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 Hotel Hilton Kalastajatorppa, Helsinki, 24 ‐ 25 August 2017 Thursday 24th August 2017 9:00 REGISTRATION AND COFFEE Session 1 9:30‐9:45 Kimmo Kontula (Yrjö Jahnsson Foundation): Opening of the Symposium 9:45‐10:10 Veikko Salomaa (Helsinki, FIN): Interaction of genes and environment in pathogenesis of coronary artery disease 10:15‐10:50 Cristina Menni (London, UK): Metabolome profiling of cardiovascular diseases 11:00‐11:25 Samuli Ripatti (Helsinki, FIN): Genetics, bioinformatics and risk assessment in human cardiovascular disease 11:30‐11:55 Markus Perola (Helsinki, FIN): Epigenetic influences on risk of cardiovascular and metabolic diseases 12:00‐13:00 LUNCH Session 2 13:00‐13:35 Patricia Munroe (London, UK): Genes and environment in human hypertension 13:45‐14:20 Hitoshi Okamura (Kyoto, JAPAN): Circadian clock genes and blood pressure variation 14:30‐14:55 Jaakko Kaprio (Helsinki, FIN): Interaction of genes and smoking in human cardiovascular and metabolic diseases 15:00‐15:30 COFFEE AND REFRESHMENTS Session 3 15:30‐16:05 Stephen S. Rich (Virginia, USA): Genetic determinants of type 1 diabetes mellitus: an update 16:15‐16:40 Mikael Knip (Helsinki, FIN): Lifestyle and microbes behind beta‐cell dysfunction 16:45‐17:10 Elisabet Agardh (Lund, SWE): Epigenetic changes and diabetic retinopathy 17:15‐17:40 Per‐Henrik Groop (Helsinki, FIN): Genes and lifestyle in diabetic nephropathy 18.30 DINNER Hotel Hilton Kalastajatorppa, Helsinki, 24 ‐ 25 August 2017 Friday 25th August 2017 9:00 COFFEE Session 4 9:15‐ 9:50 Mark McCarthy (Oxford, UK): Genetic and lifestyle influences on type 2 diabetes 10:00‐10:25 Markku Laakso (Kuopio, FIN): Genetics of tissue‐specific insulin resistance 10:30‐10:55 Hannele Yki‐Järvinen (Helsinki, FIN): Clinical implications of genetics of non‐alcoholic fatty liver disease (NAFLD) 11:00‐11:25 Leif Groop (Lund, SWE): Can genetics of diabetes be translated into the clinic? 11:30‐12:30 LUNCH Session 5 12:30‐13:05 Susan Ozanne (Cambridge, UK): Developmental and nutrigenomic programming of metabolic diseases 13:15‐13:40 Hilkka Soininen (Kuopio, FIN): Genes, lifestyle and risk of Alzheimer´s disease 13.45‐14:15 COFFEE AND REFRESHMENTS 14:15‐14:40 Miia Kivipelto (Stockholm, SWE): Update on preventive measures in neurovascular and cognitive diseases 14:45‐15:15 Timo Otonkoski (Helsinki, FIN): Medicine in future: Cellular reprogramming and genome editing in metabolic diseases 15:20 ‐15:45 Aarno Palotie (Helsinki, FIN, Harvard, USA): Big data, genomics and future medicine