1. No category

S.No. Principal Investigator
1
DrDilip Mathai Department
Project Title
Infectious Diseases
A double blind, randomized, parallel, placebo control design study to
Training and Research
determine the effect of addition of Vitamin D to conventional anti TB
Centre
therapy CTRI Nos.
CTRI/2007/091/000008 The role of N-acetyl cysteine in patients with newly detected sputum
positive pulmonary tuberculosis, a double blind randomised control
2
Dr. Dhanasekar. K.R Pharmacology
trial CTRI/2007/091/000012 Modafinil for clozapine related adverse effects in people with
schizophrenia or schizoaffective disorders in remission: a
3
Dr. Prathap Tharyan Psychiatry
randomized, placebo controlled trial CTRI/2007/091/000020 A randodomized double blinded case controlled study of the effects
Physical Medicine and
4
Dr. Shiela Mary Varghese Rehabilitation
of Zoledronic acid on bone mineral density in Osteoporotic chronic
spinal cord injury patients CTRI/2007/091/000027 A Phase 2, Randomized, Double masked, placebo- controlled study
to evaluate the efficacy of SNX-1012 in Reducing the Duration and
Severity of Ulcerative Oral Mucositis in patients receiving Cytotoxic
5
Dr. Subhashini John
Radiotherapry
Chemotherapy for Breast or Lung Cancer.
6
Dr. Raju Titus Chacko
Medical Oncology
for subjects enrolled in other Tivozanib Protocol
Obstetrics &
A randomized controlled trial to study the effect of intravenous
Gynaecology,
hydration on the course of labor
CTRI/2007/091/000044
A Rollover Protocol to allow continued access to Tivozanib (AV951)
7
Dr.Kavitha Abraham CTRI-2007/091/000043
CTRI/2008/091/000003 Dr. Smitha Elizabeth
8
George Instillation of lignocaine down the endotracheal tube to attenuate
Anaesthesia
extubation response CTRI/2008/091/000027 Radiation Oncology Unit Phase II study of Concurrent Chemoirradiation with weekly
9
Dr. Thomas Samuel Ram - I
Paclitaxel and Cisplatin in the treatment of Carcinoma of the Cervix CTRI/2008/091/000029 Single blinded randomly allocated comparative study to compare the
Mary Verghese Institute efficacy of body weight supported treadmill training with body weight
of Rehabilitation,PMR
supported over ground training in patients with ASIA grade C
10
Senthil Velkumar.T Department,
tetraplegia. CTRI/2008/091/000034 11
Dr. Annie Regi OG Unit III,
Treatment approaches for pre eclampsia in low resource settinga CTRI/2008/091/000118 A prospective, single arm, open trial to assess the safety and
efficacy of Fondaparinux in patients with unstable angina and nonST elevation myocardial infarction compared to historical controls
12
Dr. Leena Thomas cardiology
Dr. Smitha Elizabeth
13
George treated with Enoxaparin. CTRI/2008/091/000309 Instillation of lignocaine down the endotracheal tube to attenuate
Anaesthesia
extubation response CTRI/2008/091/000027 To evaluate the efficacy of low dose Ketamine in providing analgesia
14
Dr. Sam Joel Anaesthesia
during labour
CTRI/2008/091/000264 A Pivotal trial to determine the efficiency & safety of AP23573 when
administered as Maintenance therapy to Patients with Metastatic
15
Dr. Subhashini John
Radiotherapry
Soft Tissue or Bone Sarcoma.
CTRI/2008/091/000008
Community-based cluster randomized trial of Ready-to-use
16
Azara Sneha Singh MBBS Student
therapeutic food in malnourished children <5 years of age CTRI/2009/091/000007 A randomised trial comparing short-term outcomes of "Uncut" Rouxen-Y gastrojejunostomy and standard Roux-en-Y gastrojejunostomy
following partial gastrectomy/palliative bypass for gastric
17
Dr. Nagaraj Palankar
Surgery Unit III
adenocarcinoma CTRI/2009/091/000071 A randomised controlled clinical trial to investigate the role of
autologous bone marrow derived cells in the healing of chronic
18
Dr. Prakash Jain General Surgery Unit 5, wounds Efficacy of Group Counseling in the Comprehension of Informed
CTRI/2009/091/000250 Consent as Compared to Individual Counseling: A Randomized
19
Dr. Rajiv Sarkar GI Sciences
20
Dr. Sudip Bandyopadhyay Surgery Unit 5 Controlled Trial The effect of preoperative carbohydrate loading in major colorectal
CTRI/2009/091/000612 resections: a randomized controlled trial A multicentre, randomized, open label, two-period, two-treatment,
CTRI/2009/091/000070 two-way crossover, bioequivalence study comparing Capecitabine
tablets 500mg (Manufactured by Intas Pharmaceuticals Ltd., India)
to the reference listed drug XELODA 500mg tablets (Manufactured
by Roche Pharma AG, Germany) in patients of Locally Advanced or
Metastatic Breast Cancer or Metastatic Colorectal Cancer under fed
21
Dr. Subhashini John
Radiotherapry
condition.
CTRI/2009/091/000637
An Open Label, Multicenter Phase I/II Study Of Selective Cyclin
Dependent Kinase Inhibitor P276-00 In Combination With Radiation
In Subjects With Recurrent And/Or Locally Advanced Squamous
22
Dr. Subhashini John
Radiotherapry
Cell Carcinoma Of Head And Neck.
CTRI/2009/091/000115
Probiotics for infectious diarrhea in children in south India CTRI/2010/091/000339 Gastrointestinal
23
Dr. Gagandeep Kang Sciences
A phase II randomized trial on benefit of amylase resistant starch in
reducing acute proctitis in patients undergoing pelvic radiation for
24
Dr. Balu Krishna S Radiotherapy unit 1, carcinoma cervix - PILOT PHASE CTRI/2010/091/000427
An open labelled randomized controlled trial comparing costs and
clinical outcomes of open endotracheal suctioning with closed
endotracheal suctioning in mechanically ventilated medical intensive
25
Dr. Deepu David Medicine II,
care patients CTRI/2010/091/001076 MIDLINE VS TRANSVERSE INCISION FOR RIGHT, LEFT AND
26
Dr. Titus D.K Surgery Unit-V SEGMENTAL COLECTOMY CTRI/2010/091/001207
27
Dr. Shubhanker Mitra
Medicine Unit II vabradine in controlling tachycardia among critically ill patients CTRI/2010/091/002969
Production and delivery of antibody fragments against
28
Dr. Gagandeep Kang GI Sciences
gastrointestinal pathogens by lactobacilli CTRI/2010/091/003002 Is the use of bone marrow derived mononuclear cells safe and
feasible in prevention of wound breakdown in patients undergoing
abdominoperineal excision after neoadjuvant Chemoradiotherapy for
29
Dr Johann Boaz General Surgery,Unit -5 Carcinoma Rectum ? a Pilot study CTRI/2010/091/000094 Is the use of bone marrow derived mononuclear cells safe and
feasible in prevention of wound breakdown in patients undergoing
abdominoperineal excision after neoadjuvant Chemoradiotherapy for
30
Dr. Raviraj. R Anaesthesiology
31
Dr Gagandeep Kang GI Sciences
Carcinoma Rectum ? a Pilot study CTRI/2010/091/002943 Hospital-based randomized control trial of racecadotril in acute
diarrhoeal disease in children 6 months to 5 years of age
CTRI/2010/091/003067
A Randomized, Active Therapy Controlled Phase 2 Study to Assess
the Safety and Efficacy of ADXS11-001 with or without Cisplatin as
32
Dr. Subhashini John
Radiotherapry
2nd Line Therapy for the Treatment of Recurrent Cervix Cancer.
CTRI/2010/091/001232
A phase-II, Randomised, Double-blind, Placebo-controlled, Multicentre study to assess the efficacy and safety of AZD8931 in
combination with Anastrozole, compared to Anastrozole alone, in
post menopausal women with Hormone receptor positive, endocrine
33
Dr. Subhashini John
Radiotherapry
therapy-naïve, Locally-advanced or metastatic breast cancer (MINT) CTRI/2010/091/002961
Phase III double-blind, placebo-controlled study of post-operative
adjuvant concurrent chemoradiotherapy (CTRT) with or without
nimotuzumab for stage III/IV head and neck squamous cell cancer
34
Dr. Subhashini John
Radiotherapry
(HNSCC).
CTRI/2010/091/001233
FORTIS-M: A Phase 3, randomized, double blinded, placebocontrolled study of oral talactoferin in addition to best supportive
cere in patients with non-small cell lung cancer who have failed two
35
Dr. Subhashini John
Radiotherapry
or more proir treatment regimens.
CTRI/2010/091/000034
A Phase III, Randomized, Controlled, Multi Center, Open-Label
Study to Compare Tivozanib (AV-951) to Sorafenib in Subjects with
36
Dr. Raju Titus Chacko
Medical Oncology
37
Dr. Thambu David SudarsanMedicine
Advanced Renal Cell Carcinoma.
CTRI/2010/091/000026
Randomized trial of diet supplementation in HIV and tuberculosis CTRI/2010/091/006112 [
An Extension Treatment Protocol for Subjects who have participated
38
39
Dr. Raju Titus Chacko
Dr. Raju Titus Chacko
Medical Oncology
Medical Oncology
in a Phase 3 Study of Tivozanib vs. Sorafenib in Renal Cell
TEMP UTRN 060332551-
Carcinoma (Protocol AV-951-09-301)”
0801201016251569
A Phase 2, Placebo-Controlled, Randomized, Discontinuation Trial
TEMP UTRN 105647370-
of AV-951 in Patients with Renal Cell Carcinoma
211220057179
Protective eyewear and educational interventions to prevent occular
injuries among stone quarry workers: A pragmatic cluster
40
Dr. Renu Raju Opthalomology
randomized controlled trial CTRI/2011/05/001707 Role of subglottic suctioning in the prevention of ventilator
associated pneumonia in critically ill patients requiring invasive
41
DrVarsha Kiron General Medicine mechanical ventilation in a tertiary care hospital in South India. CTRI/2011/06/001840 Use of Nintendo Wii™ gaming console for rehabilitation of children
42
Dr. Jane Elizabeth Sajan Department of PMR, with cerebral palsy CTRI/2011/11/002137 Use of Amniotic Membrane as biological dressing for the
Dr Bobeena Rachel
43
Chandy management of pressure ulcers in comparison with conventional
PMR
saline dressings. CTRI/2011/11/002167 The development and evaluation of m-Health service in the control
44
Dr. Dilip Mathai IDTRC IV
of Tuberculosis (TB) in India. CTRI/2011/07/001889 Gestational diabetes well controlled on medical nutritional therapy: a
45
Dr Phijam Dhaneshwor Obstetrics and
randomized trial of active induction of labour compared with
gynaecology Unit III expectant management
CTRI/2011/12/002290 Use of Amniotic Membrane as biological dressing for the
Dr Bobeena Rachel
46
Chandy management of pressure ulcers in comparison with conventional
PMR, saline dressings. CTRI/2011/11/002167 An open label, phase II trial of afatinib with or without vinorelbine for
47
Dr. Raju Titus Chacko
Medical Oncology
the treatment of HER2-overexpressing Inflammatory Breast Cancer REF/2011/11/002993
Effect of deep slow breathing exercises on spontaneous respiratory
48
Dr. Elizabeth Tharion
Physiology
rate and short-term heart rate variability. CTRI/2011/091/000078 A prospective phase II study to assess the feasibility, efficacy and
tolerance of neoadjuvant Chemotherapy with ultra fractionated
radiotherapy prior to definitive chemoradiation in stage IIB, IIIA and
49
Dr. Saikat Das Radiation Oncology
IIIB Squamous cell carcinoma of cervix CTRI/2012/01/002358 Well Baby Clinic
50
Dr. Rajeev Zachariah
Department of Child
Comparison of immunogenicity of a 3 dose and a 5 dose schedule
Health of oral rotavirus vaccine in south Indian infants CTRI/2012/02/002454 GBM Study [Protocol Number- SPI-LUC-11-01]An International,
Multi-Center, Randomized, Double Blind Placebo Controlled Phase
II Study to Evaluate the Safety and Efficacy of Lucanthone
Administered as an Adjunct to Radiation and Temozolomide for
51
Dr. Subhashini John
Radiotherapry
Primary Therapy of Glioblastoma Multiforme
CTRI/2012/04/002616
Prevalence of phlebitis and comparison of the effectiveness of
heparinoid application and ichthammol glycerin application on
52
Ms. Minnu Thomas 53
Dr Vrisha Madhuri 54
Dr. Gagandeep Kang 55
Dr. BS Ramakrishna MSc.Nursing student phlebitis among patients on peripheral intravenous therapy Paediatric
Autologous cultured chondrocytes from iliac crest in the treatment of
Orthopaedics, physeal bars in children Gastrointestinal
Effect of probiotic and zinc supplementation on systemic immune
Sciences response to oral rotavirus and oral poliovirus vaccination Gastrointestinal
Esterified starch and oral rehydration solution as a treatment for
Sciences acute infectious diarrhoea CTRI/2012/05/002629 CTRI/2012/05/002638 CTRI/2012/05/002677 CTRI/2012/05/002680 Prospective, randomized, placebo-controlled, double-blind,
multicenter, parallel group study to assess the efficacy,safety and
56
Dr. Debashish Danda
Clinical Immunology
tolerability of macintentan in patients with ischemic digital ulcers
and Rheumatology
associated with Systemic Sclerosis
CTRI/2012/05/002684
Effectiveness of expressed human breast milk, 24% oral sucrose vs
placebo(sterile water)for pain relief in preterm infants undergoing a
heel prick procedure in the nursery of Christian Medical College and
57
Ms Sophia Philip MSc Nursing student Hospital, Vellore.
CTRI/2012/06/002730 A surveillance of invasive disease caused by S.pneumoniae or
H.influenzae or N.meningitidis in children less than 5 years of age in
58
Dr Shyam Kukreja Pediatrics India CTRI/2012/06/002726 Double Blind Randomised placebo controlled trial to evaluate
intravenous clonidine as a hypotensive agent in Functional
59
Dr Subramani K Surgical Intensive Care Endoscopic Sinus surgery CTRI/2012/07/002790 Frequency of migraine associated vertigo in patients visiting the
60
Dr Anjali Lepcha Audiovestibular Unit
audiovestibularclinic in a tertiary care hospital and response to
Department of ENT specific treatment for migraine CTRI/2012/07/002779 A Multicenter, Phase II/III Study to Assess Radiation Induced
Mucositis in Patients with Locally Advanced Squamous Cell
Carcinoma of the Head And Neck Administered Cisplatin And
61
Dr. Subhashini John
Radiotherapy unit 1, Radiation with or without P276-00.
CTRI/2012/07/002783 A prospective observational trial to characterize the association of
abnormal central venous saturation to the morbidity and mortality of
patients admitted to the intensive care unit with a diagnosis of sepsis
62
Dr K Subramani Anaesthesia or trauma. CTRI/2012/08/002889 Serum Myoglobin compared to Serum Creatine Phosphokinase as a
Dr Chakravarthy Joel
63
Jacob predictor of renal failure in patients with post traumatic
Anaesthesia rhabdomyolysis CTRI/2012/08/002892 PROSPECTIVE RANDOMIZED CONTROLLED TRIAL
COMPARING EARLY POST OPERATIVE COMPLICATIONS IN
PATIENTS UNDERGOING LOOP COLOSTOMY WITH AND
64
Dr. Joshua Franklyn General surgery unit 2 WITHOUT A ROD CTRI/2012/09/002949 Effect of Inactivated Poliovirus Vaccine on Gut Immunity against
65
Dr. Jacob John
Community Health
Poliovirus in children who have received Oral Polio Vaccine CTRI/2012/09/003005 Vitamin D deficiency in postmenopausal women with pelvic floor
66
Dr R N Preethi Obstetrics and Gynecolo disorders CTRI/2012/11/003085 Randomized double-blind placebo controlled clinical trial to
determine the efficacy of mannitol in reducing intra-compartmental
67
Dr Thilak Orthopedics Unit III
pressure CTRI/2012/11/003089 Comparison of extended and short infusion regimen of meropenem
68
Dr Binu Susan Mathew Clinical Pharmacology
in critically ill patients, an observational study. CTRI/2012/11/003095 Randomised trial of pulsed Actinomycin D versus MTX infusion in
69
Dr. Anitha Thomas Obstetrics and Gynecolo low risk gestational trophoblastic neoplasia CTRI/2012/11/003120 A Randomized double blind controlled trial comparing two regimens
70
Dr Mintoo M Tergestina Paediatrics
of Vitamin D supplementation in preterm neonates CTRI/2012/11/003154 Does normal saline wound irrigation prevent surgical site infection in
71
Dr Augustin Abraham T
General Surgery Unit II colorectal resections. CTRI/2012/12/003197 Study of transcutaneous electrical stimulation for treatment of hyper
72
Dr. Rajdeep Ojha Bioengineering
reflexive bladder dysfunction. CTRI/2012/12/003234 Uterine flushing with supernatant embryo culture medium in frozen
73
Dr Mohan S Kamath Reproductive Medicine Uthawed blastocyst transfer cycles: a randomized trial. CTRI/2013/01/003280 Does topical nitroglycerine protect the anal sphincter in patients
74
Dr. Dorcas Grace General Surgery
75
Dr. Raju Titus chacko
Medical Oncology
undergoing transanal stapled anastomosis? CTRI/2013/01/003293 A prospective, non-interventional, cohort survey on VTE risk in
patients receiving new chemotherapy for cancer CTRI/2013/02/003380 Randomized, double-blind, placebo-controlled trial to evaluate the
effects of adjunctive treatment with Aripiprazole on body weight,
metabolic parameters, clinical efficacy, and adverse events in
76
Dr Prince Rajamanickam Psychiatry
people with psychotic disorders on treatment with Clozapine CTRI/2013/02/003397 Pre treatment with antioxidants versus no treatment for male partner
in couples undergoing assisted reproductive technology (ART) for
77
Dr. Mariano Mascarenhas Reproductive Medicine Umale infertility: a randomized controlled trial. CTRI/2013/02/003431 Local endometrial injury in women undergoing repeat in-vitro
fertilization / intracytoplasmic sperm injection (IVF/ICSI)-embryo
78
Dr Aleyamma tk (ET). Reproductive Medicine Utransfer
CTRI/2013/04/003564 A direct lateral approach to the radius: A study on twenty
79
Dr Vinu M George Orthopaedics
consecutive fractures of the radius. CTRI/2013/05/003679 80
Dr Vinu M George Orthopaedics
A new method of reconstruction for long segment tibial defects
CTRI/2013/05/003675 Effect of local vibration therapy on hand function of cerebral palsy
81
Dr. Pijush Kanti Bagchi
Physiology,
children: a randomized controlled trial CTRI/2013/05/003700 A randomized controlled trial of therapeutic hypothermia for neonatal
82
Dr Niranjan Thomas Neonatology
hypoxic-ischemic encephalopathy CTRI/2013/05/003693
To study the effectiveness of spontaneous ovulation versus
ovulation triggered by human choionic gonadotropin administration
in patients undergoing intrauterine insemination in stimulated
Reproductive Medicine Ucycles. 83
Dr Sumi Thomas 84
Dr. Dhiraj John Sonbare
HPB Surgery
85
Dr. Catherine S
Obstetrics and Gynecolo Lipid profile in pregnancy and its effect on infant birth weight CTRI/2013/07/003795 Laparoscopic Intervention Vs Percutaneous Techniques for Hepatic
hydatid disease CTRI/2013/07/003844 CTRI/2013/08/003867 DOBBS SPLINT VERSUS DENNIS BROWN SPLINTS IN
86
Dr Sanjay Chilbule Paediatric orthopaedics uCONGENITAL TALIPES EQUINOVARUS CTRI/2013/11/004125 A Randomized Control Trial to evaluate the effectiveness of oral
care using tooth brush and yaunker suction compared to regular oral
care in reducing the incidence of Ventilator Associated Pneumonia
(VAP) among mechanically ventilated patients in Medical Intensive
87
Ms. Ranjitha Chacko College of Nursing
Care Units of Christian Medical college Vellore CTRI/2013/11/004158 Does Short- Term High Intensity Plyometric Training Program
improve intensity and reduce latency of Reciprocal inhibition,
increase Muscle strength, Agility and speed in untrained college
88
Dr. Anandit John Mathew
Physiology
students in an Indian population?" : A randomized controlled trial 89
DrJiji Mathews Obstetrics and Gynaecol Oral versus Vaginal misoprostol for induction of labour CTRI/2014/01/004347 CTRI/2014/02/004402 A randomized trial comparing a 30-ml and a 80-ml Foley catheter
balloon for preinduction cervical ripening for women with previous
90
Dr Jiji Mathews Obstetrics and Gynaecol LSCS requiring Induction of Labour CTRI/2014/02/004412 Intra-vaginal misoprostal versus Foley catheter for induction of
91
Dr Jiji Mathews Obstetrics and Gynaecol labour in fetus with suspected fetal compromise CTRI/2014/02/004411 Metformin vs Glyburide in gestational diabetes- A randomised
92
Dr. Jiji Elizabeth Mathews
Obstetrics and Gynaecol controlled trial CTRI/2014/02/004418 Comparison of palonosetron with ondansetron, with respect to
Dr. Narebdra Kumar
93
Chaudhary
clinical efficacy in prevention of Chemotherapy Induced Nausea and
Child Health
Vomiting in Children and Adolescents CTRI/2014/03/004492 Isometric hip and knee joint torque measurement during electrical
stimulation in order to design an FES (Functional Electrical
Stimulation) based transfer system for subjects with traumatic
94
Dr. Nissan Kunju
95
Dr. Gagandeep Kang
Bioengineeirng
complete paraplegia CTRI/2014/04/004515 Treatment of enteric infections among Indian infants to improve their
Gastrointestinal Sciencesresponse to oral poliovirus vaccine CTRI/2014/05/004588 A RANDOMIZED CONTROL TRIAL TO COMPARE THE EFFECT
OF SCALP BLOCK USING ROPIVACAINE ALONE OR
ROPIVACAINE ALONG WITH ADJUVANT DEXAMETHASONE IN
PATIENTS UNDERGOING SUPRATENTORIAL CRANIOTOMY
96
Dr. Riya Jose
Anesthesia
UNDER GENERAL ANAESTHESIA (G.A.) CTRI/2014/06/004688 Rapid tranquillization of violent or agitated patients in a psychiatric
emergency setting: Pragmatic, randomized, allocation concealed,
participant and assessor blinded trial of intramuscular zuclopenthixol
97
Dr Starlin Vijay Mythri Psychiatry
acetate versus intramuscular haloperidol plus promethazine. CTRI/2014/07/004712 Effect of Jasmine flower extract on hyperprolactinemia in female
98
Dr. Philip Finny
Endocrinology
patients on antipsychotic medications CTRI/2014/08/004829 Duration of Intestinal Immunity following Inactivated Poliovirus
99
Dr. Jacob John
Community Health
Vaccine in OPV primed children A Randomized control trial of Right Median nerve electrical
CTRI/2014/09/004979 stimulation for patients with acquired brain injury who are in
vegetative or minimally conscious state for increasing arousal and
100
Dr. Remya Mathew
Medicine and Rehabilitat responsiveness. CTRI/2014/10/005117 A randomized control trial to study the effect of a structured
Ms. Sushila Russell nee
101
Edwardraj
psychosocial intervention on the explanatory models of the primary
Child & Adolescent Psyc caregivers of children and adolescents with intellectual disability. CTRI/2014/11/005179