By report Reported: 1-3 days 10-19 Test List BBPL Directory of Services Allergen Profile, Comprehensive 3 Order code: 98007 Preferred specimen: 3.5 mL serum, red top tube or SST. Minimum specimen: 1.7 mL serum Notes: Includes: Immunoglobulin E (IgE) Alternaria tenuis Bermuda Grass Birch Tree Candida albicans Cat Dander Cladosporium herbarum Cocklebur Cottonwood Tree Dermatophagoides farinae Dog Dander Elm Tree Giant Ragweed Helminthosporium halodes House Dust (Greer) June Grass (Kentucky) Lamb's Quarter Maple Tree Mountain Cedar Tree Orchard Grass Penicillium notatum Perennial Rye Grass Redtop Grass Rhizopus nigricans Rough Marsh Elder Rough Pigweed Sheep Sorrel Sycamore Tree Timothy Grass White Hickory Tree Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98007 CPT Code(s): 82785, 86003 (x29) Ref range: By report Reported: 1-3 days Allergen Profile, Comprehensive Food Order code: 98019 Preferred specimen: 2.5 mL serum, red top tube or SST. Minimum specimen: 1.3 mL serum Notes: Includes: Immunoglobulin E (IgE) Baker's Yeast Barley Beef Chicken Chocolate Cod Corn Egg White Lettuce Malt Milk Oat Orange Peanut Pork Potato Rye Shrimp Soybean Strawberry Tomato Walnut Wheat Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98019 CPT Code(s): 82785, 86003 (x23) Ref range: By report Reported: 1-3 days Test List 10-20 S1 0 BBPL Directory of Services Allergen Profile, Grasses Order code: 98045 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Bermuda Grass Johnson Grass June Grass (Kentucky) Orchard Grass Perennial Rye Grass Timothy Grass Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98045 CPT Code(s): 82785, 86003 (x6) Ref range: By report Reported: 1-3 days Allergen Profile, Midwest Region Order code: 98081 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Notes: Includes: Immunoglobulin E (IgE) Alternaria tenuis Bermuda Grass Birch Tree Cat Dander Common Ragweed Dermatophagoides farinae Dermatophagoides pteronyssinus Dog Dander Elm Tree Johnson Grass June Grass (Kentucky) Maple Tree Oak Tree Orchard Grass Rough Marsh Elder Walnut Tree S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98081 CPT Code(s): 82785, 86003 (x16) Ref range: By report Reported: 1-3 days Allergen Profile, Molds Order code: 98065 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Alternaria tenuis Aspergillus fumigatus Hormodendrum hordei Mucor racemosus Penicillium notatum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98065 CPT Code(s): 82785, 86003 (x5) Ref range: By report Reported: 1-3 days 10-21 Test List BBPL Directory of Services Allergen Profile, North Central Order code: 98082 Preferred specimen: 1.6 mL serum, red top tube or SST. Minimum specimen: 0.8 mL serum Notes: Includes: Immunogobulin E (IgE) Alternaria tenuis Cat Dander Common Ragweed Dermatophagoides farinae Dermatophagoides pteronyssinus Dog Dander Elm Tree Hormodendrum hordei House Dust-Stier June Grass (Kentucky) Lamb's Quarter Oak Tree Orchard Grass Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98082 CPT Code(s): 82785, 86003 (x13) Ref range: By report Reported: 1-3 days Allergen Profile, Nut Mix Order code: 98030 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Almond Coconut Peanut Pecan Sesame Seed Unacceptable: Plasma, severely hemolyzed or lipemic specimens. S1 0 Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98030 CPT Code(s): 82785, 86003 (x5) Ref range: By report Reported: 1-3 days Allergen Profile, Pediatric Order code: 98070 Preferred specimen: 1.2 mL serum, red top tube or SST. Minimum specimen: 0.6 mL serum Notes: Includes: Immunoglobulin E (IgE) Alternaria tenuis Cat Dander Dermatophagoides farinae Dermatophagoides pteronyssinus Dog Dander Egg White Hormodendrum hordei House Dust-Stier Milk Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98070 CPT Code(s): 82785, 86003 (x9) Ref range: By report Reported: 1-3 days Test List 10-22 BBPL Directory of Services Allergen Profile, Pediatric 2 Order code: 98072 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Notes: Includes: Immunoglobulin E (IgE) Baker's Yeast Cat Dander Common Ragweed Corn Dermatophagoides pteronyssinus Dog Dander Egg White Hormodendrum hordei June Grass (Kentucky) Maple Tree Milk Orange Peanut Soybean Wheat Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98072 CPT Code(s): 82785, 86003 (x15) Ref range: By report Reported: 1-3 days Allergen Profile, Pediatric Food Order code: 98071 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Egg White Milk Oat Peanut Soybean Wheat S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98071 CPT Code(s): 82785, 86003 (x6) Ref range: By report Reported: 1-3 days Allergen Profile, Trees Order code: 98090 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Birch Tree Elm Tree Maple Tree Oak Tree Walnut Tree Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98090 CPT Code(s): 82785, 86003 (x5) Ref range: By report Reported: 1-3 days 10-23 Test List BBPL Directory of Services Allergen Profile, Weeds Order code: 98095 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Common Ragweed English Plantain Lamb's Quarter Rough Marsh Elder Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98095 CPT Code(s): 82785, 86003 (x4) Ref range: By report Reported: 1-3 days Allergen, Almond Order code: 98101 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98101 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Alpha-Gal (galactose-alpha-1,3-galactose) IgE Order code: 83943 Preferred specimen: 1.0 mL serum, plain red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Transport at room temperature. Also acceptable refrigerated or frozen. Minimum specimen: 0.5 mL serum Unacceptable: Hemolyzed, icteric, or lipemic specimens. Transport temp: Room temperature Method: Immunoassay Unit code: 833943 CPT Code(s): 86003 Ref range: By report Reported: 3-5 days Allergen, Alternaria tenuis Order code: 98106 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98106 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, American Cockroach Order code: 98111 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98111 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Test List 10-24 S1 0 BBPL Directory of Services Allergen, Anaheim Pepper See: Allergen, Pepper C. annuum Allergen, Apple Order code: 94776 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833934 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Aspergillus fumigatus Order code: 98120 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98120 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days S1 0 Allergen, Avocado Order code: 83964 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833964 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Bahia Grass Order code: 98130 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98130 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-25 Test List BBPL Directory of Services Allergen, Bakers Yeast Order code: 98131 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98131 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Banana Order code: 83969 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833969 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Barley Order code: 98135 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98135 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Basil IgE Order code: 83974 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833974 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-26 BBPL Directory of Services Allergen, Beef Order code: 98145 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98145 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Bell Pepper/Paprika See: Allergen, Pepper C. annuum Allergen, Bermuda Grass Order code: 98150 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98150 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Birch Tree Order code: 98158 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98158 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Black Pepper IgE Order code: 83994 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833994 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-27 Test List BBPL Directory of Services Allergen, Blackberry IgE Order code: 83990 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833999 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Blue Mussel Order code: 84008 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834008 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Blueberry Order code: 83409 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834009 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Brazil Nut Order code: 83414 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834014 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-28 S1 0 BBPL Directory of Services Allergen, Broccoli Order code: 94778 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833936 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Buckwheat IgE (Fagopyrum esculentum) Order code: 84019 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834019 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days S1 0 Allergen, Butter Bean See: Allergen, Lima Bean Allergen, Cabbage Order code: 84024 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834024 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Candida albicans Order code: 98171 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98171 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-29 Test List BBPL Directory of Services Allergen, Cantaloupe See: Allergen, Honeydew/Cantaloupe Allergen, Capsicum annuum See: Allergen, Pepper C. annuum Allergen, Carrot Order code: 94780 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833938 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Casein Order code: 94779 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay S1 0 Unit code: 833937 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Cashew Order code: 83359 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833859 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-30 BBPL Directory of Services Allergen, Cat Dander Order code: 98181 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98181 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Catfish IgE Order code: 84044 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834044 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Cayenne Pepper See: Allergen, Pepper C. annuum S1 0 Allergen, Celery Order code: 84049 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834049 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Cheddar Cheese Order code: 84054 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834054 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-31 Test List BBPL Directory of Services Allergen, Cherry IgE Order code: 83405 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834059 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Chestnut Order code: 84064 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834064 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Chicken Meat Order code: 98187 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98187 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Chili Pepper See: Allergen, Pepper C frutescens Allergen, Chocolate Order code: 98192 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98192 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Test List 10-32 S1 0 BBPL Directory of Services Allergen, Cinnamon Order code: 84074 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834074 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Cladosporium herbarum Order code: 98194 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98194 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Clam Order code: 84079 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. S1 0 Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834079 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Clove IgE Order code: 84081 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834081 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-33 Test List BBPL Directory of Services Allergen, Cocklebur Order code: 98197 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98197 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Coconut Order code: 98198 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98198 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Cod Order code: 98199 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98199 S1 0 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Coffee Order code: 84089 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834089 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Common Ragweed Order code: 98202 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98202 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Test List 10-34 BBPL Directory of Services Allergen, Corn Order code: 98208 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98208 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Corn Pollen Order code: 83368 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833868 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Cottonwood Tree Order code: 98213 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98213 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Cow Hair & Dander Order code: 83870 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833870 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-35 Test List BBPL Directory of Services Allergen, Crab Order code: 83371 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833871 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Cranberry IgE Order code: 84099 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834099 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days S1 0 Allergen, Cubanelle Pepper See: Allergen, Pepper C. annuum Allergen, Cucumber IgE Order code: 83419 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834109 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Cumin Seed IgE Order code: 84114 Preferred specimen: 0.5 mL serum, red top tube or SST. Plus 0.25 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum, plus 0.1 mL for each additional allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative Conventional RAST Unit code: 834114 CPT Code(s): 86003 Ref range: By report Reported: 3-6 days Test List 10-36 BBPL Directory of Services Allergen, Dermatophagoides farinae Order code: 98223 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98223 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Dermatophagoides pteronyssinus Order code: 98225 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98225 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Dog Dander Order code: 98233 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98233 S1 0 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Egg White Order code: 98243 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98243 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Egg Yolk Order code: 83375 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833875 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-37 Test List BBPL Directory of Services Allergen, Egg, Whole Order code: 83933 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833933 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Elm Tree Order code: 98250 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98250 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, English Plantain Order code: 98253 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98253 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Feathers, Duck Order code: 98263 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98263 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Feathers, Goose Order code: 98264 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98264 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Test List 10-38 BBPL Directory of Services Allergen, Fish Profile IgE Order code: 94912 Preferred specimen: 0.8 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum, plus 0.04 mL for each allergen ordered. Notes: Allergens included: Codfish, Halibut, Mackerel, Salmon, Trout, and Tuna Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 94912 CPT Code(s): 86003 (x6) Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Fusarium moniliforme Order code: 98275 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98275 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Garlic Order code: 84149 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. S1 0 Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834149 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Giant Ragweed Order code: 98284 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98284 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-39 Test List BBPL Directory of Services Allergen, Gluten Order code: 94782 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833940 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Grape Order code: 84174 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834174 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Green Bean (String) IgE Order code: 84184 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834184 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Halibut Order code: 84199 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834199 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-40 S1 0 BBPL Directory of Services Allergen, Hazelnut (Filbert) Order code: 83424 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834204 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Helminthosporium halodes Order code: 98304 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98304 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Honey IgE Order code: 84214 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. S1 0 Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834214 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Honeybee Venom IgE Order code: 83384 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833854 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-41 Test List BBPL Directory of Services Allergen, Honeydew/Cantaloupe Order code: 84219 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834219 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Hops Order code: 84220 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834220 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Hormodendrum hordei Order code: 98308 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98308 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Horse Hair/Dander Order code: 83381 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833881 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-42 S1 0 BBPL Directory of Services Allergen, House Dust Greer Order code: 98314 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98314 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, House Dust Stier Order code: 98315 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98315 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Jalapeno Pepper See: Allergen, Pepper C. annuum Allergen, Johnson Grass Order code: 98344 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98344 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, June Grass (Kentucky) Order code: 98347 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98347 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-43 Test List BBPL Directory of Services Allergen, Kiwi Order code: 83429 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834229 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Kochia/Firebush Order code: 83378 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833878 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Lambs Quarter Order code: 98372 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98372 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Lemon Order code: 94783 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833941 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-44 S1 0 BBPL Directory of Services Allergen, Lettuce Order code: 98378 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98378 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Lima Bean/White Bean Order code: 84244 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834244 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Lobster Order code: 83425 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. S1 0 Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834254 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Macadamia Nut IgE Order code: 84259 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834259 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-45 Test List BBPL Directory of Services Allergen, Mackerel Order code: 84264 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834264 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Malt Order code: 98391 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98391 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Mango Order code: 84269 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834269 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Maple Tree Order code: 98394 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98394 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Test List 10-46 S1 0 BBPL Directory of Services Allergen, Meadow Fescue Order code: 98399 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98399 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Milk Order code: 98402 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98402 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Mountain Cedar Tree Order code: 98403 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98403 S1 0 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Mucor racemosus Order code: 98405 Preferred specimen: 0.25 mL serum, red top tube or SST Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98405 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Mugwort Order code: 83898 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833898 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-47 Test List BBPL Directory of Services Allergen, Mushroom Order code: 84279 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834279 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Mustard Order code: 84284 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834284 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Navy Bean IgE Order code: 84289 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834289 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Nutmeg IgE Order code: 84294 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834294 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-48 S1 0 BBPL Directory of Services Allergen, Oak Tree Order code: 98431 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98431 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Oat Order code: 98434 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98434 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Occupational, Latex IgE Order code: 83932 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay S1 0 Unit code: 833932 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Onion Order code: 84304 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834304 CPT Code(s): 86003 Reported: 1-2 days Allergen, Orange Order code: 98441 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98441 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-49 Test List BBPL Directory of Services Allergen, Orchard Grass Order code: 98444 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98444 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Oregano IgE Order code: 84309 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834309 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Oyster Order code: 84324 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834324 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Paper Wasp Order code: 83904 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833904 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-50 S1 0 BBPL Directory of Services Allergen, Parsley IgE Order code: 83434 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834334 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Pea Order code: 84339 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834339 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days S1 0 Allergen, Peach Order code: 83444 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834344 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Peanut Order code: 98456 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98456 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-51 Test List BBPL Directory of Services Allergen, Pecan Nut Order code: 98457 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98457 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Pecan Tree Order code: 98458 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98458 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Penicillin G (Major) Order code: 84655 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay S1 0 Unit code: 830000 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Penicillin V (Minor) Order code: 83001 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 830001 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-52 BBPL Directory of Services Allergen, Penicillium notatum Order code: 98459 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98459 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Pepper C. annuum IgE Order code: 94777 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833935 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Pepper C. frutescens IgE Order code: 83459 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. S1 0 Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834359 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Perennial Rye Grass Order code: 98462 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98462 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-53 Test List BBPL Directory of Services Allergen, Phoma betae Order code: 98463 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98463 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Pine (Pinon) Nut Order code: 84369 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834369 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Pineapple Order code: 83437 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834374 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Pinto Bean See: Allergen, Navy Bean IgE Allergen, Pistachio Order code: 83479 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834379 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-54 S1 0 BBPL Directory of Services Allergen, Plum Order code: 84384 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834384 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Poblano Pepper See: Allergen, Pepper C. annuum Allergen, Pork Order code: 98469 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98469 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days S1 0 Allergen, Potato Order code: 98474 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98474 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Pumpkin Seed IgE Order code: 84394 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834394 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-55 Test List BBPL Directory of Services Allergen, Raspberry IgE Order code: 83439 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834399 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Red Cedar Tree Order code: 98512 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98512 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Red Dye IgE Order code: 83404 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834404 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Redtop Grass Order code: 98513 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98513 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Test List 10-56 S1 0 BBPL Directory of Services Allergen, Rhizopus nigricans Order code: 98515 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98515 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Rice Order code: 84414 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834414 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Rough Marsh Elder Order code: 98518 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98518 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Rough Pigweed Order code: 98519 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98519 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Russian Thistle Order code: 98522 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98522 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-57 Test List BBPL Directory of Services Allergen, Rye Order code: 98526 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98526 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Salmon Order code: 83329 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834429 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Scallop Order code: 83391 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833913 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Seafood Profile IgE Order code: 94924 Preferred specimen: 0.65 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.4 mL serum, plus 0.04 mL for each allergen ordered. Notes: Allergens included: Codfish/Whitefish, Crab, Lobster, Shrimp, and Tuna. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 94924 CPT Code(s): 86003 (x5) Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Serrano Pepper See: Allergen, Pepper C. annuum Test List 10-58 S1 0 BBPL Directory of Services Allergen, Sesame Seed Order code: 98535 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98535 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Shallot See: Allergen, Onion Allergen, Sheep Epithelium Order code: 83914 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833914 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days S1 0 Allergen, Sheep Sorrel Order code: 98538 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98538 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Shell Fish Profile IgE Order code: 94926 Preferred specimen: 0.85 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.48 mL serum, plus 0.04 mL for each allergen ordered. Notes: Allergens included: Blue Mussel, Clam, Crab, Lobster, Oyster, Scallop, and Shrimp. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 94926 CPT Code(s): 86003 (x7) Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-59 Test List BBPL Directory of Services Allergen, Shrimp Order code: 98542 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98542 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Soybean Order code: 98555 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98555 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Spinach Order code: 84444 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay S1 0 Unit code: 834444 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Squid IgE Order code: 84449 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834449 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-60 BBPL Directory of Services Allergen, Stemphylium botryosum Order code: 98560 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98560 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Strawberry Order code: 98563 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98563 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Summer Squash IgE Order code: 84464 Preferred specimen: 0.5 mL serum, plain red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Transport refrigerated. Room temperature and frozen specimens are also acceptable. Minimum specimen: 0.5 mL serum Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative Conventional Rast S1 0 Unit code: 834464 CPT Code(s): 86003 Ref range: By report Reported: 3-6 days Allergen, Sunflower Seed IgE Order code: 83469 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834469 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-61 Test List BBPL Directory of Services Allergen, Sweet Potato IgE Order code: 83474 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834474 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Sweet Vernal Grass Order code: 98571 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98571 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Sycamore Tree Order code: 98574 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98574 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Tea Order code: 83484 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834484 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-62 BBPL Directory of Services Allergen, Thyme IgE Order code: 83489 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834489 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Tilapia IgE Order code: 84494 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834494 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days S1 0 Allergen, Timothy Grass Order code: 98585 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98585 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Tomato Order code: 98592 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98592 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days 10-63 Test List BBPL Directory of Services Allergen, Trout Order code: 83449 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834499 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Tuna Order code: 83450 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834504 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Turkey Order code: 84509 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834509 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Walnut Order code: 98624 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98624 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Test List 10-64 S1 0 BBPL Directory of Services Allergen, Walnut Tree Order code: 98625 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98625 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Watermelon IgE Order code: 83452 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834524 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Wheat Order code: 98632 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum S1 0 Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98632 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, Whey IgE Order code: 84529 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 834529 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days 10-65 Test List BBPL Directory of Services Allergen, White Ash Tree Order code: 98634 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98634 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, White Hickory Tree Order code: 98636 Preferred specimen: 0.25 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 98636 CPT Code(s): 86003 Ref range: By report Reported: 1-3 days Allergen, White-Faced Hornet Order code: 83925 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay S1 0 Unit code: 833925 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergen, Yellow Jacket Venom Order code: 83928 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833928 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Test List 10-66 BBPL Directory of Services Allergen, Yellow-Faced Hornet Order code: 83927 Preferred specimen: 0.25 mL serum, SST. Plus 0.1 mL serum for each additional allergen. Multiple specimen tubes should be avoided. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum, plus 0.04 mL for each allergen ordered. Unacceptable: Hemolyzed, icteric or lipemic specimens. Transport temp: Refrigerated Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay Unit code: 833927 CPT Code(s): 86003 Ref range: Less than 0.10 kU/L: No significant level detected 0.10-0.34 kU/L: Clinical relevance undetermined 0.35-0.70 kU/L: Low 0.71-3.50 kU/L: Moderate 3.51-17.50 kU/L: High 17.51 kU/L or greater: Very High Reported: 1-2 days Allergens, Stinging Insect Group Order code: 83583 Preferred specimen: 0.70 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Honeybee Venom Paper Wasp White-Faced Hornet Yellow-Faced Hornet Yellow Jacket Venom Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: ImmunoCAP® Unit code: 94980 CPT Code(s): 86003 (x5) Ref range: By report Reported: 1-3 days S1 0 Allergens, Stinging Insect Group with IgE Order code: 83584 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Immunoglobulin E (IgE) Honeybee Venom Paper Wasp White-Faced Hornet Yellow-Faced Hornet Yellow Jacket Venom Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: ImmunoCAP® Unit code: 94981 CPT Code(s): 82785, 86003 (x5) Ref range: By report Reported: 1-3 days Almarytm See: Flecainide 10-67 Test List BBPL Directory of Services Alpha Fetoprotein (AFP Amniotic Fluid) with Reflex to Acetylcholinesterase and Fetal Hemoglobin Order code: 80342 Preferred specimen: 2.5 mL amniotic fluid in plastic transport tube. Minimum specimen: 1.5 mL amniotic fluid Notes: Include gestational age at time of collection or estimated due date on the test request form. Please submit Patient History for Prenatal Cytogenetics form. The information on this form is required to perform prenatal cytogenetic testing. Complete the form and submit with the test request form and specimen. If the AFP (amniotic fluid) is elevated, then Acetylcholinesterase and Fetal Hemoglobin will be added at an additional charge. Acetylcholinesterase testing requires an additional 3-11 days to be reported. Unacceptable: Specimens contaminated with fetal blood. Transport temp: Room temperature Method: Chemiluminescent Immunoassay/Electrophoresis Unit code: 801150 CPT Code(s): 82106 Ref range: By report Reported: 3-4 days Alpha Fetoprotein, Maternal Serum See: Maternal Serum, (AFP) Maternal Serum, hCG & Estriol Maternal Serum, hCG, Estriol & Inhibin Alpha Fetoprotein, Total and L3 Percent Order code: 81451 Preferred specimen: 1.0 mL serum, SST. Allow specimen to clot completely at room temperature. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: The µTASWako method is used. Results obtained with different assay methods or kits cannot be used interchangeably. Unacceptable: Plasma Transport temp: Frozen Method: Quantitative Liquid Chromatography/Immunoassay Unit code: 801451 CPT Code(s): 82107 S1 0 Ref range: By report Reported: 1-8 days Alpha Fetoprotein, Tumor Marker, Serum Order code: 1230 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111008 CPT Code(s): 82105 Ref range: 0-8.0 ng/mL Reported: Within 24 hours Alpha Subunit of Pituitary Glycoprotein Hormones Order code: 80202 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Hemolyzed or lipemic specimens. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 802020 CPT Code(s): 83520 Ref range: Adult Male: 0.0-0.7 ng/mL Adult Female: 0.0-1.4 ng/mL Reported: 1-8 days Test List 10-68 BBPL Directory of Services Alpha Thalassemia (HBA1 & HBA2) 7 Deletions Order code: 82015 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Notes: Please submit completed Patient History for Hemoglobinopathy/Thalassemia Testing form with test request form and specimen. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Gel Electrophoresis Unit code: 802015 CPT Code(s): 81257 Ref range: By report Reported: 7-10 days Alpha-1-Antitrypsin Order code: 80090 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum or plasma Notes: Remove serum or plasma from cells ASAP. Overnight fasting is preferred. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Chylous specimens. Transport temp: Refrigerated Method: Immunologic Unit code: 800050 CPT Code(s): 82103 Ref range: 90-200 mg/dL Reported: 2-3 days Alpha-1-Antitrypsin Phenotype Order code: 80100 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.7 mL serum Notes: Overnight fasting is preferred. Unacceptable: Hemolysis, specimens at room temperature. S1 0 Transport temp: Refrigerated Method: Isoelectric Focusing/Immunologic Unit code: 800000 CPT Code(s): 82104 Ref range: By report Reported: 2-4 days Alpha-1-Antitrypsin, Feces Order code: 80051 Preferred specimen: 5 g aliquot of stool in a clean unpreserved stool transport vial. Minimum specimen: 1 g stool Unacceptable: Specimens in media or preservatives. Transport temp: Frozen Method: Quantitative Enzyme-Linked Immunoassay Unit code: 800051 CPT Code(s): 82103 Ref range: 0.00-0.50 mg/g Reported: 1-3 days Alpha-2 Antiplasmin, Activity Order code: 80011 Preferred specimen: 1.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Centrifuge the light blue top tube to obtain platelet-poor plasma. Carefully remove the plasma without disturbing the cells using a plastic transfer pipette. Transfer the plasma into a plastic transport tube and freeze. Minimum specimen: 1.0 mL plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Serum or non-frozen or hemolyzed samples. Transport temp: CRITICAL FROZEN Method: Chromogenic Assay Unit code: 800100 CPT Code(s): 85410 Ref range: 18 years and older: 82-133% Reported: 1-8 days 10-69 Test List BBPL Directory of Services Alpha-2-Macroglobulin Order code: 84087 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.4 mL serum Other acceptable: 1.0 mL CSF and pleural fluid (centrifuge and separate to remove cellular material). Unacceptable: Hemolyzed specimens. Transport temp: Refrigerated Method: Nephelometry Unit code: 800150 CPT Code(s): 83883 Ref range: 131-293 mg/dL Reported: 1-5 days Alprazolam Order code: 86088 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 842150 CPT Code(s): 80154 Ref range: Dose-Related Range: Anxiety: 10-40 ng/mL (Dose: 1-4 mg/d) Phobia & panic: 50-100 ng/mL (Dose: 6-9 mg/d) Toxic: Greater than 100 ng/mL Reported: 1-4 days S1 0 ALT (SGPT) See: Alanine Aminotransferase Aluminum, Serum or Plasma Order code: 80460 Preferred specimen: 2.0 mL serum, royal blue (no additives) top tube. Remove serum from cells ASAP and transfer to a Trace Element-Free transport tube. Do not allow serum to remain on cells. Minimum specimen: 0.5 mL serum or plasma Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free tubes may be due to contamination. Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive). Other acceptable: 2.0 mL plasma, royal blue (EDTA) top tube. Remove plasma from cells ASAP and transfer to a Trace Element-Free transport tube. Do not allow plasma to remain on cells. Unacceptable: Separator tubes or gels and specimens that are not separated from the red cells, or clot, within 6 hours. Transport temp: Room temperature Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 802050 CPT Code(s): 82108 Ref range: 0-15 µg/L Serum aluminum greater than 50 µg/L is consistent with overload and may correlate with toxicity. Reported: 1-4 days Test List 10-70 BBPL Directory of Services Amantadine (Symmetrel) Order code: 80515 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 2.0 mL plasma, lavender (EDTA), green (sodium heparin) or gray (sodium fluoride/potassium oxalate) top tube. Unacceptable: Separator tubes. Transport temp: Refrigerated Method: Gas Chromatography Unit code: 802100 CPT Code(s): 80299 Ref range: By report Reported: Within 7 days Ambenyl, Serum See: Diphenhydramine Amikacin, Peak Order code: 80222 Preferred specimen: 1.0 mL serum, red top tube, or plasma, green (sodium heparin) top tube. Do not draw in SST. Remove serum or plasma from cells within 1 hour of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Draw 30 minutes following completion of drug infusion. Unacceptable: Citrate, EDTA, or oxalate/fluoride anticoagulants. Transport temp: Refrigerated Method: Immunoassay Unit code: 802202 CPT Code(s): 80150 Ref range: Optimal: 20.0-30.0 µg/mL Toxic: 30.1 µg/mL or greater Reported: Within 1-2 days S1 0 Amikacin, Random Order code: 80470 Preferred specimen: 1.0 mL serum, red top tube, or plasma, green (sodium heparin) top tube. Do not draw in SST. Remove serum or plasma from cells within 1 hour of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Test is for random sampling. Unacceptable: Citrate, EDTA, or oxalate/fluoride anticoagulants. Transport temp: Refrigerated Method: Immunoassay Unit code: 802200 CPT Code(s): 80150 Ref range: Trough Optimal: 4.0-8.0 µg/mL Toxic: 8.1 µg/mL or greater Peak Optimal: 20.0-30.0 µg/mL Toxic: 30.1 µg/mL or greater Reported: Within 1-2 days Amikacin, Trough Order code: 80221 Preferred specimen: 1.0 mL serum, red top tube, or plasma, green (sodium heparin) top tube. Do not draw in SST. Remove serum or plasma from cells within 1 hour of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Draw 5 to 90 minutes before next infusion. Unacceptable: Citrate, EDTA, or oxalate/fluoride anticoagulants. Transport temp: Refrigerated Method: Immunoassay Unit code: 802201 CPT Code(s): 80150 Ref range: Optimal: 4.0-8.0 µg/mL Toxic: 8.1 µg/mL or greater Reported: Within 1-2 days 10-71 Test List BBPL Directory of Services Amino Acid Quantitative, Plasma Order code: 80480 Preferred specimen: 0.5 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP and avoid collecting buffy coat material. Transfer plasma to a plastic transport tube and freeze ASAP. Separate specimens must be submitted when multiple test are ordered. Minimum specimen: 0.25 mL plasma Notes: Fasting specimens are preferred for adults. For infants and children draw specimen prior to feeding or 2-3 hours after a meal. Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. Please submit a completed Patient History for Biochemical Genetic Testing form with test request form and specimen. Unacceptable: Hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 800201 CPT Code(s): 82139 Ref range: By report Reported: 2-5 days Amino Acids Quantitative, Urine Order code: 80490 Preferred specimen: 4.0 mL urine aliquot from a well-mixed random urine. As soon as possible after urine has been obtained, mix the collection well, transfer the urine aliquot to a plastic transport container and freeze. Avoid dilute urine when possible. First morning urine is preferred. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 3.0 mL urine aliquot Notes: Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. Please submit a Patient History for Biochemical Genetic Testing form with the test request form and specimen. Transport temp: CRITICAL FROZEN Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 800249 CPT Code(s): 82139 Ref range: By report Reported: 3-7 days Aminolevulinic Acid (ALA), Urine Order code: 80530 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. Protect from light during collection, storage, and shipment. Submit specimen in an amber transport tube. Record total volume and hours of collection on both the transport tube and test request form. Minimum specimen: 1.2 mL urine aliquot Notes: Patient should refrain from alcohol consumption 24 hours prior to specimen collection. Specimen preservation with acid or base is discouraged and may cause assay interference. When collecting urine for additional tests that require acid or base preservation, the ALA aliquot should be removed prior to the addition of the acid or base. Unacceptable: Body fluids other than urine. Transport temp: Refrigerated Method: Ion Exchange Chromatography/Spectrophotometry Unit code: 802350 CPT Code(s): 82135 Ref range: Aminolevulinic Acid, Urine: 0-35 umol/L Aminolevulinic Acid, Urine: 0-60 umol/d Reported: 1-4 days Aminophylline See: Theophylline Test List 10-72 S1 0 BBPL Directory of Services Amiodarone & Metabolite Order code: 80540 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Remove serum or plasma from cells and transfer to a plastic amber transport tube. Protect from light. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 802400 CPT Code(s): 80299 Ref range: Therapeutic Range: Total (Amiodarone and Metabolite): 0.5-2.0 µg/mL Toxic Level: Greater than 3.0 µg/mL Reported: 1-4 days Amitriptyline & Nortriptyline Order code: 80550 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Includes values for amitriptyline, nortriptyline, and total. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 802450 CPT Code(s): 80152, 80182 Ref range: Therapeutic Range: Total drug: 95-250 ng/mL Toxic: > 500 ng/mL Reported: 1-5 days S1 0 Ammonia, Plasma Order code: 1043 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Tube must be properly filled, mixed well, and placed on ice immediately after collection. Plasma must be removed from cells and frozen within 15 minutes of collection. Patient should not clench fist during specimen collection. Minimum specimen: 0.5 mL frozen plasma Notes: Separate specimen must be submitted when multiple tests are ordered. Unacceptable: Grossly lipemic or hemolyzed EDTA plasma, nonfrozen plasma, serum specimens. Transport temp: CRITICAL FROZEN Method: Enzyme Immunoassay Unit code: 103005 CPT Code(s): 82140 Ref range: 19-94 µg/dL Reported: Within 24 hours Amniotic Bilirubin Scan Order code: 81171 Preferred specimen: 3.0 mL amniotic fluid in an amber plastic transport tube. Minimum specimen: 2.0 mL amniotic fluid. Notes: Protect from light during collection, storage, and shipment. Unacceptable: Specimens not protected from light. Transport temp: Refrigerated Method: Spectrophotometry (Delta OD 450 nm) Unit code: 804500 CPT Code(s): 82143 Ref range: Normal: 0.02 OD or less; depends on gestational age. Reported: 1-2 days 10-73 Test List BBPL Directory of Services Amoxapine & Metabolite Order code: 80600 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.7 mL serum or plasma Notes: Test includes Amozapine and 8-Hydroxy Amoxapine. Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography Unit code: 802750 CPT Code(s): 80299 Ref range: By report Reported: 3-5 days Amphetamine Confirmation, Quantitative, Urine Order code: 81291 Preferred specimen: 15 mL random urine in a clean plastic urine container. Minimum specimen: 7 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 812910 CPT Code(s): 82145 Ref range: By report Reported: 4-6 days Amphetamine, Serum or Plasma See: Drugs of Abuse Confirmation/Quantitation - Amphetamine, Serum or Plasma Amylase Isoenzyme Order code: 80610 Preferred specimen: 1.0 mL serum, SST. Allow specimen to clot completely at room temperature. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum or plasma Notes: Salivary amylase is calculated as the difference between the total and pancreatic amylase. Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP. Unacceptable: Body Fluids. Hemolyzed specimens. Transport temp: Refrigerated Method: Enzymatic Unit code: 802850 CPT Code(s): 82150 (x2) Ref range: Pancreatic Amylase: 6-35 months: 2-28 U/L 3-6 years: 8-34 U/L 7-17 years: 9-39 U/L 18 years and older: 12-52 U/L Salivary Amylase: 18 months and older: 9-86 U/L Total Amylase: 3-90 days: 0- 30 U/L 3-6 months: 7-40 U/L 7-8 months: 7-57 U/L 9-11 months: 11-70 U/L 12-17 months: 11-79 U/L 18-35 months: 19-92 U/L 3-4 years: 26-106 U/L 5-12 years: 30-119 U/L 13 years and older: 30-110 U/L Reported: 1-2 days Test List 10-74 S1 0 BBPL Directory of Services Amylase, Fluid Order code: 1533 Preferred specimen: 1.0 mL body fluid in a plastic transport tube. Minimum specimen: 0.5 mL fluid Notes: Indicate source on test request form. Transport temp: Refrigerated Method: Kinetic Unit code: 103175 CPT Code(s): 82150 Ref range: None established Reported: Within 24 hours Amylase, Serum Order code: 1300 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.3 mL serum Transport temp: Refrigerated Method: Kinetic Unit code: 103010 CPT Code(s): 82150 Ref range: 20-104 U/L Reported: Within 24 hours Amylase, Urine Order code: 1495 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24 hour urine collection. Refrigerate during collection. No preservative. Minimum specimen: 1.0 mL urine Notes: Record the total volume and hours of collection on both the specimen container and the test request form. Other acceptable: 5.0 mL random urine Transport temp: Refrigerated Method: Enzymatic Unit code: 102410 S1 0 CPT Code(s): 82150 Ref range: Reported: Within 24 hours ANA See: Anti-Nuclear Antibody Anti-Nuclear Antibody (ANA) Profile Anti-Nuclear Antibody with Reflex to ANA Profile Anti-Nuclear Antibody (ANA) Comprehensive Profile Anabolic Steroids, Urine Screen with Reflex to Confirmation Order code: 80281 Preferred specimen: 4.0 mL random urine. Minimum specimen: 1.6 mL urine Notes: Test includes: Bolasterone, Boldenone, Clenbuterol, Clostebol Metabolite, Clostebol, Creatinine, Drostanolone Metabolite, Epitestosterone, Fluoxymesterone, Methandienone Metabolite, Methandienone, Methenolone, Methyltestosterone, Nandrolone Metabolite, Nandrolone, Norandrostenedione, Norethandrolone Metabolite, Norethandrolone, Norethindrone, Oxandrolone, Oxymetholone Metabolite, Probenecid, Stanozolol Metabolite, Stanozolol, Testosterone/Epitestosterone Ratio, Testosterone, Tetrahydrogestrinone, Trenbolone Metabolite, Turinabol. If this test detects the presence of any of the included steroids, confirmation testing will be added at no additional charge. Transport temp: Refrigerated Method: Qualitative Colorimetry/High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 802861 CPT Code(s): 80100, 82570 Ref range: By report Reported: 3-8 days Anafranil See: Clomipramine & Metabolite 10-75 Test List BBPL Directory of Services Anaplasma Phagocytophilum (HGA) Antibodies, IgG & IgM Order code: 80287 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.05 mL serum Unacceptable: Heat inactivated, lipemic, hemolytic, icteric, turbid, or bacterially contaminated specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 802875 CPT Code(s): 86666 (x2) Ref range: Anaplasma phagocytophilum (HGA) Antibody, IgG: Less than 1:80 - No significant level of IgG antibodies to A. phagocytophilum detected. Greater than or equal to 1:80 - Suggestive of a recent or past infection with A. phagocytophilum Anaplasma phagocytophilum (HGA) Antibody, IgM: Less than 1:16 - No significant level of IgM antibodies to A. phagocytophilum detected. Greater than or equal to 1:16 - Suggestive of a current or recent infection with A. phagocytophilum. Reported: 1-5 days ANCA See: Anti-Neutrophil Cytoplasmic Antibodies Androstenedione Order code: 80640 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in gel-barrier tubes. Remove serum from cells and transfer to plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Gross hemolysis, lipemia, or separator tubes or gels. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 803150 CPT Code(s): 82157 Ref range: By report Reported: 1-3 days Angiotensin Converting Enzyme (ACE) S1 0 Order code: 80660 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Notes: Stop administration of captopril, enalapril, or lisinopril for 12 hours prior to venipuncture (reduces ACE activity). Unacceptable: Whole blood, EDTA or heparinized plasma, CSF, hemolyzed or icteric specimens. Captopril, enalapril, or lisinopril administration. Transport temp: Refrigerated Method: Kinetic Unit code: 803250 CPT Code(s): 82164 Ref range: 0-2 years: 18-95 units/L 3-14 years: 22-108 units/L 15 years or older: 14-82 units/L Reported: 1-2 days Angiotensin Converting Enzyme (ACE), CSF Order code: 80321 Preferred specimen: 1.0 mL CSF. Transfer CSF to a plastic transport tube and freeze. Minimum specimen: 0.3 mL CSF Unacceptable: Hemolyzed or xanthochromic specimens. Transport temp: Frozen Method: Quantitative Spectrophotometry Unit code: 803251 CPT Code(s): 82164 Ref range: 0.0-2.5 U/L Reported: 1-5 days Test List 10-76 BBPL Directory of Services Angiotensin II Order code: 80326 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Keep cold during centrifugation. Minimum specimen: 0.3 mL plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Specimens received at room temperature or refrigerated. Hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Immunoassay Unit code: 803256 CPT Code(s): 82163 Ref range: By report Reported: 3-13 days Ankylosing Spondylitis (HLA-B27) Genotyping Order code: 80026 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Notes: Aids in diagnosis of individuals with suspicious symptoms for ankylosing spondylitis or other related conditions. Counseling and informed consent form recommended for genetic testing. Molecular Genetic Testing consent forms are available through BBPL Client Services. Unacceptable: Frozen whole blood. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Fluorescence Monitoring Unit code: 803260 CPT Code(s): 81374 Ref range: Negative: The specimen is negative for HLA-B27. Positive: The specimen is positive for HLA-B27. Reported: 2-5 days Anti-Cardiolipin Antibodies, IgG, IgM See: Cardiolipin Antibodies, IgG, IgM S1 0 Anti-Cardiolipin Antibodies, IgG, IgM, IgA See: Cardiolipin Antibodies, IgG, IgM, IgA Anti-Cardiolipin Antibody, IgA See: Cardiolipin Antibody, IgA Anti-Cardiolipin Antibody, IgG See: Cardiolipin Antibody, IgG Anti-Cardiolipin Antibody, IgM See: Cardiolipin Antibody, IgM Anti-Diuretic Hormone See: Arginine Vasopressin Anti-DNA Antibody, Double Stranded See: dsDNA Antibody, IgG Anti-DNA Antibody, Single Stranded See: ssDNA Antibody, IgG 10-77 Test List BBPL Directory of Services Anti-DNase-B, Streptococcal Antibody Order code: 80710 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.4 mL serum Unacceptable: Plasma or severely hemolyzed specimens. Transport temp: Refrigerated Method: Nephelometry Unit code: 812350 CPT Code(s): 86215 Ref range: 0-6 years: Less than 250 U/mL 7-17 years: Less than 310 U/mL 18 years and older: Less than 260 U/mL Reported: 1-4 days Anti-Extractable Nuclear Antigen, (ENA) See: Sm/RNP Antibody IgG Anti-GBM Antibody Panel See: Glomerular Basement Membrane Antibody Panel Anti-Glomerular Basement Membrane Antibody Panel See: Glomerular Basement Membrane Antibody Panel Anti-Histone Antibodies Order code: 80765 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Hemolysis, icterus, lipemia, or bacterial contamination. Transport temp: Room temperature S1 0 Method: Enzyme-Linked Immunosorbent Assay Unit code: 819750 CPT Code(s): 83516 Ref range: Negative: <1.0 Units Weak Positive: 1.0-1.5 Units Moderate Positive: 1.6-2.5 Units Strong Positive: >2.5 Units Reported: 1-4 days Anti-Infliximab Antibody See: Infliximab (IFX) Concentration + IFX Antibody Anti-Islet Cells See: Islet Cell Antibody Anti-Microsomal Antibodies See: Thyroid Peroxidase Antibodies Anti-Mitochondrial Antibody See: Mitochondrial M2 Antibody, IgG Test List 10-78 BBPL Directory of Services Anti-Mullerian Hormone Order code: 80305 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 0.2 mL serum Unacceptable: Room temperature specimens. Hemolyzed or lipemic specimens. Transport temp: Frozen Method: Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 803405 CPT Code(s): 83520 Ref range: Female: 0-16 years: 0.0-7.1 ng/mL 17-29 years: 0.85-14.24 ng/mL 30-39 years: 0.51-7.27 ng/mL 40-49 years: 0.00-6.21 ng/mL 50 years and older: 0.00-0.82 ng/mL Male: 0-13 days: 15.50-48.10 ng/mL 14 days-11 months: 39.10-91.10 ng/mL 12 months-6 years: 48.00-83.20 ng/mL 7-8 years: 33.80-60.20 ng/mL 9-12 years: 6.1-60.7 ng/mL 13-16 years: 2.3-33.1 ng/mL Adult males (17 and older): 1.50-18.35 ng/mL Reported: Within 4 days Anti-Neutrophil Cytoplasmic Antibodies Order code: 5123 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.5 mL serum Notes: Includes Protease-3 Antibody (PR3) and Myeloperoxidase Antibody (MPO). Unacceptable: Severely hemolyzed, lipemic, icteric, or contaminated samples. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 360700 CPT Code(s): 83516 (x2) S1 0 Ref range: <4.0 EU/mL No antibody detected 4.0-5.9 EU/mL Inconclusive >5.9 EU/mL Positive Reported: 1-6 days Anti-Nuclear Antibody (ANA) Order code: 5100 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: If screen is positive, a titer and pattern will be reported. Unacceptable: Plasma or whole blood. Grossly contamimated, hemolyzed, lipemic, or icteric sera. Transport temp: Refrigerated Method: Enzyme Immunoassay/Indirect Fluorescent Antibody (Hep-2) Unit code: 350099 CPT Code(s): 86038 Ref range: None Detected Reported: 1-3 days 10-79 Test List BBPL Directory of Services Anti-Nuclear Antibody (ANA) Comprehensive Profile Order code: 94093 Preferred specimen: 5.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 3.0 mL serum Notes: Test includes: Anti-Nulcear Antibody dsDNA Antibody, IgG Sm/RNP Antibody, IgG SSA (Ro) Antibody, IgG SSB (La) Antibody, IgG Scleroderma (Scl-70) Antibody, IgG Jo-1 Antibody, IgG If the Anti-Nuclear Antibody screen is positive, a titer and pattern will be reported. Unacceptable: Plasma, severely hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay/Indirect Fluorescent Antibody (Hep-2) Unit code: 94093 CPT Code(s): 86038, 86225, 86235 (x5) Ref range: See individual tests. Reported: Within 1-3 days Anti-Nuclear Antibody (ANA) Profile Order code: 5105 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: Test includes: dsDNA Antibody, IgG Sm/RNP Antibody, IgG SSA (Ro) Antibody, IgG SSB (La) Antibody, IgG Scleroderma (Scl-70) Antibody, IgG Jo-1 Antibody, IgG Unacceptable: Plasma, severely hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 350110 CPT Code(s): 86225, 86235 (x5) S1 0 Ref range: See individual tests Reported: 1-3 days Anti-Nuclear Antibody with Reflex to ANA Profile Order code: 5016 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum Notes: A positive ANA screen by EIA will be confirmed by IFA titer and pattern. If the titer is >= 1:160, the ANA Profile will be added at an additional charge. ANA Profile includes: dsDNA Antibody, IgG Sm/RNP Antibody, IgG SSA (Ro) Antibody, IgG SSB (La) Antibody, IgG Scleroderma (Scl-70) Antibody, IgG Jo-1 Antibody, IgG Unacceptable: Plasma or whole blood. Grossly contamimated, hemolyzed, lipemic, or icteric sera. Transport temp: Refrigerated Method: Enzyme Immunoassay/Indirect Fluorescent Antibody (Hep-2) Unit code: 350106 CPT Code(s): 86038 Ref range: None Detected Reported: 1-3 days Anti-Parietal Cell Antibody, IgG See: Parietal Cell Antibody, IgG Anti-Phospholipid Antibodies IgG, IgM, IgA See: Cardiolipin Antibodies, IgG, IgM, IgA Anti-Phospholipid Antibodies, IgG, IgM See: Cardiolipin Antibodies, IgG, IgM Test List 10-80 BBPL Directory of Services Anti-Phospholipid Antibody IgA See: Cardiolipin Antibody, IgA Anti-Phospholipid Antibody IgG See: Cardiolipin Antibody, IgG Anti-Phospholipid Antibody IgM See: Cardiolipin Antibody, IgM Anti-Sjogrens Antibody See: SSA (Ro) Antibody IgG SSB (La) Antibody IgG Anti-Streptolysin O Order code: 5060 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens Transport temp: Refrigerated Method: Nephelometry Unit code: 350150 CPT Code(s): 86060 Ref range: Adult: <200 IU/mL Pediatric:<100 IU/mL Reported: 1-3 days Anti-Striated Muscle Antibody S1 0 See: Striated Muscle Antibody, IgG with Reflex to Titer Anti-Thyroglobulin Antibody See: Thyroglobulin Antibody Anti-Thyroid Microsomal Antibody See: Thyroid Peroxidase Antibodies Anti-Xa Heparin See: Heparin Anti-Xa Antibody ID Order code: 5055 Preferred specimen: One 7 mL lavender (EDTA) top tube. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 4.0 mL whole blood, lavender (EDTA) top tube Notes: Specimen should be labeled with patient name, date of birth, social security number and collection date. Transport temp: Refrigerated Method: Hemagglutination Unit code: 399003 CPT Code(s): 86870 Ref range: By report Reported: 1-2 days 10-81 Test List BBPL Directory of Services Antibody Screen Order code: 5040 Preferred specimen: One 7 mL lavender (EDTA) top tube. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 4.0 mL whole blood, lavender (EDTA) top tube Notes: Specimen should be labeled with patient name, date of birth, social security number and collection date. Transport temp: Refrigerated Method: Hemagglutination Unit code: 300300 CPT Code(s): 86850 Ref range: By report Reported: 1-2 days Antibody Titer Order code: 5056 Preferred specimen: One 7 mL lavender (EDTA) top tube. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 4.0 mL whole blood, lavender (EDTA) top tube Notes: Specimen should be labeled with patient name, date of birth, social security number and collection date. Transport temp: Refrigerated Method: Hemagglutination Unit code: 399004 CPT Code(s): 86886 Ref range: By report Reported: 1-2 days Antibody to Scl-70 See: Scleroderma (Scl-70) Antibody Antigen Test, Red Blood Cell Order code: 5052 Preferred specimen: One 7 mL lavender (EDTA) top tube. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 4.0 mL whole blood, lavender (EDTA) top tube Notes: Specimen should be labeled with patient name, date of birth, social security number and collection date. Indicate specific RBC antigen(s) required and patient history on test request form. Transport temp: Refrigerated Method: Hemagglutination Unit code: 399005 CPT Code(s): 86905 Ref range: By report Reported: 1-2 days Antimony, Urine Order code: 80776 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Specimen must be collected in a plastic container and should be refrigerated during collection period. Submit urine in two Trace Element-Free transport tubes. Do not use acid preservative. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician) prior to specimen collection. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 803400 CPT Code(s): 83018 Ref range: Antimony, Urine - per volume: 0-2 µg/L Antimony, Urine - per 24-hour: 0-2.5 µg/d Antimony, Urine - ratio to CRT: No reference interval (µg/g crt) Reported: 1-5 days Antipancreatic Islet Cells See: Islet Cell Antibody Test List 10-82 S1 0 BBPL Directory of Services Antiphospholipid Syndrome Profile Order code: 94555 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP, transfer to a plastic transport tube and refrigerate. and 6.0 mL platelet-poor plasma, three 3.5 mL light blue (3.2% sodium citrate) top tubes. Centrifuge immediately and remove the top two-thirds of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer 2.0 mL plasma into 3 separate plastic transport tubes and freeze immediately. Blue top tubes must be filled to completion to ensure a proper blood to anticoagulant ratio. Mix the tubes immediately by gentle inversion at least 6 times to ensure adequate mixing of the anticoagulant with the blood. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.6 mL serum and three 1.0 mL aliquots of platelet-poor plasma Notes: Test includes: Cardiolipin Antibodies, IgG, IgM Lupus Anticoagulant (LA) Screen & Confirmatory Unacceptable: Hemolyzed, icteric, lipemic, or clotted specimens. Whole blood, specimens contaminated with heparin, or specimens not stored at the proper temperature. Transport temp: Serum, refrigerated; Plasma, frozen Method: Enzyme Immunoassay/Photo optic Unit code: 94555 CPT Code(s): 85613, 85732, 86147 (x2) Ref range: By report Reported: 1-3 days Antithrombin III, Functional See: Antithrombin, Enzymatic (Activity) Antithrombin Panel (Antithrombin, Enzymatic & Antithrombin, Antigen) Order code: 83305 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Chromogenic Assay/Microlatex Particle-Mediated Immunoassay S1 0 Unit code: 839305 CPT Code(s): 85300, 85301 Ref range: Antithrombin, Enzymatic Activity: 18 year or older: 76-128% Antithrombin, Antigen: 82-136% Reported: 1-2 days Antithrombin, Enzymatic (Activity) Order code: 83931 Preferred specimen: 1.5 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove the plasma from cells and transfer to a plastic transport tube. Freeze immediately. Minimum specimen: 1.0 mL platelet poor plasma. Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Serum, nonfrozen, or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Chromogenic Assay Unit code: 839310 CPT Code(s): 85300 Ref range: 1-4 days: 39-87% 5-29 days: 41-93% 30-89 days: 48-108% 90-179 days: 73-121% 180-364 days: 84-124% 1-5 years: 82-139% 6 years: 90-131% 7-9 years: 90-135% 10-11 years: 90-134% 12-13 years: 90-132% 14-15 years: 90-131% 16-17 years: 87-131% 18 years and older: 76-128% Reported: 1-2 days APO E Genotype, Cardiovascular See: Apolipoprotein E (APOE) 2 Mutations, Cardiovascular Risk 10-83 Test List BBPL Directory of Services Apocard See: Flecainide Apolipoprotein A-1 Order code: 80343 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 1.0 mL serum or plasma Notes: Patient must be fasting 12-14 hours. Record patient's sex on test request form. Other acceptable: 2.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP. Unacceptable: Specimen from nonfasting patient. Transport temp: Refrigerated Method: Immunologic Unit code: 803430 CPT Code(s): 82172 Ref range: Male: 110-180 mg/dL Female: 110-205 mg/dL Reported: 1-3 days Apolipoprotein A-1 & B Order code: 83432 Preferred specimen: 4.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 2.0 mL serum or plasma Notes: Patient must be fasting 12-14 hours. Record patient's sex on test request form. Other acceptable: 4.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP. Unacceptable: Specimen from nonfasting patient. Transport temp: Refrigerated Method: Immunologic Unit code: 803432 CPT Code(s): 82172 (x2) Ref range: Apolipoprotein A-1: Male: 110-180 mg/dL Female: 110-205 mg/dL S1 0 Apolipoprotein B: Male: 0-79 mg/dL Female: 0-79 mg/dL Reported: 2-3 days Apolipoprotein B Order code: 80341 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 1.0 mL serum or plasma Notes: Patient must be fasting 12-14 hours. Other acceptable: 2.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP. Unacceptable: Specimen from nonfasting patient. Transport temp: Refrigerated Method: Immunologic Unit code: 803431 CPT Code(s): 82172 Ref range: 0-79 mg/dL Reported: 1-3 days Apolipoprotein E (APOE) 2 Mutations, Cardiovascular Risk Order code: 80438 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Notes: Please submit Patient History for Molecular Genetic Testing and test request form along with specimen. Use to detect APOE mutations in individuals with a suspicion of type III hyperlipoproteinemia (familial hyperlipoproteinemia). This test is for cardiovascular risk assessment only and must not be ordered for assessing Alzheimer disease in a demented patient. This test is not recommended for nonsymptomatic patients under 18 years of age. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Fluorescence Monitoring Unit code: 803438 CPT Code(s): 81401 Ref range: Homozygous apo e3 (e3/e3): This genotype is the most common (normal) genotype. Reported: 2-7 days Test List 10-84 BBPL Directory of Services APTT See: Partial Thromboplastin Time (PTT) Aquaporin-4 Receptor Antibody Order code: 80344 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.3 mL serum Unacceptable: Contaminated, hemolyzed, icteric and lipemic specimens. Plasma, CSF, amniotic fluid, synovial fluid, peritoneal fluid, and ocular fluid. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 803445 CPT Code(s): 83516 Ref range: Negative: 4 U/mL or less Indeterminate: 5 U/mL Positive: 6 U/mL or greater Approximately 75% of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor. Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis. While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO. Reported: 1-8 days Arava See: Leflunomide Metabolite Arboviral Encephalitis AB, IgM Order code: 83455 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Test includes: California Encephalitis Antibodies, IgM St Louis Encephalitis Antibodies, IgM Eastern Equine Encephalitis Antibodies, IgM Western Equine Encephalitis Antibodies, IgM S1 0 Transport temp: Refrigerated Method: Indirect Fluorescent Antibody (IFA) Unit code: 803455 Ref range: Negative Reported: 3-7 days Arboviral Encephalitis Antibodies, IgG Order code: 83453 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Test includes: California Encephalitis Antibodies, IgG St Louis Encephalitis Antibodies, IgG Eastern Equine Encephalitis Antibodies, IgG Western Equine Encephalitis Antibodies, IgG Transport temp: Refrigerated Method: Indirect Fluorescent Antibody (IFA) Unit code: 803453 Ref range: Negative Reported: 3-7 days Arginine Vasopressin Hormone Order code: 80920 Preferred specimen: 6.0 mL plasma, three 5 mL lavender (EDTA) top tubes. Remove plasma from cells ASAP, transfer into two plastic transport tubes and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 2.5 mL plasma Unacceptable: Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Radioimmunoassay Unit code: 803300 CPT Code(s): 84588 Ref range: 0.0-6.9 pg/mL Reported: 3-11 days 10-85 Test List BBPL Directory of Services Aroclors See: Polychlorinated Biphenyls Screen with Reflex to Confirmation Arsenic Analysis, Hair Order code: 83551 Preferred specimen: Collect a pencil-thick segment of hair. Bundle, cut at roots, wrap with twist tie at root end. Transfer 500 mg hair to a Trace ElementFree Transport tube. Minimum specimen: 500 mg hair Notes: Exposure Monitoring/Investigation; not for clinical diagnostic purposes. Transport temp: Room temperature. Refrigerated or frozen also acceptable. Method: Quantitative Inductively Coupled Plasma/Mass Spectrometry Unit code: 803551 CPT Code(s): 80103, 82175 Ref range: By report Reported: 7-14 days Arsenic, Blood Order code: 80950 Preferred specimen: 7 mL whole blood, royal blue (K EDTA) or (Na EDTA) top tube, in the original collection tube at room temperature or refrigerated 2 2 is also acceptable. Minimum specimen: 0.5 mL whole blood Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patient should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) and avoid shellfish and seafood for 48 to 72 hours. Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na EDTA) tube. 2 Unacceptable: Heparin anticoagulant or frozen specimens. Transport temp: Room temperature Method: Quantitative Inductively Coupled Plasma/Mass Spectrometry Unit code: 803500 CPT Code(s): 82175 Ref range: 0.0-13.0 µg/L Potentially toxic ranges for blood arsenic: greater than or equal to 600 µg/L. Blood arsenic is for the detection of recent exposure poisoning only. Blood arsenic levels in healthy subjects vary considerably with exposure to arsenic in the diet and the environment. A 24-hour urine arsenic is useful for the detection of chronic exposure. Reported: 1-3 days Arsenic, Urine with Reflex to Fractionated Order code: 80980 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random collection. Specimen must be collected in a plastic container and should be refrigerated during collection. Submit urine in two trace element-free transport tubes. Do not use acid preservative. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 2.0 mL urine aliquot. Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. If total arsenic concentration is between 35-2000 µg/L, then Arsenic, Fractionated, will be added to determine the proportion of organic, inorganic, and methylated species. Additional charges apply. It may be appropriate to request fractionation for specimens with a total arsenic greater than 30 µg/gCRT despite a total arsenic concentration less than 35 µg/L. If low-level chronic poisoning is suspected, the µg/gCRT ratio may be a more sensitive indicator of arsenic exposure than the total arsenic concentration. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies) or acid preserved urine. Transport temp: Refrigerated Method: Quantitative High Pressure Liquid Chromatography/Quantitative Inductively Coupled Plasma-Mass Spectrometry Unit code: 803650 CPT Code(s): 82175 Ref range: Arsenic, Urine: 0-35.0 µg/L Arsenic, Urine (24-hour): 0-50.0 µg/d Reported: 1-5 days Artane See: Trihexyphenidyl Test List 10-86 S1 0 BBPL Directory of Services Arthritic Series Order code: 94504 Preferred specimen: 3.0 mL serum, red top tube or SST, and 1 lavender top tube (EDTA whole blood). Minimum specimen: See individual tests. Notes: Test includes: Anti-Nuclear Antibody Anti-Streptolysin O Rheumatoid Factor Sedimentation Rate Uric Acid Unacceptable: See individual tests. Transport temp: Refrigerated Method: See individual tests. Unit code: 94504 CPT Code(s): 84550, 85651, 86038, 86060, 86431 Ref range: See individual tests. Reported: 1-3 days Arthritic Series I Order code: 5310 Preferred specimen: 3.0 mL serum, red top tube or SST. Minimum specimen: See individual tests. Notes: Test includes: Anti-Nuclear Antibody Anti-Streptolysin O C-Reactive Protein Rheumatoid Factor Uric Acid Unacceptable: See individual tests. Transport temp: Refrigerated Method: See individual tests. Unit code: 94500 CPT Code(s): 84550, 86038, 86060, 86140, 86430 Ref range: See individual tests. Reported: 1-3 days S1 0 Arthritic Series II Order code: 5311 Preferred specimen: 3.0 mL serum, red top tube or SST and 1 lavender top tube (EDTA whole blood). Minimum specimen: See individual tests. Notes: Test includes: Anti-Nuclear Antibody Anti-Streptolysin O C-Reactive Protein Rheumatoid Factor Sedimentation Rate Uric Acid Unacceptable: See individual tests. Transport temp: Refrigerated Method: See individual tests. Unit code: 94501 CPT Code(s): 84550, 85651, 86038, 86060, 86140, 86431 Ref range: See individual tests. Reported: 1-3 days Arthritis Panel Order code: 94505 Preferred specimen: 3.0 mL serum, red top tube or SST and 1 lavender (EDTA) top tube, 3.0 mL whole blood. Minimum specimen: 1.5 mL serum and 1.0 mL EDTA whole blood Notes: Test includes: Anti-Nuclear Antibody Rheumatoid Factor Sedimentation Rate Uric Acid Unacceptable: Extremely lipemic serum. Transport temp: Refrigerated Method: See individual tests. Unit code: 94505 CPT Code(s): 84550, 85651, 86038, 86431 Ref range: See individual tests. Reported: 1-3 days 10-87 Test List BBPL Directory of Services Arylsulfatase A Deficiency, Leukocytes Order code: 81000 Preferred specimen: 15.0 mL whole blood, yellow (ACD Solution A or B) top tubes. Refrigerate specimen after collection and transport to the laboratory within 24 hours of collection. Transport specimen on cool pack. Do not allow sample to freeze. Minimum specimen: 10.0 mL whole blood Notes: Collect specimens Monday through Thursday only. Specimens must be received in the laboratory within 24 hours of collection. Unacceptable: Frozen specimens. Transport temp: Refrigerated Method: Ezymatic activity with p-nitrocatechol sulfate Unit code: 803750 CPT Code(s): 82657 Ref range: 25.0-90.0 nmol/hour/mg protein Reported: Within 10 days Ascorbic Acid See: Vitamin C, Plasma Asendin, Serum See: Amoxapine ASO See: Anti-Streptolysin O Aspartate Aminotransferase (AST) Order code: 1105 Preferred specimen: 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated S1 0 Method: Kinetic Unit code: 101800 CPT Code(s): 84450 Ref range: 0-41 U/L Reported: Within 24 hours Aspergillus Antibodies by Immunodiffusion Order code: 81010 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: This test uses culture filtrates of Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, and Aspergillus terreus. Unacceptable: Body fluids Transport temp: Refrigerated Method: Qualitative Immunodiffusion Unit code: 803800 CPT Code(s): 86606 Ref range: None detected In general, immunodiffusion measures IgG and a positive result may suggest past infection. The test is positive in about 90% of sera from patients with aspergilloma and 50-70% of patients with allergic bronchopulmonary aspergillosis. A negative test (none detected) does not exclude aspergillosis. Reported: 2-4 days Test List 10-88 BBPL Directory of Services Aspergillus Galactomannan Antigen, Serum Order code: 80385 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL serum Unacceptable: Plasma. Separator tubes or gels. Hemolyzed specimens. Transport temp: Frozen Method: Semi-quantitative Enzyme Immunoassay Unit code: 803805 CPT Code(s): 87305 Ref range: Aspergillus Galactomannan Antigen, Serum: Negative Aspergillus Galactomannan Index: By report Negative results do not exclude the diagnosis of invasive aspergillosis. A single positive test result (index equal to or greater than 0.5) should be clinically correlated by testing a separate serum specimen because many agents (e.g. foods, antibiotics) may crossreact with the test. If invasive aspergillosis is suspected in high-risk patients, serial sampling is recommended. Reported: 1-2 days Aspirin See: Salicylate AST (SGOT) See: Aspartate Aminotransferase (AST) Ativan See: Lorazepam Aventyl See: Nortriptyline S1 0 B-Cell CD20 See: CD20 - B Cells B-Cell Clonality Screening by PCR Order code: 81624 Preferred specimen: 5.0 mL whole blood, lavender top tube or 3.0 mL bone marrow (EDTA). Transport refrigerated. Or fresh tissue (100 mg or 0.5-2.0 cm³) transferred to a sterile container and frozen immediately. Or FFPE tumor tissue, formalin fix (10% neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Ship in cooled container during summer months. Transport tissue block at room temperature or refrigerated. Tissue block will be returned after testing. Tissue transport kits are available through BBPL Client Services for transporting tissue (frozen or paraffin block). Minimum specimen: 1.0 mL whole blood, bone marrow, CSF or pleural fluid. Notes: Record source on test request form. Testing includes pathologist's interpretation. Other acceptable: 3.0 mL CSF or pleural fluid is also acceptable but will be performed with disclaimer. Indicate on test request form to perform with disclaimer. Transport refrigerated. Unacceptable: Frozen whole blood or bone marrow. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens. Transport temp: Whole blood or Bone marrow: Refrigerated Fresh tissue: Frozen on dry ice. FFPE tumor tissue: Room temperature or refrigerated. Method: Polymerase Chain Reaction/Capillary Electrophoresis Unit code: 816214 CPT Code(s): 81261, 81264, G0452 Ref range: By report Reported: 5-7 days 10-89 Test List BBPL Directory of Services B-Type Natriuretic Peptide Order code: 1146 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL EDTA plasma Unacceptable: Frozen whole blood. Specimens collected in non-EDTA tubes. Specimens frozen in separator tubes. Room temperature plasma more than 8 hours old. Refrigerated or room temperature whole blood specimens more than 24 hours old. Hemolyzed specimens. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 114160 CPT Code(s): 83880 Ref range: A BNP value greater than 100 pg/mL is consistent with the diagnosis of congestive heart failure in the appropriate clinical setting. Reported: Within 24 hours B12, Vitamin See: Vitamin B12 Babesia microti Antibodies, IgG & IgM Order code: 82599 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.1 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Unacceptable: CSF. Lipemic, hemolyzed, or bacterially contaminated specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 825990 CPT Code(s): 86753 (x2) Ref range: Babesia microti Antibody, IgG by IFA: < 1:16 Negative - No significant level of detectable Babesia IgG antibody. 1:16 Equivocal - Repeat testing in 10-14 days may be helpful. > 1:16 Positive - IgG antibody to Babesia detected, which may indicate a current or past infection. Babesia microti Antibody, IgM by IFA: < 1:20 Negative - No significant level of detectable Babesia IgM antibody. 1:20 Equivocal - Repeat testing in 10-14 days may be helpful. > 1:20 Positive - IgM antibody to Babesia detected, which may indicate a current or recent infection. S1 0 Reported: 1-9 days Bacterial Antigens Order code: 81055 Preferred specimen: 2.0 mL serum, red top tube or SST, or 10.0 mL random urine in plastic urine containter, or 1.0 mL CSF in sterile plastic transport tube. Specimen must be received in laboratory within 48 hours of collection. Indicate source on test request form. Minimum specimen: 2.0 mL serum, 10.0 mL urine, or 1.0 mL CSF. Notes: Test includes: Qualitative determination of the presence of antigens of H influenzae, S pneumoniae, N meningitidis, a limited number to serogroups, and group B Streptococcus. Unacceptable: Hemolyzed, lipemic, or gross bacterial contaminated specimens. Transport temp: Refrigerated Method: Latex agglutination (LA) Unit code: 804000 CPT Code(s): 87802, 87899 (x3) Ref range: Negative Limitations: Test may be negative in early meningitis. Does not replace Gram stain and culture. The sensitivity of the tests vary from 50% to 100% depending on the specificity of the antibody and the concentration of antigen in the specimen. This test was most useful for the detection of serious H influenzae infection. Because of the availability of vaccine, this test is of extremely limited value. Reported: 2-5 days Bactrim See: Sulfonamides (Sulfas) Banzel See: Rufinamide Test List 10-90 BBPL Directory of Services Barbiturate Confirmation, Quantitative, Urine Order code: 81292 Preferred specimen: 15 mL random urine in a clean plastic urine container. Minimum specimen: 7 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Test includes: Amobarbital, Secobarbital, Butalbital, Pentobarbital, and Phenobarbital. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 812912 CPT Code(s): 82205 Ref range: By report Reported: 2-4 days Barbiturates Detection Order code: 81080 Preferred specimen: 2.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.6 mL serum or plasma Other acceptable: 2.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Gas Chromatography (GC) Unit code: 804200 CPT Code(s): 82205 Ref range: By report Reported: 2-5 days Barbiturates, Serum or Plasma See: Drugs of Abuse Confirmation/Quantitation - Barbiturates, Serum or Plasma S1 0 Bartonella henselae Antibodies, IgG & IgM Order code: 85255 Preferred specimen: 1.0 mL serum, SST or red top tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent." Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 836325 CPT Code(s): 86611 (x2) Ref range: Bartonella henselae Antibody, IgG by IFA: <1:64 Negative - No significant level of Bartonella henselae IgG antibody detected. 1:64-1:128 Equivocal - Questionable presence of Bartonella henselae IgG antibody detected. Repeat testing in 10-14 days may be helpful. >=1:256 Positive - Presence of IgG antibody to Bartonella henselae detected, suggestive of current or past infection. Bartonella henselae Antibody, IgM by IFA: <1:16 Negative - No significant level of Bartonella henselae IgM antibody detected. >=1:16 Positive - Presence of IgM antibody to Bartonella henselae detected, suggestive of current or recent infection. Reported: 1-8 days 10-91 Test List BBPL Directory of Services Bartonella henselae Antibody, IgG Order code: 85254 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent." Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody Unit code: 836324 CPT Code(s): 86611 Ref range: <1:64 Negative - No significant level of Bartonella henselae IgG antibody detected. 1:64-1:128 Equivocal - Questionable presence of Bartonella henselae IgG antibody detected. Repeat testing in 10-14 days may be helpful. >= 1:256 Positive - Presence of IgG antibody to Bartonella henselae detected, suggestive of current or past infection. Reported: 1-8 days Bartonella henselae Antibody, IgM Order code: 85256 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent." Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody Unit code: 836326 CPT Code(s): 86611 Ref range: < 1:16 Negative - No significant level of Bartonella henselae IgM antibody detected. >= 1:16 Positive - Presence of IgM antibody to Bartonella henselae detected, suggestive of current or recent infection. Reported: 1-8 days Bartonella quintana Antibodies, IgG & IgM Order code: 80426 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Notes: Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples. Please label samples as acute or convalescent. Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 804260 CPT Code(s): 86611 (x2) Ref range: Bartonella quintana Antibody, IgG: < 1:64 Negative - No significant level of Bartonella quintana IgG antibody detected. 1:64-1:128 Equivocal - Questionable presence of Bartonella quintana IgG antibody detected. Repeat testing in 10-14 days may be helpful. >= 1:256 Positive - Presence of IgG antibody to Bartonella quintana detected, suggestive of current or past infection. Bartonella quintana Antibody, IgM: < 1:16 Negative - No significant level of Bartonella quintana IgM antibody detected. >= 1:16 Positive - Presence of IgM antibody to Bartonella quintana detected, suggestive of current or recent infection. Reported: 1-8 days Bartonella Species by PCR, Whole Blood Order code: 80465 Preferred specimen: 1.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 0.5 mL whole blood Notes: Specimen source is required. Do not freeze specimen. Unacceptable: Plasma or heparinized specimens. Frozen specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 804265 CPT Code(s): 87471 Ref range: By report Reported: 1-5 days Test List 10-92 S1 0 BBPL Directory of Services Basic Metabolic Panel Order code: 1137 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Notes: Test includes: BUN Calcium Carbon Dioxide Chloride Creatinine Glucose Potassium Sodium Glomerular Filtration Rate Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: See individual tests Unit code: 90127 CPT Code(s): 80048 Ref range: BUN Calcium Carbon Dioxide Chloride Creatinine Glucose Potassium Sodium 10-26 mg/dL 8.5-10.5 mg/dL 20-32 mmol/L 98-110 mmol/L 0.4-1.5 mg/dL 70-99 mg/dL 3.5-5.0 mmol/L 136-145 mmol/L Reported: Within 24 hours BCL1 See: IGH/BCL-1 FISH Study BCL6 Rearrangement See: Chromosome Analysis, FISH-Interphase S1 0 BCR-ABL Major (p210) Quantitative by PCR Order code: 50110 Preferred specimen: 5.0 mL whole blood, lavender (EDTA), yellow (ACD solution A), light blue (sodium citrate), or green (sodium or lithium heparin) top tube. Refrigerate immediately after collection. Specimen should be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Testing includes pathologist's interpretation. Other acceptable: 3.0 mL bone marrow (EDTA) Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 550110 CPT Code(s): 81206, G0452 Ref range: By report Reported: 2-7 days BCR-ABL Minor (p190) Quantitative by PCR Order code: 84903 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube or 3.0 mL bone marrow (EDTA). Specimen must be received in the laboratory within 24 hours of collection due to liability of RNA. Minimum specimen: 1.0 mL whole blood or bone marrow. Notes: Order in cases of Philadelphia chromosome positive (Ph+) lymphoblastic leukemia to quantify the BCR-ABL1 p190 fusion form. For CML, use BCR-ABL Major (p210). Unacceptable: Serum or plasma. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed specimens. Frozen or clotted specimens. Transport temp: Refrigerated Method: Quantitative Reverse Transcription Polymerase Chain Reaction Unit code: 804903 CPT Code(s): 81207 Ref range: By report Reported: 5-7 days 10-93 Test List BBPL Directory of Services BCR-ABL, FISH Order code: 80491 Preferred specimen: 10.0 mL whole blood, green (sodium heparin) top tube or 2.0 mL bone marrow aspirate in a green (sodium heparin) top tube. Minimum specimen: 5.0 mL whole blood or 1.0 mL bone marrow Notes: Specimen must be received in laboratory within 24 hours of collection. Transport specimen on cold packs but do not place cold packs in direct contact with specimen. Other acceptable: Tissue (lymph nodes, spleen) in tissue media; Fluids 2-3 mL (ascitic, CSF) in sterile tube; Malignant fluids 50-100 mL in collection pouch; Fine Needle Aspirate in tissue media 10 pieces preferred (minimum of 2 pieces-0.2 cm3 in aggregrate); Formalin-fixed and paraffin-embedded tissue. Unacceptable: Clotted or frozen specimens. Paraffin-embedded tissue that has been decalcified. Transport temp: Refrigerated Method: Fluorescence in situ Hybridization (FISH) Unit code: 804901 CPT Code(s): 88367 (x3) Ref range: By report Reported: 5-10 days BCR-ABL, Major (p210) Qualitative by PCR Order code: 50100 Preferred specimen: 5.0 mL whole blood, lavender (EDTA), yellow (ACD solution A), light blue (sodium citrate), or green (sodium or lithium heparin) top tube. Refrigerate immediately after collection. Specimen should be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Testing includes pathologist's interpretation. Other acceptable: 3.0 mL bone marrow (EDTA) Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 550100 CPT Code(s): 81206, G0452 Ref range: By report Reported: 2-7 days Benadryl S1 0 See: Diphenhydramine Bence Jones Protein See: Protein Electrophoresis, Urine Benzene Quantitation, Whole Blood Order code: 84295 Preferred specimen: 2.0 mL whole blood, gray (potassium oxalate/sodium fluoride) or lavender (EDTA) top tube. Minimum specimen: 0.7 mL whole blood Unacceptable: Room temperature specimens. Transport temp: Refrigerated Method: Quantitative Gas Chromatography Unit code: 804295 CPT Code(s): 84600 Ref range: By report Reported: 3-6 days Benzodiazepine Confirmation, Quantitative, Urine Order code: 82914 Preferred specimen: 5 mL random urine in a clean plastic urine container. Minimum specimen: 7 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Test includes: Nordiazepam, Oxazepam, and OH-Alprazolam. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 812914 CPT Code(s): 80154 Ref range: By report Reported: 7-10 days Test List 10-94 BBPL Directory of Services Benzodiazepines, Serum or Plasma See: Drugs of Abuse Confirmation/Quantitation - Benzodiazepines, Serum or Plasma Benzol See: Benzene Quantitation, Whole Blood Benztropine Order code: 81120 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 0.4 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tubes or gels Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 804350 CPT Code(s): 80299 Ref range: By report Reported: 3-10 days Beryllium, Serum or Plasma Order code: 84370 Preferred specimen: 2.0 mL serum, royal blue (trace metal-free; no additive) top tube or red top tube. Remove serum from cells and transfer to a Trace Element-Free transport tube. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 2.0 mL plasma, royal blue (trace metal-free; EDTA) top tube. Remove plasma from cells and transfer to a Trace Element-Free transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Quantitative Inductively Coupled Plasma/Mass Spectrometry Unit code: 804370 S1 0 CPT Code(s): 83018 Ref range: By report Reported: 3-6 days Beta Streptococcus Culture, Genital See: Culture, Group B Screen Beta Streptococcus Culture, Throat See: Culture, Beta Strep,Throat Beta-2 Glycoprotein 1 Antibodies, IgG & IgM Order code: 80392 Preferred specimen: 2.0 mL serum, SST or red top tube. Minimum specimen: 1.0 mL serum Unacceptable: Plasma or other body fluids. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 803926 CPT Code(s): 86146 (x2) Ref range: Beta-2 Glycoprotein 1 Antibody, IgG Negative: 0-20 U Positive: 21 U or greater Beta-2 Glycoprotein 1 Antibody, IgM Negative: 0-20 U Positive: 21 U or greater Reported: 1-5 days 10-95 Test List BBPL Directory of Services Beta-2 Microglobulin Order code: 1231 Preferred specimen: 1.0 mL serum, red top tube or SST Minimum specimen: 0.3 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube Transport temp: Refrigerated Method: Nephelometry Unit code: 112350 CPT Code(s): 82232 Ref range: 1.2-2.5 mg/L Reported: 1-3 days Beta-2 Transferrin Order code: 80433 Preferred specimen: 2.0 mL serum, red top or gel-barrier tube, and 2.0 mL aural or nasal fluid in a sterile container without preservative. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Do not freeze specimens. Minimum specimen: 0.5 ml serum and 1.0 mL aural or nasal fluid. Unacceptable: Plasma or frozen specimens. Transport temp: Refrigerated Method: Qualitative Immunofixation Electrophoresis Unit code: 804380 CPT Code(s): 86334, 86335 Ref range: None detected Detection of a beta-2 transferrin band by IFE is diagnostic for the presence of cerebrospinal fluid (CSF). This test is useful in the differential diagnosis for CSF otorrhea or CSF rhinorrhea. Beta-2 transferrin is not detected by this methodology in normal serum, tears, saliva, sputum, nasal, or aural fluid. Reported: 1-4 days Beta-hCG, Qualitative, Pregnancy, Serum See: Human Chorionic Gonadotropin (Beta-hCG), Qualitative, Pregnancy, Serum Beta-hCG, Quantitative Tumor Marker Order code: 1378 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111018 CPT Code(s): 84702 Ref range: Male: 0-3 mIU/mL Female: 0-5 mIU/mL Reported: Within 24 hours Beta-hCG, Quantitative, Serum (Females) See: Human Chorionic Gonadotropin (Beta-hCG), Quantitative, Serum (Females) Beta-Hydroxybutyric Acid Order code: 80396 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow serum specimen to clot at room temperature, then remove serum from cells and transfer to a plastic transport tube and refrigerate. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells and transfer to a plastic transport tube and refrigerate. Transport temp: Refrigerated Method: Quantitative Enzymatic Unit code: 803965 CPT Code(s): 82010 Ref range: 0.0-3.0 mg/dL Reported: 1-3 days Betapace See: Sotalol Test List 10-96 S1 0 BBPL Directory of Services Bicarbonate (HCO3), Urine Order code: 80425 Preferred specimen: 4.0 mL aliquot from a random urine collection. Immediately upon collection, mix and remove aliquot into a plastic transport tube. Do not expose to air. Freeze urine aliquot. Minimum specimen: 0.3 mL urine Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Nonfrozen specimens Transport temp: CRITICAL FROZEN Method: Enzymatic Unit code: 804255 CPT Code(s): 82374 Ref range: Not defined Reported: 1-2 days Bile Acids, Fractionated & Total Order code: 81150 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Notes: Patient should be fasting a minimum of eight hours prior to specimen collection. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 804400 CPT Code(s): 83789 Ref range: 7 years and older: Cholic acid (CA) 0-1.9 µmol/L Chenodeoxycholic acid (CDC) 0-3.4 µmol/L Deoxycholic acid (DCA) 0-2.5 µmol/L Ursodeoxycholic acid (UDC) 0-1.0 µmol/L Total 0-7.0 µmol/L Reported: 1-6 days Bile Acids, Total Order code: 80440 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow specimen to clot completely at room temperature before separating from cells. Remove serum from cells and transfer to a plastic transport tube. S1 0 Minimum specimen: 0.5 mL serum Notes: Patient must be fasting a minimum of eight hours prior to collection. Unacceptable: Heparinized or hemolyzed specimens. Body fluids. Transport temp: Refrigerated Method: Enzymatic Unit code: 804405 CPT Code(s): 82239 Ref range: 0-10 µmol/L Reported: 1-2 days Bilirubin, Direct Order code: 1091 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Vanadate Oxidation Unit code: 101740 CPT Code(s): 82248 Ref range: 0-0.4 mg/dL Reported: Within 24 hours 10-97 Test List BBPL Directory of Services Bilirubin, Fractionated Order code: 1340 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Vanadate Oxidation Unit code: 101760 CPT Code(s): 82247, 82248 Ref range: Total: 0.2-1.2 mg/dL Direct: 0-0.4 mg/dL Indirect: 0.0-0.8 mg/dL Reported: Within 24 hours Bilirubin, Fractionated, Pediatric Order code: 1350 Preferred specimen: 0.2 mL serum, two full amber colored microtainer tubes with serum separator gel (gold top) or two full red top microtainers. If specimen will not be received in lab within 2 hours, centrifuge and remove serum from cells. Minimum specimen: 0.1 mL serum, one full microtainer tube. Notes: Protect specimen from light by using amber colored tubes or wrapping in foil. Transport temp: Refrigerated Method: Vanadate Oxidation Unit code: 103040 CPT Code(s): 82247, 82248 Ref range: Total: Age Up to 24 hours <5.0 mg/dL 24 to 48 hours <9.0 mg/dL 3-5 days <12.0 mg/dL >1 month 0.2-1.2 mg/dL Direct: 0-0.4 mg/dL Reported: Within 24 hours Bilirubin, Total Order code: 1090 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Vanadate Oxidation Unit code: 101730 CPT Code(s): 82247 Ref range: 0.2-1.2 mg/dL Reported: Within 24 hours Bilirubin, Total and Direct Order code: 1341 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Vanadate Oxidation Unit code: 101770 CPT Code(s): 82247, 82248 Ref range: Total: 0.2 - 1.2 mg/dL Direct: 0 - 0.4 mg/dL Reported: Within 24 hours Test List 10-98 S1 0 BBPL Directory of Services Bilirubin, Total, Pediatric Order code: 1351 Preferred specimen: 0.2 mL serum, two full amber colored microtainer tubes with serum separator gel (gold top) or two full red top microtainers. If specimen will not be received in lab within 2 hours, centrifuge and remove serum from cells. Minimum specimen: 0.1 mL serum, one full microtainer tube. Notes: Protect specimen from light by using amber colored tubes or wrapping in foil. Transport temp: Refrigerated Method: Vanadate Oxidation Unit code: 103030 CPT Code(s): 82247 Ref range: Age Up to 24 hours <5.0 mg/dL 24 to 48 hours <9.0 mg/dL 3-5 days <12.0 mg/dL >1 month 0.2-1.2 mg/dL Reported: Within 24 hours Bismuth, Blood Order code: 80455 Preferred specimen: 7.0 mL whole blood, royal blue (K EDTA) or (Na EDTA) top tube, in the original collection tube at room temperature or 2 refrigerated is also acceptable. 2 Minimum specimen: 1.0 mL whole blood Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na EDTA) tube. 2 Unacceptable: Heparin anticoagulant. Frozen specimens. Transport temp: Room temperature Method: Inductively Coupled Plasma/Mass Spectrophometry Unit code: 804551 CPT Code(s): 83018 Ref range: 0-5 µg/L Reported: 1-5 days S1 0 Bismuth, Urine Order code: 81175 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Specimen must be collected in a plastic container and refrigerated during collection period. Submit urine in two Trace Element-Free transport tubes. Do not use acid preservative. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician) prior to specimen collection. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies) or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrophometry Unit code: 804550 CPT Code(s): 83018 Ref range: Bismuth, Urine 0.0-2.0 µg/L Bismuth, Urine (24-hour) 0.0-3.0 µg/d Reported: 1-5 days 10-99 Test List BBPL Directory of Services BK Virus, Quantitative by PCR Order code: 80581 Preferred specimen: 1.0 mL serum, SST. Minimum specimen: 0.5 mL serum, plasma, whole blood, or urine. Notes: CRITICAL STERILE. Specimen source is required. Other acceptable: 1.0 mL plasma, lavender (EDTA). 1.0 mL whole blood, lavender or pink top tube. 1.0 mL random urine. Unacceptable: Heparinized or clotted specimens. Do not freeze whole blood specimens. Transport temp: Refrigerated Method: Quantitative Real-Time Polymerase Chain Reaction Unit code: 804581 CPT Code(s): 87799 Ref range: Not detected. The limit of quantification for this DNA assay is 2.6 log copies/mL (390 copies/mL). If the assay DID NOT DETECT the virus, the test result will be reported as "< 2.6 log copies/mL (< 390 copies/mL)." If the assay DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified." Reported: 1-5 days Bladder Tumor Associated Antigen (BTA) Order code: 1278 Preferred specimen: 2.0 mL voided urine or urine from a catheterized patient. Use a clean urine cup without preservatives or fixatives. Do not collect or store urine in paper or foam cups. Unacceptable: Urine collected or stored in paper or foam cups. Transport temp: Refrigerated Method: Qualitative Immunoassay Unit code: 804590 CPT Code(s): 86316 Ref range: Positive: Bladder tumor associated antigen detected. Negative: Bladder tumor associated antigen not detected. Reported: 1-5 days Bladder Tumor Detection Panel Order code: 35142 Preferred specimen: Fresh urine collected into a sterile specimen container. Immediately after collection, add 60 mL of the voided urine into a Urine Specimen Preservative container (contains 30 mL PreservCyt Solution). Secure the lid tightly and refrigerate ASAP. Urine preservative transport kits with handling instructions are available through BBPL Client Services. Minimum specimen: 60 mL urine Notes: Test includes: Urine Cytology, Urovysion, and p16. Other acceptable: Fresh urine (min: 60 mL) in a sterile specimen container mixed with urine cytology fixative (alcohol based-i.e. Cytorich). Add equal volume of fixative to urine (1:1 ratio). Urine must be fixed immediately after collection and refrigerated. Unacceptable: Urine specimens with no fixative added. Transport temp: Refrigerated Method: Fluorescence in situ Hybridization/Immunohistochemistry Unit code: 535142 CPT Code(s): 88112, 88120, 88342 Ref range: By report Reported: 2-7 days Blastomyces Antibodies by CF & ID Order code: 81180 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Minimum specimen: 0.25 mL serum Unacceptable: Severely lipemic or contaminated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion Unit code: 804600 CPT Code(s): 86612 (x2) Ref range: Blastomyces Antibody by CF: <1:8 Blastomyces Antibody by ID: None detected Reported: 2-4 days Blood Culture See: Culture, Blood Test List 10-100 S1 0 BBPL Directory of Services Blood Group and Rh Type See: ABO and Rh BMP See: Basic Metabolic Panel BNP See: B-Type Natriuretic Peptide Body Fluid Crystals See: Crystals, Body Fluid Body Fluid Culture See: Culture, Body Fluid Bone Specific Alkaline Phosphatase Order code: 80495 Preferred specimen: 0.5 mL serum, SST. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 0.5 mL plasma, green (sodium or lithium heparin) top tube. Unacceptable: Urine. Grossly hemolyzed specimens. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 804695 CPT Code(s): 84080 Ref range: Female: 6 months-2 years: 33.4-145.3 µg/L 3-6 years: 32.9-108.6 µg/L 7-9 years: 36.3-159.4 µg/L 10-12 years: 44.2-163.3 µg/L 13-15 years: 14.8-136.2 µg/L 16-17 years: 10.5-44.8 µg/L Premenopausal: 4.5-16.9 µg/L Postmenopausal: 7.0-22.4 µg/L S1 0 Male: 6 months-2 years: 31.6-122.6 µg/L 3-6 years: 31.3-103.4 µg/L 7-9 years: 48.6-140.4 µg/L 10-12 years: 48.8-155.5 µg/L 13-15 years: 27.8-210.9 µg/L 16-17 years: 15.3-126.8 µg/L 18-24 years: 10.0-28.8 µg/L 25 years and older: 6.5-20.1 µg/L Reported: 1-2 days Bordetella pertussis Antibodies, IgG, IgM, IgA Order code: 81205 Preferred specimen: 2.0 mL serum, red top or gel-barrier tube. Minimum specimen: 1.0 mL serum Unacceptable: Hemoysis, lipemia, or gross bacterial contamination. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbent Assay Unit code: 804700 CPT Code(s): 86615 (x3) Ref range: By report Reported: 2-8 days 10-101 Test List BBPL Directory of Services Bordetella pertussis DNA, Qualitative Real-Time PCR Order code: 39070 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction Unit code: 539070 CPT Code(s): 87798 Ref range: Negative Reported: 1-2 days Bordetella pertussis, Culture Order code: 81200 Preferred specimen: Collect two nasopharyngeal specimens using swabs provided in the Pertussis Collection Kit (available through Client Services). Place the first specimen swab in the Regan-Lowe semi-solid transport media and immerse the second specimen swab in the tube containing saline. Immerse the swabs completely in the media, cut off the excess shaft, and place the cap on securely. Leave the swabs immersed in the transport media and refrigerate immediately. Transport to the laboratory on cool packs within 24 hours of collection. Unacceptable: Inappropriate specimen transport device, cotton swabs, or frozen specimens. Transport temp: Refrigerated Method: Bacteriologic culture techniques Unit code: 804750 CPT Code(s): 99000 Ref range: Negative for Bordetella pertussis. Reported: Within 7 days Preliminary: As soon as positive detected Final: Negative at 7 days Bordetella pertussis/parapertussis by PCR Order code: 80475 Preferred specimen: Collect respiratory specimen; aspirate, bronchoalveolar lavage (BAL), sputum or swab. Transfer 2.0 mL fluid specimen to a sterile container or viral transport media. Place swabs in viral transport media. Viral transport media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Record specimen source on test request form. Minimum specimen: 0.5 mL respiratory specimens Notes: CDC recommended test for the diagnosis of pertussis. Unacceptable: Calcium-alginate swabs. Transport temp: Frozen Method: Qualitative Polymerase Chain Reaction Unit code: 804705 CPT Code(s): 87798 (x2) Ref range: By report Reported: 1-4 days Borrelia burgdorferi Antibodies, IgG & IgM Order code: 2600 Preferred specimen: 1.0 serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Unacceptable: Plasma, contaminated specimens or severely lipemic or hemolyzed specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay (ELISA) Unit code: 352001 CPT Code(s): 86618 Ref range: <0.91 LI Negative - Antibody to Borrelia burgdorferi not detected. 0.91-1.09 LI Equivocal - Suggest repeat testing in 2 weeks or testing with supplemental assay such as a Western Blot test. >1.09 LI Positive - Antibody to Borrelia burgdorferi detected. Reported: 1-4 days Test List 10-102 S1 0 BBPL Directory of Services Borrelia burgdorferi Antibodies, IgG & IgM by Western Blot Order code: 82512 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Per CDC guidelines, if ELISA test result is NEGATIVE, Western blot should not be performed. Unacceptable: CSF or plasma. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Western Blot Unit code: 825125 CPT Code(s): 86617 (x2) Ref range: Borrelia burgdorferi Antibody, IgG by Western Blot: Negative IgG: For this assay, a positive result is reported when any 5 or more of the following 10 bands are present: 18, 23, 28, 30, 39, 41, 45, 58, 66, or 93 kDa. All other banding patterns are reported as negative. Borrelia burgdorferi Antibody, IgM by Western Blot: Negative IgM: For this assay, a positive result is reported when any 2 or more of the following bands are present: 23, 39, or 41 kDa. All other banding patterns are reported as negative. Reported: 1-3 days Borrelia burgdorferi Antibodies, Total (CSF) Order code: 84051 Preferred specimen: 3.0 mL CSF. Minimum specimen: 0.5 mL CSF Unacceptable: Contaminated or heat-inactivated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 824950 CPT Code(s): 86618 Ref range: 0.99 LIV or less: Negative - Antibody to Borrelia burgdorferi not detected. 1.00-1.20 LIV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.21 LIV or greater: Positive - Probable presence of antibody to Borrelia burgdorferi detected. Reported: 1-3 days S1 0 Borrelia burgdorferi Antibodies, Total by ELISA with Reflex to IgG & IgM Western Blot Order code: 2602 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: If the ELISA result is >0.90, Western Blot will be added at an additional charge. Unacceptable: Plasma, severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Western Blot Unit code: 352002 CPT Code(s): 86618 Ref range: Borrelia burgdorferi Antibodies, Total by ELISA: <0.91 LI Negative - Antibody to Borrelia burgdorferi not detected. 0.91-1.09 LI Equivocal - Suggest repeat testing in 2 weeks or testing with supplemental assay such as a Western Blot test. >1.09 LI Positive - Antibody to Borrelia burgdorferi detected. Borrelia burgdorferi Antibody, IgG by Western Blot: Negative IgG Positive: Any five of the following 10 bands: 18, 23, 28, 30, 39, 41, 45, 58, 66, or 93 kDa. IgG Negative: Any pattern that does not meet the IgG-positive criteria. Borrelia burgdorferi Antibody, IgM by Western Blot: Negative IgM Positive: Any two of the following three bands: 23, 39, 41 kDa. IgM Negative: Any pattern that does not meet the IgM-positive criteria Reported: 1-4 days 10-103 Test List BBPL Directory of Services Borrelia Species by PCR Order code: 84875 Preferred specimen: 1.0 mL serum (SST) or EDTA plasma (lavender top tube). Remove serum or plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum, plasma, CSF, or synovial fluid. Notes: Specimen source is required. Other acceptable: 1.0 mL CSF or synovial fluid in a sterile container or tissue in a sterile container. Freeze immediately. Unacceptable: Heparinized specimens. Transport temp: Frozen Method: Polymerase Chain Reaction Unit code: 804875 CPT Code(s): 87476 Ref range: By report Reported: 1-4 days BRAF Mutation Analysis Order code: 32025 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block (0.2 cm³ piece of tissue) or 5 slides (7 micron thickness) from formalin-fixed paraffin block. Notes: If specimen is for Melanoma, please indicate on test request form. Testing includes pathologist's interpretation. Transport temp: Room temperature Method: Polymerase Chain Reaction (PCR) Unit code: 532025 CPT Code(s): 81210, 88381, G0452 Ref range: By report Reported: 5-7 days Breast Cancer Prognostic Profile Order code: 35601 Preferred specimen: Paraffin embedded breast tissue block. Please submit a copy of the pathology report. For multiple samples, submit a separate test request form with each sample. Notes: Test includes: DNA Cell Cycle Analysis, Paraffin Block (Breast) ERA/PRA Receptor Assay, Paraffin Block HER-2/neu Analysis S1 0 Transport temp: Room temperature Method: Image Analysis Immunohistochemistry and FISH Unit code: 535601 CPT Code(s): 88358, 88361 (x3), 88367 (x2) Ref range: By report Reported: Within 7 days Breast Carcinoma Associated Antigen See: CA 27.29 Bromide Order code: 81215 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Spectrophotometry Unit code: 805000 CPT Code(s): 80299 Ref range: Therapeutic Range: Sedation: 10-50 mg/dL (values > 50 mg/dL may be associated with mild toxicity) Epilepsy seizure control: 75-150 mg/dL (many patients will exhibit toxic symptoms within this range) > 150 mg/dL: May be associated with debilitating toxicity > 300 mg/dL: May be fatal Reported: 1-5 days Bronchial Washings Culture See: Culture, Lower Respiratory Tract Test List 10-104 BBPL Directory of Services Brucella Antibody (Total) by Agglutination Order code: 5190 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection. Minimum specimen: 0.2 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Please label specimens as "acute" or "convalescent". Unacceptable: Severely lipemic, hemolyzed, contaminated or heat in-activated specimens. Transport temp: Refrigerated Method: Bacterial Agglutination Unit code: 805051 CPT Code(s): 86622 Ref range: <1:20 Negative Reported: 2-4 days Brucella Antibody IgG, EIA Order code: 80552 Preferred specimen: 0.4 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Unacceptable: Hemolyzed, lipemic, or grossly contaminated specimens. Transport temp: Room temperature Method: Enzyme Immunoassay Unit code: 805052 CPT Code(s): 86622 Ref range: Negative Reported: 2-7 days Brucella Antibody IgM, EIA Order code: 80553 Preferred specimen: 0.4 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Unacceptable: Hemolyzed, lipemic, or grossly contaminated specimens. Transport temp: Room temperature S1 0 Method: Enzyme Immunoassay Unit code: 805053 CPT Code(s): 86622 Ref range: Negative Reported: 2-7 days Brufen See: Ibuprofen BTA See: Bladder Tumor Associated Antigen Bullous Pemphigoid Antigens (180 kDa & 230 kDa), IgG Order code: 80509 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Please submit Immunodermatology Required Clinical Information Form (Serum) with test request form and specimen. Unacceptable: Hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Enzyme Linked Immunosorbent Assay Unit code: 805090 CPT Code(s): 83516 (x2) Ref range: By report Reported: 3-11 days BUN See: Urea Nitrogen 10-105 Test List BBPL Directory of Services Bupropion Order code: 81216 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 1.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Non-frozen specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 805100 CPT Code(s): 80299 Ref range: Therapeutic Range: 50-100 ng/mL Toxic Level: Greater than 400 ng/mL The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Toxic concentrations may cause mental confusion, cardiac abnormalities and seizures. Concentrations below 25 ng/mL may have no effect. This method does not quantify the major metabolite, hydroxybupropion. Reported: 1-5 days Butabarbital Order code: 81230 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 1.0 mL serum or plasma Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Serum separator tubes. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry Unit code: 805150 CPT Code(s): 80299 Ref range: By report Reported: Within 10 days Butalbital Order code: 81232 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Gas Chromatography-Mass Spectrometry Unit code: 805200 CPT Code(s): 82205 Ref range: Therapeutic Range: 1-10 µg/mL Toxic: > 30 µg/mL Reported: 1-5 days C DIFF See: Clostridium difficile Toxin B by PCR C-Peptide Order code: 1352 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.2 mL serum Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 103500 CPT Code(s): 84681 Ref range: 1.1 - 4.6 ng/mL Reported: Within 24 hours Test List 10-106 S1 0 BBPL Directory of Services C-Reactive Protein Order code: 5070 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, green (lithium heparin) top tube. Transport temp: Refrigerated Method: Immunoturbidimetric Unit code: 350300 CPT Code(s): 86140 Ref range: 0-0.8 mg/dL Reported: Within 24 hours C-Reactive Protein, High Sensitivity Order code: 1422 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, green (lithium heparin) top tube. Transport temp: Refrigerated Method: Immunoturbidimetric Unit code: 114220 CPT Code(s): 86141 Ref range: By report Reported: Within 24 hours C-Telopeptide, Beta-Cross-Linked, Serum Order code: 80525 Preferred specimen: 1.0 mL serum, SST. Allow specimen to sit for 15-20 minutes at room temperature for proper clot formation. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum or plasma Notes: In patients receiving therapy with high biotin doses (i.e. >5 mg/day), no sample should be taken until at least 8 hours after the last biotin administration. Other acceptable: 1.0 mL plasma, pink (K EDTA) or green (sodium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube 2 and freeze. S1 0 Unacceptable: Hemolyzed specimens. Transport temp: Frozen Method: Electrochemiluminescent Immunoassay Unit code: 805255 CPT Code(s): 82523 Ref range: Female: 6 months-6 years: 500-1800 pg/mL 7-9 years: 566-1690 pg/mL 10-12 years: 503-2077 pg/mL 13-15 years: 160-1590 pg/mL 16-17 years: 167-933 pg/mL 18-29 years: 64-640 pg/mL 30-39 years: 60-650 pg/mL 40-49 years: 40-465 pg/mL Postmenopausal: 104-1008 pg/mL Male: 6 months-6 years: 500-1700 pg/mL 7-9 years: 522-1682 pg/mL 10-12 years: 553-2071 pg/mL 13-15 years: 485-2468 pg/mL 16-17 years: 276-1546 pg/mL 18-29 years: 87-1200 pg/mL 30-39 years: 70-780 pg/mL 40-49 years: 60-700 pg/mL 50-69 years: 40-840 pg/mL 70 years or greater: 52-847 pg/mL Reported: 1-4 days C1 Complement, Functional See: Complement C1, Functional 10-107 Test List BBPL Directory of Services C1 Esterase Inhibitor Functional Order code: 81250 Preferred specimen: 0.5 mL serum, SST. Minimum specimen: 0.1 mL serum or plasma Notes: Remove serum or plasma from cells ASAP, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 0.5 mL plasma, lavender (EDTA) or pink (K EDTA) top tube. 2 Unacceptable: Nonfrozen specimens Transport temp: CRITICAL FROZEN Method: Enzyme-Linked Immunosorbent Assay Unit code: 805450 CPT Code(s): 86161 Ref range: 68% or greater: Normal 41-67%: Indeterminate 40% or less: Abnormal Reported: 1-4 days C1 Esterase Inhibitor Panel Order code: 81270 Preferred specimen: 2.0 mL serum, SST. Remove serum from cells ASAP. Aliquot 1.0 mL serum into 2 separate transport tubes. Freeze one serum tube and transport frozen (CRITICAL FROZEN). Transport the other serum tube refrigerated. Minimum specimen: 0.4 mL frozen serum and 0.5 mL refrigerated serum. Notes: Test includes: C3 C4 C1 Esterase Inhibitor Total Transport temp: One frozen specimen and one refrigerated specimen. Method: Nephelometry Unit code: 805301 CPT Code(s): 86160 (x2), 86161 Ref range: C3: 88-201 mg/dL C4: 16-50 mg/dL C1 Esterase Inhibitor Total: 21-39 mg/dL Reported: 1-4 days C1 Esterase Inhibitor Total Order code: 85555 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze immediately. Minimum specimen: 0.4 mL serum Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Nephelometry Unit code: 805350 CPT Code(s): 86160 Ref range: 21-39 mg/dL Reported: 1-4 days C1Q Binding Immune Complex Detection See: Immune Complex C1Q C1Q Complement See: Complement C1Q C2 Complement See: Complement C2 C3 & C4 Complement See: Complement C3 & C4 C3 Complement See: Complement C3 Test List 10-108 S1 0 BBPL Directory of Services C4 Complement See: Complement C4 C5 Complement See: Complement C5 C6 Complement, Functional See: Complement C6, Functional C7 Complement, Functional See: Complement C7, Functional C8 Complement, Functional See: Complement C8, Functional C9 Complement, Functional See: Complement C9, Functional CA 125 See: Cancer Antigen 125 CA 15-3 See: Cancer Antigen-Breast (CA 15-3) S1 0 CA 19-9 See: Cancer Antigen-GI (CA 19-9) CA 27.29 See: Cancer Antigen 27.29 Cadmium, Blood Order code: 81283 Preferred specimen: 7.0 mL whole blood, royal blue (K2EDTA) or (Na2EDTA) top tube, in the original collection tube (preferred) at room temperature or refrigerated is also acceptable. Minimum specimen: 1.0 mL whole blood Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue Na EDTA tube. 2 Unacceptable: Heparin anticoagulant. Frozen specimens. Transport temp: Room temperature Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 805600 CPT Code(s): 82300 Ref range: 0.0-5.0 µg/L Reported: 1-3 days 10-109 Test List BBPL Directory of Services Cadmium, Urine Order code: 80561 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Specimen must be collected in a plastic container and refrigerated during the collection period. Submit urine in two Trace Element-Free transport tubes. Do not use acid preservative. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician) prior to specimen collection. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies) or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 805610 CPT Code(s): 82300 Ref range: Cadmium, Urine - per volume: 0.0-2.6 µg/L Cadmium, Urine - per 24-hour: 0.0-3.3 µg/d Cadmium, Urine - ratio to CRT: 0.0-3.0 µg/g crt Reported: 1-3 days Caffeine Order code: 81285 Preferred specimen: 0.5 mL serum, red top tube. Remove serum from cells within 6 hours of collection. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 0.5 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 6 hours of collection. Also acceptable (avoid if possible): Serum separator tube or plasma separator tubes stored at room temperature if removed from the gel within 6 hours or serum or plasma in a gel separator tube stored refrigerated if separated from the gel within 2 hours. Unacceptable: Citrated plasma or tubes that contain liquid anticoagulant. Transport temp: Refrigerated Method: Immunoassay Unit code: 805650 CPT Code(s): 80299 Ref range: Therapeutic Range: 6-20 µg/mL (neonates) Toxic: > 40 µg/mL S1 0 Reported: 1-5 days Calan See: Verapamil Calcitonin, Serum Order code: 81310 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.4 mL serum Notes: Patient should be fasting. Record on test request form if calcium infusion or pentagastrin injection tests are part of the patient preparation. Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy. Unacceptable: Lipemia, gross hemolysis, nonfrozen specimens or plasma. Transport temp: CRITICAL FROZEN Method: Immunochemiluminometric Assay Unit code: 805700 CPT Code(s): 82308 Ref range: Male: 0.0-8.4 pg/mL Female: 0.0-5.0 pg/mL Reported: 1-3 days Test List 10-110 BBPL Directory of Services Calcium, Ionized Order code: 1032 Preferred specimen: Collect one 5 mL serum gel-barrier tube. Centrifuge with stopper in place within 1 hour of collection. Do not open the tube or split the specimen. Do not expose the specimen to air during collection or transport process. Transport the original gel-barrier collection tube refrigerated. Do not freeze or ship on dry ice. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL serum Unacceptable: Plasma, specimens exposed to air, hemolyzed or frozen specimens. Transport temp: Refrigerated Method: Ion Selective Electrode Unit code: 103520 CPT Code(s): 82330 Ref range: 1.11-1.40 mmol/L Reported: Within 24 hours Calcium, Serum Order code: 1055 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Colorimetric Unit code: 101670 CPT Code(s): 82310 Ref range: 8.5-10.5 mg/dL Reported: Within 24 hours Calcium, Urine Order code: 1060 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Transport temp: Refrigerated S1 0 Method: Colorimetry Unit code: 102430 CPT Code(s): 82340 Ref range: Calcium Diet: Low to average 50-150 mg/day Average (800 mg/d) 100-300 mg/day Reported: Within 24 hours Calcium/Creatinine Ratio, Urine Order code: 1061 Preferred specimen: 5.0 mL random urine with no preservatives. Minimum specimen: 1.0 mL urine Transport temp: Refrigerated Method: Colorimetry/Kinetic Unit code: 102431 CPT Code(s): 82340, 82570 Ref range: <0.14 Reported: Within 24 hours Calculi (Urinary) Analysis See: Stone (Calculi) Analysis 10-111 Test List BBPL Directory of Services Calprotectin, Fecal Order code: 80583 Preferred specimen: 5 gm random stool in a clean unpreserved stool transport container. Minimum specimen: 1 gm of stool Unacceptable: Stool specimen in media or preservatives. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 805830 CPT Code(s): 83993 Ref range: 50 µg/g or less: Normal 51-120 µg/g: Borderline elevated, test should be re-evaluated in 4-6 weeks. 121 µg/g or greater: Abnormal, suggestive of inflammatory bowel disease (IBD). Reported: Within 5 days CALR (Calreticulin) Exon 9 Mutation Analysis by PCR Order code: 85840 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or 3.0 mL bone marrow (EDTA). Do not freeze. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: This mutation is helpful for the diagnosis and subclassification of myeloproliferative neoplasms in patients who lack JAK2 mutations. Unacceptable: Serum. Specimens collected in anticoagulants other than EDTA. Clotted or grossly hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Capillary Electrophoresis Unit code: 805840 CPT Code(s): 81479 Ref range: By report Reported: 2-7 days Campylobacter jejuni Antibody, IgG Order code: 80584 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Unacceptable: Hemolyzed, icteric, lipemic, contaminated, or heat-inactivated specimens. S1 0 Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 805845 CPT Code(s): 86625 Ref range: Less than 1:320 Negative - No significant level of Campylobacter jejuni IgG antibody detected. Greater than or equal to 1:320 Positive - IgG antibody to Campylobacter jejuni detected, suggestive of current or past infection. Reported: 2-8 days Campylobacter, Culture, Stool See: Culture, Stool with Shiga Toxin 1 and 2 by EIA Cancer Antigen 125 (Ovarian Cancer) Order code: 1273 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111045 CPT Code(s): 86304 Ref range: Less than 35 U/mL Reported: Within 24 hours Test List 10-112 BBPL Directory of Services Cancer Antigen 27.29 Order code: 1729 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and refrigerate. Freeze serum if specimen will not be received in laboratory within 48 hours of collection. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111049 CPT Code(s): 86300 Ref range: 0-38 U/mL Reported: Within 24 hours Cancer Antigen-Breast (CA 15-3) Order code: 81370 Preferred specimen: 1.0 mL serum, SST. Allow specimen to clot completely at room temperature. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Electrochemiluminescent Immunoassay The Roche Modular E170 CA 15-3 electrochemiluminescent immunoassay is used. Results obtained with different methods or kits cannot be used interchangeably. The CA 15-3 assay is used to aid in the management of Stage II and III breast cancer patients. Serial testing for patient CA 15-3 assay values should be used in conjunction with other clinical methods for monitoring breast cancer. Unit code: 805900 CPT Code(s): 86300 Ref range: 0-31 U/mL Reported: 1-3 days Cancer Antigen-GI (CA 19-9) Order code: 1249 Preferred specimen: 1.0 mL serum, SST. Allow specimen to clot completely at room temperature. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. S1 0 Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Body fluid, specimens collected in EDTA or sodium citrate. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 111040 CPT Code(s): 86301 Ref range: 0-37 U/mL Reported: 1-4 days Candida albicans Antibodies, IgG, IgM, IgA by ELISA Order code: 80592 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 805952 CPT Code(s): 86628 (x3) Ref range: By report Candida Antibody, IgG: 0.89 EV or less Negative - No significant level of detectable Candida albicans antibody. 0.90-0.99 EV Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful. 1.00 EV or greater Positive - Antibody to Candida albicans detected, which may indicate a current or past infection. Candida Antibody, IgM: 0.89 EV or less Negative - No significant level of detectable Candida albicans antibody. 0.90-0.99 EV Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful. 1.00 EV or greater Positive - Antibody to Candida albicans detected, which may indicate a current or past infection. Candida Antibody, IgA: 0.89 EV or less Negative - No significant level of detectable Candida albicans antibody. 0.90-0.99 EV Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful. 1.00 EV or greater Positive - Antibody to Candida albicans detected, which may indicate a current or past infection. The best evidence for current infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. Reported: 1-8 days 10-113 Test List BBPL Directory of Services Candida Antibody by Immunodiffusion Order code: 81335 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Unacceptable: Body fluids. Transport temp: Refrigerated Method: Qualitative Immunodiffusion Unit code: 805950 CPT Code(s): 86628 Ref range: None detected Reported: 2-5 days Candida Species Culture See: Fungal Culture Candida species DNA Probe Order code: 36010 Preferred specimen: Collect vaginal fluid specimen using BD Affirm VPIII Ambient Temperature Transport System. Specimens must be collected and transported in the manufacturer's test specific swab kits. BD Affirm VPIII Transport System is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Unacceptable: Swabs submitted in media other than BD Affirm VPIII Ambient Temperature Transport System. Transport temp: Room temperature Method: Nucleic Acid Probe Unit code: 536010 CPT Code(s): 87480 Ref range: Negative Reported: 1-3 days Cannabinoid Confirmation, Quantitative, Urine Order code: 81303 Preferred specimen: 15 mL random urine in a clean plastic urine container. Minimum specimen: 7 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 813103 CPT Code(s): 82542 Ref range: By report Reported: 2-3 days Cannabinoids (9-carboxy-THC), Serum or Plasma See: Drugs of Abuse Confirmation/Quantitation - Cannabinoids (9-carboxy-THC), Serum or Plasma Carbamazepine Epoxide & Total Order code: 80935 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Obtain trough specimen after steady-state is achieved (3-5 days). Draw within one hour prior to next dose. The epoxide half-life is 6-10 hours. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry/Quantitative EMIT Immunoassay Unit code: 813650 CPT Code(s): 80156, 80299 Ref range: Carbamazepine-10, 11 Epoxide: Therapeutic Range: Not well established Toxic Level: Greater than 15.0 µg/mL Total Carbamazepine: Therapeutic Range: 4.0-12.0 µg/mL Toxic Level: Greater than 20.0 µg/mL Reported: 1-5 days Test List 10-114 S1 0 BBPL Directory of Services Carbamazepine, Free & Total Order code: 85575 Preferred specimen: 2.0 mL serum, red top tube. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: Serum separator tube (avoid if possible) is acceptable if serum is remove from cells within 2 hours of collection. Unacceptable: Citrated plasma. Tubes that contain liquid anticoagulant. Transport temp: Refrigerated Method: Quantitative Enzyme Multiplied Immunoassay Technique Unit code: 838650 CPT Code(s): 80156, 80157 Ref range: Carbamazepine, Total: Therapeutic Range: 4.0-12.0 µg/mL Toxic Range: Greater than 20 µg/mL Free Carbamazepine: Therapeutic Range: 1.0-3.0 µg/mL Toxic Range: Greater than 3.8 µg/mL Percent Free Carbamazepine: 8.0-35.0% Reported: 1-5 days Carbamazepine, Total Order code: 1200 Preferred specimen: 0.5 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 0.5 mL plasma, green (sodium or lithium heparin) or lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 110010 CPT Code(s): 80156 S1 0 Ref range: Therapeutic: 4-10 µg/mL Potentially Toxic: >20.0 µg/mL Reported: Within 24 hours Carbidopa See: Sinemet Carbon Dioxide Order code: 1040 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes. Transport temp: Refrigerated Method: Enzymatic Unit code: 101650 CPT Code(s): 82374 Ref range: 20-32 mmol/L Reported: Within 24 hours Carbon Monoxide, Blood See: Carboxyhemoglobin, Blood 10-115 Test List BBPL Directory of Services Carboxyhemoglobin, Blood Order code: 81400 Preferred specimen: 7.0 mL whole blood, green (sodium or lithium heparin) top tube or lavender (EDTA) top tube. Refrigerate immediately after collection. Submit original full, unopened tube. Do not centrifuge or remove cap. Sampling time is end of shift (last two hours of exposure) for industrial exposure monitoring. Minimum specimen: 0.6 mL whole blood Unacceptable: Clotted specimens. Transport temp: Refrigerated Method: Co-oximetry Unit code: 806200 CPT Code(s): 82375 Ref range: Environmental exposure: nonsmoker: <2.0%, smoker: <9.0% Occupational exposure: BEI® (sampling time is end of shift): 3.5% Reported: 2-5 days Carcinoembryonic Antigen See: CEA Cardiolipin Antibodies, IgG, IgM Order code: 2076 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Unacceptable: Plasma and other body fluids. Hemolyzed, icteric, or lipemic specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 202706 CPT Code(s): 86147 (x2) Ref range: Cardiolipin Antibody, IgG: <10.0 GPL: Negative 10.0-11.9 GPL: Equivocal >or= 12.0 GPL: Positive Cardiolipin Antibody, IgM: <10.0 MPL: Negative 10.0-11.9 MPL: Equivocal >or= 12.0 MPL: Positive S1 0 Reported: 1-5 days Cardiolipin Antibodies, IgG, IgM, IgA Order code: 2027 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Unacceptable: Plasma and other body fluids. Hemolyzed, icteric, or lipemic specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 202705 CPT Code(s): 86147 (x3) Ref range: Cardiolipin Antibody, IgG: <10.0 GPL: Negative 10.0-11.9 GPL: Equivocal >or= 12.0 GPL: Positive Cardiolipin Antibody, IgM: <10.0 MPL: Negative 10.0-11.9 MPL: Equivocal >or= 12.0 MPL: Positive Cardiolipin Antibody, IgA: <8.0 APL: Negative 8.0-9.9 APL: Equivocal >or= 10.0 APL: Positive Reported: 1-5 days Test List 10-116 BBPL Directory of Services Cardiolipin Antibody, IgA Order code: 2072 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Unacceptable: Plasma. Bacterially contaminated specimens, grossly hemolyzed, icteric, or lipemic specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 202702 CPT Code(s): 86147 Ref range: <8.0 APL: Negative 8.0-9.9 APL: Equivocal >or= 10.0 APL: Positive Reported: 1-5 days Cardiolipin Antibody, IgG Order code: 2070 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Unacceptable: Plasma. Bacterially contaminated specimens, grossly hemolyzed, icteric, or lipemic specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 202700 CPT Code(s): 86147 Ref range: <10.0 GPL: Negative 10.0-11.9 GPL: Equivocal >or= 12.0 GPL: Positive Reported: 1-5 days Cardiolipin Antibody, IgM Order code: 2074 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Unacceptable: Plasma. Bacterially contaminated specimens, grossly hemolyzed, icteric, or lipemic specimens. S1 0 Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 202704 CPT Code(s): 86147 Ref range: <10.0 MPL: Negative 10.0-11.9 MPL: Equivocal >or= 12.0 MPL: Positive Reported: 1-5 days Carisoprodol & Meprobamate Order code: 86430 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Gas Chromatography/Mass Spectrometry Unit code: 806430 CPT Code(s): 80299, 83805 Ref range: Carisoprodol Less than 8 µg/mL Toxic: Greater than or equal to 8 µg/mL Meprobamate 5-20 µg/mL Toxic: > 40 µg/mL Reported: 1-4 days 10-117 Test List BBPL Directory of Services Carnitine, Free Order code: 80451 Preferred specimen: 0.5 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze ASAP. Minimum specimen: 0.2 mL plasma or serum Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 0.5 mL serum, red top tube. Unacceptable: Refrigerated or room temperature specimens. Avoid hemolysis. Transport temp: CRITICAL FROZEN Method: Tandem Mass Spectrophotometry Unit code: 806451 CPT Code(s): 83789 Ref range: 1-31 days: 15-55 µmol/L 32 days-12 months: 29-61 µmol/L 13 months-6 years: 25-55 µmol/L 7 years-20 years: 22-63 µmol/L 21 years or older: 25-60 µmol/L Reported: 1-4 days Carnitine, Total Order code: 81415 Preferred specimen: 0.5 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze ASAP. Minimum specimen: 0.2 mL plasma or serum Notes: Separate samples must be submitted when multiple tests are ordered. Other acceptable: 0.5 mL serum, red top tube. Unacceptable: Refrigerated or room temperature specimens. Avoid hemolysis. Transport temp: CRITICAL FROZEN Method: Tandem Mass Spectrometry Unit code: 806450 CPT Code(s): 83789 Ref range: 1-31 days: 21-83 µmol/L 32 days-12 months: 38-73 µmol/L 3 months-6 years: 35-90 µmol/L 7 years-20 years: 31-78 µmol/L 21 years or older: 34-86 µmol/L S1 0 Reported: 1-4 days Carotene, Total Order code: 81420 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells within 1 hour of collection, transfer to a plastic amber transport tube and freeze immediately. Protect from light during collection, storage, and shipping. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.6 mL serum Notes: Fasting specimen preferred. Unacceptable: Room temperature or refrigerated specimens. Icteric or hemolyzed specimens, and specimens not protected from light. Any specimen other than serum. Transport temp: Frozen Method: Spectrophotometry Unit code: 806500 CPT Code(s): 82380 Ref range: 60-200 µg/dL Reported: 1-3 days Cat Scratch Disease, Antibodies Panel See: Bartonella Henselae Catapres See: Clonidine Test List 10-118 BBPL Directory of Services Catecholamines Fractionated, Urine Free Order code: 81450 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. Record total volume and hours of collection on both the urine container and test request form. Patient should abstain from medications for 72 hours prior to collection. Minimum specimen: 2.5 mL aliquot from a well-mixed 24-hour or random urine collection. Notes: Refrigeration is the most important aspect of specimen preservation. Preservation can be enhanced by adjusting the pH to 2-3 by adding 6N HCL. Catecholamines are not stable above pH 7. A pH less than 2 can cause assay interference. Unacceptable: Specimens at room temperature. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 806650 CPT Code(s): 82384 Ref range: 18 years or older: Dopamine: 60-440 µg/d Epinephrine: 0-25 µg/d Norepinephrine: 0-100 µg/d Reported: 1-4 days Catecholamines, Fractionated, Plasma Order code: 81440 Preferred specimen: 4.0 mL plasma, green (sodium or lithium heparin) top tube. Collect on ice. Specimen should be centrifuged and plasma removed from cells and frozen within one hour after collection. Transport frozen plasma in a plastic transport tube. Minimum specimen: 2.1 mL frozen heparinized plasma Notes: Patient should be calm and in a supine position for 30 minutes prior to collection. Medications which may interfere with catecholamines and metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, carbidopa-levodopa (Sinemet®), clonidine, dexamethasone, diuretics (in doses sufficient to deplete sodium), ethanol, isoproterenol, labetalol, methyldopa (Aldomet®), MAO inhibitors, nicotine, nose drops, propafenone (Rythmol), reserpine, theophylline, tricyclic antidepressants, and vasodilators. The effects of drugs on catecholamine results may not be predictable. For optimum results, patient should be supine with venous catheter in place for 30 minutes prior to collection. "Upright" ranges typically show norepinephrine up to 700 pg/mL, epinephrine up to 900 pg/mL, and dopamine essentially unchanged. Children, particularly those under 2 years of age, often show an elevated catecholamine response to stress. Unacceptable: EDTA plasma, serum, or urine. Transport temp: Frozen S1 0 Method: High Performance Liquid Chromatography Unit code: 806600 CPT Code(s): 82384 Ref range: By report Reported: 1-4 days 10-119 Test List BBPL Directory of Services CBC with Automated Differential Order code: 2255 Preferred specimen: One 3-4 mL lavender (EDTA) top tube. If specimen will not be received in laboratory within 24 hours, send two unstained blood smears with EDTA tube. Refrigerate EDTA tube if specimen will not be received in laboratory within 24 hours of collection. Stability: Room temperature 24 hours, refrigerated 48 hours. Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Notes: Test includes: WBC, RBC, Hgb, Hct, MCV, MCH, MCHC, RDW, Platelet count, and Automated Differential. Other acceptable: If platelet clumping is a problem, submit both EDTA and sodium citrate (blue top) tubes. Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Refrigerated Method: Automated Hematology Analyzer Unit code: 94200 CPT Code(s): 85025 Ref range: ADULT: WBC RBC Hgb Hct MCV MCH MCHC RDW-CV Platelet Neut % Lymph % Mono % Eos % Baso % Neut Abs# Lymph Abs# Mono Abs# Eos Abs# Baso Abs # M/F 4.0-12.0 thou/cumm Male 3.8-5.8 mil/cumm Female 3.9-5.2 mil/cumm Male 12.0-18.0 gm/dL Female 11.5-16.0 gm/dL Male 37.0-53.0% Female 34.5-46.5% M/F 80-100 fL M/F 28.0-34.0 pg M/F 30.0-36.0 gm/dL M/F 11.3-14.7% M/F 130-400 thou/cumm M/F 39-79% M/F 16-50 % M/F 0-11% M/F 0-6.8% M/F 0-1.5% M/F 1.4-7.7 thou/cumm M/F 0.6-4.0 thou/cumm M/F 0-0.9 thou/cumm M/F 0-0.6 thou/cumm M/F 0-0.5 thou/cumm Reported: Within 24 hours CCND1 FISH S1 0 See: IGH/BCL-1 FISH Study CCP See: Cyclic Citrullinated Peptide Antibody, IgG CD20 - B Cells Order code: 35421 Preferred specimen: Whole Blood: 5.0 mL whole blood, lavender (EDTA) top tube and/or yellow (ACD solution A). Bone Marrow: 2.0 mL bone marrow submitted in a green top tube (sodium heparin). After specimen is well mixed with anticoagulant, add equal amount of RPMI to the tube and invert to mix. Label specimen as bone marrow. Tissue: Fresh tissue submitted in 10-15 mL RPMI. Specimens must be received within 48 hours of collection. Do not freeze specimens. Unacceptable: Fixed or frozen specimens. Transport temp: Refrigerated Method: Flow Cytometry Unit code: 535421 CPT Code(s): 88184, 88185 (x2), 88187 Ref range: By report Reported: 1-3 days CD4 See: Lymphocyte Subsets, T-Cell CD4/CD8 Lymphocyte Subsets, Immunodeficiency Panel Test List 10-120 BBPL Directory of Services CD56, Natural Killer Cell Assay Order code: 35456 Preferred specimen: 5 mL EDTA whole blood, lavender top tube or 5 mL whole blood from a green top tube (sodium heparin). Maintain specimen at room temperature. Do not freeze or refrigerate. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 2 mL whole blood Other acceptable: 5 mL ACD-A whole blood, yellow top tube, stable for 72 hours. Unacceptable: Hemolyzed, clotted, refrigerated or frozen specimens. Transport temp: Room temperature Method: Flow Cytometry Unit code: 535456 CPT Code(s): 86357 Reported: 3-5 days CDIFF See: Clostridium difficile Toxin B by PCR CEA Order code: 1275 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.5 mL Serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111050 CPT Code(s): 82378 Ref range: 0-3.0 ng/mL Reported: Within 24 hours CEBPA Mutation Detection Order code: 86685 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube or 3.0 mL bone marrow. S1 0 Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Testing includes pathologist's interpretation. Unacceptable: Serum or plasma. Frozen or clotted specimens. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Sequencing Unit code: 806685 CPT Code(s): 81403, G0452 Ref range: By report Reported: 12-14 days Celiac Disease Antibody Profile I Order code: 94604 Preferred specimen: 3.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 1.4 mL serum Notes: Test includes: Immunoglobulin A Gliadin Antibodies, IgA & IgG Tissue Transglutaminase Antibody, IgA with Reflex to Endomysial Antibody, IgA Titer Unacceptable: Plasma and other body fluids. Hemolyzed, icteric, grossly lipemic, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Indirect Fluorescent Antibody/Nephelometry Unit code: 94604 CPT Code(s): 82784, 83516 (x3) Ref range: See individual tests. Reported: 1-3 days 10-121 Test List BBPL Directory of Services Celiac Disease Antibody Profile II Order code: 94608 Preferred specimen: 2.5 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 1.3 mL serum Notes: Test includes: Immunoglobulin A Gliadin Antibody, IgG Tissue Transglutaminase Antibody, IgG Unacceptable: Plasma and other body fluids. Hemolyzed, icteric, grossly lipemic, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Nephelometry Unit code: 94608 CPT Code(s): 82784, 83516 (x2) Ref range: See individual tests. Reported: 1-3 days Celiac Disease Antibody Screen with Reflex Order code: 94607 Preferred specimen: 2.5 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 1.3 mL serum Notes: Test includes: Immunoglobulin A Gliadin Antibody, IgA Tissue Transglutaminase Antibody, IgA with Reflex to Endomysial Antibody, IgA Titer Unacceptable: Plasma and other body fluids. Hemolyzed, icteric, grossly lipemic, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Indirect Fluorescent Antibody/Nephelometry Unit code: 94607 CPT Code(s): 82784, 83516 (x2) Ref range: See individual tests. Reported: 1-3 days Celiac Disease Comprehensive Antibody Profile Order code: 94606 Preferred specimen: 4.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 2.0 mL serum Notes: Test includes: Immunoglobulin A, Serum Gliadin Antibodies, IgA & IgG Tissue Transglutaminase Antibody, IgG Tissue Transglutaminase Antibody, IgA with Reflex to Endomysial Antibody IgA Titer Unacceptable: Plasma or other body fluids. Hemolyzed, icteric, grossly lipemic, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Indirect Fluorescent Antibody/Nephelometry Unit code: 94606 CPT Code(s): 82784, 83516 (x4) Ref range: By report Reported: 2-5 days Cell Count and Differential, Body Fluid Order code: 2075 Preferred specimen: 1.0 mL body fluid in green (sodium heparin) top tube. Minimum specimen: 0.2 mL body fluid Notes: Indicate source on test request form and specimen container. Other acceptable: 1.0 mL body fluid in lavender (EDTA) top tube. Unacceptable: Frozen specimens. Transport temp: Refrigerated. Transport to lab same day as collected. DO NOT FREEZE. Method: Microscopic examination Unit code: 201500 CPT Code(s): 89051 Ref range: WBC: 10-200 cumm RBC: 0-10 cumm Segs: 0-25% Monos: 75-100% Reported: Within 24 hours Test List 10-122 S1 0 BBPL Directory of Services Cell Count and Differential, CSF Order code: 2720 Preferred specimen: 0.5 mL CSF is sterile screw top container. Minimum specimen: 0.2 mL CSF Notes: Deliver to laboratory ASAP, refrigerated. Do not freeze. Generally performed on tube #3 or #4 of the collection. Unacceptable: Frozen specimens. Counts on clotted specimens may be inaccurate. Transport temp: Refrigerated Method: Hemocytometer/Microscopic Unit code: 201700 CPT Code(s): 89051 Ref range: WBC: 0-10 cu mm RBC: 0 cu mm Segs: 0% Monos: 0% Reported: Within 24 hours Celontin See: Methsuximide & Normethsuximide Centromere Antibody Order code: 5130 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Grossly hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody (IFA) Unit code: 350130 CPT Code(s): 86039 Ref range: <1:80 Reported: 1-3 days S1 0 Centromere IgG See: Centromere Antibody Cerebral Spinal Fluid Culture See: Culture, CSF Cerebral Spinal Fluid, Cell Count & Differential See: Cell Count & Differential, CSF Cerebral Spinal Fluid, Glucose See: Glucose, CSF Cerebral Spinal Fluid, IgG Synthesis & Index See: CSF Protein Analysis Cerebral Spinal Fluid, Protein, Total See: Protein, Total, CSF Certican See: Everolimus 10-123 Test List BBPL Directory of Services Ceruloplasmin Order code: 81470 Preferred specimen: 1.0 mL serum, SST. Minimum specimen: 0.1 mL serum or plasma Notes: Remove serum or plasma from cells within 45 minutes of collection and transfer to a plastic transport tube. Other acceptable: 1.0 mL plasma, green (lithium heparin) top tube. Unacceptable: Hemolyzed specimens. Transport temp: Refrigerated Method: Immunologic Unit code: 806800 CPT Code(s): 82390 Ref range: Male: 16.2-35.6 mg/dL Female: 17.9-53.3 mg/dL Reported: 1-3 days CH50 Complement See: Complement Total, CH50 CHIC2, 4q12 Deletion (FIP1L1 and PDGFRA Fusion), FISH Order code: 86840 Preferred specimen: Submit only one of the following specimens: 10.0 mL whole blood, green (sodium heparin) top tube. Invert tube several times to mix blood. or 2.0 mL bone marrow green (sodium heparin) top tube. Invert tube several times to mix bone marrow. Please submit a Cytogenetics Hematologic Disorders Request form with the specimen. Forms are available through BBPL Client Services. Minimum specimen: 2.0 mL whole blood or 1.0 mL bone marrow Unacceptable: Clotted blood or bone marrow. Anticoagulants other than sodium heparin (green top) are not recommended and are harmful to the viability of the cells. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 806840 CPT Code(s): 88271 (x3), 88275 (x2), 88291 S1 0 Ref range: By report Reported: Within 8 days Chlamydia Antibody Panel, IgG & IgM by IFA Order code: 81525 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Please mark specimens plainly as "acute" or "convalescent." Unacceptable: Hyperlipemic, hemolyzed, or contaminated serum. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 806850 CPT Code(s): 86631 (x3), 86632 (x3) Ref range: < 1:64 C. pneumoniae IgG < 1:64 C. psittaci IgG < 1:64 C. trachomatis IgG < 1:20 C. pneumoniae IgM < 1:20 C. psittaci IgM < 1:20 C. trachomatis IgM Reported: 1-4 days Test List 10-124 BBPL Directory of Services Chlamydia Antibody Panel, IgG by IFA Order code: 81510 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Unacceptable: Hyperlipemic, hemolyzed, or contaminated sera. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 807150 CPT Code(s): 86631 Ref range: < 1:64 C. trachomatis IgG. < 1:64 C. pneumoniae IgG. < 1:64 C. psittaci IgG. Reported: 1-3 days Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel Order code: 3520 Preferred specimen: APTIMA® vaginal swab, APTIMA® unisex swab (for endocervical and male urethral specimens), APTIMA® urine tube, or PreservCyt (ThinPrep) liquid Pap specimen, transport at room temperature or refrigerated. Aptima® swabs and Aptima® urine tubes may be frozen at -20°C to -70°C. Directions for specimen collection and handling are provided on the APTIMA® collection kits. APTIMA® kits are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Minimum specimen: One APTIMA® swab or tube. 1.0 mL ThinPrep or SurePath liquid media, neat urine, or viral transport media. Notes: Specimen Stability: APTIMA® swab specimens: 60 days at room temperature or refrigerated, 12 months frozen (-20°C to -70°C). Urine specimen in APTIMA® tube: 30 days at room temperature or refrigerated, 12 months frozen (-20°C to -70°C). Neat urine in collection cup: 24 hours at room temperature or refrigerated. Pap media specimen: Preservcyt, 30 days at room temperature or refrigerated; SurePath, 29 days at room temperature or refrigerated. Viral transport media: 2 days at room temperature, 3 days refrigerated. Other acceptable: SurePath liquid Pap specimen, endocervical/urethral swab in viral transport media or neat urine in sterile urine cup. Unacceptable: Probetec specimens, swabs in saline, specimens not within defined limits of stability. Transport temp: Room temperature Method: Nucleic Acid Amplification Test (NAAT) Unit code: 95540 CPT Code(s): 87491, 87591 S1 0 Ref range: Negative Reported: 2-5 days Chlamydia trachomatis Culture Order code: 81495 Preferred specimen: Cervical, urethral, rectal, eye swab or peritoneal fluid immediately preserved in Chlamydia (UTM) Universal Transport media (available through BBPL Client Services). Transport frozen on dry ice. Do not transport in PCR media (probetec or digene media) or bacterial gel-based media. Notes: Source of specimen is preferred. Other acceptable: Also acceptable for newborns: nasopharyngeal aspirate/washing/swab immediately preserved in Chlamydia transport media. Unacceptable: Urine. Specimens not preserved in Chlamydia culture transport media. Dry swabs, wood swabs, and calcium alginate swabs. Transport temp: Frozen Method: Cell Culture/Immunofluorescence Unit code: 807051 CPT Code(s): 87110, 87140 Ref range: Culture negative for Chlamydia trachomatis. Reported: 2-3 days 10-125 Test List BBPL Directory of Services Chlamydia trachomatis DNA Order code: 3380 Preferred specimen: APTIMA® vaginal swab, APTIMA® unisex swab (for endocervical and male urethral specimens), APTIMA® urine tube, or PreservCyt (ThinPrep) liquid Pap specimen, transport at room temperature or refrigerated. Aptima® swabs and Aptima® urine tubes may be frozen at -20°C to -70°C. Directions for specimen collection and handling are provided on the APTIMA® collection kits. APTIMA® kits are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Minimum specimen: One APTIMA® swab or tube. 1.0 mL ThinPrep or SurePath,1.0 mL viral transport media, or 2.0 mL neat urine. Notes: Specimen Stability: APTIMA® swab specimens: 60 days at room temperature or refrigerated, 12 months frozen (-20°C to -70°C). Urine specimen in APTIMA® tube: 30 days at room temperature or refrigerated, 12 months frozen (-20°C to -70°C). Neat urine in collection cup: 24 hours at room temperature or refrigerated. Pap media specimen: Preservcyt, 30 days at room temperature or refrigerated; SurePath, 29 days at room temperature or refrigerated. Viral transport media: 2 days at room temperature, 3 days refrigerated. Other acceptable: SurePath liquid Pap specimen, endocervical/urethral swab in viral transport media or neat urine in sterile urine cup. Unacceptable: Probetec specimens, swabs in saline, specimens not within defined limits of stability. Transport temp: Room temperature Method: Nucleic Acid Amplification Test (NAAT) Unit code: 536001 CPT Code(s): 87491 Ref range: Negative Reported: 2-5 days Chloracol See: Chloramphenicol Chloramphenicol Order code: 81530 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated S1 0 Method: High Performance Liquid Chromatography Unit code: 807300 CPT Code(s): 82415 Ref range: Therapeutic peak: 10-25 µg/mL Toxic: >25 µg/mL Reported: 1-5 days Chlordiazepoxide See: Librium & Nordiazepam Chloride, Fecal Order code: 81551 Preferred specimen: 5 gm aliquot of liquid random stool in a clean unpreserved stool transport container. Minimum specimen: 1 gm liquid stool Notes: Stool must be liquid. Do not add saline or water to liquefy sample. Unacceptable: Formed or viscous stool. Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 807400 CPT Code(s): 82438 Ref range: Not established Reported: 2-3 days Test List 10-126 BBPL Directory of Services Chloride, Fluid Order code: 80745 Preferred specimen: 1.0 mL body fluid (includes CSF) Minimum specimen: 0.2 mL body fluid Notes: Indicate source on test request form. Unacceptable: Breast milk and salivary fluid. Speimens containing sodium fluoride/potassium oxalate as anticoagulants. Contaminated or hemolyzed specimens. Specimens too viscous to be aspirated by instrument. Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 807452 CPT Code(s): 82438 Ref range: None established Reported: Within 24 hours Chloride, Serum Order code: 1035 Preferred specimen: 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 101640 CPT Code(s): 82435 Ref range: 98-110 mmol/L Reported: Within 24 hours Chloride, Urine Order code: 1053 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Transport temp: Refrigerated S1 0 Method: Ion-Selective Electrode Unit code: 102468 CPT Code(s): 82436 Ref range: 110-250 mmol/day Reported: Within 24 hours Chlorinated Pesticides Order code: 80747 Preferred specimen: 5.0 mL serum, red top tube. DO NOT collect in SST. Minimum specimen: 2.1 mL serum or plasma Other acceptable: 5.0 mL plasma, green (sodium or lithium heparin) top tube. Unacceptable: Gel tubes or gray (sodium fluoride) top tube. Transport temp: Room temperature Method: Chromatography Unit code: 807475 CPT Code(s): 82441 Ref range: By report Reported: 3-8 days 10-127 Test List BBPL Directory of Services Chlorpromazine Order code: 85650 Preferred specimen: 2.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Minimum specimen: 1.0 mL serum or plasma Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection. Also acceptable (avoid if possible): Serum separator tube or plasma separator tubes stored at room temperature if removed from the gel within 6 hours or serum or plasma in a gel separator tube stored refrigerated if removed from the gel within 2 hours. Unacceptable: Whole blood. Light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 839250 CPT Code(s): 84022 Ref range: Adult (12 years and older): Therapeutic Range: 50-300 ng/mL Toxic Level: Greater than 750 ng/mL Child (0-11 years): Therapeutic Range: 30-80 ng/mL Toxic Level: Greater than 200 ng/mL Reported: 1-5 days Cholesterol, Fluid Order code: 1318 Preferred specimen: 1.0 mL body fluid in a plastic transport tube. Minimum specimen: 0.5 mL fluid Notes: Indicate source on test request form. Transport temp: Refrigerated Method: Enzymatic Unit code: 103178 CPT Code(s): 84311 Ref range: None established Reported: Within 24 hours Cholesterol, LDL, Direct S1 0 See: LDL Cholesterol, Direct Serum Cholesterol, LDL, Low Density Lipoprotein See: Lipid Profile Cholesterol, Total Order code: 1095 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Enzymatic Unit code: 101780 CPT Code(s): 82465 Ref range: < 200 mg/dL Reported: Within 24 hours Cholinesterase, Dibucaine Inhibition See: Pseudocholinesterase, Dibucaine Inhibition Cholinesterase, RBC/Hgb Ratio Order code: 81570 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) top tube. Do not freeze or place cells directly on cool packs when shipping. Minimum specimen: 1.0 mL whole blood Unacceptable: Frozen, clotted, or hemolyzed specimens. Specimens collected in green top tubes (sodium or lithium heparin). Transport temp: Refrigerated Method: Enzymatic Unit code: 807700 CPT Code(s): 82482 Ref range: 25-52 U/g Hb Reported: 1-4 days Test List 10-128 BBPL Directory of Services Cholinesterase, Serum Order code: 1385 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Transport temp: Refrigerated Method: Kinetic Unit code: 103060 CPT Code(s): 82480 Ref range: 4900-11900 U/L Reported: Within 24 hours Chorionic Gonadotropin, (Beta-hCG) Quantitative, Serum (Females) See: Human Chorionic Gonadotropin, (B-hCG) Quantitative Chromatin Antibody, IgG Order code: 80755 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.15 mL serum Unacceptable: Urine or plasma. Contaminated, heat-inactivated, severely hemolyzed, icteric, or lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 807755 CPT Code(s): 83516 Ref range: Negative: 19 Units or less Moderate Positive: 20-60 Units Strong Positive: 61 Units or greater Reported: 1-8 days Chromium, Serum S1 0 Order code: 81600 Preferred specimen: 2.0 mL serum, royal blue (no additive) top tube. Remove serum from cells and transfer to a Trace Element-Free transport tube ASAP. Do not allow serum to remain on cells. Minimum specimen: 0.5 mL serum Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free tubes may be due to contamination. Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive). Unacceptable: Separator tubes or gels or specimens that are not separated from the red cells or clot within 6 hours. Transport temp: Room temperature Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 808150 CPT Code(s): 82495 Ref range: Less than or equal to 5.0 µg/L Reported: 1-4 days Chromium, Urine Order code: 80812 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Specimen must be collected in a plastic container and should be refrigerated during collection period. Submit urine in two Trace Element-Free Transport Tubes. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies) or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 808152 CPT Code(s): 82495 Ref range: Chromium, Urine - per volume: 0.0-5.0 µg/L Chromium, Urine - 24-hour: 0.0-6.0 µg/d Chromium, Urine - ratio to CRT: No reference interval (µg/g crt) Reported: 1-5 days 10-129 Test List BBPL Directory of Services Chromogranin A Order code: 80770 Preferred specimen: 0.2 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum or plasma Notes: No radioisotopes should be administered to the patient within 48 hours prior to venipuncture. Other acceptable: 0.2 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Grossly hemolyzed specimens, non-EDTA or nonheparinzed plasma. Radioactive isotopes administered within 48 hours prior to venipuncture. Transport temp: Refrigerated Method: Radioimmunoassay (RIA) Unit code: 807760 CPT Code(s): 86316 Ref range: 0-5 nmol/L Reported: 2-6 days Chromosome Analysis, Adult ALL Panel by FISH See: Acute Lymphocytic Leukemia (ALL) Panel by FISH, Adult Chromosome Analysis, Aggressive Lymphoma Panel by FISH See: Lymphoma (Aggressive) Panel by FISH Chromosome Analysis, Amniotic Fluid Order code: 81617 Preferred specimen: 30.0 mL amniotic fluid in a sterile container. Do not refrigerate or freeze. TIME SENSITIVE. Specimen must be received in the laboratory within 24 hours of collection. Minimum specimen: 15.0 mL amniotic fluid Notes: Please submit Patient History for Prenatal Cytogenetics form. The information on this form is required to perform prenatal cytogenetic testing. Complete the form and submit with the test request form and specimen. Include clinical indication. Unacceptable: Frozen or bloody specimens. Transport temp: Room temperature Method: Giemsa-Band Analysis S1 0 Unit code: 807800 CPT Code(s): 88235, 88269, 88291 Ref range: By report Reported: 7-14 days Chromosome Analysis, Blood Order code: 81615 Preferred specimen: 5.0 mL whole blood, green (sodium heparin) top tube. Do not freeze or expose to extreme temperatures. TIME SENSITIVE. Specimen must be received in the laboratory within 24 hours of collection. Minimum specimen: 2.0 mL whole blood Notes: Order this test when assessing congenital abnormalities. Please submit a Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) studies. Complete the form and submit with the test request form and specimen. Include clinical indication. Unacceptable: Frozen or clotted specimens. Transport temp: Room temperature Method: Giemsa-Band Analysis Unit code: 807950 CPT Code(s): 88230, 88262, 88291 Ref range: By report Reported: 3-10 days Test List 10-130 BBPL Directory of Services Chromosome Analysis, Blood, with Reflex to Genomic Microarray Order code: 87951 Preferred specimen: 5.0 mL whole blood, green (sodium heparin) top tube. Do not freeze or expose to extreme temperatures. TIME SENSITIVE. Specimen must be received in the laboratory within 24 hours of collection. Minimum specimen: 2.0 mL whole blood Notes: Please submit a Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) studies. Complete the form and submit with the test request form and specimen. Include clinical indication. When the result of Chromosome Analysis is "normal," then Genomic Microarray testing will be added at an additional charge. Unacceptable: Frozen or clotted specimens. Transport temp: Room temperature Method: Giemsa Band/Genomic Microarray (Oligo-SNP Array) Unit code: 807951 CPT Code(s): 88230, 88262, 88291 Ref range: By report Reported: 10-18 days Chromosome Analysis, Bone Marrow Order code: 80915 Preferred specimen: Collect non-diluted bone marrow aspirate in a heparinized syringe. Transfer 3.0 mL bone marrow to a green (sodium heparin) top tube. Do not freeze or expose to extreme temperatures. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 0.5 mL bone marrow Notes: Although bone marrow is the recommended sample type for hematological disorder studies, blood can be substituted if bone marrow cannot be obtained. Refer to Chromosome Analysis, Leukemic Blood (order code 81616). Unacceptable: Frozen or clotted specimens. Transport temp: Room temperature Method: Giemsa-Band Analysis Unit code: 807915 CPT Code(s): 88237, 88264, 88291 Ref range: By report Reported: 3-10 days S1 0 Chromosome Analysis, Chronic Lymphocytic Leukemia (CLL) Panel by FISH Order code: 80794 Preferred specimen: 10.0 mL whole blood, green (sodium heparin) top tube or 2.0 mL bone marrow aspirate in a green (sodium heparin) top tube. Minimum specimen: 5.0 mL whole blood or 1.0 mL bone marrow Notes: Specimen must be received in laboratory within 24 hours of collection. Other acceptable: Tissue (lymph nodes, spleen) in tissue media; Fluids 2-3 mL (ascitic, CSF) in sterile tube with equal volume of RPMI media; Malignant fluids 50-100 mL in collection pouch; or Fine Needle Aspirate in tissue media 10 pieces preferred (minimum of 2 pieces0.2 cm³ in aggregrate). Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Refrigerated Method: Fluorescence in situ Hybridization (FISH) Unit code: 807924 CPT Code(s): 88367 (x9) Ref range: By report Reported: Varies Chromosome Analysis, FISH-Interphase Order code: 80722 Preferred specimen: 5.0 mL whole blood, green (sodium heparin) top tube or 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred to a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 2.0 mL whole blood or 1.0 mL bone marrow Notes: Please submit Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) testing. Complete the form and submit with the test request form and specimen. Record the names of the probes needed for testing on the test request form. A Molecular Cytogenetics (FISH) Probe menu is available through BBPL Client Services. Other acceptable: Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807922 CPT Code(s): 88271, 88275, 88291 Ref range: By report Reported: 3-10 days 10-131 Test List BBPL Directory of Services Chromosome Analysis, FISH-Metaphase Order code: 80723 Preferred specimen: 5.0 mL whole blood, green (sodium heparin) top tube or 3.0 mL bone marrow transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 2.0 mL whole blood or 1.0 mL bone marrow Notes: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. If FISH only is requested, please submit a copy of previous cytogenetics report. Please submit Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) testing. Complete the form and submit with the test request form and specimen. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807923 CPT Code(s): 88271, 88273, 88291 Ref range: By report Reported: 3-10 days Chromosome Analysis, Fragile X See: Fragile X (FMR1) Diagnostic Chromosome Analysis, Leukemia Blood Order code: 81616 Preferred specimen: 5.0 mL whole blood, green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 0.5 mL whole blood Unacceptable: Frozen or clotted specimens. Transport temp: Room temperature Method: Giemsa-Band Analysis Unit code: 808000 CPT Code(s): 88237, 88264, 88291 Ref range: By report Reported: 3-10 days S1 0 Chromosome Analysis, Lymph Node See: Chromosome Analysis, Oncology Chromosome Analysis, MDS Panel by FISH See: Myelodysplastic Syndrome (MDS) Panel by FISH Chromosome Analysis, Multiple Myeloma Panel by FISH See: Multiple Myeloma Panel by FISH Chromosome Analysis, Oncology Order code: 80910 Preferred specimen: 10 mm biopsy tissue in a sterile, screw-top container filled with tissue transport medium at room temperature or any specimen type for oncology studies other than peripheral blood, bone marrow, and solid tumors. Thaw media prior to tissue inoculation. Tissue culture transport media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers. Do not place tissue in formalin. Do not freeze specimen. Notes: TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Other acceptable: Pleural or other body fluid: 5.0 mL in a green (sodium heparin) top tube at room temperature. Transport fluid in original collection tube. Unacceptable: Frozen specimens. Tissue submitted in formalin. Transport temp: Room temperature Method: Giemsa-Band Analysis Unit code: 807910 CPT Code(s): 88237, 88264, 88291 Ref range: By report Reported: 3-10 days Test List 10-132 BBPL Directory of Services Chromosome Analysis, Prenatal FISH Order code: 80785 Preferred specimen: 30.0 mL amniotic fluid in a sterile conical plastic screw top tube. Do not refrigerate or freeze. TIME SENSITIVE. Specimen must be received in the laboratory within 24 hours of collection. Minimum specimen: 15.0 mL amniotic fluid Notes: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. Please submit Patient History for Prenatal Cytogenetics form. The information on this form is required to perform prenatal cytogenetic testing. Complete the form and submit with the test request form and specimen. Counseling and informed consent are recommended for genetic testing. Cytogenetic Testing consent forms are available through BBPL Client Services. Fluorescence in situ hybridization (FISH) is performed for aneuploidy of chromosomes X, Y, 13, 18, and 21. Unacceptable: Frozen or bloody specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807805 CPT Code(s): 88271 (x5), 88275 (x5), 88291 Ref range: By report Reported: 1-3 days Chromosome Analysis, Products of Conception Order code: 80781 Preferred specimen: Products of conception (minimum 5 mg) in a sterile, screw-top container filled with tissue transport medium at room temperature. Thaw media prior to tissue inoculation. Tissue culture transport media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. If cytogentics tissue media is not available, collect in plain RPMI, Hanks solution, sterile saline, or ringers. If autopsy is ordered, facia lata, diaphragm, tendon, skin, tissue from internal organs (if fresh), chest wall cartilage (particularly if macerated) or placenta from fetal side should be submitted; if no autopsy is performed, placenta from fetal side is preferred (e.g. villi). Umbilical cord or achiles tendon is also acceptable. Do not place products of conception in formalin or freeze the specimen. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Notes: Please submit Patient History for Prenatal Cytogenetics form. The information on this form is required to perform prenatal cytogenetic testing. Complete the form and submit with the test request form and specimen. If specimen collection time is greater than 72 hours, testing may be compromised. Every attempt will be made to culture the specimen. Unacceptable: Frozen specimens. Intact fetus. Specimens preserved in formalin. Specimens consisting of maternal tissue (decidua) only. Autolyzed or contaminated specimens. Transport temp: Room temperature Method: Giemsa-Band Analysis Unit code: 807810 CPT Code(s): 88233, 88262, 88291 Ref range: By report S1 0 Reported: Varies Chromosome Analysis, Skin Biopsy Order code: 80905 Preferred specimen: 4 mm skin biopsy in a sterile, screw-top container filled with tissue transport medium at room temperature. Thaw media prior to tissue inoculation. Tissue culture transport media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers. Do not place tissue in formalin. Do not freeze specimen. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Notes: Please submit Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) testing. Complete the form and submit with the test request form and specimen. Unacceptable: Frozen specimens. Specimens preserved in formalin. Transport temp: Room temperature Method: Giemsa-Band Analysis Unit code: 807905 CPT Code(s): 88233, 88262, 88291 Ref range: Normal male: 46, XY Normal female: 46, XX Reported: Varies Chromosome Analysis, Solid Tumor Order code: 81590 Preferred specimen: 10 mm solid tumor biopsy in a sterile, screw-top container filled with tissue transport medium at room temperature. Thaw media prior to tissue inoculation. Tissue culture transport media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers. Do not place tissue in formalin. Do not freeze specimen. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 5 mm solid tumor biopsy Unacceptable: Frozen specimens. Specimens preserved in formalin. Transport temp: Room temperature Method: Giemsa-Band Analysis Unit code: 807900 CPT Code(s): 88239, 88264, 88291 Ref range: By report Reported: Varies 10-133 Test List BBPL Directory of Services Chronic Urticaria Index Order code: 80816 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL serum Notes: Patients taking calcineurin inhibitors should stop their medication for 72 hours prior to draw. Patients taking prednisone should be off their medication for 2 weeks prior to draw. Unacceptable: Specimens other than serum. Contaminated, grossly hemolyzed, or lipemic specimens. Transport temp: CRITICAL FROZEN Method: Semi-Quantitative Ex Vivo Challenge/Cell Culture/Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 808165 CPT Code(s): 86352 Ref range: 10 Units or less A value of greater than 10 Units suggests the presence of basophil stimulating autoantibodies. Reported: 2-6 days Chylomicron Screen, Body Fluid Order code: 80833 Preferred specimen: 1.0 mL body fluid in a plastic transport tube. Do not freeze. Minimum specimen: 0.2 mL body fluid Notes: Indicate source on test request form. Unacceptable: Frozen specimens. Plasma, serum or whole blood. Transport temp: Refrigerated Method: Electrophoresis Unit code: 808330 CPT Code(s): 82664 Ref range: Absent Reported: 1-8 days Citrate, Urine Order code: 81650 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random collection. Refrigerate 24-hour specimen during collection. Adjust pH to less than or equal to 2 by adding 6M HCL. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 0.5 mL urine aliquot Other acceptable: Specimens previously preserved with boric acid. Transport temp: Refrigerated Method: Enzymatic Unit code: 808350 CPT Code(s): 82507 Ref range: 18 years and older: 320-1240 mg/d Reference interval for random urine has not been established. Reported: Within 24 hours Citric Acid, Urine See: Citrate, Urine CK Isoenzymes See: Creatine Kinase (CK) Isoenzymes CK Total See: CPK, Creatine Kinase CK Total & MB See: Creatine Kinase, Total & MB Test List 10-134 S1 0 BBPL Directory of Services Clomipramine & Metabolite Order code: 82505 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Do not collect in SST. Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 808460 CPT Code(s): 80299 Ref range: Therapeutic Range: Total clomipramine and norclomipramine: 220-500 ng/mL Toxic: > 900 ng/mL Reported: 1-5 days Clonazepam Order code: 81660 Preferred specimen: 4.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 1.1 mL serum or plasma Notes: Collect specimen immediately prior to next dose unless specified otherwise. Other acceptable: 4.0 mL plasma, green (sodium or lithium heparin) or lavender (EDTA) top tube. Remove plasma from cells ASAP. Unacceptable: Separator tubes or gels Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 808400 CPT Code(s): 80154 Ref range: Therapeutic: 15-60 ng/mL Reported: 1-3 days S1 0 Clonidine Order code: 81655 Preferred specimen: 2.0 mL serum, red top tube. Do not draw in SST tube. Minimum specimen: 0.7 mL serum or plasma Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tubes. Transport temp: Refrigerated Method: High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 808450 CPT Code(s): 80299 Ref range: By report Reported: Varies Clorazepate (Tranxene) Order code: 85800 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 0.4 mL serum or plasma Notes: Remove serum or plasma from cells ASAP. Specimen should be collected prior to next dose unless otherwise noted. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Separator tubes or gels Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 840250 CPT Code(s): 80154 Ref range: Therapeutic: 0.5-2.0 µg/mL (reported as nordiazepam) Reported: 1-4 days 10-135 Test List BBPL Directory of Services Clostridium difficile Toxin by PCR Order code: 53810 Preferred specimen: Fresh, unpreserved, liquid or soft stool specimen in a dry, sterile screw-top container. Minimum specimen: 0.5 mL liquid stool or 1 g soft stool. Other acceptable: Stool placed in Cary Blair transport media. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to Cary Blair medium using sterile swab or applicator, adding up to the fill line on the Cary Blair vial label. Mix vial well. Frozen raw stool is acceptable but results will be reported with a disclaimer. Unacceptable: Dried formed stool or stool in formalin or preservative other than Cary Blair. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction (PCR) Unit code: 538100 CPT Code(s): 87493 Ref range: Not Detected Reported: 1-2 days Clozapine (Clozaril) Order code: 88475 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 0.3 mL serum or plasma Notes: Remove serum or plasma from cells ASAP and transfer to a plastic transport tube. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Serum separator tubes or gels. Transport temp: Refrigerated Method: High-Pressure Liquid Chromatography/Tandem Mass Spectrometry Unit code: 808475 CPT Code(s): 80159 Ref range: Therapeutic: average steady-state serum concentrations following 100 mg twice daily: Peak (2.5 hours after last dose): 102-771 ng/mL Trough (just before dose): 41-343 ng/mL Reported: 1-3 days S1 0 CMP See: Comprehensive Metabolic Panel CMV See: Culture, Cytomegalovirus Cytomegalovirus, Qualitative PCR Cytomegalovirus, Quantitative PCR Cytomegalovirus Antibody, IgG Cytomegalovirus Antibody, IgM Cytomegalovirus Antibody, IgG & IgM CO, Blood See: Carbon Monoxide, Blood CO2 See: Carbon Dioxide Test List 10-136 BBPL Directory of Services Cobalt, Blood Order code: 80970 Preferred specimen: 7.0 mL whole blood, royal blue (K EDTA or Na EDTA) top tube, in the original collection tube at room temperature or refrigerated 2 2 is also acceptable. Minimum specimen: 0.5 mL whole blood Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na EDTA) tube. 2 Unacceptable: Heparin anticoagulant. Frozen specimens. Transport temp: Room temperature Method: Quantitative Inductively Coupled Plasma-Mass Spectrometry Unit code: 809730 CPT Code(s): 83018 Ref range: 0.5-3.9 µg/L Reported: 1-5 days Cobalt, Serum or Plasma Order code: 80973 Preferred specimen: 2.0 mL serum, royal blue (no additive) top tube. Remove serum from cells ASAP and transfer to a Trace Element-Free transport tube. Do not allow serum to remain on cells. Minimum specimen: 0.5 mL serum or plasma Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free tubes may be due to contamination. Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive). Other acceptable: 2.0 mL plasma, royal blue (EDTA) top tube. Remove plasma from cells ASAP and transfer to a Trace Element-Free transport tube. Do not allow plasma to remain on cells. Unacceptable: Separator tubes or gels and specimens that are not separated from the red cells, or clot, within 6 hours. Transport temp: Room temperature Method: Quantitative Inductively Coupled Plasma-Mass Spectrometry Unit code: 809731 S1 0 CPT Code(s): 83018 Ref range: Less than or equal to 1.0 µg/L Serum or plasma cobalt testing is intended to detect potentially toxic exposure and is the preferred method for evaluating metal ion release from metal-on-metal joint arthroplasty. Reported: 1-5 days Cocaine & Metabolites, Serum or Plasma See: Drugs of Abuse Confirmation/Quantitation - Cocaine & Metabolites, Serum or Plasma Cocaine Confirmation, Quantitative, Urine Order code: 82918 Preferred specimen: 15 mL random urine in a clean plastic urine container. Minimum specimen: 7 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Test includes: Cocaine Metabolite and Benzoylecgonine. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 812918 CPT Code(s): 82520 Ref range: By report Reported: 2-3 days 10-137 Test List BBPL Directory of Services Coccidioides Antibodies, IgG & IgM Order code: 81740 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Minimum specimen: 0.15 mL serum or CSF Other acceptable: 2.0 mL CSF Unacceptable: Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Semi-Quanitative Enzyme-Linked Immunosorbent Assay Unit code: 809800 CPT Code(s): 86635 (x2) Ref range: Coccidioides Ab, IgG: 0.9 IV or less: Negative - No significant level of Coccidioides IgG antibody detected. 1.0-1.4 IV: Equivocal - Questionable presence of Coccidioides IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1.5 IV or greater: Positive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection. Coccidioides Ab, IgM: 0.9 IV or less: Negative - No significant level of Coccidioides IgM antibody detected. 1.0-1.4 IV: Equivocal - Questionable presence of Coccidioides IgM antibody detected. Repeat testing in 10-14 days may be helpful. 1.5 IV or greater: Positive - Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection. Reported: 1-5 days Codeine See: Drug Confirmation, Quantitation Opiates, Serum or Plasma Coenzyme Q10, Total Order code: 89860 Preferred specimen: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Collect blood in chilled green top tube. Immediately centrifuge specimen. Remove plasma from cells within 45 minutes of collection, transfer to a plastic amber transport tube and freeze. Protect from light during collection, storage, and shipment. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL plasma Unacceptable: Use of EDTA anticoagulant. Specimens not protected from light. Plasma not frozen within 24 hours of collection. Transport temp: Frozen S1 0 Method: High-Pressure Liquid Chromatography (HPLC) with Electrochemical Detection Unit code: 809860 CPT Code(s): 82491 Ref range: 0.37-2.20 µg/mL Reported: 3-5 days Cogentin See: Benztropine Cold Agglutinins Order code: 80994 Preferred specimen: 1.0 mL serum, red top tube or SST. Keep vacutainer tube in warm water (37ºC) until serum is removed from cells. Refrigeration of specimen before separation of serum from cells will adversely affect test results. Minimum specimen: 0.5 mL serum Unacceptable: Refrigerated whole blood. Plasma or CSF. Severely hemolyzed, lipemic, or contaminated specimens. Transport temp: Refrigerated Method: Hemagglutination Unit code: 809940 CPT Code(s): 86157 Ref range: < 1:32 Negative Reported: 2-5 days Collagen C Telopeptide See: C-Telopeptide, Beta-Cross-Linked, Serum Test List 10-138 BBPL Directory of Services Collagen Cross Linked N-Telopeptide (NTx), Urine Order code: 82884 Preferred specimen: 1.0 mL urine aliquot from a well-mixed second morning void or 24-hour collection. Refrigerate 24-hour specimen during collection. Collect without preservative. Freeze aliquot in a plastic transport tube. Minimum specimen: 0.5 mL urine aliquot Notes: For monitoring therapy, a baseline sample should be collected prior to initiation of therapy. Subsequent samples for comparison should be collected at the same time of day as the baseline sample. Unacceptable: Samples contaminated with blood or having extensive hemolysis. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 828840 CPT Code(s): 82523 Ref range: By report Reported: 1-4 days Complement Activity, Total, CH50 Order code: 81810 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST or gel barrier tubes. Allow blood to clot for one hour at room temperature. Remove serum from cells ASAP or within 2 hours of collection. Transfer serum to a plastic transport tube and freeze. Minimum specimen: 0.3 mL serum Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Specimens left to clot at 2-8 C. Specimens exposed to repeated freeze/thaw cycles. Nonfrozen specimens. Separator tubes. Transport temp: CRITICAL FROZEN Method: Enzyme-Linked Immunosorbent Assay Unit code: 810200 CPT Code(s): 86162 Ref range: 60-144 CAE Units Reported: 1-4 days Complement C1, Functional S1 0 Order code: 81048 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Allow blood to clot at room temperature for 20-60 minutes. Remove serum from cells, transfer to a plastic transport tube and freeze on dry ice or at -70ºC within 2 hours. Minimum specimen: 0.25 mL serum Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Plasma. Thawed specimens. Separator tubes or gels. Transport temp: CRITICAL FROZEN Method: Hemolytic Assay Unit code: 810048 CPT Code(s): 86161 Ref range: By report Reported: 28-31 days Complement C1Q Order code: 81620 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.1 mL plasma Notes: Separate samples must be submitted when multiple tests are ordered. Unacceptable: Grossly hemolyzed, hyperlipemic, or room temperature specimens. Serum or non-EDTA plasma. Transport temp: CRITICAL FROZEN Method: Radial Immunodiffusion Unit code: 809950 CPT Code(s): 86160 Ref range: 109-242 µg/mL For the C1q Binding assay, refer to order code 81280. The C1q Binding assay detects circulating immune complexes. The Complement Component 1q Level assay quantifies the active fraction component, C1q, of the C1 complement protein complex. Reported: 5-10 days 10-139 Test List BBPL Directory of Services Complement C2 Order code: 81770 Preferred specimen: 1.0 mL serum, SST. Allow to clot for one hour at room temperature. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.3 mL serum Notes: Separate specimens must be submitted when multiple tests are ordered. Plasma specimens are not recommended. Unacceptable: Specimens left to clot at 2-8 C. Specimens subjected to repeated freeze/thaw cycles. Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Radial Immunodiffusion Unit code: 810050 CPT Code(s): 86160 Ref range: 1.0-4.0 mg/dL Reported: 5-10 days Complement C3 Order code: 1395 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens. Transport temp: Refrigerated Method: Nephelometry Unit code: 112400 CPT Code(s): 86160 Ref range: 88-201 mg/dL Reported: 1-2 days Complement C3 & C4 Order code: 1401 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens. Transport temp: Refrigerated S1 0 Method: Nephelometry Unit code: 112430 CPT Code(s): 86160 (x2) Ref range: C3: 88-201 mg/dL C4: 16-50 mg/dL Reported: 1-2 days Complement C4 Order code: 1400 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens. Transport temp: Refrigerated Method: Nephelometry Unit code: 112410 CPT Code(s): 86160 Ref range: 16-50 mg/dL Reported: 1-2 days Complement C5 Order code: 81790 Preferred specimen: 1.0 mL serum, SST. Allow blood to clot for one hour at room temperature. Remove serum from cells wtihiin 2 hours after collection, transfer to a plastic transport tube and freeze immediately. Minimum specimen: 0.3 mL serum Notes: Separate specimens must be submitted when multiple tests are ordered. Plasma samples are not recommended. Unacceptable: Specimens left to clot at refrigerated temperature. Specimens subjected to repeated freeze/thaw cycles. Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Radial Immunodiffusion Unit code: 810150 CPT Code(s): 86160 Ref range: 7-20 mg/dL Reported: 3-8 days Test List 10-140 BBPL Directory of Services Complement C6, Functional Order code: 80155 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Allow blood to clot at room temperature for 20-60 minutes. Remove serum from cells, transfer to a plastic transport tube and freeze on dry ice or at -70ºC within 2 hours of draw. Minimum specimen: 1.0 mL serum Notes: Separate specimens must be submitted when multiple test are ordered. Unacceptable: Separator tubes or gels. Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Hemolytic Assay Unit code: 810155 CPT Code(s): 86161 Ref range: By report Reported: 28-31 days Complement C7, Functional Order code: 81160 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Allow blood to clot at room temperature for 20-60 minutes. Remove serum from cells, transfer to a plastic transport tube and freeze on dry ice or at -70ºC within 2 hours of draw. Minimum specimen: 1.0 mL serum Notes: Separate specimens must be submitted when multiple test are ordered. Unacceptable: Separator tubes or gels. Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Hemolytic Assay Unit code: 810160 CPT Code(s): 86161 Ref range: By report Reported: 28-31 days Complement C8, Functional Order code: 81016 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Allow blood to clot at room temperature for 20-60 minutes. Remove serum from cells, transfer to a plastic transport tube and freeze on dry ice or at -70ºC within 2 hours of draw. S1 0 Minimum specimen: 1.0 mL serum Notes: Separate specimens must be submitted when multiple test are ordered. Unacceptable: Separator tubes or gels. Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Hemolytic Assay Unit code: 810165 CPT Code(s): 86161 Ref range: By report Reported: 28-31 days Complement C9, Functional Order code: 81017 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Allow blood to clot at room temperature for 20-60 minutes. Remove serum from cells, transfer to a plastic transport tube and freeze on dry ice or at -70ºC within 2 hours of draw. Minimum specimen: 1.0 mL serum Notes: Separate specimens must be submitted when multiple test are ordered. Unacceptable: Separator tubes or gels. Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Hemolytic Assay Unit code: 810170 CPT Code(s): 86161 Ref range: By report Reported: 28-31 days Complete Blood Count See: CBC with Automated Differential 10-141 Test List BBPL Directory of Services Complete HNPP Evaluation Order code: 81229 Preferred specimen: 20.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 20.0 mL whole blood Notes: Test includes PMP22 DNA Sequencing and PMP22 Duplication/Deletion DNA. Complete the patient billing information on the test request form and include a photo copy (front and back) of all relevant insurance cards. Unacceptable: Frozen specimens. Transport temp: Room temperature Method: Multiplex Ligation-dependent Probe Amplification, Polymerase ChainReaction (PCR) and DNA Sequencing Unit code: 810229 Ref range: No duplications/deletions detected, no sequence variation detected. Reported: 16-23 days Compound S See: 11-Deoxycortisol Quantitative Comprehensive Metabolic Panel Order code: 1128 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Notes: Test includes: Albumin Alkaline Phosphatase BUN Calcium Carbon Dioxide Chloride Creatinine Glucose Sodium Potassium SGOT (AST) SGPT (ALT) Total Bilirubin Total Protein Glomerular Filtration Rate S1 0 Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: See individual tests Unit code: 90128 CPT Code(s): 80053 Ref range: Albumin Alkaline Phosphatase BUN Calcium Carbon Dioxide Chloride Creatinine Glucose Potassium SGOT (AST) SGPT (ALT) Sodium Total Bilirubin Total Protein 3.0-5.5 g/dL 30-140 U/L 10-26 mg/dL 8.5-10.5 mg/dL 20-32 mmol/L 98-110 mmol/L 0.4-1.5 mg/dL 70-99 mg/dL 3.5-5.0 mmol/L 0-41 U/L 0-45 U/L 136-145 mmol/L 0.2-1.2 mg/dL 6.0-8.5 g/dL Reported: Within 24 hours Connexin 26 (GJB2), Sequencing Order code: 81024 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Notes: Diagnostic testing for GJB2-related nonsyndromic hearing loss. Carrier screening for GJB2-related nonsyndromic hearing loss. Please submit a Patient History for Hearing Loss form. The information on this form is required to perform hearing loss testing. Complete the form and submit with the test request form and specimen. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Sequencing Unit code: 810240 CPT Code(s): 81252 Reported: Within 21 days Test List 10-142 BBPL Directory of Services Connexin 30 (GJB6) 2 Deletions Order code: 81242 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Notes: Diagnostic testing for GJB6-related nonsyndromic hearing loss. Carrier screening for GJB6-related nonsyndromic hearing loss. Mutations Tested: 309kb del(GJB6-D13S1830), previously reported as 342kb, and 232kb del(GJB6-D13S1854). Please submit Patient History for Hearing Loss form. The information on this form is required to perform hearing loss testing. Complete the form and submit with the test request form and specimen. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Capillary Gel Electrophoresis Unit code: 810242 CPT Code(s): 81254 Ref range: By report Reported: 2-7 days Coombs-Direct Order code: 5050 Preferred specimen: One 7 mL lavender (EDTA) top tube. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 4.0 mL whole blood, lavender (EDTA) top tube Notes: Specimen should be labeled with patient name, date of birth, social security number and collection date. Transport temp: Refrigerated Method: Hemagglutination Unit code: 300400 CPT Code(s): 86880 Ref range: Negative Reported: 1-2 days Copper, Serum or Plasma Order code: 81820 Preferred specimen: 2.0 mL serum, royal blue (no additive) top tube. Remove serum from cells ASAP and transfer to a Trace Element-Free transport tube. Do not allow serum to remain on cells. Minimum specimen: 0.5 mL serum or plasma S1 0 Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free tubes may be due to contamination. Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive). Other acceptable: 2.0 mL plasma, royal blue (EDTA) top tube. Remove plasma from cells ASAP and transfer to a Trace Element-Free transport tube. Do not allow plasma to remain on cells. Unacceptable: Separator tubes or gels and specimens that are not separated from the red cells, or clot, within 6 hours. Transport temp: Room temperature Method: Quantitative Inductively Coupled Plasma/Mass Spectrometry Unit code: 810300 CPT Code(s): 82525 Ref range: 0 -10 years: Male: 75-153 µg/dL Female: 75-153 µg/dL 11 years-12 years: Male: 64-132 µg/dL Female: 64-132 µg/dL 13 years-18 years: Male: 57-129 µg/dL Female: 57-129 µg/dL 19 years and older : Male: 70-140 µg/dL Female: 80-155 µg/dL Reported: 1-2 days 10-143 Test List BBPL Directory of Services Copper, Urine Order code: 81830 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour collection or random urine. Specimen must be collected in a plastic container and should be refrigerated during collection. Submit urine in two Trace Element-Free transport tubes. Do not add acid preservative. Record total volume and collection time on both the sample container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician) prior to specimen collection. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 810350 CPT Code(s): 82525 Ref range: Copper, Urine 0.2-8.0 µg/dL Copper, Urine (24-hour) 3-50 µg/d Reported: 1-3 days Cordarone See: Amiodorone & Metabolite Corneal Culture See: Culture, Eye Cortisol Stimulation Test (Response to ACTH) Order code: 1236 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Draw baseline specimen prior to ACTH injection. ACTH injection to be administered by physician. Draw blood 30 and 60 minutes after injection. Label tubes clearly with collection times. S1 0 Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111071 CPT Code(s): 82533 (x3) Ref range: By report Reported: Within 24 hours Cortisol Urine Free Order code: 81840 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random collection. Refrigerate 24-hour specimen during collection period. Do not add acid or preservatives. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Unacceptable: Room temperature specimens. Acidified specimens or specimens with preservatives. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 810450 CPT Code(s): 82530 Ref range: Cortisol, Urine Free - per 24h (µg/24h): Male: 3-8 years: Less than or equal to 18 µg/24h 9-12 years: Less than or equal to 37 µg/24h 13-17 years: Less than or equal to 56 µg/24h 18 years and older: Less than or equal to 60 µg/24h Female: 3-8 years: Less than or equal to 18 µg/24h 9-12 years: Less than or equal to 37 µg/24h 13-17 years: Less than or equal to 56 µg/24h 18 years and older: Less than or equal to 45 µg/24h Cortisol, Urine Free - ratio to CRT (µg/g CRT): Male: Prepubertal: Less than 25 µg/g CRT 18 years and older: Less than 32 µg/g CRT Female: Prepubertal: Less than 25 µg/g CRT 18 years and older: Less than 24 µg/g CRT Pregnancy: Less than 59 µg/g CRT Reported: 1-4 days Test List 10-144 BBPL Directory of Services Cortisol, Free Order code: 81449 Preferred specimen: 1.0 mL serum, red top tube or SST. Centrifuge and remove serum from cells within 2 hours of collection. Transfer serum to a plastic transport tube and freeze. Minimum specimen: 0.6 mL serum or plasma Notes: Please label specimen plainly as a.m. or p.m. collection. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Grossly hemolyzed or heparinized specimens. Transport temp: Frozen Method: Equilibrium Dialysis/Electrochemiluminescent Immunoassay Unit code: 810449 CPT Code(s): 82530 Ref range: 8-10 a.m. collection: 0.31-1.19 µg/dL 4-6 p.m. collection: 0.15-0.94 µg/dL Reported: 1-5 days Cortisol, Saliva Order code: 81044 Preferred specimen: Collect saliva using a plain cotton swab. Swab must be completely saturated to ensure sufficient volume for testing. Transfer saturated swab to the plain (non-citric acid) cotton Salivette collection device. Follow the collection instructions provided with the Salivette collection device. Record the time of collection on the test request form and on the Salivette transport container. Salivette collection device is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Do not collect specimen within 60 minutes after eating a meal, within 12 hours after consuming alcohol, immediately after brushing teeth or after any activity that may cause gums to bleed. Rinse mouth thoroughly with water 10 minutes before specimen collection. Recommended collection time is between 11:00 p.m. and 1:00 a.m. Notes: Bovine hormones normally present in dairy products can cross-react with anti-cortisol antibodies and cause false results. Acidic or high sugar foods can compromise assay performance by lowering sample pH and influencing bacterial growth. Samples with pH values greater than 9.0 or less than 3.5 must be recollected. Unacceptable: Specimens not collected using the Salivette® collection device. Specimens visibly contaminated with blood, mucus, food particles or cellular debris. Sodium azide preservative. Specimens with pH values greater than 9.0 or less than 3.5 must be recollected. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 810448 CPT Code(s): 82533 Ref range: By report For a collection at 2300 hr, the normal cortisol concentration is less than 0.112 µg/dL. Patients with Cushing's Syndrome have concentrations of 0.112 µg/dL or greater. S1 0 Reported: 1-4 days Cortisol, Serum Order code: 1234 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111070 CPT Code(s): 82533 Ref range: AM Cortisol: 6-29 µg/dL PM Cortisol: 3-17 µg/dL Reported: Within 24 hours Cotinine Screen, Serum or Plasma Order code: 81091 Preferred specimen: 3.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hour of collection and transport to a plastic transport tube. Minimum specimen: 1.0 mL serum or plasma Notes: For medical purposes only; not valid for forensic use. Other acceptable: 3.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Immunoassay (IA) Unit code: 810491 CPT Code(s): 80101 Ref range: By report Reported: 5-7 days 10-145 Test List BBPL Directory of Services Cotinine Screen, Urine CRL COC Order code: 81049 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 810490 CPT Code(s): 83887 Reported: 1-5 days Coxiella burnetii (Q-Fever) Antibodies, IgG & IgM with Reflex to Titer Order code: 83702 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Notes: If Coxiella burnetii IgG and/or IgM antibodies are detected, then a titer will be added at an additional charge. Transport temp: Refrigerated Method: Immunofluorescence Assay Unit code: 833702 CPT Code(s): 86638 (x4) Ref range: By report Reported: 3-7 days Coxiella burnetii (Q-Fever) Antibody IgG, Phase I & II by IFA Order code: 85020 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Acute and convalescent specimens should be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" and "convalescent". Unacceptable: Severely lipemic, hemolyzed, or contaminated specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody S1 0 Unit code: 833700 CPT Code(s): 86638 (x2) Ref range: Phase I: < 1:16 No antibody detected. Phase II: < 1:16 No antibody detected. Reported: 1-5 days Coxsackie A9 Virus Antibodies by CF Order code: 81850 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.25 mL serum Notes: Acute and convalescent specimens should be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Unacceptable: Severely lipemic, hemolyzed, or contaminated specimens. Transport temp: Refrigerated Method: Complement Fixation Unit code: 810500 CPT Code(s): 86658 Ref range: <1:8 Reported: 2-5 days Test List 10-146 BBPL Directory of Services Coxsackie B Virus Antibodies Order code: 81860 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or CSF Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Please mark specimens plainly as "acute" or "convalescent". Other acceptable: 1.0 mL CSF Unacceptable: Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Serum Neutralization Unit code: 810550 CPT Code(s): 86658 (x6) Ref range: Coxsackie B1: Less than 1:10 Coxsackie B2: Less than 1:10 Coxsackie B3: Less than 1:10 Coxsackie B4: Less than 1:10 Coxsackie B5: Less than 1:10 Coxsackie B6: Less than 1:10 Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection. Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection. Reported: 6-9 days CPK Isoenzymes See: Creatine Kinase (CK) Isoenzymes CPK, Creatine Kinase Order code: 1120 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Kinetic Unit code: 101840 S1 0 CPT Code(s): 82550 Ref range: 0-225 U/L Reported: Within 24 hours CPK, Total & MB See: Creatine Kinase, Total & MB Creatine Kinase See: CPK, Creatine Kinase Creatine Kinase (CK) Isoenzymes Order code: 81068 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum Notes: CK-MB and CK-BB are quite labile. Specimens should be frozen. Repeated freeze/thaw cycles destroy CK activity. This test will detect CK macroenzymes. Unacceptable: Plasma and non-frozen specimens. Transport temp: Frozen Method: Enzymatic/Electrophoresis Unit code: 810680 CPT Code(s): 82550, 82552 Ref range: CK-MM: 96-100% CK-MB: 0-4% CK-BB: 0% CK-Macro Type I: 0% CK-Macro Type II: 0% Creatine Kinase, Total Male & Female 0-19 years: By report Male 20 years or older: 20-200 U/L Female 20 years or older: 20-180 U/L Reported: 2-3 days 10-147 Test List BBPL Directory of Services Creatine Kinase, Total & MB Order code: 1589 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Transport temp: Refrigerated. Ship frozen if not sent to lab same day as drawn. Method: Chemiluminescent Immunoassay and Kinetic Unit code: 114201 CPT Code(s): 82553 Ref range: Creatine Kinase, Total: 0-225 U/L Creatine Kinase, MB: 0.0-5.0 ng/mL Relative % Index: 0.0-3.0 % Reported: Within 24 hours Creatinine Clearance Order code: 1455 Preferred specimen: 1.0 mL serum, red top tube or SST and 5.0 mL urine aliquot from a well-mixed 24-hour urine collection. Refrigerate 24-hour urine specimen during collection. No preservative required. Record urine total volume and hours of collection on both the urine container and test request form. Minimum specimen: 0.5 mL serum and 1.0 mL urine aliquot Transport temp: Refrigerated Method: Kinetic and Calculation Unit code: 102459 CPT Code(s): 82575 Ref range: Creatinine, Serum: 0.4-1.5 mg/dL Creatinine, Urine: Excretion: 800-2000 mg/day Clearance: 75-150 mL/min Reported: Within 24 hours Creatinine, Serum Order code: 1015 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Includes: Creatinine Glomerular Filtration Rate S1 0 Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Kinetic Unit code: 101610 CPT Code(s): 82565 Ref range: Creatinine: 0.4-1.5 mg/dL Reported: Within 24 hours Creatinine, Urine Order code: 1020 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Transport temp: Refrigerated Method: Kinetic Unit code: 102450 CPT Code(s): 82570 Ref range: Excretion: 800-2000 mg/day Reported: Within 24 hours CREST Antibody See: Centromere Antibody Test List 10-148 BBPL Directory of Services Crohn Disease Prognostic Panel Order code: 81075 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection. Minimum specimen: 0.25 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 810705 CPT Code(s): 81401, 83520 (x5), 88347 (x2) Ref range: Saccharomyces cerevisiae Antibody (gASCA), IgG: 0-44 Units: Negative 45-50 Units: Equivocal 51 Units or greater: Positive Laminaribioside Carbohydrate Antibody (ALCA), IgG: 0-54 Units: Negative 55-60 Units: Equivocal 61 Units or greater: Positive Mannobioside Carbohydrate Antibody (AMCA), IgG : 0-89 Units: Negative 90-100 Units: Equivocal 101 Units or greater: Positive Chitobioside Carbohydrate Antibody (ACCA), IgA: 0-79 Units: Negative 80-90 Units: Equivocal 91 Units or greater: Positive If only one of the four markers in the Crohn Disease Prognostic Panel is positive, clinical specificity is at least 85 percent. If all four markers are negative and inflammatory bowel disease (IBD) is suspected, testing for ANCA by IFA is recommended to confirm or exclude the possibility of ulcerative colitis (UC). Reported: 1-9 days CRP See: C-Reactive Protein C-Reactive Protein, High Sensitivity S1 0 Cryofibrinogen, Qualitative, Plasma Order code: 5270 Preferred specimen: 3.0 mL plasma, light blue (sodium citrate) top tube. Blood specimen must be drawn in a prewarmed tube and kept at 37ºC until centrifuged. Remove plasma from cells immediately and transfer into a transport tube. Keep plasma at room temperature. Fasting specimen is recommended. Minimum specimen: 2.0 mL plasma Other acceptable: 3.0 mL plasma, lavender (EDTA) or gray (sodium fluoride) top tube. Unacceptable: Refrigerated or frozen specimens, heparinized, lipemic, or grossly hemolyzed specimens. Transport temp: Room temperature Method: Cold precipitation Unit code: 350750 CPT Code(s): 82585 Ref range: Negative Reported: Within 24 hours Cryoglobulin, Qualitative with Reflex to IFE Order code: 5265 Preferred specimen: 4.0 mL serum, red top tube. Blood specimen must be drawn in a prewarmed tube and kept at 37ºC until clotting is complete. Let clot for 1 hour at 37ºC. Remove serum from cells immediately after centrifugation. Transfer serum into a transport tube and maintain at room temperature. Fasting specimen is recommended. Minimum specimen: 2.0 mL serum Notes: If cyoglobulins are present, then serum IFE will be added at an additional charge. Unacceptable: Refrigerated or frozen specimens, separator tubes, lipemic or grossly hemolyzed specimens. Transport temp: Room temperature Method: Cold precipitation Unit code: 350705 CPT Code(s): 82595 Ref range: Negative Reported: 1-3 days 10-149 Test List BBPL Directory of Services Cryoglobulins, Qualitative, Serum Order code: 5260 Preferred specimen: 4.0 mL serum, red top tube. Blood specimen must be drawn in a prewarmed tube and kept at 37ºC until clotting is complete. Let clot for 1 hour at 37ºC. Remove serum from cells immediately after centrifugation. Transfer serum into a transport tube and maintain at room temperature. Fasting specimen is recommended. Minimum specimen: 2.0 mL serum Unacceptable: Refrigerated or frozen specimens, separator tubes, lipemic or grossly hemolyzed specimens. Transport temp: Room temperature Method: Cold precipitation Unit code: 350700 CPT Code(s): 82595 Ref range: Negative Reported: Within 24 hours Cryptococcus Antigen, CSF Order code: 81076 Preferred specimen: 1.0 mL CSF in a sterile plastic screw-cap container. Minimum specimen: 0.25 mL CSF Transport temp: Refrigerated Method: Semi-quantitative Enzyme Immunoassay Unit code: 810760 CPT Code(s): 87327 Ref range: Negative Reported: Within 24 hours Cryptococcus Antigen, Serum Order code: 81900 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.25 mL serum Unacceptable: Specimens collected in anticoagulants are unacceptable. Transport temp: Refrigerated Method: Semi-quantitative Enzyme Immunoassay S1 0 Unit code: 810750 CPT Code(s): 87327 Ref range: Negative Positive specimens are titered. Reported: Within 24 hours Cryptococcus, India Ink Prep See: Fungal Smear Only Cryptosporidium Antigen-EIA Order code: 3469 Preferred specimen: Stool placed in 10% formalin or Cary Blair transport media. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to formalin or Cary Blair medium, adding up to the fill line on the transport vial label. Mix vial well. Stool specimen preserved in formalin or Cary Blair medium is stable for 7 days stored at room temperature. Minimum specimen: 0.5 mL liquid stool or 1 g solid (pea-sized) stool. Other acceptable: Fresh stool specimen in a clean, plastic screw-cap container is acceptable only if the specimen will be received in the testing laboratory within 2 hours of collection. Transport refrigerated. Unacceptable: Stool specimens preserved in PVA medium or multiple specimens (more than one in 24 hours). Transport temp: Room temperature Method: Enzyme Immunoassay Unit code: 401050 CPT Code(s): 87328 Ref range: Negative Reported: 1-3 days Test List 10-150 BBPL Directory of Services Cryptosporidium, Isospora, and Cyclospora Kinyoun Stain Order code: 7400 Preferred specimen: 1 g stool (pea size portion) in 10% formalin vial. Notes: Cryptosporidium Stain is less sensitive than the Cryptosporidium Antigen test. Cryptosporidium, Cyclospora, and Isospora are not detected by the Ova and Parasite exam. Unacceptable: Stool specimen submitted in preservatives other than 10% formalin or unpreserved stool specimen. Transport temp: Room temperature Method: Kinyoun Carbolfuchsin Stain Unit code: 408000 CPT Code(s): 87015, 87207 Ref range: Negative Reported: 1-3 days Cryptosporidium, Isospora, Cyclospora, Microsporidia Stain Order code: 3012 Preferred specimen: 1 g stool (pea size portion) in 10% formalin vial. Notes: Cryptosporidium, Cyclospora, Isospora, and Microsporidia are not detected by the Ova and Parasite exam. Unacceptable: Stool specimen submitted in preservatives other than 10% formalin or unpreserved stool specimen. Transport temp: Room temperature Method: Kinyoun Carbolfuchsin Stain Unit code: 408012 CPT Code(s): 87015, 87207 (x2) Ref range: Negative Reported: 1-3 days Crystals, Body Fluid Order code: 2055 Preferred specimen: 1.0 mL synovial fluid in green (sodium heparin) top tube. Minimum specimen: 2 drops of fluid Notes: Indicate source on test request form and specimen container. Unacceptable: Frozen samples. Do not collect in oxalate, powdered EDTA or lithium heparin anticoagulants. Transport temp: Room temperature. Refrigerate if sample will not arrive in lab within 48 hours after collection. S1 0 Method: Polarized Microscopy Unit code: 201480 CPT Code(s): 89060 Ref range: None Seen Reported: Within 24 hours Crystodigin See: Digitoxin CSF Culture See: Culture, CSF CSF Glucose See: Glucose, CSF CSF IgG Index See: CSF Protein Analysis 10-151 Test List BBPL Directory of Services CSF Protein Analysis Order code: 1700 Preferred specimen: 1.0 mL CSF and 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL CSF and 0.5 mL serum Unacceptable: Extremely lipemic serum specimen Transport temp: Refrigerated Method: Nephelometry Unit code: 112700 CPT Code(s): 82040, 82042, 82784 (x2) Ref range: IgG CSF: Albumin CSF: IgG Serum: Albumin Serum: Albumin Index: IgG Index: Synthesis Rate: 0.00-5.86 mg/dL 13.9-24.6 mg/dL 694-1618 mg/dL 3400-5000 mg/dL <9.00 0.30-0.70 IgG <3.00 mg/day Reported: 1-2 days CSF, Cell Count & Differential See: Cell Count & Differential, CSF CSF, Protein, Total See: Protein, Total, CSF CT/GC DNA See: Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel by SDA CTx See: C-Telopeptide, Beta-Cross-Linked, Serum S1 0 Test List 10-152 BBPL Directory of Services Culture, Acid Fast Bacilli, With Stain Order code: 3020 Preferred specimen: See acceptable specimen types below. Submit specimen in tightly sealed sterile container. Indicate source on test request form. Sputum: 1. A first morning, deep cough specimen is recommended. 2. If a series of 3 specimens is requested, collect specimens on 3 consecutive days at 8-24 hour intervals (24 hours when possible). 3. Collect 5.0-10.0 mL specimen (Min 3.0 mL) in tightly sealed, sterile container. 4. Refrigerate. Urine: 1. A first morning specimen is recommended. Minimum of 10.0 mL. 2. Collect specimen in tightly sealed, sterile container. 3. Refrigerate. Body Fluids & Bronchial Washing: 1. Submit 5.0 mL specimen (Min 1.0 mL) in tightly sealed, sterile container. 2. Refrigerate. Spinal Fluid: 1. Submit 2.0-3.0 mL CSF (Min 1.0 mL) in a sterile screw-cap tube. Collect a separate specimen for chemistry and hematology testing if needed. 2. Submit at room temperature. Tissue: 1. Send tissue specimen in tightly sealed, sterile container. 2. Cover the tissue with sterile saline to prevent drying. 3. Keep at room temperature. Wound Aspirates or Drainage: 1. Remove surface exudates by wiping with sterile saline or 70% alcohol. Collect fluid abscess material with a Luer tip syringe and/or remove material from the leading edge of the wound aseptically. For open lesions/abscesses, aspirate, if possible, material from under the margin of the lesion/abscess. 2. Note: Specimens submitted on swabs are not recommended. Please submit aspirate material, drainage fluid, or tissue for optimal quality of results. 3. Note: When submitting a syringe, remove the needle prior to submission and cap with a sterile syringe tip cap. 4. Refrigerate. Feces: 1. Submit a minimum of 1 g solid stool or 1.0-5.0 mL liquid stool in a clean leak-proof container. 2. Refrigerate. Bone Marrow & Blood: 1. Submit 5.0 mL blood (Min 1.0 mL) or 2.0 mL bone marrow (Min 0.5 mL) in either yellow (SPS) top tube or lysis-centrifugation tube. 2. Keep at room temperature. Notes: Please indicate on test request form when the presence of M. genavense or M. haemophilum is suspected, as special procedures are required for isolation of these species. Culture is incubated for 8 weeks before determined to be negative. CPT code 87015 for Concentration will be added at an additional charge for body fluid, respiratory, stool, tissue, and urine specimens. S1 0 Unacceptable: Specimens not stored at the proper temperature, blood or bone marrow not submitted in SPS or lysis-centrifugation tubes, or specimens greater than 72 hours old. Transport temp: Refrigerated: Sputum, Urine, Body Fluids, Bronchial Washing, Wound Aspirates or Drainage, Feces. Room temperature: Spinal Fluid (CSF), Tissue, Bone Marrow, Blood. Method: Fluorescent stain. Mycobacterial culture technique. Unit code: 400000 CPT Code(s): 87116, 87206 Reported: Stain: Within 24 hours; Culture: Within 8 weeks Culture, Beta Strep, Genital See: Culture, Group B Screen Culture, Beta Strep, Throat Order code: 3070 Preferred specimen: Collect throat specimen using a sterile culture swab. Swab only the back of the throat between and around the tonsillar area. Avoid cheeks, teeth, etc. Do not allow the swab to touch the tongue. Do not refrigerate. Notes: If Group A Strep Rapid Antigen is requested, order 3069. Unacceptable: Swab with wooden shaft or dried swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 400300 CPT Code(s): 87081 Reported: Within 48 hours 10-153 Test List BBPL Directory of Services Culture, Blood Order code: 3080 Preferred specimen: 1. Blood cultures are to be drawn into BacT/Alert culture bottles, available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. All bottles should be kept at room temperature before and after collection. Always use sterile techniques with specimen collection. Sterilize the top of the blood culture bottles with alcohol and allow to air dry before injecting the blood into the bottle. 2. Adult Collection: Two bottles should be collected per draw - one aerobic with blue cap and one anaerobic with purple cap. Aerobic Media: 40 mL Tryptic Soy Agar supplemented with CO2 and SPS. Aseptically add 5-10 mL of blood to bottle - notice gradations on side of bottle. Anaerobic Media: 40 mL Tryptic Soy Agar supplemented with SPS, reducing agents and oxygen-free nitrogen. Aseptically add 510 mL of blood to bottle - notice gradations on side of bottle. DO NOT OVERFILL. 3. Pediatric Collection: Pediatric bottles have a yellow cap. Each bottle contains 20 mL of BHI broth supplemented with pyridoxine. Add 1-4 mL of blood to each bottle. Only one bottle is needed for each pediatric draw. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Clotted specimens or specimens not collected in proper culture media. Transport temp: Ambient Method: Bacteriologic Culture Techniques/BacT/Alert 3-D Unit code: 400500 CPT Code(s): 87040 Reported: Within 5 days Culture, Body Fluid Order code: 3095 Preferred specimen: Aspirated body fluid: Transport in a sterile leak-proof container, yellow top SPS vacutainer tube, or sterile capped syringe without needle. Submit to laboratory ASAP at room temperature. Peritoneal dialysate fluid: If specimen will arrive in laboratory within 12 hours of collection, transport refrigerated in a sterile leakpoof container. If specimen transport time will be greater than 12 hours from time of collection, submit specimen in Blood Culture bottles. Sterilize top of bottle with alcohol and allow to air dry. Aseptically inject 10 mL fluid into a SA (blue-cap aerobic bottle) and 10 mL fluid into a SN (dark purple-cap anaerobic bottle) and transport at room temperature within 24 hours. Notes: A Gram Stain Smear (order code 3420) must be ordered separately, if desired. Identification and susceptibility tests will be performed if indicated, at an additional charge. Other acceptable: Body fluid submitted in blood culture bottles. Sterilize top of blood culture bottles with alcohol, allow to air dry. For large volume specimens, aseptically inject 10 mL of fluid into a SA (blue-cap aerobic bottle) and 10 mL fluid into a SN (dark purple-cap anaerobic bottle). For small volume specimens, place 1-4 mL into a PF (yellow-cap pediatric bottle). Transport specimen at room temperature within 24 hours. Unacceptable: Specimen in non-sterile container, syringe with needle, or green, purple, or blue top vacutainer tube. Specimen submitted on dried culture swab or wooden shaft swab. Frozen specimen. Transport temp: Room temperature: Body fluid and any fluid in blood culture bottles Refrigerated: Peritoneal fluid <12 hours old S1 0 Method: Bacteriologic Culture, Aerobic and Anaerobic. Unit code: 400600 CPT Code(s): 87070, 87075 Ref range: No growth Reported: Within 48 hours Fluid sumitted in blood culture bottles - within 5 days. Broth will be held for 7 days. If the broth grows, an amended report will be issued; otherwise, no further report will be sent. Culture, Bronchial Alveolar Lavage (BAL) See: Culture, Lower Respiratory Tract Culture, Bronchial Alveolar Lavage (BAL), and Gram Stain See: Culture, Lower Respiratory Tract, and Gram Stain Culture, Bronchial Washings See: Culture, Lower Respiratory Tract Culture, Candida See: Fungal Culture Test List 10-154 BBPL Directory of Services Culture, CSF Order code: 3100 Preferred specimen: Collect CSF in sterile screw-cap or snap-cap tubes. Collect 4.0-5.0 mL for adults and 0.5-1.0 mL for children. Transport to the laboratory in the collection tube as soon as possible. Do not refrigerate. If only one tube is collected, send to the Microbiology laboratory first. If more than one tube is obtained, the second or third collection tube should be sent to the Microbiology laboratory for culture. Minimum specimen: 1.0 mL CSF for adults Notes: CSF culture does not include a gram stain. If gram stain is needed order 3420 Gram Stain Smear. Identification and susceptibility tests will be performed if indicated, at an additional charge. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 401100 CPT Code(s): 87070 Reported: Negative cultures within 72 hours. Note: Broth will be held for 7 days. If the broth grows, an amended report will be issued; otherwise, no further report will be sent. Culture, Cytomegalovirus Order code: 81685 Preferred specimen: Collect 5.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.0 mL whole blood, 0.5 mL fluid. Notes: Cytomegalovirus by PCR is a more sensitive method for the detection of CMV viremia and central nervous system infections, especially in the immunocompromised patient. Other acceptable: Bronchoalveolar lavage (BAL) or urine. Transfer 2.0 mL fluid to a sterile container or viral transport media. Or throat swab or tissue placed in viral transport media. Indicate source on test request form. Unacceptable: Stool, rectal swab, and CSF specimens. Whole blood in viral transport media. Calcium alginate, eSwab, dry, or wood swabs. Frozen specimens. Transport temp: Refrigerated. Do not freeze. Method: Cell Culture/Immunofluorescence Unit code: 808500 CPT Code(s): 87254 Ref range: Culture negative for CMV by early antigen test. Reported: 1-5 days S1 0 Culture, Dialysate Fluid See: Culture, Body Fluid Culture, Ear Order code: 3120 Preferred specimen: Collect ear drainage using a sterile culture transport swab. Do not refrigerate. Transport swab can maintain organism viability up to 72 hours. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Dried culture swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 401200 CPT Code(s): 87070 Reported: Within 48 hours Culture, Environmental Order code: 3400 Preferred specimen: Use a sterile culture swab to collect specimen. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 401300 CPT Code(s): 87070 Reported: Within 48 hours 10-155 Test List BBPL Directory of Services Culture, Eye Order code: 3140 Preferred specimen: Collect eye culture using sterile culture transport swab. Corneal scrapings should be collected using a sterile corneal spatula and placed directly on appropriate culture media or placed on a sterile culture transport swab. Do not refrigerate. Transport swab can maintain organism viability up 72 hours. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Dried culture swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 401400 CPT Code(s): 87070 Reported: Within 48 hours Culture, Fungal See: Fungal Culture Culture, Fungal and Stain See: Fungal Culture and Stain Culture, Fungal and Stain, Blood See: Fungal Culture and Stain, Blood Culture, Fungal and Stain, Skin, Hair or Nails See: Fungal Culture and Stain, Skin, Hair or Nails Culture, Fungal, Blood See: Fungal Culture, Blood S1 0 Culture, Fungal, Skin, Hair or Nails See: Fungal Culture, Skin, Hair or Nails Culture, Gardnerella Order code: 3720 Preferred specimen: Use a sterile Culture swab to collect genital specimen. Send specimen to the laboratory as soon as possible. Unacceptable: Dried culture swab Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 401800 CPT Code(s): 87081 Ref range: No Gardnerella Isolated Reported: Within 72 hours Culture, Genital Order code: 3180 Preferred specimen: Vaginal, cervical, urethral or penile secretions: Collect specimen using a sterile culture transport swab. Transport swab can maintain organism viability up to 72 hours. Semen or IUD: Submit in sterile sealed container. Transport ASAP within 24 hours of collection. Do not refrigerate specimens. Record source on test request form. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. IUD specimens will be cultured for aerobes and for anaerobes at an additional charge. Unacceptable: Dried culture swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 402000 CPT Code(s): 87070 Reported: IUD specimens reported after 5 days. All other specimens reported within 72 hours. Test List 10-156 BBPL Directory of Services Culture, Group B Streptococcus Order code: 3060 Preferred specimen: Collect both a vaginal and rectal specimen. Using a swab from a culturette container with either Amies or Stuart's media without charcoal, swab the lower vagina (vaginal introitus), followed by the rectum (ie, insert swab through the anal sphincter) using the same swab. Move swab from side to side, or rotate the swab at the collection site, allowing several seconds for absorption of organisms by the swab. Alternately, two swabs may be used, one for vaginal and one for rectal - use a double swab culturette. Place the swab/swabs back into the culturette and transport to the laboratory at room temperature as soon as possible. NOTE that cervical specimens are not recommended and a speculum should not be used for collection. Record source of specimen on test request form. Notes: Patient should be checked for Group B Strep during their third trimester of pregnancy. Other acceptable: Sterile culture swabs may be submitted in Todd Hewitt Broth available through BBPL Client Services. Broth may be incubated 3537°C for 18-24 hours prior to transport - no longer. If broth has been incubated prior to transport, please record length of incubation on broth tube. Unacceptable: Dried culture swabs. Swabs with wooden shafts. Specimen greater than 72 hours old. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 400400 CPT Code(s): 87081 Reported: Within 3 days Culture, Group B Streptococcus with Sensitivities Order code: 3061 Preferred specimen: Collect both a vaginal and rectal specimen. Using a swab from a culturette container with either Amies or Stuart's media without charcoal, swab the lower vagina (vaginal introitus), followed by the rectum (ie, insert swab through the anal sphincter) using the same swab. Move swab from side to side, or rotate the swab at the collection site, allowing several seconds for absorption of organisms by the swab. Alternately, two swabs may be used, one for vaginal and one for rectal - use a double swab culturette. Place the swab/swabs back into the culturette and transport to the laboratory at room temperature as soon as possible. NOTE that cervical specimens are not recommended and a speculum should not be used for collection. Record source of specimen on test request form. Notes: Sensitivities will be performed on Group B Streptococcus isolate at an additional charge. Some patients may be allergic to penicillins and susceptibility testing of the organism is indicated. Patient should be checked for Group B Strep during their third trimester of pregnancy. Other acceptable: Sterile culture swabs may be submitted in Todd Hewitt Broth available through BBPL Client Services. Broth may be incubated 3537°C for 18-24 hours prior to transport - no longer. If broth has been incubated prior to transport, please record length of incubation on broth tube. Unacceptable: Dried culture swabs. Swabs with wooden shafts. Specimen greater than 72 hours old. Transport temp: Room temperature Method: Bacteriologic culture techniques S1 0 Unit code: 400410 CPT Code(s): 87081 Reported: Within 3 days Culture, Joint Fluid See: Culture, Body Fluid Culture, Knee Fluid See: Culture, Body Fluid Culture, Legionella Species Order code: 83842 Preferred specimen: Respiratory tract secretions, aspirates, BAL, tissues, fluids, sputum, or abscess material, or pericardial fluid. Transport fluids in a sterile container frozen. Place tissue on gauze moistened with sterile non-bacteriostatic saline to prevent drying and transport in a sterile container frozen. Source of specimen is preferred. Minimum specimen: 0.5 mL fluids Other acceptable: Whole blood in SPS tube, refrigerated. Send immediately to laboratory. Unacceptable: Urine, stool, wounds, or other culture material from non-respiratory sites. Dry specimens. Specimens in preservatives or viral transport medium. Transport temp: Frozen Method: Culture/Identification Unit code: 823800 CPT Code(s): 87081 Ref range: Culture negative for Legionella species. Reported: Positives are reported as soon as detected. Final: Negative at 7 days 10-157 Test List BBPL Directory of Services Culture, Lower Respiratory Tract Order code: 3240 Preferred specimen: Collect lower respiratory specimen: Sputum, tracheal aspirate, bronchial wash, bronchial alveolar lavage (BAL), or transtracheal aspirate. For sputum, carefully instruct the patient to cough deeply (not to spit) into a sterile screw-top container. The first morning specimen is best (no 24 hour collection). Transport at least 5 mL of sputum or fluid in a tightly sealed container. Notes: It is strongly recommended that a gram stain be performed on all expectorated sputum specimens to determine their acceptability for culture. Please order Culture, Lower Respiratory Tract, and Gram Stain (order code 3241) unless a gram stain has already been performed by the client at the time of collection. Identification and susceptibility tests will be performed if indicated, at an additional charge. Agents such as Bordetella pertussis, Chlamydia pneumoniae , Corynebacterium diphtheriae, Legionella pneumophila, Mycoplasma pneumoniae, and Acid-Fast Bacilli (Mycobacterium tuberculosis), and Fungus require special laboratory measures for isolation and therefore require separate orders for each specific agent. Unacceptable: Swabs. Specimens received after 72 hours of collection. Multiple specimens (more than one in 24 hours) or frozen specimens. Transport temp: Refrigerated Method: Bacteriologic culture techniques Unit code: 402600 CPT Code(s): 87070 Reported: Within 48 hours Culture, Lower Respiratory Tract, and Gram Stain Order code: 3241 Preferred specimen: Collect lower respiratory specimen: Sputum, tracheal aspirate, bronchial wash, bronchial alveolar lavage (BAL), or transtracheal aspirate. For sputum, carefully instruct the patient to cough deeply (not to spit) into a sterile screw-top container. The first morning specimen is best (no 24 hour collection). Transport at least 5 mL of sputum or fluid in a tightly sealed container. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Agents such as Bordetella pertussis, Chlamydia pneumoniae , Corynebacterium diphtheriae, Legionella pneumophila, Mycoplasma pneumoniae, and Acid-Fast Bacilli (Mycobacterium tuberculosis), and Fungus require special laboratory measures for isolation and therefore require separate orders for each specific agent. Unacceptable: Specimens submitted on swabs. Specimens received after 72 hours of collection. Multiple specimens (more than one in 24 hours) or frozen specimens. Transport temp: Refrigerated Method: Bacteriologic culture techniques/Gram Stain Unit code: 402601 CPT Code(s): 87070, 87205 S1 0 Reported: Within 48 hours Culture, Nasopharyngeal Order code: 3220 Preferred specimen: Routine Nasal: Use a sterile culture transport swab to swab the anterior nares only. Nasopharynx: Using a naso-pharyngeal swab, collect the specimen by passing through the nose into the nasopharynx. Allow swab to remain for a few seconds and carefully withdraw. Place naso-pharyngeal swab into transport tube. Do not refrigerate. Swabs can maintain organism viability up 72 hours. Notes: If only interested in MRSA, order 3204 MRSA Culture. Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Dried culture swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 402200 CPT Code(s): 87070 Reported: Within 48 hours Culture, Neisseria gonorrhoeae (GC) Only Order code: 3160 Preferred specimen: Urethral, vaginal, cervical, rectal, throat, or prostatic fluid. Collect specimen on sterile culture transport swab. Do not refrigerate. Transport swab can maintain organism viability up 72 hours. Notes: Indicate specimen source on test request form. Other acceptable: Culture swab in ACT-I tube. Keep ACT-I tubes at room temperature before and after inoculation. Unacceptable: Dried culture swab, calcium alginate or wooden shaft swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 401900 CPT Code(s): 87081 Reported: Within 72 hours Culture, Peritoneal Fluid See: Culture, Body Fluid Test List 10-158 BBPL Directory of Services Culture, Pleural Fluid See: Culture, Body Fluid Culture, Sputum See: Culture, Lower Respiratory Tract Culture, Sputum, and Gram Stain See: Culture, Lower Respiratory Tract, and Gram Stain Culture, Stool with Shiga Toxin 1 and 2 by EIA Order code: 3260 Preferred specimen: Stool placed in Cary Blair transport media. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to Cary Blair medium, adding up to the fill line on the Cary Blair vial label. Mix vial well. Stool specimen preserved in Cary Blair medium is stable for 72 hours refrigerated. If multiple specimens are indicated, collect on three separate days. Record the collection date and time on each specimen vial. Cary Blair media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Minimum specimen: 1.0 mL liquid stool or 1 g solid (pea-sized) formed stool. Notes: Culture detects Salmonella, Shigella, Campylobacter, and E. Coli O157:H7 organisms. Routine stool culture includes Shiga Toxin 1 and 2 testing. Cultures for other pathogens must be ordered separately. Do not order stool culture for detection of Clostridium difficile toxin, instead order 53810 Clostridium difficile Toxin by PCR. Other acceptable: Fresh stool specimen in a clean, plastic screw-cap container is acceptable only if the specimen will be received in the testing laboratory within 24 hours of collection. Transport refrigerated. For acceptable specimens for infants, contact the BBPL Microbiology department. Unacceptable: Multiple specimens (more than one in 24 hours), specimens in inappropriate transport media (O&P preservatives), unpreserved stool specimens received at room temperature, frozen specimens, dried culture swabs or wooden shaft swabs. Transport temp: Refrigerated Method: Bacteriologic Culture Techniques and Enzyme Immunoassay Unit code: 402710 CPT Code(s): 87045, 87046, 87427 (x2) Reported: Within 3 days S1 0 Culture, Synovial Fluid See: Culture, Body Fluid Culture, Throat, Routine Order code: 3280 Preferred specimen: Collect throat specimen using a sterile culture transport swab. Swab only the back of the throat between and around the tonsillar area. Avoid cheeks, teeth, etc. Do not allow swab to touch the tongue. Do not refrigerate. Transport swab can maintain organism viability up 72 hours. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Dried culture swab or wooden shaft swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 402800 CPT Code(s): 87070 Reported: Within 48 hours Culture, Tissue Order code: 3340 Preferred specimen: Send tissue sample in tightly sealed sterile container. Cover the tissue with sterile saline to prevent drying. Send to laboratory ASAP at room temperature. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Tissue specimens in formalin. Transport temp: Room temperature Method: Bacteriologic Culture, Aerobic and Anaerobic Unit code: 403300 CPT Code(s): 87070, 87075, 87176 Ref range: No growth Reported: Within 48 hours. Note: Broth will be held for 7 days. If the broth grows, an amended report will be issued; otherwise, no further report will be sent. Culture, Tracheal Aspirate See: Culture, Lower Respiratory Tract 10-159 Test List BBPL Directory of Services Culture, Tracheal Aspirate, and Gram Stain See: Culture, Lower Respiratory Tract, and Gram Stain Culture, Transtracheal Aspirate See: Culture, Lower Respiratory Tract Culture, Transtracheal Aspirate, and Gram Stain See: Culture, Lower Respiratory Tract, and Gram Stain Culture, Urine, Routine Order code: 3300 Preferred specimen: Collect 5 mL of urine (clean-catch, catheter, cystoscopic, or suprapubic) into a sterile screw-top container. For a clean-catch urine specimen, the patient must thoroughly clean the urethral and/or vaginal area with soap rather than disinfectant before collection. If obtaining a catheterized urine specimen, collect from the catheter line into a sterile container. Do not culture from the indwelling catheter bag. Do not culture Foley tips. Note on test request form if urine is a catheterized specimen. Transport urine to the laboratory as soon as possible after collection. If transport will be delayed more than 2 hours, refrigerate urine specimen (stable for 24 hours refrigerated). Refrigeration is not necessary if 3-4 mL of the urine is transferred to a urine transport set (yellow top vacuette with preservative, stable for 72 hours at room temperature). Minimum specimen: 0.2 mL urine Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Urine from a catheter bag or Foley catheter tip. Delay in transport to laboratory: greater than 24 hours for unpreserved refrigerated urine or greater than 72 hours for room temperature preserved urine. Specimens in non-sterile container or expired transport container. Frozen specimens. Transport temp: Unpreserved urine refrigerated Preserved urine at room temperature Method: Bacteriologic culture techniques Unit code: 402900 CPT Code(s): 87086 Ref range: No growth Reported: Within 2 days S1 0 Culture, Viral See: Viral Culture, Non-Respiratory Viral Culture, Respiratory Culture, Wound Order code: 3320 Preferred specimen: When collecting surface wound cultures, decontaminate the surrounding skin, open the lesion and express exudate onto a sterile culture transport swab. Transport to the laboratory immediately or place into transport media. When collecting deep wound cultures which could include anaerobic organisms, an ACT-I culture transport tube can be used in addition to the routine culture swab. If an abscess is present, a syringe and needle should be used to aspirate the fluid. Send the syringe and fluid to the laboratory for plating. Do not submit syringe with the needle attached. Transport swab can maintain organism viability up to 72 hours. Please record specific site on test request form. Notes: Identification and susceptibility tests will be performed if indicated, at an additional charge. Unacceptable: Dried culture swab or wooden shaft swab. Transport temp: Room temperature Method: Bacteriologic culture techniques, Aerobic and Anaerobic Unit code: 403000 CPT Code(s): 87070, 87075 Ref range: No growth Reported: Within 48 hours. Note: Broth will be held for 7 days. If the broth grows, an amended report will be issued; otherwise, no further report will be sent. Culture, Yeast Screen Order code: 3740 Preferred specimen: Collect specimen using a sterile culture transport swab. Transport to laboratory as soon as possible. Transport swab can maintain organism viability up 72 hours. Notes: The Screen reports only presence or absence of yeast. If identification of yeast is desired, order appropriate Fungal Culture code. Unacceptable: Dried culture swab. Transport temp: Room temperature Method: Bacteriologic culture techniques Unit code: 403100 CPT Code(s): 87081 Reported: Within 48 hours Test List 10-160 BBPL Directory of Services Culture, Yersinia Order code: 3760 Preferred specimen: Stool placed in Cary Blair transport media. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to Cary Blair medium, adding up to the fill line on the Cary Blair vial label. Mix vial well. Stool specimen preserved in Cary Blair medium is stable for 72 hours refrigerated. Minimum specimen: 1.0 mL liquid stool or 1 g solid (pea-sized) formed stool. Notes: If multiple stool specimens are indicated, collect on three separate days. Record the collection date and time on each specimen vial. Other acceptable: Fresh stool specimen in a clean, plastic screw-cap container is acceptable only if the specimen will be received in the testing laboratory within 24 hours of collection. Transport refrigerated. Unacceptable: Multiple specimens (more than one in 24 hours), specimens in inappropriate transport media (O&P preservatives), unpreserved stool specmens received at room temperature, frozen specimens, dried culture swabs or wooden shaft swabs. Transport temp: Refrigerated Method: Bacteriologic culture techniques Unit code: 403200 CPT Code(s): 87046 Ref range: No Yersinia species isolated. Reported: Within 48 hours Cyanide, Blood Order code: 81930 Preferred specimen: 4.0 mL whole blood, green (sodium or lithium heparin) top tube, in original collection tube. Minimum specimen: 3.0 mL whole blood Notes: Do not refrigerate or freeze specimen. Other acceptable: 4.0 mL whole blood, lavender (EDTA) top tube, in original collection tube. May also transfer whole blood to a plastic transport tube. Unacceptable: Serum or plasma, clotted or hemolyzed specimens, frozen or refrigerated specimens. Transport temp: Room temperature Method: Quantitative Colorimetric Unit code: 810950 CPT Code(s): 82600 Ref range: Non-smokers: Less than 20 µg/dL Smokers: Less than 40 µg/dL Toxic Level: Greater than 100 µg/dL S1 0 Cyanide poisoning can cause hypoxia, dizziness, weakness and mental and motor impairment. Elevated cyanide concentrations rarely indicate toxicity for patients on nitroprusside therapy. Thiocyanate should be monitored in patients on nitroprusside therapy for potential toxicity No laboratory test is available to assess cyanide toxicity in a patient who is on nitroprusside therapy; this test should not be ordered when the patient is on nitroprusside. However, thiocyanate toxicity may occur with long-term nitroprusside use (longer than seven to 14 days with normal renal function and three to six days with renal impairment at greater than 2 µg/kg/min infusion rates). Thiocyanate levels may be monitored on an every other day basis to assess potential thiocyanate toxicity and to indicate possible adjustments in dosage. Reported: 1-5 days Cyclic AMP, Urine Order code: 81144 Preferred specimen: 5.0 mL urine aliquot from a unpreserved, well-mixed random urine collection. Minimum specimen: 1.0 mL urine aliquot from a well-mixed random or 24-hour collection. Other acceptable: 5.0 mL urine aliquot from a well-mixed 24-hour urine collection that is preserved with 1 g boric acid per 100 mL urine. Refrigerate 24-hour specimen during collection. Record total volume and hours of collection on both the urine container and test request form. Transport temp: Frozen Method: Radioimmunoassay Unit code: 811044 CPT Code(s): 82030 Ref range: 0.5-10.0 nmol/mL Reported: 1-8 days Cyclic Citrullinated Peptide Antibody, IgG Order code: 5032 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (lithium heparin) top tube. Unacceptable: Severely hemolyzed, lipemic, or heat-inactivated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 350320 CPT Code(s): 86200 Ref range: Negative: 0-5.0 U/mL Positive: >5.0 U/mL Reported: 1-5 days 10-161 Test List BBPL Directory of Services Cyclin D See: IGH/BCL-1 FISH Study Cyclospora Stain See: Cryptosporidium, Isospora, and Cyclospora Stain Cyclosporine A Order code: 81126 Preferred specimen: 1.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 0.25 mL EDTA whole blood. Notes: Pre-dose (trough) levels should be drawn. Unacceptable: Serum, plasma, clotted specimens, and specimens left at room temperature for longer than 24 hours. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 811256 CPT Code(s): 80158 Ref range: Therapeutic Range: 100-400 ng/mL Kidney transplant (in combination with Everolimus): 1 month post-transplant: 100-200 ng/mL 2-3 months post-transplant: 75-150 ng/mL 4-5 months post-transplant: 50-100 ng/mL 6-12 months post-transplant: 25-50 ng/mL Heart transplant: Up to 3 months post-transplant: 350-525 ng/mL 4 months and older post-transplant: 145-350 ng/mL Liver transplant: 290-525 ng/mL Toxic value: Greater than 700 ng/mL The general therapeutic range for cyclosporine A is 100-400 ng/mL. The optimal therapeutic range for a given patient may differ from this suggested range based on the indication for therapy, treatment phase (initiation or maintenance), use in combination with other drugs, time of specimen collection relative to prior dose, type of transplanted organ, and/or the therapeutic approach of the transplant center Reported: 1-2 days Cystatin C S1 0 Order code: 81129 Preferred specimen: 1.0 mL serum, SST. Allow specimen to clot completely at room temperature. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.4 mL serum Unacceptable: Grossly hemolyzed specimens. Transport temp: Refrigerated Method: Quantitative Nephelometry Unit code: 811290 CPT Code(s): 82610 Ref range: 0-3 months: 0.8-2.3 mg/L 4-11 months: 0.7-1.5 mg/L 1-17 years: 0.5-1.3 mg/L 18 years and older: 0.5-1.0 mg/L Reported: 1-2 days Cystic Fibrosis Mutation Screening Order code: 36995 Preferred specimen: 5.0 mL whole blood, lavender (EDTA), light blue (sodium citrate), or yellow (ACD Solution A or B) top tube. Transport whole blood refrigerated. Frozen is also acceptable. Minimum specimen: 3.0 mL whole blood Notes: Separate samples should be submitted when multiple test are ordered. Other acceptable: Liquid Based PAP Media Unacceptable: Samples collected in heparin anticoagulant. Transport temp: Refrigerated Method: Multiplex PCR with Multiplex Electrochemical Detection Unit code: 536995 CPT Code(s): 81220 Ref range: None detected. Reported: 1-7 days Test List 10-162 BBPL Directory of Services Cystine, Urine-Quantitative Order code: 82000 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or other timed urine collection. Refrigerate 24-hour specimen during collection period. Immediately after completion of collection, mix urine well, aliquot urine into a plastic transport tube and freeze. Record total volume and hours of collection on both the urine container and test request form. Avoid dilute urine when possible. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 3.0 mL urine Notes: Clinical information (age, gender, diet, drug therapy, and family history) is needed for appropriate interpretation. A Patient History for Biochemical Genetic Testing form along with test request form must be submitted with specimen. Other acceptable: Other timed urine collections. Unacceptable: Room temperature or refrigerated specimens. Transport temp: CRITICAL FROZEN Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 811400 CPT Code(s): 82131 Ref range: 0-2 months: 14-573 umol/g CRT 3-8 months: 28-461 umol/g CRT 9 months-2 years: 34-186 umol/g CRT 3-12 years: 26-98 umol/g CRT 13 years and older: 12-81 umol/g CRT Reported: 3-7 days Cytochrome P450 2C19 (CPY2C19) 9 Mutations Order code: 81444 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Notes: Counseling and informed consent are recommended for genetic testing. Molecular Genetic Testing consent forms are available through BBPL Client Services. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Detection Primer Extension Unit code: 811440 CPT Code(s): 81225 Ref range: By report Reported: 7-14 days S1 0 Cytogenomic SNP Microarray Order code: 87952 Preferred specimen: 5.0 mL whole blood, green (sodium heparin) or lavender (EDTA). Peripheral blood required. Minimum specimen: 1.0 mL whole blood Notes: A Genomic Microarray Patient Clinical Information form must be submitted with the test request form and specimen. Unacceptable: Frozen or clotted specimens. Transport temp: Room temperature Method: Genomic Microarray (Oligo-SNP Array) Unit code: 807952 CPT Code(s): 81229 Ref range: By report Reported: 10-14 days (Results requiring the completion of FISH testing may exceed the standard TAT) Cytology, Anal Pap Test Order code: 4880 Preferred specimen: Anal sample collected in SurePath collection vial. Collection: Moisten a Dacron swab with water (not lubricant) and insert approximately 1.5 to 2 inches into the anal canal. Rotate the swab in a spiral motion and apply some pressure to the wall of the anus as the swab is removed. Place the Dacron swab head in a SurePath collection vial. Cap the vial tightly. Notes: Use of lubricants to collect sample may render the specimen as unsatisfactory. The frosted end of the microscopic slide(s) or collection vial must be labeled with two (2) person specific identifiers. Submit specimen with a completed Cytology test request form. Other acceptable: Anal swab sample spread on a glass microscopic slide(s). Immediately fix slide(s) with cytologic spray fixative or place in slide holder pre-filled with 95% alcohol. Unacceptable: Specimens improperly labeled. Specimens submitted in expired collection reagent. Specimens collected by cotton swab or swab with wooden shaft. Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Unit code: 604880 CPT Code(s): 88160 Ref range: By report Reported: 2-3 days 10-163 Test List BBPL Directory of Services Cytology, Breast Secretion Order code: 4125 Preferred specimen: Direct collection of nipple secretion on a glass microscopic slide (single-end frosted). Collection: Gently grip subareolar area and nipple with thumb and forefinger to produce pea size drop of secretion. Touch clean slide to the nipple. Immediately fix slide with cytologic spray fixative or place in slide holder pre-filled with 95% alcohol. Notes: The frosted end of slide must be labeled with two (2) person specific identifiers and specimen site (include left or right). Submit specimen with a completed Cytology test request form. Unacceptable: Slide with improper identification. Slide with improper fixative. Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Unit code: 604125 CPT Code(s): 88104 Ref range: By report Reported: 2-3 days Cytology, Bronchial Washings and Brushings Order code: 4175 Preferred specimen: Washings: Submit with an equal volume of cytology fixative. Print patients name and specimen site on the container and complete a Cytology requisition. Brushings: Prepare slides by rolling material on a slide. Fix immediately with spray fixative. The brush(es) used to prepare slides may also be swished in a container of fixative to dislodge additional material and send to the laboratory. Notes: Label the slides and the containers with two (2) person specific identifiers and specimen source. Submit specimen with a completed Cytology test request form that includes clinicial history and appropriate ICD9 code(s). Other acceptable: Fluid without cytology fixative. Must refrigerate and ship refrigerated. Unacceptable: Improper identification, fixation, or 24 hr specimen. Transport temp: Room temperature fixed. Refrigerated unfixed. Method: Routine Cytopathologic Evaluation Unit code: 604175 CPT Code(s): 88112 Reported: 1-2 days Cytology, Conventional Pap Smear (1 slide) Order code: 4015 Preferred specimen: One fixed smear using standard PAP collection methods. Spray slide immediately with cytology fixative. Do not allow to air dry before fixation. Notes: The frosted end of the slide and slide holder must be labeled with two (2) person specific identifiers. Submit specimen with a completed Cytology test request form that includes clinical history and appropriate ICD9 code(s). Unacceptable: Specimens improperly labeled. Slides broken in transit. Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Unit code: 604015 Ref range: See laboratory report. Cytology, CSF See: Cytology, Non-Gyn Miscellaneous Test List 10-164 S1 0 BBPL Directory of Services Cytology, Fine Needle Aspiration (FNA) Order code: 4400 Preferred specimen: Collection: FNA collection kits are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Refer to Fine Needle Aspiration (FNA) Specimen Collection for detailed instructions. Specimen: Aspirated cellular material from lesions/masses of all body sites submitted for evaluation and detection of malignant diseases. Fine needle aspirations should include the following three components for optimal cytologic results.Two fixed slides: Place one small drop of specimen on a glass side. Take a second glass slide and smear the drop of material. Immediately place both slides in plastic container with cytology fixative. Two air dried slides: Place one small drop of specimen on a glass slide. Take a second glass slide and smear the drop of material. Allow both slides to dry. Place air dried slides in plastic cytology transport container. Remaining Fluid: The remaining fluid is submitted in a cytology container with equal amount of CytoRich fixative. After the direct smears have been prepared, the needle is removed from the syringe. The syringe is used to draw up the cytology fixative fluid and then expel the remaining specimen into the cytology container. The lid must be placed on tightly for shipping to the laboratory. Notes: The frosted end of the microscopic slides and collection containers must be labeled with two (2) person specific identifiers and detailed specimen information (e.g., left breast or right breast). Submit specimen with a completed Cytology request form that includes clinical history and appropriate ICD9 code(s). Unacceptable: Syringes with or without needles. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Unit code: 604400 CPT Code(s): 88173 Reported: 1-2 days Cytology, Fluid Order code: 4080 Preferred specimen: Submit fluid with an equal volume of cytology fixative. Notes: The specimen must be labeled with two (2) person specific identifiers and specimen source. Submit specimen with a completed Cytology test request form that includes clinicial history and appropriate ICD9 code(s). Other acceptable: Fluid without cytology fixative. Must refrigerate and ship refrigerated. Unacceptable: Improper identification, fixation, or 24 hr specimen. Transport temp: Ambient fixed, Refrigerated unfixed Method: Routine Cytopathologic Evaluation Unit code: 604080 S1 0 CPT Code(s): 88112 Reported: 1-2 days Cytology, Non-Gyn Miscellaneous Order code: 4100 Preferred specimen: Submit fluid (3-5 mL) with an equal volume of cytology fixative. Cytology fixative is available through BBPL Client Services or online using BBPL Electronic Supply Order Form. Record the source on the test request form. Minimum specimen: 1 mL fluid Notes: The specimen must be labeled with two (2) person specific identifiers and specimen source. Submit specimen with a completed Cytology test request form that includes clinicial history and appropriate ICD9 code(s). Other acceptable: Fluid without cytology fixative if refrigerated. Unacceptable: Syringes with or without needles. Specimens improperly labeled. Transport temp: Room temperature fixed Refrigerated unfixed Method: Routine Cytopathologic Evaluation Unit code: 604100 CPT Code(s): 88112 Reported: 1-2 days Cytology, Sputum Order code: 4050 Preferred specimen: Submit sputum (early morning deep cough specimen preferred) with an equal volume of cytology fixative. Notes: The specimen must be labeled with two (2) person specific identifiers and specimen source. Submit specimen with a completed Cytology test request form that includes clinicial history and appropriate ICD9 code(s). Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Unit code: 604050 CPT Code(s): 88112 Reported: 1-2 days 10-165 Test List BBPL Directory of Services Cytology, SurePath Liquid-Based Pap Test Order code: 4546 Preferred specimen: Gynecological sample collected in SurePath collection fluid. Collection: Obtain an adequate sample using a broom-like detachable device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Separate the broom part of the device from the handle and place the broom into the collection vial. Cap the vial tightly and shake. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Minimum specimen: 10 mL preservative with specimen and collection device. Unacceptable: Specimens not collected in a SurePath collection vial. Specimens more than 28 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Unit code: 604544 Ref range: By report Reported: Within 7 days Cytology, SurePath Pap with ASC Reflex HPV, High Risk ONLY Order code: 4555 Preferred specimen: Gynecological sample collected in SurePath collection fluid. Collection: Obtain an adequate sample using a broom-like detachable device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Separate the broom part of the device from the handle and place the broom into the collection vial. Cap the vial tightly and shake. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Minimum specimen: 10 mL preservative with specimen and collection device. Notes: Specimen will be reflexed to High Risk HPV testing when cytologic specimen is interpreted with Atypical Squamous Cells. Unacceptable: Specimens not collected in a SurePath collection vial. Specimens more than 28 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Pap Test: Routine Cytopathologic Evaluation HPV: Nucleic Acid Probe Unit code: 604555 Ref range: By report Reported: Within 7 days Cytology, SurePath Pap with HPV, High Risk S1 0 Order code: 4560 Preferred specimen: Gynecological sample collected in SurePath collection fluid. Collection: Obtain an adequate sample using a broom-like detachable device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Separate the broom part of the device from the handle and place the broom into the collection vial. Cap the vial tightly and shake. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Minimum specimen: 10 mL preservative with specimen and collection device. Notes: Test includes SurePath Pap test and Human Papillomavirus (HPV), High Risk. Unacceptable: Specimens not collected in a SurePath collection vial. Specimens more than 28 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Pap Test: Routine Cytopathologic Evaluation HPV: Nucleic Acid Probe Unit code: 604560 CPT Code(s): 87621 Ref range: By report Reported: Within 7 days Test List 10-166 BBPL Directory of Services Cytology, SurePath Pap with Reflex HPV, High and Low Risk Order code: 4550 Preferred specimen: Gynecological sample collected in SurePath collection fluid. Collection: Obtain an adequate sample using a broom-like detachable device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Separate the broom part of the device from the handle and place the broom into the collection vial. Cap the vial tightly and shake. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Minimum specimen: 10 mL preservative with specimen and collection device Notes: Specimen will be reflexed to High and Low HPV testing when original cytologic specimen is interpreted with Atypical Squamous Cells or as Low Grade Squamous Intraepithelial Lesion Unacceptable: Specimens not collected in a SurePath collection vial. Specimens more than 28 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Pap Test: Routine Cytopathologic Evaluation HPV: Nucleic Acid Probe Unit code: 604550 Ref range: By report Reported: Within 7 days Cytology, SurePath Pap with Reflex HPV, High Risk ONLY Order code: 4551 Preferred specimen: Gynecological sample collected in SurePath collection fluid. Collection: Obtain an adequate sample using a broom-like detachable device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Separate the broom part of the device from the handle and place the broom into the collection vial. Cap the vial tightly and shake. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Minimum specimen: 10 mL preservative with specimen and collection device. Notes: Specimen will be reflexed to High Risk HPV testing when cytologic specimen is interpreted with Atypical Squamous Cells or as Low Grade Squamous Intraepithelial Lesion. Unacceptable: Specimens not collected in a SurePath collection vial. Specimens more than 28 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Pap Test: Routine Cytopathologic Evaluation HPV: Nucleic Acid Probe S1 0 Unit code: 604551 Ref range: By report Reported: Within 7 days Cytology, ThinPrep Liquid-Based Pap Test Order code: 4545 Preferred specimen: Gynecological sample collected in ThinPrep collection fluid. Collection: Obtain an adequate sample using a broom-like device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Rinse the collection device in the PreservCyt solution by rotating the device vigorously in the solution 10 times. Discard the collection device. Cap the vial tightly. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Unacceptable: Specimens not collected in a ThinPrep collection vial. Specimens more than 21 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Unit code: 604545 Ref range: By report Reported: Within 7 days 10-167 Test List BBPL Directory of Services Cytology, ThinPrep Pap with HPV, High Risk Order code: 4570 Preferred specimen: Gynecological sample collected in ThinPrep collection fluid. Collection: Obtain an adequate sample using a broom-like device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Rinse the collection device in the PreservCyt solution by rotating the device vigorously in the solution 10 times. Discard the collection device. Cap the vial tightly. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Notes: Test includes ThinPrep Pap test and Human Papillomavirus (HPV), High Risk. Unacceptable: Specimens not collected in a ThinPrep collection vial. Specimens more than 21 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Pap Test: Routine Cytopathologic Evaluation HPV: Nucleic Acid Probe Unit code: 604570 CPT Code(s): 87621 Ref range: By report Reported: Within 7 days Cytology, ThinPrep Pap with Reflex HPV, High and Low Risk Order code: 4548 Preferred specimen: Gynecological sample collected in ThinPrep collection fluid. Collection: Obtain an adequate sample using a broom-like device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Rinse the collection device in the PreservCyt solution by rotating the device vigorously in the solution 10 times. Discard the collection device. Cap the vial tightly. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Notes: Specimen will be reflexed to High and Low Risk HPV testing when cytologic specimen is interpreted with Atypical Squamous Cells or as Low Grade Squamous Intraepithelial Lesion. Unacceptable: Specimens not collected in a ThinPrep collection vial. Specimens more than 21 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Pap Test: Routine Cytopathologic Evaluation HPV: Nucleic Acid Probe Unit code: 604548 Ref range: By report S1 0 Reported: Within 7 days Cytology, ThinPrep Pap with Reflex HPV, High Risk ONLY Order code: 4549 Preferred specimen: Gynecological sample collected in ThinPrep collection fluid. Collection: Obtain an adequate sample using a broom-like device. Insert the broom into the endocervical canal, apply gentle pressure and rotate the broom in a clockwise direction five (5) times. Rinse the collection device in the PreservCyt solution by rotating the device vigorously in the solution 10 times. Discard the collection device. Cap the vial tightly. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Notes: Specimen will be reflexed to High Risk HPV testing when cytologic specimen is interpreted with Atypical Squamous Cells. Unacceptable: Specimens not collected in a ThinPrep collection vial. Specimens more than 21 days old from collection date. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Pap Test: Routine Cytopathologic Evaluation HPV: Nucleic Acid Probe Unit code: 604549 Ref range: By report Reported: Within 7 days Test List 10-168 BBPL Directory of Services Cytology, Thyroid, Fine Needle Aspiration (FNA) Order code: 4405 Preferred specimen: Collection: FNA Collection Kits and Clinical History Forms are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Refer to Fine Needle Aspiration (FNA) Specimen Collection for detailed instructions. Specimen: Aspirated cellular material from thyroid lesions/cysts submitted for evaluation and detection of malignant diseases. Fine needle aspirations should include the following three components for optimal cytologic results: Two fixed slides: Place one small drop of specimen on a glass side. Take a second glass slide and smear the drop of material. Immediately place both slides in plastic container with cytology fixative. Two air dried slides: Place one small drop of specimen on a glass slide. Take a second glass slide and smear the drop of material. Allow both slides to dry. Place air dried slides in plastic cytology transport container. Remaining Fluid: The remaining fluid is submitted in a cytology container with equal amount of CytoRich fixative. After the direct smears have been prepared, the needle is removed from the syringe. The syringe is used to draw up the cytology fixative fluid and then expel the remaining specimen into the cytology container. The lid must be placed on tightly for shipping to the laboratory. Notes: The frosted end of the microscopic slides and collection containers must be labeled with two (2) person specific identifiers and detailed specimen information (e.g., left upper lobe, thyroid). Submit specimen with a completed Cytology request and Clinical History Form. Unacceptable: Syringes with or without needles. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Room temperature Method: Routine Cytopathologic Evaluation Reporting: The Bethesda System for Thyroid Cytopathology Unit code: 604405 CPT Code(s): 88173 Reported: 1-2 days Cytology, Urine Order code: 4075 Preferred specimen: 30 mL of fresh urine, bladder washing, or urethral drainage submitted in a 90 mL specimen container with an equal volume of cytology fixative (30 mL CytoRich). Transport at room temperature. Voided urine should be collected sometime after the first morning urination or 3-4 hours after the patient has last urinated. Cells held overnight in the bladder may be degraded, making them difficult to analyze in the laboratory. Notes: The specimen must be labeled with two (2) person specific identifiers and specimen source. Submit specimen with a completed Cytology test request form that includes clinicial history and appropriate ICD9 code(s). Other acceptable: Urine without cytology fixative that has been refrigerated. S1 0 Unacceptable: Specimens improperly labeled. Specimens submitted in expired collection reagent. 24-hour urine collection (for kidney diagnostics). Transport temp: Urine with fixative: Room temperature Urine without fixative: Refrigerated Method: Routine Cytopathologic Evaluation Unit code: 604075 CPT Code(s): 88112 Ref range: By report Reported: 1-2 days Cytology, Urine with Reflex to Urovysion Order code: 4070 Preferred specimen: 60 mL fresh urine collected into a sterile specimen container. Voided urine should be collected sometime after the first morning urination or 3-4 hours after the patient has last urinated. Cells held overnight in the bladder may be degraded, making them difficult to analyze in the laboratory. Immediately after collection, add 60 mL of the voided urine into a Urine Specimen Preservative container (contains 30 mL PreservCyt Solution). Secure the lid tightly and refrigerate ASAP. Urine preservative transport kits with handling instructions are available through BBPL Client Services. The specimen must be labeled with two (2) person specific identifiers and submitted with a completed Cytology test request form. Minimum specimen: 60 mL urine Notes: Urine Cytology will be reflexed to Urovysion when the cytologic specimen is interpreted as Negative for Malignancy. Other acceptable: Fresh urine (min: 60 mL) in a sterile specimen container mixed with urine cytology fixative (alcohol based). Add equal volume of fixative to urine (1:1 ratio). Urine must be fixed immediately after collection and refrigerated. Unacceptable: Specimens without fixative. Specimens improperly labeled. Specimens submitted in expired collection reagent. Transport temp: Refrigerated Method: Urine Cytology: Routine Cytopathologic Evaluation Urovysion: Fluorescence in situ Hybridization Unit code: 604070 CPT Code(s): 88112 Ref range: By report Reported: 2-7 days 10-169 Test List BBPL Directory of Services Cytomegalovirus Antibody, IgG Order code: 3533 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Label specimens as "acute" or "convalescent". Convalescent specimen should be collected at least 10 days after the acute specimen. Unacceptable: Severely hemolyzed, lipemic, icteric, contaminated or heat-inactivated specimens. Transport temp: Refrigerated. Freeze serum specimens if not shipped to laboratory within 48 hours after collection. Method: Enzyme Immunoassay Unit code: 353030 CPT Code(s): 86644 Ref range: <0.80 IV: Negative - No IgG antibody to CMV detected. 0.80-0.99 IV: Equivocal - Suggest repeat testing in 10-14 days. >0.99 IV: Positive - IgG antibody to CMV detected indicative of current or past infection. Reported: 1-5 days Cytomegalovirus Antibody, IgG & IgM Order code: 3539 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: Label specimens as "acute" or "convalescent". Convalescent specimen should be collected at least 10 days after the acute specimen. Unacceptable: Severely hemolyzed, lipemic, icteric, contaminated or heat-inactivated specimens. Transport temp: Refrigerated. Freeze serum specimens if not shipped to laboratory within 48 hours after collection. Method: Enzyme Immunoassay Unit code: 353029 CPT Code(s): 86644, 86645 Ref range: Cytomegalovirus Antibody IgG: <0.80 IV: Negative - No IgG antibody to CMV detected. 0.80-0.99 IV: Equivocal - Suggest repeat testing in 10-14 days. >0.99 IV: Positive - IgG antibody to CMV detected indicative of current or past infection. Cytomegalovirus Antibody IgM: <0.90 IV: Negative - No IgM antibody to CMV detected. 0.90-1.09 IV: Equivocal - Suggest repeat testing in 10-14 days. >1.09 IV: Positive - IgM antibody to CMV detected indicative of current or past infection. S1 0 Reported: 1-5 days Cytomegalovirus Antibody, IgM Order code: 3531 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Label specimens as "acute" or "convalescent". Convalescent specimen should be collected at least 10 days after the acute specimen. Unacceptable: Severely hemolyzed, lipemic, icteric, contaminated or heat-inactivated specimens. Transport temp: Refrigerated. Freeze serum specimens if not shipped to laboratory within 48 hours after collection. Method: Enzyme Immunoassay Unit code: 353031 CPT Code(s): 86645 Ref range: <0.90 IV: Negative - No IgM antibody to CMV detected. 0.90-1.09 IV: Equivocal - Suggest repeat testing in 10-14 days. >1.09 IV: Positive - IgM antibody to CMV detected indicative of current or past infection. Reported: 1-5 days Cytomegalovirus, Qualitative PCR Order code: 38150 Preferred specimen: 1.0 mL plasma, lavender (EDTA) or light blue (sodium citrate) top tube. Remove plasma from cells within 6 hours after collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Indicate source on test request form. Minimum specimen: 0.5 mL plasma or CSF. Other acceptable: 1.0 mL CSF in a sterile container, frozen. Unacceptable: Serum, whole blood, heparinized plasma, or bone marrow. Transport temp: Frozen Method: Polymerase Chain Reaction Unit code: 538150 CPT Code(s): 87496 Ref range: By report Reported: 1-7 days Test List 10-170 BBPL Directory of Services Cytomegalovirus, Quantitative PCR Order code: 38155 Preferred specimen: 1.0 mL plasma, lavender (EDTA) or light blue (sodium citrate) top tube. Remove plasma from cells within 6 hours after collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Indicate source on test request form. Minimum specimen: 0.5 mL plasma or CSF. Other acceptable: 1.0 mL CSF in a sterile container, frozen. Unacceptable: Serum, whole blood, heparinized plasma, or bone marrow. Transport temp: Frozen Method: Polymerase Chain Reaction Unit code: 538155 CPT Code(s): 87497 Ref range: By report Reported: 1-7 days Cytoplasmic Neutrophil Antibodies, Serum See: Anti-Neutrophil Cytoplasmic Antibodies D-Dimer Order code: 2272 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube. Light blue top tube must be completely filled to ensure proper blood to anticoagulant ratio (9:1). Mix tube immediately by gentle inversion. Remove plasma from cells ASAP, transfer into a plastic transport tube and freeze. Separate specimens must be submitted when multiple test are ordered. Minimum specimen: 0.5 mL platelet-poor plasma Other acceptable: 3.2% sodium citrate whole blood or plasma at room temperature or refrigerated. Specimens must be received in the laboratory within 24 hours of collection. Unacceptable: Serum. Specimens collected in anticoagulants other than 3.2% sodium citrate. Frozen whole blood or any non-frozen specimen greater than 24 hours old. Transport temp: Frozen Method: Latex Enhanced Immunoassay Unit code: 202720 CPT Code(s): 85379 Ref range: <230 ng/mL S1 0 Reported: Within 24 hours Dantrium See: Dantrolene Dantrolene Order code: 81154 Preferred specimen: 2.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells and transfer to a plastic amber transport tube. Minimum specimen: 0.3 mL serum or plasma Notes: Protect from light during collection, storage, and shipment. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. Other acceptable: 2.0 mL plasma, lavender top tube (EDTA). Remove plasma from cells and transfer to a plastic amber transport tube. Unacceptable: Separator tubes and gels. Specimens not protected from light. Transport temp: Refrigerated Method: Spectrofluorometry Unit code: 811540 CPT Code(s): 80299 Ref range: By report Reported: 3-8 days Dapotum See: Fluphenazine Datril See: Acetaminophen 10-171 Test List BBPL Directory of Services Dehydroepiandrosterone (DHEA) Order code: 82130 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Notes: Collect specimen between 6-10 AM Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) or lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 811750 CPT Code(s): 82626 Ref range: Reported: 1-4 days Dehydroepiandrosterone (DHEA) Sulfate Order code: 1118 Preferred specimen: 1.0 mL serum, red top or gel-barrier tube. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.2 mL serum or plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) or lavender (EDTA) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Unacceptable: Hemolyzed specimens. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 111080 CPT Code(s): 82627 Ref range: Male: 80-560 µg/dL Female: 35-430 µg/dL Reported: 1-3 days Delta-Aminolevulinic Acid S1 0 See: Aminolevulinic Acid Demerol See: Meperidine and Metabolite Deoxycortisol See: 11-Deoxycortisol Quantitative Deoxypyridinoline Crosslinks Order code: 81106 Preferred specimen: 3.5 mL aliquot from a well-mixed, first morning urine in a plastic transport tube, frozen. Minimum specimen: 0.5 mL urine aliquot Transport temp: Frozen Method: Quantitative Enzyme Immunoassay Unit code: 811605 CPT Code(s): 82523 Ref range: Deoxypyridinoline: Adult Male: 2.3-8.7 nM/mM Premenopausal Adult Female: 3.1-8.7 nM/mM The target value for treated postmenopausal adult females is the same as the premenopausal reference interval. Reported: 1-8 days Depakene See: Valproic Acid, Total Depakote See: Valproic Acid, Total Test List 10-172 BBPL Directory of Services Desipramine Order code: 82120 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: For therapeutic monitoring, collect specimen immediately prior to next dose (minimum 12 hours after last dose). If imipramine has been administered, order Imipramine and Desipramine (order code 83490). Other acceptable: 1.0 mL plasma, lavender ( EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood. Gel separator tubes or gels. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 811700 CPT Code(s): 80160 Ref range: Therapeutic: 100-300 ng/mL Toxic: >500 ng/mL Reported: 1-5 days Desmethylclomipramine See: Clomipramine & Metabolite Desmethylmethsuximide See: Methsuximide & Normethsuximide Desyrel See: Trazodone Dexamethasone Order code: 87110 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells within 1 hour of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple test are ordered. S1 0 Minimum specimen: 1.0 mL serum or plasma Other acceptable: 3.0 mL plasma, lavender (EDTA) or green (lithium or sodium heparin) top tube. Remove plasma from cells within 1 hour of collection, transfer to a plastic transport tube and freeze. Transport temp: Frozen Method: HPLC Tandem Mass spectrometry Unit code: 811710 CPT Code(s): 82542 Ref range: Adult Baseline: less than 30 ng/dL 8:00 AM sample following 1 mg Dexamethasone, previous evening: 140-295 ng/dL 8:00 AM sample following 8 mg Dexamethasone, (4 x 2 mg doses) previous day: 1600-2850 ng/dL Reported: 3-9 days DHEA See: Dehydroepiandrosterone (DHEA) DHEA-S See: Dehydroepiandrosterone (DHEA) Sulfate 10-173 Test List BBPL Directory of Services Diazepam & Nordiazepam Order code: 85920 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Test includes: Diazepam and Nordiazepam. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Gas Chromatography Unit code: 840950 CPT Code(s): 80154 (x2) Ref range: Diazepam: 0.2-1.0 µg/mL - Based on normal dosage amounts. Nordiazepam: 0.1-1.5 µg/mL - Based on normal dosage amounts. Toxic: Great than 2.5 µg/mL Reported: 1-5 days Differential, Manual Order code: 2035 Preferred specimen: One well-mixed lavender (EDTA) top tube and two unstained whole blood smears. Smears should be prepared within 4-6 hours after specimen is collected. Minimum specimen: One EDTA tube 1/2 full or two whole blood smears Other acceptable: Lavender top microtainer (EDTA) with 0.5 mL blood. Unacceptable: Clotted or frozen specimens. Transport temp: Room temperature Method: Microscopic Examination Unit code: 94250 CPT Code(s): 85007 Ref range: Segs: 39-79% Bands: 0-12% Lymphs: 20-52% Monos: 0-10% Eos: 0-6% Baso: 0-2% Reported: Within 24 hours S1 0 Digitaline See: Digitoxin Digitoxin Order code: 82150 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: This test will not measure digoxin (Lanoxin, Digitek); order 1150 for digoxin testing. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Fluorescence Polarization Immunoassay Unit code: 811900 CPT Code(s): 80299 Ref range: Therapeutic Range: 10.0-32.0 ng/mL Toxic: > 35.0 ng/mL Reported: 1-4 days Test List 10-174 BBPL Directory of Services Digoxin Order code: 1150 Preferred specimen: 0.5 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 0.2 mL serum Notes: Collect 6-8 hours after last oral dose. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 110020 CPT Code(s): 80162 Ref range: Therapeutic: 0.5-2.0 ng/mL Potentially Toxic: >4.0 ng/mL Reported: Within 24 hours Dihydrotestosterone See: 5-a-Dihydrotestosterone Dilantin See: Phenytoin Serum Phenytoin Free Dilute Russell Viper Venom Time (dRVVT) with Reflex to dRVVT 1:1 Mix & Confirmation Order code: 81196 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: If dRVVT is elevated, then dRVVT 1:1 mix will be added. If the dRVVT 1:1 mix is elevated, then the dRVVT confirmation test will be added. Additional charges apply. Unacceptable: Serum, EDTA plasma, or hemolyzed specimens. S1 0 Transport temp: CRITICAL FROZEN Method: Electromagnetic Mechanical Clot Detection Unit code: 811960 CPT Code(s): 85613 Ref range: Dilute Russell Viper Venom Time (dRVVT): 33-44 seconds Dilute Russell Viper Venom (dRVVT) 1:1 Mix (performed if dRVVT > 44 seconds): 33-44 seconds Dilute Russell Viper Venom Time (dRVVT) Confirmation Test (performed if dRVVT 1:1 Mix > 44 seconds): Negative Reported: 1-2 days Diphenhydramine Order code: 82170 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 0.4 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 812050 CPT Code(s): 80299 Ref range: By report Reported: 3-6 days 10-175 Test List BBPL Directory of Services Diphtheria & Tetanus Antibodies, IgG Order code: 82101 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: "Pre" and "post" vaccination specimens should be submitted for testing. "Post" specimens should be drawn 30 days after immunization. Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine". If shipped separately, "post" specimen must be received within 60 days of "pre" specimen. Unacceptable: Plasma or other body fluids. Transport temp: Refrigerated Method: Quantitative Multiplex Bead Assay Unit code: 812101 CPT Code(s): 86317 (x2) Ref range: Antibody concentrations of >0.1 IU/mL are usually considered protective for diphtheria or tetanus. Reported: 1-2 days Diphtheria Antitoxoid, Serum Order code: 82180 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: "Pre" and "post" vaccination specimens must be submitted together for testing. "Post" specimens should be drawn 30 days after immunization. Mark specimens clearly as "pre-vaccine" or "post-vaccine" . If shipped separately, post specimen must be received within 60 days of "pre" specimen. Unacceptable: Plasma or other body fluids. Transport temp: Refrigerated Method: Semi-Quantitative Multi-Analyte Fluorescent Detection Unit code: 812100 CPT Code(s): 86317 Ref range: Antibody concentration of > 0.1 IU/mL is usually considered protective. Reported: 1-4 days S1 0 Direct Bilirubin See: Bilirubin, Direct Disopyramide Order code: 82190 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Immunoassay Unit code: 812200 CPT Code(s): 80299 Ref range: Therapeutic Range: 2.0-5.0 µg/mL Toxic: > 7.0 µg/mL Reported: 1-5 days Diuretic Hormone See: Arginine Vasopressin Diuretic Survey, Urine Order code: 81223 Preferred specimen: 10.0 mL random urine with no preservatives. Minimum specimen: 1.2 mL urine Transport temp: Refrigerated Method: Qualitative High Performance Liquid Chromatography/Ultraviolet Detection Unit code: 812230 CPT Code(s): 82486 Ref range: By report Reported: 5-14 days Test List 10-176 BBPL Directory of Services DNA Cell Cycle Analysis, Paraffin Block (Breast) Order code: 35125 Preferred specimen: Paraffin embedded breast tissue block. For multiple samples, submit a separate test request form with each sample. Please submit a copy of the pathology report. Notes: Includes: Ploidy and S Phase Transport temp: Room temperature Method: Image Analysis Unit code: 535125 CPT Code(s): 88358 Ref range: By report Reported: Within 7 days DNA Cell Cycle Analysis, Paraffin Block (Non-Breast) Order code: 35100 Preferred specimen: Paraffin embedded non-breast tissue. For multiple samples, submit a separate test request form with each sample. Please submit a copy of the pathology report. Minimum specimen: 2 pre-cut tissue slides Notes: Includes Ploidy and S Phase Transport temp: Room temperature Method: Image Analysis Unit code: 535100 CPT Code(s): 88358 Ref range: By report Reported: 2-9 days DNA, Double Stranded, Antibody See: dsDNA Antibody, IgG DNA, Single-Stranded, Antibody See: ssDNA Antibody, IgG S1 0 Doxepin & Metabolite Order code: 82220 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray ( sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 812450 CPT Code(s): 80166, 80299 Ref range: Therapeutic Range: Total (Doxepin & Nordoxepin): 100-300 ng/mL Toxic Level: Greater than 500 ng/mL Reported: 1-5 days DPD 5-Fluorouracil Toxicity Order code: 81247 Preferred specimen: 7.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Notes: This procedure will only detect the presence of the wild type or mutant allele for the DPD IVS14+1G>A mutation. Unacceptable: Hemolyzed or frozen specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction (PCR); Restriction Enzyme Digestion; Gel Electrophoresis Unit code: 812470 CPT Code(s): 81400 Ref range: By report Reported: Within 7 days Dramamine See: Diphenhydramine 10-177 Test List BBPL Directory of Services Drsmethylclomipramine See: Clomipramine & Metabolite Drug Abuse Screen 10 UMC COC Order code: 81275 Preferred specimen: 50 mL random urine specimen in a clean plastic container. Minimum specimen: 15 mL urine Notes: UMC Chain of Custody requisition is required for testing. Includes: Amphetamines Barbituates Benzodiazepines Cannabinoids Cocaine Methadone Methaqualone Opiates PCP Propoxyphene Transport temp: Refrigerated Unit code: 812705 CPT Code(s): 80101 (x10) Ref range: By report Reported: 1-2 days Drug Abuse Screen 5 UMC COC Order code: 82228 Preferred specimen: 50 mL random urine specimen in a clean plastic container. Minimum specimen: 15 mL urine Notes: UMC Chain of Custody requisition is required for testing. Includes: Amphetamines Cannabinoids Cocaine Opiates Phencyclidine-PCP Transport temp: Refrigerated S1 0 Unit code: 812550 CPT Code(s): 80101 (x5) Ref range: By report Reported: 1-2 days Drug Abuse Screen 7 UMC COC Order code: 82229 Preferred specimen: 50 mL random urine sample. Minimum specimen: 15 mL random urine Notes: UMC Chain of Custody requisition is required for testing. Includes: Amphetamines Barbituates Benzodiazepines Cannabinoids Cocaine Opiates Phencyclidine-PCP Transport temp: Refrigerated Unit code: 812600 CPT Code(s): 80101 (x7) Ref range: By report Reported: 1-2 days Test List 10-178 BBPL Directory of Services Drug Abuse Screen 8 UMC Order code: 82230 Preferred specimen: 50 mL random urine sample. Minimum specimen: 15 mL urine Notes: For clinical (medical) or forensic purposes. UMMC Chain of Custody requisition is required for forensic testing. Includes: Amphetamines Barbituates Benzodiazepines Cannabinoids Cocaine Ethanol Opiates Phencyclidine-PCP Transport temp: Refrigerated Unit code: 812650 CPT Code(s): 80101 (x8) Ref range: By report Reported: 1-2 days Drug Abuse Screen 8, Pre-employment-UMC COC Order code: 82231 Preferred specimen: 50 mL random urine sample. Minimum specimen: 15 mL random urine Notes: UMC Chain of Custody requisition is required. Includes: Amphetamines Barbituates Benzodiazepines Cannabinoids Cocaine Ethanol Opiates Phencyclidine- PCP Transport temp: Refrigerated Unit code: 812655 CPT Code(s): 80100 (x8) Ref range: By report S1 0 Reported: 1-2 days Drug Confirmation, Single Analyte, Urine Order code: 82233 Preferred specimen: 50 mL random urine specimen in a clean plastic container. For clinical (medical) or forensic purposes. UMMC Chain of Custody requisition is required for forensic testing. Minimum specimen: 15 mL urine Transport temp: Refrigerated Unit code: 812900 CPT Code(s): 80102 Ref range: By report Drug Confirmation/Quantitation - Fentanyl & Metabolite, Serum or Plasma Order code: 82525 Preferred specimen: 4.0 mL serum, red top tube. Remove serum from cells ASAP and transfer to a plastic transport tube. Do not collect in SST. Minimum specimen: 2.0 mL serum or plasma Notes: Drugs covered: fentanyl and metabolite (norfentanyl). Positive cutoff: 0.1 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 4.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 812520 CPT Code(s): 83925 Ref range: By report Reported: 1-4 days 10-179 Test List BBPL Directory of Services Drug Confirmation/Quantitation - Methadone & Metabolite, Serum or Plasma Order code: 84205 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Drugs covered: methadone and EDDP (methadone metabolite). Positive cutoff: 10 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 1.0 mL plasma, gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Serum separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 826350 CPT Code(s): 83840 Ref range: By report Reported: 1-4 days Drug Confirmation/Quantitation - Opiates, Serum or Plasma Order code: 81252 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Drugs covered: codeine, morphine, 6-acetylmorphine, hydrocodone, hydromorphone, oxycodone and oxymorphone. All drugs covered are the non-glucuronidated (free) form. Positive cutoff: 2 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tube. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry S1 0 Unit code: 812525 CPT Code(s): 83925 Ref range: By report Reported: 1-4 days Drug Detection Panel by High-Resolution Time-of-Flight Mass Spectrometry, Umbilical Cord Tissue Order code: 81306 Preferred specimen: Collect at least 6 inches of umbilical cord (approximately the length of an adult hand). Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or sterile water. Pat the cord dry and place in container for transport. Minimum specimen: 6 inches of umbilical cord Notes: Testing is for medical purposes only. Drugs covered: Opioids, Stimulants, Sedative-hypnotics, Cannabinoids (11-nor-9-carboxy-THC), and Phencyclidine (PCP). Detection of drugs in umbilical cord tissue is intended to reflect maternal drug use during pregnancy. The pattern and frequency of drug(s) used by the mother cannot be determined by this test. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drugs in umbilical cord tissue depends on extent of maternal drug use, as well as drug stability, unique characteristics of drug deposition in umbilical cord tissue, and the performance of the analytical method. Drugs administered during labor and delivery may be detected. Detection of drugs in umbilical cord tissue does not insinuate impairment and may not affect outcomes for the infant. Unacceptable: Cords soaking in blood or other fluid. Tissue that is obviously decomposed. Transport temp: Refrigerated Method: Qualitative Liquid Chromatography-Time of Flight Mass Spectrometry/Qualitative Enzyme-Linked Immunosorbent Assay. Unit code: 813066 CPT Code(s): 80100 (x2) Ref range: By report Reported: 1-5 days Test List 10-180 BBPL Directory of Services Drug Profile, Blood (8 Drugs) Order code: 81603 Preferred specimen: 7.0 mL whole blood, gray (sodium fluoride) top tubes. Minimum specimen: 3.0 mL whole blood Notes: Testing includes amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine and metabolite, opiates, oxycodone, phencyclidine. If specimen is positive confirmation testing will be performed at no addtional charge. Order only for medical purposes, not for forensic use or workplace testing. Other acceptable: 7.0 mL whole blood, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Serum, plasma, or clotted blood. Transport temp: Refrigerated Method: Immunoassay/Mass Spectrometry Unit code: 812603 CPT Code(s): 80101 (x8) Ref range: By report Reported: 7-9 days Drug Profile, Urine (10 Drugs) Order code: 82704 Preferred specimen: 50 mL random urine in a plastic urine container. No chain of custody form required. Profile is designed for pain management (clinical drug monitoring) and is not intended for workplace testing. Minimum specimen: 50 mL urine Notes: Test includes: Amphetamine, Barbiturate, Benzodiazepines, Cannabinoid, Cocaine, Methadone, Opiates, Oxycodone/Oxymorphone, Phencyclidine, and Propoxyphene. If screen is positive, confirmation testing will be performed at an additional charge. Transport temp: Room temperature Method: Immunoassay/Mass Spectrometry Unit code: 812704 CPT Code(s): 80101 (x10) Ref range: By report Reported: 2-8 days Drug Screen (DOT)-5 Panel with 6-am and Ecstasy CRL COC S1 0 Order code: 82556 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL Federal drug testing chain of custody documentation is required. Follow standardize collection procedures for the Federally regulated Drug Testing program. Urine collection must take place in a collection site meeting the requirements for DOT testing. Refer to the BBPL Patient Service Center Locator for a drug collection site. Minimum specimen: 20 mL Notes: Test includes: Amphetamine, Cocaine, Marijuana, Opiates, Phencyclidine (PCP), 6-Acetylmorphine and Ecstasy. Urine test results are evaluated by a Medical Review Officer (MRO). Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812556 CPT Code(s): 80101 (x5) Reported: 2-5 days Drug Screen Bath Salts, Urine CRL COC Order code: 82631 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812631 CPT Code(s): 80101 Reported: 1-5 days Drug Screen K2 (Synthetic Cannabis) CRL COC Order code: 82632 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812632 CPT Code(s): 82541 Reported: 1-5 days 10-181 Test List BBPL Directory of Services Drug Screen, Comprehensive UMC Order code: 82235 Preferred specimen: 50 mL random urine sample. Minimum specimen: 15 mL urine Notes: For clinical (medical) or forensic purposes. UMC Chain of Custody requisition is required for forensic testing. This screen involves an exhaustive approach to qualitative identification and is designed to identify several hundred drug compounds and their metabolites. The drugs listed below do not represent a complete list, but rather, the broad categories of drugs screened. Amines/Stimulants: Amphetamine Methamphetamine Caffeine Ephedrine Chlorpheniramine Tripelennamine Phenylpropanolamine Phentermine Cocaine Diethylpropion Barbiturates: Amobarbital Butabarbital Secobarbital Barbital Pentobarbital Butalbital Phenobarbital Narcotics: Morphine Meperidine Methadone Hydrocodone Dihydrocodeine Codeine Pentazocine Oxycodone Propoxyphene Hydromorphone Antidepressants: Amitriptyline Imipramine Doxepin Loxapine Cyclobenzaprine Nortriptyline Desipramine Amoxapine Trazodone Sedatives/Hypnotics/Tranquilizers: Chlordiazepoxide Meprobamate Flurazepam Methaqualone Glutethimide Carisoprodol Diphenhydramine Hydroxyzine Pyrilamine Temazepam Diazepam Lorazepam Oxazepam Ethchlorvynol Chlorazepate Doxylamine Methyprylon Phenothiazines (includes Thioridazine, Chlorpromazine, Trifluoperazine, Triflupromazine, etc.) S1 0 Transport temp: Refrigerated Unit code: 812800 CPT Code(s): 80101 (x10), 83788 (x2) Ref range: By report Reported: 1-2 days Drug Screen, Meconium Order code: 82241 Preferred specimen: All meconium (blackish material) from newborn's first excretion in leak-proof container. Minimum specimen: 1.0 g meconium Notes: Includes: amphetamines, barbiturates, cannabinoids (marijuana), cocaine, and opiates. Transport temp: Refrigerated Method: Immunoassay/Gas Chromatography/Mass Spectrometry Unit code: 813060 CPT Code(s): 80101 (x4) Ref range: By report Reported: 1-2 days Drug Screen, Single Analyte, Urine UMC Order code: 82234 Preferred specimen: 20 mL random urine Minimum specimen: 15 mL urine Notes: Qualitative urine assay designed for the identification of a single drug. Indicate drug to be tested on test request form. Transport temp: Refrigerated Unit code: 813100 CPT Code(s): 80299 Ref range: By report Reported: Varies Test List 10-182 BBPL Directory of Services Drug Screen-10 Panel + Alcohol CRL COC Order code: 82718 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Alcohol, Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Marijuana, Methadone, Methaqualone, Opiates, Phencyclidine (PCP), and Propoxyphene. Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812718 CPT Code(s): 80101 (x11) Reported: 1-5 days Drug Screen-10 Panel CRL COC Order code: 81276 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Marijuana, Methadone, Methaqualone, Opiates, Phencyclidine and (PCP), Propoxyphene. Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812706 CPT Code(s): 80101 (x10) Reported: 1-5 days Drug Screen-11 Panel CRL COC Order code: 81278 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amitriptyline/Nortriptyline, Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Marijuana, Methadone, Opiates, Oxycodone, Phencyclidine, and Propoxyphene. Transport temp: Room temperature S1 0 Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812708 CPT Code(s): 80101 (x11) Reported: 1-5 days Drug Screen-13 Panel CRL COC Order code: 82714 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Alcohol, Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Ketamine, Marijuana, Meprobamate, Merperidine, Methadone, Opiates, Oxycodone, and Phencyclidine (PCP). Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812714 CPT Code(s): 80101 (x13) Reported: 1-5 days Drug Screen-14 Panel CRL COC Order code: 81697 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Alcohol, Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Ketamine, Marijuana, Meperidine, Meprobamate, Methadone, Opiates, Oxycodone, Propoxyphene, and Tramadol. Transport temp: Room Temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812697 CPT Code(s): 80101 (x14) Reported: 1-5 days 10-183 Test List BBPL Directory of Services Drug Screen-16 Panel CRL COC Order code: 81277 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Alcohol, Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Fentanyl, Ketamine/Norketamines, Marijuana, Meperidine, Meprobamate, Methadone, Opiates, Oxycodone/Oxymorphone, Phencyclidine (PCP), Propoxyphene, and Tramadol. Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812707 CPT Code(s): 80101 (x16) Reported: 1-5 days Drug Screen-5 Panel CRL COC Order code: 81254 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amphetamine, Cocaine, Marijuana, Opiates, and Phencyclidine (PCP). Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812549 CPT Code(s): 80101 (x5) Reported: 1-5 days Drug Screen-7 Panel CRL COC Order code: 81264 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Marijuana, Opiates, and Phencyclidine (PCP). Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) S1 0 Unit code: 812649 CPT Code(s): 80101 (x7) Reported: 1-5 days Drug Screen-8 Panel + Ecstasy CRL COC Order code: 81298 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Ecstasy, Marijuana, Opiates, Phencyclidine (PCP), and Propoxyphene. Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812698 CPT Code(s): 80101 (x9) Reported: 1-5 days Drug Screen-8 Panel CRL COC Order code: 81265 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Alcohol, Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Marijuana, Opiates, and Phencyclidine (PCP). Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812656 CPT Code(s): 80101 (x8) Reported: 1-5 days Test List 10-184 BBPL Directory of Services Drug Screen-9 Panel + Alcohol CRL COC Order code: 82648 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Alcohol, Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Ecstasy, Marijuana, Opiates, Oxycodone, and Phencyclidine (PCP). Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812648 CPT Code(s): 80101 (x10) Reported: 1-5 days Drug Screen-9 Panel + Oxycodone CRL COC Order code: 82647 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Marijuana, Methadone, Opiates, Oxycodone, Phencyclidine (PCP), and Propoxyphene. Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812647 CPT Code(s): 80101 (x10) Reported: 1-5 days Drug Screen-9 Panel CRL COC Order code: 81299 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Marijuana, Methadone, Opiates, Phencyclidine (PCP), and Propoxyphene. Transport temp: Room temperature S1 0 Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812699 CPT Code(s): 80101 (x9) Reported: 1-5 days Drug Sscreen-10 Panel + MDMA/Oxycodone CRL Order code: 82717 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Notes: Test includes: Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Ectasy, Marijuana, Methadone, Methaqualone, Opiates, Oxycodone, Phencyclidine, and Propoxyphene. Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 812717 Reported: 1-5 days 10-185 Test List BBPL Directory of Services Drugs of Abuse 9 Panel Screen, Plasma or Serum - Immunoassay Screen with Reflex to Mass Spectrometry Confirmation/Quantitation Order code: 88500 Preferred specimen: 4.0 mL plasma, gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP. Plasma is preferred over serum. Cocaine and cocaethylene are more stable in fluoride-preserved plasma than serum. Minimum specimen: 3.0 mL plasma or serum Notes: For medical purposes only; not valid for forensic use. Drugs Covered and Cutoff Concentrations: Amphetamines: Screen 30 ng/mL Barbiturates: Screen 75 ng/mL Benzodiazepines: Screen 75 ng/mL Cannabinoids: Screen 30 ng/mL Cocaine: Screen 30 ng/mL Methadone and metabolite: Screen 40 ng/mL Methamphetamine: Screen 30 ng/mL Opiates: Screen 30 ng/mL Oxycodone: Screen 30 ng/mL Phencyclidine: Screen 15 ng/mL Propoxyphene and metabolite: Screen 75 ng/mL Drugs/Drug classes reported as "Positive" are automatically reflexed to mass spectrometry confirmation/quantitation. An unconfirmed positive immunoassay screen result may be useful for medical purposes but does not meet forensic standards. The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies within a drug class. Specimens for which drugs or drug classes are detected by the screen are automaticallyreflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Other acceptable: 4.0 mL serum, red top tube. Do not draw in SST. Also plasma from lavender (EDTA) or green (sodium heparin) top tube. Unacceptable: Separator tubes. Plasma or whole blood from light blue (sodium citrate) top tube. Transport temp: Refrigerated Method: Enzyme Immunoassay/Gas Chromatography-Mass Spectrometry/Liquid Chromatography-Tandem Mass Spectrometry Unit code: 812850 CPT Code(s): 80101 (x9) Ref range: By report Reported: Screen: 1-2 days Confirmation: 1-4 days Drugs of Abuse Confirmation/Quantitation - Amphetamine, Serum or Plasma Order code: 81286 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Drugs covered: Amphetamine, methamphetamine, methylenedioxyamphetamine (MDMA), methylenedioxymethamphetamine (Ecstasy, MDA), and methylenedioxyethylamphetamine (Eve, MDA). Positive cutoff: 20 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 1.0 mL plasma, gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tube. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 812861 CPT Code(s): 82145 Ref range: By report Reported: 1-8 days Test List 10-186 S1 0 BBPL Directory of Services Drugs of Abuse Confirmation/Quantitation - Barbiturates, Serum or Plasma Order code: 82865 Preferred specimen: 3.5 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum or plasma Notes: Drugs covered: butalbital, amobarbital, pentobarbital, secobarbital, and phenobarbital. Positive cutoff: 50 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 3.5 mL plasma, lavender (EDTA), green (sodium lithium), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Serum separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tubes. Transport temp: Refrigerated Method: Quantitative Gas Chromatography/Mass Spectrometry Unit code: 812865 CPT Code(s): 82205 Ref range: By report Reported: 1-4 days Drugs of Abuse Confirmation/Quantitation - Benzodiazepines, Serum or Plasma Order code: 82870 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum or plasma Notes: Drugs covered: Alprazolam, alpha-hydroxyalprazolam, clonazepam, 7-amino-clonazepam, desalkylflurazepam, 2hydroxyethylflurazepam, diazepam, lorazepam, midazolam, nordiazepam, oxazepam, temazepam, and alpha-hydroxytriazolam. Positive cutoff: 20 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 2.0 mL plasma, gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tube. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry S1 0 Unit code: 812871 CPT Code(s): 80154 Ref range: By report Reported: 1-4 days Drugs of Abuse Confirmation/Quantitation - Cannabinoids (9-carboxy-THC), Serum or Plasma Order code: 81287 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Drugs covered: 9-carboxy-THC Positive cutoff: 5 ng/mL The drug analyte detected in this assay, 9-carboxy THC, is a metabolite of delta-9-tetrahydrocannabinol (THC). Detection of 9carboxy THC suggests use of, or exposure to, a product containing THC. This test cannot distinguish between prescribed or nonprescribed forms of THC, nor can it distinguish between active or passive use. The plasma half-life for 9-carboxy THC metabolite is estimated to range from 4-12 hours. For medical purposes only; not valid for forensic use. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium lithium), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Serum separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 812876 CPT Code(s): 82542 Ref range: By report Reported: 1-4 days 10-187 Test List BBPL Directory of Services Drugs of Abuse Confirmation/Quantitation - Cocaine Metabolite (Benzoylecgonine), Serum or Plasma Order code: 81745 Preferred specimen: 3.5 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum or plasma Notes: Drugs covered: cocaine, benzoylecgonin, m-hydroxybenzoylecgonine, and cocaethylene. Positive Cutoff: 20 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 3.5 mL plasma, lavender (EDTA), green (sodium lithium), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Serum separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tubes. Transport temp: Refrigerated Method: Quantitative Gas Chromatography/Mass Spectrometry/Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 809750 CPT Code(s): 82520 Ref range: By report Reported: 1-4 days Drugs of Abuse Confirmation/Quantitation - Phencyclidine, Serum or Plasma Order code: 82185 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Drugs covered: phencyclidine (PCP). Positive cutoff: 10 ng/mL The concentration value must be greater than or equal to the cutoff to be reported as positive For medical purposes only; not valid for forensic use. Other acceptable: 1.0 mL plasma, gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tube. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry S1 0 Unit code: 812886 CPT Code(s): 83992 Ref range: By report Reported: 1-8 days Drugs of Abuse Confirmation/Quantitation - Propoxyphene & Metabolite, Serum or Plasma Order code: 83265 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Drugs covered: Propoxyphene and metabolite (norpropoxyphene - qualitative only) Positive cutoff: 10 ng/mL For medical purposes only; not valid for forensic use. Other acceptable: 1.0 mL plasma, gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Plasma or whole blood collected in light blue (sodium citrate) top tube. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 812930 CPT Code(s): 80299 Ref range: By report Reported: 1-8 days Test List 10-188 BBPL Directory of Services dsDNA Antibody, IgG Order code: 5202 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Unacceptable: Plasma, severely hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 350115 CPT Code(s): 86225 Ref range: <25.0 IU/mL Negative 25.0-34.9 IU/mL Inconclusive 35.0-99.9 IU/mL Weakly Positive 100-200 IU/mL Moderately Positive >200 IU/mL Strongly Positive Reported: 1-3 days EBV See: Epstein-Barr Virus Antibody to Early Antigen Epstein-Barr Virus Antibody to Nuclear Antigen Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG & IgM Epstein-Barr Virus Comprehensive Profile Epstein-Barr Virus, Qualitative PCR Echinococcus Antibody, IgG Order code: 82260 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Please mark specimens plainly as "acute" or "convalescent". Unacceptable: Severely lipemic or contaminated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 813300 S1 0 CPT Code(s): 86682 Ref range: 0.00-0.89 IV: Negative - No significant level of Echinococcus IgG antibody detected. 0.90-1.09 IV: Equivocal - Questionable presence of Echinococcus IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Positive - Presence of IgG antibody to Echinococcus detected, suggestive of current or past infection. Reported: 1-5 days Echovirus Antibodies, Types 6, 7, 9, 11, 30 Order code: 82270 Preferred specimen: 3.0 mL serum, SST or red top tube. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 1.0 ml serum Notes: Acute and convalescent samples must be labeled as such; parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples. Please mark samples plainly as "acute" or "convalescent". Unacceptable: Plasma samples. Transport temp: Refrigerated Method: Serum Neutralization Assay Unit code: 813350 CPT Code(s): 86658 (x5) Ref range: Echovirus 6: Less than 1:10 Echovirus 7: Less than 1:10 Echovirus 9: Less than 1:10 Echovirus 11: Less than 1:10 Echovirus 30: Less than 1:10 Reported: 6-9 days Ecrinal See: Flecainide EGFR by FISH See: Epidermal Growth Factor Receptor (EGFR) by FISH 10-189 Test List BBPL Directory of Services EGFR by PCR See: Epidermal Growth Factor Receptor (EGFR) Mutation Analysis by PCR EGFR Mutation Analysis (PCR) with Reflex to ALK Rearrangement (FISH) Order code: 35959 Preferred specimen: Formalin-fixed, paraffin-embedded (FFPE) tissue block containing greater than 25% tumor or five 7-micron thick sections in labeled container, and one H&E reference slide. Notes: If EGFR Mutation is reported as Not Detected, then ALK Rearrangement testing will be performed at an additional charge. Testing includes pathologist's interpretation. Other acceptable: Five precut, unstained slides from paraffin block in 7-micron thick sections and one H&E reference slide. Unacceptable: Tumor block containing insufficient tumor tissue. Transport temp: Room temperature Method: Real-Time Polymerase Chain Reaction/Fluorescence in situ Hybridization Unit code: 535959 CPT Code(s): 81235, 88387, G0452 Ref range: By report Reported: 7-14 days Ehrlichia and Anaplasma Species by PCR Order code: 81366 Preferred specimen: 1.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 0.6 mL whole blood Notes: This test detects and speciates Anaplasma phagocytophilum; Ehrlichia chaffeensis; E. ewingii/E. canis; E. muris-like. The nucleic acid detected from E. ewingii and E. canis cannot be differentiated by this test. A result of "Detected" for E. ewingii/canis indicates the presence of either of these two organisms in the specimen. Unacceptable: Heparinized specimens. Transport temp: Refrigerated Method: Qualitative Polymerase Chain Reaction Unit code: 813366 CPT Code(s): 87798 (x4) Ref range: By report A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.. Reported: 1-3 days Ehrlichia Antibody Panel Order code: 85136 Preferred specimen: 0.6 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Notes: Test includes: Ehrlichia chaffeensis IgG titer; Ehrlichia chaffeensis IgM titer; human granulocytic ehrlichiosis (HGE), IgG and IgM; human monocytic ehrlichiosis (HME), IgG and IgM. Unacceptable: Hemolyzed or lipemic specimens, gross bacterial contamination. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody (IFA) Unit code: 813365 CPT Code(s): 86666 (x4) Ref range: By report Reported: 5-9 days Ehrlichia chaffeensis Antibody, IgG Order code: 82345 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within two hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.05 mL serum Notes: Acute and convalescent samples must be labeled as such; parallel testing is preferred and convalescent samples must be received within 30 days from receipt of the acute samples. Please mark sample plainly as "acute" or "convalescent". Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody Unit code: 813800 CPT Code(s): 86666 Ref range: < 1:64 Negative-No significant level of Ehrlichia chaffeensis IgG antibody detected. 1:64-1:128 Equivocal-Questionable presence of Ehrlichia chaffeensis IgG antibody detected. Repeat testing in 10-14 days may be helpful. >= 1:256 Positive-Presence of IgG antibody to Ehrlichia chaffeensis detected, suggestive of current or past infection. Reported: 1-5 days Test List 10-190 S1 0 BBPL Directory of Services Ehrlichia chaffeensis Antibody, IgM Order code: 81381 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.05 mL serum Notes: Acute and convalescent samples must be labeled as such; parallel testing is preferred and convalescent samples must be received within 30 days from receipt of the acute samples. Please mark sample plainly as "acute" or "convalescent". Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody Unit code: 813801 CPT Code(s): 86666 Ref range: < 1:16 Negative-No significant level of Ehrlichia chaffeensis IgM antibody detected. >= 1:16 Positive-Presence of IgM antibody to Ehrlichia chaffeensis detected, suggestive of current or recent infection. Reported: 1-5 days Ehrlichia chaffeensis, DNA PCR Order code: 81361 Preferred specimen: 1.0 mL whole blood, lavender (EDTA) or yellow (ACD solution A or B) top tube. Minimum specimen: 0.2 mL whole blood Unacceptable: Gross specimen contamination Transport temp: Room temperature Method: Polymerase Chain Reaction (PCR) Unit code: 813361 CPT Code(s): 87798 Ref range: Negative Reported: 2-5 days Elatrol See: Amitriptyline & Nortriptyline S1 0 Elavil, Amitriptyline & Nortriptyline, Serum See: Amitriptyline & Nortriptyline Electrolyte Panel, Serum Order code: 1028 Preferred specimen: 1.0 mL serum, SST or red top tube. Remove serum from cells ASAP; avoid hemolysis. Minimum specimen: 0.5 mL serum Notes: Test includes: Carbon Dioxide Chloride Potassium Sodium Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Ion-Selective Electrode/Enzymatic Unit code: 90060 CPT Code(s): 80051 Ref range: Carbon Dioxide Chloride Potassium Sodium 20-32 mmol/L 98-110 mmol/L 3.5-5.0 mmol/L 136-145 mmol/L Reported: Within 24 hours Electrolytes, Fecal Order code: 81377 Preferred specimen: 5 gm aliquot from well-mixed 24-hour or random stool in a clean unpreserved stool transport container. Stool must be liquid. Minimum specimen: 1 gm liquid stool Notes: Stool must be liquid. Do not add saline or water to liquefy sample. Unacceptable: Formed or viscous stool. Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 813377 CPT Code(s): 82438, 84302, 84999 Ref range: Not established Reported: 1-2 days 10-191 Test List BBPL Directory of Services Electrolytes, Urine Order code: 1054 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Includes: Chloride, Potassium, Sodium Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 102465 CPT Code(s): 82436, 84133, 84300 Ref range: Chloride Potassium Sodium 110-250 mmol/day 25-125 mmol/day 40-200 mmol/day Reported: Within 24 hours Electrophoresis, Lipoprotein See: Lipoprotein Electrophoresis Electrophoresis, Protein See: Protein Electrophoresis, CSF Protein Electrophoresis, Serum Protein Electrophoresis, Urine Elixophylin See: Theophylline Emeside See: Ethosuximide S1 0 EML4-ALK See: ALK Rearrangement by FISH ENA See: Sm/RNP Antibody, IgG Encainide Order code: 82290 Preferred specimen: 2.0 mL serum, red top tube. Remove serum from cells ASAP and FREEZE. Minimum specimen: 1.5 mL serum or plasma Notes: Separate samples must be submitted when multiple tests are ordered. Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP and FREEZE. Transport temp: CRITICAL FROZEN Method: High Performance Liquid Chromatography Unit code: 813500 CPT Code(s): 80299 Ref range: By report Reported: Within 7 days Endep See: Amitriptyline & Nortriptyline Test List 10-192 BBPL Directory of Services Endomysial Antibody, IgG Order code: 81356 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Unacceptable: Contaminated specimens Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody Unit code: 813565 CPT Code(s): 86256 Ref range: Less than 1:10 Reported: 1-8 days Entamoeba histolytica (amebiasis) Antibody, IgG Order code: 80590 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hour of collection and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent". Unacceptable: Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 802650 CPT Code(s): 86753 Ref range: 0.79 IV or less: Negative - No significant level of detectable E. histolytica IgG antibody. 0.80-1.19 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.20 IV or greater: Positive - IgG antibody to E. histolytica detected, suggestive of a current or past infection. Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done at the same time. Reported: 1-5 days Enterobius Vermicularis (Pinworm) Identification S1 0 Order code: 2345 Preferred specimen: Pinworm paddle. Gently press the sticky side of the paddle over the perianal surface. Specimen should be collected between 9 p.m. and midnight or immediately after arising in the morning. Other acceptable: Clear cellophane scotch tape. Gently press the sticky side of the tape over the perianal surface, attach the sticky side of the tape to a glass slide, and submit in a slide holder or mailer. Unacceptable: Do not use opaque or frosted (scotch) tape or slides. Do not submit on coverslips or place stool on tape or paddle. Stool specimens will not be processed. Transport temp: Room temperature Method: Microscopic Exam Unit code: 401920 CPT Code(s): 87172 Ref range: No Enterobius vermicularis identified. Reported: 1-2 days Enterovirus Antibody Panel Order code: 82310 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Test includes: Coxsackie B Virus Antibodies Poliovirus Antibodies Unacceptable: Plasma, contaminated, hemolyzed, or severly lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Serum Neutralization Unit code: 813601 CPT Code(s): 86658 (x9) Ref range: Coxsackie B1: Less than 1:10 Coxsackie B2: Less than 1:10 Coxsackie B3: Less than 1:10 Coxsackie B4: Less than 1:10 Coxsackie B5: Less than 1:10 Coxsackie B6: Less than 1:10 Poliovirus Antibodies: Less than 1:10: No detectable poliovirus antibodies. 1:10 or greater: Antibody to poliovirus detected, which may represent prior immunization or current or past infection. Reported: 6-9 days 10-193 Test List BBPL Directory of Services Enterovirus Detection by RT-PCR Order code: 81602 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.25 mL plasma or CSF. Notes: Specimen source is required. Other acceptable: 1.0 mL CSF in a sterile container, frozen. Unacceptable: Nonfrozen samples, samples exposed to repeated freeze/thaw cycles, nonsterile or leaking containers, heparinized samples, and hemolyzed samples. Transport temp: Frozen Method: Reverse Transcription/Polymerase Chain Reaction Unit code: 813602 CPT Code(s): 87498 Ref range: By report Reported: 1-2 days Eosinophil Count, Nasal Smear Order code: 2315 Preferred specimen: 2 air-dried nasal smears Transport temp: Room temperature Method: Microscopic Examination Unit code: 201360 CPT Code(s): 89190 Ref range: By report Reported: 1-2 days Eosinophil Count-Absolute Order code: 2125 Preferred specimen: One 3-4 mL lavender top tube (EDTA). Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Room temperature Method: Automated Hematology Analyzer S1 0 Unit code: 201340 CPT Code(s): 85048 Ref range: 0-450/cumm Reported: Within 24 hours Eosinophilia Panel by FISH Order code: 80778 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL bone marrow or 2.0 mL whole blood Notes: Aids in diagnosis and classification of hematopoietic neoplasms presenting with prominent eosinophilia. Does not detect rearrangements associated with chronic myelogenous leukemia. Probes included: PDGFR-alpha, PDGFR-beta, FGFR1, CBFB. Please submit a Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) studies. Complete the form and submit with the test request form and specimen. Other acceptable: 10.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807780 CPT Code(s): 88271 (x4), 88275 (x4), 88291 Ref range: By report Reported: Varies Eosinophils, Urine Order code: 2530 Preferred specimen: 10 mL urine aliquot from a well-mixed random collection. Minimum specimen: 5 mL urine aliquot Unacceptable: Frozen samples or urine collected in preservative. Transport temp: Refrigerated Method: Wrights Stain/Microscopy Unit code: 250490 CPT Code(s): 89050 Ref range: None Seen Reported: Within 24 hours Test List 10-194 BBPL Directory of Services Epidermal Growth Factor Receptor (EGFR) by FISH Order code: 35957 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block (0.2 cm³ piece of tissue) or 4 slides (4 micron thickness) from formalin-fixed paraffin block. Unacceptable: Paraffin-embedded tissue that has been decalcified. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 535957 CPT Code(s): 88367 (x2) Ref range: By report Reported: 3-4 days Epidermal Growth Factor Receptor (EGFR) Mutation Analysis by PCR Order code: 35958 Preferred specimen: Formalin-fixed, paraffin-embedded (FFPE) tissue block containing greater than 25% tumor or five 7-micron thick sections in labeled container, and one H&E reference slide. Notes: Testing includes pathologist's interpretation. Other acceptable: Five precut, unstained slides from paraffin block in 7-micron thick sections and one H&E reference slide. Unacceptable: Tumor block containing insufficient tumor tissue. Transport temp: Room temperature Method: Real-Time Polymerase Chain Reaction Unit code: 535958 CPT Code(s): 81235, 88387, G0452 Ref range: By report Reported: Within 7 days Epstein-Barr Virus Antibody to Early Antigen Order code: 5354 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Grossly hemolyzed, lipemic, icteric, or contaminated specimens. Transport temp: Refrigerated S1 0 Method: Enzyme-linked Immunosorbant Assay Unit code: 353054 CPT Code(s): 86663 Ref range: Negative: < 0.91 Equivoval: 0.91-1.09 Positive: >1.09 Reported: 1-3 days Epstein-Barr Virus Antibody to Nuclear Antigen Order code: 5353 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Grossly hemolyzed, lipemic, icteric, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbant Assay Unit code: 353053 CPT Code(s): 86664 Ref range: Negative: < 0.91 Equivoval: 0.91-1.09 Positive: >1.09 Reported: 1-3 days Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG Order code: 5350 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Grossly hemolyzed, lipemic, icteric, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbant Assay Unit code: 353050 CPT Code(s): 86665 Ref range: Negative: < 0.91 Equivoval: 0.91-1.09 Positive: >1.09 Reported: 1-3 days 10-195 Test List BBPL Directory of Services Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG & IgM Order code: 5352 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Grossly hemolyzed, lipemic, icteric, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbant Assay Unit code: 353052 CPT Code(s): 86665 (x2) Ref range: Negative: < 0.91 Equivoval: 0.91-1.09 Positive: >1.09 Reported: 1-3 days Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM Order code: 5351 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Grossly hemolyzed, lipemic, icteric, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbant Assay Unit code: 353051 CPT Code(s): 86665 Ref range: Negative: < 0.91 Equivoval: 0.91-1.09 Positive: >1.09 Reported: 1-3 days Epstein-Barr Virus Comprehensive Profile Order code: 5345 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: Test includes: Viral Capsid Antigen, IgG Viral Capsid, Antigen, IgM Early Antigen Antibody Nuclear Antigen Antibody S1 0 Unacceptable: Grossly hemolyzed, lipemic, icteric, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbent Assay Unit code: 353045 CPT Code(s): 86663, 86664, 86665 (x2) Ref range: Negative: < 0.91 Equivoval: 0.91-1.09 Positive: >1.09 Reported: 1-3 days Epstein-Barr Virus, Qualitative PCR Order code: 38170 Preferred specimen: 1.0 mL serum, red top tube or SST, or plasma, lavender (EDTA) top tube. Remove serum or plasma from cells, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Indicate source on test request form. Minimum specimen: 0.25 mL serum, plasma, or CSF. Other acceptable: 1.0 mL CSF in sterile container, frozen. Unacceptable: Whole blood, heparinzed plasma, or bone marrow. Transport temp: Frozen Method: Polmerase Chain Reaction Unit code: 538170 CPT Code(s): 87798 Ref range: By report Reported: 1-7 days Equagesic See: Meprobamate Equanil See: Meprobamate Test List 10-196 BBPL Directory of Services ERA/PRA Receptor Assay, Paraffin Block Order code: 35210 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block. Tumor tissue is to be placed in 10% neutral buffered formalin as soon as possible, no later than 1 hour after removal from patient. Fixative duration: Minimum 6 hours, not to exceed 72 hours. Time from tissue acquisition to fixation and fixation duration should be recorded on test request form. Surgical pathology report should be included with specimen. For multiple samples, submit a separate test request form with each sample. Minimum specimen: 1 block with tumor Notes: Test includes: Estrogen Receptor Progesterone Receptor Pathologist review for presence of malignant cells. Unacceptable: Specimens fixed in any other fixative than 10% neutral buffered formalin, decalcified specimens, cytology samples fixed in alcohol, biopsies fixed for less than 6 hours or greater than 72 hours, samples where fixation was delayed for more than 1 hour. Paraffin block with no tumor tissue remaining. Transport temp: Room temperature Method: Image Analysis Unit code: 535210 CPT Code(s): 88361 (x2) Ref range: By report Reported: 3-7 days Erythrocyte Porphyrin (EP), Whole Blood Order code: 81387 Preferred specimen: 1.0 mL whole blood, royal blue (Na EDTA) or lavender (EDTA) top tube. Protect from light within 1 hour of collection and during 2 completely in aluminum foil or transfer whole blood to a plastic amber transport tube. storage and shipping. Wrap the tube Minimum specimen: 0.5 mL whole blood Notes: Use royal blue (Na EDTA) tube when also testing for lead. 2 Unacceptable: Specimens not collected in EDTA. Clotted specimens. Specimens not protected from light will be reported with disclaimer. Transport temp: Refrigerated Method: Extraction/Fluorometry Unit code: 813875 CPT Code(s): 84202 Ref range: 0-35 µg/dL Reported: 1-4 days S1 0 Erythropoietin Order code: 1184 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.4 mL serum or plasma Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Unacceptable: EDTA plasma or hemolyzed specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111084 CPT Code(s): 82668 Ref range: 4-20 mIU/mL Reported: 1-4 days Eskalith See: Lithium Estradiol, Serum Order code: 1284 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.3 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111085 CPT Code(s): 82670 Ref range: Female: Follicular Phase: 20-144 pg/mL Mid-Cycle Peak: 64-357 pg/mL Luteal Phase: 56-214 pg/mL Postmenopausal: 0-32 pg/mL Male: 0-40 pg/mL Reported: Within 24 hours 10-197 Test List BBPL Directory of Services Estriol, Serum Order code: 81425 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.6 mL serum Notes: Patient gestational age required. Avoid repeated freeze/thaw cycles. Unacceptable: Plasma Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 814025 CPT Code(s): 82677 Ref range: Based on gestational age: 25 weeks: 1.9 - 6.7 ng/mL 26 weeks: 2.0 - 7.3 ng/mL 27-29 weeks: 2.1 - 9.1 ng/mL 30-31 weeks: 2.4 - 10.6 ng/mL 32-37 weeks: 2.6 - 16.7 ng/mL Nonpregnant Female: Less than 0.08 ng/mL Male: Less than 0.16 ng/mL Reported: 1-2 days Estrogen & Progesterone Receptor Assay See: ERA/PRA Receptor Assay Estrogens, Fractionated by Tandem Mass Spectrometry Order code: 82410 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Notes: Recommended test for evaluating endogenous estrogen status in postmenopausal women, men, or children. Test Includes: Estradiol Estrone Estrogens Total Calculation Other acceptable: 0.5 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated S1 0 Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 814101 CPT Code(s): 82671 Ref range: By report Reported: 1-4 days Estrogens, Total Order code: 81421 Preferred specimen: 2.8 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 2.2 mL serum or plasma Notes: Patient must avoid having radioisotope scan prior to collection of specimen. Other acceptable: 2.8 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Gross hemolysis or lipemia, recent isotopic scan, icteric specimen. Transport temp: Refrigerated Method: Radioimmunoassay (RIA) Unit code: 814201 CPT Code(s): 82672 Ref range: By report Reported: 2-5 days Estrone, by Tandem Mass Spectrometry Order code: 83445 Preferred specimen: 0.5 mL serum, SST. Minimum specimen: 0.3 mL serum or plasma Notes: Remove serum or plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Other acceptable: 0.5 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 814301 CPT Code(s): 82679 Ref range: By report Reported: 1-4 days Test List 10-198 BBPL Directory of Services Ethanol, Blood, Qualitative Legal CRL COC Order code: 80163 Preferred specimen: 4.0 mL whole blood, gray (sodium fluoride/potassium oxalate) or lavender (EDTA) top tube. Do not prepare venipuncture site with alcohol. Submit original tube unopened, secured with tamper evident seal, with CRL chain of custody. Minimum specimen: 2.0 mL whole blood or serum Notes: CRL chain of custody form must be completed and submitted with specimen. Other acceptable: 4.0 mL serum, red top tube. Do not collect in SST. Submit original tube unopened, secured with tamper evident seal, with CRL chain of custody. Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) Unit code: 801603 CPT Code(s): 82055 Reported: 1-5 days Ethanol, Serum or Plasma Order code: 1215 Preferred specimen: 2.0 mL serum, red top tube. Remove serum from cells immediately after collection and transfer to a tightly-capped plastic transport tube to minimize alcohol loss. Do not collect in gel-barrier. Minimum specimen: 0.5 mL serum or plasma Notes: For medical purposes only. Other acceptable: 2.0 mL plasma, gray (sodium fluoride/potassium oxalate) or lavender (EDTA) top tube. Remove plasma from cells immediately after collection and transfer to a tightly-capped plastic transport tube. Sodium fluoride/potassium oxalate whole blood may be transported in the original container. Do not freeze whole blood. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Quantitative Gas Chromatography/Enzymatic Unit code: 801600 CPT Code(s): 82055 Ref range: Normal Range: Not established Therapeutic Range: (Therapy for methanol toxicity): 100-200 mg/dL Toxic Level: Greater than 250 mg/dL Toxic concentrations may cause inebriation, CNS depression, respiratory depression, mental and motor impairment and liver damage. In children, ethanol ingestion may cause hypoglycemia. Reported: 1-2 days S1 0 Ethanol, Urine Order code: 81438 Preferred specimen: 5.0 mL random urine in a plastic urine container. Minimum specimen: 1.6 mL urine Notes: A positive urine alcohol is only indicative of recent use and cannot be used to determine impairment. This test should be restricted to monitoring patients in drug treatment programs where any alcohol use is prohibited. Transport temp: Refrigerated Method: Enzymatic; gas chromatography (GC) quantitation (if positive by initial test) Unit code: 814380 CPT Code(s): 82055 Ref range: Negative (cutoff = 0.020%) Reported: 1-2 days Ethosuximide Order code: 86180 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Enzyme Immunoassay Unit code: 842500 CPT Code(s): 80168 Ref range: Therapeutic range: 40-100 µg/mL Toxic: Greater than 150 µg/mL The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Toxic concentrations may cause dizziness, drowsiness and anorexia. The incidence of adverse reactions is low; however, life-threatening agranulocytosis and fatal pancytopenia have been reported. Reported: 1-5 days 10-199 Test List BBPL Directory of Services Ethotoin Order code: 82450 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Gas Chromatography Unit code: 814350 CPT Code(s): 80299 Ref range: Dose-Related Range: 5-50 µg/mL Dose (Adult): 1-3 g/d Toxic: > 55 µg/mL Reported: 1-5 days Ethyl Glucuronide, Urine-Screen with Reflex to Confirmation Order code: 81439 Preferred specimen: 4.0 mL random urine with no additives or preservatives. Transport in a plastic transport tube or urine container. Minimum specimen: 1.0 mL urine Notes: Initial test to identify recent ethanol exposure (within 1 - 4 days after ingestion). Ethyl glucuronide is a direct metabolite of ethanol and can be detected up to 80 hours in urine after ethanol ingestion. The cutoff for positive by immunoassay is set at 500 ng/mL. A positive result will be confirmed by liquid chromatography tandem mass spectrometry (LC-MS/MS). Transport temp: Refrigerated Method: Qualitative Enzyme Immunoassay/Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 814397 CPT Code(s): 80101 Ref range: By report Reported: 1-4 days Ethylene Glycol Order code: 82455 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Enzymatic Assay Unit code: 814400 CPT Code(s): 82693 Ref range: No therapeutic range - Limit of detection 5 mg/dL Potentially toxic: > 20 mg/dL Reported: 1-4 days Etrafon See: Perphenazine Everolimus Order code: 84460 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 0.25 mL whole blood Notes: Pre-dose (trough) levels should be drawn. Unacceptable: Serum or plasma. Specimens left at room temperature for longer than 24 hours. Clotted specimens. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 814460 CPT Code(s): 80299 Ref range: Kidney transplant (in combinaion with Cyclosporine): 3-8 ng/mL Liver Transplant (in combination with Tacrolimus): 3-8 ng/mL Toxic Value: Greater than 15 ug/mL Reported: Within 24 hours Test List 10-200 S1 0 BBPL Directory of Services Eye Culture See: Culture, Eye Ezogabine and Metabolite Order code: 81447 Preferred specimen: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL plasma Notes: Trough levels are most reproducible. Transport temp: Frozen Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 814470 Ref range: By report Reported: 5-7 days Factor II, Activity (Prothrombin) Order code: 82480 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Separate samples must be submitted when multiple tests are ordered. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 808900 CPT Code(s): 85210 Ref range: 1-4 days: 26-70% 5-29 days: 33-93% 30-89 days: 34-102% 90-179 days: 45-105% 180-364 days: 60-116% 1-5 years: 71-116% 6 years: 67-107% 7-9 years: 78-125% 10-11 years: 78-120% 12-13 years: 72-123% 14-15 years: 75-135% 16-17 years: 77-130% 18 years and older: 86-150% S1 0 Reported: 1-4 days Factor II, Mutation See: Prothrombin Gene Mutation 10-201 Test List BBPL Directory of Services Factor IX Activity with Reflex to Bethesda Quantitative, Factor IX Order code: 80851 Preferred specimen: 6.0 mL platelet-poor plasma, three 3.5 mL light blue (3.2% sodium citrate) top tubes. Remove plasma from cells, transfer 3.0 mL plasma aliquots into 2 separate transport tubes and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: Two 2.0 mL aliquots of platelet-poor plasma. Notes: For hemophiliacs: Note dose, date, and time of last factor IX concentrate infusion on test request form. If Factor IX activity is 20% or less, then Bethesda Quantitative, Factor IX will be added at an additional charge. Unacceptable: Serum. Non-frozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 808951 CPT Code(s): 85250 Ref range: Factor IX, Activity: 1-4 days: 15-91% 5-29 days: 15-91% 30-89 days: 21-81% 90-179 days: 21-113% 180-364 days: 36-136% 1-5 years: 47-104% 6 years: 63-89% 7-9 years: 70-133% 10-11 years: 72-149% 12-13 years: 73-152% 14-15 years: 80-161% 16-17 years: 86-176% 18 years and older: 78-184% Bethesda Quantitative, Factor IX: 0.4 BU or less Reported: 1-4 days Factor IX, Activity Order code: 82490 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Order to diagnose factor IX deficiency (hemophilia B) and monitor factor IX replacement therapy. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. S1 0 Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 808950 CPT Code(s): 85250 Ref range: 1-4 days: 15-91% 5-29 days: 15-91% 30-89 days: 21-81% 90-179 days: 21-113% 180-364 days: 36-136% 1-5 years: 47-104% 6 years: 63-89% 7-9 years: 70-133% 10-11 years: 72-149% 12-13 years: 73-152% 14-15 years: 80-161% 16-17 years: 86-176% 18 years and older: 78-184% Reported: 1-4 days Factor V Leiden Mutation (G1691A) Order code: 36481 Preferred specimen: 5.0 mL whole blood collected in lavender (EDTA), light blue (sodium citrate) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Notes: Separate samples should be submitted when multiple tests are ordered. Other acceptable: Liquid Based Pap Media Unacceptable: Heparin anticoagulant, severely hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 536481 CPT Code(s): 81241 Ref range: By report Reported: 1-5 days Test List 10-202 BBPL Directory of Services Factor V, Activity Order code: 82510 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Separate samples must be submitted when multiple tests are ordered. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 809000 CPT Code(s): 85220 Ref range: 1-4 days: 36-108% 5-29 days: 45-145% 30-89 days: 62-134% 90-179 days: 48-132% 180-364 days: 55-127% 1-5 years: 79-127% 6 years: 63-116% 7-9 years: 69-132% 10-11 years: 66-136% 12-13 years: 66-135% 14-15 years: 61-129% 16-17 years: 65-131% 18 years and older: 62-140% Reported: 1-4 days Factor VII, Activity Order code: 82520 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Separate samples must be submitted when multiple tests are ordered. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 809050 CPT Code(s): 85230 S1 0 Ref range: 1-4 days: 28-104% 5-29 days: 35-143% 30-89 days: 42-138% 90-179 days: 39-143% 180-364 days: 47-127% 1-5 years: 55-116% 6 years: 52-120% 7-9 years: 67-145% 10-11 years: 71-163% 12-13 years: 78-160% 14-15 years: 74-180% 16-17 years: 63-163% 18 years and older: 80-181% Reported: 1-4 days Factor VIII Activity Flex to Bethesda Quantitative Order code: 82540 Preferred specimen: Two 3.0 mL aliquots of platelet-poor plasma, light blue (sodium citrate) top tubes. Remove plasma from cells, aliquot into 2 separate transport tubes and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: Two 2.0 mL aliquots of platelet-poor plasma Notes: For hemophiliacs: note dose, date, and time of last factor VIII concentrate infusion. If Factor VIII activity is 20% or less, then Bethesda Quantitative, Factor VIII will be added. Additional charges apply. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 809602 CPT Code(s): 85240 Ref range: Factor VIII, Activity: 0-6 years: 56-191% 7-9 years: 76-199% 10-11 years: 80-209% 12-13 years: 72-198% 14-15 years: 69-237% 16-17 years: 63-221% 18 years and older: 56-191% Bethesda Quantitative, Factor VIII: 0.5 BU or less Reported: 1-4 days 10-203 Test List BBPL Directory of Services Factor VIII Quantitation, Antigen Order code: 80909 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube. Blue top tube must be filled to completion to ensure proper blood to anticoagulant ratio. Mix the tube immediately by gentle inversion at least 6 times. Centrifuge immediately and remove the top two-thirds of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer plasma into a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Do not draw from an arm with a heparin lock or heparinized catheter. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Quantitates the amount of factor VIII protein; not a measure of von Willebrand factor antigen (previously called FVIII-related antigen). Unacceptable: Gross hemolysis, clotted whole blood, non-frozen specimens. Transport temp: Frozen Method: Enzyme-Linked Immunosorbent Assay (ELISA) Unit code: 809095 CPT Code(s): 83520 Ref range: 50-160 % Reported: 4-8 days Factor VIII, Activity Order code: 2815 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube filled to completion to ensure proper blood to anticoagulant ratio. Mix tube immediately by gentle inversion at least 6 times. Centrifuge immediately and remove only the top two-thirds of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma to a plastic transport tube and freeze immediately. Minimum specimen: 1.0 mL plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Serum, clotted or non-frozen specimens. Hemolyzed or lipemic specimens, or contamination with heparin. Transport temp: Frozen Method: Photo optic Unit code: 202815 CPT Code(s): 85240 Ref range: 50-150% Reported: 1-3 days Factor X, Activity Order code: 82560 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Separate samples must be submitted when multiple tests are ordered. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 809150 CPT Code(s): 85260 Ref range: 1-4 days: 12-68% 5-29 days: 19-79% 30-89 days: 31-87% 90-179 days: 35-107% 180-364 days: 38-118% 1-5 years: 58-116% 6 years: 55-101% 7-9 years: 74-130% 10-11 years: 70-134% 12-13 years: 69-133% 14-15 years: 63-146% 16-17 years: 74-146% 18 years and older: 81-157% Reported: 1-4 days Test List 10-204 S1 0 BBPL Directory of Services Factor XI, Activity Order code: 82565 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Separate samples must be submitted when multiple tests are ordered. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 809250 CPT Code(s): 85270 Ref range: 1-4 days: 10-66% 5-29 days: 23-87% 30-89 days: 27-79% 90-179 days: 41-97% 180-364 days: 38-134% 1-5 years: 56-150% 6 years: 52-120% 7-9 years: 70-138% 10-11 years: 66-137% 12-13 years: 68-138% 14-15 years: 57-129% 16-17 years: 65-159% 18 years and older: 56-153% Reported: 1-4 days Factor XII, Activity Order code: 82570 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Separate samples must be submitted when multiple tests are ordered. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 809300 CPT Code(s): 85280 S1 0 Ref range: 58-166% Reported: 1-4 days Factor XIII Activity Order code: 89355 Preferred specimen: 2.0 mL plasma, light blue (sodium citrate) top tube. Remove plasma from cells and place 1.0 mL into two separate transport tubes and FREEZE. Submit separate specimens when multiple tests are ordered. Minimum specimen: 2.0 mL plasma Transport temp: Frozen Method: Chrom Unit code: 809355 CPT Code(s): 85290 Ref range: 60-150% Reported: 3-8 days Factor XIII, Qualitative, with Reflex to Factor XIII 1:1 Mix Order code: 82575 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: This is a qualitative screening test; clot lysis only occurs in specimens with severe factor XIII deficiency (less than 1% of normal activity). Severe deficiency may be inherited or acquired (typically due to a factor XIII antibody). If clot lysis occurs in the initial testing, then Factor XIII 1:1 mix will be added where the test is repeated using a 1:1 mix of patient plasma and pooled normal plasma to distinguish between FXIII deficiency and a FXIII inhibitor. Additional charges apply. False-positive results (lysis) can be caused by heparin (therapy with unfractionated or low molecular weight heparin or contamination from a line), decreased or abnormal fibrinogen, increased fibrinolysis (inherited or acquired fibrinolytic disorders), fibrinolytic drugs, or other factors that affect clot structure or stability. Unacceptable: Serum. Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Qualitative Solubility Unit code: 809351 CPT Code(s): 85291 Ref range: Factor XIII, Qualitative: No lysis within 24 hours. Reported: 2-3 days 10-205 Test List BBPL Directory of Services Fat, Fecal See: Fecal Fat Qualitative Fecal Fat Quantitative Fatty Acids-Free Order code: 82580 Preferred specimen: 1.0 mL serum, gel-barrier tube. Collect on ice. Allow specimen to clot completely on ice. Remove serum from cells, transfer to a plastic transport tube and freeze immediately. Minimum specimen: 0.2 mL serum or plasma Notes: Overnight fasting specimen is preferred. Serum or plasma must be removed from cells and frozen ASAP, otherwise, lipase continues to break down triglycerides, giving rise to elevated levels of nonesterified (free) fatty acids. Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 1.0 mL plasma, lavender (EDTA), gray (sodium fluoride/potassium oxalate), or light blue (sodium citrate) top tube. Unacceptable: Non-frozen or heparinzed specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Spectrophotometry Unit code: 814500 CPT Code(s): 82725 Ref range: 0-5 months: less than or equal to 0.73 mmol/L 6 months-1 year: less than or equal to 0.99 mmol/L 2-17 years: less than or equal to 1.78 mmol/L 18 years or older: less than or equal to 0.78 mmol/L Reported: 1-4 days Febrile Antibodies Identification Panel Order code: 81454 Preferred specimen: 2.5 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Unacceptable: Contaminated or heat-inactivated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Agglutination/Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Immunoblot S1 0 Unit code: 814540 CPT Code(s): 86622, 86757 (x4), 86768 (x5) Ref range: Brucella Antibody (Total): <1:20 Negative Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgG: Less than 1:64: Negative - No significant level of Rickettsia rickettsii Antibody, IgG detected. 1:64 - 1:128: Low Positive - Presence of Rickettsia rickettsii Antibody, IgG detected, suggestive of current or past infection. 1:256 or greater: Positive - Presence of Rickettsia rickettsii Antibody, IgG suggestive of recent or current infection Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgM: Less than 1:64: Negative - No significant level of Rickettsia rickettsii Antibody, IgM detected. 1:64 or greater: Positive - Presence of Rickettsia rickettsii Antibody, IgM detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA: < 1:64 Negative - No significant level of Rickettsia typhi IgG antibody detected. 1:64 - 1:128 Equivocal - Questionable presence of Rickettsia typhi IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1:256 Positive - Presence of IgG antibody to Rickettsia typhi detected, suggestive of current or past infection. Rickettsia typhi (Typhus Fever) Antibody, IgM by IFA: < 1:64 Negative - No significant level of Rickettsia typhi IgM antibody detected. 1:64 Positive - Presence of IgM antibody to Rickettsia typhi detected, suggestive of recent infection. Salmonella typhi and paratyphi Antibodies: Negative Reported: 2-5 days Fecal Fat, Qualitative Order code: 2135 Preferred specimen: 2 gm aliquot of random solid stool or 1.0 mL liquid stool. Collection container should be free of oil residue. Minimum specimen: 1 gm aliquot of solid stool or 0.5 mL liquid stool. Notes: Patient should not ingest mineral oil or castor oil within 72 hours of collection. Barium procedures should be avoided prior to collection. Unacceptable: Specimens submitted in transport media. Transport temp: Refrigerated. Sample should be frozen if lab will not receive within 24 hours of collection. Method: Microscopic examination/Sudan stain Unit code: 250950 CPT Code(s): 89125 Ref range: Normal Reported: Within 24 hours Test List 10-206 BBPL Directory of Services Fecal Fat, Quantitative Order code: 82600 Preferred specimen: 24-, 48- or 72-hour stool collection. Refrigerate during collection. Send to laboratory refrigerated immediately after collection is complete. Contact BBPL Client Services for stool collection container. Include time of collection on test request form and specimen container. Notes: The patient should be on a diet consisting of 50 to 150 g of fat per day for 3 days prior to collection. Non-absorbable fat substitutes, such as Olestra, should be avoided prior to collection. Unacceptable: Specimens containing barium or charcoal. Specimens in media or preservatives. Specimens collected in paint cans. Random collections. Transport temp: Refrigerated Method: Nuclear Magnetic Resonance Spectroscopy Unit code: 814550 CPT Code(s): 82710 Ref range: 0-5 years: 0.0-2.0 g/24h 6 years and older: 0.0-6.0 g/24h Reported: 2-3 days Fecal Leukocyte Stain (WBC) Order code: 2165 Preferred specimen: Stool placed in PVA transport media. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to PVA medium, adding up to the fill line on the PVA vial label. Mix vial well. Stool specimen preserved in PVA medium is stable for 7 days stored at room temperature. Minimum specimen: 0.5 mL liquid stool or 1 gm solid (pea-sized) stool. Other acceptable: Fresh stool specimen in a clean, plastic screw-cap container is acceptable only if the specimen will be received in the testing laboratory within 2 hours of collection. Transport refrigerated. Fresh stool specimen refrigerated is stable for 2 hours. Unacceptable: Stool specimens preserved in formalin or Cary Blair medium or on swabs, fresh stool specimens stored at room temperature or frozen, multiple specimens (more than one in 24 hours). Transport temp: Room temperature Method: Trichrome stain/Microscopic Exam Unit code: 401960 CPT Code(s): 89055 Reported: 1-3 days S1 0 Fecal pH Order code: 2470 Preferred specimen: 5 mL random liquid stool, with no preservative. Minimum specimen: 2 mL liquid stool. Notes: Barium procedures should be avoided prior to collection of the specimen. Unacceptable: Formed stool. Specimen greater than 24 hours, if not frozen. Transport temp: Refrigerated. Freeze specimen if will not be received in laboratory within 24 hours after collection. Method: pH Indicator Strip Unit code: 251050 CPT Code(s): 83986 Ref range: pH: 7.0-7.5 Reported: Within 24 hours Fecal Reducing Substance See: Reducing Substances, Fecal Fecal, Chloride See: Chloride, Fecal Fecal, Electrolytes See: Electrolytes, Fecal Fecal, Potassium See: Potassium, Fecal Fecal, Sodium See: Sodium, Fecal 10-207 Test List BBPL Directory of Services Feces, Culture See: Culture, Stool with Shiga Toxin 1 and 2 by EIA Felbamate (Felbatol) Order code: 81473 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin) or gray (sodium fluoride/potassium oxalate) top tube. Unacceptable: Avoid use of separator tubes or gels. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography Unit code: 814730 CPT Code(s): 80299 Ref range: Therapeutic Range: Not well established. Toxic Level: Greater than 200 µg/mL The proposed therapeutic range for seizure control is 30-60 µg/mL. Pharmacokinetics vary widely, particularly with co-medications, age and/or compromised renal function. Felbamate use is associated with an increased incidence of liver failure and aplastic anemia. Reported: 1-4 days Fentanyl, Serum or Plasma See: Drug Confirmation, Quantitation Fentanyl & Metabolite, Serum or Plasma Fentanyl, Urine CRL COC Order code: 81251 Preferred specimen: 60 mL random urine in a plastic urine drug screen bottle with tamper evident tape. CRL chain of custody documentation is required. Minimum specimen: 20 mL urine Transport temp: Room temperature Method: Immunoassay/Gas Chromatography-Mass Spectrometry (GC/MS) S1 0 Unit code: 812521 CPT Code(s): 83925 Reported: 1-5 days Ferritin Order code: 1290 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Severely hemolyzed specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111090 CPT Code(s): 82728 Ref range: Males: 22-322 ng/mL Females: 10-291 ng/mL Reported: Within 24 hours Fetal Fibronectin Order code: 1790 Preferred specimen: Obtain the specimen using the Dacron swab in the Adeza Biomedical Specimen Collection Kit. The specimen should be taken from the posterior fornix of the vagina or the ectocervical region of the external cervical os. Notes: Specimens that are not tested within 8 hours of collection must be stored refrigerated at 2-8 C and assayed within 3 days. Unacceptable: Specimens collected in or by any sample device other than the Adeza Biomedical Specimen Collection Kit. Transport temp: Refrigerated Method: Solid Phase Enzyme Immunoassay Unit code: 120000 CPT Code(s): 82731 Ref range: By report Reported: Within 8 hours Test List 10-208 BBPL Directory of Services Fetal Lung Maturity Order code: 81474 Preferred specimen: 3.0 mL amniotic fluid submitted in sterile screw cap tube. Do not centrifuge. Protect from light. Minimum specimen: 2.0 mL amniotic fluid Notes: Lamellar Body Count (test 82316) is ran in conjunction with this test. Unacceptable: Specimens not protected from light. Transport temp: Frozen Unit code: 814745 CPT Code(s): 83663 Ref range: By report Reported: Within 24 hours Fetal Maternal Hemorrhage, Blood Order code: 83710 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.0 mL whole blood Notes: Specimen should arrive in laboratory within 24 hours. Unacceptable: Frozen or clotted specimens. Transport temp: Room temperature Method: Modified Kleihauer Unit code: 823000 CPT Code(s): 85460 Ref range: % Fetal Cells: 0.00 mLs Fetal Blood: 0.0 Reported: Within 24 hours FFN See: Fetal Fibronectin S1 0 Fibrinogen Order code: 82630 Preferred specimen: 1.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL plasma Unacceptable: Serum, EDTA plasma, nonfrozen, clotted or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Electromagnetic Mechanical Clot Detection Unit code: 814900 CPT Code(s): 85384 Ref range: 150-430 mg/dL Reported: Within 24 hours FibroSure See: Liver Fibrosis, Chronic Viral Hepatitis (Echosens FibroMeter) 10-209 Test List BBPL Directory of Services Fine Needle Aspiration (FNA) Specimen Collection See: Cytology, Fine Needle Aspiration (FNA) Cytology, Thyroid, Fine Needle Aspiration (FNA) Preferred specimen: FNA biopsies are helpful in: 1. Early tumor detection 2. Diagnosing tumor metastasis 3. Tumor staging 4. Post-therapeutic monitoring (recurrence) BBPL provides FNA collection kits that are available through Client Services or online using the BBPL Electronic Supply Order Form. Specimen: Aspirated cellular material from lesions/masses of all body sites submitted for evaluation and detection of malignant diseases. Collection: 1. Prepare several fixed slides and at least one non-fixed (air-dried) slide. Immediately after the needle is removed from the patient, remove the needle from the tip of the syringe, pull up 10 cc of air, and replace the needle on the syringe tip. This must be performed quickly, so that the material does not begin to dry or clot. The sample will be located within the needle and needle hub. With the needle facing away from the physician and patient, touch the needle tip to the glass slide, with the bevel edge down. Expel the sample onto one or more slides using the air from the syringe. Usually one small drop of specimen is adequate for each slide. If abundant material is obtained, it is often useful to split the sample onto several slides. Place the needle and syringe aside and immediately (1 to 3 seconds) take a spare glass slide and smear the drop of material. This is the preferred smearing technique for submission of specimens to the laboratory. Immediately place several smears in plastic slide holder with 95% alcohol. Send at least one air dried, non-fixed slide. An additional smearing method that is often used is to place two slides parallel to each other (with the sample between them) and rapidly pull the slides apart without exerting pressure between the slides. It is important not to use the "pop" technique or drag a cover slip across the slide as taught by hematology laboratories for blood films. These techniques cannot be used to smear the FNA sample because they will either drag the cellular clusters off the slide or create thick areas which cannot be interpreted. 2. Send Remaining Fluid. The remaining fluid should be submitted in a cytology container with equal amount of cytology fixative. After the direct smears have been prepared, remove the needle from the syringe.Use the syringe to draw up the cytology fixative fluid and then expel the remaining specimen into the cytology container. Place the lid on tightly for shipping to the laboratory. Notes: The frosted end of the microscopic slides and collection containers must be labeled with two (2) person specific identifiers and exact specimen site (e.g., left breast or right breast). Submit specimen with a completed Cytology request form that includes clinical history. Transport temp: Room temperature Fiorinal S1 0 See: Butalbital First Trimester Screening See: Maternal Serum Screen, First Trimester Flecainide Order code: 82660 Preferred specimen: 2.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Remove serum or plasma from cells within 6 hours of collection. Other acceptable: 2.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 815050 CPT Code(s): 80299 Ref range: Therapeutic Range: 0.20-1.00 µg/mL Toxic: > 1.50 µg/mL Reported: 1-5 days FLM See: Fetal Lung Maturity Test List 10-210 BBPL Directory of Services FLT3 Mutation Detection by PCR Order code: 81571 Preferred specimen: 5.0 mL whole blood or 3.0 mL bone marrow in a lavender (EDTA), yellow (solution A or B), or green (sodium or lithium heparin) top tube. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 4.0 mL whole blood or 1.0 mL bone marrow Unacceptable: Serum or plasma. Frozen or clotted whole blood or bone marrow. Severely hemolyzed specimens. Transport temp: Refrigerated Method: Qualitative Polymerase Chain Reaction/Capillary Electrophoresis Unit code: 815071 CPT Code(s): 81245, 81479 Ref range: By report Reported: 3-8 days Flu Screen A & B See: Influenza Antigen Screen A & B Fluid Cell Count & Differential See: Cell Count & Differential, Body Fluid Fluid, Crystals See: Crystals, Body Fluid Flunitrazepam & Metabolites, Serum or Plasma-Screen with Reflex to Confirmation Order code: 81508 Preferred specimen: 4.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells ASAP. Minimum specimen: 1.4 mL serum or plasma Notes: It is recommended that sample be submitted with chain of custody, but it is not required. If screen is positive, then confirmation will be added. Additional charges apply. Other acceptable: 4.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP. S1 0 Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Qualitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 815085 CPT Code(s): 80101 Ref range: By report Reported: 3-9 days Flunitrazepam & Metabolites, Urine-Screen with Reflex to Confirmation Order code: 81586 Preferred specimen: 3.0 mL random urine. Minimum specimen: 1.4 mL urine Notes: It is recommended that sample be submitted with chain of custody, but it is not required. If screen is positive, then confirmation will be added. Additional charges apply. Transport temp: Refrigerated Method: High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 815086 CPT Code(s): 80101 Ref range: By report Reported: 3-9 days 10-211 Test List BBPL Directory of Services Fluoride Quantitative, Serum Order code: 82670 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 1.0 mL serum or plasma Notes: Separate serum or plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube Unacceptable: Separator tubes or plasma collected in gray (potassium oxalate/sodium fluoride) top tube. Transport temp: Refrigerated Method: Ion Chromatography Unit code: 815100 CPT Code(s): 82735 Ref range: By report Reported: 3-9 days Fluoxetine Order code: 82697 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin) or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography Unit code: 815250 CPT Code(s): 80299 Ref range: Fluoxetine (Dose-Related Range): 100-800 ng/mL Norfluoxetine (Dose-Related Range): 100-600 ng/mL Fluoxetine and Norfluxetine Toxic: Greater than 2000 ng/mL Reported: 1-6 days Fluphenazine Order code: 84950 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Measure at least two weeks after initiating treatment. Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 832600 CPT Code(s): 84022 Ref range: Therapeutic Range: 0.5-2.0 ng/mL Toxic: Not well established Reported: 1-5 days Folate, RBC Order code: 1390 Preferred specimen: 1 lavender (EDTA) top tube, FREEZE. Perform hematocrit before freezing, record value on test requisition, or submit a second whole blood EDTA tube at room temperature for hematocrit to be performed. Notes: Minimize exposure to light. Separate specimens must be submitted when multiple tests are ordered. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 111420 CPT Code(s): 82747 Ref range: 280-790 ng/mL Reported: Within 24 hours Test List 10-212 S1 0 BBPL Directory of Services Folate, Serum Order code: 1250 Preferred specimen: 1.0 mL serum, red top tube or SST . Remove serum from cells, transfer to a plastic amber transport tube and refrigerate. Freeze serum if specimen will not be received in laboratory within 48 hours of collection. Protect from light. Minimum specimen: 0.5 mL serum Unacceptable: Plasma or hemolyzed specimens. Methotrexate and Leucovorin interfere with testing because these drugs cross-react with folate binding proteins. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111360 CPT Code(s): 82746 Ref range: >5.0 ng/mL Reported: Within 24 hours Follicle Stimulating Hormone, FSH Order code: 1286 Preferred specimen: 1.0 mL serum, SST or red top tube. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111096 CPT Code(s): 83001 Ref range: Females: Follicular Phase: 2.5-10.2 mIU/mL Mid-Cycle Peak: 3.4-33.4 mIU/mL Luteal Phase: 1.5-9.1 mIU/mL Postmenopausal: 23.0-116.3 mIU/mL Pregnancy: <0.3 mIU/mL Male: 1.4-18.1 mIU/mL Reported: Within 24 hours Fractionated Alkaline Phosphatase S1 0 See: Alkaline Phosphatase Isoenzymes Fragile X (FMR1) with Reflex to Methylation Analysis Order code: 82735 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.5 mL whole blood Notes: Please submit Patient History for Molecular Genetics and test request form with specimen. If an intermediate to expanded allele (CGG repeats) is detected by PCR and Capillary Electrophoresis; methylation analysis will be added to determine the size of the expanded CGG repeat. Additional charges apply. Preferred test to diagnose fragile X syndrome in individuals with characteristic clinical symptoms or screen healthy individuals for carrier status with or without a positive family history. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Capillary Electrophoresis Unit code: 815375 CPT Code(s): 81243 Ref range: By report Reported: 4-14 days 10-213 Test List BBPL Directory of Services Francisella tularensis Antibodies, IgG & IgM Order code: 81531 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Unacceptable: Contaminated, heat-inactivated, or turbid specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 815381 CPT Code(s): 86668 (x2) Ref range: Francisella tularensis Antibody, IgG: 9 U/mL or less Negative - No significant level of IgG antibody to Francisella tularensis detected. 10-15 U/mL Equivocal - Questionable presence of IgG antibody to Francisella tularensis. Repeat testing in 10-14 days may be helpful. 16 U/mL or greater Positive - Presence of IgG antibody to Francisella tularensis detected, suggestive of current or past exposure/immunization. Francisella tularensis Antibody, IgM: 9 U/mL or less Negative - No significant level of IgM antibody to Francisella tularensis detected. 10-15 U/mL Equivocal - Questionable presence of IgM antibody to Francisella tularensis. Repeat testing in 10-14 days may be helpful. 16 U/mL or greater Positive - Presence of IgM antibody to Francisella tularensis detected, suggestive of current or recent exposure/immunization. Reported: 1-6 days Free Calcium See: Calcium, Ionized Free Kappa & Lambda Light Chains, Quantitative, Urine Order code: 82671 Preferred specimen: Two 4.0 mL urine aliquots from a well-mixed 24-hour urine collection. Keep refrigerated at all times. Record the total volume and hours of collection on both the urine container and the test request form. Minimum specimen: 3.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Other acceptable: Random urine specimens and urine supernate. Unacceptable: Frozen specimens. Transport temp: Refrigerated S1 0 Method: Immunofixation Electrophoresis/Nephelometry Unit code: 821671 CPT Code(s): 83883 (x2), 84156, 86335 Ref range: Total Protein: 10-140 mg/d Albumin: Detected Alpha-1 Globulins: None detected Alpha-2 Globulins: None detected Beta Globulins: None detected Gamma Globulins: None detected Free Urinary Kappa Light Chains: 0.14-2.42 mg/dL Free Urinary Kappa Excretion/Day: By report Free Urinary Lambda Light Chain: 0.02-0.67 mg/dL Free Urinary Lambda Excretion/Day: By report Free Urinary Kappa/Lambda Ratio: 2.04-10.37 (ratio) IFE Interpretation: By report Reported: 1-5 days Free Phenytoin See: Phenytoin, Free Free T3 See: T3 Free Free T4, Serum See: Thyroxine (T4) ,Free Test List 10-214 BBPL Directory of Services Fructosamine Order code: 82750 Preferred specimen: 1.0 mL serum, SST. Minimum specimen: 0.5 mL serum or plasma Notes: Remove serum or plasma from cells within 45 minutes of collection. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Gross hemolysis or lipemia. Transport temp: Refrigerated Method: Colorimetric Unit code: 815400 CPT Code(s): 82985 Ref range: 0-285 umol/L Reported: 1-3 days Fructose, Semen Order code: 85360 Preferred specimen: 1.0 mL semen. Freeze semen immediately in a plastic transport container. Minimum specimen: 0.3 mL semen Transport temp: CRITICAL FROZEN Method: Spectrophotometry Unit code: 837100 CPT Code(s): 82757 Ref range: 91-520 mg/dL Reported: 1-8 days FSH, Serum See: Follicle Stimulating Hormone FTA-ABS, Fluorescent Treponema pallidum Antibody, Serum with Reflex to TP-PA S1 0 Order code: 82760 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Unacceptable: CSF, plasma, or other body fluids. Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Particle Agglutination Unit code: 815550 CPT Code(s): 86780 Ref range: Nonreactive The Fluorescent Treponema Antibody (FTA) is recommended for follow-up of reactive nontreponemal tests for syphilis, and as a single test in patients suspected of late syphilis. The FTA may be used to resolve discrepancies between laboratory results and clinical impressions. FTA tests for syphilis may be falsely positive in some cases of systemic lupus erythematosus, pregnancy, and leprosy. The FTA test is not recommended for cerebrospinal fluid specimens. For CSF specimens, the VDRL-CSF test is recommended. Inconclusive results will be repeated by TP-PA to aid the physician in diagnosis. Inconclusive final reports indicate the initial specimen submitted has been tested twice and cannot be interpreted as either reactive or nonreactive. If it is the second specimen submitted on a patient and the report is again inconclusive, it is impossible to state definitively that the patient does or does not have syphilitic infection. Reflex will only happen when the FTA is found to be inconclusive. Additional charges apply. Reported: 1-4 days Fungal Antibodies by CF, Serum Order code: 81567 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.35 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent." Unacceptable: Severely lipemic or contaminated specimens. Transport temp: Refrigerated Method: Complement Fixation Unit code: 815670 CPT Code(s): 86606, 86612, 86635, 86698 (x2) Ref range: Aspergillus Antibody by CF: < 1:8 Blastomyces Antibody by CF: <1:8 Coccidioides Antibody by CF: <1:2 Histoplasma Yeast Antibody by CF: <1:8 Histoplasma Mycelia Antibody by CF: <1:8 Reported: 2-4 days 10-215 Test List BBPL Directory of Services Fungal Culture Order code: 3620 Preferred specimen: Sputum: Collect sputum in a tightly sealed sterile 50 mL centrifuge tube or in other sterile screw-cap container. Refrigerate. Spinal Fluid: Submit 2.0 mL CSF in a sterile screw-cap tube. Refrigerate. Swab: Swab affected area with a sterile culture swab and transport at room temperature. Tissue: Submit tissue specimen in sterile screw-cap container. Add only enough sterile saline to moisten tissue. Refrigerate. Peritoneal and Pleural Fluids: Submit fluid in yellow (SPS) top vacutainer tube or in a tightly sealed sterile 50 mL centrifuge tube. Refrigerate. Notes: Indicate source of specimen on test request form. Unacceptable: Dried swab or leaking container. Transport temp: Refer to individual specimen type. Method: Fungal Culture Techniques Unit code: 401500 CPT Code(s): 87102 Ref range: Culture negative for fungus Reported: Within 4 weeks Fungal Culture and Stain Order code: 3600 Preferred specimen: Sputum: Collect sputum in a tightly sealed sterile 50 mL centrifuge tube or in other sterile screw-cap container. Refrigerate. Spinal Fluid: Submit 2.0 mL CSF in a sterile screw-cap tube. Refrigerate. Swab: Swab affected area with a sterile culture swab and transport at room temperature. Tissue: Submit tissue specimen in sterile screw-cap container. Add only enough sterile saline to moisten tissue. Refrigerate. Peritoneal and Pleural Fluids: Submit fluid in yellow (SPS) top vacutainer tube or in a tightly sealed sterile 50 mL centrifuge tube. Refrigerate. Notes: Indicate source of specimen on test request form. Unacceptable: Dried swab or leaking container. Transport temp: Refer to individual specimen type. Method: Fungal Culture Techniques/Calcofluor White Stain or India Ink Unit code: 401600 S1 0 CPT Code(s): 87102, 87206 Ref range: Culture negative for fungus Reported: Culture: Within 4 weeks Stain: Within 24 hours Fungal Culture and Stain, Blood Order code: 3602 Preferred specimen: 7.0 mL whole blood or bone marrow in yellow (SPS) top vacutainer tube or Lysis-Centrifugation tube. Minimum specimen: 1.0 mL whole blood or 0.5 mL bone marrow. Unacceptable: Specimens in tube other than SPS or Lysis-Centrifugation. Refrigerated or frozen specimens. Transport temp: Room temperature Method: Fungal Culture Techniques/Calcofluor White Stain Unit code: 401620 CPT Code(s): 87103, 87206 Ref range: Culture negative for fungus Reported: Within 4 weeks Final: Negative at 4 weeks. Positive cultures are reported as soon as detected. Fungal Culture and Stain, Skin, Hair or Nails Order code: 3601 Preferred specimen: Submit skin scrapings, hair or nail specimens in sterile screw-cap container. Do not tape specimens to a slide or put in a moist environment (saline). There must be enough specimen to be readily visible. Notes: Indicate source of specimen on test request form. Unacceptable: Specimens in formalin or saline. Transport temp: Room temperature Method: Fungal Culture Techniques/KOH Unit code: 401610 CPT Code(s): 87101, 87220 Ref range: Culture negative for fungus Reported: Within 4 weeks Test List 10-216 BBPL Directory of Services Fungal Culture, Blood Order code: 3622 Preferred specimen: 7.0 mL whole blood or bone marrow in yellow (SPS) top vacutainer tube or Lysis-Centrifugation tube. Minimum specimen: 1.0 mL whole bood or 0.5 mL bone marrow. Unacceptable: Specimen in tube other than SPS or Lysis-Centrifugation. Refrigerated or frozen specimens. Transport temp: Room temperature Method: Fungal Culture Techniques Unit code: 401520 CPT Code(s): 87103 Ref range: Culture negative for fungus Reported: Within 4 weeks Final: Negative at 4 weeks. Positive cultures are reported as soon as detected. Fungal Culture, Skin, Hair or Nails Order code: 3621 Preferred specimen: Submit skin scrapings, hair or nail specimens in sterile screw-cap container. Do not tape specimens to a slide or put in a moist environment (saline). There must be enough specimen to be readily visible. Notes: Indicate source of specimen on test request form. Unacceptable: Specimens in formalin or saline. Transport temp: Room temperature Method: Fungal Culture Techniques Unit code: 401510 CPT Code(s): 87101 Ref range: Culture negative for fungus Reported: Within 4 weeks Fungal Screen I Order code: 82770 Preferred specimen: 4.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.8 mL serum Notes: Test includes: Aspergillus Antibody by Iummunodiffusion Blastomyces Antibodies by CF & ID Candida Antibody by Immunodiffusion Coccidioides Antibodies, IgG & IgM Histoplasma Antibody by ID S1 0 Unacceptable: Plasma or body fluid specimens. Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Complement Fixation/Immunodiffusion/Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 815601 CPT Code(s): 86606, 86612, 86628, 86635 (x2), 86698 Ref range: See individual tests. Reported: 2-5 days Fungal Screen II Order code: 82790 Preferred specimen: 4.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: Test includes: Aspergillus Antibodies by Immunodiffusion Blastomyces Antibodies by CF & ID Candida Antibody by Immunodiffusion Coccidioides Antibodies, IgG & IgM Histoplasma Antibodies by CF Histoplasma Antibody by ID Unacceptable: Plasma or body fluid specimens. Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Complement Fixation/Immunodiffusion/Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 815701 CPT Code(s): 86606, 86612 (x2), 86628, 86635 (x2), 86698 (x3) Ref range: See individual tests. Reported: 2-5 days 10-217 Test List BBPL Directory of Services Fungal Smear Only Order code: 3640 Preferred specimen: Sputum: Collect sputum in a tightly sealed sterile 50 mL centrifuge tube or in other sterile screw-cap container. Spinal Fluid: Submit 1 mL CSF in a sterile screw-cap tube. Tissue: Submit tissue specimen in sterile screw-cap container. Add only enough sterile saline to moisten tissue. Swab: Swab affected area with a sterile culture swab. Notes: Indicate source of specimen on test request form. Transport temp: Room temperature Method: Calcofluor White Fluorescent Stain or India Ink Unit code: 401700 CPT Code(s): 87206 Ref range: Negative for fungal elements Reported: Within 24 hours Fungal Stain KOH, Genital Order code: 2433 Preferred specimen: Use a sterile culture transport swab to collect genital specimen. The specimen must be tested within two hours after collection or placed into Diamond's media to preserve for transport to laboratory. Diamond's media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Other acceptable: Sterile culture swab in a small amount of sterile saline (less than 2 mL). Unacceptable: Swab in culturette or dry swab. Transport temp: Room temperature Method: KOH/Microscopic Examination Unit code: 401933 CPT Code(s): 87210 Ref range: Negative for yeast Reported: Within 48 hours Fungal Stain KOH, Skin, Hair, Nails Order code: 2275 Preferred specimen: Submit skin scrapings, hair or nail specimens in sterile screw-cap container. Do not tape specimens to a slide or put in a moist environment (saline). There must be enough specimen to be readily visible. Indicate source on test request form. Unacceptable: Specimens in formalin or saline. Specimens on glass slides or tape. Specimens too small to see visually. Transport temp: Room temperature Method: KOH/Microscopic examination Unit code: 401930 CPT Code(s): 87220 Ref range: Negative for fungal elements Reported: Within 48 hours G-6-PD See: Glucose-6-Phosphate Dehydrogenase Gabapentin Order code: 82725 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Room temperature Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 827265 CPT Code(s): 80171 Ref range: 4.0-16.0 µg/mL Reported: 3-5 days Gabitril See: Tiagabine GAD Antibody See: Glutamic Acid Decarboxylase Antibody Test List 10-218 S1 0 BBPL Directory of Services GAD65 Antibody See: Glutamic Acid Decarboxylase Antibody Galactose-1-Phosphate, Uridyltransferase Order code: 82807 Preferred specimen: 7.0 mL whole blood, lavender (EDTA) or green (sodium or lithium heparin) top tube. Collect on ice. Minimum specimen: 3.0 mL whole blood Notes: A Patient History For Galactosemia form is required to perform galactosemia DNA testing. Complete the form and submit with the test request form and specimen. Unacceptable: Hemolyzed specimens. Frozen and room temperature specimens. Transport temp: Refrigerated Method: Enzymatic Unit code: 815850 CPT Code(s): 82775 Ref range: 14.7-25.4 U/g Hb Reported: 2-4 days Galactosemia (GALT) Enzyme Activity & 9 Mutations Order code: 81549 Preferred specimen: 10.0 mL whole blood, lavender (EDTA) top tubes. Transport whole blood tubes to laboratory refrigerated. Do not freeze. Minimum specimen: 3.0 mL whole blood Notes: A Patient History For Galactosemia form is required to perform galactosemia DNA testing. Complete the form and submit with the test request form and specimen. Other acceptable: 10.0 mL whole blood, green (sodium heparin) top tubes. Unacceptable: Frozen or room temperature specimens. Transport temp: Refrigerated Method: Enzymatic/Polymerase Chain Reaction/Single Nucleotide Extensions Unit code: 815849 CPT Code(s): 81401, 82775 Ref range: By report Reported: 7-10 days S1 0 Galectin-3 Order code: 81605 Preferred specimen: 0.8 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.4 mL serum or plasma Other acceptable: 0.8 mL plasma, lavender (EDTA) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Plasma other than EDTA, hemolyzed specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 816005 CPT Code(s): 82777 Ref range: By report Reported: 2-5 days GALOP Antibody Order code: 81610 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Unacceptable: Do not freeze. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay (ELISA) Unit code: 816010 Ref range: Titers <10,000 Reported: 7-10 days 10-219 Test List BBPL Directory of Services Gamma-Glutamyltransferase, GGT Order code: 1305 Preferred specimen: 1.0 mL serum, red top tube or ge-barrier tube. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Kinetic Unit code: 101820 CPT Code(s): 82977 Ref range: 0-65 U/L Reported: Within 24 hours Ganglioside (Asialo-GM1, GM1, GM2, GD1a, GD1b, GQ1b) Antibodies Order code: 81652 Preferred specimen: 0.3 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Unacceptable: Room temperature specimens. Plasma, CSF, or other body fluids. Contaminated, heat-inactivated, hemolyzed , severely icteric, or lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 816052 CPT Code(s): 83516 Ref range: Asialo-GM1 Antibodies, IgG/IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong Positive GM1 Antibodies, IgG/IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong Positive GM2 Antibodies, IgG/IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong Positive S1 0 GD1a Antibodies, IgG/IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong Positive GD1b Antibodies, IgG/IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong Positive GQ1b Antibodies, IgG/IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong Positive Reported: 1-4 days Ganglioside (GM1) Antibodies, IgG/IgM Order code: 82816 Preferred specimen: 0.3 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, CSF, and other body fluids. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens. Room temerature specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 816050 CPT Code(s): 83516 (x2) Ref range: GM1 Antibody IgG: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong positive GM1 Antibody, IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong positive Reported: 1-4 days Test List 10-220 BBPL Directory of Services Garamycin See: Gentamicin, Trough Gentamicin, Peak Gentamicin, Random Gardnerella vaginalis DNA Probe Order code: 36015 Preferred specimen: Collect vaginal fluid specimen using BD Affirm VPIII Ambient Temperature Transport System. Specimens must be collected and transported in the manufacturer's test specific swab kits. BD Affirm VPIII Transport System is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Unacceptable: Swabs submitted in media other than BD Affirm VPIII Ambient Temperature Transport System. Transport temp: Room temperature Method: Nucleic Acid Probe Unit code: 536015 CPT Code(s): 87510 Ref range: Negative Reported: 1-3 days Gastric Parietal Cell Antibody, IgG See: Parietal Cell Antibody, IgG Gastrin Order code: 1216 Preferred specimen: 1.0 mL serum, red top tube or gel-barrier tube. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.3 mL serum Notes: Twelve hour fasting recommended. Unacceptable: Plasma or non-frozen serum. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 111100 S1 0 CPT Code(s): 82941 Ref range: Up to 100 pg/mL Reported: 1-3 days 10-221 Test List BBPL Directory of Services Gastrointestinal Pathogen Panel Order code: 38070 Preferred specimen: Stool specimen placed into Cary Blair transport media. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to Cary Blair medium, adding up to the fill line on the Cary Blair vial label. Mix vial well. Cary Blair media is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Minimum specimen: 0.2 mL liquid stool Notes: Test includes: Bacteria: Campylobacter Clostridium difficile (Toxin A/B) Plesiomonas shigelloides Salmonella Yersinia enterocolitica Vibrio Vibrio cholerae Enteroaggregative E. Coli (EAEC) Enteropathogenic E. Coli (EPEC) Enterotoxigenic E. Coli (ETEC) lt/st Shiga-like toxin-producing E. Coli (STEC) stx1/stx2 E. Coli O157 Shigella/Enteroinvasive E. Coli (EIEC) Parasites: Cryptosporidium Cyclospora cayetanensis Entamoeba histolytica Giardia lamblia Viruses: Adenovirus F40/41 Astrovirus Norovirus GI/GII Rotavirus A Sapovirus Unacceptable: Specimens in inappropriate transport media or frozen specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 538070 CPT Code(s): 87493, 87798 (x3) Ref range: Not Detected Reported: Within 24 hours S1 0 GC (Neisseria gonorrhoeae) See: Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel by SDA Neisseria gonorrhoeae DNA by SDA Neisseria gonorrhoeae Antibodies, Total Culture, Neisseria gonorrhoeae (GC) Only GC/CT DNA See: Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel by SDA Gengraf See: Cyclosporine A Genital Culture See: Culture, Genital Test List 10-222 BBPL Directory of Services Genital Panel I Order code: 36006 Preferred specimen: Two separate specimen types are required. Refer to individual tests for detailed specimen requirements. Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel: APTIMA® vaginal swab, APTIMA® unisex swab (for endocervical and male urethral specimens), APTIMA® urine tube, or PreservCyt (ThinPrep) liquid Pap specimen. Directions for specimen collection and handling are provided on the APTIMA® collection kits. APTIMA® kits are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Candida, Gardnerella, and Trichomonas DNA Probes: Collect vaginal fluid specimen using BD Affirm VPIII Ambient Temperature Transport System. Specimens must be collected and transported in the manufacturer's test specific swab kits. BD Affirm VPIII Transport System is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Notes: Test profile includes: Chlamydia trachomatis DNA Neisseria gonorrhoeae DNA Candida species DNA Probe Gardnerella vaginalis DNA Probe Trichomonas vaginalis DNA Transport temp: Room temperature Method: Chlamydia trachomatis & Neisseria gonorrhoeae: Nucleic Acid Amplification Test (NAAT) Candida, Gardnerella, and Trichomonas: Nucleic Acid Probe Unit code: 536006 CPT Code(s): 87480, 87491, 87510, 87591, 87661 Ref range: Negative Reported: 2-5 days Genital Panel II Order code: 36050 Preferred specimen: APTIMA® vaginal swab, APTIMA® unisex swab (for endocervical and male urethral specimens), or PreservCyt (ThinPrep) liquid Pap specimens. Directions for specimen collection and handling are provided on the APTIMA® collection kits. APTIMA® kits are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Specimen source is required. Record source on test request form. ® Minimum specimen: 1 APTIMA swab or tube, 1.0 mL ThinPrep or SurePath liquid Pap specimen. Notes: Test panel includes: Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel Trichomonas vaginalis DNA Probe Herpes Simplex Viruses DNA Unacceptable: Large white swab in unisex kit is for preparatory cleaning of the endocervix and is unacceptable for testing. Specimens in any transport media other than indicated above. Specimen in swab transport media without a swab. Transport temp: Refrigerated S1 0 Method: Chlamydia trachomatis & Neisseria gonorrhoeae: Nucleic Acid Amplification Test (NAAT) Trichomonas: Nucleic Acid Probe Herpes Simple Viruses: Polymerase Chain Reaction (PCR) Unit code: 536050 Ref range: Negative Reported: 2-7 days Genital Panel III Order code: 36005 Preferred specimen: Collect vaginal fluid specimen using BD Affirm VPIII Ambient Temperature Transport System. Specimens must be collected and transported in the manufacturer's test specific swab kits. BD Affirm VPIII Transport System is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Unacceptable: Swabs submitted in media other than BD Affirm VPIII Ambient Temperature Transport System. Transport temp: Room temperature Method: Nucleic Acid Probe Unit code: 536005 CPT Code(s): 87480, 87510, 87660 Ref range: Candida species DNA Probe Gardnerella vaginalis DNA Probe Trichomonas vaginalis DNA Probe Negative Negative Negative Reported: 1-3 days 10-223 Test List BBPL Directory of Services Genital Panel IV Order code: 36055 Preferred specimen: APTIMA® vaginal swab, APTIMA® unisex swab (for endocervical and male urethral specimens), APTIMA® urine tube, or PreservCyt (ThinPrep) liquid Pap specimens. Directions for specimen collection and handling are provided on the APTIMA® collection kits. APTIMA® kits are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. ® Minimum specimen: 1 APTIMA swab or tube, 1.0 mL ThinPrep or SurePath liquid Pap specimens, 2.0 mL neat urine. Notes: Test panel includes: Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel Trichomonas vaginalis DNA Probe Other acceptable: SurePath liquid Pap specimen. 5.0 mL neat (unpreserved) first catch urine in sterile urine cup. Unacceptable: Large white swab in unisex kit is for preparatory cleaning of the endocervix and is unacceptable for testing. Specimens in any transport media other than indicated above. Specimen in swab transport media without a swab. Transport temp: Room temperature Method: Chlamydia trachomatis & Neisseria gonorrhoeae: Nucleic Acid Amplification Test (NAAT) Trichomonas: Nucleic Acid Probe Unit code: 536055 CPT Code(s): 87491, 87591, 87798 Ref range: Negative Reported: 2-5 days Genpril See: Ibuprofen Gentamicin, Peak Order code: 1152 Preferred specimen: 1.0 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Draw peak samples 30 minutes after 30 minute IV infusion or within 15 minutes after a 60-minute IV infusion. For IM injections, draw 60 minutes post IM injection. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 110040 CPT Code(s): 80170 Ref range: Therapeutic: 5.0-10.0 µg/mL Toxic: >12.0 µg/mL Reported: Within 24 hours Gentamicin, Random Order code: 1153 Preferred specimen: 1.0 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 110030 CPT Code(s): 80170 Ref range: Therapeutic: Trough: <2.0 µg/mL Peak: 5.0-10.0 µg/mL Toxic: Trough: >2.5 µg/mL Peak: >12.0 µg/mL Reported: Within 24 hours Test List 10-224 S1 0 BBPL Directory of Services Gentamicin, Trough Order code: 1151 Preferred specimen: 1.0 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Draw trough sample immediately prior to or within 1 hour of next dose. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 110035 CPT Code(s): 80170 Ref range: Therapeutic: <2.0 µg/mL Toxic: >2.5 µg/mL Reported: Within 24 hours German Measles See: Rubella Antibody, IgG Rubella Antibody, IgM GGT, Serum See: Gamma-Glutamyltransferase GGTP See: Gamma-Glutamyltransferase, GGT Giardia Antigen, EIA, Stool S1 0 Order code: 3465 Preferred specimen: Stool placed in 10% formalin or Cary Blair transport media. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to formalin or Cary Blair medium, adding up to the fill line on the transport vial label. Mix vial well. Stool specimen preserved in formalin or Cary Blair medium is stable for 7 days stored at room temperature. Minimum specimen: 0.5 mL liquid stool or 1 g solid (pea-sized) stool. Other acceptable: Fresh stool specimen in a clean, plastic screw-cap container is acceptable only if the specimen will be received in the testing laboratory within 2 hours of collection. Transport refrigerated. Unacceptable: Stool specimens preserved in PVA medium or multiple specimens (more than one in 24 hours). Transport temp: Room temperature Method: Enzyme Immunoassay Unit code: 402010 CPT Code(s): 87329 Ref range: Negative Reported: 1-3 days Giardia lamblia Antibodies Panel Order code: 86252 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 1 hour of collection, transfer to a plastic transport tube and freeze immediately. Minimum specimen: 0.5 mL serum Transport temp: Frozen Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 816252 CPT Code(s): 86674 (x3) Ref range: By report Reported: 3-10 days 10-225 Test List BBPL Directory of Services Gliadin Antibodies, IgG & IgA Order code: 3655 Preferred specimen: 1.0 mL serum, SST. Minimum specimen: 0.5 mL serum Unacceptable: Plasma. Hemolyzed, icteric, lipemic or bacterially contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 360755 CPT Code(s): 83516 (x2) Ref range: Gliadin Antibody, IgG: Negative: <20 EU/mL Indeterminate: 20-25 EU/mL Positive: >25 EU/mL Gliadin Antibody, IgA: Negative: <20 EU/mL Indeterminate: 20-25 EU/mL Positive: >25 EU/mL Reported: 1-5 days Gliadin Antibody, IgA Order code: 3651 Preferred specimen: 0.5 mL serum, SST. Minimum specimen: 0.25 mL serum Unacceptable: Plasma. Hemolyzed, icteric, lipemic or bacterially contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 360751 CPT Code(s): 83516 Ref range: Negative: <20 EU/mL Indeterminate: 20-25 EU/mL Positive: >25 EU/mL Reported: 1-5 days Gliadin Antibody, IgG Order code: 3650 Preferred specimen: 0.5 mL serum, SST. Minimum specimen: 0.25 mL serum Unacceptable: Plasma. Hemolyzed, icteric, lipemic or bacterially contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 360750 CPT Code(s): 83516 Ref range: Negative: <20 EU/mL Indeterminate: 20-25 EU/mL Positive: >25 EU/mL Reported: 1-5 days Glomerular Basement Membrane Antibody, IgG Order code: 80730 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Transport temp: Refrigerated Method: Semi-Quantitative Multiplex Bead Assay/Qualitative Indirect Fluorescent Antibody Unit code: 816400 CPT Code(s): 83516, 86255 Ref range: Glomerular Basement Membrane Antibody, IgG by Multiplex Bead Assay: Negative: 19 AU/mL or less Equivocal: 20-25 AU/mL Positive: 26 AU/mL or greater Glomerular Basement Membrane Antibody, IgG (IFA): Negative Reported: 1-5 days Test List 10-226 S1 0 BBPL Directory of Services Glucagon Order code: 82850 Preferred specimen: Collect 3.0 mL whole blood using protease inhibitor tube available through BBPL Client Services or online using BBPL Electronic Supply Order Form. A winged collection set must be used. NOT RECOMMENDED: Filling collection tubes directly through a needle/tube-holder assembly increases the risk of chemical reflux back into the vein of the patient. WARNING: Collection tubes are NOT STERILE. Follow the collection instructions provided with the protease inhibitor tube. Mix collection tube thoroughly. Centrifuge and remove plasma from cells within 1 hour of collection. Transfer 1.0 mL plasma to a plastic transport tube and freeze immediately. Do not submit the collection tube for testing. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL plasma Unacceptable: Grossly hemolyzed specimens. Transport temp: Frozen Method: Radioimmunoassay Unit code: 816450 CPT Code(s): 82943 Ref range: Adult: Less than or equal to 65 ng/L Reported: 3-11 days Glucose Gestational Screen, 1 Hour (50 gm Glucose Challenge) Order code: 1140 Preferred specimen: 1.0 mL serum, SST. Collect specimen 1 hour after 50 gm glucose load. Remove serum from cells ASAP. Label specimen with time drawn. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Hexokinase Unit code: 101515 CPT Code(s): 82950 Ref range: 70-139 mg/dL Reported: Within 24 hours Glucose Gestational Screen, Fasting and 1 Hour (50 gm Glucose Challenge) S1 0 Order code: 15060 Preferred specimen: 1.0 mL serum, SST, for each timed specimen (fasting and 1 hour). First specimen collected as fasting. Second specimen collected 1 hour after 50 gm glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102180 CPT Code(s): 82947, 82950 Ref range: By report Reported: Within 24 hours Glucose Panel, Fasting and 2 Hour (75 gm Glucose Challenge) Order code: 15061 Preferred specimen: 1.0 mL serum, SST, for each timed specimen (fasting and 2 hour). First specimen collected as fasting. Second specimen collected 2 hours after 75-gm glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 101561 CPT Code(s): 82947, 82950 Ref range: By report Reported: Within 24 hours 10-227 Test List BBPL Directory of Services Glucose Panel, Fasting and Postprandial 1 Hour Order code: 1362 Preferred specimen: 1.0 mL serum, SST, for each timed specimen (fasting and 1 hour). First specimen collected as fasting. Second specimen collected 1 hour following a meal. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Transport temp: Refrigerated Method: Hexokinase Unit code: 101555 CPT Code(s): 82947, 82950 Ref range: Fasting 70-99 mg/dL Reported: Within 24 hours Glucose Panel, Fasting and Postprandial 2 Hour Order code: 1363 Preferred specimen: 1.0 mL serum, SST, for each timed specimen (fasting and 2 hour). First specimen collected as fasting. Second specimen collected 2 hours following a meal. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Transport temp: Refrigerated Method: Hexokinase Unit code: 101560 CPT Code(s): 82947, 82950 Ref range: Fasting 70-99 mg/dL Reported: Within 24 hours Glucose Tolerance, 2 Hour (75 gm Glucose) 4 Specimens Order code: 15065 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1/2 hour, 1 hour and 2 hour). Collect a fasting specimen, then administer 75 gm glucose load. Collect subsequent specimens 1/2, 1, and 2 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated S1 0 Method: Hexokinase Unit code: 102100 CPT Code(s): 82951, 82952 Ref range: By report Reported: Within 24 hours Glucose Tolerance, 3 Hour (75 gm Glucose) 5 Specimens Order code: 15070 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1/2 hour, 1 hour, 2 hour, and 3 hour). Collect a fasting specimen, then administer 75 gm glucose load. Collect subsequent specimens 1/2, 1, 2, and 3 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102120 CPT Code(s): 82951, 82952 (x2) Ref range: By report Reported: Within 24 hours Glucose Tolerance, 4 Hour (75 gm Glucose) 6 Specimens Order code: 15075 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1/2 hour, 1 hour, 2 hour, 3 hour, and 4 hour). Collect a fasting specimen, then administer 75 gm glucose load. Collect subsequent specimens 1/2, 1, 2, 3, and 4 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102140 CPT Code(s): 82951, 82952 (x3) Ref range: By report Reported: Within 24 hours Test List 10-228 BBPL Directory of Services Glucose Tolerance, 5 Hour (75 gm Glucose) 7 Specimens Order code: 15080 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1/2 hour, 1 hour, 2 hour, 3 hour, 4 hour, and 5 hour). Collect a fasting specimen, then administer 75 gm glucose load. Collect subsequent specimens 1/2, 1, 2, 3, 4, and 5 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102150 CPT Code(s): 82951, 82952 (x4) Ref range: By report Reported: Within 24 hours Glucose Tolerance, 6 Hour (75 gm Glucose) 8 Specimens Order code: 15082 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1/2 hour, 1 hour, 2 hour, 3 hour, 4 hour, 5 hour, and 6 hour). Collect a fasting specimen, then administer 75 gm glucose load. Collect subsequent specimens 1/2, 1, 2, 3, 4, 5, and 6 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102160 CPT Code(s): 82951, 82952 (x5) Ref range: By report Reported: Within 24 hours Glucose Tolerance-Gestational, 2 Hour (100 gm Glucose) 3 Specimens S1 0 Order code: 15074 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1 hour and 2 hour). Collect a fasting specimen, then administer 100 gm glucose load. Collect subsequent specimens 1 and 2 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102173 CPT Code(s): 82951 Ref range: By report Reported: Within 24 hours Glucose Tolerance-Gestational, 3 Hour (100 gm Glucose) 4 Specimens Order code: 15072 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1 hour, 2 hour, and 3 hour). Collect a fasting specimen, then administer 100 gm glucose load. Collect subsequent specimens 1, 2, and 3 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102170 CPT Code(s): 82951, 82952 Ref range: By report Reported: Within 24 hours 10-229 Test List BBPL Directory of Services Glucose Tolerance-Gestational, 3 Hour (100 gm Glucose) 5 Specimens Order code: 15073 Preferred specimen: 1.0 mL serum, SST for each timed specimen (fasting, 1/2 hour, 1 hour, 2 hour, and 3 hour). Collect a fasting specimen, then administer 100 gm glucose load. Collect subsequent specimens 1/2, 1, 2, and 3 hours post glucose load. Remove serum from cells ASAP. Label each specimen with time drawn. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Patient should be fasting (no consumption of food or beverage other than water) for 8-12 hours prior to testing and avoid smoking or excessive exercise during this time. Transport temp: Refrigerated Method: Hexokinase Unit code: 102171 CPT Code(s): 82951, 82952 (x2) Ref range: By report Reported: Within 24 hours Glucose, CSF Order code: 1360 Preferred specimen: 1.0 mL CSF in a plastic transport tube. Centrifuge and separate to remove cellular material. Minimum specimen: 1.0 mL CSF Transport temp: Refrigerated Method: Hexokinase Unit code: 103080 CPT Code(s): 82945 Ref range: 45-75 mg/dL Reported: Within 24 hours Glucose, Fluid Order code: 1354 Preferred specimen: 1.0 mL body fluid in a plastic transport tube. Minimum specimen: 0.5 mL fluid Notes: Indicate source on test request form. Transport temp: Refrigerated Method: Hexokinase S1 0 Unit code: 103100 CPT Code(s): 82945 Ref range: None established Reported: Within 24 hours Glucose, Post Glucola, 2 Hour Order code: 1356 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Hexokinase Unit code: 101530 CPT Code(s): 82950 Reported: Within 24 hours Glucose, Postprandial, 1 Hour Order code: 1358 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Hexokinase Unit code: 101510 CPT Code(s): 82950 Reported: Within 24 hours Test List 10-230 BBPL Directory of Services Glucose, Postprandial, 2 Hour Order code: 1357 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Hexokinase Unit code: 101520 CPT Code(s): 82947 Reported: Within 24 hours Glucose, Serum Order code: 1001 Preferred specimen: 1.0 mL serum, gel-barrier tube. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Hexokinase Unit code: 101500 CPT Code(s): 82947 Ref range: 70-99 mg/dL Reported: Within 24 hours Glucose, Urine, Quantitative Order code: 82855 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour collection. Refrigerate 24-hour specimen during collection period. Record total volume and hours of collection on both the urine container and test request form. TIME SENSITIVE: Freeze urine aliquot and send to the laboratory within 24 hours after completion of collection. Minimum specimen: 0.5 mL urine aliquot Other acceptable: Random specimens are acceptable but have no reference intervals. Unacceptable: Urine collected in preservatives. Transport temp: Frozen S1 0 Method: Enzymatic Unit code: 816600 CPT Code(s): 82945 Ref range: 24-hour urine: less than 500 mg/d Reported: Within 24 hours Glucose-6-Phosphate Dehydrogenase Order code: 82860 Preferred specimen: 3.0 mL whole blood, yellow (ACD Solution A) top tube. Minimum specimen: 1.5 mL whole blood Notes: Enzyme most stable in acid citrate dextrose (ACD). Do not freeze. Other acceptable: 3.0 mL whole blood, green (sodium or lithium heparin) or lavender (EDTA) top tube. Unacceptable: Hemoyzed specimens. Transport temp: Refrigerated Method: Enzymatic Unit code: 816500 CPT Code(s): 82955 Ref range: 9.9-16.6 U/g Hb Reported: 1-2 days Glutamic Acid Decarboxylase (GAD) Antibody Order code: 81665 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and refrigerate. If serum specimen will be stored for longer than 1 week, freeze the serum. Minimum specimen: 0.4 mL serum Unacceptable: Specimens other than serum; recently administered radioisotopes; lipemic or grossly hemolyzed serum. Transport temp: Refrigerated Method: Radioimmunoassay Unit code: 816605 CPT Code(s): 83519 Ref range: 0.0-1.5 units/mL Reported: 2-5 days 10-231 Test List BBPL Directory of Services Glycohemoglobin A1c with Estimated Average Glucose Order code: 1905 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) top tube. Specimen is stable at room temperature for 24 hours. Transport refrigerated if specimen will not be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL whole blood Transport temp: Refrigerated Method: High Performance Liquid Chromatography Unit code: 115500 CPT Code(s): 83036 Ref range: 4.0-5.6% Reported: 1-2 days Gold, Quantitative Order code: 82900 Preferred specimen: 1.0 mL serum, trace metal-free royal blue (no additive) top tube. Minimum specimen: 0.4 mL serum or plasma Notes: Remove serum or plasme from cells and transfer to a trace element-free transport tube. Refrigerated. Also acceptable at room temperature or frozen. Other acceptable: 1.0 mL plasma, trace metal-free royal blue (EDTA) top tube. Unacceptable: Separator tubes Transport temp: Refrigerated Method: Quantitative Graphite Furnace Atomic Absorption Spectroscopy Unit code: 816800 CPT Code(s): 80172 Ref range: By report Reported: 3-9 days Gram Stain Smear Order code: 3420 Preferred specimen: Two unfixed slides smeared with sample or specimen from culture swab. If accompanying a culture, two sterile swabs are recommended, one for the culture and one for the gram stain. Also acceptable, any amount of liquid specimen in a sterile screwcap container. Notes: Indicate source of specimen on test request form. S1 0 Unacceptable: Do not tape specimen to slide. Do not use coverslip or place another slide on top of the specimen slide. Transport temp: Room temperature Method: Gram Stain Unit code: 406000 CPT Code(s): 87205 Reported: Within 24 hours Granulocytic Antibodies See: Neutrophil Associated Antibodies Group A Strep Culture See: Culture, Beta Strep, Throat Group A Strep Rapid Antigen See: Streptococcus Group A Rapid Antigen with Reflex to Culture Group B Strep Culture See: Culture, Group B Screen Group B Strep Culture with Sensitivities See: Culture, Group B Streptococcus with Sensitivities Test List 10-232 BBPL Directory of Services Growth Hormone Order code: 83370 Preferred specimen: 0.8 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Notes: Patient should be fasting and have rested for at least 30 minutes prior to specimen collection. Unacceptable: Grossly hemolyzed or lipemic specimens, plasma specimens. Transport temp: Refrigerated Method: Immunochemiluminometric assay (ICMA) Unit code: 820650 CPT Code(s): 83003 Ref range: 0.0-10.0 ng/mL Reported: 1-3 days Guaiac See: Occult Blood, Stool Haemophilus influenza b Vaccine Response See: Haemophilus influenzae b Antibody, IgG Haemophilus influenzae b Antibody, IgG Order code: 82215 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine". "Pre" and 30-day "post" Haemophilus influenzae b vaccination specimens should be submitted together for testing. "Post" specimen should be drawn 30 days after immunization and must be received within 60 days of "pre" specimen. Minimum specimen: 0.15 mL serum Unacceptable: Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Quantitative Multiplex Bead Assay Unit code: 822105 CPT Code(s): 86317 S1 0 Ref range: < 1.0 µg/mL = Antibody concentration not protective. 1.0 µg/mL = Antibody to H. influenzae b detected. Suggestive of protection. Responder status is determined according to the ratio of post-vaccination concentration to pre-vaccination concentration of Haemophilus influenza b antibody, IgG as follows: 1. If the post-vaccination concentration is less than 3.0 µg/mL, the patient is considered to be a nonresponder. 2. If the post-vaccination concentration is greater than or equal to 3.0 µg/mL, a patient with a ratio of greater than or equal to 4 is a good responder, a ratio of 2-4 is a weak responder, and a ratio of less than 2 is considered a nonresponder. Reported: 1-2 days HairStat 5 Reflexive Panel Order code: 81704 Preferred specimen: Collect 100 mg of hair (a ponytail, approximately 200 strands, 1.5 inches long and the diameter of a #2 pencil). Select a clump of hair in the crown area of the head. Cut the donor's hair as close to the scalp as possible. Ensure that the hair is not synthetic or has not been bleached, dyed, or permanently waved within the past three months. If so, collect body hair. Hair from the beard, underarms, chest, arms, legs or pubic hair may be collected. Body hair from different sites may be combined to get a final volume. Body hair and scalp hair should not be combined during collection. A Hairstat kit must be used for specimen collection and is available through BBPL Client Services. Follow directions included in the Hair Collection kit for specimen collection and handling. Submissions require tamper evident seal to be placed on the specimen collection container. Unsealed containers will be rejected. Specific Chain of Custody form required for testing. Minimum specimen: 100 mg hair. Notes: Drug test includes: amphetamines, cocaines, opiates, PCP, and cannabinoids. If screen is positive, then confirmation will be added at no additional charge. A 1.5 inch specimen of head hair represents approximately three months of hair growth, and therefore, up to three months of collective history of drug exposure. Unacceptable: Dying, bleaching, perming, and straightening of hair may affect results. Transport temp: Room temperature Method: Qualitative Enzyme-Linked Immunosorbent Assay/Quantitative Gas Chromatography-Mass Spectrometry Unit code: 817040 CPT Code(s): 80101 (x5) Ref range: By report Reported: 3-6 days 10-233 Test List BBPL Directory of Services Haloperidol (Haldol) Order code: 82930 Preferred specimen: 4.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 1.6 mL serum or plasma Other acceptable: 4.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Separator tubes or gels Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 817100 CPT Code(s): 80173 Ref range: Therapeutic: 4-26 ng/mL Potentially toxic: >50 ng/mL Reported: 2-5 days Ham Test See: Acid Hemolysin (Ham Test) Haptoglobin Order code: 1248 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Fasting specimen is preferred. Minimum specimen: 1.0 mL serum Unacceptable: Hemolyzed or extremely lipemic specimens. Specimens other than serum. Transport temp: Refrigerated Method: Nephelometry Unit code: 112480 CPT Code(s): 83010 Ref range: 34-200 mg/dL Reported: 1-3 days S1 0 HBcAb See: Hepatitis B Core Antibody, Total HBeAb See: Hepatitis Be Virus Antibody HBeAg See: Hepatitis Be Virus Antigen HBsAb See: Hepatitis B Surface Antibody HBsAg See: Hepatitis B Surface Antigen hCG See: hCG, Beta Quantitative Tumor Marker hCG, Qualitative Urine Human Chorionic Gonadotropin, Qualitative, Pregnancy Serum Human Chorionic Gonadotropin, Quantitative, Females hCG, Beta Quantitative Tumor Marker See: Beta-hCG, Quantitative Tumor Marker Test List 10-234 BBPL Directory of Services hCG, Qualitative Urine Order code: 2215 Preferred specimen: 10 mL urine aliquot from a first morning voided specimen. Minimum specimen: 1 mL urine Unacceptable: Specimens collected with preservative (IPT). Transport temp: Refrigerated up to 48 hours, frozen if >48 hours. Method: Immunoassay Unit code: 250510 CPT Code(s): 81025 Ref range: Negative Reported: Within 24 hours HCV See: Hepatitis C Antibody Hepatitis C Antibody with Reflex to Hepatitis C RNA Quantitative PCR Hepatitis C RNA, Qualitative PCR Hepatitis C RNA, Quantitative PCR Hepatitis C RNA, Quantitative PCR with Reflex to Genotype Hepatitis C Virus Genotype HDL Cholesterol Order code: 1310 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: A twelve (12) hour fast is recommended. Transport temp: Refrigerated Method: Elimination/Catalase Unit code: 103120 CPT Code(s): 83718 Ref range: > or = 40 mg/dL Reported: Within 24 hours S1 0 HDV See: Hepatitis Delta Antibody Hepatitis Delta Antigen Heat Shock Protein 70 (68 kDa) Order code: 82740 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.1 mL serum. Unacceptable: Hemolyzed or lipemic specimens. Specimens with large clots present or bacterial growth. Specimens collected with anticoagulants or preservatives. Transport temp: Refrigerated Method: Western Blot Unit code: 822740 CPT Code(s): 84182 Ref range: Negative Reported: 2-8 days Heavy Metal Profile, Blood Order code: 82970 Preferred specimen: 7.0 mL whole blood, royal blue (K EDTA) or (Na EDTA) top tube, in the original collection tube at room temperature or 2 refrigerated is also acceptable. 2 Minimum specimen: 2.0 mL whole blood Notes: Test includes: Arsenic Lead Mercury Unacceptable: Heparin anticoagulant. Frozen specimens. Transport temp: Room temperature Method: Quantitative Atomic Absorption/Quantitative Inductively Coupled Plasma-Mass Spectrometry Unit code: 817451 CPT Code(s): 82175, 83655, 83825 Ref range: By report Reported: 1-3 days 10-235 Test List BBPL Directory of Services Heavy Metals Panel 3, Urine with Reflex to Arsenic Fractionated Order code: 82990 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random collection. Specimen must be collected in a plastic container and should be refrigerated during collection period. Submit urine in two trace element-free transport tubes. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 2.0 mL urine aliquot Notes: Test includes: Arsenic, Lead, Mercury. If total arsenic concentration is between 35-2000 µg/L, then Arsenic Fractionated will be added to determine the proportion of organic, inorganic, and methylated forms. Additional charges apply. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies) or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry/High Performance Liquid Chromatography Unit code: 817500 CPT Code(s): 82175, 83655, 83825 Ref range: By report Reported: 1-4 days Heavy Metals Panel 4, Urine with Reflex to Arsenic Fractionated Order code: 81750 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random collection. Specimen must be collected in a plastic container and should be refrigerated during collection period. Submit urine in two trace element-free transport tubes. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 2.0 mL urine aliquot Notes: Test includes: Arsenic, Lead, Mercury, Cadmium. If total arsenic concentration is between 35-2000 µg/L, Arsenic Fractionated will be added to determine the proportion of organic, inorganic, and methylated forms. Additional charges apply. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd.) containing contrast media (may occur with MRI studies) or acid preserved urine. Transport temp: Refrigerated S1 0 Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 817505 CPT Code(s): 82175, 82300, 83655, 83825 Ref range: By report Reported: 1-4 days Heinz Body Stain Order code: 7205 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.5 mL whole blood Transport temp: Room temperature Method: Microscopic examination Unit code: 702005 CPT Code(s): 85441 Ref range: By report Reported: 1-3 days Helicobacter pylori Antibodies, IgG, IgA, IgM Order code: 81728 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum Notes: Test Includes: Helicobacter pylori Antibody, IgA Helicobacter pylori Antibody, IgG Helicobacter pylori Antibody, IgM Unacceptable: Severely lipemic, icteric, contaminated, heat-inactivated, or hemolyzed specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Enzyme Immunoassay Unit code: 817628 CPT Code(s): 86677 (x3) Ref range: See individual tests. Reported: 1-5 days Test List 10-236 BBPL Directory of Services Helicobacter pylori Antibody, IgA Order code: 81724 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Hemolysis, lipemia, or gross bacterial contamination. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 817624 CPT Code(s): 86677 Ref range: Negative: <9.0 Units Equivocal: 9.0 - 11.0 Units Positive: >11.0 Units Reported: 1-3 days Helicobacter pylori Antibody, IgG Order code: 5380 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.5 mL serum Unacceptable: Grossly icteric and contaminated specimens. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbant Assay Unit code: 353080 CPT Code(s): 86677 Ref range: Negative: <0.9 Index Equivoval: 0.9-1.1 Index Positive: >1.1 Index Reported: 1-3 days Helicobacter pylori Antibody, IgM Order code: 81727 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum or plasma Unacceptable: Hemolysis, lipemia, or gross bacterial contamination. S1 0 Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 817627 CPT Code(s): 86677 Ref range: Negative: <9.0 Units Equivocal: 9.0 - 11.0 Units Positive: >11.0 Units Reported: 1-5 days Helicobacter pylori Antigen, Stool Order code: 81765 Preferred specimen: 2 g (thumbnail size portion) of stool or 2.0 mL liquid stool in sterile screw-cap container. Minimum specimen: 1 g stool or 1.0 mL liquid stool Transport temp: Frozen Method: Immunoassay Unit code: 817615 CPT Code(s): 87338 Ref range: Negative Reported: 3-5 days 10-237 Test List BBPL Directory of Services Helicobacter pylori Breath Test Order code: 81761 Preferred specimen: Order BreathTek UBT® Collection Kit through BBPL Client Services. Collect specimens according to the instructions in the kit. Patient Preparation: This test requires the patient to drink a solution (Pranactin-Citric) containing aspartame, citric acid, and mannitol. Caution should be taken when administering this test to phenylketonurics and patients with hypersensitivities to these ingredients. The patient should fast and abstain from smoking for 1 hour prior to test administration. The patient should not have taken antibiotics, proton pump inhibitors (e.g., Prilosec®, Prevacid®, Aciphex®, Nexium®), or bismuth preparations (e.g., Pepto-Bismol®) within the previous 14 days. When used to monitor treatment, the test should be performed four weeks after cessation of definitive therapy. Additional warnings and precautions are included with the BreathTek UBT kit. Please review these carefully. Pediatric specimens from persons 17 years or younger cannot be used with this collection kit. Specimen Collection: 1) Label breath collection bags with patient name, date and time of collection, and designate Pre (blue) or Post (pink). 2) Collect the baseline breath specimen: a) Remove cap from collection bag (blue). b) Have patient take a deep breath, pause momentarily then exhale into the mouthpiece of the bag filling it completely. c) Replace cap on the bag. 3) Prepare Pranactin®-Citric solution: a) Empty packet from test kit into the cup provided. b) Add drinking water up to the fill line (raised ridge). c) Replace lid; swirl for up to two minutes until completely dissolved. Solution should be clear. The solution is stable up to 60 minutes at room temperature. 4) Instruct patient to drink the solution without stopping using the straw provided. Advise the patient not to "rinse" the mouth with the solution before swallowing. 5) Set timer for 15 minutes. Start timer as soon as the patient has completed drinking. Patient should sit quietly without eating, drinking, or smoking. 6) Prepare the post specimen collection (pink) bag. At exactly 15 minutes, have the patient take a deep breath, pause momentarily and then exhale to fill the second sample collection bag (pink). Note: for a valid result, the post specimen must be collected within 13 to 18 minutes after administration of the Pranactin®-Citric Solution. Transport: Place both specimen bags (blue and pink) in a plastic specimen transport bag with test request form and send to the laboratory at room temperature. Do not refrigerate or freeze specimen collection bags. Unacceptable: Bags not fully inflated or only one of the two bags submitted. Refrigerated or frozen specimen bags. Breath collected in tubes. Post breath specimens collected earlier than 13 minutes or later than 18 minutes after patient drinks the testing solution. Pediatric specimens from persons 17 years or younger. Transport temp: CRITICAL ROOM TEMPERATURE Method: Qualitative Spectrophotometry Unit code: 817610 CPT Code(s): 83013 Ref range: Negative Reference intervals for pediatric patients have not been established. S1 0 Reported: 1-4 days Helicobacter pylori CLO Test, Gastric Order code: 3430 Preferred specimen: Place gastric biopsy into Rapid Urea medium immediately after obtaining specimen. Rapid Urea medium available through BBPL Client Services. Notes: Incubate specimen at 37°C and observe for the first hour for a pink color change. A pink color indicates a positive reaction. Send to the Microbiology Laboratory for additional observation. Transport temp: Room temperature Method: Rapid Urease Unit code: 402050 CPT Code(s): 87077 Ref range: Negative Screen Reported: Within 24 hours Hematocrit Order code: 2235 Preferred specimen: One 3-4 mL lavender top tube (EDTA). Refrigerate EDTA tube if specimen will not be received in laboratory within 24 hours of collection. Stability: Room temperature 24 hours, refrigerated 48 hours. Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Refrigerated Method: Automated Hematology Analyzer Unit code: 200300 CPT Code(s): 85014 Ref range: Adult Male: 37.0-53.0% Adult Female: 34.5-46.5% Reported: Within 24 hours Heme Profile See: CBC with Automated Differential Test List 10-238 BBPL Directory of Services Hemochromatosis (HFE) 3 Mutations Order code: 83005 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Transport temp: Refrigerated Method: Polymerase Chain Reaction/Fluorescence Monitoring Unit code: 817650 CPT Code(s): 81256 Ref range: C282Y Negative: The patient is negative for the HFE C282Y mutation. H63D Negative: The patient is negative for the HFE H63D mutation. S65C Negative: The patient is negative for the HFE S65C mutation. Reported: 2-7 days Hemoglobin A1c See: Glycohemoglobin A1c with Estimated Average Glucose Hemoglobin A2 and F Order code: 83030 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.0 mL EDTA whole blood Unacceptable: Ambient or frozen samples. Transport temp: Refrigerated Method: High Performance Liquid Chromatography Unit code: 817800 CPT Code(s): 83021 Ref range: By report Reported: 1-4 days Hemoglobin Evaluation Reflexive Cascade S1 0 Order code: 87752 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube. A Patient History for Hemoglobinopathy/Thalassemia Testing form along with test request form must be submitted with specimen. Patient history form, including information from a recent CBC, is required for interpretation. Minimum specimen: 2.0 mL whole blood Notes: Optimal test for the initial and confirmatory diagnosis of any suspected hemoglobinopathy. Do not use for the follow-up of an individual with a known diagnosis. The Hemoglobin Evaluation Reflexive Cascade begins with HPLC analysis. If an abnormal hemoglobin is detected or if the CBC data is suggestive of a hemoglobinopathy, appropriate testing will be performed at an additional charge. Depending on findings, one or more reflexive tests may be required in order to provide a clinical interpretation. Tests added may include electrophoresis, solubility testing, mutational analysis and/or sequencing. Quantitation of hemoglobin by HPLC or electrophoresis is most definitive in individuals one year of age and older. If quantitation of hemoglobin was performed before one year of age, repeat testing is recommended. Abnormal hemoglobin variants may require additional testing, which increases TAT up to 21 days. Unacceptable: Frozen or room temperature specimens. Transport temp: Refrigerated Method: High Performance Liquid Chromatography/Electrophoresis/RBC Solubility/Polymerase Chain Reaction/Fluorescence Resonance Energy Transfer/Sequencing Unit code: 817752 CPT Code(s): 83021 Ref range: By report Reported: Varies Hemoglobin Evaluation with Reflex to Electrophoresis and/or RBC Solubility Order code: 83020 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube. A Patient History for Hemoglobinopathy/Thalassemia Testing form along with test request form must be submitted with specimen. Minimum specimen: 0.2 mL EDTA whole blood Notes: Effective test for screening and follow-up of individuals with known hemoglobinopathies. The optimal test for the initial diagnosis of a suspected hemoglobinopathy is the Hemoglobin Evaluation Reflexive Cascade (order code 87752). If HPLC detects any abnormal peaks suggestive of a hemoglobin variant, then further testing (RBC Solubility, Acid or Alkaline Electrophoresis, Capillary Electrophoresis) will be performed at an additional charge. In infants age 1 year and older, quantitation of hemoglobin is recommended for definitive diagnosis. Unacceptable: Frozen or room temperature specimens. Transport temp: Refrigerated Method: High Performance Liquid Chromatography/Electrophoresis/RBC Solubility Unit code: 817750 CPT Code(s): 83021 Ref range: By report Reported: 1-7 days 10-239 Test List BBPL Directory of Services Hemoglobin, Plasma Order code: 83040 Preferred specimen: 2.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP. Delayed separation from cells will elevate plasma hemoglobin. Minimum specimen: 0.7 mL plasma Unacceptable: EDTA and citrated plasma. Transport temp: Refrigerated Method: Spectrophotometry Unit code: 817850 CPT Code(s): 83051 Ref range: 0.5-5.0 mg/dL Reported: 1-2 days Hemoglobin, Serum Order code: 81751 Preferred specimen: 2.0 mL serum, SST. Allow specimen to clot completely at room temperature. Remove serum from cells ASAP. Delayed separation from cells will elevate serum hemoglobin. Minimum specimen: 0.7 mL serum Transport temp: Refrigerated Method: Spectrophotometry Unit code: 817851 CPT Code(s): 84311 Ref range: 0.5-8.0 mg/dL Reported: 1-2 days Hemoglobin-Hemogram Order code: 2234 Preferred specimen: One 3-4 mL lavender (EDTA) top tube. Refrigerate EDTA tube if specimen will not be received in laboratory within 24 hours of collection. Stability: Room temperature 24 hours, refrigerated 48 hours. Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Refrigerated S1 0 Method: Automated Hematology Analyzer Unit code: 200295 CPT Code(s): 85018 Ref range: Hemoglobin Adult Male: 12.0-18.0 gm/dL Adult Female: 11.5-16.0 gm/dL Reported: Within 24 hours Hemoglobin/Hematocrit Order code: 2224 Preferred specimen: One 3-4 mL lavender (EDTA) top tube. Refrigerate EDTA tube if specimen will not be received in laboratory within 24 hours of collection. Stability: Room temperature 24 hours, refrigerated 48 hours. Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Refrigerated Method: Automated Hematology Analyzer Unit code: 200306 CPT Code(s): 85014, 85018 Ref range: Hemoglobin: Adult Male: 12.0-18.0 gm/dL Adult Female: 11.5-16.0 gm/dL Hematocrit: Adult Male: 37.0-53.0% Adult Female: 34.5-46.5% Reported: Within 24 hours Test List 10-240 BBPL Directory of Services Hemogram Order code: 2225 Preferred specimen: One 3-4 mL lavender (EDTA) top tube. Refrigerate EDTA tube if specimen will not be received in laboratory within 24 hours of collection. Stability: Room temperature 24 hours, refrigerated 48 hours. Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Notes: Test includes: WBC, RBC, Hgb, Hct, MCV, MCH, MCHC. RDW, and Platelet count. Other acceptable: If platelet clumping is a problem, submit both EDTA and sodium citrate (blue top) tubes. Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Refrigerated Method: Automated Hematology Analyzer Unit code: 200400 CPT Code(s): 85027 Ref range: Adult: WBC M/F 4.0-12.0 thou/cumm RBC Male 3.8-5.8 mil/cumm, Female 3.9-5.2 mil/cumm Hgb Male 12.0-18.0 gm/dL, Female 11.5-16.0 gm/dL Hct Male 37.0-53.0%, Female 34.5-46.5% MCV M/F 80-100 fL MCH M/F 28.0-34.0 pg MCHC M/F 30.0-36.0 gm/dL RDW M/F 11.3-14.7% Platelet M/F 130-400 thou/cumm Reported: Within 24 hours Hemosiderin, Urine Order code: 2060 Preferred specimen: 4.5 mL aliquot from a well-mixed random urine. First morning collection is preferred. Minimum specimen: 1.0 mL random urine. Unacceptable: Specimens in preservative. Transport temp: Frozen Method: Microscopic Stain Unit code: 818020 CPT Code(s): 83070 Ref range: Negative Reported: 1-2 days S1 0 Heparin Anti-Xa Order code: 2287 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube. Blue top tube must be filled to completion to ensure proper blood to anticoagulant ratio. Mix the tube immediately by gentle inversion at least 6 times. Centrifuge immediately and remove the top two-thirds of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer plasma into a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Heparin Anti-Xa levels should be drawn six hours after initiation of unfractionated heparin therapy or change in dose, whereas, with low molecular weight heparin, levels should be drawn six hours after administration when given once daily and three to four hours when administered twice daily. Unacceptable: Grossly hemolyzed specimens, clotted whole blood. Transport temp: Frozen Method: Chromogenic Unit code: 202870 CPT Code(s): 85520 Ref range: Therapeutic range: Heparin (unfractionated): 0.3-0.7 IU/mL Enoxaparin (Lovenox® or other LMWH) Twice daily dosing: 0.6-1.0 IU/mL Once daily dosing: 1.0-1.9 IU/mL Reported: Within 24 hours Heparin Associated Antibody Detection See: Heparin-Induced Thrombocytopenia (HIT) Antibodies 10-241 Test List BBPL Directory of Services Heparin-Induced Thrombocytopenia (HIT) Antibodies, PF4 IgG/IgM/IgA Order code: 80750 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 1.0 mL plasma, light blue (sodium citrate) or yellow (ACD solution A or B) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Unacceptable: Heparinzed plasma. Microbially contaminated, hemolyzed, icteric, lipemic, or heat-inactivated sera may give inconsistent results. Transport temp: CRITICAL FROZEN Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 818351 CPT Code(s): 86022 Ref range: 0.399 OD or less Reported: 1-2 days Heparin-Induced Thrombocytopenia (HIT) Antibodies, PF4 IgG/IgM/IgA with Reflex to Serotonin Release Assay (Heparin Dependent Platelet Antibody), Unfractionated Heparin Order code: 81848 Preferred specimen: 3.0 mL serum, gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 2.0 mL serum Notes: Positive ELISA results are relatively non-specific for a clinical diagnosis of HIT. If ELISA result is positive, then Serotonin Release Assay (a functional assay with greater specificity for a clinical diagnosis of HIT syndrome) will be added at an additional charge. Unacceptable: Plasma or contaminated specimens. Microbially contaminated, heat-inactivated, hemolyzed, icteric, or lipemic sera may give inconsistent results. Transport temp: CRITICAL FROZEN Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Serotonin Release Assay Unit code: 818348 CPT Code(s): 86022 Ref range: Heparin-Induced Thrombocytopenia Antibodies: 0.399 OD or less Serotonin Release Assay (Heparin Dependent Platelet Antibody), Unfractionated Heparin: By report Reported: 1-10 days Hepatic Function Panel A Order code: 1129 Preferred specimen: 2.0 mL serum, SST or red top tube Minimum specimen: 1.0 mL serum Notes: Test includes: Albumin Alkaline Phosphatase Direct Bilirubin SGOT (AST) SGPT (ALT) Total Bilirubin Total Protein Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: See individual tests Unit code: 90126 CPT Code(s): 80076 Ref range: Albumin Alkaline Phosphatase Direct Bilirubin SGOT (AST) SGPT (ALT) Total Bilirubin Total Protein 3.5-5.5 g/dL 30-140 U/L 0.0-0.4 mg/dL 0-41 U/L 0-45 U/L 0.2-1.2 mg/dL 6.0-8.5 g/dL Reported: Within 24 hours Hepatitis A Antibody, IgM Order code: 5230 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111900 CPT Code(s): 86709 Ref range: Negative Reported: 1-3 days Test List 10-242 S1 0 BBPL Directory of Services Hepatitis A Antibody, Total with reflex to IgM Order code: 5231 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Notes: If Hepatitis A Antibody Total is positive, then Hepatitis A Antibody IgM will be added. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111898 CPT Code(s): 86708 Ref range: Negative Reported: 1-3 days Hepatitis A Virus Panel (Hepatitis A Total & IgM) Order code: 94107 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Test includes Hepatitis A Antibodies, Total and IgM. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94107 CPT Code(s): 86708, 86709 Ref range: Negative Reported: 1-3 days Hepatitis B Core Antibody, IgM Order code: 5212 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111810 CPT Code(s): 86705 S1 0 Ref range: Negative Reported: 1-3 days Hepatitis B Core Antibody, Total Order code: 5220 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoasay Unit code: 111840 CPT Code(s): 86704 Ref range: Negative Reported: 1-3 days Hepatitis B Drug Resistance Panel See: Hepatitis B Virus Genotyping Hepatitis B Panel Order code: 5334 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Surface Antibody Hepatitis B Core Antibody, Total Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94110 CPT Code(s): 86704, 86706, 87340 Ref range: Negative Reported: 1-3 days 10-243 Test List BBPL Directory of Services Hepatitis B Panel II Order code: 94113 Preferred specimen: 5.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 3.5 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Surface Antibody Hepatitis B Core Antibody, Total Hepatitis B Core Antibody, IgM Hepatitis Be Antigen Hepatitis Be Antibody Unacceptable: Grossly hemolyzed, lipemic, or heat-inactivated specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay/Enzyme Immunoassay Unit code: 94113 CPT Code(s): 86704, 86705, 86706, 86707, 87340, 87350 Ref range: Negative Reported: 1-3 days Hepatitis B Surface Antibody Order code: 5235 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111880 CPT Code(s): 86706 Ref range: Negative Reported: 1-3 days Hepatitis B Surface Antibody, Quantitative Order code: 5225 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum S1 0 Unacceptable: Obvious microbial contamination. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111885 CPT Code(s): 86706 Ref range: 4 IU/L or less.......Negative 5 to 11 IU/L.........Indeterminate 12 to 1,000 IU/L.....Positive Results greater than or equal to 12 IU/L implies immunity to HBV. Reported: 1-3 days Hepatitis B Surface Antigen Order code: 5210 Preferred specimen: 1.5 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111800 CPT Code(s): 87340 Ref range: Negative Reported: 1-3 days Test List 10-244 BBPL Directory of Services Hepatitis B Virus DNA, Quantitative PCR Order code: 83160 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells within 24 hours, transfer to plastic transport tube and freeze. Minimum specimen: 0.75 mL serum or plasma Notes: The quantitative range of this assay is 1.3-8.2 log IU/mL (20-170,000,000 IU/mL). 1 IU/mL of HBV DNA is approximately 5.82 copies/mL. The limit of quantification for this DNA assay is 1.3 log IU/mL (20 IU/mL). If the assay DID NOT DETECT the virus, the test result will be reported as "<1.3 log IU/mL (<20 IU/mL)." If the assay DETECTED the presence of the virus but was not able to accurately quantify the number of IU the test result will be reported as "Not Quantified." Specimens received with less than minimum volume for testing will automatically be run with a dilution according to the guidelines below: -Specimens with 325-650 µL will be diluted resulting in a modification of the quantitative range of the assay to 1.6-8.5 log IU/mL (41-350,000,000 IU/mL). -Specimens with 130-325 µL will be diluted resulting in a modification of the quantitative range of the assay to 2.0-8.9 log IU/mL (102-870,000,000 IU/mL). This test is intended for use in conjunction with clinical presentation and other laboratory markers as an indicator of disease prognosis. This test is also used as an aid in accessing viral response to treatment as measured by changes in HBV DNA levels. This assay should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular Tissue-Based Products (HCT/P). Other acceptable: 2.0 mL plasma, lavender (EDTA). Remove plasma from cells within 24 hours, transfer to a plastic transport tube and freeze. Unacceptable: Heparinized specimens. Transport temp: Frozen Method: Real-Time Polymerase Chain Reaction Unit code: 818300 CPT Code(s): 87517 Ref range: Not detected Reported: 2-4 days Hepatitis B Virus Genotyping Order code: 81805 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells within 24 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum of plasma Notes: Please submit most recent viral load and test date if avaiable. This test may be unsuccessful if the HBV viral load is less than log 3.0 or 1,000 IU/mL. Both the HBV RT polymerase and the HBsAg encoding regions are sequenced. Resistance and surface antigen mutations are reported. In addition, the eight major HBV genotypes (A, B, C, D, E, F, G and H) are identified. Mutations in viral sub-populations below 20 percent of total may not be detected. S1 0 Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 24 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Heparinized specimens. Transport temp: Frozen Method: Polymerase Chain Reaction/Sequencing Unit code: 818305 CPT Code(s): 87912 Ref range: By report Reported: Within 10 days Hepatitis B Virus PreVaccine Screen Order code: 5338 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.7 mL serum Notes: Test includes: Hepatitis B Core Antibody, Total Hepatitis B Surface Antibody Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94115 CPT Code(s): 86704, 86706 Ref range: Negative Reported: 1-3 days 10-245 Test List BBPL Directory of Services Hepatitis Be Virus Antibody Order code: 83100 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.4 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Non-EDTA plasma specimens Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 818500 CPT Code(s): 86707 Ref range: Negative Reported: 2-5 days Hepatitis Be Virus Antigen Order code: 83110 Preferred specimen: 1.5 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.6 mL serum or plasma Other acceptable: 1.5 mL plasma, lavender (EDTA) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Non-EDTA plasma specimens Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 818550 CPT Code(s): 87350 Ref range: Negative Reported: 2-5 days Hepatitis C Antibody Order code: 5237 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay S1 0 Unit code: 112024 CPT Code(s): 86803 Ref range: Negative Reported: 1-3 days Hepatitis C Antibody with Reflex to Hepatitis C RNA Quantitative PCR Order code: 5236 Preferred specimen: 2.5 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Serum should be received in laboratory within 72 hours of collection, refrigerated. Minimum specimen: 1.7 mL serum Notes: If Hepatitis C Antibody is positive, Hepatitis C RNA Quantitative PCR will be added. Unacceptable: Heparinized specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay/Polymerase Chain Reaction Unit code: 112026 CPT Code(s): 86803 Ref range: Negative Reported: 2-5 days Hepatitis C RIBA Supplemental See: Hepatitis C RNA, Quantitative PCR Test List 10-246 BBPL Directory of Services Hepatitis C RNA, Qualitative PCR Order code: 37100 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 1.5 mL serum or plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 3.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Heparinized specimens. Transport temp: Frozen Method: Polymerase Chain Reaction Unit code: 537100 CPT Code(s): 87521 Ref range: Negative. The lower limit of detection is 50 IU/mL. Reported: 1-4 days Hepatitis C RNA, Quantitative PCR Order code: 37000 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.5 mL serum or plasma Notes: Also referred to as Hepatitis C Viral Load. Other acceptable: 3.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Heparinized specimens. Transport temp: Frozen Method: Polymerase Chain Reaction Unit code: 537000 CPT Code(s): 87522 Ref range: <50 IU/mL Reported: 1-4 days S1 0 Hepatitis C RNA, Quantitative PCR with Reflex to Genotype Order code: 37105 Preferred specimen: 4.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 2.0 mL serum or plasma Notes: If Hepatitis C RNA Quantitative result is greater than or equal to 50 IU/mL then Hepatitis C Virus Genotyping will be added. Other acceptable: 4.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Heparinized specimens. Transport temp: Frozen Method: Polymerase Chain Reaction/Nucleic Acid Sequencing Unit code: 537105 CPT Code(s): 87522 Ref range: Hepatitis C RNA Quantitative: <50 IU/mL Reported: 1-4 days Hepatitis C Viral Load See: Hepatitis C RNA, Quantitative PCR Hepatitis C Virus Genotype Order code: 37110 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 2.0 mL serum or plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 3.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Heparinized plasma. Transport temp: Frozen Method: Polymerase Chain Reaction Unit code: 537110 CPT Code(s): 87902 Ref range: By report Reported: 1-7 days 10-247 Test List BBPL Directory of Services Hepatitis Delta Antibody Order code: 83150 Preferred specimen: 1.0 mL serum, SST or red top tube. Remove serum from cells and transfer to a plastic transport tube ASAP. Freeze. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, light blue (sodium citrate), green (sodium or lithium heparin), or lavender (EDTA) top tube. Remove plasma from cells and transfer to a plastic transport tube ASAP. Freeze. Unacceptable: Hemolyzed or lipemic specimens. Ambient specimens. Transport temp: Frozen Method: Enzyme Immunoassay Unit code: 818700 CPT Code(s): 86692 Ref range: Negative Reported: 1-7 days Hepatitis Delta Antigen Order code: 83140 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 1 hour of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL serum Unacceptable: Grossly hemolyzed or lipemic specimens. Thawed specimens. Transport temp: CRITICAL FROZEN Method: Qualitative Enzyme-Linked Immunosorbent Assay Unit code: 818695 CPT Code(s): 87380 Ref range: By report Reported: 3-9 days Hepatitis E Virus Antibody, IgG Order code: 81555 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 0.5 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Specimens containing particulate material. Transport temp: Refrigerated Method: Qualitative Enzyme-Linked Immunosorbent Assay Unit code: 818555 CPT Code(s): 86790 Ref range: Negative Reported: 1-8 days Hepatitis E Virus Antibody, IgM Order code: 81556 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 0.5 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Specimens containing particulate material. Transport temp: Refrigerated Method: Qualitative Enzyme-Linked Immunosorbent Assay Unit code: 818556 CPT Code(s): 86790 Ref range: Negative Reported: 1-8 days Test List 10-248 S1 0 BBPL Directory of Services Hepatitis Immunity Panel Order code: 5336 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.7 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Surface Antibody Hepatitis B Core Antibody, Total Hepatitis C Antibody Hepatitis A Antibody, Total (If positive reflexes to Hepatitis A, IgM) Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94187 CPT Code(s): 86704, 86706, 86708, 86803, 87340 Ref range: Negative Reported: 1-3 days Hepatitis Panel I Order code: 5330 Preferred specimen: 2.5 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Surface Antibody Hepatitis B Core Antibody Total Hepatitis A Antibody,IgM Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94100 CPT Code(s): 86704, 86706, 86709, 87340 Ref range: Negative Reported: 1-3 days S1 0 Hepatitis Panel II Order code: 5335 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.7 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Surface Antibody Hepatitis B Core Antibody, Total Hepatitis A Antibody, Total (If positive reflexes to Hepatitis A, IgM) Hepatitis C Antibody Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94186 CPT Code(s): 86704, 86706, 86708, 86803, 87340 Ref range: Negative Reported: 1-3 days Hepatitis Panel III Order code: 5337 Preferred specimen: 5.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 3.5 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Surface Antibody Hepatitis B Core Antibody, Total Hepatitis B Core Antibody, IgM Hepatitis Be Antigen Hepatitis Be Antibody Hepatitis C Antibody Transport temp: Refrigerated Method: Chemiluminescent Immunoassay/Enzyme Immunoassay Unit code: 94111 CPT Code(s): 86704, 86705, 86706, 86707, 86803, 87340, 87350 Ref range: Negative Reported: 1-3 days 10-249 Test List BBPL Directory of Services Hepatitis Panel, Acute Order code: 5331 Preferred specimen: 2.5 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Core Antibody, IgM Hepatitis A Antibody, IgM Hepatitis C Antibody Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94101 CPT Code(s): 80074 Ref range: Negative Reported: 1-3 days Hepatitis Panel, Comprehensive I Order code: 5333 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.7 mL serum Notes: Test includes: Hepatitis B Surface Antigen Hepatitis B Surface Antibody Hepatitis B Core Antibody, Total Hepatitis A Antibody, IgM Hepatitis C Antibody Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 94105 CPT Code(s): 86704, 86706, 86709, 86803, 87340 Ref range: Negative Reported: 1-3 days HER-2/neu Quantitative by ELISA Order code: 81882 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.2 mL serum Unacceptable: Hemolyzed or thawed specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 818802 CPT Code(s): 83950 Ref range: By report Reported: 3-8 days HER2 Analysis Order code: 35702 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block. Specimen must be fixed in 10% neutral buffered formalin for 6-72 hours. Other acceptable: Needle biopsy fixed a minimum of 1 hour in 10% neutral buffered formalin. Unacceptable: Fixatives other than 10% neutral buffered formalin are not acceptable. Transport temp: Room temperature Method: Immunohistochemistry (IHC) and Fluorescence in situ Hybridization (FISH) Unit code: 535702 CPT Code(s): 88361, 88367 (x2) Ref range: By report Reported: 3-7 days HER2 Analysis, Gastroesophageal Order code: 35704 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block. Specimen must be fixed in 10% neutral buffered formalin for 6-72 hours. Other acceptable: Needle biopsy fixed a minimum of 1 hour in 10% neutral buffered formalin. Transport temp: Room temperature Method: Immunohistochemistry (IHC) and Fluorescence in situ Hybridization (FISH) Unit code: 535704 CPT Code(s): 88361, 88367 (x2) Ref range: By report Reported: 3-7 days Test List 10-250 S1 0 BBPL Directory of Services HER2 by FISH Order code: 35700 Preferred specimen: Formalin-fixed, paraffin-embedded tissue. Submit specimen at room temperature, do not expose to excessive heat. Notes: Call Molecular Pathology Department for further instructions. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 535700 CPT Code(s): 88367 (x2) Ref range: Ratio >2.00 indicates over-amplification of Her2/Neu. Reported: 3-7 days HER2 by FISH, Gastroesophageal Order code: 35703 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block. Specimen must be fixed in 10% neutral buffered formalin for 6-72 hours. Other acceptable: Needle biopsy fixed a minimum of 1 hour in 10% neutral buffered formalin. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 535703 CPT Code(s): 88361, 88367 (x2) Ref range: By report Reported: 3-7 days Herpes Simplex Virus (HSV) Type 1 & 2 Antibodies, IgG Order code: 83210 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Other acceptable: Serum from umbilical cord blood is an acceptable specimen type. Unacceptable: Urine. CSF. Contaminated, heat-inactivated, or hemolyzed specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay S1 0 Unit code: 818950 CPT Code(s): 86694 Ref range: 0.89 IV or less: Not Detected 0.90-1.09 IV: Indeterminate - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Detected Reported: 1-2 days Herpes Simplex Virus (HSV) Type 1 & 2 Antibodies, IgG & IgM Order code: 83225 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or convalescent." Unacceptable: Contaminated, heat-inactivated, or hemolyzed specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Chemiluminescent Immunoassay Unit code: 819201 CPT Code(s): 86694 (x2) Ref range: See individual tests. Reported: 1-2 days 10-251 Test List BBPL Directory of Services Herpes Simplex Virus (HSV) Type 1 & 2 Antibodies, IgM Order code: 83220 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Unacceptable: Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 819150 CPT Code(s): 86694 Ref range: 0.89 IV or less: Not Detected 0.90-1.09 IV: Indeterminate - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Detected - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. Reported: 1-2 days Herpes Simplex Virus (HSV) Type 1 & 2 Glycoprotein G-Specific Antibodies, IgG by ELISA Order code: 3309 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Unacceptable: Lipemic, hemolyzed, contaminated, or heat-inactivated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay (HerpeSelect®) Unit code: 353090 CPT Code(s): 86695, 86696 Ref range: Herpes Simplex Virus 1 Glycoprotein G-Specific Antibody, IgG <0.90 IV: Negative - No significant level of detectable IgG antibody to HSV type 1 glycoprotein G. 0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 1. Repeat testing in 10-14 days may be helpful. >1.10 IV: Positive - IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection. Herpes Simplex Virus 2 Glycoprotein G-Specific Antibody, IgG <0.90 IV: Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G. 0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-14 days may be helpful. >1.10 IV: Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection. S1 0 Reported: 1-5 days Herpes Simplex Virus (HSV) Type 1 & 2 Glycoprotein G-Specific Antibodies, IgG by Immunoblot Order code: 81895 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent." Minimum specimen: 0.1 mL serum Unacceptable: Contaminated, heat-inactivated, hemolyzed, or hyperlipemic specimens. Transport temp: Refrigerated Method: Qualitative Immunoblot Unit code: 818955 CPT Code(s): 86695, 86696 Ref range: By report Reported: 1-8 days Herpes Simplex Virus (HSV) Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA Order code: 3308 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Unacceptable: Lipemic, hemolyzed, contaminated, or heat-inactivated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay (HerpeSelect®) Unit code: 353088 CPT Code(s): 86695 Ref range: <0.90 IV: Negative - No significant level of detectable IgG antibody to HSV type 1 glycoprotein G. 0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 1. Repeat testing in 10-14 days may be helpful. >1.10 IV: Positive - IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection. Reported: 1-5 days Test List 10-252 BBPL Directory of Services Herpes Simplex Virus (HSV) Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA Order code: 3310 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Unacceptable: Lipemic, hemolyzed, contaminated, or heat-inactivated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay (HerpeSelect®) Unit code: 353089 CPT Code(s): 86696 Ref range: <0.90 IV: Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G. 0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-14 days may be helpful. >1.10 IV: Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection. Reported: 1-5 days Herpes Simplex Viruses (HSV) DNA Order code: 38255 Preferred specimen: Collect external anogenital lesion specimen or other vesicular lesion specimen using universal transport media kit. Transport refrigerated. Or: 1.0 mL serum, red top tube or SST or plasma, lavender (EDTA) top tube. Remove serum or plasma from cells, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL serum, plasma, CSF, SurePath media, or ThinPrep media. Notes: Specimen source is required. Record source on test request form. This assay will simultaneously detect and differentiate between HSV 1 and HSV 2. Other acceptable: 1.0 mL CSF in sterile container, frozen. Specimens submitted in SurePath media, ThinPrep media, or Aptima swab, refrigerated. Unacceptable: Heparinized specimens, non-sterile or leaking containers. Transport temp: Swab, universal transport media, SurePath media, ThinPrep media, or Aptima swab: Refrigerated All other specimens: Frozen Method: Polymerase Chain Reaction Unit code: 538255 CPT Code(s): 87529 (x2) Ref range: Not Detected Reported: 1-7 days S1 0 Herpes Virus 6 Antibody, IgG Order code: 83270 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent". Unacceptable: Hemolyzed, lipemic, contaminated or heat-inactivated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 819450 CPT Code(s): 86790 Ref range: 0.89 IV or less: Negative - No significant level of detectable HHV-6 IgG antibody. 0.90-1.10 IV: Equivocal - Questionable presence of HHV-6 IgG antibody. Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgG antibody to HHV-6 detected, which may indicate current or past infection. Reported: 1-6 days 10-253 Test List BBPL Directory of Services Hexagonal Phase Phospholipid Order code: 89390 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube. Blue top tube must be filled to completion to ensure a proper blood to anticoagulant ratio. Mix the tube immediately by gentle inversion at least 6 times to ensure adequate mixing of the anticoagulant with the blood. Citrated plasma specimens should be collected by double centrifugation. Centrifuge for 10 minutes and carefully remove the two-thirds of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma to a plastic transport tube, cap, and recentrifuge for 10 minutes. Use a second plastic pipette to remove the plasma, staying clear of the platelets at the bottom of the tube. Transfer the plasma to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Avoid warfarin (Coumadin) therapy for two weeks and heparin therapy for two days prior to the test. Do not draw from an arm with a heparin lock or heparnized catheter. Unacceptable: Gross hemolysis, clotted specimens, non-frozen specimens, specimens collected in tubes other than 3.2% citrate. Transport temp: Frozen Method: Clotting Time Unit code: 819390 CPT Code(s): 85598 Ref range: Patients with a prolonged aPTT or aPTT-LA screening test: Reduction of the aPTT result by more than eight seconds (test result more than eight seconds) as the result of adding hexagonal phase phospholipid (HPP) is consistent with the presence of a phospholipid-dependent inhibitor (lupus anticoagulant). Failure of the HPP to reduce the aPTT result (test result less than eight seconds) can be interpreted as an indication of the presence of one or more specific factor inhibitors. Reported: 2-7 days Hexosaminidase A Percent & Total, Leukocytes Order code: 81942 Preferred specimen: 3.0 mL whole blood, yellow (ACD solution A or B) top tube. Do not transfer whole blood to other containers. Transport original tube at room temperature within 48 hours of collection. Minimum specimen: 1.0 mL whole blood Notes: Clinical information is needed for appropriate interpretation. A Patient History for Biochemical Genetics form along with test request form must be submitted with specimen. This test is used for the diagnosis of Tay-Sachs disease and can also be used to identify carriers for this disorder. Carrier screening is offered to individuals of Ashkenazi Jewish descent because of the high incidence of the disease in this population. Unacceptable: Whole blood received greater than 3 days from collection. Grossly hemolyzed specimens. Frozen specimens. Transport temp: Room temperature Method: Fluorometry Unit code: 819402 S1 0 CPT Code(s): 83080 Ref range: Greater than or equal to 63 percent Reported: 2-9 days Hexosaminidase A Percent & Total, Serum Order code: 81941 Preferred specimen: 3.0 mL serum, red top tube. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.2 mL serum Notes: Clinical information is needed for appropriate interpretation. A Patient History for Biochemical Genetics form along with test request form must be submitted with specimen. This test is used for the diagnosis of Tay-Sachs disease and can also be used to identify carriers for this disorder. Carrier screening is offered to individuals of Ashkenazi Jewish descent because of the high incidence of the disease in this population. Pregnant women or women using oral contraceptives cannot be tested using serum because of high false-positives rates. In serum samples, false positives can also be caused by several other conditions, including severe liver disease and autoimmune diseases. Testing in leukocytes should be used in these cases. Transport temp: Frozen Method: Flourometry Unit code: 819401 CPT Code(s): 83080 Ref range: Hexosaminidase A: 55-76 percent Hexosaminidase Total: 800-1400 nmol hydrolyzed/hr/mL Reported: 2-9 days HGA (Human Granulocytic Anaplasmosis) See: Anaplasma Phagocytophilum (HGA) Antibodies, IgG & IgM HGE (Human Granulocytic Ehrlichiosis) See: Anaplasma Phagocytophilum (HGA) Antibodies, IgG & IgM HGH See: Growth Hormone Test List 10-254 BBPL Directory of Services HIAA (Hydroxyindoleacetic Acid) See: 5-HIAA (5-Hydroxyindoleacetic Acid), Urine Hirsutism Profile Order code: 15525 Preferred specimen: 3.0 mL serum, red top tube. Avoid use of SST. Remove serum from cells ASAP and aliquot 1.0 mL serum into three separate transport tubes. Freeze one of the transport tubes and refrigerate the other two tubes. Minimum specimen: 1.5 mL serum (0.5 mL in each aliquot tube) Notes: Test includes: Androstenedione DHEA Sulfate Testosterone, Free, Female Unacceptable: Plasma. Gross hemolysis, lipemia, or separator tubes or gels. Transport temp: 1 serum aliquot tube frozen 2 serum aliquot tubes refrigerated Method: Chemiluminescent Immunoassay/Liquid Chromatography/Tandem Mass Spectrometry Unit code: 819574 CPT Code(s): 82157, 82627, 84402 Ref range: By report Reported: 1-4 days Histamine, Blood Order code: 83280 Preferred specimen: 1.0 mL whole blood, green (sodium or lithium heparin) top tube, frozen. Minimum specimen: 0.5 mL whole blood Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Nonfrozen samples. Transport temp: CRITICAL FROZEN Method: Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 819600 CPT Code(s): 83088 Ref range: 180-1800 nmmol/L S1 0 Reported: 1-5 days Histamine, Plasma Order code: 81961 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Specimen must be collected in a pre-chilled tube. Collect on ice. Centrifuge at 2-8 C and separate upper two-thirds of plasma within 20 minutes. Transfer plasma to a plastic transport tube and freeze immediately. Minimum specimen: 0.5 mL plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Enzyme Immunoassay Unit code: 819601 CPT Code(s): 83088 Ref range: 0-8 nmol/L Reported: 1-6 days Histamine, Urine Order code: 83290 Preferred specimen: 4.0 mL urine aliquot from a well-mixed random or 24-hour urine collection. Refrigerate 24-hour specimen during collection. Urine must be collected in a plastic container and frozen immediately after the collection period. Transfer urine aliquot into a plastic transport container and freeze. Record total volume and hours of collection on both the urine container and test request form Minimum specimen: 1.0 mL urine aliquot Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: Samples preserved with HCl are acceptable for this test if frozen immediately. Unacceptable: Room temperature specimens. Transport temp: CRITICAL FROZEN Method: Enzyme Immunoassay Unit code: 819650 CPT Code(s): 83088 Ref range: Histamine, Urine - ratio to CRT: 0-450 nmol/g crt Histamine, Urine, Excretion - 24 hr: 0-60 µg/day Reported: 1-6 days 10-255 Test List BBPL Directory of Services Histone Antibodies See: Anti-Histone Antibodies Histoplasma Antibodies by CF Order code: 83320 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Minimum specimen: 0.25 mL serum Unacceptable: Severely lipemic or contaminated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Complement Fixation Unit code: 819850 CPT Code(s): 86698 (x2) Ref range: Histoplasma Mycelia Antibody by CF <1:8 Histoplasma Yeast Antibody by CF <1:8 Reported: 1-3 days Histoplasma Antibody by ID Order code: 81951 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Unacceptable: Body fluids Transport temp: Refrigerated Method: Qualitative Immunodiffusion Unit code: 819851 CPT Code(s): 86698 Ref range: None detected Reported: 2-4 days Histoplasma Antigen by EIA, Serum Order code: 81985 Preferred specimen: 2.0 mL serum, SST or red top tube. Minimum specimen: 1.0 mL serum Unacceptable: Urine (refer to order code 81954 Histoplasma Galactomannan Antigen Quantitative by EIA, Urine). Specimens other than serum. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 819855 CPT Code(s): 87385 Ref range: Negative - Less than 2.0 U/mL Weak Positive - 2.0-4.0 U/mL Positive - 4.1 or greater U/mL Reported: 1-2 days Histoplasma Galactomannan Antigen Quantitative by EIA, Urine Order code: 81954 Preferred specimen: 2.0 mL aliquot from a well-mixed random urine transported in a plastic urine container. Minimum specimen: 2.0 mL urine Unacceptable: Specimens other than urine. Urine in boric acid. Serum (refer to order code 81985 Histoplasma Antigen by EIA, Serum) Transport temp: Refrigerated Method: Quantitative Enzyme Immunoassay Unit code: 819854 CPT Code(s): 87385 Ref range: Not Detected Interpretive Data: Less than 3.2 ng/mL=Detected (below the limit of quantification) 3.2-20.0 ng/mL=Detected Greater than 20.0 ng/mL=Detected (above the limit of quantification) The quantitative range of this assay is 3.2-20.0 ng/mL. Antigen concentrations between 0.4-3.1 or>20.0 ng/mL fall outside the linear range of the assay and cannot be accurately quantified. This EIA test should be used in conjunction with other diagnostic procedures, including microbiological culture, histological examination of biopsy samples, and/or radiographic evidence, to aid in the diagnosis of histoplasmosis. Reported: 1-2 days Test List 10-256 S1 0 BBPL Directory of Services HIV Phenotype Comprehensive See: Human Immunodeficiency Virus (HIV) Phenotype Comprehensive HIV-1 Antibody, Confirmation Western Blot See: Human Immunodeficiency Virus 1 Antibody, Confirmation Western Blot HIV-1 Antibody, Reflex to Western Blot See: Human Immunodeficiency Virus Type 1 Antibody with Reflex to Confirmation by Western Blot HIV-1 Genotyping See: Human Immunodeficiency Virus 1, Genotyping HIV-1 RNA, Quantitative PCR See: Human Immunodeficiency Virus 1 RNA, Quantitative PCR HIV-1/2 Antibodies, EIA Order code: 5801 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 112101 CPT Code(s): 86703 Ref range: Non-Reactive Reported: 1-3 days S1 0 HIV-2 Antibody, Reflex to Confirmation See: Human Immunodeficiency Virus 2 (HIV-2) Antibody with Reflex to HIV-2 Supplemental HLA A & B Genotyping Order code: 82205 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Unacceptable: Specimens collected in green (sodium or lithium heparin) top tubes. Transport temp: Room temperature Method: Polymerase Chain Reaction/Sequence Specific Oligonucleotide Probe Hybridization Unit code: 820265 CPT Code(s): 81380 (x2) Ref range: By report Reported: 3-7 days HLA Class I (ABC) by Next Generation Sequencing Order code: 82057 Preferred specimen: 4.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.0 mL whole blood Unacceptable: Clotted, grossly hemolyzed, or heparinized specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Massive Parallel Sequencing Unit code: 820257 Ref range: By report Reported: 8-15 days 10-257 Test List BBPL Directory of Services HLA Class II (DRB1 and DQB1) by Next Generation Sequencing Order code: 82306 Preferred specimen: 4.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.0 mL whole blood Unacceptable: Clotted, grossly hemolyzed, or heparinized specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Massive Parallel Sequencing Unit code: 820306 Ref range: By report Reported: 8-15 days HLA-A Genotype Order code: 82206 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Unacceptable: Specimens collected in green (sodium or lithium heparin) top tubes. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Sequence Specific Oligonucleotide Probe Hybridization Unit code: 820266 CPT Code(s): 81380 Ref range: By report Reported: 3-7 days HLA-A Sequencing Order code: 82025 Preferred specimen: 5.0 mL whole blood, yellow (ACD Solution A) or lavender (EDTA) top tube. Minimum specimen: 1.5 mL whole blood Unacceptable: Heparinized, clotted, or frozen whole blood specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Nucleic Acid Sequencing Unit code: 820253 CPT Code(s): 81380 S1 0 Ref range: By report Reported: 7-11 days HLA-B Genotype Order code: 82207 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Unacceptable: Specimens collected in green (sodium or lithium heparin) top tubes. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Sequence Specific Oligonucleotide Probe Hybridization Unit code: 820267 CPT Code(s): 81380 Ref range: By report Reported: 3-7 days HLA-B27 Order code: 35427 Preferred specimen: 5.0 mL whole blood, lavender (EDTA), green (sodium heparin), or yellow (ACD Solution A or B) top tube. Maintain specimen at room temperature. Do not refrigerate or freeze. Specimen must be received in the laboratory within 72 hours of collection. Minimum specimen: 1.5 mL whole blood Notes: The HLA B27 Antigen is present in 8% of Caucasian and 3% of black populations. This antigen is seen with a frequency of 90% in patients with Ankylosing Spondylitis and a frequency of 80% in patients with Reiter's disease. Unacceptable: Frozen or refrigerated specimens. Specimens older than 72 hours. Clotted or hemolyzed specimens. Transport temp: Room temperature Method: Flow Cytometry Unit code: 535427 CPT Code(s): 86812 Ref range: Negative Reported: 1-3 days Test List 10-258 BBPL Directory of Services HLA-B5701 Genotyping Order code: 82029 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Transport temp: Refrigerated Method: Polymerase Chain Reaction/Fluorescence Monitoring Unit code: 820290 CPT Code(s): 81381 Ref range: By report Reported: 4-10 days HLA-DR Genotyping Order code: 82031 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Unacceptable: Specimens drawn in green (sodium or lithium heparin) tubes. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Sequence Specific Oligonucleotide Probe Hybridization Unit code: 820309 CPT Code(s): 81382 Ref range: By report Reported: 3-7 days Homocysteine, Total Order code: 1511 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 1 hour of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Specimens should be stored on ice if unable to separate from cells within 1 hour. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (lithium heparin) top tube. Remove plasma from cells within 1 hour of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay S1 0 Unit code: 114250 CPT Code(s): 83090 Ref range: 3.7-13.9 umol/L Reported: Within 24 hours Homovanillic Acid (HVA), Urine Order code: 83335 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random collection. Refrigerate 24-hour specimen during collection. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Patient should abstain from medications for 72 hours prior to collection of specimen. Transport temp: Refrigerated Method: High Performance Liquid Chromatography Unit code: 820400 CPT Code(s): 83150 Ref range: By report Reported: 1-4 days HPV See: Human Papillomavirus (HPV) DNA Probe, High Risk Human Papillomavirus (HPV) DNA Probe, High Risk with Reflex to Genotypes 16, and 18,45 Human Papillomavirus (HPV) DNA Probe, High/Low Risk Human Papillomavirus (HPV) High Risk Genotypes, 16 and 18,45 Human Papillomavirus (HPV) Type by PCR, Tissue 10-259 Test List BBPL Directory of Services HSV See: Herpes Simples Virus DFA with Reflex to Herpes Simplex Virus Culture Herpes Simplex Virus Type 1 & 2 Antibodies, IgG Herpes Simplex Virus Type 1 & 2 Antibodies, IgM Herpes Simplex Virus Type 1 & 2 Antibodies, IgG & IgM Herpes Simplex Virus Type 1 & 2 Glycoprotein G-Specific Antibodies, IgG by ELISA Herpes Simplex Virus Type 1 & 2 Glycoprotein G-Specific Antibodies, IgG by Immunoblot Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA Herpes Simplex Virus Type 1 & 2 Molecular Detection Herpes Simplex Virus Type 1 & 2 PCR Herpes Simplex Viruses DNA Herpes Simplex Viruses PCR Human Chorionic Gonadotropin, (Beta-hCG) Qualitative, Pregnancy, Serum Order code: 1370 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111010 CPT Code(s): 84703 Reported: Within 24 hours Human Chorionic Gonadotropin, (Beta-hCG) Quantitative, Serum (Females) Order code: 1375 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111015 CPT Code(s): 84702 Ref range: Time Post Conception mIU/mL 1 week 5-50 2 weeks 40-1,000 3 weeks 100-5,000 4 weeks 600-10,000 5-6 weeks 1,500-100,000 00 7-8 weeks 16,000-200,0 2-3 months 12,000-300,000 2nd trimester 24,000-55,000 3rd trimester 6,000-48,000 S1 0 Reported: Within 24 hours Human Epididymis Protein 4 (HE4) Order code: 82075 Preferred specimen: 0.5 mL serum, red top tube or SST. Allow specimen to clot completely at room temperature. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.1 mL serum Notes: HE4 is to be used as an aid in monitoring recurrence of progressive disease in patients with epithelial ovarian cancer. Serial testing for patient HE4 results should be used in conjunction with other clinical methods for monitoring ovarian cancer. Values obtained with different assay methods should not be used interchangeably. Unacceptable: Hemolyzed or lipemic specimens. Transport temp: Frozen Method: Quantitative Enzyme Immunoassay Unit code: 820675 CPT Code(s): 86305 Ref range: 0-150 pmol/L Reported: 1-8 days Human Granulocytic Anaplasmosis (HGA) See: Anaplasma Phagocytophilum (HGA) Antibodies, IgG & IgM Human Granulocytic Ehrlichiosis (HGE) See: Anaplasma Phagocytophilum (HGA) Antibodies, IgG & IgM Human Growth Hormone See: Growth Hormone Test List 10-260 BBPL Directory of Services Human Immunodeficiency Virus (HIV) 1 Genotyping Order code: 82078 Preferred specimen: 4.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP (within 6 hours of collection). Transfer plasma to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 2.5 mL plasma Notes: This test may be unsuccessful if the plasma HIV-1 RNA viral load is less than 1,000 HIV-1 RNA copies per mL of plasma. Unacceptable: Serum, whole blood, or heparinized plasma. Specimens that are thawed or have been exposed to repeated freeze/thaw cycles. Transport temp: Frozen Method: Reverse Transcription Polymerase Chain Reaction/DNA Sequencing Unit code: 820078 CPT Code(s): 87901 Ref range: By report Reported: 3-7 days Human Immunodeficiency Virus (HIV) 1 RNA, Quantitative PCR Order code: 37205 Preferred specimen: 3.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 6 hours of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 2.5 mL plasma Notes: Quantitative range of this assay is 1.3-7.0 log copies/mL (20-10,000,000 copies /mL). Unacceptable: Serum or heparinized plasma. Specimens exposed to exceesive freeze/thaw cycles. Transport temp: Frozen Method: Real-Time Polymerase Chain Reaction Unit code: 537205 CPT Code(s): 87536 Reported: Within 7 days Human Immunodeficiency Virus (HIV) 1/2 Antibodies, EIA See: HIV-1/2 Antibodies, EIA S1 0 Human Immunodeficiency Virus (HIV) Phenotype Comprehensive Order code: 82095 Preferred specimen: 3.0 mL plasma, lavender top tube (EDTA). Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 3.0 mL plasma Notes: Indicate viral load on the test requisition. If viral load is less than 500 copies, testing may not be performed. Unacceptable: Nonfrozen specimens. Transport temp: CRITICAL FROZEN Method: Drug Susceptibility using HIV Culture Unit code: 820095 CPT Code(s): 87903, 87904 (x11) Ref range: By report Reported: 15-22 days Human Immunodeficiency Virus 2 (HIV-2) Antibody with Reflex to HIV-2 Supplemental Order code: 81955 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: If HIV-2 antibody screen is repeatedly reactive, then HIV-2 Antibody, Supplemental (an HIV antibody type differentiation assay), will be added at an additional charge. This assay should not be used for blood donor screening, associated reentry protocols, or for screening Human Cell, Tissues and cellular and tissue-based products (HCT/P). Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Heat-inactivated, cadaveric, severely hemolyzed, or lipemic specimens. Room temperature specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay/Qualitative Immunoassay Unit code: 819955 CPT Code(s): 86702 Ref range: Human Immunodeficiency Virus 2 Antibody: Negative Reported: 1-5 days 10-261 Test List BBPL Directory of Services Human Immunodeficiency Virus Type 1 Antibody with Reflex to Confirmation by Western Blot Order code: 81998 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: This assay should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P). If Human Immunodeficiency Virus Type 1 (HIV-1) Antibody screen is repeatedly reactive, then Human Immunodeficiency Virus Type 1 (HIV-1) Antibody Confirmation by Western Blot will be added. Additional charges apply. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Heat-inactivated, severely hemolyzed, or lipemic specimens. Transport temp: Refrigerated Method: Qualitative Chemiluminescent Immunoassay/Qualitative Western Blot Unit code: 819948 CPT Code(s): 86701 Ref range: Negative Reported: 1-2 days Human Immunodeficiency Virus Type 1 Antibody, Confirmation Western Blot Order code: 83334 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or light blue (sodium citrate) top tube. Remove plasma from cells ASAP or within 2 hours of collection. Unacceptable: Hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Western Blot Unit code: 819950 CPT Code(s): 86689 Ref range: Negative Reported: 1-3 days S1 0 Human Insulin Antibodies See: Insulin Antibodies Human Papillomavirus (HPV) DNA Probe, High Risk Order code: 53801 Preferred specimen: Cervical brush in Digene specimen transport media (STM); 4.0 mL ThinPrep or SurePath transport media; or cervical biopsy (2-5 mm section) placed immediately in 1.0 mL Digene specimen transport media (STM) and frozen. Minimum specimen: 1.0 mL Digene specimen transport media or 4.0 mL ThinPrep or SurePath media. Notes: Specimen Stability: Digene STM: Room temperature 2 weeks; Refrigerated 3 weeks; Frozen 3 months. ThinPrep media: Room temperature or refrigerated 3 months. SurePath: Room temperature or refrigerated 28 days. Transport temp: Digene STM, ThinPrep or SurePath media at room temperature; Frozen for cervical biopsy. Method: Nucleic Acid Probe Unit code: 538010 CPT Code(s): 87621 Ref range: Negative Reported: 1-5 days Human Papillomavirus (HPV) DNA Probe, High Risk with Reflex to Genotypes 16, and 18,45 Order code: 38012 Preferred specimen: Cervical brush in Digene specimen transport media (STM); 4.0 mL ThinPrep or SurePath transport media; or cervical biopsy (2-5 mm section) placed immediately in 1.0 mL Digene specimen transport media (STM) and frozen. Specimen Stability: Digene STM: Room temperature 2 weeks; Refrigerated 3 weeks; Frozen 3 months. ThinPrep media: Room temperature or refrigerated 3 months. SurePath: Room temperature or refrigerated 28 days. Minimum specimen: 1.0 mL Digene specimen transport media or 4.0 mL ThinPrep or SurePath media. Notes: If HPV High Risk Screen is positive, HPV Genotypes 16 and 18,45 will be added at an additional charge. Transport temp: Digene STM, ThinPrep or SurePath media at room temperature; Frozen for cervical biopsy. Method: Nucleic Acid Probe Unit code: 538012 CPT Code(s): 87621 Ref range: Negative Reported: 1-5 days Test List 10-262 BBPL Directory of Services Human Papillomavirus (HPV) DNA Probe, High/Low Risk Order code: 53800 Preferred specimen: Cervical brush in Digene specimen transport media (STM); 4.0 mL ThinPrep or SurePath transport media; or cervical biopsy (2-5 mm section) placed immediately in 1.0 mL Digene specimen transport media (STM) and FROZEN. Minimum specimen: 1.0 mL Digene specimen transport media or 4.0 mL ThinPrep or SurePath media. Notes: Specimen Stability: Digene STM: Room temperature 2 weeks; Refrigerated 3 weeks; Frozen 3 months. ThinPrep media: Room temperature or refrigerated 3 months. SurePath: Room temperature or refrigerated 28 days. Transport temp: Digene STM, ThinPrep or SurePath media at 2-30 C; Frozen for cervical biopsy. Method: Nucleic Acid Probe Unit code: 538000 CPT Code(s): 87621 (x2) Ref range: Negative Reported: 1-5 days Human Papillomavirus (HPV) High Risk Genotypes, 16 and 18,45 Order code: 38020 Preferred specimen: Cervical cells in liquid-based cytologyThinPrep® vial. Follow collection instructions for ThinPrep® device. Minimum specimen: 2 mL of ThinPrep® media. Transport temp: Room temperature Method: Nucleic Acid Amplification (NAA) Unit code: 538020 CPT Code(s): 87621 (x2) Ref range: By report Reported: 3-5 days Human Papillomavirus (HPV) Type by PCR, Tissue Order code: 82046 Preferred specimen: Tissue: Formalin-fixed, paraffin-embedded (FFPE) tissue biopsy. Formalin-fixed tissue must be embedded in a parrafin block within 72 hours of excision. Do not substitute other fixative for formalin. Do not submit frozen tissue. Minimum specimen: There must be enough tissue for at least four 10-micron sections. Notes: Test includes detection of HPV in tissue specimen, HPV typing for (6, 11), (16), (18, 45), and (31, 33, 35, 39). S1 0 Unacceptable: Insufficient tissue, improper fixative or fixation. Transport temp: Room temperature Method: Polymerase Chain Reaction Unit code: 820461 CPT Code(s): 87999 Ref range: By report Reported: 3-7 days Human T-Lymphotropic Virus (HTLV) Types I/II Antibodies Reflex to HTLV I/II Confirmation Order code: 82098 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: If HTLV I/II screen is repeatedly reactive, then HTLV I/II confirmation by Western Blot will be added at an additional charge. Other acceptable: 0.5 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or light blue (sodium citrate) top tube. Remove plasma from cells ASAP or wtihin 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Specimens containing particulate material. Transport temp: Refrigerated Method: Qualitative Enzyme-Linked Immunosorbent Assay/Qualitative Western Blot Unit code: 820498 CPT Code(s): 86790 Ref range: Negative Reported: 1-5 days 10-263 Test List BBPL Directory of Services Human T-Lymphotropic Virus (HTLV) Types I/II Antibodies, Western Blot Order code: 82551 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma. Notes: Order this test only when a specimen is repeatedly reactive for HTLV I or HTLV I/II antibodies. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or light blue (sodium citrate) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Qualitative Western Blot Unit code: 820551 CPT Code(s): 86689 Ref range: Negative Reported: 1-8 days Huntington Disease (HD) Mutation by PCR Order code: 82081 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Notes: A completed Huntington Disease specific consent form, signed by the patient (or legal guardian) and physician, is required for all specimens. HD consent form is available through BBPL Client Services. Testing for patients under the age of 18 years or fetal specimens is not offered. Presymptomatic patients are strongly encouraged to be tested through a counseling program approved by the Huntington Disease Society of America at (800) 345-4372. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Fragment Analysis Unit code: 820801 CPT Code(s): 81401 Ref range: Negative: This individual has two normal alleles; and therefore, is neither a carrier nor will be affected with Huntington disease. Reported: 7-10 days Hydrocodone See: Drug Confirmation, Quantitation Opiates, Serum or Plasma S1 0 Hydroxycorticosteroids (17) See: 17-Hydroxycorticosteroids, Urine Hydroxycorticosterone (18) See: 18-Hydroxycorticosterone Hydroxypregnenolone (17) See: 17-Hydroxypregnenolone Quantitative, Serum or Plasma Hydroxyprogesterone (17) See: 17-Hydroxyprogesterone Test List 10-264 BBPL Directory of Services Hypercoagulable Panel Order code: 90032 Preferred specimen: For Factor V Leiden Mutation, Prothrombin Gene Mutation, and MTHFR Gene Mutation tests: 5.0 mL whole blood, lavender (EDTA), light blue (sodium citrate), or yellow (ACD Solution A or B) top tubes, refrigerated. For Antithrombin Enzymatic, Protein C, and Protein S tests: 6.0 mL platelet-poor plasma, three 3.5 mL light blue (3.2% sodium citrate) top tubes. Remove platelet-poor plasma from cells, transfer 2.0 mL plasma aliquots into 3 separate plastic transport tubes and freeze immediately. Minimum specimen: 3.0 mL whole blood and 1.0 mL plasma per aliquot tube. Notes: Test includes: Factor V Leiden Mutation (G1691A) Prothrombin Gene Mutation (G20210A) MTHFR Gene Mutation Antithrombin, Enzymatic (Activity) Protein C, Total Antigen Protein S, Total Antigen Protein S Free, Antigen Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Serum, heparin anticoagulant, severely hemolyzed specimens, specimens stored at incorrect transport temperature. Transport temp: Whole blood: Refrigerated Plasma: CRITICAL FROZEN Method: See individual tests. Unit code: 90032 CPT Code(s): 81240, 81241, 81291, 85300, 85302, 85305, 85306 Ref range: See individual tests. Reported: 3-7 days Hypersensitivity Pneumonitis (Farmer's Lung Panel) Order code: 83435 Preferred specimen: 5.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection. Aliquot 2.5 mL serum into two separate transport tubes. Minimum specimen: 1.0 mL serum Notes: Testing includes antibodies directed at: Allergen, Epidermal & Animal Proteins, Feather Mix Allergen, Food, Beef Allergen, Food, Pork Allergen, Fungi & Mold, Phoma betae Aspergillus flavus Aspergillus fumigatus #1 Aspergillus fumigatus #2 Aspergillus fumigatus #3 Aspergillus fumigatus #6 Aureobasidium pullulans Micropolyspora faeni Pigeon Serum Saccharomonospora viridis Thermoactinomyces candidus Thermoactinomyces sacchari Thermoactinomyces vulgaris #1 S1 0 Unacceptable: Plasma. Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Quantitative Immunodiffusion/Quantitative ImmunoCAP® Fluorescent Enzyme Unit code: 821150 CPT Code(s): 86003 (x3), 86005, 86331 (x7), 86606 (x5) Ref range: By report Reported: 3-7 days Hypoglycemia Panel, Sulfonylureas Qualitative Order code: 82116 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Do not collect in SST. Minimum specimen: 0.4 mL serum or plasma Notes: This assay is used to evaluate hypoglycemia that may be caused from the ingestion of sulfonylurea drugs. Hypoglycemic drugs are detected (present) in this assay if the drug concentration is greater than the limit of detection (cut-off). The presence of hypoglycemic drug(s) indicates a recent ingestion. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Frozen Method: Qualitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 821165 CPT Code(s): 83788 Ref range: By report Reported: 1-6 days 10-265 Test List BBPL Directory of Services Ibuprin See: Ibuprofen Ibuprofen Order code: 83440 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Collect one hour after dosing. Timing of specimen collection: Draw between 60 and 90 minutes post-dose. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin) or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: High Performance Liquid Chromatography Unit code: 821200 CPT Code(s): 80299 Ref range: Therapeutic Range: 10-50 µg.mL - may be seen with common dosages. Toxic: Greater than 200 µg/mL Reported: 1-5 days IgA, Serum See: Immunoglobulin A (IgA), Serum IgD See: Immunoglobulin D (IgD) IgE See: Immunoglobulin E (IgE) S1 0 IGF Binding Protein-3 See: Insulin-Like Growth Factor Binding Protein-3 IGF-1 See: Insulin-Like Growth Factor 1 (IGF-1) IgG, CSF See: Immunoglobulin G (IgG), CSF IgG, Serum See: Immunglobulin G (IgG), Serum IGH/BCL-1 FISH Study Order code: 82131 Preferred specimen: 10.0 mL whole blood, green (sodium heparin) top tube or 2.0 mL bone marrow aspirate in a green (sodium heparin) top tube. Minimum specimen: 5.0 mL whole blood or 1.0 mL bone marrow Notes: Specimen must be received in laboratory within 24 hours of collection. Transport specimen on cold packs but do not place cold packs in direct contact with specimen. Other acceptable: Tissue (lymph nodes, spleen) in tissue media; Fluids 2-3 mL (ascitic, CSF) in sterile tube; Malignant fluids 50-100 mL in collection pouch; Fine Needle Aspirate in tissue media 10 pieces preferred (minimum of 2 pieces-0.2 cm³ in aggregrate); Formalin-fixed and paraffin-embedded tissue. Unacceptable: Clotted or frozen specimens. Paraffin-embedded tissue that has been decalcified. Transport temp: Refrigerated Method: Fluorescence in situ Hybridization (FISH) Unit code: 821310 CPT Code(s): 88368 (x2) Ref range: By report Reported: Paraffin-embedded tissue 7-10 days; all other specimen types within 3 days. Test List 10-266 BBPL Directory of Services IGH/BCL2 Fusion See: Chromosome Analysis, FISH-Interphase IGH/CCND1 See: IGH/BCL-1 FISH Study IgM, CSF See: Immunoglobulin M (IgM), CSF IgM, Serum See: Immunoglobulin M (IgM), Serum IgVH Mutation Analysis by Sequencing Order code: 82312 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube or 3 mL bone marrow (EDTA). TIME SENSITIVE. Specimens must be received in laboratory within 24 hours of collection due to lability of RNA. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: This assay is designed for individuals with a confirmed diagnosis of CLL, and for these individuals testing will include sequencing. All other diagnoses will terminate after amplification and will not have the sequencing component. Testing includes pathologist's interpretation. Unacceptable: Serum or plasma. Specimens collected in preservatives other than EDTA. Frozen specimens. Clotted or severely hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Sequencing Unit code: 821312 CPT Code(s): 81263, G0452 Ref range: By report Reported: 12-14 days S1 0 IL-2 (Interleukin 2) See: Interleukin 2 by MAFD IL-5 (Interleukin 5) See: Interleukin 5 by MAFD IL-6 (Interleukin 6) See: Interleukin 6 by MAFD Imipramine and Desipramine Order code: 83490 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: For therapeutic monitoring, collect specimen immediately prior to next dose (minimum 12 hours after last dose). Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood. Separator tubes or gels. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 821350 CPT Code(s): 80160, 80174 Ref range: Therapeutic: Imipramine + Desipramine: 150-300 ng/mL Toxic: >500 ng/mL Reported: 1-5 days 10-267 Test List BBPL Directory of Services Immune Complex Detection by C1Q Binding, Serum or Plasma Order code: 81280 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Let stand on clot for 2 hours. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum, frozen. Notes: If ordered in conjunction with a Raji Cell Assay, draw two 6 mL plain red top tubes and submit two 1 mL frozen serum samples for testing. Separate specimens specimens must be submitted when multiple tests are ordered. Unacceptable: Nonfrozen samples. Repeated freeze/thaw cycles should be avoided. Transport temp: CRITICAL FROZEN Method: Enzyme-Linked Immunosorbent Assay Unit code: 805400 CPT Code(s): 86332 Ref range: Less than 4 µgE/mL is considered negative for circulating complement binding immune complexes. Reported: 1-8 days Immune Complex, Raji Cell Order code: 85050 Preferred specimen: 3.0 mL serum, red top tube or SST. Let stand for two hours, then remove serum from cells within one hour and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL serum Unacceptable: Non-frozen specimens. Transport temp: CRITICAL FROZEN Method: Flow Cytometry Unit code: 810000 CPT Code(s): 86332 Ref range: By report Reported: 2-9 days Immunofixation Electrophoresis, CSF Order code: 1560 Preferred specimen: 5.0 mL CSF in a transport tube. Minimum specimen: 2.5 mL CSF Transport temp: Refrigerated S1 0 Method: Immunofixation Unit code: 113220 CPT Code(s): 84157, 84166, 86335 Ref range: Interpretive, see laboratory report Reported: 1-3 days Immunofixation Electrophoresis, Serum Order code: 1555 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Transport temp: Refrigerated Method: Immunofixation/Colorimetry Unit code: 113203 CPT Code(s): 84155, 84165, 86334 Ref range: Interpretive, see report Reported: 1-3 days Immunofixation Electrophoresis, Urine Order code: 1565 Preferred specimen: 25.0 mL urine aliquot from a well mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. Do not add preservatives or transport in urine preservative tubes. Record the total volume and hours of collection on both the specimen container and the test request form. Minimum specimen: 5.0 mL urine aliquot Unacceptable: Urines with preservative. Transport temp: Refrigerated Method: Immunofixation Unit code: 113240 CPT Code(s): 84156, 84166, 86335 Ref range: By report Reported: 1-3 days Test List 10-268 BBPL Directory of Services Immunoglobulin A (IgA), Serum Order code: 1415 Preferred specimen: 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens Transport temp: Refrigerated Method: Nephelometry Unit code: 112580 CPT Code(s): 82784 Ref range: Adult: 68-378 mg/dL Reported: 1-3 days Immunoglobulin D (IgD) Order code: 83460 Preferred specimen: 1.0 mL serum, SST or red top tube. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Notes: Plasma samples are not recommended. Unacceptable: Severely lipemic, contaminated, or hemolyzed samples. Transport temp: Refrigerated Method: Nephelometry Unit code: 821600 CPT Code(s): 82784 Ref range: Less than or equal to 15.3 mg/dL Reported: 1-4 days Immunoglobulin E (IgE) Order code: 1161 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.3 mL serum Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay S1 0 Unit code: 112610 CPT Code(s): 82785 Ref range: 0-364 days: 0-8 IU/mL 1-2 years: 0-12 IU/mL 3 years: 0-24 IU/mL 4-5 years: 0-50 IU/mL 6 years: 0-70 IU/mL 7-14 years: 0-120 IU/mL 15 years and older: 0-180 IU/mL Reported: 1-3 days Immunoglobulin G (IgG) Subclasses (1,2,3,4) Order code: 83480 Preferred specimen: 2.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.45 mL serum or plasma. Other acceptable: 2.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP. Transport temp: Refrigerated Method: Nephelometry Unit code: 821300 CPT Code(s): 82787 (x4) Ref range: By report Reported: 1-3 days Immunoglobulin G (IgG), CSF Order code: 1410 Preferred specimen: 1.0 mL CSF Minimum specimen: 0.5 mL CSF Transport temp: Refrigerated Method: Nephelometry Unit code: 112560 CPT Code(s): 82784 Ref range: 0.00-5.86 mg/dL Reported: 1-2 days 10-269 Test List BBPL Directory of Services Immunoglobulin G (IgG), Serum Order code: 1405 Preferred specimen: 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens Transport temp: Refrigerated Method: Nephelometry Unit code: 112550 CPT Code(s): 82784 Ref range: Adult: 694-1618 mg/dL Reported: 1-3 days Immunoglobulin M (IgM), CSF Order code: 82163 Preferred specimen: 1.0 mL CSF. Centrifuge and separate to remove cellular material. Transfer CSF to a plastic transport tube. Minimum specimen: 0.4 mL CSF Unacceptable: Grossly bloody or hemolyzed specimens. Transport temp: Refrigerated Method: Nephelometry Unit code: 821663 CPT Code(s): 82784 Ref range: 0-0.7 mg/dL Reported: Within 24 hours Immunoglobulin M (IgM), Serum Order code: 1425 Preferred specimen: 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens Transport temp: Refrigerated Method: Nephelometry Unit code: 112600 S1 0 CPT Code(s): 82784 Ref range: Adult: 60-263 mg/dL Reported: 1-3 days Immunoglobulin Panel (IgG, IgA, IgM), Serum Order code: 1404 Preferred specimen: 2.0 mL serum, SST or red top tube Minimum specimen: 1.0 mL serum Unacceptable: Extremely lipemic specimens Transport temp: Refrigerated Method: Nephelometry Unit code: 112500 CPT Code(s): 82784 (x3) Ref range: See individual tests. Reported: 1-2 days Immunoglobulins IgG, IgA, IgM, IgE, Serum Order code: 1412 Preferred specimen: 2.5 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.5 mL serum Notes: Test includes: Immunoglobulin G (IgG), Serum Immunoglobulin A (IgA), Serum Immunoglobulin M (IgM), Serum Immunoglobulin E (IgE) Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay/Nephelometry Unit code: 112505 CPT Code(s): 82784 (x3), 82785 Ref range: See individual tests Reported: 1-3 days Test List 10-270 BBPL Directory of Services Immunoglobulins, CSF Quantitative Order code: 81906 Preferred specimen: 1.0 mL CSF. Centrifuge and separate to remove cellular material. Transfer to a plastic transport tube. Minimum specimen: 0.6 mL CSF Unacceptable: Grossly bloody or hemolyzed specimens. Transport temp: Refrigerated Method: Quantitative Nephelometry Unit code: 821660 CPT Code(s): 82784 (x3) Ref range: Immunoglobulin A, CSF: 0-0.7 mg/dL Immunoglobulin G, CSF: 0-6.0 mg/dL Immunoglobulin M, CSF: 0-0.7 mg/dL Reported: 1-5 days Immunophenotyping-Cell Lineage See: Leukemia Immunophenotyping by Flow Cytometry, Acute Leukemia/Cell Lineage Immunophenotyping-Lymphoid See: Lymphoma Immunophenotyping by Flow Cytometry Inderal, Serum See: Propranolol India Ink Prep See: Fungal Smear Only Indirect Coombs S1 0 See: Antibody Screen Infectious Mononucleosis See: Mono Test, Heterophile Screen Mono, Heterophile Screen Reflex Inflammatory Bowel Disease Profile Order code: 82171 Preferred specimen: 1.5 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection. Minimum specimen: 0.6 mL serum Notes: Test includes: Saccharomyces cerevisiae Antibody, IgG Saccharomyces cerevisiae Antibody, IgA P-ANCA Unacceptable: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody Unit code: 821710 CPT Code(s): 86255, 86671 (x2) Ref range: Saccharomyces cerevisiae Antibody, IgG: 20.0 Units or less: Negative 20.1 to 24.9 Units: Equivocal 25.0 Units or greater: Positive Saccharomyces cerevisiae Antibody, IgA: 20.0 Units or less: Negative 20.1 to 24.9 Units: Equivocal 25.0 Units or greater: Positive Anti-Neutrophil Cytoplasmic Antibody, Atypical Pattern: < 1:20: Not significant Reported: 1-4 days 10-271 Test List BBPL Directory of Services Infliximab (IFX) Concentration + IFX Antibody Order code: 81726 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells within 45 minutes of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL serum Transport temp: Frozen Method: Electrochemiluminescence Immunoassay Unit code: 821726 CPT Code(s): 80299, 82397 Ref range: By report Reported: 3-12 days Influenza A & B Virus Antibodies, IgG & IgM Order code: 83617 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.05 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Unacceptable: Plasma specimens. Hemolyzed, lipemic, icteric, turbid, bacterially contaminated or heat-inactivated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 822150 CPT Code(s): 86710 (x4) Ref range: 0.89 IV or less: Negative 0.90-1.10 IV: Equivocal 1.11 IV or greater: Positive Reported: 1-6 days Influenza Antigen Screen A & B Order code: 3215 Preferred specimen: Collect nasal swab, aspirate, wash or throat swab. Place swab in a culturette container or in M6 viral transport media. Place nasal aspirate or wash in a sterile screw cap container. Other acceptable: Swab specimen in M4, M4RT, or M5 viral transport media. S1 0 Unacceptable: Dry swab not in culturette or viral transport media. Transport temp: Refrigerated Method: Immunochromatographic assay Unit code: 402150 CPT Code(s): 87400 (x2) Ref range: Negative Reported: Within 24 hours Influenza Virus RNA, Qualitative Real-Time PCR Order code: 39009 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Notes: Test includes: Influenza A, Influenza A Subtype H1 and H3, Influenza B. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction Unit code: 539009 CPT Code(s): 87502, 87503 (x3) Ref range: Negative Reported: 1-2 days Test List 10-272 BBPL Directory of Services Inherited Thrombophilia Mutation Profile Order code: 94554 Preferred specimen: 5.0 mL whole blood collected in lavender (EDTA), light blue (sodium citrate), or yellow (ACD Solution A or B) top tube. Separate specimens should be submitted when multiple tests are ordered. Minimum specimen: 3.0 mL whole blood Notes: Test includes: Factor V Leiden Mutation Prothrombin Gene Mutation MTHFR Gene Mutation Other acceptable: Liquid Based PAP Media. Unacceptable: Heparin anticoagulant, severely hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 94554 CPT Code(s): 81240, 81241, 81291 Ref range: By report Reported: 3-7 days Inhibin-A (Dimer) Order code: 82224 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Plasma and severely lipemic or hemolyzed specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 822240 CPT Code(s): 86336 Ref range: Normal Cycling Females: Early Follicular Phase (-14 to -10): 1.8-17.3 pg/mL Mid Follicular Phase (-9 to -4): 3.5-31.7 pg/mL Late Follicular Phase (-3 to -1): 9.8-90.3 pg/mL Mid Cycle (Day 0): 16.9-91.8 pg/mL Early Luteal (1 to 3): 16.1-97.5 pg/mL Mid Luteal (4 to 11 ): 3.9-87.7 pg/mL Late Luteal (12 to 14): 2.7-47.1 pg/mL S1 0 IVF-Peak Levels: 354.2-1690.0 pg/mL PCOS-Ovulatory: 5.7-16.0 pg/mL Postmenopausal: less than 6.9 pg/mL Normal Males: less than 2.1 pg/mL Reported: 1-2 days Inhibin-B Order code: 82041 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.2 mL serum Unacceptable: Hemolyzed, lipemic or room temperature specimens. Transport temp: Frozen Method: Enzyme-Linked Immunosorbent Assay Unit code: 822241 CPT Code(s): 83520 Ref range: By report Reported: 1-8 days Inorganic Phosphate, Serum See: Phosphate, Inorganic, Serum Insirect Coombs 10-273 Test List BBPL Directory of Services Insulin Antibodies Order code: 83640 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.1 mL serum Unacceptable: Plasma, hemolyzed or lipemic specimens. Transport temp: Frozen Method: Radioimmunoassay Unit code: 822300 CPT Code(s): 86337 Ref range: 0.0-0.4 Kronus Units/mL This assay quantitatively measures human serum autoantibodies to endogenous insulin or antibodies to exogenous insulin. A value of greater than 0.4 Kronus Units/mL is considered positive for Insulin Antibody. Note: Kronus Units are arbitrary. Kronus Units = U/mL Reported: 2-10 days Insulin, Free & Total Order code: 82305 Preferred specimen: 2.0 mL serum, SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.1 mL serum or plasma. Notes: Fasting specimen is preferred. Other acceptable: 2.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Unacceptable: Hemolyzed specimens. Heparin or sodium fluoride/potassium oxalate plasma. Transport temp: Frozen Method: Quantitative Ultrafiltration/Quantitative Chemiluminescent Immunoassay Unit code: 822305 CPT Code(s): 83525, 83527 Ref range: Insulin, Free: 3-19 uIU/mL Insulin, Total: 3-19 uIU/mL Reported: 2-3 days Insulin-1 Specimen Order code: 1346 S1 0 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Record time drawn on both the specimen and the test request form. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 104135 CPT Code(s): 83525 Ref range: By report Reported: Within 24 hours Insulin-2 Specimens Order code: 1342 Preferred specimen: 1.0 mL serum (per timed specimen), red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Record time drawn on each specimen and the test request form. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 104136 CPT Code(s): 83525 (x2) Ref range: By report Reported: Within 24 hours Insulin-3 Specimens Order code: 1343 Preferred specimen: 1.0 mL serum (per timed specimen), red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Record time drawn on each specimen and the test request form. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 104137 CPT Code(s): 83525 (x3) Ref range: By report Reported: Within 24 hours Test List 10-274 BBPL Directory of Services Insulin-4 Specimens Order code: 1344 Preferred specimen: 1.0 mL serum (per timed specimen), red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Record time drawn on each specimen and the test request form. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 104138 CPT Code(s): 83525 (x4) Ref range: By report Reported: Within 24 hours Insulin-5 Specimens Order code: 1345 Preferred specimen: 1.0 mL serum (per timed specimen), red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Record time drawn on each specimen and the test request form. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 104139 CPT Code(s): 83525 (x5) Ref range: By report Reported: Within 24 hours Insulin-6 Specimens Order code: 1347 Preferred specimen: 1.0 mL serum (per timed specimen), red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Record time drawn on each specimen and the test request form. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 104140 S1 0 CPT Code(s): 83525 (x6) Ref range: By report Reported: Within 24 hours Insulin-7 Specimens Order code: 1348 Preferred specimen: 1.0 mL serum (per timed specimen), red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Record time drawn on each specimen and the test request form. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 104141 CPT Code(s): 83525 (x7) Ref range: By report Reported: Within 24 hours Insulin-Like Growth Factor 1 (IGF-1) Order code: 85450 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.2 mL serum Unacceptable: Plasma specimens Transport temp: Refrigerated Method: Immunochemiluminometric Assay Unit code: 837800 CPT Code(s): 84305 Ref range: By report Reported: 1-3 days 10-275 Test List BBPL Directory of Services Insulin-Like Growth Factor Binding Protein-3 Order code: 82124 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Transport temp: Refrigerated Method: Immunochemiluminometric Assay (ICMA) Unit code: 821240 CPT Code(s): 82397 Ref range: By report Reported: 2-5 days Interferon Beta Neutralizing Antibody with Reflex to Titer Order code: 82809 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Collect specimens before Interferon beta treatment, or more than 48 hours following the most recent dose. Patient should not be on steroid therapy in excess of 10 mg prednisolone (or equivalent) daily. High endogenous levels of Interferon beta, alpha, or gamma may interfere with this assay. Minimum specimen: 0.3 mL serum Notes: If Interferon Beta Neutralizing Antibody screen result is positive, then Interferon Beta Neutralizing Antibody titer will be added at an additional charge. Unacceptable: Hemolyzed, icteric, lipemic, or contaminated specimens. Transport temp: Refrigerated Method: Cell Culture/Chemiluminescent Immunoassay Unit code: 828095 CPT Code(s): 86352 Ref range: Interferon Beta Screen: Negative Interferon Beta Titer: Less than 20: Negative 20 to 99: Moderate levels of neutralizing antibodies present 100 or greater: High levels of neutralizing antibodies present Reported: 1-15 days Interleukin 2 by MAFD Order code: 83315 S1 0 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.3 mL serum or plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 1.0 mL plasma, green (lithium heparin) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Unacceptable: Heat-inactivated, refrigerated, or contaminated specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Multiplex Bead Assay Unit code: 822315 CPT Code(s): 83520 Ref range: 12 pg/mL or less Note: Lower limit of detection is 5 pg/mL. Reported: 1-4 days Interleukin 28B (IL28B)-Associated Variants, 2 SNPs Order code: 82132 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A or B) top tube. Minimum specimen: 1.0 mL whole blood Notes: Please submit Patient History for Molecular Genetics and test request form along with specimen. Variants Tested: SNP rs12979860 C/T and SNP rs8099917 T/G. Transport temp: Refrigerated Method: Qualitative Polymerase Chain Reaction/Qualitative Fluorescence Monitoring Unit code: 821320 CPT Code(s): 81479 Ref range: By report Reported: 7-10 days Test List 10-276 BBPL Directory of Services Interleukin 5 by MAFD Order code: 82320 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.3 mL serum or plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 1.0 mL plasma, green (lithium heparin) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Unacceptable: Heat-inactivated, refrigerated or contaminated specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Multiplex Bead Assay Unit code: 822320 CPT Code(s): 83520 Ref range: 5 pg/mL or less Note: Lower limit of detection is 5 pg/mL Reported: 1-4 days Interleukin 6 by MAFD Order code: 82322 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.3 mL serum or plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 1.0 mL plasma, green (lithium heparin) top tube. Remove plasma from cells ASAP, transfer to a plastic transport tube and freeze. Unacceptable: Refrigerated specimens. Contaminated or heat-inactivated specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Multiplex Bead Assay Unit code: 822322 CPT Code(s): 83520 Ref range: 5 pg/mL or less Note: Lower limit of detection is 5 pg/mL. Reported: 1-4 days Intrinsic Factor Blocking Antibody, Serum S1 0 Order code: 83650 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.15 mL serum Unacceptable: Grossly hemolyzed or severely lipemic specimens. Transport temp: Frozen Method: Enzyme-Linked Immunosorbent Assay Unit code: 809400 CPT Code(s): 86340 Ref range: Negative Reported: 1-3 days Iodide, Serum or Plasma Order code: 82245 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Ion Chromatography Unit code: 822450 CPT Code(s): 82491 Ref range: By report Reported: Within 10 days 10-277 Test List BBPL Directory of Services Iodine, Serum Order code: 82425 Preferred specimen: 2.0 mL serum, royal blue (no additive) top tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a Trace Element-Free transport tube. Minimum specimen: 0.5 mL serum Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications for 48 hours prior to sample draw (upon the advice of their physician). In addition, the administration of iodine-based contrast media and drugs containing iodine may yield elevated results. During venipuncture, do not use disinfectants (such as Betadine) that contain iodine. This test reports total iodine from all iodine-containing species present in the specimen and is recommended for determination of iodine excess and monitoring iodine overload in patients administered iodine-containing medications. This test does not determine the chemical form (species) of the iodine present. Unacceptable: Plasma. Specimens not received in Trace Element Free transport tubes. Separator tubes and specimens that are not separated from the clot within 6 hours. Serum collected within 48 hours after administration of a gadolinium (Gd) or iodine (I) containing contrast media (may occur with MRI studies). Transport temp: Refrigerated Method: Quantitative Inductively Coupled Plasma-Mass Spectrometry Unit code: 822455 CPT Code(s): 83018 Ref range: 40-92 µg/L Values greater than 250 µg/L may indicate iodine overload. Reported: 1-5 days Ionized Calcium See: Calcium, Ionized Ionized Magnesium See: Magnesium, Ionized, Serum Irinotecan Toxiicity See: UDP Glucuronosyltransferase 1A1 (UGT1A1) Genotyping Iron and Iron Binding Capacity Order code: 1330 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Spectrophotometry/Calculation Unit code: 103140 CPT Code(s): 83540, 83550 Ref range: Iron: 40-150 mcg/dL TIBC: 240-450 mcg/dL % Saturation: 15-55% Reported: Within 24 hours Iron, 24-Hour Urine Order code: 83690 Preferred specimen: 10.0 mL urine aliquot from a well-mixed 24-hour urine collection. Collect in a clean plastic container with no metal cap(s) or glued insert(s) and refrigerate during collection. No preservative is needed. Specimen must be refrigerated within 4 hours of completion of 24-hour collection. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If gadolinium or iodine containing contrast media has been administered, a specimen should not be collected for 48 hours. Unacceptable: Room temperature specimens. Transport temp: Refrigerated Method: Inductively Coupled Plasma-Optical Emission Spectrometry Unit code: 822550 CPT Code(s): 83540 Ref range: By report Reported: Varies Test List 10-278 S1 0 BBPL Directory of Services Iron, Liver Order code: 83680 Preferred specimen: At least 1 cm long specimen of liver tissue (obtained with an 18 gauge needle). Tissue can be fresh, paraffin-embedded, formalinfixed, or dried. Specimens should be stored and transported in an metal-free container such as a royal blue (no additive) top tube. Minimum specimen: Specimen should not be less than 0.25 mg (dry weight). Notes: Age is required on test request form in order to calculate iron index. Unacceptable: Specimens less than 0.25 mg (dry weight). Specimens stored or shipped in saline. Transport temp: Refrigerated Method: Quantitative Inductively Coupled Plasma/Mass Spectrometry Unit code: 822500 CPT Code(s): 83540 Ref range: Male: Hepatic Iron Content (HIC): 200-2,000 µg/g of tissue; Hepatic Iron Index (HII): less than 1.0 Female: Hepatic Iron Content (HIC): 200-1,600 µg/g of tissue; Hepatic Iron Index (HII): less than 1.0 Reported: 2-6 days Iron, Random Urine Order code: 82254 Preferred specimen: 2.0 mL random urine in a clean plastic urine container. Minimum specimen: 0.5 mL urine Notes: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium or iodine containing contrast media has been administered, a specimen should not be collected for 4 days. The preferred specimen for assessing urinary iron excretion is a 24-hour urine specimen. Transport temp: Refrigerated Method: Quantitative Inductively Coupled Plasma/Emission Spectrometry Unit code: 822549 CPT Code(s): 83540 Ref range: By report Reported: Varies Iron, Serum S1 0 Order code: 1065 Preferred specimen: 1.0 mL serum, red top tube or SST tube Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Colorimetric Unit code: 101690 CPT Code(s): 83540 Ref range: 40-150 mcg/dL Reported: Within 24 hours Islet Cell Antibody Order code: 80890 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Plasma, severely lipemic, contaminated, or hemolyzed samples. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 822600 CPT Code(s): 86341 Ref range: Negative: <1:1 Reported: 3-9 days 10-279 Test List BBPL Directory of Services Isopropanol (Includes Acetone) Order code: 80380 Preferred specimen: 3.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a tightly-capped plastic transport tube to minimize alcohol loss. Minimum specimen: 0.5 mL serum or plasma Notes: For medical purposes only. Other acceptable: 3.0 mL plasma, gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection and transfer to a tightly-capped plastic transport tube. Sodium fluoride/potassium oxalate whole blood may be transported in the original container. Do not freeze whole blood. Transport temp: Refrigerated Method: Quantitative Gas Chromatography Unit code: 801650 CPT Code(s): 84600 Ref range: Isopropanol: No therapeutic range - Limit of detection 5 mg/dL Toxic: > 50 mg/dL Acetone, Quantitative: No therapeutic range - Limit of detection 5 mg/dL Toxic: > 100 mg/dL Toxic concentrations may cause nausea, dizziness, central nervous system depression and coma. Reported: 1-2 days Isoptin See: Verapamil Isospora Stain See: Cryptosporidium, Isospora, and Cyclospora Stain Isotretinoin, Quantitative Order code: 82266 Preferred specimen: 3.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 1.2 mL serum or plasma. Notes: Remove serum or plasma from cells ASAP and transfer to a plastic amber transport tube. Protect from light during collection, storage, and shipment. Other acceptable: 3.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tubes or gels or specimens not protected from light. Transport temp: Room temperature Method: High Performance Liquid Chromatography Unit code: 822660 CPT Code(s): 82491 Ref range: By report Reported: Within 10 days Itraconazole, Quantitation by LC-MS/MS Order code: 82267 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.6 mL serum or plasma Notes: Specimens for trough levels should be obtained just before or within 15 minutes of next dose. Specimens for peak levels should be obtained within 15-30 minutes after the end of I.V. infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Unacceptable: Separator tubes or gels. Hemolyzed or lipemic specimens. Transport temp: Frozen Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 822670 CPT Code(s): 80299 Ref range: Itraconazole (trough) - Localized Infection: Greater than 0.5 µg/mL Itraconazole (trough) - Systemic Infection: Greater than 1.0 µg/mL Hydroxyitraconazole: No therapeutic range established Total concentrations for itraconazole and hydroxyitraconazole should not exceed 10 µg/mL. Adverse effects may include nausea, vomiting and rash. Reported: 1-6 days Test List 10-280 S1 0 BBPL Directory of Services JAK2 (V617F) Mutation by PCR Order code: 50902 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD Solution A) top tube. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Testing includes pathologist's interpretation. Other acceptable: 3.0 mL bone marrow in lavender (EDTA) top tube. Unacceptable: Frozen specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 550902 CPT Code(s): 81270, G0452 Ref range: Not detected Reported: 2-7 days JAK2 Exon 12 Mutation Analysis by PCR Order code: 82272 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or 3.0 mL bone marrow (EDTA). Do not freeze. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Testing includes pathologist's interpretation. Unacceptable: Serum, frozen specimens, clotted or grossly hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 822702 CPT Code(s): 81403, G0452 Ref range: By report Reported: 7-10 days JC Virus by PCR Order code: 87100 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube or 1.0 mL serum, SST. Remove plasma or serum from cells, transfer to a plastic transport tube and freeze. S1 0 Minimum specimen: 0.5 mL Other acceptable: 1.0 mL CSF or urine in a sterile container, frozen. Unacceptable: Heparinzed specimens. Transport temp: Frozen Method: Polymerase Chain Reaction Unit code: 822710 CPT Code(s): 86711 Ref range: By report Reported: 3-5 days JCV Antibody with Reflex to Inhibition Assay Order code: 82211 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.25 mL serum or plasma Notes: If the JCV Antibody result is Indeterminate, JCV Antibody Inhibition Assay will be performed at an additional charge. Other acceptable: 0.5 mL plasma, lavender (EDTA) top tube. Transport temp: Refrigerated Method: Immunoassay Unit code: 822711 Ref range: Negative Reported: Within 14 days JO-1 Antibody, IgG Order code: 5215 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Plasma, severely hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 350121 CPT Code(s): 86235 Ref range: <16 EU/mL Negative 16-20 EU/mL Inconclusive >20 EU/mL Positive Reported: 1-3 days 10-281 Test List BBPL Directory of Services Kappa/Lambda Free Light Chains, Quantitative See: Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum Free Kappa & Lambda Light Chains, Quantitative, Urine Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum Order code: 1513 Preferred specimen: 1.0 mL serum, SST or red top tube. Remove serum from cells immediately after clotting (within 30 minutes) and transfer to a plastic transport tube. Patient should be fasting for 8 hours to avoid lipemic sample interference. Minimum specimen: 0.5 mL serum Notes: Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy. Unacceptable: Hemolyzed, lipemic, or microbial contaminated specimens. Transport temp: Refrigerated Method: Immunoturbidimetric Unit code: 113500 CPT Code(s): 83883 (x2) Ref range: Kappa Free Light Chains: 3.30-19.40 mg/L Lambda Free Light Chains: 5.71-26.30 mg/L K/L Free Light Chain Ratio: 0.26-1.65 Reported: 1-4 days Ketosteroids, Fractionated (17) See: 17-Ketosteriods, Fractionated, Urine Ketosteroids, Total (17) See: 17-Ketosteroids, Total, Urine Kidney Stone Analysis See: Stone (Calculi) Analysis Kidney Stone Risk Panel, Urine Order code: 83833 Preferred specimen: Urine from a well-mixed 24-hour urine collection. Refrigerate urine during collection period. Use Calculi Risk/Supersaturation Urine collection kit for preserving the specimen for delivery to the laboratory. Kits are available through BBPL Client Services. Follow the instructions provided in the kit for collecting, processing, and transporting the urine specimen. Do not exceed 4 mL in tubes. Freeze the urine aliquot tubes after processing and deliver to the laboratory as soon as possible. Record the total volume and hours of collection on the test request form. Minimum specimen: 4 mL urine for each aliquot. Other acceptable: Collect 24-hour urine and submit entire urine to the laboratory within 12 hours after collection is complete. Refrigerate during collection and transport refrigerated to the laboratory. Transport temp: Frozen aliquot tubes Method: Quantitative Spectrophotometry/Quantitative Enzymatic Unit code: 838330 CPT Code(s): 82340, 82507, 83945, 84560 Ref range: By report Reported: 2-6 days KIT Mutations in AML by Fragment Analysis and Sequencing Order code: 82955 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube or 3.0 mL bone marrow (EDTA). Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Testing includes pathologist's interpretation. Unacceptable: Serum or plasma. Frozen or clotted specimens. Specimens collected in anticoagulants other than EDTA. Severely hemoloyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Fragment Analysis/Sequencing Unit code: 822955 CPT Code(s): 81404, G0452 Ref range: By report Reported: 12-14 days Kleihauer-Betke See: Fetal Maternal Hemorrhage, Blood Test List 10-282 S1 0 BBPL Directory of Services KOH Prep See: Fungal Smear Only Fungal Stain KOH, Skin, Hair, Nails Trichomonas & KOH Prep, Genital Kolpoxide See: Librium & Nordiazepam KRAS Mutation Analysis Order code: 32210 Preferred specimen: Formalin-fixed, paraffin-embedded (FFPE) tissue block containing greater than 25% tumor or five precut, unstained slides from paraffin block in 7-micron thick sections, and one H&E reference slide. Notes: Testing includes pathologist's interpretation. Unacceptable: Tumor block containing insufficient tumor tissue. Transport temp: Room temperature Method: Real-Time Polymerase Chain Reaction Unit code: 532210 CPT Code(s): 81275, 88381, G0452 Ref range: By report Reported: Within 7 days L Carnitine, Free See: Carnitine, Free L Carnitine, Total See: Carnitine, Total S1 0 L-Carnitine Free See: Carnitine, Free L-Carnitine Total See: Carnitine, Total L/S Ratio Order code: 84000 Preferred specimen: 10.0 mL amniotic fluid. Protect from light and transport frozen. Minimum specimen: 5.0 mL amniotic fluid Notes: Fetal Lung Maturity may be used instead for non-diabetic patients. Transport temp: Frozen Unit code: 823050 CPT Code(s): 83661 Ref range: By report Reported: Within 24 hours Lacosamide (Vimpat) Order code: 82307 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: High Performance Liquid Chromatography/Tandem Mass Spectrometry Unit code: 823070 CPT Code(s): 80299 Ref range: Therapeutic Range: Not well established. Suggested range 5.0-10.0 µg/mL Dose-related range (values at dosages of 200-600 mg/day): 2.5-18.0 µg/mL Toxic Level: Not well established Reported: 1-4 days 10-283 Test List BBPL Directory of Services Lactate Dehydrogenase (LD) Isoenzymes Order code: 82309 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow serum to clot completely at room temperature. Remove serum from cells ASAP and transfer to a plastic transport tube. Keep at room temperature. Minimum specimen: 0.6 mL serum Notes: Do not refrigerate or freeze. Hemolyzed specimens and serum which have not been separated from cells show elevated LD-1 and LD-2. LD-3, LD-4 and LD-5 are labile at low temperatures and are erroneously low in specimens that have been refrigerated or frozen. Unacceptable: Plasma, frozen, refrigerated, or hemolyzed specimens. Transport temp: Room temperature Method: Enzymatic/Electrophoresis Unit code: 823095 CPT Code(s): 83615, 83625 Ref range: LD-1: 14-27% LD-2: 29-42% LD-3: 18-30% LD-4: 8-15% LD-5: 6-23% Lactate Dehydrogenase, Total: 0 up to 30 days: 200-465 U/L 1-17 months: 200-450 U/L 18 months-10 years: 165-430 U/L 11-16 years: 127-287 U/L 17 years and older: 105-230 U/L Reported: 1-2 days Lactate Dehydrogenase, Fluid Order code: 1531 Preferred specimen: 1.0 mL body fluid in a plastic transport tube. Minimum specimen: 0.5 mL fluid Notes: Indicate source on test requisition. Transport temp: Refrigerated Method: Enzymatic Unit code: 103180 CPT Code(s): 83615 Ref range: None established S1 0 Reported: Within 24 hours Lactate Dehydrogenase, Total, Serum Order code: 1115 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Enzymatic Unit code: 101830 CPT Code(s): 83615 Ref range: 60-250 U/L Reported: Within 24 hours Lactate, Plasma See: Lactic Acid, Plasma Lactic Acid, Plasma Order code: 83720 Preferred specimen: 1.0 mL plasma, gray (sodium fluoride/potassium oxalate) top tube. Avoid hand-clenching and, if possible, avoid use of tourniquet. If tourniquet is used, release before blood is drawn and wait about 1 minute before drawing blood. Place gray top tube on ice immediately after venipuncture. Remove the plasma from cells immediately after collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL plasma Notes: Patient should be fasting and at complete rest (should not exercise). Patient should not be on any intravenous infusion that would affect the acid-base balance. Unacceptable: EDTA, citrate, or iodoacetate as anti-coagulants, marked hemolysis, slight or moderate turbidity, or serum specimens. Transport temp: Refrigerated Method: Lactate-pyruvate; Spectrophotometry Unit code: 823100 CPT Code(s): 83605 Ref range: 4.5-19.8 mg/dL Reported: Within 1-3 days Test List 10-284 BBPL Directory of Services Lactoferrin, Fecal Order code: 82110 Preferred specimen: 5 gm stool preserved in Cary-Blair media. Minimum specimen: 1 gm stool Unacceptable: Specimen preservatives other than Cary-Blair. Transport temp: Refrigerated Method: Qualitative Enzyme-Linked Immunosorbent Assay Unit code: 823110 CPT Code(s): 83630 Ref range: Negative A positive result is indicative of the presence of lactoferrin, a marker for fecal leukocytes. A negative result does not exclude the presence of intestinal inflammation. Reported: 1-2 days Lactose Tolerance Test Order code: 15085 Preferred specimen: 1.0 mL serum, SST, for each timed specimen. Label each specimen with patient name and time interval. Special Instructions: Draw fasting specimen prior to lactose administration. Fasting patient should be given 100 g lactose in 200-300 mL water consumed in 5-10 minutes. Note: if severe lactose deficiency is suspected, the dose should be lowered. After lactose administration, collect subsequent specimens 30 minutes, 1 hour, 2 hours, and 3 hours later. Minimum specimen: 0.5 mL serum for each timed specimen. Notes: Lactose to be supplied by the patient's physician or a pharmacy, not provided by the laboratory. Test includes: Fasting specimen, 1/2 hour, 1-hour, 2-hour, and 3-hour specimens. Transport temp: Refrigerated Method: Hexokinase Unit code: 102300 CPT Code(s): 82951, 82952 (x2) Reported: Within 24 hours Lambda Free Light Chains, Serum See: Kappa/Lambda Quantitative Free Light Chains, Serum S1 0 Lambert-Eaton Myasthenic Syndrome (LEMS) Antibodies See: Myasthenia Gravis/Lambert-Eaton Syndrome Evaluation Lamotrigine (Lamictal) Order code: 1145 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Draw trough specimen immediately prior to or within 1 hour of next dose at steady state. Indicate collection time on both the transport tube and test request form. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 110045 CPT Code(s): 80175 Ref range: 3.0-15.0 µg/mL Reported: Within 24 hours Lanatoxin See: Digitoxin Lanoxin See: Digoxin LAP Stain See: Leukocyte Alkaline Phosphatase Stain LAP, Serum See: Leucine Aminopeptidase 10-285 Test List BBPL Directory of Services Laroxyl See: Amitriptyline & Nortriptyline LATS (Long-acting Thyroid Stimulator) See: Thyroid Stimulating Immunoglobulin LD See: Lactate Dehydrogenase, Total, Serum Lactate Dehydrogenase (LD) Isoenzymes Lactate Dehydrogenase, Fluid LD Isoenzymes See: Lactate Dehydrogenase (LD) Isoenzymes LDH See: Lactate Dehydrogenase, Total, Serum Lactate Dehydrogenase (LD) Isoenzymes Lactate Dehydrogenase, Fluid LDH Fluid See: Lactate Dehydrogenase, Fluid LDH Isoenzymes See: Lactate Dehydrogenase (LD) Isoenzymes S1 0 LDL Cholesterol, Calculation, Serum See: Lipid Profile LDL Cholesterol, Direct, Serum Order code: 82315 Preferred specimen: 1.0 mL serum, SST. Allow serum to clot completely at room temperature before centrifuging. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Quantitative Detergent Solubilization/Enzymatic Unit code: 823150 CPT Code(s): 83721 Ref range: Age 0-19 years: Desirable 109 mg/dL or less Borderline 110-129 mg/dL Higher Risk 130 mg/dL or greater Age 20 years and older: Desirable 129 mg/dL or less (99 mg/dL or less if patient has CHD) Borderline 130-159 mg/dL Higher Risk 160 mg/dL or greater Reported: Within 24 hours Test List 10-286 BBPL Directory of Services LDL Subclasses Order code: 82311 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells ASAP or within 2 hours of collection. Minimum specimen: 0.2 mL serum or plasma Notes: Patient should be fasting for 12 hours prior to collection. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection. Unacceptable: Heparinized plasma. Specimens from patients receiving heparin. Transport temp: Refrigerated Method: Electrophoresis Unit code: 823151 CPT Code(s): 82465, 83701 Ref range: By report Reported: 1-8 days Lead, Blood Order code: 83800 Preferred specimen: 7.0 mL whole blood, royal blue (K EDTA or Na EDTA) or 3.0 mL whole blood, tan (K EDTA) top tube, in the original collection 2 2 tube at room temperature or refrigerated is also2acceptable. Minimum specimen: 0.5 mL whole blood Notes: This test is for venous collection only. Unacceptable: Heparin anticoagulant. Frozen specimens. Transport temp: Room temperature Method: Quantitative Inductively Coupled Plasma/Mass Spectrometry Unit code: 823650 CPT Code(s): 83655 Ref range: 0.0-4.9 µg/dL Reported: 1-2 days Lead, Fingerstick, Filter Paper S1 0 Order code: 82351 ® Preferred specimen: Collect according to the instructions provided on the MedTox Quik-Card filter paper for Pediatric Lead Test. Filter paper collection card is available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Great care must be taken to remove lead from the hands of the patient and collection personnel prior to collection and also prevent contamination of the filter paper by the environment. 1. Open the matchbook-style collection card and place on a clean, flat surface. Do not touch the filter paper or the inner shiny surface of the collection card. 2. Thoroughly wash patient's hands with soap and water. 3. Scrub tip of finger with an alcohol prep pad and air dry or wipe with sterile gauze. 4. Pierce the skin of the prepped finger with a lancet. Wipe off the first drop of blood with sterile gauze. 5. Allow a blood drop to accumulate and fall onto one of the circles on the sample card. Collect a second blood drop on the second circle in the same manner. Do not allow the finger to touch the paper. NOTE: The circles are provided as a guide for the approximate size and location of the blood spots. The sample is acceptable if the blood spots fall outside of the circles as long as they are of adequate size. Examine the reverse side of the filter paper to make sure blood has soaked through to the back. 6. Write the patient's name on the sample card. 7. Allow the blood spots to dry for 2 to 5 minutes, tuck in the top flap to create a "matchbook". Unacceptable: Quantity not sufficient or blood did not soak through to the back of filter paper. Samples received wet cannot be tested. Transport temp: Room temperature Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 823551 CPT Code(s): 83655 Ref range: Lead Reference Range: <5 µg/dL Lead Report Limit: 1 µg/dL Critical Value - High: 20 µg/dL Reported: 4-5 days 10-287 Test List BBPL Directory of Services Lead, Urine, Quantitative Order code: 83830 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Specimen must be collected in a plastic container and refrigerated during collection period. Submit specimen in two Trace Element-Free transport tubes. Do not add acid preservative. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 823750 CPT Code(s): 83655 Ref range: Lead, Urine 0-23 µg/L Lead, Urine (24-hour) 0-31 µg/d Reported: 1-3 days Lead, Whole Blood Capillary Order code: 83820 Preferred specimen: 0.5 mL whole blood, lavender (EDTA) Microtainer tube. Mix well (invert 10 times) to prevent clot formation. Minimum specimen: 0.3 mL whole blood Notes: This test should only be ordered for specimens obtained using skin puncture (capillary ) technique. Clean puncture site well with soap and water before collection procedure begins. Unacceptable: Heparin anticoagulant Transport temp: Room temperature Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 823600 CPT Code(s): 83655 Ref range: 0.0-4.9 µg/dL Reported: 1-3 days Leflunomide Metabolite Order code: 83766 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma Notes: Timing of specimen collection: Predose (trough). Obtain specimen 12-24 hours after last dose. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood. Potassium oxalate or separator tubes or gels. Transport temp: Refrigerated Method: High Performance Liquid Chromatography/Mass Spectrometry Unit code: 823766 CPT Code(s): 80299 Ref range: Therapeutic Range: Greater than 40 µg/mL Toxic Level: Not well established Reported: 1-6 days Legionella pneumophila Antibody (Types 1-6), IgG by IFA, Serum Order code: 83840 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Unacceptable: Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 824050 CPT Code(s): 86713 Ref range: <1:128 Negative - No significant level of Legionella pneumophila Type 1-6 IgG antibody detected. 1:128 Equivocal - Questionable presence of Legionella pneumophila Type 1-6 IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1:256 or greater Positive - Presence of Legionella pneumophila Type 1-6 IgG antibody detected, suggestive of current or past infection. Reported: 1-4 days Test List 10-288 S1 0 BBPL Directory of Services Legionella pneumophila Antigen, Urine Order code: 82377 Preferred specimen: 4.0 mL aliquot from a well-mixed random urine specimen. No preservative. Minimum specimen: 1.0 mL urine aliquot Notes: This assay detects Legionella pneumophila serogroup one (1) antigen. Unacceptable: Specimens in preservative. Transport temp: Refrigerated Method: Qualitative Enzyme-Linked Immunosorbent Assay Unit code: 823775 CPT Code(s): 87449 Ref range: Negative Reported: Within 24 hours Legionella pneumophila DFA Order code: 82391 Preferred specimen: Collect: Respiratory tract specimens (secretions, aspirates, BAL, tissue, fluids, sputum, abscess material) or pericardial fluid. Fluid: Transport prepared duplicate slides or 1.0 mL fluid in a sterile container. Tissue: Transfer tissue to a sterile container and place on gauze moistened with sterile non-bacteriostatic saline to prevent drying. Source of specimen is preferred. Notes: DFA is not recommended for diagnosing Legionella pneumophila-caused infections. For diagnosing Legionella pneumophilacaused infections, refer to Culture, Legionella Species (order code 83842). Unacceptable: Non-respiratory specimens. Specimens in preservative or viral transport medium. Transport temp: Frozen Method: Direct Fluorescent Antibody Stain Unit code: 823951 CPT Code(s): 87278 Ref range: Negative Reported: Within 24 hours Legionella Species by Qualitative PCR Order code: 82384 Preferred specimen: Collect respiratory specimen; sputum, tracheal aspirates, nasopharyngeal swab, pleural fluid, bronchoalveolar lavage (BAL), or bronchial brushings. Transport 2.0 mL fluid in sterile container or in viral transport media. Place swabs in viral transport media. Specimen source is required. S1 0 Minimum specimen: 0.5 mL fluid Notes: This test detects and speciates L. pneumophila. The nucleic acid from other Legionella species will be detected by this test but cannot be differentiated. Unacceptable: Dry swabs and nonsterile or leaking containers. Respiratory aspirates in collection containers with tubing. These containers tend to leak compromising the specimen. Transport temp: Frozen Method: Qualitative Polymerase Chain Reaction Unit code: 823840 CPT Code(s): 87541 Ref range: By report Reported: 1-2 days Legionella Species, Culture See: Culture, Legionella Species Leptin Order code: 82409 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.2 mL serum Notes: Patient should fast overnight prior to collection. Unacceptable: Icteric specimens or severely hemolyzed specimens. Non-fasting specimens. Transport temp: Frozen Method: Quantitative Chemiluminescent Assay Unit code: 824090 CPT Code(s): 83520 Ref range: 0-17 years: Not Established Adult Male: 0.5-12.5 ng/mL Adult Female: 0.5-15.2 ng/mL Reported: 1-5 days 10-289 Test List BBPL Directory of Services Leptospira Antibody, IgM by Dot Blot Order code: 82415 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum or plasma Notes: Remove serum or plasma from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Unacceptable: Severely lipemic, hemolyzed, heat-inactivated, or contaminated specimens. Any other body fluid. Transport temp: Refrigerated Method: Dot Blot Unit code: 824105 CPT Code(s): 86720 Ref range: Negative: No significant level of Leptospira IgM antibody detected. Equivocal: Questionable presence of Leptospira IgM antibody detected. Repeat testing in 10-14 days may be helpful. Positive: Presence of IgM antibody to Leptospira detected, suggestive of a current or recent infection. Reported: 1-5 days Leptospira Antibody, Serum Order code: 83860 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.05 mL serum Transport temp: Refrigerated Method: Indirect Hemagglutination Unit code: 824100 CPT Code(s): 86720 Ref range: < 1:50 Negative - No antibody detected. 1:50 Equivocal - Suggest repeat testing in two to three weeks. >= 1:100 Positive - Suggestive of current or recent leptospirosis. Reported: 1-4 days Leucine Aminopeptidase Order code: 83740 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow serum to clot completely at room temperature. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or light blue (sodium citrate) top tube. Remove plasma from cells ASAP. Transport temp: Refrigerated Method: Spectrophotometry Unit code: 824200 CPT Code(s): 83670 Ref range: Male: 1.1-3.4 U/mL Female: 1.2-3.0 U/mL Reported: 1-8 days Leukemia Immunophenotyping by Flow Cytometry, Acute Leukemia/Cell Lineage Order code: 35416 Preferred specimen: Whole Blood: 5.0 mL whole blood, lavender (EDTA) top tube and/or 1 yellow (ACD solution A) top tube. Bone Marrow: 2.0 mL bone marrow submitted in a green (sodium heparin) top tube. After specimen is well mixed with anticoagulant, add equal amount of RPMI to the tube and invert to mix. Label specimen as bone marrow. Tissue: Fresh tissue submitted in 10-15 mL RPMI. Specimens must be received within 48 hours of collection. Do not freeze specimens. Notes: Includes: CD45, CD13, CD14, CD7, CD3, CD20, CD19, CD15, CD10, CD33, CD34, HLA-DR, Kappa/Lambda light chains, and pathologist interpretation. May include other antibodies as indicated by initial findings. Requisition should include suspected diagnosis and any available patient history. Unacceptable: Fixed or frozen specimens. Transport temp: Refrigerated Method: Flow Cytometry Unit code: 535416 CPT Code(s): 88184, 88185 (x19) Ref range: By report Reported: 1-3 days Test List 10-290 S1 0 BBPL Directory of Services Leukocyte Alkaline Phosphatase Stain Order code: 2285 Preferred specimen: 7.0 mL whole blood, green (sodium or lithium heparin) top tube. Blood must be received in the lab the same day as drawn. Minimum specimen: 3.0 mL heparinized whole blood. Unacceptable: Specimens not received same day as drawn. Separator tubes or gels. Specimens collected in EDTA. Transport temp: Room temperature Method: Cytochemical stain Unit code: 201900 CPT Code(s): 85540 Ref range: Low: 0-13 Borderline: 14-23 Normal: 24-100 High: >100 Reported: 1-4 days Levetiracetam (Keppra) Order code: 1148 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Draw trough specimen immediately prior to or within 1 hour of next dose at steady state. Indicate collection time on both the transport tube and test request form. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 110048 CPT Code(s): 80177 Ref range: 6.0-46.0 µg/mL Reported: Within 24 hours Levodopa See: Sinemet S1 0 LH, Serum See: Luteinizing Hormone LH/FSH Panel Order code: 1288 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.6 mL serum Notes: Test includes Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111097 CPT Code(s): 83001, 83002 Ref range: Follicle Stimulating Hormone (FSH): Females: Follicular Phase: 2.5-10.2 mIU/mL Mid-Cycle Peak: 3.4-33.4 mIU/mL Luteal Phase: 1.5-9.1 mIU/mL Postmenopausal: 23.0-116.3 mIU/mL Pregnancy: <0.3 mIU/mL Male: 1.4-18.1 mIU/mL Luteinizing Hormone (LH): Females: Follicular Phase: 2.5-10.2 mIU/mL Mid-Cycle Peak: 3.4-33.4 mIU/mL Luteal Phase: 1.5-9.1 mIU/mL Postmenopausal: 23.0-116.3 mIU/mL Pregnancy: <0.3 mIU/mL Male: 1.4-18.1 mIU/mL Reported: Within 24 hours Librax See: Librium & Nordiazepam 10-291 Test List BBPL Directory of Services Librium & Nordiazepam Order code: 81540 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Do not draw in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Frozen Method: High Performance Liquid Chromatography/Gas Chromatography Unit code: 807350 CPT Code(s): 80154 (x2) Ref range: Dose-Related Range: Librium: 0.5-3.0 µg/mL - Dose (Adult): 5-100 mg Toxic: >5.0 µg/mL Nordiazepam: 0.1-1.5 µg/mL - Based on normal dosages. Toxic: >2.5 µg/mL Reported: 1-5 days Lidocaine Order code: 83880 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells immediately and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Draw specimens 12 hours after initiating therapy for arrhythmia prophylaxis, then every 24 hours thereafter. Other acceptable: 1.0 mL plasma, green (sodium heparin) top tube. Remove plasma from cells immediately and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Specimens collected in lavender (EDTA) or gray (sodium fluoride/potassium oxalate) top tubes. Transport temp: Refrigerated Method: Fluorescence Polarization Immunoassay Unit code: 824350 CPT Code(s): 80176 Ref range: 1.2-5.0 µg/mL Toxic: greater than 9.0 µg/mL S1 0 Reported: 1-2 days Lidocaine & Metabolite Order code: 82435 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 0.4 mL serum or plasma Notes: Test includes Lidocaine and Monoethylglycinexylidide. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Gas Chromatography Unit code: 824351 CPT Code(s): 80176 Ref range: By report Reported: 3-10 days Limbitrol See: Amitriptyline & Nortriptyline Lipase, Serum Order code: 1528 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Enzymatic Unit code: 103155 CPT Code(s): 83690 Ref range: 7-60 U/L Reported: Within 24 hours Test List 10-292 BBPL Directory of Services Lipid Associated Sialic Acid, (LASA), Serum Order code: 83930 Preferred specimen: 0.5 mL serum, SST. Allow serum to clot completely at room temperature. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.2 mL serum Notes: Samples lose up to 25% LASA in 24 hours if left at room temperature. Unacceptable: Non-frozen samples are not accepted. Transport temp: CRITICAL FROZEN Method: Spectrophotometry Unit code: 823200 CPT Code(s): 84275 Ref range: 0-20 mg/dL Reported: 1-8 days Lipid Profile Order code: 1003 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transport to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: Test includes: Cholesterol Cholesterol/HDL Triglycerides HDL LDL (Calculated) LDL/HDL Phenotype Transport temp: Refrigerated Method: See individual tests Unit code: 94005 CPT Code(s): 80061 Ref range: Adult ranges Cholesterol: <200 mg/dL Triglycerides: <150 mg/dL HDL: >=40 mg/dL LDL (Calculated): <130 mg/dL Reported: Within 24 hours S1 0 Lipids-Total, Stool, Quantitative See: Fecal Fat Quantitative Lipoprotein (a) Order code: 84572 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP (within 2 hours of collection) and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma. Notes: Intake of alcohol, aspirin, niacin, and estrogen supplements have the potential of causing a misrepresentation of true Lp(a) concentrations. Other acceptable: 0.5 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or light blue (sodium citrate) top tube. Remove plasma from cells ASAP (within 2 hours of collection) and transfer to a plastic transport tube. Unacceptable: Grossly hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Immunoturbidimetric Unit code: 824570 CPT Code(s): 83695 Ref range: <75 nmol/L Reported: 1-2 days Lipoprotein Electrophoresis Order code: 1580 Preferred specimen: 1.0 mL serum, SST or red top tube. DO NOT FREEZE. Minimum specimen: 0.5 mL serum Notes: Patient should be fasting for 12-15 hours. Unacceptable: Body fluids. Heparin or frozen specimens. Transport temp: Refrigerated Method: Qualitative Electrophoresis/Quantitative Enzymatic /Detergent Solubilization Unit code: 824578 CPT Code(s): 83700 Ref range: By report Reported: 1-8 days 10-293 Test List BBPL Directory of Services Lipoprotein-Associated Phospholipase A2 Order code: 82475 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow serum specimen to clot completely at room temperature. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 1.0 mL plasma, green (lithium or sodium heparin) or lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood or hemolyzed specimens. Transport temp: Refrigerated Method: Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 824575 CPT Code(s): 83698 Ref range: 0-234 ng/mL Reported: 1-4 days Lithium Order code: 1175 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Notes: Sampling time: Collect 8-12 hours after last dose. Other acceptable: 0.5 mL plasma, green (sodium heparin) top tube. Unacceptable: Plasma collected in lithium heparin tubes. Transport temp: Refrigerated Method: Colorimetric Unit code: 110050 CPT Code(s): 80178 Ref range: Initial: 1.0-1.5 mEq/L Maintenance: 0.5-1.0 mEq/L Potentially toxic: >3.0 mEq/L Reported: Within 24 hours Lithobid S1 0 See: Lithium Lithonate See: Lithium Liver Fibrosis, Chronic Viral Hepatitis (Echosens FibroMeter) Order code: 84579 Preferred specimen: 3.0 mL serum, gel-barrier tube and 1.0 mL platelet-poor citrated plasma, light blue (sodium citrate) top tube. Remove serum and citrated plasma from cells ASAP or within 2 hours of collection, transfer to individual plastic transport tubes and freeze. This test requires an automated platelet count performed on the EDTA whole blood sample at the client site. Record the platelet count on the test request form. Minimum specimen: 1.2 mL serum and 0.5 mL platelet-poor citrated plasma Unacceptable: Hemolyzed specimens. All required specimens not received. No platelet count received. Transport temp: CRITICAL FROZEN Method: Quantitative Nephelometry/Quantitative Enzymatic/Quantitative Spectrophotometry/Automated Cell Count/Electromagnetic Mechanical Clot Detection Unit code: 824579 CPT Code(s): 82977, 83883, 84450, 84460, 84520 Ref range: By report Reported: 1-5 days Liver-Kidney Microsome Antibody, IgG Order code: 82458 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.15 mL serum Unacceptable: Severely hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 824580 CPT Code(s): 86376 Ref range: <1:20 Normal Reported: 1-3 days Test List 10-294 BBPL Directory of Services Lorazepam Order code: 83970 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: High Performance Liquid Chromatography Unit code: 824600 CPT Code(s): 80154 Ref range: Dose-Related Range: 50-240 ng/mL -Dose (Adult): 1-10 mg/d Toxic: > 300 ng/mL Reported: 1-5 days Low Molecular Weight Heparin See: Heparin Anti-Xa Lower Respiratory Tract Culture See: Culture, Lower Respiratory Tract Loxapine Order code: 83980 Preferred specimen: 3.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 1.0 mL serum or plasma Other acceptable: 3.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tubes or gels. Transport temp: Room temperature Method: High Performance Liquid Chromatography S1 0 Unit code: 824650 CPT Code(s): 80299 Ref range: By report Reported: Within 10 days Ludiomil See: Maprotiline, Quantitative Luminal See: Phenobarbital 10-295 Test List BBPL Directory of Services Lupus Anticoagulant (LA) Screen & Confirmatory Panel Order code: 2030 Preferred specimen: 6.0 mL platelet-poor plasma, three 3.5 mL light blue (3.2% sodium citrate) top tubes. Blue top tubes must be filled to completion to ensure proper blood to anticoagulant ratio. Mix the tubes immediately by gentle inversion at least 6 times. Centrifuge immediately and remove the top two-thirds of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer 2.0 mL plasma into 3 separate plastic transport tubes and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: Three 1.0 mL aliquots of platelet-poor plasma. Notes: If possible, testing should be performed in the absence of warfarin therapy, or the history of current warfarin therapy should be provided on the test request form. Heparin therapy should be discontinued for 2 days prior to testing. Unacceptable: Serum, whole blood, hemolyzed, lipemic, clotted or non-frozen specimens. Specimens contaminated with heparin. Transport temp: CRITICAL FROZEN Method: Photo optic Unit code: 203000 CPT Code(s): 85610, 85613, 85730, 85732 Ref range: Prothrombin Time 11.0-14.0 Seconds aPTT 28.0-40.0 Seconds Silica Clotting Time (SCT) Seconds 0.0-50.0 Normalized SCT Ratio <1.2 dRVVT (LAC) Seconds 0.0-45.0 Normalized LAC Ratio <1.2 Reported: 1-3 days Lupus Inhibitor Panel with Reflex Order code: 84010 Preferred specimen: 6.0 mL platelet-poor plasma, three 3.5 mL light blue (3.2% sodium citrate) top tubes. Transfer 2.0 mL plasma aliquots into 3 separate transport tubes and freeze immediately. Ship on dry ice. Minimum specimen: Three 1.0 mL aliquots of platelet-poor plasma. Notes: Patient should not be receiving Coumadin (warfarin) for 1 week prior to testing, heparin, or direct thrombin inhibitors for 24 hours prior to testing as this can affect the assay results. Unacceptable: Serum, clotted, hemolzyed, or non-frozen specimens. S1 0 Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 299022 CPT Code(s): 85610, 85730 Ref range: By report Reported: 1-2 days Lupus Panel Order code: 84020 Preferred specimen: 5.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 3.0 mL serum Notes: Test includes: Anti-Nuclear Antibody Complement C3 & C4 dsDNA Antibody, IgG Mitochondrial M2 Antibody, IgG Sm/RNP Antibody, IgG SSA (Ro) Antibody, IgG SSB (La) Antibody, IgG Thyroglobulin Antibody Thyroid Peroxidase (TPO) Antibody Unacceptable: Plasma. Severely lipemic, grossly icteric, hemolyzed, or contaminated specimens. Transport temp: Refrigerated Method: Nephelometry/Chemiluminescent Immunoassay/Enzyme Immunoassay/Enzyme-Linked Immunosorbent Assay Unit code: 824751 CPT Code(s): 83516, 86038, 86160 (x2), 86225, 86235 (x3), 86376, 86800 Ref range: See individual tests. Reported: 1-3 days Lustral See: Sertraline Test List 10-296 BBPL Directory of Services Luteinizing Hormone Order code: 1287 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.3 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111095 CPT Code(s): 83002 Ref range: Females: Follicular phase 1.9-12.5 mIU/mL Mid-Cycle peak 8.7-76.3 mIU/mL Luteal Phase 0.5-16.9 mIU/mL Postmenopausal 15.9-54.0 mIU/mL Pregnant <0.1-1.5 mIU/mL Males: 20-70 years: 1.5-9.3 mIU/mL >70 years: 3.1-34.6 mIU/mL Reported: Within 24 hours Lyme Disease Antibody See: Borrelia burgdorferi DNA/PCR Borrelia burgdorferi Antibody, CSF Borrelia burgdorferi Antibodies, IgG & IgM Borrelia burgdorferi Antibodies, IgG & IgM by Western Blot Lymphocyte Mitogen Proliferation Order code: 82538 Preferred specimen: TIME SENSITIVE TEST. Contact BBPL Client Services before collecting specimens. Specimens should be received in the testing laboratory same day as drawn. Only draw patients on Monday through Thursday. Collect: One 10 mL green (sodium heparin) top tube (patient) and one normal control in a 10 mL green (sodium heparin) top tube from a healthy unrelated individual at approximately the same time as and under similar collection conditions as the patient. Label the control tube as such. Transport specimens at room temperature in the original collection tubes. CRITICAL AT ROOM TEMPERATURE. Do not refrigerate or freeze. S1 0 Minimum specimen: 7 mL whole blood patient and 7 mL normal control. Infant miniumum: 3 mL patient and 7 mL normal control Notes: Live lymphocytes required. Other acceptable: 10 mL yellow (ACD solution A) (patient) and 10 mL yellow (ACD solution A) (control) . Unacceptable: Yellow (ACD solution B) top tubes. Refrigerated or frozen specimens or specimens in transport longer than 12 hours. Transport temp: CRITICAL AT ROOM TEMPERATURE Method: Cell Culture Unit code: 825380 CPT Code(s): 86353 (x3) Ref range: By report Reported: 9-10 days Lymphocyte Subsets, Immunocompetency Order code: 35500 Preferred specimen: 3 mL EDTA whole blood, lavender top tube and 3 mL ACD-A whole blood, yellow top tube. Maintain specimens at room temperature. Do not freeze or refrigerate. Specimens must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL EDTA whole blood and 1.0 mL ACD-A whole blood. Notes: Includes: CD2 (Pan-T)% CD3 (Pan-T)% CD4 (Helper T)% CD8 (Suppressor T)% CD4/CD8 Ratio CD19 (Pan-B)% CD20 (Pan-B)% CD56 (NK)% Other acceptable: 1 yellow (ACD solution A) top tube and CBC results from same draw. Unacceptable: Hemolyzed, clotted, refrigerated or frozen specimens. Transport temp: Room temperature Method: Flow Cytometry Unit code: 535500 CPT Code(s): 88184, 88185 (x8) Reported: 3-5 days 10-297 Test List BBPL Directory of Services Lymphocyte Subsets, Immunodeficiency Panel Order code: 35450 Preferred specimen: 3 mL EDTA whole blood, lavender top tube and 3 mL ACD-A whole blood, yellow top tube. Maintain specimens at room temperature. Do not freeze or refrigerate. Specimens must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL EDTA whole blood and 1.0 mL ACD-A whole blood. Notes: Includes: CD3 T-Cell Count CD4 T-Helper Count CD8 T-Suppressor Count CD4/CD8 Ratio CD19 B-Cell Count CD16/CD56 NK-Cell Count Other acceptable: 1 yellow (ACD solution A) top tube and CBC results from same draw. Unacceptable: Hemolyzed, clotted, refrigerated or frozen specimens. Transport temp: Room temperature Method: Flow Cytometry Unit code: 535450 CPT Code(s): 86355, 86357, 86359, 86360 Reported: 3-5 days Lymphocyte Subsets, T-Cell CD4/CD8 Order code: 35470 Preferred specimen: 3 mL EDTA whole blood, lavender top tube and 3 mL ACD-A whole blood, yellow top tube. Maintain specimens at room temperature. Do not freeze or refrigerate. Specimens must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL EDTA whole blood and 1.0 mL ACD-A whole blood. Notes: Test includes: CD3 T-Cell Count CD4 T-Helper Count CD8 T-Suppressor Count CD4/CD8 Ratio CD4 T-Helper % Other acceptable: 3 mL EDTA whole blood, lavender top tube. Unacceptable: Hemolyzed, clotted, refrigerated or frozen specimens. Transport temp: Room temperature Method: Flow Cytometry Unit code: 535470 S1 0 CPT Code(s): 86359, 86360 Reported: 3-5 days Lymphoma (Aggressive) Panel by FISH Order code: 87928 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL bone marrow or 2.0 mL whole blood Notes: Probes included: IGH/BCL2, BCL6 and MYC. This panel is for the identification of double hit lymphoma and triple hit lymphoma, both of which show morphologic features intermediate between diffuse large B-Cell lymphoma and Burkitt Lymphoma. Both are aggressive lymphomas and are characterized by a poor survival rate. Other acceptable: 10.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807928 CPT Code(s): 88271 (x3), 88275 (x3), 88291 Ref range: By report Reported: Varies Test List 10-298 BBPL Directory of Services Lymphoma Immunophenotyping by Flow Cytometry Order code: 35408 Preferred specimen: Whole Blood: 5.0 mL whole blood, lavender (EDTA) top tube and/or 1 yellow (ACD solution A) top tube. Bone Marrow: 2.0 mL bone marrow submitted in a green (sodium heparin) top tube. After specimen is well mixed with anticoagulant, add equal amount of RPMI to the tube and invert to mix. Label specimen as bone marrow. Tissue: Fresh tissue submitted in 10-15 mL RPMI. Specimens must be received within 48 hours of collection. Do not freeze specimens. Notes: Includes: CD45, CD14, CD3, CD19, CD20, CD5, CD4, CD8, CD23, CD10, Kappa Light Chains, Lambda Light Chains. May include other antibodies as indicated by initial findings. Requisition should include suspected diagnosis and any available patient history. Unacceptable: Fixed or frozen specimens. Transport temp: Refrigerated Method: Flow Cytometry Unit code: 535408 CPT Code(s): 88184, 88185 (x13) Ref range: By report Reported: 1-3 days Lynch Syndrome See: Mismatch Repair Proteins by IHC Lyogen See: Fluphenazine Lysozyme, Serum Order code: 84085 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.4 mL specimen Other acceptable: 0.5 mL CSF, tears, or other body fluid in a leak-proof refrigerated. Indicate source on test request form. Unacceptable: Urine specimens S1 0 Transport temp: Refrigerated Method: Radial Immunodiffusion Unit code: 825400 CPT Code(s): 85549 Ref range: 9-17 µg/mL Reported: 1-5 days Macroprolactin Order code: 85435 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow specimen to clot at room temperature. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Unacceptable: EDTA plasma Transport temp: Frozen Method: Quantitative Chemiluminescent Immunoassay Unit code: 825435 CPT Code(s): 84146 (x2) Ref range: Prolactin: 1-9 years: Male/Female 2.1-17.7 ng/mL 10 years and older: Male 2.1-17.7 ng/mL; Female 2.8-26.0 ng/mL Monomeric Prolactin: 1-9 years: Male/Female 2.1-13.3 ng/mL 10 years and older: Male 2.1-13.3 ng/mL; Female 2.8-19.5 ng/mL Monomeric Prolactin Percent: Greater than 50%. Reported: 1-8 days 10-299 Test List BBPL Directory of Services Magnesium Order code: 1900 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 1.0 mL plasma, green (lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Xylidyl Blue Unit code: 103160 CPT Code(s): 83735 Ref range: 1.6-2.6 mg/dL Reported: Within 24 hours Magnesium, Fecal Order code: 84094 Preferred specimen: 5 gm aliquot from a well-mixed 24-hour or random stool collection in a clean unpreserved stool transport container. Stool must be liquid. Do not add saline or water to liquify specimen. Minimum specimen: 1 gm stool aliquot Notes: Indicate total collection time and weight. Unacceptable: Formed or viscous stool. Transport temp: Refrigerated Method: Spectrophotometry Unit code: 825500 CPT Code(s): 83735 Ref range: Magnesium, Fecal 0-110 mg/dL Magnesium, Fecal 24 hour 0-335 mg/d Reported: 2-3 days Magnesium, Ionized, Serum Order code: 82555 Preferred specimen: Collect one 5 mL serum gel-barrier tube. Centrifuge with stopper in place within 1 hour of collection. Do not open the tube. Submit the original collection tube. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 4.0 mL serum gel-barrier tube. Notes: Do not freeze gel-barrier tube. Do not expose specimen to air at any time during collection or transport process. Unacceptable: Opened serum gel-barrier tube, hemolysis, or plasma specimens. Transport temp: Refrigerated Unit code: 825551 CPT Code(s): 83735 Reported: 1-3 days Magnesium, RBCs Order code: 82549 Preferred specimen: 1.0 mL red blood cells (RBCs) from a trace metal-free royal blue (EDTA) top tube. Centrifuge whole blood within 45 minutes of collection and remove plasma from cells. Discard the plasma. Submit only the RBCs in the original royal blue top collection tube. Minimum specimen: 0.2 mL RBCs Other acceptable: 1.0 mL red blood cells (RBCs) from a green (sodium or lithium heparin), lavender (EDTA), or tan (lead free) top tube. Unacceptable: Serum or plasma Transport temp: Room temperature Method: Atomic absorption spectrometry (AAS); inductively-coupled plasma/mass spectrometry (ICP/MS) Unit code: 825549 CPT Code(s): 83735 Ref range: 4.2-6.8 mg/dL Reported: 2-3 days Magnesium, Urine Order code: 1047 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection (indicate if random) on both the urine container and test request form. Minimum specimen: 0.5 mL urine aliquot Unacceptable: Specimens with preservatives. Transport temp: Refrigerated Method: Xylidyl blue Unit code: 102473 CPT Code(s): 83735 Ref range: Excretion: 12-199 mg/day Reported: Within 24 hours Test List 10-300 S1 0 BBPL Directory of Services Malaria, Blood Smear Order code: 7130 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) top tube. Notes: Specimen must be received in laboratory within 24 hours of collection. Transport temp: Room temperature Method: Geimsa Stain Unit code: 409100 CPT Code(s): 87207 Ref range: No Plasmodium/Babesia species seen. Reported: 1-3 days Manganese, Blood Order code: 82561 Preferred specimen: 7.0 mL whole blood, royal blue (K EDTA) or (Na EDTA) top tube, in the original collection tube at room temperature or 2 refrigerated is also acceptable. 2 Minimum specimen: 1.0 mL whole blood Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patient should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) prior to specimen collection. Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na EDTA) tube. 2 Unacceptable: Heparin anticoagulant. Frozen specimens. Transport temp: Room temperature. Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 825601 CPT Code(s): 83785 Ref range: 4.2-16.5 µg/L Reported: 1-5 days Manganese, Urine S1 0 Order code: 84095 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Specimen must be collected in a plastic container and refrigerated during collection period. Submit urine in two Trace Element-Free transport tubes. Do not add acid preservative. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician) prior to specimen collection. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 825600 CPT Code(s): 83785 Ref range: Manganese, Urine 0.0-2.0 µg/L Manganese, Urine (24-hour) 0.0-2.0 µg/d Reported: 1-5 days Maprotiline, Quantitative Order code: 84100 Preferred specimen: 3.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.2 mL serum or plasma Other acceptable: 3.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated. Also acceptable: Room temperature or frozen. Method: Quantitative Gas Chromatography Unit code: 825650 CPT Code(s): 82491 Ref range: By report Reported: 3-6 days 10-301 Test List BBPL Directory of Services Maternal Serum Screen, Alpha Fetoprotein (Only) Order code: 80340 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. Minimum specimen: 0.5 mL serum Notes: Please submit Patient History for Maternal Serum Testing form. The following information on this form is required to perform maternal serum testing and must accompany the specimen in order for testing to be interpreted: patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. This test is used to screen for fetal risk of Open Neural Tube Defect (i.e., spina bifida). Unacceptable: Hemolyzed specimens or plasma. Transport temp: Refrigerated Method: Quantitative Chemiluminescent Immunoassay Unit code: 801200 CPT Code(s): 82105 Ref range: By report Reported: 2-3 days Maternal Serum Screen, Alpha Fetoprotein, hCG, & Estriol Order code: 81325 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells ASAP or witihin 2 hours of collection and transfer to a plastic transport tube. Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. Minimum specimen: 0.5 mL serum Notes: Please submit Patient History for Maternal Serum Testing form. The following information on this form is required to perform maternal serum testing and must accompany the specimen in order for testing to be interpreted: patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. This test is used to screen for fetal risk of Down syndrome (trisomy 21), trisomy 18, and Open Neural Tube Defect (ONTD, spina bifida). Unacceptable: Hemolyzed specimens or plasma. Transport temp: Refrigerated Method: Quantitative Chemiluminescent Immunoassay Unit code: 801325 S1 0 CPT Code(s): 82105, 82677, 84702 Ref range: By report. Includes AFP, hCG, and Estriol. Intervals are based upon weeks of gestation. Reported: 2-3 days Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A Order code: 87225 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. Minimum specimen: 1.0 mL serum Notes: Please submit Patient History for Maternal Serum Testing form. The following information on this form is required to perform maternal serum testing and must accompany the specimen in order for testing to be interpreted: patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. This test is used to screen for fetal risk of Down syndrome (trisomy 21), trisomy 18, and Open Neural Tube Defect (ONTD, spina bifida). Unacceptable: Hemolyzed specimens or plasma. Transport temp: Refrigerated Method: Quantitative Chemiluminescent Immunoassay Unit code: 827225 CPT Code(s): 82105, 82677, 84702, 86336 Ref range: By report. Includes AFP, hCG, Estriol, and Inhibin A. Intervals are based upon weeks of gestation. Reported: 2-3 days Test List 10-302 BBPL Directory of Services Maternal Serum Screen, First Trimester Order code: 81503 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Specimen must be drawn in the first trimester between 11 weeks, 0 days, and 13 weeks, 6 days. (CrownRump length (CRL) must be between 4.2-8.5 cm). Minimum specimen: 1.0 mL serum Notes: This test requires a nuchal translucency (NT) measurement that has been performed by a certified ultrasonographer. The ultrasonographer MUST be certified to perform NT measurements by one of the following agencies: Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR). If an NT is unobtainable, order the Maternal Serum Integrated Screening 1 and 2, which can be interpretated without an NT value. Please submit Patient History for Maternal Serum Testing form. The following information on this form is required to perform maternal serum testing and must accompany the specimen in order for testing to be interpreted: a crown-rump length measurement (cm), ultrasonographer's name and certification number, date of ultrasound, patient's date of birth, current weight, due date, number of fetuses present, patient's race, if the patient has had a previous pregnancy with a chromosome abnormality, physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. This test does not screen for Open Neural Tube Defect (ONTD). This test is used to screen for fetal risk of Down syndrome (trisomy 21) and trisomy 18. Unacceptable: Hemolyzed specimens or plasma. A crown-rump length greater than 8.5 cm. Transport temp: Refrigerated Method: Quantitative Chemiluminescent Immunoassay Unit code: 815030 CPT Code(s): 84163, 84702 Ref range: By report Reported: 2-4 days Maternal Serum Screening, Integrated, Specimen #1 Order code: 82566 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. The nuchal translucency (NT) measurement is preferred; however, the Integrated Maternal Screen can be interpreted with or without a NT measurement. If NT measurement is performed specimen must be drawn between 10 weeks, 3 days and 13 weeks, 6 days gestation (CrownRump length (CRL) must be 3.6-8.5 cm). Serum only specimens may be drawn between 10 weeks, 0 days and 13 weeks, 6 days gestation (Crown-Rump length (CRL) must be 3.2-8.5 cm). The specimen collection and ultrasound date may be different. Minimum specimen: 0.3 mL serum Notes: The final Integrated Maternal Screen can be interpreted with or without a nuchal translucency (NT) measurement. The NT measurement must also be performed by an ultrasonographer that is certified by one of the following agencies: Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR). Please submit Patient History for Maternal Serum Testing form. The following information on this form is required to perform maternal serum testing and must accompany the specimen in order for testing to be interpreted: patient's date of birth, current weight, number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor at donation. In addition to the above: If a NT measurement is performed: the date of ultrasound,the CRL measurement, the NT measurement and the name and certification number of the sonographer is required. or If no NT measurement is performed: a due date or CRL measurement with the date of ultrasound is required. S1 0 Unacceptable: Hemolyzed specimens or plasma. Transport temp: Refrigerated Method: Quantitative Chemiluminescent Immunoassay Unit code: 825660 CPT Code(s): 84163 Ref range: By report The first specimen of an Integrated Maternal Serum Screening is used to measure PAPP-A. Final interpretative report will be available when the second specimen test results are complete. Reported: 2-4 days 10-303 Test List BBPL Directory of Services Maternal Serum Screening, Integrated, Specimen #2 Order code: 82661 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Specimen must be drawn between 15 weeks, 0 days and 24 weeks, 6 days gestation. Requires a previously submitted first trimester specimen, Maternal Serum Screening, Integrated, Specimen #1 (82566). Minimum specimen: 1.0 mL serum Notes: Second part of a 2-part test. Requires that the first part (Maternal Serum Screening, Integrated, Specimen #1) was submitted in the first trimester. Risks determined using a combination of 1st and 2nd trimester serum markers, with or without 1st trimester nuchal translucency (NT) measurement. The patient demographic information provided with the Integrated, Specimen #1 will used to calculate the risks for this report. Please submit Patient History for Maternal Serum Testing form. The information on this form is required to perform maternal serum testing and must accompany the specimen in order for testing to be interpreted. Unacceptable: Hemolyzed specimens or plasma. Transport temp: Refrigerated Method: Quantitative Chemiluminescent Immunoassay Unit code: 825661 CPT Code(s): 82105, 82677, 84702, 86336 Ref range: By report. Includes AFP, hCG, Estriol, Inhibin A, and previous PAPP-A. Intervals are based upon weeks of gestation. Reported: 2-4 days MDS Panel by FISH See: Myelodysplastic Syndrome (MDS) Panel by FISH Measles See: Rubella Antibody, IgG Rubella Antibody, IgM Rubeola Antibody, IgG Rubeola Antibody, IgM Rubeloa Antibodies, IgG & IgM Measles, Mumps, Rubella Immunity Panel Order code: 94626 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. S1 0 Minimum specimen: 0.9 mL serum Notes: Test includes: Measles (Rubeola) Antibody, IgG Mumps Virus Antibody, IgG Rubella Antibody, IgG Unacceptable: Hemolyzed, lipemic, heat-inactivated, or contaminated specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay (CLIA) Unit code: 94626 CPT Code(s): 86735, 86762, 86765 Ref range: Measles (Rubeola) Antibody, IgG: Negative: <25.0 AU/mL Equivocal: 25.0-29.9 AU/mL Positive: >29.9 AU/mL Mumps Virus Antibody, IgG: Negative: <9.0 AU/mL Equivocal: 9.0-10.9 AU/mL Positive: >10.9 AU/mL Rubella Antibody, IgG: Non-Immune: < 5.0 IU/mL Equivocal: 5.0-9.9 IU/mL Immune: >10.0 IU/mL Reported: 1-3 days Mebaral See: Mephobarbital Test List 10-304 BBPL Directory of Services Melanin, Urine Order code: 84110 Preferred specimen: 4.0 mL urine aliquot from a well-mixed random urine collection. Transfer urine aliquot to a plastic amber transport tube and freeze. Protect from light during collection, storage, and shipment. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 2.5 mL urine aliquot Unacceptable: Specimens exposed to light. Refrigerated or room temperature specimens. Transport temp: CRITICAL FROZEN Method: Qualitative Colorimetry Unit code: 825700 CPT Code(s): 81005 Ref range: Negative Reported: 1-2 days Melanocyte Stimulating Hormone, Alpha Order code: 85705 Preferred specimen: 3.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Patients should not be on any steroid, ACTH, or hypertension medication, if possible, for at least 48 hours prior to specimen collection. Morning fasting specimens are prefered; non fasting specimens are acceptable. Minimum specimen: 1.0 mL plasma Unacceptable: Refrigerated or room temperature specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Radioimmunoassay Unit code: 825705 CPT Code(s): 83519 Ref range: By report Reported: 7-13 days Mellaril See: Thioridazine and Mesoridazine S1 0 Meperidine and Metabolite Order code: 82578 Preferred specimen: 2.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum or plasma Notes: Drugs covered: Meperidine and Normeperidine (Meperidine metabolite). For medical purposes only; not valid for forensic use. Other acceptable: 2.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Plasma or whole blood from light blue (sodium citrate) top tubes. Transport temp: Refrigerated Method: Liquid Chromatography-Tandem Mass Spectrometry Unit code: 825780 CPT Code(s): 83925 Ref range: Positive cutoff: Meperidine: 2 ng/mL; Normeperidine: 5 ng/mL Reported: 2-8 days Mephobarbital Order code: 84140 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Order phenobarbital (order code 1190) separately. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Gas Chromatography-Mass Spectrometry Unit code: 825800 CPT Code(s): 82205 Ref range: Dose-Related Range: 1-7 µg/mL Dose (Adult): 200-600 mg/d Greater than 15 µg/mL Reported: 1-5 days 10-305 Test List BBPL Directory of Services Meprobamate Order code: 84150 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin) or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Gas Chromatography Unit code: 825850 CPT Code(s): 83805 Ref range: Therapeutic Range: 5-20 µg/mL Toxic: > 40 µg/mL Reported: 1-4 days Meprospan See: Meprobamate Mercaptopurine and Metabolites, Blood Order code: 82588 Preferred specimen: 1.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 0.4 mL whole blood Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 825880 Ref range: By report Reported: 3-10 days Mercaptopurine, Serum or Plasma Order code: 82596 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 2.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tube or gels. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatograpy with Ultraviolet Detection Unit code: 825960 CPT Code(s): 82491 Ref range: <1000 ng/mL; Report Limit 20 ng/mL Reported: 6-7 days Mercury, Blood Order code: 84161 Preferred specimen: 7.0 mL whole blood, royal blue (K EDTA) or (Na EDTA) top tube, in the original collection tube at room temperature or 2 refrigerated is also acceptable. 2 Minimum specimen: 1.0 mL whole blood Notes: Patient should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-thecounter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours prior to collection. Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na EDTA) tube. 2 Unacceptable: Heparin anticoagulant. Frozen specimens. Transport temp: Room temperature Method: Quantitative Atomic Absorption/Quantitative Inductively Coupled Plasma-Mass Spectrometry Unit code: 825900 CPT Code(s): 83825 Ref range: 0-10 µg/L Mercury is volatile; concentration may reduce after seven or more days of storage. This test measures total mercury, whereas the reference interval relates to inorganic mercury concentrations. Dietary and nonoccupational exposure to organic mercury species may contribute to an elevated total mercury result. Reported: 1-2 days Test List 10-306 S1 0 BBPL Directory of Services Mercury, Urine Order code: 84160 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour collection or random urine. Specimen must be collected in a plastic container and should be refrigerated during collection period. Submit urine in two Trace Element-Free transport tubes. Do not add acid preservative. Record total volume and hours of collection on the both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician) prior to specimen collection. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended. Unacceptable: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media or acid preserved urine. Transport temp: Refrigerated Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 825950 CPT Code(s): 83825 Ref range: Mercury, Urine - per volume: 0-10 µg/L Mercury, Urine - per 24-hour: 0-15 µg/d Mercury, Urine - ratio to CRT: Less than or equal to 35 ug/gCR Reported: 1-4 days Mesoridazine Order code: 84170 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Remove serum or plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) Unit code: 826000 CPT Code(s): 84022 Ref range: By report Reported: 9-12 days S1 0 Metanephrines Fractionated, Urine Order code: 82651 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.5 mL urine aliquot Notes: If possible patient should abstain from medications for 72 hours prior to collection. Unacceptable: Room temperature specimens. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 826251 CPT Code(s): 83835 Ref range: 0-17 years: Reference ranges not established 18 years and older: Metanephrine: 30-350 µg/d Normetanephrine: 50-650 µg/d Reported: 1-4 days Metanephrines, Plasma (Free) Order code: 82649 Preferred specimen: 1.0 mL plasma, chilled lavender (EDTA) top tube. Invert tube to mix with preservatives. Centrifuge and transfer plasma to a plastic transport tube, refrigerate. The whole blood specimen may be kept refrigerated for as long as 2 hours before centrifugation. Minimum specimen: 0.4 mL plasma Notes: Patient should be fasting overnight (water and noncaffeinated soft drinks are permissible). The patient should be in a supine position for at least 15 minutes before and during specimen collection. It is preferable, but not essential, to draw the specimen without a tourniquet. Unacceptable: Heparinzed plasma. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spetrometry Unit code: 826249 CPT Code(s): 83835 Ref range: Normetanephrine: 0-145 pg/mL Metanephrine: 0-62 pg/mL Reported: 2-7 days 10-307 Test List BBPL Directory of Services Methadone & Metabolite, Serum or Plasma See: Drug Confirmation/Quantitation - Methadone & Metabolite, Serum or Plasma Methadone Confirmation, Quantitative, Urine Order code: 81744 Preferred specimen: 20 mL random urine in a clean plastic urine container. Minimum specimen: 10 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 812744 CPT Code(s): 83840 Ref range: By report Reported: 5-7 days Methanol, Serum or Plasma Order code: 80381 Preferred specimen: 3.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a tightly-capped plastic transport tube to minimize alcohol loss. Minimum specimen: 0.5 mL serum or plasma Notes: For medical purposes only. Other acceptable: 3.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection and transfer to a tightly-capped plastic transport tube. Sodium fluoride/potassium oxalate whole blood may be transported in the original container. Do not freeze whole blood. Transport temp: Refrigerated Method: Quantitative Gas Chromatography Unit code: 801750 CPT Code(s): 84600 Ref range: No therapeutic range - Test detection limit 5 mg/dL Toxic: > 20 mg/dL Toxic concentrations may cause intoxication, metabolic acidosis, ocular toxicity, CNS depression and fatality if patients do not receive medical treatment. Reported: 1-2 days Methemoglobin, Blood Order code: 84210 Preferred specimen: 3.0 mL whole blood, green (sodium or lithium heparin) top tube. Refrigerate immediatey after collection. Submit original full, unopened tube. Do not centrifuge. Specimen must be received in laboratory within 4 hours after collection. Unacceptable: EDTA, frozen or clotted specimens. Transport temp: Refrigerated Unit code: 826450 CPT Code(s): 83050 Ref range: 0-1.5 % Reported: Within 24 hours Methicillin-resistant Staphylococcus aureus (MRSA), NAA Order code: 82727 Preferred specimen: Collect using BBL™ CultureSwab Liquid Stuart swab. Moisten the swab with two drops (about 50 uL) sterile physiological saline or use it dry. Carefully insert the swab into the patient's nostril (the swab tip must be inserted up to 2.5 cm (1 inch) from the edge of the nares). Roll the swab five times. Insert the swab into the second nostril and repeat sampling. Place the swab in its container and label the container. BBL™ CultureSwab Liquid Stuart swabs are available through BBPL Client Services. Do not collect using the Culture Swab II Liquid Stuart Media that contains 2 swabs or any swab besides BBL™ CultureSwab Liquid Stuart swab. Minimum specimen: One swab (BBL™ CultureSwab Liquid Stuart). Notes: MRSA by NAA is a qualitative in vitro diagnostic test for the direct detection of nasal colonization by methicillin-resistant Staphylococcus aureus (MRSA) to aid in the prevention and control of MRSA infections in healthcare settings. Unacceptable: Inappropriate transport or storage conditions. More than one swab or any swab besides BBL™ CultureSwab Liquid Stuart swab. Expired swab transport. Wire-shaft swab. Transport temp: Refrigerated Method: Nucleic acid amplification (NAA) Unit code: 827227 CPT Code(s): 87641 Ref range: By report Reported: 5-6 days Test List 10-308 S1 0 BBPL Directory of Services Methotrexate Order code: 84231 Preferred specimen: 1.0 mL serum, red top tube, or plasma, green (lithium heparin) top tube. Do not collect in SST. Remove serum or plasma from cells ASAP, transfer to a plastic amber transport tube and freeze. Protect from light during collection, storage, and shipment. If amber tubes are not available, wrap transport tube in aluminum foil to protect from light. Minimum specimen: 0.5 mL serum or plasma Unacceptable: Separator tubes or gels. Transport temp: Frozen Method: Immunoassay Unit code: 826550 CPT Code(s): 80299 Ref range: 0.00-0.05 µmol/L Reported: Within 24 hours Methsuximide & Normethsuximide Order code: 84240 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin) or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Gas Chromatography Unit code: 826650 CPT Code(s): 83858 Ref range: Therapeutic Range: Methsuximide: < 1 µg/mL Normethsuximide: 10-40 µg/mL Total: 10-40 µg/mL Toxic - total: > 60 µg/mL Reported: 1-5 days S1 0 Methylmalonic Acid, Serum or Plasma Order code: 82675 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 0.6 mL serum or plasma Notes: Remove serum or plasma from cells within 1 hour of collection and transfer to a plastic transport tube. Other acceptable: 2.0 mL plasma, green (sodium or lithium heparin) top tube. Unacceptable: Plasma from light blue or yellow top tubes. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 826705 CPT Code(s): 83921 Ref range: 0-378 nmol/L Reported: Within 7 days Methylmalonic Acid, Urine Order code: 82676 Preferred specimen: 5.0 mL random urine in a plastic urine container, no preservative. Minimum specimen: 0.6 mL urine Transport temp: Refrigerated Method: Gas chromatography/mass spectrometry (GC/MS) Unit code: 826706 CPT Code(s): 83921 Ref range: 0.4-2.5 µmol/mmol crt Reported: 1-3 days 10-309 Test List BBPL Directory of Services Methylphenidate & Metabolite Order code: 85240 Preferred specimen: 2.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 1.0 mL serum or plasma Notes: Remove serum or plasma from cells ASAP and freeze within 6 hours of collection. Separate specimens must be submitted when multiple tests are ordered. Specimen should be collected 1-6 hours after dosing. Drugs covered: Methylphenidate and ritalinic acid. Other acceptable: 2.0 mL plasma, lavender (EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Unacceptable: Light blue (sodium citrate). Hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Liquid Chromatography/Tandam Mass Spectrometry Unit code: 826715 CPT Code(s): 80299 Ref range: Positive Cutoff: Methylphenidate: 1 ng/mL Ritalinic acid: 10 ng/mL Reported: 1-7 days Mexiletine Order code: 84260 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 826750 CPT Code(s): 80299 Ref range: Therapeutic Range: 1.0-2.0 µg/mL Toxic Level: Greater than 2.0 µg/mL Reported: 1-5 days Microalbumin, 24 Hour Urine Order code: 1536 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour urine collection. Refrigerate 24-hour specimen during collection. Do not add preservatives or store urine in glass containers. Record the total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Notes: Includes creatinine excretion-24 hour. Unacceptable: Urine with preservatives. Frozen urine. Urine in glass containers. Transport temp: Refrigerated Method: Nephelometry Unit code: 102602 CPT Code(s): 82043, 82570 Ref range: Less than 30 mg/day Reported: 1-2 days Microalbumin, Random Urine - Microalbumin/Creatinine Ratio Order code: 1538 Preferred specimen: 5.0 mL random urine in a plastic urine container with no preservatives. Do not use glass urine containers or freeze specimen. Minimum specimen: 1.0 mL urine Unacceptable: Urines with preservatives. Frozen urine. Urine in glass containers. Transport temp: Refrigerated Method: Nephelometry Unit code: 102599 CPT Code(s): 82043, 82570 Ref range: Less than 30 mg/g creat Reported: 1-2 days Test List 10-310 S1 0 BBPL Directory of Services Microsatellite Instability (MSI) by PCR Order code: 32245 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block (0.2 cm³ piece of tissue) of tumor tissue and one block of normal tissue. If no normal tissue is available, 5 mL whole blood, lavender (EDTA) top tube or 1 mL bone marrow (EDTA) may be used as a normal control. Transport temp: Room temperature Method: Polymerase Chain Reaction (PCR) Unit code: 532245 CPT Code(s): 81301, 88381, G0452 Ref range: By report Reported: Within 7 days Microsporidia Kinyoun Stain Order code: 7410 Preferred specimen: 1 g stool (pea size portion) in 10% formalin vial. Notes: Microsporidia are not detected by the Ova and Parasite exam. Unacceptable: Stool specimen submitted in preservatives other than 10% formalin or unpreserved stool specimen. Transport temp: Room temperature Method: Kinyoun Carbolfuchsin Stain Unit code: 408010 CPT Code(s): 87207 Ref range: Negative Reported: 1-3 days Midol See: Ibuprofen Miltown, Serum See: Meprobamate S1 0 Mismatch Repair Proteins by IHC Order code: 32240 Preferred specimen: Formalin-fixed, paraffin-embedded (FFPE) tissue block containing colorectal cancer. Notes: BRAF IHC will be added and reported when clinically indicated by a pathologist. Additional charges may apply. Transport temp: Room temperature Method: Immunohistochemistry (IHC) Unit code: 532240 CPT Code(s): 88360 (x4) Ref range: By report Reported: Within 5 days Misural See: Librium & Nordiazepam Mitochondrial M2 Antibody, IgG Order code: 80780 Preferred specimen: 0.5 mL red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Unacceptable: Plasma. Grossly icteric, severely lipemic, hemolyzed, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 827100 CPT Code(s): 83516 Ref range: 20.0 Units or less: Negative 20.1-24.9 Units: Equivocal 25.0 Units or greater: Positive Reported: 1-2 days Mitran See: Librium & Nordiazepam 10-311 Test List BBPL Directory of Services MMR Proteins by IHC See: Mismatch Repair Proteins by IHC Moditen See: Fluphenazine Molipaxin See: Trazodone Monilia Culture See: Culture, Yeast Mono Test, Heterophile Screen Order code: 2295 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Unacceptable: Grossly hemolyzed specimens. Transport temp: Refrigerated Method: Hemagglutination Unit code: 352200 CPT Code(s): 86308 Ref range: Negative Reported: Within 24 hours Mono, Heterophile Screen Reflex Order code: 2205 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.2 mL serum S1 0 Notes: If mono screen is negative, EBV Comprehensive Profile will be added at an additional charge. Unacceptable: Grossly hemolyzed specimens. Transport temp: Refrigerated Method: Hemagglutination Unit code: 352205 CPT Code(s): 86308 Ref range: Negative Reported: Within 24 hours Morphine See: Drug Confirmation, Quantitation Opiates, Serum or Plasma Test List 10-312 BBPL Directory of Services Motor and Sensory Neuropathy Evaluation with Reflex to Titer and Neuronal Western Blot Order code: 82716 Preferred specimen: 2.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Notes: PCCA/ANNA antibodies are screened by IFA. If the IFA screen is positive at 1:10 or greater, then a titer (PCCA or ANNA) and immunoblot will be added at an additional charge. Unacceptable: Plasma, CSF, or other body fluids. Contaminated, heat-inactivated, hemolyzed, severely icteric, or lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Western Blot Unit code: 827156 CPT Code(s): 83516 (x7), 86255 Ref range: Purkinje Cell/Neuronal Nuclear IgG Screen: None Detected Neuronal Nuclear Antibody (ANNA) IFA Titer, IgG: Less than 1:10 Purkinje Cell Antibody, Titer: Less than 1:10 Neuronal Nuclear (Hu, Ri, and Yo) Antibodies IgG by Western Blot: None Detected Myelin Associated Glycoprotein (MAG) Antibody, IgM: Less than 1000 TU Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibody, IgM: Less than 1.00 IV Asialo-GM1 Antibodies, IgG/IgM; GM1 Antibodies, IgG/IgM; GD1a Antibodies, IgG/IgM; GD1b Antibodies, IgG/IgM; GQ1b Antibodies, IgG/IgM: 29 IV or less: Negative 30-50 IV: Equivocal 51-100 IV: Positive 101 IV or greater: Strong Positive Reported: 1-9 days Motor Neuropathy Panel Order code: 87151 Preferred specimen: 4.0 mL serum, SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 2.0 mL serum Notes: Test includes: Ganglioside (asialo-GM1) Antibody, IgG/IgM Ganglioside (GM1) Antibody, IgG/IgM Ganglioside (GD1a) Antibody, IgG/IgM Ganglioside (GD1b) Antibody, IgG/IgM Ganglioside (GQ1b) Antibody, IgG/IgM Protein Electrophoresis Immunoglobulins G, A, M Myelin Associated Glycoprotein (MAG) Antibody, IgM Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibody, IgM S1 0 Unacceptable: Contaminated, heat-inactivated, hemolyzed, severely icteric, or lipemic specimens. Room temperature specimens. Plasma, CSF, urine or other body fluids. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay, Electrophoresis, Nephelometry Unit code: 827151 CPT Code(s): 82784 (x3), 83516 (x7), 84160, 84165, 86334 Ref range: By report Reported: 2-8 days Motrin See: Ibuprofen MPA See: Mycophenolic Acid and Metabolite MPD Panel by FISH See: Myeloproliferative Disorders Panel by FISH 10-313 Test List BBPL Directory of Services MPL Codon 515 Mutation Detection Order code: 82276 Preferred specimen: 5.0 mL whole blood or bone marrow, lavender (EDTA) top tube. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: The test will detect and quantify MPL codon 515 mutation, including W515K and W515L. Testing includes pathologist's interpretation. Unacceptable: Plasma or serum. Specimens collected in anticoagulants other than EDTA. Clotted or grossly hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction/Quantitative Pyrosequencing Unit code: 822726 Ref range: By report Reported: 7-12 days MPO/PR3 See: Anti-Neutrophil Cytoplasmic Antibodies MRSA (ORSA) Culture Order code: 3204 Preferred specimen: Specimen should be submitted in a tightly sealed sterile container or submitted using sterile culture swabs. Stool specimens: submitted in Cary-Blair transport media. Note source of specimen on test request form. Unacceptable: Dried culture swab or wooden shaft swab. Transport temp: Cary-Blair media and swabs are kept at room temperature; all other specimens should be refrigerated. Method: Routine Culture Technique Unit code: 402330 CPT Code(s): 87081 Reported: Within 48 hours MSI by PCR See: Microsatellite Instability (MSI) by PCR MTHFR (Methylenetetrahydrofolate Reductase) Gene Mutation (C677T & A1298C) Order code: 36483 Preferred specimen: 5.0 mL whole blood collected in lavender (EDTA), light blue (sodium citrate), or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Notes: Separate specimens should be submitted when multiple tests are ordered. Other acceptable: Liquid Based PAP Media Unacceptable: Heparin anticoagulant, severely hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 536483 CPT Code(s): 81291 Ref range: By report Reported: 3-7 days Mucopolysaccharides, Quantitative, Urine Order code: 84326 Preferred specimen: 10.0 mL random urine collection (early morning preferred). Freeze urine immediately. Notes: Patient's age is required. Unacceptable: Contaminated or non-frozen specimens. Specimens containing preservatives. Transport temp: Frozen Method: Spectrophotometry Unit code: 827250 CPT Code(s): 83864 Ref range: By report Reported: 3-9 days Mullerian-Inhibiting Hormone See: Anti-Mullerian Hormone Test List 10-314 S1 0 BBPL Directory of Services Multiple Myeloma Panel by FISH Order code: 80795 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transfered into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory same day as collection. Minimum specimen: 1 mL bone marrow or 2 mL whole blood Notes: Please submit a Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) studies. Complete the form and submit with the test request form and specimen. Fluorescence in situ hybridization (FISH) panel is performed on CD138+ sorted cells (assuming specimen is sufficient for sorting) for multiple myeloma prognosis-specific genomic abnormalities: CKS1B (1q gain), ASS1 (+9), CCND1/IGH(IGH/CCND1 fusion or +11), IGH rearrangement, PML (+15) and p53 (17p deletion). If IGH is positive and not partnered with CCND1, additional testing will include FGFR3/IGH and MAF/IGH. Additional charges will apply. Other acceptable: 10.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted of paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807925 CPT Code(s): 88271 (x6), 88275 (x6), 88291 Ref range: By report Reported: 5-14 days Multiple Sclerosis Profile Order code: 94095 Preferred specimen: Collect 2.5 mL CSF and 1.5 mL serum, red top tube or SST, at the same time (within 8 hours of each other). Refrigerate. Minimum specimen: 1.0 mL CSF and 0.6 mL serum Notes: Test includes: CSF Protein Analysis, Oligoclonal Bands, and Myelin Basic Protein. Unacceptable: Extremely lipemic serum specimens. Plasma. CSF and serum not collected within 8 hours of each other. Method: Enzyme-Linked Immunosorbent Assay, Isoelectric Focusing/Immunoblot, Nephelometry Unit code: 94095 CPT Code(s): 82040, 82042, 82784 (x2), 83873, 83916 Ref range: By report Reported: 2-6 days S1 0 Multom See: Librium & Nordiazepam Mumps Virus Antibody, IgG Order code: 84340 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Notes: Acute and convalescent specimens should be submitted on separate test request forms. Please mark specimens as "acute" or "convalescent". Test is used to determine immunity to mumps virus. Unacceptable: Hemolysis, lipemia, gross bacterial contamination. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay (CLIA) Unit code: 827450 CPT Code(s): 86735 Ref range: Negative: <9.0 AU/mL Equivocal: 9.0-10.9 AU/mL Positive: >10.9 AU/mL Reported: 1-3 days Mumps Virus Antibody, IgM Order code: 82746 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Test is used to diagnosis acute mumps infection. Unacceptable: Hemolysis, lipemia, gross bacterial contamination. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 827460 CPT Code(s): 86735 Ref range: Negative: <0.80 Borderline: 0.80-1.20 Positive: >1.20 Reported: 1-3 days 10-315 Test List BBPL Directory of Services Muramidase, Serum See: Lysozyme Muscle-Specific Receptor Tyrosine Kinase See: MuSK Antibody Titer MuSK Antibody Titer Order code: 87510 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum Unacceptable: Do not freeze. Transport temp: Refrigerated Method: Radioimmunoassay (RIA) Unit code: 827510 Ref range: Negative: <10 Borderline: 10 Positive: >20 Reported: 7-14 days Myasthenia Gravis Panel Order code: 87551 Preferred specimen: 1.5 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.7 mL serum Notes: Test includes: ACHR Binding Antibody ACHR Blocking Antibody ACHR Modulating Antibody Striated Muscle Antibody, IgG If Striated Muscle Ab is greater than or equal to 1:40, then a titer will be added at an additional charge. Unacceptable: Plasma. Hemolyzed, lipemic, or contaminated specimens. Transport temp: Refrigerated Method: Quantitative Radioimmunoassay/Semi-Quantitative Flow Cytometry/Semi-Quantitative Indirect Fluorescent Antibody S1 0 Unit code: 827551 CPT Code(s): 83516 (x2), 83519, 86255 Ref range: Acetylcholine Receptor Binding Antibody: Negative: 0.0-0.4 nmol/L Positive: 0.5 nmol/L or greater Acetylcholine Receptor Blocking Antibody: Negative: 0-26% blocking Indeterminate: 27-41% blocking Positive: 42% or greater blocking Acetylcholine Receptor Modulating Antibody: Negative: 0-45% modulation Positive: 46% or greater modulation Striated Muscle Antibody, IgG: Screen: < 1:40 No antibody detected. Titer: < 1:40 No antibody detected. Reported: 3-5 days Myasthenia Gravis/Lambert-Eaton Syndrome Evaluation Order code: 82406 Preferred specimen: 3.0 mL serum, red top tube or SST. Patient should have no general anesthetic or muscle-relaxant drugs in the previous 24 hours. Minimum specimen: 2.0 mL serum Notes: Test includes: P/Q-Type Calcium Channel Antibody N-Type Calcium Channel Antibody ACh Receptor (Muscle) Binding Antibody ACh Receptor (Muscle) Modulating Antibody Striational (Striated Muscle) Antibody If AChR modulating antibodies are > or =90% and striational antibodies are > or =1:60, AChR ganglionic neuronal antibody and CRMP-5-IgG Western blot will be performed at an additional charge. Unacceptable: Grossly hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Radioimmunoassay/Enzyme Immunoassay Unit code: 824060 CPT Code(s): 83519 (x5), 83520, 84182 Ref range: By report Reported: 7-14 days Test List 10-316 BBPL Directory of Services MYC Rearrangement See: Chromosome Analysis, FISH-Interphase Mycobacterium Culture & Stain See: Culture, Acid Fast Bacilli with Stain Mycobacterium Stain See: Acid Fast Bacilli, Stain Only Mycobacterium tuberculosis Detection, Nucleic Acid Amplification (NAA) Order code: 82761 Preferred specimen: 5.0 mL sputum, respiratory aspirate, lavage fluid, or pleural fluid or 1.0 mL CSF, or small piece of respiratory tissue (2 mm fron needle biopsy). Transport specimen in sterile screw-cap container. Seal cap tightly. Specimen must be received in laboratory within 48 hours of collection. Indicate souce on test request form. Minimum specimen: 5 mL sputum, respiratory aspirate, lavage fluid, pleural fluid, or 1 mL CSF. Notes: When collecting sputum, have the patient brush teeth or remove dentures and rinse mouth with water. Instruct the patient not to collect saliva. When collecting aspirates, use standard aseptic preparation. Respiratory tissue specimens may be fresh or frozen. Unacceptable: Blood and bone marrow are not suitable for amplification test. Tissue not of respiratory origin will not be tested. Transport temp: Refrigerated Method: Nucleic acid amplification (NAA) Unit code: 827601 CPT Code(s): 87556 Ref range: Negative Reported: 4-7 days Mycophenolate See: Mycophenolic Acid and Metabolite S1 0 Mycophenolic Acid and Metabolite Order code: 82764 Preferred specimen: 1.2 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Do not collect in SST. Minimum specimen: 0.3 mL serum or plasma Other acceptable: 1.2 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 827641 CPT Code(s): 80180 Ref range: By report Reported: 2-4 days Mycoplasma pneumoniae Antibodies, IgG & IgM Order code: 82777 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Unacceptable: Severely lipemic, hemolyzed, icteric, heat-inactivated, or contaminated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 827770 CPT Code(s): 86738 (x2) Ref range: Mycoplasma pneumoniae Antibody, IgG: < 0.10 U/L: Negative 0.10-0.32 U/L: Equivocal > 0.32 U/L: Positive Mycoplasma pneumoniae Antibody, IgM: 0.76 U/L or less: Negative - No clinically significant amount of M. pneumoniae IgM antibody detected. 0.77-0.95 U/L: Low Positive - M. pneumoniae-specific IgM presumptively detected. Collection of a follow-up sample in one to two weeks is recommended to assure reactivity. 0.96 U/L or greater: Positive - Highly significant amount of M. pneumoniae-specific IgM antibody detected. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. Reported: 1-3 days 10-317 Test List BBPL Directory of Services Mycoplasma pneumoniae Antibody, IgG Order code: 82776 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Unacceptable: Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 827760 CPT Code(s): 86738 Ref range: < 0.10 U/L: Negative 0.10-0.32 U/L: Equivocal > 0.32 U/L: Positive Reported: 1-3 days Mycoplasma pneumoniae Antibody, IgM Order code: 82775 Preferred specimen: 0.5 mL serum, SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum Notes: Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent". Unacceptable: Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 827765 CPT Code(s): 86738 Ref range: 0.76 U/L or less: Negative - No clinically significant amount of M. pneumoniae IgM antibody detected. 0.77-0.95 U/L: Low Positive - M. pneumoniae-specific IgM presumptively detected. Collection of a follow-up sample in one to two weeks is recommended to assure reactivity. 0.96 U/L or greater: Positive - Highly significant amount of M. pneumoniae-specific IgM antibody detected. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. Reported: 1-3 days Mycoplasma pneumoniae DNA, Qualitative Real-Time PCR Order code: 39080 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction Unit code: 539080 CPT Code(s): 87581 Ref range: Negative Reported: 1-2 days Myelin Associated Glycoprotein (MAG) Antibody, IgM Order code: 82544 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Unacceptable: Heat-inactivated, hemolyzed, severely lipemic, or contaminated specimens. Urine. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 825440 CPT Code(s): 83516 Ref range: Less than 1000 TU Reported: 1-4 days Test List 10-318 S1 0 BBPL Directory of Services Myelin Basic Protein, CSF Order code: 84380 Preferred specimen: 1.0 mL CSF. Centrifuge CSF for 20 minutes and place the supernatant in a plastic transport tube. Ensure residual fibrin and cellular matter have been removed prior to transport. Minimum specimen: 0.4 mL CSF Unacceptable: Specimens other than CSF. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay (ELISA) Unit code: 827850 CPT Code(s): 83873 Ref range: 0.0-1.1 ng/mL Reported: 2-5 days Myelodysplastic Syndrome (MDS) Panel by FISH Order code: 80796 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 1 mL bone marrow or 2 mL whole blood Notes: Probes included: EGR1 (5q del), D7S486 (7q del/-7), CEP8 (+8), D20S108 (20q del) Other acceptable: 5.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807926 CPT Code(s): 88271 (x4), 88275 (x4), 88291 Ref range: By report Reported: Varies Myeloproliferative Disorders Panel by FISH S1 0 Order code: 80797 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL bone marrow or 2.0 mL whole blood Notes: Probes included: BCR/ABL, PDGFR-alpha, PDGFR-beta, FGFR1. Please submit a Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form. The information on this form is required to perform cytogenetic (chromosome) studies. Complete the form and submit with the test request form and specimen. Other acceptable: 10.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 807927 CPT Code(s): 88271 (x4), 88275 (x4), 88291 Ref range: By report Reported: Varies Myocardial Antibody, IgG with Reflex to Titer Order code: 80790 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.15 mL serum Notes: If Myocardial Antibody screen is 1:20, then a titer will be added at an additional charge. Unacceptable: Plasma. Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Indirect Fluorescent Antibody Unit code: 827950 CPT Code(s): 86255 Ref range: < 1:20 No antibody detection Reported: 1-4 days 10-319 Test List BBPL Directory of Services Myoglobin, Serum Order code: 84390 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Unacceptable: Gross hemolysis Transport temp: Refrigerated Method: Electrochemiluminescence Immunoassay Unit code: 828000 CPT Code(s): 83874 Ref range: Male: 28-72 ng/mL Female: 25-58 ng/mL Reported: 1-2 days Myoglobin, Urine Order code: 84400 Preferred specimen: 10.0 mL urine aliquot from a well-mixed random urine collection. Collect specimen in early morning or immediately following exercise. Minimum specimen: 1.0 mL urine Unacceptable: Gross hemolysis or plasma specimens. Transport temp: Frozen Method: Immunochemiluminometric Assay Unit code: 828050 CPT Code(s): 83874 Ref range: 0-5 ng/mL Reported: 1-3 days Myositis Antibody Panel Order code: 82806 Preferred specimen: 3.0 mL serum, red top tube or SST. Minimum specimen: 3.0 mL serum or plasma Notes: Test includes: MI-2, PL-7, PL-12, EJ, OJ, KU, SRP, U2 SNRNP Other acceptable: 3.0 mL plasma, lavender (EDTA) top tube. S1 0 Transport temp: Refrigerated Method: Immunoprecipitation Unit code: 828060 CPT Code(s): 83516 (x8) Ref range: Negative Reported: 7-14 days Mysoline See: Primidone N-Telopeptide, Cross-Linked (NTx), Serum Order code: 82839 Preferred specimen: 0.5 mL serum, red top tube. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 0.20 mL serum Unacceptable: Severely hemolyzed specimens. Transport temp: Frozen Method: Enzyme-Linked Immunosorbent Assay Unit code: 828839 CPT Code(s): 82523 Ref range: Adult Male: 5.4-24.2 nM BCE Premenopausal, Adult Female: 6.2-19.0 nM BCE The target value for treated postmenopausal adult females is the same as the premenopausal reference interval. BCE = Bone Collagen Equivalent Reported: 1-4 days NAPA, Serum See: Procainamide and N-Acetylprocainamide Test List 10-320 BBPL Directory of Services Naproxen Order code: 84405 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tube or gels. Transport temp: Refrigerated Method: High Performance Liquid Chromatography Unit code: 828100 CPT Code(s): 80299 Ref range: By report Reported: Varies Narcolepsy HLA-DQB1 06:02 Genotype Order code: 82813 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) or yellow (ACD A or B) top tube. Minimum specimen: 1.0 mL whole blood Transport temp: Refrigerated Method: Polymerase Chain Reaction/Fluorescence Monitoring Unit code: 828130 CPT Code(s): 81383 Ref range: By report Reported: Within 10 days Nasal Culture See: Culture, Nasopharyngeal Navane See: Thiothixene S1 0 Nebcin See: Tobramycin Neisseria gonorrhoeae & Chlamydia trachomatis DNA Panel See: Chlamydia trachomatis & Neisseria gonorrhoeae DNA Panel Neisseria gonorrhoeae Antibodies, Total Order code: 82851 Preferred specimen: 1.0 mL serum, SST. Minimum specimen: 0.15 mL serum Notes: Please label specimen as "Acute" or "Convalescent". Unacceptable: Plasma, icteric, lipemic, turbid, or contaminated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Complement Fixation Unit code: 828151 CPT Code(s): 86171 Ref range: Less than 1:8 Reported: 2-6 days 10-321 Test List BBPL Directory of Services Neisseria gonorrhoeae DNA Order code: 3161 Preferred specimen: APTIMA® vaginal swab, APTIMA® unisex swab (for endocervical and male urethral specimens), APTIMA® urine tube, or PreservCyt (ThinPrep) liquid Pap specimen, transport at room temperature or refrigerated. Aptima® swabs and Aptima® urine tubes may be frozen at -20°C to -70°C. Directions for specimen collection and handling are provided on the APTIMA® collection kits. APTIMA® kits are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Minimum specimen: One APTIMA® swab or tube. 1.0 mL ThinPrep or SurePath, 1.0 mL viral transport media, or 2.0 mL neat urine. Notes: Specimen Stability: APTIMA® swab specimens: 60 days at room temperature or refrigerated, 12 months frozen (-20°C to -70°C). Urine specimen in APTIMA® tube: 30 days at room temperature or refrigerated, 12 months frozen (-20°C to -70°C). Neat urine in collection cup: 24 hours at room temperature or refrigerated. Pap media specimen: Preservcyt, 30 days at room temperature or refrigerated; SurePath, 29 days at room temperature or refrigerated. Viral transport media: 2 days at room temperature, 3 days refrigerated. Other acceptable: SurePath liquid Pap specimen, endocervical/urethral swab in viral transport media or neat urine in sterile urine cup. Unacceptable: Probetec specimens, swabs in saline, specimens not within defined limits of stability. Transport temp: Room temperature Method: Nucleic Acid Amplification Test (NAAT) Unit code: 536002 CPT Code(s): 87591 Ref range: Negative Reported: 2-5 days Nembutal See: Pentobarbital Neoprofen See: Ibuprofen Neopterin Order code: 82818 Preferred specimen: 0.8 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic amber transport tube. Minimum specimen: 0.3 mL serum or plasma Notes: Protect from light during collection, storage, and shipping. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. Other acceptable: 0.8 mL plasma, lavender (EDTA) top tube. Remove plasma from cells and transfer to a plastic amber transport tube. Unacceptable: Specimens not protected from light. Room temperature or frozen specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 828180 CPT Code(s): 83520 Ref range: By report Reported: Within 9 days Neoral See: Cyclosporine A Neuramate See: Meprobamate Neurokinin A (Substance K) Order code: 82822 Preferred specimen: Collect blood in GI preservative tube (Z-tube). Remove plasma from cells within 1 hour of draw and transfer 5.0 mL plasma to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Contact BBPL Client Services for GI preservative tube (Z-tube) or order on BBPL web site. Minimum specimen: 1.0 mL plasma Notes: Patient must be fasting 10-12 hours prior to collection. Antacid medication or medications that may affect intestinal motility should be discontinued, if possible, for at least 48 hours prior to specimen collection. Unacceptable: Thawed specimens. Specimens not collected in Z-tube (GI preservative). Transport temp: CRITICAL FROZEN Method: Radioimmunoassay Unit code: 828220 CPT Code(s): 83519 Ref range: By report Reported: 4-21 days Test List 10-322 S1 0 BBPL Directory of Services Neuron Specific Enolase, CSF Order code: 82825 Preferred specimen: Collect CSF and transfer 0.5 mL to a plastic transport tube and freeze immediately. Minimum specimen: 0.5 mL CSF Transport temp: Frozen Method: Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 828255 CPT Code(s): 86316 Ref range: 1.0-7.0 µg/L Reported: 1-8 days Neuron-Specific Enolase Order code: 84425 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Unacceptable: Plasma. Hemolyzed specimens. Recently administered isotopes. Transport temp: Refrigerated Method: Radioimmunoassay (RIA) Unit code: 828250 CPT Code(s): 86316 Ref range: 0-12.5 ng/mL Reported: 1-4 days Neuronal Nuclear (Hu, Ri, and Yo) Antibodies IgG by Western Blot Order code: 82354 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.15 mL serum Notes: Antineuronal antibodies serve as markers that aid in discriminating between a true paraneoplastic neurological disorder (PND) and other inflammatory disorders of the nervous system. Anti-Hu (antineuronal nuclear antibody, type I) is associated with small-cell lung cancer. Anti-Ri (antineuronal nuclear antibody, type II) is associated with neuroblastoma in children and with fallopian tube and breast cancer in adults. Anti-Yo (anti-Purkinje cell cytoplasmic antibody) is associated with ovarian and breast cancer. Unacceptable: Plasma, contaminated, heat-inactivated, hemolyzed, or lipemic specimens. Transport temp: Refrigerated S1 0 Method: Western Blot Unit code: 828354 CPT Code(s): 83516 Ref range: None detected Reported: 1-8 days Neutrophil Associated Antibodies Order code: 84422 Preferred specimen: 3.0 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum Transport temp: Frozen Method: Flow Cytometry Unit code: 828400 CPT Code(s): 86021 Ref range: Negative Reported: 2-5 days Nexterone See: Amiodarone & Metabolite 10-323 Test List BBPL Directory of Services NHL FISH Profile Order code: 82445 Preferred specimen: 10.0 mL whole blood, green (sodium heparin) top tube or 2.0 mL bone marrow aspirate in a green (sodium heparin) top tube. Minimum specimen: 5.0 mL whole blood or 1.0 mL bone marrow Notes: For optimal results specimen must be received in laboratory within 24 hours of collection. If specimen collection time is greater than 24 hours, results may be reported with a disclaimer. Transport specimen on cold packs but do not place cold packs in direct contact with specimen. Other acceptable: Tissue (including lymph nodes, spleen) in RPMI media; Fluids 2-3 mL (ascitic, CSF) in sterile tube with equal volume RPMI media; Malignant fluids 50-100 mL in collection pouch; Formalin-fixed and paraffin-embedded tissue. Unacceptable: Clotted or frozen specimens. Paraffin-embedded tissue that has been decalcified. Transport temp: Refrigerated Method: The NHL Panel consists of 12 probes to chromosomes 3q27 (BCL6), 8q24 (MYC), 11q13 (CCND1), 14q32 (IgH) and 18q21 (BCL2) and 18q21 (MALT1). The IgH/CCND1 translocation is evaluated using a dual color, dual fusion translocation assay and the BCL6, MYC, IgH, BCL2 and MALT1 genes are evaluated using dual color break apart rearrangement assays. Unit code: 828445 CPT Code(s): 88367 (x12) Ref range: By report Reported: 3-10 days Niacin (Vitamin B3) Order code: 84155 Preferred specimen: 4.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells, transfer to a plastic amber transport tube and freeze. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. Protect from light during collection, storage, and shipping. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL plasma Unacceptable: Grossly hemolyzed or lipemic specimens. Thawed specimens or specimens not protected from light. Transport temp: CRITICAL FROZEN Method: High Performance Liquid Chromatography Unit code: 841555 CPT Code(s): 84591 Ref range: By report Reported: 5-11 days Nickel, Serum Order code: 84429 Preferred specimen: 2.0 mL serum, royal blue (no additive) top tube. Minimum specimen: 0.5 mL serum Notes: Remove serum from cells and place into a Trace Element-Free transport tube ASAP. Do not allow serum to remain on cells. Unacceptable: Separator tubes and specimens that are not separated from the red cells or clot within 6 hours. Transport temp: Room temperature Method: Inductively Coupled Plasma/Mass Spectrometry Unit code: 828470 CPT Code(s): 83885 Ref range: Less than or equal to 10.0 µg/L Reported: 1-8 days Nicotine See: Cotinine Screen, Serum or Plasma Nicotine and Metabolites, Serum or Plasma Nicotine and Metabolites, Urine Test List 10-324 S1 0 BBPL Directory of Services Nicotine and Metabolites, Serum or Plasma Order code: 82876 Preferred specimen: 4.0 mL serum, red top or gel-barrier tube. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 1.0 mL serum or plasma Notes: Drugs and analytes covered: Nicotine, Cotinine (metabolite), 3-OH-Cotinine (metabolite). Positive cutoff: 2 ng/mL The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory. For medical purposes only; not valid for forensic use. Other acceptable: 4.0 mL plasma, lavender (EDTA) or green (sodium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Plasma or whole blood from light blue (sodium citrate) top tube, specimens exposed to repeated freeze/thaw cycles. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 828476 CPT Code(s): 83887 Ref range: By report Reported: 1-4 days Nicotine and Metabolites, Urine Order code: 82847 Preferred specimen: 4.0 mL random urine with no additives or preservatives. Minimum specimen: 1.0 mL urine Notes: Drug and analytes covered: nicotine, cotinine (metabolite), 3-OH-cotinine (metabolite), nornicotine (metabolite),anabasine (tobacco biomarker). All drug and metabolites are the non-glucuronidated (free) form. Positive cutoff: Nicotine.................2 ng/mL Cotinine.................5 ng/mL 3-OH-Cotinine......50 ng/mL Nornicotine...........2 ng/mL Anabasine.............3 ng/mL The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory. Transport temp: Room temperature S1 0 Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 828475 CPT Code(s): 83887 Ref range: By report Reported: 1-4 days NMR LipoProfile Order code: 82861 Preferred specimen: Collect in NMR LipoTube (black-and-yellow top tube) or plain red top tube. Allow specimen to clot for 30 minutes before centrifugation. Specimen should be centrifuged within 24 hours of collection. Do not open NMR LipoTube. Ship spun NMR LipoTube to laboratory. If collected in a plain red top tube, pipette the separated serum (2.0 mL) into a plastic transport tube. Specimen must be kept refrigerated and shipped with cool packs within four days of draw. Do not freeze specimen and do not store at room temperature. Minimum specimen: 1.0 mL serum Notes: Patient should be fasting 12-14 hours. Unacceptable: Unspun LipoTube or unseparated plain red top tube, separator tubes or gels, gross hemolysis, EDTA plasma, frozen or room temperature specimens. Specimens more than 4 days old. Transport temp: Refrigerated Method: Nuclear magnetic resonance (NMR) Unit code: 828610 CPT Code(s): 80061, 83704 Ref range: By report Reported: 3-7 days Norclomipramine See: Clomipramine & Metabolite Normison See: Temazepam and Metabolite, Quantitative 10-325 Test List BBPL Directory of Services Norovirus Group 1 & 2 by RT-PCR Order code: 82873 Preferred specimen: 1.0 mL random stool (unpreserved) in a clean screw-capped container. Minimum specimen: 0.5 mL stool Transport temp: Frozen Method: Reverse-Transcription Polymerase Chain Reaction Unit code: 828730 CPT Code(s): 87798 (x2) Ref range: By report Reported: 5-7 days Norpace See: Disopyramide Norpramin See: Desipramine Nortriptyline Order code: 84470 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Notes: Do not order if amitriptyline is administered; instead order Amitriptyline & Nortriptyline by HPLC (order code 80550). Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 828750 CPT Code(s): 80182 Ref range: Therapeutic Range: 50-150 ng/mL Toxic: > 500 ng/mL S1 0 Reported: 1-5 days NPM1 Mutation by PCR and Fragment Analysis Order code: 82875 Preferred specimen: 5.0 mL whole blood, lavender top tube or 3.0 mL bone marrow (EDTA). Transport refrigerated. Or FFPE tumor tissue, formalin fix (10% neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Ship in cooled container during summer months. Transport tissue block or four 10-micron shavings at room temperature or refrigerated. Tissue block will be returned after testing. Tissue transport kits are available through BBPL Client Services for transporting tissue. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Record source on test request form. Testing includes pathologist's interpretation. Unacceptable: Frozen whole blood or bone marrow. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens. Transport temp: Whole blood or Bone marrow: Refrigerated. FFPE tumor tissue: Room temperature or refrigerated. Method: Polymerase Chain Reaction/Fragment Analysis Unit code: 828755 CPT Code(s): 81310, G0452 Ref range: By report Reported: 5-7 days Nuprin See: Ibuprofen Nurofen See: Ibuprofen Test List 10-326 BBPL Directory of Services Occult Blood (x1), Stool Order code: 2325 Preferred specimen: Stool submitted on occult card (Hemoccult), transport at room temperature. Minimum specimen: 1 gm stool specimen Notes: Patient should refrain from red meat and aspirin for 3 days prior to specimen collection. Specimen stability: Occult card, room temperature 14 days; stool specimen, refrigerated 72 hours. Other acceptable: Stool specimen (5 gm), transport refrigerated. Unacceptable: Frozen specimen or specimen in preservative, occult card other than Hemoccult. Transport temp: Occult card at room temperature or stool specimen refrigerated. Method: Guaiac Paper Test Unit code: 251100 CPT Code(s): 82270 Ref range: Negative Reported: Within 24 hours Occult Blood (x2), Stool Order code: 2326 Preferred specimen: 2 separate stool specimens submitted on occult cards (Hemoccult), transport at room temperature. Minimum specimen: 1 gm stool for each collection. Notes: Label each specimen with the patient's name and collection date and time. Patient should refrain from red meat and aspirin for 3 days prior to specimen collection. Specimen stability: Occult cards, room temperature 14 days; stool specimen, refrigerated 72 hours. Other acceptable: 2 separate stool specimens (5 gm each), transport refrigerated. Unacceptable: Frozen stool specimens or specimens in preservative, occult cards other than Hemoccult. Transport temp: Occult cards at room temperature or stool specimens refrigerated. Method: Guaiac Paper Test Unit code: 251110 CPT Code(s): 82270 Ref range: Negative Reported: Within 24 hours S1 0 Occult Blood (x3), Stool Order code: 2327 Preferred specimen: 3 separate stool specimens submitted on occult cards (Hemoccult), transport at room temperature. Minimum specimen: 1 gm stool for each collection. Notes: Label each specimen with the patient's name and collection date and time. Patient should refrain from red meat and aspirin for 3 days prior to specimen collection. Specimen stability: Occult cards, room temperature 14 days; stool specimen, refrigerated 72 hours. Other acceptable: 3 separate stool specimens (5 gm each), transport refrigerated. Unacceptable: Frozen stool specimens or specimens in preservative, occult cards other than Hemoccult. Transport temp: Occult cards at room temperature or stool specimens refrigerated. Method: Guaiac Paper Test Unit code: 251120 CPT Code(s): 82270 Ref range: Negative Reported: Within 24 hours Olanzapine Order code: 82887 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 1.0 mL serum or plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Timing of specimen collection: Pre-dose (trough) draw At steady state concentration. Other acceptable: 2.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Refrigerated or room temperature specimens. Transport temp: CRITICAL FROZEN Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 828875 CPT Code(s): 80299 Ref range: Therapeutic Range: 20-80 ng/mL Toxic: Not well established Reported: 1-5 days 10-327 Test List BBPL Directory of Services Oligoclonal Bands, CSF and Serum Order code: 82878 Preferred specimen: 0.5 mL CSF and 0.5 mL serum, red top tube or SST, collected at the same time (within 8 hours of each other). Minimum specimen: 0.1 mL CSF and 0.1 serum Unacceptable: Plasma. CSF and serum not collected within 8 hours of each other. Transport temp: Refrigerated Method: Isoelectric Focusing (IEF) and Immunoblotting on agarose gel Unit code: 828878 CPT Code(s): 83916 Ref range: None found; four or more CSF-specific bands have been shown to be most consistent with MS. Reported: 2-6 days Omca See: Fluphenazine Opiates Confirmation, Quantitative, Urine Order code: 82922 Preferred specimen: 20 mL random urine in a clean plastic urine container. Minimum specimen: 20 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Test includes: Codeine, Morphine, Hyromorphone, and Hydrocodone. Transport temp: Room temperature Method: Mass Spectrometry Unit code: 812922 CPT Code(s): 83925 Ref range: By report Reported: 3-7 days Opiates, Serum or Plasma S1 0 See: Drug Confirmation/Quantitation - Opiates, Serum or Plasma Orbinamon See: Thiothixene Organic Acids, Plasma Order code: 84497 Preferred specimen: 3.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells within 1 hour of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 2.0 mL frozen plasma Notes: Clinical information is needed for appropriate interpretation. Other required information includes age, gender, diet, drug therapy, and family history. A Patient History for Biochemical Genetic Testing for along with test request form must be submitted with specimen. The Organic Acids, Urine test is more sensitive than the Organic Acids, Plasma test. Therefore, urine is the preferred specimen to use when screening for inherited disorders of metabolism. Transport temp: CRITICAL FROZEN Method: Gas Chromatography/Mass Spectrometry Unit code: 829000 CPT Code(s): 83918 Ref range: By report Reported: 3-15 days Test List 10-328 BBPL Directory of Services Organic Acids, Urine Order code: 84480 Preferred specimen: 10 mL aliquot from a random urine collection. Freeze urine as soon as possible after collection. Avoid dilute urine when possible. Minimum specimen: 3 mL random urine Notes: Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. A Patient History for Biochemical Genetic Testing form along with test request form must be submitted with specimen. Certain analytes will be reported only if present at clinically significant concentrations (elevated). A special request for reporting of an analyte of interest may be recorded on the test request form or the Biochemical Genetics Patient History Form. Transport temp: CRITICAL FROZEN Method: Gas Chromatography/Mass Spectrometry Unit code: 828950 CPT Code(s): 83918 Ref range: By report Reported: 3-7 days Organism Identification with Reflex to Sensitivity Order code: 3200 Preferred specimen: Actively growing aerobic or anaerobic bacteria, yeast, or mold on appropriate agar slant. Note that suspected anaerobic organisms must be submitted in an anaerobic environment; such as a bag with an anaerobic gas generating pack. Notes: Include on the test request form the patient's name, physician, source of specimen, date specimen obtained, and date the agar was inoculated. Include any relevant information about the culture or organism, such as suspected pathogen, and previous identification results. Sensitivities will be performed on clinically significant aerobic bacteria isolates unless otherwise noted on the test request form. Additional charges apply for organism identification and susceptibility testing. Subculture should be maintained at submitting facility. Other acceptable: Organism growing on appropriate agar plate. Tape or otherwise seal plates securely shut. Unacceptable: Non-viable organisms. Frozen specimen. Suspected agents of bioterrorism, such as Francisella, Bacillus anthracis, Yersinia pestis, and Brucella must be sent to the client's State Public Health Laboratory. Transport temp: Room temperature Method: Identification and Sensitivity Methods Unit code: 402301 Reported: Within 3 days Organism Isolate Sensitivity Only S1 0 Order code: 3201 Preferred specimen: Actively growing aerobic or anaerobic bacteria, yeast, or mold on appropriate agar slant. Note that organism identification and specimen source are required to perform and provided accurate suspectibility testing. Identification will be performed by the laboratory if not provided on the test request form. Notes: Include on the test request form the patient's name, physician, source of specimen, date specimen collection, date the agar was inoculated, and organism identification. Additional charges apply for organism identification. Subculture should be maintained at submitting facility. Other acceptable: Organism growing on appropriate agar plate. Tape or otherwise seal plates securely shut. Unacceptable: Non-viable organisms. Frozen specimen. Suspected agents of bioterrorism, such as Francisella, Bacillus anthracis, Yersinia pestis, and Brucella. Transport temp: Room temperature Method: Sensitivity Methods Unit code: 402350 Reported: Within 3 days Organophosphate Pesticides Order code: 82912 Preferred specimen: 5.0 mL serum, red top tube or plasma, lavender (EDTA) top tube or gray (sodium fluoride) top tube. Do not collect in SST. Remove serum or plasma from cells within 2 hours of collection, transfer to a plastic transport tube and freeze. Minimum specimen: 2.2 mL serum or plasma Unacceptable: Separator tubes or gels. Transport temp: Frozen Method: High Performance Thin Layer Chromatography (HPTLC) Unit code: 829102 CPT Code(s): 82492 Ref range: By report Reported: 7-12 days Ormazine See: Chlorpromazine 10-329 Test List BBPL Directory of Services Osmolality, Fecal Order code: 84510 Preferred specimen: 5.0 mL aliquot of liquid stool in a clean unpreserved stool transport container, frozen. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL liquid stool Notes: Stool must be liquid. Do not add saline or water to liquefy sample. Unacceptable: Formed stools. Specimens in media or preservatives. Transport temp: CRITICAL FROZEN Method: Freezing Point Depression Unit code: 829200 CPT Code(s): 84999 Ref range: 0-16 years: 271-296 mOsm/kg 17 years and older: 280-303 mOsm/kg Reported: 1-2 days Osmolality, Serum or Plasma Order code: 84500 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 2.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Hemolyzed specimens. Transport temp: Refrigerated Method: Freezing Point Unit code: 829150 CPT Code(s): 83930 Ref range: Neonatal: may be as low as 266 mOsm/kg 0-60 years: 275-295 mOsm/kg 61 years and older: 280-301 mOsm/kg Reported: 1-3 days Osmolality, Urine Order code: 84520 Preferred specimen: 2.0 mL urine aliquot from a well-mixed random or 24-hour urine collection (no preservative). Refrigerate 24-hour specimen during collection. Record total volume for 24-hour collection on both the urine container and test request form. Minimum specimen: 0.2 mL urine Transport temp: Refrigerated Method: Freezing Point Unit code: 829250 CPT Code(s): 83935 Ref range: 24-hour urine: 300-900 mOsm/kg Random urine: 50-1400 mOsm/kg After 12-hour fluid restriction: >850 mOsm/kg Reported: 1-3 days Osmotic Fragility, Erythrocyte Order code: 84530 Preferred specimen: 5 mL whole blood, green (sodium or lithium heparin) or lavender (EDTA) top tube and a minimum of two unfixed, air-dried, and unstained smears to accompany the collected blood (smears should be made from the blood submitted). Specimens should be refrigerated within 30 minutes after collection. Minimum specimen: 1.0 mL whole blood and two unfixed smears. Notes: Send to laboratory on Sunday thru Thursday only. Do not send on Friday or Saturday. Samples must be received in laboratory within 48 hours of collection. Unacceptable: Grossly hemolyzed blood. Transport temp: Refrigerated Method: Spectrophotometry Unit code: 829300 CPT Code(s): 85555 Ref range: Within normal curve limits. For patients with acute hemolysis, a normal red cell osmotic fragility test result cannot exclude an osmotic fragility abnormality since the osmotically labile cells may be hemolyzed and not present. Recommend testing during a state of prolonged homeostasis with stable hematocrit. Reported: 1-5 days Test List 10-330 S1 0 BBPL Directory of Services Osteocalcin by Electrochemiluminescent Immunoassay Order code: 82845 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.3 mL serum or plasma. Other acceptable: 0.5 ml plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP and freeze. Unacceptable: Hemolyzed specimens. Transport temp: Frozen Method: Electrochemiluminescent Immunoassay Unit code: 828846 CPT Code(s): 83937 Ref range: Male: 6 months-6 years 39-121 ng/m 7-9 years 66-182 ng/mL 10-12 years 85-232 ng/mL 13-15 years 70-336 ng/mL 16-17 years 43-237 ng/mL 18 years and older 11-50 ng/mL Female: 6 months-6 years 44-130 ng/mL 7-9 years 73-206 ng/mL 10-12 years 77-262 ng/mL 13-15 years 33-222 ng/mL 16-17 years 24-99 ng/mL 18 years and older 11-50 ng/mL Reported: 1-4 days Ova and Parasites Exam, Stool Order code: 7140 Preferred specimen: Stool placed in O & P transport containers, inoculate both the formalin and PVA vial. Note: It is very important that BOTH formalin and PVA vials be inoculated with the stool specimen. Complete analysis is only possible when both vials of preservative are submitted for testing. Collect stool specimen in a clean, dry container. Immediately after collection, transfer the stool specimen to both the formalin and PVA vials, adding up to the fill line on each vial label. Mix vials well. Stool specimen preserved in O & P transport media is stable for 7 days stored at room temperature. If multiple stool specimens are indicated, collect on three separate days. Record the collection date and time on each specimen vial. Minimum specimen: 0.5 mL liquid stool or 1 g solid (pea-sized) stool. Notes: The ova and parasite exam does not test for the identification of Enterobius vermicularis (pinworm), refer to (order code 2345). Special stains are required for Cryptosporidium, Cyclospora, Isospora, or Microsporidia and are not detected by the ova and parasite exam. For Cryptosporidium, Cyclospora, and Isospora stains, refer to (order code 7400). Antigen testing by EIA is the preferred method for Cryptosporidium (order code 3469). For Microsporidia stain, refer to (order code 7410). S1 0 Other acceptable: Fresh stool specimen in a clean, plastic screw-cap container is acceptable only if the specimen will be received in the testing laboratory within 2 hours of collection. Transport refrigerated. Unacceptable: Specimens contaminated with barium or oil, specimens preserved in Cary Blair media or on swabs, frozen specimens, or multiple specimens (more than one in 24 hours) Transport temp: Room temperature Method: Microscopic Examination of Stool Concentrate and Trichrome Stain Unit code: 401910 CPT Code(s): 87177, 87209 Ref range: No parasites seen Reported: Within 3 days OVA1 Order code: 82939 Preferred specimen: 2.2 mL serum, SST. Allow blood to clot for 30 minutes but no longer than 2 hours. Centrifuge and transfer serum into a plastic transport tube. Please complete the billing information on the test request form and enclose a photo copy (front and back) of all relevant insurance cards. Include the menopausal status of the patient on the test request form. Minimum specimen: 1.1 mL serum Notes: Note: OVA1 Test is not to be used if patient is known to have rheumatoid factor of > or = 250 IU/L. Triglycerides above 450 mg/dL may interfere with the assay and should not be used. The test is not indicated for patients with diagnosis of malignancy within the last 5 years. Transport temp: Refrigerated Method: Electrochemiluminescence (ECLIA)/Fixed Rate Time Nephelometry Unit code: 829339 Ref range: By report Reported: 2-3 days 10-331 Test List BBPL Directory of Services Ovarian Malignancy Risk (ROMA) Order code: 83645 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.6 mL serum Notes: The Risk for Ovarian Malignancy Algorithm (ROMA®) is a qualitative serum test that combines the results of the Fujirebio HE4 EIA, Abbott Architect® CA 125 II, and menopausal status into a numerical score. ROMA is intended to aid in assessing whether there is a high or low likelihood of finding malignancy when surgery is performed on premenopausal or postmenopausal women who present with ovarian adnexal masses. Unacceptable: Grossly hemolyzed specimens. Transport temp: Refrigerated Method: Immunoassay and Calculation Unit code: 836345 CPT Code(s): 86849 Ref range: By report Reported: Within 5 days Oxactin See: Fluoxetine Oxalate, Urine Order code: 84540 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random collection. Refrigerate 24-hour specimen during collection. To properly aliquot specimen perform one of the two processing options: Option 1: a. Adjust pH to 1.5-3 with 6M HCl (approximately 10 mL HCl/24-hour specimen based on normal adult output of 1000-2000 mL/24 hours. Pediatric specimens will require less than 10 mL to reach correct pH). b. Transfer 4.0 mL aliquot of adjusted urine to a plastic urine container. Option 2: a. Transfer 4.0 mL aliquot from the well-mixed 24-hour urine collection to a plastic urine container with 20 mg Sulfamic Acid. b. Record total volume and collection time on both the urine container and test request form. The information is required for test interpretation. Minimum specimen: 1.5 mL urine aliquot Notes: Patient should avoid ingestion of vitamin C prior to specimen collection. Unacceptable: Specimens with no preservative or with a pH greater than 4. Transport temp: Refrigerated S1 0 Method: Quantitative Spectrophotometry Unit code: 829350 CPT Code(s): 83945 Ref range: 0-12 years: 13-38 mg/d Male 13 years and older: 7-44 mg/d Female 13 years and older: 4-31 mg/d Reported: 1-4 days Oxazepam See: Temazepam and Metabolite, Quantitative Oxcarbazepine Metabolite Order code: 82905 Preferred specimen: 1.0 mL serum, red top tube. DO NOT draw in SST. Remove serum from cells ASAP. Minimum specimen: 0.4 mL serum or plasma Notes: Draw trough levels immediately prior to next dose. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Separator tubes or gels. Gross lipemia, hemolysis, and icteric specimens. Transport temp: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Unit code: 829025 CPT Code(s): 80183 Ref range: 10-35 µg/mL Reported: 1-3 days Oxycodone See: Drug Confirmation, Quantitation Opiates, Serum or Plasma Test List 10-332 BBPL Directory of Services Oxycodone/Oxymorphone Confirmation, Quantitative, Urine Order code: 81274 Preferred specimen: 20 mL random urine in a clean plastic urine container. Minimum specimen: 10 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Transport temp: Room temperature Method: Liquid Chromatography/Tandem Mass Spectrometry (LC/MS-MS) Unit code: 812740 CPT Code(s): 83925 Ref range: By report Reported: 5-7 days p57 Immunohistochemistry Order code: 35110 Preferred specimen: Formalin-fixed, paraffin-embedded (FFPE) tissue. For multiple specimens, submit a separate test request form with each specimen. Minimum specimen: Three pre-cut tissue slldes. Other acceptable: Three pre-cut tissue slides. Transport temp: Room temperature Method: Immunohistochemistry Unit code: 535110 CPT Code(s): 88342 Ref range: By report Reported: 3-7 days Pacerone See: Amiodarone & Metabolite Pamelor S1 0 See: Nortriptyline by HPLC Pancreastatin Order code: 82944 Preferred specimen: Collect blood in GI preservative tube (Z-tube). Remove plasma from cells within 1 hour of draw and transfer 2.0 mL plasma to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Contact BBPL Client Services for GI preservative tube (Z-tube) or order on BBPL web site. Minimum specimen: 1.0 mL plasma Notes: Patient must be fasting 10-12 hours prior to collection. Patient should not be on any medications that may influence insulin levels, if possible, for at least 48 hours prior to collection. Unacceptable: Thawed specimens. Specimens not collected in Z-tube (GI preservative). Transport temp: CRITICAL FROZEN Method: Radioimmunoassay Unit code: 829440 CPT Code(s): 83519 Ref range: By report Reported: 5-22 days Pancreatic Elastase, Fecal Order code: 82948 Preferred specimen: 5 gm random formed stool in a clean unpreserved stool transport container. Freeze immediately. Minimum specimen: 1 gm stool Notes: Patient Prep: Interruption of enzyme substitution therapy recommended in order to avoid the possibility of cross-reaction with porcine enzymes. Unacceptable: Samples ambient longer than four hours. Stool in media or preservative. Transport temp: Frozen Method: Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 829448 CPT Code(s): 83520 Ref range: Normal: 201 µg/g or greater Moderate to mild exocrine pancreatic insufficiency: 100-200 µg/g Severe exocrine pancreatic insufficiency: 99 µg/g or less Reported: 1-4 days 10-333 Test List BBPL Directory of Services Pancreatic Polypeptide Order code: 84550 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow specimen to sit in collection tube for 15-20 minutes at room temperature for proper clot formation. Centrifuge and remove serum from cells ASAP or within 2 hours of collection. Transfer serum to a plastic transport tube and freeze. Minimum specimen: 0.5 mL serum Notes: Patient should be fasting for 10 hours prior to collection of specimen. Unacceptable: Plasma, severely hemolyzed or lipemic specimens. Transport temp: Frozen Method: Radioimmunoassay Unit code: 829500 CPT Code(s): 83519 Ref range: 0-435 pg/mL Reported: 3-11 days Parainfluenza Virus (Types 1-4) RNA, Qualitative Real-Time PCR Order code: 39026 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Notes: Test includes Parainfluenza Virus types 1, 2, 3, and 4. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction Unit code: 539026 CPT Code(s): 87631 Ref range: Negative Reported: 1-2 days Parainfluenza Virus Antibody by CF Order code: 82947 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Notes: Complement fixation testing for this virus group (Parainfluenza 1, 2, 3) is somewhat less sensitive than HI or neutralizaiton testing. Unacceptable: Hemolzyed, lipemic, or grossly contaminated specimens. Transport temp: Refrigerated Method: Complement Fixation (CF) Unit code: 829547 CPT Code(s): 86710 (x3) Ref range: Less than 1:8 Reported: 3-5 days Paraneoplastic Antibodies (PCCA/ANNA) by IFA with Reflex to Titer and Western Blot Order code: 82833 Preferred specimen: 2.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.75 mL serum Unacceptable: Contaminated, heat-inactivated, hemolyzed, or lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Western Blot Unit code: 828330 CPT Code(s): 86255 Ref range: Purkinje Cell/Neuronal Nuclear IgG Screen: None Detected Neuronal Nuclear Antibody (ANNA) IFA Titer, IgG: Less than 1:10 Purkinje Cell Antibody, Titer: Less than 1:10 Neuronal Nuclear (Hu, Ri, and Yo) Antibodies IgG by Western Blot: None Detected Reported: 1-9 days Test List 10-334 S1 0 BBPL Directory of Services Parasite Identification Gross Examination Order code: 3815 Preferred specimen: Parasite immersed in enough saline to cover specimen, submitted in a clean plastic screw-capped container. Minimum specimen: Must be enough specimen to visually see in the container. Other acceptable: Parasite in formalin or in a clean plastic screw-capped container. Unacceptable: Specimens taped or mashed on a glass slide. Transport temp: Room temperature Method: Macroscopic and/or Microscopic Examination Unit code: 401915 CPT Code(s): 87169 Reported: 1-3 days Parathyroid Hormone Plus Minerals Order code: 94066 Preferred specimen: 2.5 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. Minimum specimen: 1.5 mL serum Notes: Test Includes: Parathyroid Hormone, Intact with Calcium Creatinine, Serum Phosphorus, Inorganic, Serum Transport temp: Frozen Method: Chemiluminescent Immunoassay/Colorimetric/Kinetic Unit code: 94066 CPT Code(s): 82310, 82565, 83970, 84100 Ref range: Intact PTH: 14-72 pg/mL Calcium: 8.5-10.5 mg/dL Creatinine: 0.4-1.5 mg/dL Phosphorus, Inorganic: 2.5-4.8 mg/dL Reported: Within 24 hours Parathyroid Hormone, Intact with Calcium Order code: 1042 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells, transfer to a plastic transport tube and freeze. S1 0 Minimum specimen: 1.0 mL serum Transport temp: Frozen Method: Chemiluminescent Immunoassay and Colorimetric Unit code: 104200 CPT Code(s): 82310, 83970 Ref range: Intact PTH: 14-72 pg/mL Calcium: 8.5-10.5 mg/dL Reported: Within 24 hours Parathyroid Hormone-Related Peptide Order code: 83353 Preferred specimen: Collect 3.0 mL whole blood using protease inhibitor tube available through BBPL Client Services or online using BBPL Electronic Supply Order Form. A winged collection set must be used. NOT RECOMMENDED: Filling collection tubes directly through a needle/tube-holder assembly increases the risk of chemical reflux back into the vein of the patient. WARNING: Collection tubes are NOT STERILE. Mix collection tube thoroughly. Centrifuge and remove plasma from cells within 1 hour of collection. Transfer 1.5 mL plasma to a plastic transport tube and freeze immediately. Do not submit the collection tube for testing. Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Grossly hemolyzed specimens. Transport temp: Frozen Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 833502 Ref range: Male: 0.0-2.3 pmol/L Female: 0.0-3.4 pmol/L Reported: 2-6 days 10-335 Test List BBPL Directory of Services Parietal Cell Antibody, IgG Order code: 80800 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.25 mL serum Unacceptable: Urine or plasma. Contaminated, heat-inactivated, grossly hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 829650 CPT Code(s): 83516 Ref range: Negative: 0.0-20.0 Units Equivocal: 20.1-24.9 Units Positive: 25.0 Units or greater Reported: 1-3 days Paroxetine, Serum or Plasma Order code: 82966 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.4 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 829660 CPT Code(s): 80299 Ref range: By report Reported: Varies Paroxysmal Nocturnal Hemoglobinuria, High Sensitivity, RBC Order code: 82965 Preferred specimen: 4.0 mL whole blood, lavender (EDTA) or green (sodium or lithium heparin) top tube. Specimens must be received in laboratory within 3 days of collection. Minimum specimen: 0.5 mL whole blood Unacceptable: Bone marrow, clotted, hemolyzed, or frozen specimens. Specimens not received in laboratory within 3 days of collection. Transport temp: Refrigerated Method: Quantitative Flow Cytometry Unit code: 829665 CPT Code(s): 86356 (x2) Ref range: By report This assay tests for CD59 on erythrocytes using flow cytometry. The percentage of red blood cells (RBCs) with normal expression of CD59 is decreased in paroxysmal nocturnal hemoglobinuria (PNH). The presence of a subclinical (0.005 percent-0.999 percent) PNH population in myelodysplastic bone marrow disorders such as aplastic anemia or refractory anemia may correlate with a positive immunotherapeutic response. (Blood 2006; 107, 1308-1314). The lower limit of detection of this test is 0.005 percent PNH cells and distinguishes between Type II and Type III cells when the PNH cell percentage is 1 percent or greater. Glycophorin A is used to gate the RBC population. CD59 is the GPI-linked antigen. Recent RBC transfusions may decrease the percentage of PNH cells. (Cytometry 42:223-33, 2000). Reported: 1-4 days Paroxysmal Nocturnal Hemoglobinuria, WBC Order code: 82967 Preferred specimen: 4.0 mL whole blood, lavender (EDTA) or green (sodium or lithium heparin) top tube. Specimens must be received in laboratory within 2 days of collection. Minimum specimen: 4.0 mL whole blood Unacceptable: Bone marrow, clotted, hemolyzed, or frozen specimens. Specimens not received in laboratory within 2 days of collection. Transport temp: Refrigerated Method: Quantitative Flow Cytometry Unit code: 829667 CPT Code(s): 86356 (x5) Ref range: By report This test was developed according to recently published guidelines (Cytometry B Clin Cytom. 2010 Jul; 78 (4):211-30),and includes diagnostic WBC analysis using FLAER, CD14, and CD24 as GPI-linked markers with CD15 and CD33 as lineage-specific markers. The lower limit of detection for this test is 0.1 percent PNH cells and is the most accurate measurement of the PNH clone size used to assist with therapeutic decisions in conventional PNH. For delineation of RBC populations Types II and III when the PNH clone is 1 percent or greater, Paroxysmal Nocturnal Hemoglobinuria, High Sensitivity, RBC (ARUP test code 2004366) is available. This test also detects minor (0.005-0.999 percent) PNH clone populations found in bone marrow failure disorders. Reported: 1-4 days Test List 10-336 S1 0 BBPL Directory of Services Partial Thromboplastin Time See: PTT Partial Thromboplastin Time (PTT) Order code: 2390 Preferred specimen: One full unopened light blue top tube (3.2% sodium citrate). Light blue top tube must be completely filled to ensure proper blood to anticoagulant ratio (9:1). Mix tube by gentle inversion 3-6 times immediately after collection. Do not uncap tube. If obtaining specimen with a butterfly, draw a waste tube first and discard. Minimum specimen: 90% filled light blue top tube (3.2% sodium citrate) or 0.5 ml plasma. Other acceptable: NON-HEPARINZED PATIENTS: Do not centrifuge. Do not remove top from tube. Send unopened tube same day. IF PATIENT IS HEPARINZED: Centrifuge specimen within one hour of collection. Transfer top half of plasma to plastic transport tube and FREEZE immediately. Transport specimen FROZEN. Unacceptable: Gross hemolysis, clotted specimen, improper blood to citrate ratio, specimen collected in tube other than 3.2% citrate. Transport temp: Room temperature for light blue top tube. Send unopened tube to lab within 24 hours. Frozen for plasma. Method: Photo Optical Clot Detection Unit code: 202360 CPT Code(s): 85730 Ref range: 28.0-40.0 seconds Reported: Within 24 hours Partial Thromboplastin Time Mixing Study Order code: 84953 Preferred specimen: 2.0 mL frozen citrated (3.2% sodium citrate) plasma from a light blue top tube. Mix the light blue top tube by gentle inversion 10-12 times immediately after drawing. A completely filled blue top tube is required because the ratio of blood to citrate is critical (9:1). Centrifuge and transfer the top half of plasma to a plastic transport tube and freeze immediately. Minimum specimen: 1.5 mL plasma Unacceptable: Serum. Non-frozen or hemolyzed plasma. Transport temp: FROZEN Method: Mixing Study Unit code: 833251 CPT Code(s): 85730, 85732 (x2) Ref range: By report Reported: Within 24 hours S1 0 Parvovirus B-19 Antibodies, IgG & IgM Order code: 84600 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.3 mL serum or plasma Notes: Remove serum or plasma from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Other acceptable: 0.5 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Heat-inactivated, hemolyzed, hyperlipemic, icteric, or contaminated serum specimens. Transport temp: Refrigerated Method: Enzyme Linked Immunosorbent Assay Unit code: 829700 CPT Code(s): 86747 (x2) Ref range: Parvovirus B 19 Antibody, IgG: 0.89 IV or less: Negative - No significant level of detectable Parvovirus B19 IgG antibody. 0.90-1.10 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgG antibody to Parvovirus B19 detected, which may indicate a current or past infection. Parvovirus B 19 Antibody, IgM: 0.89 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody. 0.90-1.10 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. Reported: 1-3 days 10-337 Test List BBPL Directory of Services Parvovirus B-19 Antibody, IgG Order code: 82971 Preferred specimen: 0.5 ml serum, red top tube or SST. Minimum specimen: 0.3 mL serum or plasma Notes: Remove serum or plasma from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Other acceptable: 0.5 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Heat-inactivated, hyperlipemic, icteric, hemolyzed, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 829701 CPT Code(s): 86747 Ref range: 0.89 IV or less: Negative - No significant level of detectable Parvovirus B19 IgG antibody. 0.90-1.10 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgG antibody to Parvovirus B19 detected, which may indicate a current or past infection. Reported: 1-3 days Parvovirus B-19 Antibody, IgM Order code: 82972 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.3 mL serum or plasma Notes: Remove serum or plasma from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Other acceptable: 0.5 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Heat-inactivated, hyperlipemic, icteric, hemolyzed, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay Unit code: 829702 CPT Code(s): 86747 Ref range: 0.89 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody. 0.90-1.10 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. Reported: 1-3 days Parvovirus B-19, PCR Order code: 82699 Preferred specimen: 1.0 mL serum, red top tube or SST or 1.0 mL plasma, lavender (EDTA) top tube. Remove serum or plasma from cells, transfer to a plastic transport tube and freeze. Or 1.0 mL amniotic fluid, CSF, or synovial fluid in sterile container frozen. Minimum specimen: 0.5 mL serum, plasma, CSF, amniotic or synovial fluid. Notes: Specimen source is required. Other acceptable: Fresh tissue transferred to a sterile container and frozen immediately or formalin fixed and paraffin embedded tissue at room temperature. Tissue transport kits are available through BBPL Client Services for transporting tissue. Unacceptable: Heparinized specimens. Bone marrow. Transport temp: Frozen; except for paraffin embedded tissue at room temperature. Method: Qualitative Polymerase Chain Reaction Unit code: 829699 CPT Code(s): 87798 Ref range: By report Reported: 1-4 days PBG, Urine See: Porphobilinogen Test List 10-338 S1 0 BBPL Directory of Services PCA3 (Prostate Cancer Gene 3) Order code: 35130 Preferred specimen: First voided urine following DRE exam. Collect according to the PCA3 Urine Specimen Transport kit instructions. Immediately after collection transfer 2.5 mL urine to the specimen transport tube using the disposable pipette provided in the kit. PCA3 urine collection kit and instructions are available through BBPL Client Services or online using the BBPL Electronic Supply Order Form. Minimum specimen: 2.5 mL post-DRE urine Unacceptable: Specimens not received in PCA3 collection kits. Less than 2.5 mL urine in the specimen transport tube. Specimen received at room temperature. Transport temp: Frozen Method: Transcription Mediated Amplification (TMA) and Hybridization Protection Assay (HPA) Unit code: 535130 CPT Code(s): 81479 Reported: Within 7 days PCB See: Polychlorinated Biphenyls Screen with Reflex to Confirmation Peganone See: Ethotoin Pemphigoid Panel-Epithelial Basement Membrane Zone Antibodies, IgG & IgA, BP180 & BP230 Antibodies, IgG Order code: 82989 Preferred specimen: 2.0 mL serum, red top or gel-barrier tube. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Please submit Immunodermatology Required Clinical Information Form (Serum) with test request form and specimen. Unacceptable: Hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Indirect Immunofluorescence Unit code: 829899 CPT Code(s): 83516 (x2), 88347 (x4) S1 0 Ref range: By report Reported: 4-9 days Pentobarbital Order code: 84670 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Separator tubes, light blue (citrate), or yellow (SPS or ACD solution). Transport temp: Refrigerated Method: Quantitative Gas Chromatography-Mass Spectrometry Unit code: 830150 CPT Code(s): 82205 Ref range: Therapeutic Range: Sedation: 1-5 µg/mL Intracranial Pressure (ICP) Therapy: 23-35 µg/mL Coma: 10-50 µg/mL Toxic Level: Greater than 10 µg/mL Reported: 1-5 days PEP See: Protein Electrophoresis, CSF Protein Electrophoresis, Serum Protein Electrophoresis, Urine Permitil See: Fluphenazine 10-339 Test List BBPL Directory of Services Perphenazine Order code: 84680 Preferred specimen: 2.0 mL serum, red top tube. Remove serum from cells within 6 hours of collection, transfer to a plastic amber transport tube. Protect from light. Do not collect in SST. Minimum specimen: 1.0 mL serum or plasma Notes: SST or PST: Serum or plasma in a gel separator tube stored at room temperature is acceptable if separated from the gel within 6 hours. Serum or plasma in a gel separator tube stored refrigerated is acceptable if separated from the gel within 2 hours. Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 2.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 6 hours of collection, transfer to a plastic amber transport tube. Protect from light. Unacceptable: Citrated plasma or tubes that contain liquid anticoagulant. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 830250 CPT Code(s): 84022 Ref range: Therapeutic Range: 0.6-2.4 ng/mL Toxic: Greater than 12 ng/mL Reported: 1-3 days Pethidine See: Meperidine and Metabolite pH, 24-Hour Urine Order code: 1027 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour urine collection. Refrigerate 24-hour specimen during collection period. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 2.0 mL urine aliquot Unacceptable: Any specimen other than a 24-hour urine collection. Transport temp: Refrigerated Method: pH Electrode Unit code: 102478 CPT Code(s): 83986 Ref range: 5.0-8.0 S1 0 Reported: Within 24 hours pH, Body Fluid Order code: 1327 Preferred specimen: 4.0 mL body fluid. Mix fluid well and transfer aliquot into a plastic transport tube or sterile urine cup. Freeze. Minimum specimen: 2.0 mL fluid Notes: Indicate source on test request form. Unacceptable: Highly viscous specimens. Transport temp: Frozen Method: pH Electrode Unit code: 103270 CPT Code(s): 83986 Ref range: None established Reported: Within 24 hours pH, Fecal See: Fecal pH Phencyclidine Confirmation, Quantitative, Urine Order code: 82926 Preferred specimen: 15 mL random urine in a clean plastic urine container. Minimum specimen: 7 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 812926 CPT Code(s): 83992 Ref range: By report Reported: 3-5 days Test List 10-340 BBPL Directory of Services Phencyclidine, Serum or Plasma See: Drugs of Abuse Confirmation/Quantitation - Phencyclidine, Serum or Plasma Phenobarbital Order code: 1190 Preferred specimen: 0.5 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 0.5 mL plasma, green (sodium or lithium heparin) or lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 110060 CPT Code(s): 80184 Ref range: Therapeutic: 15-40 µg/mL Potentially Toxic: >60 µg/mL Reported: Within 24 hours Phenol Exposure, Urine Order code: 83415 Preferred specimen: 4.0 mL random urine, no preservative. Minimum specimen: 1.9 mL urine Notes: For industrial exposure: collect urine at end of work shift. Unacceptable: Urine specimens with benzoic acid. Transport temp: Refrigerated Method: Gas Chromatography/Colorimetry Unit code: 830415 CPT Code(s): 82570, 84600 Ref range: By report Reported: Varies S1 0 Phenolphthalein, Fecal Preferred specimen: 5 gm aliquot of stool in a clean unpreserved stool container. Freeze specimen immediately and ship to laboratory frozen within 24 hours. Minimum specimen: 1 gm stool. Notes: Separate specimens must be submitted when multiple tests are ordered. Nonfrozen specimens may produce false-negative results. Unacceptable: Samples in preservative. Transport temp: CRITICAL FROZEN Method: Colorimetry Unit code: 830420 Ref range: Negative Reported: Within 24 hours Phenylalanine & Tyrosine, Plasma Order code: 84710 Preferred specimen: 0.5 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection. Transfer plasma to a plastic transport and freeze. Minimum specimen: 0.25 mL plasma Notes: This test is designed to monitor treatment and compliance in PKU patients. Unacceptable: Hemolyzed specimens. Transport temp: Frozen Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 830500 CPT Code(s): 82131, 84510 Ref range: Phenylalanine Monitoring, Plasma: <30 days: 30-100 µmol/L 1-11 months: 30-90 µmol/L 1 year and older: 30-80 µmol/L Tyrosine, Plasma: 0-11 months: 30-140 µmol/L 1 year and older: 30-120 µmol/L Reported: 2-5 days 10-341 Test List BBPL Directory of Services Phenylalanine Monitoring, Plasma Order code: 83051 Preferred specimen: 0.5 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection. Transfer plasma to a plastic transport tube and freeze. Minimum specimen: 0.25 mL plasma or serum Notes: This test is designed to monitor treatment and compliance in PKU patients. Other acceptable: 0.5 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Unacceptable: Hemolyzed specimens. Transport temp: Frozen Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 830501 CPT Code(s): 82131 Ref range: 0-30 days: 30-100 µmol/L 1-11 months: 30-90 µmol/L 1 year and older: 30-80 µmol/L Reported: 2-5 days Phenytoin Order code: 1185 Preferred specimen: 0.5 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 0.2 mL serum or plasma Other acceptable: 0.5 mL plasma, green (sodium or lithium heparin) or lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 110070 CPT Code(s): 80185 Ref range: Therapeutic: 10-20 µg/mL Potentially Toxic: >40 µg/mL Reported: Within 24 hours Phenytoin, Free Order code: 1189 Preferred specimen: 2.0 mL serum, red top tube or SST. Red top tube: Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Separator tube (SST): Centrifuge within 2 hours of collection and transport SST refrigerated within 48 hours or transfer serum to a plastic transport tube. Minimum specimen: 1.0 mL serum or plasma Other acceptable: 2.0 mL plasma, green top tube (sodium or lithium heparin). Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Immunoassay Unit code: 110072 CPT Code(s): 80186 Ref range: Therapeutic: 1.0-2.0 mcg/mL Potentially toxic: >3.0 mcg/mL Reported: Within 24 hours Phosphate, Inorganic, Serum Order code: 1365 Preferred specimen: 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Colorimetric Unit code: 101680 CPT Code(s): 84100 Ref range: 2.5-4.8 mg/dL Reported: Within 24 hours Test List 10-342 S1 0 BBPL Directory of Services Phosphatidylcholine Antibodies, IgG, IgA, IgM Order code: 80331 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum Unacceptable: Plasma or body fluids. Heat-inactivated, hemolyzed, icteric, or contaminated serum. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 803310 CPT Code(s): 83516 (x3) Ref range: By report Reported: Within 8 days Phosphatidylserine Antibodies, IgG, IgM, IgA Order code: 80336 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Unacceptable: Gross hemolysis, bacterial contamination, lipemia. Transport temp: Refrigerated Method: Enzyme-linked Immunosorbent Assay Unit code: 803360 CPT Code(s): 86148 (x3) Ref range: By report Reported: 1-8 days Phospholipid Antibodies, IgG, IgM See: Cardiolipin Antibodies, IgG, IgM Phospholipid Antibodies, IgG, IgM, IgA See: Cardiolipin Antibodies, IgG, IgM, IgA S1 0 Phospholipid Antibody, IgA See: Cardiolipin Antibody, IgA Phospholipid Antibody, IgG See: Cardiolipin Antibody, IgG Phospholipid Antibody, IgM See: Cardiolipin Antibody, IgM Phospholipids Order code: 84714 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Transport temp: Refrigerated Method: Spectrophotometry Unit code: 830650 CPT Code(s): 84311 Ref range: 160-300 mg/dL Reported: 1-2 days Phosphorus, Serum See: Phosphorus, Inorganic, Serum 10-343 Test List BBPL Directory of Services Phosphorus, Urine Order code: 1505 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Transport temp: Refrigerated Method: Colorimetric Unit code: 102480 CPT Code(s): 84105 Ref range: Excretion: 400-1300 mg/day Reported: Within 24 hours Pinworm Identification See: Enterobius Vermicularis Plac Test See: Lipoprotein-Associated Phospholipase A2 Plasminogen Activator Inhibitor 1, Activity Order code: 83085 Preferred specimen: 1.5 mL platelet-poor plasma, light blue (sodium citrate) top tube. Centrifuge and remove plasma from cells, and freeze plasma within 1 hour of collection. Collect specimen between 8 a.m. and 12 p.m. Minimum specimen: 1.0 mL plasma Notes: Separate specimens must be submitted when multiple tests are ordered. Unacceptable: Serum. Hemolyzed specimens. Specimens that have been thawed and refrozen. Transport temp: CRITICAL FROZEN. Method: Bioimmunoassay Unit code: 830855 CPT Code(s): 85415 Ref range: By report S1 0 Reported: 1-8 days Plasminogen Activity Order code: 84740 Preferred specimen: 1.0 mL platelet-poor plasma, light blue (sodium citrate) top tube. Remove platelet-poor plasma from cells and transfer to a plastic transport tube. Freeze immediately. Separate specimens must be sumitted when multiple tests are ordered. Minimum specimen: 0.5 mL plasma Unacceptable: Serum, EDTA plasma, nonfrozen or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Chromogenic Assay Unit code: 830850 CPT Code(s): 85420 Ref range: 71-144% Reported: 1-4 days Plasmodium Species PCR Reflex Order code: 80911 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) or yellow (ACD-A) top tube. Minimum specimen: 0.5 mL whole blood Notes: Supplemental testing may be added at an additional charge to identify Plasmodium species (i.e. P. falciparum, P. knowlesi, P. malariae, P. ovale, and P. vivax). Unacceptable: Frozen blood, heparin tube, or gross specimen contamination. Transport temp: Refrigerated Method: Real-time Polymerase Chain Reaction Unit code: 830911 CPT Code(s): 87799 Reported: 2-5 days Test List 10-344 BBPL Directory of Services Platelet Antibodies, Indirect Order code: 84780 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and freeze. For newborns less than 30 days old, collect specimen from the mother. Minimum specimen: 0.5 mL serum or plasma Notes: This is the primary test for detection of platelet-specific antibodies. It is not recommended for the diagnosis of immune thrombocytopenic purpura (ITP). This test will detect both allo and autoantibodies, but will not distinguish between them. This test is designed to detect antibodies to platelet glycoproteins IIb/IIIa (HPA-1a/1b [PlA1 and PlA2], HPA-3a/3b, and HPA-4a), Ia/IIA (HPA-5a/5b), Ib/IX, and IV. In addition, this test will also detect antibodies to HLA Class I antigens (HLA-A-B). Testing for neonatal alloimmune thrombocytopenia should be performed using a maternal serum, since platelet antibody may not be detected in a neonatal serum. False negative results are common in infant samples. Other acceptable: 1.0 mL plasma, lavender (EDTA) or yellow (ACD Solution A) top tube. Remove plasma from cells ASAP or within 2 hours of collection, transfer to a plastic transport tube and freeze. Unacceptable: Microbially contaminated, hemolyzed, lipemic, or heat-inactivated specimens. Transport temp: Frozen Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 831300 CPT Code(s): 86022 Ref range: None detected Reported: 1-3 days Platelet Associated Antibodies (IgG/IgM), Direct Assay Order code: 84798 Preferred specimen: 10.0 mL whole blood, lavender (EDTA) top tube. Specimen must be received in laboratory within 24 hours after collection. Minimum specimen: 5.0 mL EDTA whole blood Unacceptable: Clotted, hemolyzed, frozen, or refrigerated specimens. Specimens older tha 48 hours. Transport temp: CRITICAL ROOM TEMPERATURE Method: Flow Cytometry Unit code: 831050 CPT Code(s): 86023 (x2) Ref range: IgG: Negative; IgM: Negative Negative (IgG & IgM): No excess antibodies were associated with the patient's platelets. An immune cause of thrombocytopenia is unlikely. Positive (IgG and/or IgM): An increase in platelet associated immunoglobulin is noted. An immune cause of thrombocytopenia should be considered. However, many conditions can result in an increase in platelet associated antibodies; for example, IgM rheumatoid factor antibodies. Strong Positive (IgG and/or IgM): A definite increase in platelet associated immunoglobulin is noted and an immune cause of thrombocytopenia should be considered. However, many conditions can result in an increase in platelet associated antibodies; for example, IgM rheumatoid factor antibodies. S1 0 Note: Detection of platelet-associated IgG and/or IgM may be used to separate thrombocytopenia of immune origin from nonimmune origin. Most patients with ITP have abnormally high levels of IgG associated with their platelets. Occasionally patients will have normal IgG levels but abnormally high levels of IgM. Dual staining and flow cytometric analysis ensures that only platelets are analyzed and relatively small volumes of blood are required. This assay does not distinguish between autoantibodies and alloantibodies, nor does it identify specific types of antiplatelet antibodies, such as those against HPA-1a. Reported: 2-3 days Platelet Count, Automated Order code: 2355 Preferred specimen: One 3-4 mL lavender (EDTA) top tube. Refrigerate EDTA tube if specimen will not be received in laboratory within 24 hours of collection. Stability: Room temperature 24 hours, refrigerated 48 hours. Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Other acceptable: If platelet clumping is a problem, submit both EDTA and sodium citrate (blue top) tubes. Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Refrigerated Method: Automated Hematology Analyzer Unit code: 201120 CPT Code(s): 85049 Ref range: Male/Female: 130-400 thou/cumm Reported: Within 24 hours 10-345 Test List BBPL Directory of Services PM/Scl-100 Antibody, IgG with Reflex to ANA IFA Order code: 87475 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.3 mL serum Notes: If PM/Scl-100 is greater than or equal to 11 Units, then Anti-Nuclear Antibody (ANA) by IFA, IgG will be added at an additional charge. Unacceptable: Plasma. Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Immunoblot/Immunofluorescence Antibody Unit code: 837476 CPT Code(s): 86235 Ref range: Less than 11 Units Reported: 1-9 days PML-RARA Translocation, t(15;17) by PCR, Quantitative Order code: 83130 Preferred specimen: 5.0 mL whole blood, lavender (EDTA) top tube or 3.0 mL bone marrow (EDTA). TIME SENSITIVE: Specimens must be received in laboratory same day as collected. Minimum specimen: 1.0 mL whole blood or bone marrow Notes: Testing includes pathologist's interpretation. Unacceptable: Specimens collected in anticoagulants other than EDTA. Serum, frozen specimens, clotted or severely hemolyzed specimens. Transport temp: Refrigerated Method: Reverse Transcription Polymerase Chain Reaction Unit code: 831531 CPT Code(s): 81315, G0452 Ref range: By report Reported: 2-7 days PML/RARA Translocation by FISH Order code: 83133 Preferred specimen: 3.0 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin) top tube. TIME SENSITIVE. Specimen must be received in laboratory within 24 hours of collection. Minimum specimen: 1.0 mL bone marrow or 2.0 mL whole blood Other acceptable: 10.0 mL whole blood, green (sodium heparin) top tube. Other specimen types may be acceptable, contact BBPL Client Services for specific specimen collection and transportation instructions. Unacceptable: Frozen, clotted, or paraffin-embedded specimens. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 831533 CPT Code(s): 88271, 88275, 88291 Ref range: By report Reported: 1-3 days Test List 10-346 S1 0 BBPL Directory of Services Pneumococcal Antibodies, IgG (14 serotypes) Order code: 84837 Preferred specimen: 1.5 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection and transfer to a plastic transport tube. Post-immunization specimen should be drawn 30 days after immunization and, if shipped separately, must be received within 60 days of pre-immunization specimen. Mark specimens clearly as "Pre" or "Post" so specimens will be saved and tested simultaneously. Minimum specimen: 0.25 mL serum Notes: Includes: Serotypes 1, 3, 4*, 5, 6B*, 7F, 8, 9N, 9V*, 12F, 14*, 18C*, 19F*, 23F* All serotypes tested are present in the 23-valent pure polysaccharide pneumococcal vaccine. The serotypes marked with an asterisk are contained in the conjugated pneumococcal vaccine. Unacceptable: Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Quantitative Multiplex Bead Assay Unit code: 831650 CPT Code(s): 86317 (x14) Ref range: A pre-and post-vaccination sample comparison is required in order to assess the humoral immune response to vaccination with Streptococcus pneumoniae vaccine. Post vaccination samples should be obtained at 4 weeks post-immunization. A single sample provides only general immune status of an individual to various serotypes of pneumococci. Immune response to pneumococci may vary in different individuals based on age, vaccination status, immunologic competence and the serotype of the organism. Longterm protection is generally considered to be a serotype antibody level of 1.3 µg/ mL or greater. Following vaccination, an antibody ratio of less than twofold is considered a non-responder; a ratio of two-to fourfold is a weak responder; a ratio of fourfold or greater is a good responder. The higher the pre-vaccination antibody level for a specific pneumococcal serotype, the less likely the response will increase significantly after vaccination. An increased antibody level to 50-70 percent or more of the serotypes is thought to represent a normal humoral response. In the case of pure polysaccharide vaccine, indication of immune system competence is further delineated as an adequate response to at least 70 percent of the serotypes in the vaccine challenge for those 6-65 years of age, or to at least 50 percent of the serotypes in the vaccine challenge for those 2-5 years of age Reported: 1-2 days Pneumocystis jiroveci DFA Order code: 83166 Preferred specimen: Bronchial washing, induced sputum, or bronchoalveolar lavage in sterile container. Transport 5.0 mL respiratory specimen in sterile container. Minimum specimen: 0.5 mL Unacceptable: Tissues, slides, or swabs. Formalinized or frozen specimens. S1 0 Transport temp: Refrigerated Method: Direct Fluorescent Antibody Stain Unit code: 831660 CPT Code(s): 87281 Ref range: Negative Reported: Within 24 hours Pneumonitis, Hypersensitivity See: Hypersensitivity Pneumonitis PNH RBC See: Paroxysmal Nocturnal Hemoglobinuria Profile-RBC Poliovirus Antibodies Order code: 84840 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum or CSF Other acceptable: 1.0 mL CSF Unacceptable: Plasma, contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Serum Neutralization Unit code: 831750 CPT Code(s): 86658 (x3) Ref range: Less than 1:10: No detectable poliovirus antibodies. 1:10 or greater: Antibody to poliovirus detected, which may represent prior immunization or current or past infection. The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against other types. Reported: 6-9 days 10-347 Test List BBPL Directory of Services Polychlorinated Biphenyls Screen with Reflex to Confirmation Order code: 83182 Preferred specimen: 3.0 mL serum, red top tube. Remove serum from cells within 45 minutes of collection and transfer to a plastic transport tube. Minimum specimen: 3.0 mL serum Notes: If initial testing indicates, confirmation testing will be added at an additional charge. Other acceptable: 3.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 45 minutes of collection and transfer to a plastic transport tube. Transport temp: Refrigerated Method: Gas ChromatographyMass Spectrometry Unit code: 831802 CPT Code(s): 82441 Ref range: By report Reported: 5-7 days Porphobilinogen (PBG) Deaminase, Erythrocyte Order code: 83189 Preferred specimen: 3.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.0 mL whole blood Unacceptable: Body fluid other than EDTA preserved whole blood. Clotted specimens. Transport temp: Frozen Method: Quantitative Enzymatic/Fluorometry Unit code: 831890 CPT Code(s): 82657 Ref range: Adult: 2.10-4.30 mU/g Hb Reported: 1-5 days Porphobilinogen, Urine Order code: 84850 Preferred specimen: 8.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Protect from light during collection, storage, and shipping. Refrigerate 24-hour specimen during collection. Transfer urine aliquot into plastic amber transport tubes and freeze. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. Record total volume and collection time on transport tube and test request form. Minimum specimen: 3.5 mL urine aliquot S1 0 Unacceptable: Body fluids other than urine. Transport temp: Frozen Method: Ion Exchange Chromatography/Spectrophotometry Unit code: 831900 CPT Code(s): 84110 Ref range: Porphobilinogen, Urine: 0.0-8.8 µmol/L Porphobilinogen, Urine (24-hour): 0.0-11.0 µmol/d Reported: 1-4 days Porphyrins, Fecal Order code: 84890 Preferred specimen: 5 gm random stool in a clean unpreserved stool transport container. Freeze immediately after collection. Wrap stool container completely in aluminum foil ASAP to protect from light. Critical to protect from light during collection, storage, and shipping. Minimum specimen: 2 gm random stool, frozen Unacceptable: Complete timed collections (24-72 hour) or liquid stool. Transport temp: CRITICAL FROZEN Method: High Performance Liquid Chromatography Unit code: 832050 CPT Code(s): 84126 Ref range: Coproporphyrin: 0-45 nmol/g dry weight Protoporphyrin: 0-100 nmol/g dry weight Reported: 2-7 days Test List 10-348 BBPL Directory of Services Porphyrins, Fractionation and Quantitation, Urine Order code: 84900 Preferred specimen: 4.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Protect from light during collection, storage, and shipping. Refrigerate 24-hour specimen during collection. Transfer urine aliquot into a plastic amber transport tube and freeze. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. Record the total volume and hours of collection on the transport tube and the test request form. Minimum specimen: 2.0 mL urine Unacceptable: Body fluids other than urine. Transport temp: Frozen Method: High Performance Liquid Chromatography Unit code: 832200 CPT Code(s): 84120 Ref range: By report Reported: 1-5 days Porphyrins, Total with Reflex to Fractionation, Plasma Order code: 83999 Preferred specimen: 3.0 mL plasma, green (sodium heparin) or lavender (EDTA) top tube. Remove plasma from cells, transfer to a plastic amber transport tube and freeze immediately. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. CRITICAL: Protect from light during collection, storage, and shipping. Separate specimens must be submitted when multiple tests are ordered. Patient should abstain from alcohol for 24 hours prior to collection. Include a current list of patient's medications with the specimen. Minimum specimen: 1.0 mL plasma Notes: If total porphyrins are greater than 1.0 then fractionation will be performed at an additional charge. Unacceptable: Separator tubes or gels. Specimens not protected from light. Thawed specimens. Transport temp: CRITICAL FROZEN Method: Qualitative Extraction and Scanning Spectrofluorometry / Quantitative High Performance Liquid Chromatography Unit code: 831999 CPT Code(s): 84311 Ref range: By report Reported: 3-5 days S1 0 Porphyrins, Total, Plasma or Serum Order code: 83199 Preferred specimen: 2.0 mL plasma, green (sodium or lithium heparin) or lavender (EDTA) or serum, red top tube. Remove plasma or serum from cells, transfer to a plastic amber transport tube and freeze. If amber tubes are not available wrap transport tube with aluminum foil to protect from light. CRITICAL: Protect from light during collection, storage, and shipping. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL plasma or serum Notes: Useful for evaluation of cutaneous photosensitivity to rule out porphyrin disorders, particularly erythropoietic protoporphyria. The best specimen for evaluation of suspected porphyria cutanea tarda (PCT) is a urine specimen. Continued monitoring of PCT with serum is an acceptable practice. Evaluation of neurologic and/or psychiatric symptoms associated with suspected acute porphyria (such as acute intermittent porphyria) requires Porphobilinogen (PBG), Urine (order code 84850). Protoporphyrin is extremely light sensitive, whereas uroporphyrin and coproporphyrin are much less so. Specimens from patients with suspected erythropoietic protoporphyria should be carefully protected from exposure to light. Unacceptable: Hemolyzed specimen. Frozen whole blood. Specimens other than plasma or serum. Transport temp: Frozen Method: Quantitative Fluorometry Unit code: 831990 CPT Code(s): 84311 Ref range: 0-15 nmol/L Reported: 1-5 days Potassium, Fecal Order code: 80799 Preferred specimen: 5 gm liquid random stool in a clean unpreserved stool transport container. Minimum specimen: 1 gm stool Notes: Stool must be liquid. Do not add saline or water to liquefy specimen. Unacceptable: Formed or viscous stool. Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 807399 CPT Code(s): 84999 Ref range: Not established Reported: 2-3 days 10-349 Test List BBPL Directory of Services Potassium, Serum Order code: 1030 Preferred specimen: 1.0 mL serum, SST or red top tube. Remove serum from cells ASAP, avoid hemolysis. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 101630 CPT Code(s): 84132 Ref range: 3.5-5.0 mmol/L Reported: Within 24 hours Potassium, Urine Order code: 1052 Preferred specimen: 5.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 1.0 mL urine aliquot Transport temp: Refrigerated Method: Ion-Selective Electrode Unit code: 102467 CPT Code(s): 84133 Ref range: 25-125 mmol/day Reported: Within 24 hours Potiga See: Ezogabine and Metabolite Poxi See: Librium & Nordiazepam S1 0 PR3/MPO See: Anit-Neutrophil Cytoplasmic Antibodies Prealbumin Order code: 1427 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens. Transport temp: Refrigerated Method: Nephelometry Unit code: 112650 CPT Code(s): 84134 Ref range: 18-45 mg/dL Reported: 1-2 days Pregabalin (Lyrica) Order code: 82255 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 0.4 mL serum or plasma Notes: Remove serum or plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Unacceptable: Serum separator tubes or gels. Transport temp: Refrigerated Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 832255 CPT Code(s): 80299 Ref range: By report Reported: Varies Test List 10-350 BBPL Directory of Services Pregnenolone by LC-MS/MS, Serum or Plasma Order code: 82355 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP or within 2 hours of collection. Aliquot 0.5 mL serum into two plastic transport tubes and freeze immediately. Minimum specimen: 0.25 mL serum or plasma per tube Notes: Separate specimens must be submitted when multiple tests are ordered. Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP or within 2 hours of collection. Aliquot 0.5 mL plasma into two plastic transport tubes and freeze immediately. Unacceptable: Refrigerated or room temperature specimens. Transport temp: CRITICAL FROZEN Method: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry Unit code: 832355 CPT Code(s): 84140 Ref range: By report Reported: 1-4 days Prenatal Basic Panel Order code: 15397 Preferred specimen: 2.0 mL serum, red top or SST and 2 lavender (EDTA) top tubes, 5.0 mL whole blood each. See individual tests for additional handling requirements. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 1.5 mL serum and 4.0 mL whole blood in each EDTA tube Notes: Test includes: ABO Group and Rh Type Antibody Screen Hepatitis B Surface Antigen RPR Rubella Antibody IgG CBC with Automated Differential Transport temp: Refrigerated Method: See individual tests. Unit code: 96000 CPT Code(s): 80055 Ref range: See individual tests. Reported: 1-3 days S1 0 Prenatal Basic Panel Plus HIV Order code: 96002 Preferred specimen: 2.5 mL serum, red top or SST and 2 lavender (EDTA) top tubes, 5.0 mL whole blood each. See individual tests for additional handling requirements. If additional tests other than Blood Bank are ordered, requiring a lavender top tube (EDTA), a separate tube should be collected for these tests. Minimum specimen: 2.0 mL serum and 4.0 mL whole blood in each EDTA tube Notes: Test includes: ABO Group and Rh Type Antibody Screen Hepatitis B Surface Antigen HIV-1/2 Antibodies, EIA RPR Rubella Antibody, IgG CBC with Automated Differential Transport temp: Refrigerated Method: See individual tests. Unit code: 96002 CPT Code(s): 80055, 86703 Ref range: See individual tests. Reported: 1-3 days Primidone Order code: 1225 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.8 mL serum or plasma Notes: Test includes Primidone and Phenobarbital. Collect specimen immediately prior to next dose. Other acceptable: 1.0 mL plasma, green (sodium heparin) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels, severely hemolyzed, lipemic or icteric specimens. Transport temp: Refrigerated Method: Immunoassay Unit code: 832370 CPT Code(s): 80184, 80188 Ref range: Primidone: 5.0-12.0 µg/mL Phenobarbital: 15.0-40.0 µg/mL Reported: Within 24 hours 10-351 Test List BBPL Directory of Services Pro-Predict Metabolite See: Thiopurine Metabolites Procainamide and N-Acetylprocainamide (NAPA) Order code: 84930 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum or plasma Notes: Collection times: Oral treatment: peak: 75 minutes after dose; trough: immediately before next dose. I.V. treatment: immediately after loading dose; 2, 6, 12, and 24 hours after starting I.V. maintenance. Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells ASAP and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels, severely hemolyzed, lipemic, or icteric specimens. Transport temp: Refrigerated Method: Immunoassay Unit code: 832450 CPT Code(s): 80192 Ref range: Procainamide: 4.0-10.0 µg/mL Procainamide + NAPA : 10.0-30.0 µg/mL Reported: 1-2 days Procalcitonin Order code: 83246 Preferred specimen: 2.0 mL plasma, green (lithium heparin) top tube. Remove plasma from cells, transfer to a plastic transport tube and freeze. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.6 mL plasma Unacceptable: Avoid freeze thaw cycles. Transport temp: Frozen Method: Enzyme Immunoassay Unit code: 832460 CPT Code(s): 84145 Ref range: <0.05 ng/mL S1 0 Reported: Within 24 hours Procollagen Type I Intact N-Terminal Propeptide Order code: 83470 Preferred specimen: 0.5 mL serum, red top tube or SST. Allow serum tube to sit 15-20 minutes at room temperature for proper clot formation. Centrifuge and remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Collect all specimens at the same time of day; there is a diurnal variation of PINP and values are higher at night. Minimum specimen: 0.2 mL serum Unacceptable: Plasma. Hemolyzed or lipemic specimens. Transport temp: Refrigerated Method: Quantitative Radioimmunoassay Unit code: 832470 CPT Code(s): 83519 Ref range: Reference Interval: Males: 22-105 µg/L Females: Premenopausal: 20-101 µg/L Postmenopausal: 16-96 µg/L Reported: 1-8 days Test List 10-352 BBPL Directory of Services Progesterone, Serum Order code: 1289 Preferred specimen: 1.0 mL serum, SST or red top tube Minimum specimen: 0.5 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111106 CPT Code(s): 84144 Ref range: Males: 0.3-1.2 ng/mL Females: Follicular phase: 0.2-1.4 ng/mL Luteal phase: 3.3-25.6 ng/mL Mid Luteal phase: 4.4-28.0 ng/mL Post menopausal: <0.7 ng/mL Pregnancy: 1st Trimester: 11.2-90.0 ng/mL 2nd Trimester: 25.6-89.4 ng/mL 3rd Trimester: 48.4-422.5 ng/mL Reported: Within 24 hours Prograf See: Tacrolimus (FK506) Proinsulin Order code: 84945 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP, transfer to a plastic transport tube and freeze. Minimum specimen: 0.6 mL serum Notes: Patient must be fasting 12-15 hours before collection. Please submit separate frozen specimens when multiple tests are ordered. Unacceptable: Plasma, nonfrozen specimens, grossly hemolyzed or lipemic specimens. Transport temp: CRITICAL FROZEN Method: Enzyme Immunoassay Unit code: 832400 CPT Code(s): 84206 S1 0 Ref range: 0.0-9.4 pmol/L Reported: 2-6 days Prolactin, Serum Order code: 1285 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.3 mL serum Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111110 CPT Code(s): 84146 Ref range: Males: 2.1-17.7 ng/mL Females: Nonpregnant: 2.8-29.2 ng/mL Pregnant: 9.7-208.5 ng/mL Post Menopausal: 1.8-20.3 ng/mL Reported: Within 24 hours Prolixin See: Fluphenazine Pronestyl See: Procainamide and N-Acetylprocainamide (NAPA) 10-353 Test List BBPL Directory of Services Propafenone Order code: 84951 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 832650 CPT Code(s): 80299 Ref range: Therapeutic Range: 0.50-2.00 µg/mL Toxic Level: > 2.00 µg/mL Reported: 1-5 days Propoxyphene & Metabolite, Serum or Plasma See: Drugs of Abuse Confirmation/Quantitation - Propoxyphene & Metabolite, Serum or Plasma Propoxyphene Confirmation, Quantitative, Urine Order code: 81746 Preferred specimen: 20 mL random urine in a clean plastic urine container. Minimum specimen: 15 mL urine Notes: Order only for clinical or medical purposes; not for forensic use or pre-employment screen or random employee testing. No chain of custody form required. Transport temp: Room temperature Method: Gas Chromatography/Mass Spectrometry (GS/MS) Unit code: 812746 CPT Code(s): 83925 Ref range: By report Reported: 5-7 days Propranolol Order code: 83540 Preferred specimen: 2.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Trough levels are most reproducible. Other acceptable: 2.0 mL plasma, green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels. Transport temp: Refrigerated Method: High-pressure liquid chromatography with fluorescence detection (HPLC/FL) Unit code: 832700 CPT Code(s): 82491 Reported: Within 7 days Prostaglandin E2, Urine Order code: 83274 Preferred specimen: 10.0 mL urine aliquot from a well-mixed 24-hour urine collection. Refrigerate during collection. No preservative required. Freeze urine aliquot immediately after final collection is complete. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 5.0 mL urine aliquot Notes: Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen. Transport temp: Frozen Method: Radioimmunoassay Unit code: 832740 CPT Code(s): 84150 Ref range: By report Reported: Within 14 days Prostate Specific Antigen, Free See: Prostate Specific Antigen, Total and Free Test List 10-354 S1 0 BBPL Directory of Services Prostate Specific Antigen, PSA Order code: 1282 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Notes: Appropriate for serial monitoring. Unacceptable: Room temperature specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111130 CPT Code(s): 84153 Ref range: 0-4.0 ng/mL Reported: Within 24 hours Prostate Specific Antigen, PSA-Annual Screen Order code: 1281 Preferred specimen: 0.5 mL serum, red top tube or SST. Minimum specimen: 0.2 mL serum Notes: Appropriate for annual screening purposes. Unacceptable: Room temperature specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111132 CPT Code(s): 84153 Ref range: 0-4.0 ng/mL Reported: Within 24 hours Prostate Specific Antigen, Total and Free Order code: 1283 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.5 mL serum Notes: Test includes PSA-Free, PSA-Total, and PSA-Percent Free. Unacceptable: Serum refrigerated longer than 48 hours or room temperature specimens. Grossly hemolyzed specimens. S1 0 Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 111127 CPT Code(s): 84153, 84154 Ref range: By report Reported: 1-3 days Prostate Specific Antigen, Ultrasensitive Order code: 1279 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow specimen to clot completely at room temperature. Remove serum from cells within 2 hours of collection, transfer to a plastic transport tube and refrigerate. Minimum specimen: 0.5 mL serum Notes: Specimens should be collected before biopsy, prostatectomy, prostatic massage or digital rectal exam since these may lead to elevated PSA levels for up to 3 weeks. Unacceptable: Grossly hemolyzed or grossly lipemic specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 111135 CPT Code(s): 84153 Ref range: 0-4.00 ng/mL Reported: 1-3 days 10-355 Test List BBPL Directory of Services Prostatic Acid Phosphatase Order code: 1280 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow specimen to clot completely at room temperature before centrifuging. Remove serum from cells, transfer to a plastic transport tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 0.5 mL serum Notes: Specimen should be obtained before rectal examination, biopsy, prostatectomy or prostatic massage, since manipulation of the prostate gland may lead to elevated PAP levels persisting up to 24-48 hours. Unacceptable: Specimens ambient greater than 3 hours or refrigerated greater than 24 hours. Transport temp: Frozen Method: Chemiluminescent Immunoassay Unit code: 832751 CPT Code(s): 84150 Ref range: 0.0-3.5 ng/mL Reported: Within 24 hours Protein C & S Panel, Total Antigen Order code: 83060 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube filled to completion to ensure proper blood to anticoagulant ratio. Mix tube by gentle inversion at least six times. Centrifuge and immediately remove only the top two-thirds of the platelet-poor plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a plastic transport tube and FREEZE immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Preferred tests for detection of protein C and S deficiencies are Protein C Functional (84975) and Protein S Free Antigen (83310 ). Do not order if individual has been on warfarin therapy in the previous 2-4 weeks. Unacceptable: Serum, nonfrozen, or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Microlatex Particle-Mediated Immunoassay Unit code: 833060 CPT Code(s): 85302, 85305 Ref range: Protein C, Total Antigen 1-4 days: 17-53% 5-29 days: 20-64% 30-89 days: 21-65% 90-179 days: 28-80% 180-364 days: 37-81% 1-5 years: 40-92% 6-10 years: 45-93% 11 years and older: 63-153% S1 0 Protein S, Total Antigen 1-4 days: 12-60% 5-29 days: 22-78% 30-89 days: 33-93% 90-179 days: 54-118% 180-364 days: 55-119% 1-5 years: 54-118% 6-10 years: 41-114% 11 years and older: Females: 63-126%; Males: 84-134% Reported: 1-2 days Protein C, Activity See: Protein C, Functional Test List 10-356 BBPL Directory of Services Protein C, Functional Order code: 84975 Preferred specimen: 1.5 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube filled to completion to ensure proper blood to anticoagulant ratio. Mix tube by gentle inversion at least six times. Centrifuge and immediately remove only the top two-thirds of the platelet-poor plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a plastic transport tube and FREEZE immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Patients on oral anticoagulants may have decreased functional protein C values. Patients should be off oral anticoagulant therapy for two weeks for accurate measurement of functional protein C levels. Artificially increased functional protein C values may be due to heparin therapy or the presence of direct thrombin inhibitors. Unacceptable: Serum, nonfrozen, or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 832900 CPT Code(s): 85303 Ref range: 1-4 days: 17-53% 5-29 days: 20-64% 30-89 days: 21-65% 90-179 days: 28-80% 180-364 days: 37-81% 1-6 years: 40-92% 7-9 years: 70-142% 10-11 years: 68-143% 12-13 years: 66-162% 14-15 years: 69-170% 16-17 years: 70-171% 18 years and older: 83-168% Reported: 1-2 days Protein C, Total Antigen Order code: 84970 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube filled to completion to ensure proper blood to anticoagulant ratio. Mix tube by gentle inversion at least six times. Centrifuge and immediately remove only the top two-thirds of the platelet-poor plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a plastic transport tube and FREEZE immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Not recommended for detecting protein C deficiency; preferred test is Protein C, Functional (84975). Use Protein C Total Antigen to subtype deficiency in known protein C-deficient individuals. Do not order if individual has been on warfarin therapy in the previous 2-4 weeks. Patients on oral anticoagulants may have decreased protein C values. S1 0 Unacceptable: Serum, nonfrozen, or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Enzyme Immunoassay Unit code: 832850 CPT Code(s): 85302 Ref range: 1-4 days: 17-53% 5-29 days: 20-64% 30-89 days: 21-65% 90-179 days: 28-80% 180-364 days: 37-81% 1-5 years: 40-92% 6-10 years: 45-93% 11 years and older: 63-153% Reported: 1-2 days Protein Electrophoresis, CSF with Reflex to Immunofixation Electrophoresis Order code: 1545 Preferred specimen: 5.0 mL CSF in a sterile tube Minimum specimen: 2.5 mL CSF Notes: If required after pathologist review the protein electrophoresis will reflex to Immunofixation Electrophoresis, a more sensitive method for identification of small M-proteins, at an additional charge. Unacceptable: Hemolysis may interfere. Transport temp: Refrigerated Method: Electrophoresis, Colorimetry Unit code: 113020 CPT Code(s): 84157, 84166 Ref range: Total protein: 15-45 mg/dL Pre-Albumin: 0.8-6.7% Albumin: 58.4-91.3% Alpha-1: 0.9-6.7% Alpha-2: 0.8-5.6% Beta: 2.1-15.5% Gamma: 1.0-11.2% Reported: 1-3 days 10-357 Test List BBPL Directory of Services Protein Electrophoresis, Serum with Reflex to Immunofixation Electrophoresis Order code: 1540 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Notes: If required after pathologist review the protein electrophoresis will reflex to Immunofixation Electrophoresis, a more sensitive method for identification of small M-proteins, at an additional charge. Transport temp: Refrigerated Method: Electrophoresis, Colorimetry Unit code: 113004 CPT Code(s): 84155, 84165 Ref range: Total protein: 6.0-8.5 g/dL Albumin: 3.22-5.10 g/dL Alpha-1: 0.08-0.38 g/dL Alpha-2: 0.35-1.15 g/dL Beta: 0.38-1.24 g/dL Gamma: 0.44-1.52 g/dL Reported: 1-3 days Protein Electrophoresis, Urine with Reflex to Immunofixation Electrophoresis Order code: 1550 Preferred specimen: 25.0 mL urine aliquot from a well mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. Do not add preservatives or transport in urine preservative tubes. Record the total volume and hours of collection on both the specimen container and the test request form. Minimum specimen: 5.0 mL urine aliquot Notes: If required after pathologist review the protein electrophoresis will reflex to Immunofixation Electrophoresis, a more sensitive method for identification of small M-proteins, at an additional charge. Unacceptable: Urine with preservatives. Transport temp: Refrigerated Method: Electrophoresis, Colorimetry Unit code: 113040 CPT Code(s): 84156, 84166 Ref range: Total Protein: 0-150 mg/24 hrs, Trace of albumin. Reported: 1-3 days Protein S Free, Antigen Order code: 83310 Preferred specimen: 1.5 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube filled to completion to ensure proper blood to anticoagulant ratio. Mix tube by gentle inversion at least six times. Centrifuge and immediately remove only the top two-thirds of the platelet-poor plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a plastic transport tube and FREEZE immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Recommended test to detect protein S deficiency. Do not order if individual has been on warfarin therapy in the previous 2-4 weeks. Patients on oral anticoagulants will have decreased free protein S values. Patients should be off oral anticoagulant therapy for two weeks for accurate measurement of free protein S levels. Decreased levels of free protein S are also associated with DIC, liver disease, pregnancy, and inflammatory syndromes. Unacceptable: Serum, nonfrozen, or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Microlatex Particle-Mediated Immunoassay Unit code: 833001 CPT Code(s): 85306 Ref range: 1-89 days: 15-55% 90-179 days: 35-92% 180-364 days: 45-115% 1-5 years: 62-120% 6-9 years: 62-130% 10-17 years: 60-140% 18 years and older Male: 74-147% 18 years and older Female: 55-123% Reported: 1-3 days Protein S, Activity See: Protein S, Functional Test List 10-358 S1 0 BBPL Directory of Services Protein S, Functional Order code: 84985 Preferred specimen: 2.0 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube filled to completion to ensure proper blood to anticoagulant ratio. Mix tube by gentle inversion at least six times. Centrifuge and immediately remove only the top two-thirds of the platelet-poor plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a plastic transport tube and FREEZE immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Patients on oral anticoagulants may have decreased functional protein S values. Patients should be off oral anticoagulant therapy for two weeks for accurate measurement of protein S. Artificially increased functional protein S values may be due to heparin therapy or the presence of direct thrombin inhibitors. Unacceptable: Serum, nonfrozen, or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Clotting Unit code: 833000 CPT Code(s): 85306 Ref range: Male: 1-89 days: 15-55% 90-179 days: 35-92% 180-364 days: 45-115% 1-5 years: 62-120% 6 years: 62-130% 7-9 years: 66-140% 10-11 years: 65-139% 12-13 years: 72-139% 14-15 years: 68-145% 16-17 years: 77-167% 18 years and older: 66-143% Female: 1-89 days: 15-55% 90-179 days: 35-92% 180-364 days: 45-115% 1-5 years: 62-120% 6 years: 62-130% 7-9 years: 62-151% 10-11 years: 65-142% 12-13 years: 70-140% 14-15 years: 55-145% 16-17 years: 51-147% 18 years and older: 57-131% Reported: 1-2 days S1 0 Protein S, Total Antigen Order code: 84980 Preferred specimen: 1.5 mL platelet-poor plasma, light blue (3.2% sodium citrate) top tube filled to completion to ensure proper blood to anticoagulant ratio. Mix tube by gentle inversion at least six times. Centrifuge and immediately remove only the top two-thirds of the platelet-poor plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a plastic transport tube and FREEZE immediately. Separate specimens must be submitted when multiple tests are ordered. Minimum specimen: 1.0 mL platelet-poor plasma Notes: Not recommended for detecting protein S deficiency; preferred test is Protein S Free, Antigen (83310). Use Protein S Total to subtype deficiency in known protein S-deficient individuals in combination with Protein S Free, Antigen, or Protein S, Functional (84985). Do not order if individual has been on warfarin therapy in the previous 2-4 weeks. Patients on oral anticoagulants may have decreased protein S values. Unacceptable: Serum, nonfrozen, or hemolyzed specimens. Transport temp: CRITICAL FROZEN Method: Microlatex Particle-Mediated Immunoassay Unit code: 832950 CPT Code(s): 85305 Ref range: 1-4 days: 12-60% 5-29 days: 22-78% 30-89 days: 33-93% 90-179 days: 54-118% 180-364 days: 55-119% 1-5 years: 54-118% 6-10 years: 41-114% 11 years and older: Females: 63-126%; Males: 84-134% Reported: Within 2 days Protein, Total, CSF Order code: 1527 Preferred specimen: 1.0 mL CSF Minimum specimen: 0.1 mL CSF Unacceptable: Gross hemolysis may cause falsely elevated results. Transport temp: Refrigerated Method: Pyrogallol Red Unit code: 103220 CPT Code(s): 84157 Ref range: 15-45 mg/dL Reported: Within 24 hours 10-359 Test List BBPL Directory of Services Protein, Total, Fluid Order code: 1530 Preferred specimen: 1.0 mL body fluid in a plastic transport tube. Minimum specimen: 0.5 mL fluid Notes: Indicate source on test request form. Transport temp: Refrigerated Method: Biuret Unit code: 103240 CPT Code(s): 84157 Ref range: None established Reported: Within 24 hours Protein, Total, Serum Order code: 1075 Preferred specimen: 1.0 mL serum, SST or red top tube. Minimum specimen: 0.5 mL serum Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: Colorimetric Unit code: 101700 CPT Code(s): 84155 Ref range: 6.0-8.5 g/dL Reported: Within 24 hours Protein, Total, Urine Order code: 1520 Preferred specimen: 1.0 mL urine aliquot from a well-mixed 24-hour or random urine collection. Refrigerate 24-hour specimen during collection. No preservatives required. Record total volume and hours of collection on both the urine container and test request form. Minimum specimen: 0.5 mL urine aliquot Transport temp: Refrigerated Method: Pyrogallol Red Unit code: 102500 S1 0 CPT Code(s): 84156 Ref range: Up to150 mg/day Reported: Within 24 hours Protein/Creatinine Ratio, Urine Order code: 1521 Preferred specimen: 5.0 mL random urine with no preservatives. Minimum specimen: 1.0 mL urine Notes: Test includes: Creatinine, Total Protein, and Protein/Creatinine Ratio Transport temp: Refrigerated Method: Pyrogallol Red/Kinetic Unit code: 102501 CPT Code(s): 82570, 84156 Reported: Within 24 hours Prothrombin Gene Mutation (G20210A) Order code: 36482 Preferred specimen: 5.0 mL whole blood collected in lavender (EDTA), light blue (sodium citrate) or yellow (ACD Solution A or B) top tube. Minimum specimen: 3.0 mL whole blood Notes: Separate specimens should be submitted when multiple tests are ordered. Other acceptable: Liquid Based PAP Media Unacceptable: Heparin anticoagulant, severely hemolyzed specimens. Transport temp: Refrigerated Method: Polymerase Chain Reaction Unit code: 536482 CPT Code(s): 81240 Ref range: None Detected Reported: 1-5 days Test List 10-360 BBPL Directory of Services Prothrombin Time (PT) Order code: 2385 Preferred specimen: One full unopened light blue top tube (3.2% sodium citrate). Light blue top tube must be completely filled to ensure proper blood to anticoagulant ratio (9:1). Mix tube by gentle inversion 3-6 times immediately after collection. Do not uncap tube. If obtaining specimen with a butterfly, draw a waste tube first and discard. Minimum specimen: 90% filled light blue top tube (3.2% sodium citrate) or 0.5 mL plasma. Notes: Test includes INR. Other acceptable: If specimen will not arrive in the laboratory within 24 hours, centrifuge and transfer top half of plasma into a plastic transport tube and freeze immediately. Unacceptable: Gross hemolysis, clotted specimen, improper blood to citrate ratio, specimen collected in tube other than 3.2% citrate. Transport temp: Room temperature for light blue top tube. Send unopened tube to lab within 24 hours. Frozen for plasma. Method: Photo optical clot detection Unit code: 202330 CPT Code(s): 85610 Ref range: PT: 11.0 -14.0 seconds. INR: By report. Reported: Within 24 hours Prothrombin Time Mixing Study Order code: 84952 Preferred specimen: 2.0 mL frozen citrated (3.2% sodium citrate) plasma from a light blue top tube. Mix the light blue top tube by gentle inversion 10-12 times immediately after drawing. A completely filled blue top tube is required because the ratio of blood to citrate is critical (9:1). Centrifuge and transfer the top half of plasma to a plastic transport tube and freeze immediately. Minimum specimen: 1.5 mL plasma Unacceptable: Serum. Non-frozen or hemolyzed plasma. Transport temp: FROZEN Method: Mixing Study Unit code: 833250 CPT Code(s): 85610, 85611 Ref range: By report Reported: Within 24 hours Protime S1 0 See: Prothrombin Time Protriptyline Order code: 85000 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA), green (sodium heparin) or gray (sodium fluoride/potassium oxalate) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 833100 CPT Code(s): 80299 Ref range: Therapeutic Range: 70-240 ng/mL Toxic: > 400 ng/mL Reported: 1-5 days Prozac See: Fluoxetine Prudoxin See: Doxepin & Metabolite PSA See: Prostate Specific Antigen, PSA-Annual Screen Prostate Specific Antigen, Ultrasensitive Prostate Specific Antigen, Total and Free 10-361 Test List BBPL Directory of Services Pseudocholinesterase, Dibucaine Inhibition Order code: 81575 Preferred specimen: 1.0 mL serum, red top tube or SST. Minimum specimen: 0.25 mL serum or plasma Notes: Allow sample to clot completely at room temperature. Remove serum or plasma from cells ASAP. Sample must be drawn prior to surgery or more than two days following surgery. Do not draw in recovery room. Other acceptable: 1.0 mL lavender (EDTA) or green (sodium or lithium heparin) top tube. Unacceptable: Light blue (sodium citrate) or gray (oxalate/fluoride) top tubes. Whole blood, unseparated and hemolyzed samples. Transport temp: Refrigerated Method: Enzymatic Unit code: 807650 CPT Code(s): 82480, 82638 Ref range: Pseudocholinesterase, Total: 2,900-7,100 U/L Phenotype: By report Reported: 1-5 days Pseudocholinesterase, Serum See: Cholinesterase, Serum PT See: Prothrombin Time (PT) PTEN by FISH Order code: 35136 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block (0.2 cm³ piece of tissue) or 4 slides (4 micron thickness) from formalin-fixed paraffin block. Unacceptable: Paraffin-embedded tissue that has been decalcified. Transport temp: Room temperature Method: Fluorescence In-Situ Hybridization (FISH) Unit code: 535136 CPT Code(s): 88368 (x3) S1 0 Ref range: By report PTH Intact See: Parathyroid Hormone Intact with Calcium PTH Plus Minerals See: Parathyroid Hormone Plus Minerals PTH Related Peptide See: Parathyroid Hormone-Related Peptide PTH Related Protein See: Parathyroid Hormone Related-Peptide Pyridoxal Phosphate See: Vitamin B6, Plasma Test List 10-362 BBPL Directory of Services Pyruvate Kinase Order code: 85010 Preferred specimen: 1.0 mL whole blood, lavender (EDTA) top tube. Minimum specimen: 1.0 mL whole blood Notes: Do not freeze whole blood. Other acceptable: 1.0 mL whole blood, green (sodium heparin) or yellow (ACD Solution A or B) top tube. Unacceptable: Frozen specimens. Transport temp: Refrigerated Method: Enzymatic Unit code: 833650 CPT Code(s): 84220 Ref range: 9.0-22.0 U/g Hb Reported: 1-2 days Pyruvic Acid, Blood Order code: 83366 Preferred specimen: Special handling requirements: Draw whole blood by syringe or lavender (EDTA) or green (sodium or lithium heparin) top tube. Draw the specimen without the use of a tourniquet or within three minutes of applying the tourniquet, but before releasing the tourniquet. Immediately after blood is drawn, add exactly 1.0 mL of whole blood to a chilled pyruvic acid collection tube containing 2 mL 8% (w/v) perchloric acid. Collection tubes containing perchloric acid are available through BBPL Client Services or online using the BBPL Electronic Supply Form. Mix well for 30 seconds and place in an ice bath for 10 minutes. Centrifuge for 10 minutes at 1500 x g. Remove 2.0 mL of supernatant and transfer to a plastic transport tube and freeze. Follow specimen collection and handling instructions included with the collection tube. If less than 1 mL of blood is added to collection tube, pH of the supernatant will be too low for testing to be performed. Patient should be fasting and at complete rest. Patient should avoid any exercise of the arm or hand before or during collection. Minimum specimen: 1.0 mL supernatant Unacceptable: Specimens not prepared as indicated. Transport temp: Frozen Method: Quantitative Enzymatic Unit code: 833660 CPT Code(s): 84210 Ref range: 0.030-0.107 mmol/L (venous blood) Reported: 1-2 days S1 0 Q-Fever See: Coxiella burnetii (Q-Fever) Antibodies, IgG & IgM with Reflex to Titer Coxiella burnetii (Q-Fever) Antibody IgG, Phase I & II by IFA QuantiFERON-TB Gold Order code: 5403 Preferred specimen: The QuantiFERON® collection kit contains instructions for the draw of three special QuantiFERON® collection tubes (one each): (1) gray-top (with white ring), nil control; (2) red-top (with white ring), TB antigen; (3) purple-top (with white ring), mitogen control. All three tubes are required for a single test result. Each tube is designed to draw only 1 mL and fill time may be longer than other blood collection tubes. Under or overfilling of the tubes may lead to erroneous results. Follow directions in the QuantiFERON® draw kit for optimal results. Maintain specimens at room temperature. Do not centrifuge, refrigerate, or ship tubes on ice. Contact BBPL Client Services for special collection kit and questions about collection, shipment, and stability of samples. TIME SENSITIVE TEST: Specimens should be collected and shipped to the laboratory within 16 hours of collection and not on holidays. Minimum specimen: 1 mL for each collection tube Other acceptable: Alternate handling procedure: After collection and mixing, QuantiFERON® tubes may be transferred to a 37ºC incubator, incubated upright for 16-24 hours, and shipped to the laboratory within 48 hours following incubation. Ship at room temperature. Do not centrifuge or refrigerate tubes. Indicate on the test request form the tube incubation temperature and hours of incubation. Follow the incubation instructions provided in the QuantiFERON® collection kit. Unacceptable: Specimens centrifuged, refrigerated or frozen. Specimens more than 16 hours old on receipt in laboratory. Transport temp: Room temperature Method: Enzyme-Linked Immunosorbent Assay Unit code: 354001 CPT Code(s): 86480 Ref range: By report Reported: 2-3 days 10-363 Test List BBPL Directory of Services Quetiapine (Seroquel) Order code: 83714 Preferred specimen: 1.0 mL serum, red top tube. Remove serum from cells within 2 hours of collection. Do not collect in SST. Minimum specimen: 0.5 mL serum or plasma Other acceptable: 1.0 mL plasma, lavender (EDTA) or green (sodium or lithium heparin) top tube. Remove plasma from cells within 2 hours of collection. Unacceptable: Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution) tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography-Tandem Mass Spectrometry Unit code: 833710 CPT Code(s): 80299 Ref range: The following therapeutic ranges and critical values have been suggested, but not validated. Trough Draws (Preferred) Therapeutic range: 70-170 ng/mL Critical value: Greater than 1000 ng/m Peak Draws (At 1.5 hour post dose, NOT recommended) Therapeutic range: 100-1000 ng/mL Critical value: Greater than 1500 ng/mL Reported: 1-5 days Quinidine Order code: 1195 Preferred specimen: 1.0 mL serum, red top tube. Do not draw in SST. Minimum specimen: 0.3 mL serum or plasma Notes: Collection: Peak: quinidine sulfate: 1½ hours after dose, quinidine gluconate: four hours after dose; Trough: immediately prior to next dose. Remove serum or plasma from cells ASAP. Other acceptable: 1.0 mL plasma, green (sodium or lithium heparin) top tube. Unacceptable: Separator tubes or gels, severe hemolysis, lipemia, or icteric specimens. Transport temp: Refrigerated Method: Immunoassay Unit code: 833715 CPT Code(s): 80194 Ref range: Therapeutic: 2.0-5.0 µg/mL S1 0 Reported: 1-3 days RA Factor See: Rheumatoid Factor RA Panel See: Arthritic Series Arthritic Series I Arthritic Series II Arthritis Panel Rabies Antibody, IgG (Vaccine Response) Order code: 85045 Preferred specimen: 0.5 mL serum, gel-barrier tube. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.1 mL serum or plasma Notes: This test is only intended for vaccine response, not for diagnosis of infection. Other acceptable: 0.5 mL plasma, lavender (EDTA), green (sodium heparin), yellow (ACD solution A), or light blue (sodium citrate) top tube. Unacceptable: CSF. Hemolyzed, icteric, or lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 833800 CPT Code(s): 86790 Ref range: 0.50 EU/mL or greater: Represents adequate protection against rabies virus following vaccination. Reported: 1-8 days Raji Cell See: Immune Complex, Raji Cell Rapamune See: Sirolimus Test List 10-364 BBPL Directory of Services Rapid Flu, A & B See: Influenza Antigen Screen A & B Rapid Group A Strep Antigen See: Streptococcus Group A Rapid Antigen with Reflex to Culture Rapid Urease for Helicobacter pylori See: Helicobacter pylori CLO Test, Gastric Rapiflux See: Fluoxetine RBC Antibody Screen See: Antibody Screen RBC Folate See: Folate, RBC Reducing Substances, Fecal Order code: 2155 Preferred specimen: 5 gm aliquot of stool in a clean unpreserved stool transport container. Minimum specimen: 1 gm aliquot of stool Unacceptable: Specimens in preservative or diapers. Transport temp: Frozen Method: Semi-quantitative Colorimetry Unit code: 835641 S1 0 CPT Code(s): 84376 Ref range: Negative Reported: Within 24 hours Rela See: Carisoprodol & Meprobamate 10-365 Test List BBPL Directory of Services Renal Panel Order code: 5360 Preferred specimen: 2.0 mL serum, red top tube or SST. Minimum specimen: 1.0 mL serum Notes: Test includes: Albumin BUN BUN/Creatinine Ratio Calcium Carbon Dioxide Chloride Creatinine Glucose Inorganic Phosphate Potassium Sodium Glomerular Filtration Rate Other acceptable: 4 red top microtainer tubes Transport temp: Refrigerated Method: See individual tests Unit code: 90115 CPT Code(s): 80069 Ref range: Albumin BUN Calcium Carbon Dioxide Chloride Creatinine Glucose Inorganic Phosphate Potassium Sodium 3.5-5.5 g/dL 10-26 mg/dL 8.5-10.5 mg/dL 20-32 mmol/L 98-110 mmol/L 0.4-1.5 mg/dL 70-99 mg/dL 2.5-4.8 mg/dL 3.5-5.0 mmol/L 136-145 mmol/L Reported: Within 24 hours Renin Activity Order code: 85190 Preferred specimen: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells, transfer to a plastic transport tube and FREEZE immediately. CRITICAL FROZEN. Separate samples must be submitted when multiple tests are ordered. Minimum specimen: 0.8 mL plasma Notes: It is recommended that the patient be ambulatory for at least 30 minutes before blood collection. In order to facilitate interpretation of test results, the patient should be taken off medications for at least three weeks prior to sample collection. Dietary sodium levels during the period prior to testing can affect renin levels. Unacceptable: Serum; heparinized, citrated, or oxalated plasma; or refrigerated or hemolyzed specimens. Recently administered isotopes. Transport temp: CRITICAL FROZEN Method: Radioimmunoassay Unit code: 835700 CPT Code(s): 84244 Ref range: By report Reported: 1-3 days Respiratory Antibody Profile I Order code: 94658 Preferred specimen: 4.0 mL serum, red top tube or SST. Remove serum from cells ASAP and transfer to a plastic transport tube. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent". Minimum specimen: 1.0 mL serum Notes: Test includes: Adenovirus Antibodies, IgG & IgM Chlamydia Antibodies, IgG & IgM Legionella pneumophila Antibody Mycoplasma pneumoniae Antibodies, IgG & IgM Unacceptable: Severely lipemic, hemolyzed, icteric, turbid, heat-inactivated, or contaminated specimens. Transport temp: Refrigerated Method: Enzyme-Linked Immunosorbent Assay/Indirect Fluorescent Antibody Unit code: 94658 CPT Code(s): 86603 (x2), 86631 (x3), 86632 (x3), 86713, 86738 (x2) Ref range: See individual tests. Reported: 1-6 days Test List 10-366 S1 0 BBPL Directory of Services Respiratory Pathogens Profile, Qualitative Real-Time PCR Order code: 39000 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Notes: Profile includes: Influenza A, Influenza A Subtypes H1, H1-2009, & H3, Influenza B, Parainfluenza Types 1, 2, 3, Respiratory Syncytial Virus, Human Metapneumovirus, Rhinovirus, Adenovirus, Bordetella pertussis, Chlamydophila pneumoniae, Mycoplasma pneumoniae, Coronavirus 229E, Coronavirus OC43, Coronavirus HKU1, and Coronavirus NL63. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction Unit code: 539000 CPT Code(s): 87486, 87581, 87633, 87798 Ref range: Negative Reported: 1-2 days Respiratory Syncytial Virus (RSV) Antibody, CF Order code: 83576 Preferred specimen: 2.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Notes: Children younger than six months of age may not make antibodies in response to infection. Unacceptable: Hemolyzed, lipemic, or grossly contaminated specimens. Transport temp: Refrigerated Method: Complement Fixation (CF) Unit code: 835756 CPT Code(s): 86756 Ref range: Less than 1:8 Reported: 3-5 days Respiratory Syncytial Virus (RSV) Antigen Order code: 3470 Preferred specimen: Nasopharyngeal swab; Nasal swab; Nasopharyngeal aspirates (0.5-1.0 mL) or washes (2-4 mL) placed immediately into M6 (red cap) viral transport tube. Submit specimen to laboratory within 48 hours. Notes: Viral transport tube must be tightly sealed to prevent leakage. The wire from the nasopharyngeal swab cannot stick out under the screw cap of the viral transport tube. S1 0 Other acceptable: Specimens in M4, M4RT, or M5 viral transport media or normal saline (only enough saline to cover swab). Unacceptable: Dry swabs or swabs with wooden shaft. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 402500 CPT Code(s): 87420 Ref range: Negative Reported: Within 24 hours Respiratory Syncytial Virus (RSV) RNA, Qualitative Real-Time PCR Order code: 39035 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated Method: Real-Time Polymerase Chain Reaction Unit code: 539035 CPT Code(s): 87801 Ref range: Negative Reported: 1-2 days Restasis See: Cyclosporine A Restoril See: Temazepam and Metabolite, Quantitative 10-367 Test List BBPL Directory of Services Reticulin Antibody, IgA with Reflex to Titer Order code: 83499 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.15 mL serum Notes: All positives are titered to endpoint. If Reticulin Antibody is 1:5, then a titer will be added at an additional charge. Unacceptable: Plasma. Severely lipemic, hemolyzed, or contaminated specimens. Transport temp: Refrigerated Method: Semi-Quantitative Indirect Fluorescent Antibody Unit code: 835801 CPT Code(s): 86255 Ref range: Reticulin Antibody, IgA Screen: < 1:5 No antibody detected Reticulin Antibody, IgA Titer: < 1:5 No antibody detected IgA class reticulin antibodies are found in dermatitis herpetiformis (25%) and celiac disease (60%), but not in other autoimmune problems. IgG class reticulin antibodies are found in other disease states, especially bullous dermatoses, and sometimes in normal patients.IgA class reticulin antibodies are found in dermatitis herpetiformis (25%) and celiac disease (60%), but not in other autoimmune problems. IgG class reticulin antibodies are found in other disease states, especially bullous dermatoses, and sometimes in normal patients. Reported: 1-5 days Reticulocyte Count Order code: 2415 Preferred specimen: One 3-4 mL lavender top tube (EDTA). Refrigerate EDTA tube if specimen will not be received in laboratory within 24 hours of collection. Stability: Room temperature 24 hours, refrigerated 48 hours. Minimum specimen: 1.0 mL EDTA whole blood (lavender tube) or 250 uL (microtainer tube) Unacceptable: Frozen, clotted, or grossly hemolyzed specimens. Tubes not filled with minimum volume. Transport temp: Refrigerated Method: Automated Hematology Analyzer Unit code: 201395 CPT Code(s): 85045 Ref range: Reticulocyte Absolute: 30.0-100.0 thou/cumm Reticulocyte %: 0.70-2.50% Reported: Within 24 hours S1 0 Retigabine See: Ezogabine and Metabolite Retinol Binding Protein Order code: 85205 Preferred specimen: 1.0 ml serum, red top tube or SST. Remove serum from cells ASAP. Minimum specimen: 0.5 mL serum Unacceptable: Plasma, severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Nephelometry Unit code: 835900 CPT Code(s): 83883 Ref range: 3-6 mg/dL Reported: 1-4 days RF See: Rheumatoid Factor Rheumatoid Arthritis Panel See: Arthritic Series Arthritic Series I Arthritic Series II Arthritis Panel Test List 10-368 BBPL Directory of Services Rheumatoid Factor Order code: 5080 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Unacceptable: Extremely lipemic specimens Transport temp: Refrigerated Method: Nephelometry Unit code: 350400 CPT Code(s): 86431 Ref range: <20 IU/mL Reported: 1-2 days Rheumatoid Factor, Body Fluid Order code: 83379 Preferred specimen: 1.0 mL body fluid. Centrifuge to remove cellular material. Remove body fluid from cellular material and transfer to a plastic transport tube. Indicate source on test request form. Minimum specimen: 0.5 mL body fluid Unacceptable: Breast milk and salivary fluid. Specimens too viscous to be aspirated by instrument. Transport temp: Refrigerated Method: Quantitative Immunoturbidimetry Unit code: 833795 CPT Code(s): 86431 Ref range: None Established Reported: Within 24 hours Rhinovirus RNA, Qualitative Real-Time PCR Order code: 39050 Preferred specimen: Nasopharyngeal swab in viral transport media. Minimum specimen: 1 swab in transport media or 1 mL fluid/wash. Other acceptable: Nasopharyngeal swab in sterile saline; nasal wash or bronchial lavage/wash in sterile container. Unacceptable: Dry swabs, wooden swabs, or calcium alginate swabs. Specimens greater than 72 hours. Transport temp: Refrigerated S1 0 Method: Real-Time Polymerase Chain Reaction Unit code: 539050 CPT Code(s): 87798 Ref range: Negative Reported: 1-2 days Riboflavin (Vitamin B2) See: Vitamin B2 Ribosomal P Protein Antibody Order code: 83593 Preferred specimen: 1.0 mL serum, SST. Remove serum from cells ASAP. Minimum specimen: 0.2 mL serum Unacceptable: Plasma and other body fluids. Severely lipemic or bacterially contaminated specimens. Transport temp: Refrigerated Method: Multi-Analyte Fluorescent Detection Unit code: 835930 CPT Code(s): 83516 Ref range: 29 AU/mL or less: Negative 30-40 AU/mL: Equivocal 41 AU/mL or greater: Positive Reported: 1-2 days 10-369 Test List BBPL Directory of Services Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibodies, IgG & IgM Order code: 85210 Preferred specimen: 0.9 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.4 mL serum Notes: Titer by Indirect Fluorescent Antibody will be added if IgG positive. Unacceptable: Severely lipemic, contaminated, or hemolyzed samples. Transport temp: Refrigerated Method: Enzyme Immunoassay/Indirect Immunofluorescence Assay Unit code: 836053 CPT Code(s): 86757 (x2) Ref range: Rocky Mountain Spotted Fever Antibody, IgG: Negative: <1:64 Positive: 1:64 Recent/active: >1:64 Rocky Mountain Spotted Fever Antibody, IgM: Negative: <9 Units Equivocal: 9-11 Units Positive >11 Units Reported: 1-5 days Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgG Order code: 83651 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Notes: Titer by Indirect Fluorescent Antibody will be added if IgG positive. Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay/Indirect Immunofluorescence Assay Unit code: 836051 CPT Code(s): 86757 Ref range: Negative: <1:64 Positive: 1:64 Recent/active: >1:64 Reported: 1-5 days S1 0 Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgM Order code: 83605 Preferred specimen: 0.4 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Unacceptable: Severely lipemic, contaminated, or hemolyzed specimens. Transport temp: Refrigerated Method: Enzyme Immunoassay Unit code: 836052 CPT Code(s): 86757 Ref range: Negative: <9 Units Equivocal: 9-11 Units Positive: >11 Units Reported: 1-5 days Risolid See: Librium & Nordiazepam Test List 10-370 BBPL Directory of Services Risperidone & Metabolite Order code: 83612 Preferred specimen: 1.0 mL serum, red top tube. Do not collect in SST. Remove serum from cells within 2 hours of collection and transfer serum to a plastic transport tube. Minimum specimen: 0.5 mL serum or plasma Notes: Pre-dose (trough) draw - At steady state concentration. Other acceptable: 1.0 mL plasma, lavender (EDTA) top tube. Remove plasma from cells within 2 hours of collection and transfer to a plastic transport tube. Unacceptable: Separator tubes or gels, light blue (citrate) or yellow (SPS or ACD solution) top tubes. Transport temp: Refrigerated Method: Quantitative Liquid Chromatography/Tandem Mass Spectrometry Unit code: 836125 CPT Code(s): 80299 Ref range: Therapeutic range: Not well established Total (Resiperidone and Metabolite): 20-60 ng/mL Toxic range: Not well established Reported: 1-5 days Ristocetin Cofactor See: von Willebrand Factor Activity (Ristocetin Cofactor) Ritalin See: Methylphenidate & Metabolite RNA Polymerase III Antibody, IgG Order code: 86240 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Transport temp: Refrigerated Method: Semi-Quantitative Enzyme-Linked Immunosorbent Assay Unit code: 836240 S1 0 CPT Code(s): 83516 Ref range: 19 Units or less: Negative 20-39 units: Weak Positive 40-80 Units: Moderate Positive 81 Units or greater: Strong Positive Reported: 1-4 days RNP (U1) (Ribonucleic Protein) (ENA) Antibody, IgG Order code: 86251 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells within 2 hours of collection and transfer to a plastic transport tube. Minimum specimen: 0.2 mL serum Unacceptable: Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens. Transport temp: Refrigerated Method: Semi-Quantitative Multiplex Bead Assay Unit code: 836251 CPT Code(s): 86235 Ref range: Reference Interval: 29 AU/mL or less: Negative 30-40 AU/mL: Equivocal 41 AU/mL or greater: Positive Reported: 1-2 days Rocky Mountain Spotted Fever See: Rickettsai rickettsii (Rocky Mountain Spotted Fever) Antibody, IgG Rickettsai rickettsii (Rocky Mountain Spotted Fever) Antibody, IgM Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibodies, IgG & IgM 10-371 Test List BBPL Directory of Services ROS1 by FISH Order code: 32340 Preferred specimen: Formalin-fixed, paraffin-embedded tissue block (0.2 cm³ piece of tissue) or 4 slides (4 micron thickness) from formalin-fixed paraffin block. Unacceptable: Paraffin-embedded tissue that has been decalcified. Transport temp: Room temperature Method: Fluorescence in situ Hybridization (FISH) Unit code: 532340 Ref range: By report Reported: 2-10 days Rotavirus Antigen, Stool Order code: 3460 Preferred specimen: 1 g solid stool (pea size portion) or 0.5 mL liquid stool in clean, unpreserved screw-cap container, frozen. Other acceptable: Fresh stool specimen in a clean, unpreserved screw-cap container is acceptable only if the specimen will be received in the testing laboratory within 2 hours of collection. Transport at room temperature. Unacceptable: Stool specimens containing preservatives or media, unfrozen specimens greater than 2 hours old. Transport temp: Frozen Method: Membrane Enzyme-linked Immunosorbant Assay Unit code: 402400 CPT Code(s): 87425 Ref range: Negative Reported: Within 24 hours RPP See: Respiratory Pathogens Profile, Qualitative Real-Time PCR RPR (Rapid Plasma Reagin) Order code: 5250 Preferred specimen: 0.5 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.3 mL serum S1 0 Notes: A reactive result will automatically flex to Treponema pallidum Antibody by Particle Agglutination. Unacceptable: Severely hemolyzed or lipemic specimens. Grossly contaminated specimens. CSF or other body fluids. Transport temp: Refrigerated Method: Charcoal Flocculation Unit code: 350500 CPT Code(s): 86592 Ref range: Non-Reactive Reported: 1-3 days RSV See: Respiratory Syncytial Virus, (RSV) Antigen Respiratory Syncytial Virus RNA, Qualitative Real-Time PCR Respiratory Syncytial Virus (RSV) Antibody, CF Rubella Antibody, IgG Order code: 5280 Preferred specimen: 1.0 mL serum, red top tube or SST. Remove serum from cells and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Unacceptable: Heat-inactivated specimens. Transport temp: Refrigerated Method: Chemiluminescent Immunoassay Unit code: 352500 CPT Code(s): 86762 Ref range: Non-Immune: < 5.0 IU/mL Equivocal: 5.0-9.9 IU/mL Immune: >10.0 IU/mL Reported: Within 24 hours Test List 10-372 BBPL Directory of Services Rubella Antibody, IgM Order code: 85310 Preferred specimen: 1.0 mL serum, red top tube or SST. Allow specimen to clot completely at room temperature. Remove serum from cells ASAP and transfer to a plastic transport tube. Minimum specimen: 0.5 mL serum Notes: Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples. Please mark specimens plainly as "acute" or "
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