Classification and management of wound, principle of wound healing, haemorrhage and bleeding control 1 GYÖRGYI SZABÓ ASSISTANT PROFESSOR DEPARTMENT OF SURGICAL RESEARCH AND TECHNIQUES Basic Surgical Techniques, Faculty of Medicine, 3rd year 2021/13 Academic Year, Second Semester 2 WOUND What is a wound? 3 It is a circumscribed injury which is caused by an external force and it can involve any tissue or organ. surgical, traumatic It can be mild, severe, or even lethal. Simple wound Compound wound Acute Chronic Parts of the wound 4 Wound edge Wound corner Surface of the wound Base of the wound Cross section of a simple wound Wound edge Wound cavity Surface of the wound Base of the wound Skin surface Subcutaneus tissue Superficial fascia Muscle layer The ABCDE in the injured assessment 5 The mnemonic ABCDE is used to remember the order of assessment with the purpose to treat first that kills first. A: Airway and C-spine stabilization B: Breathing C: Circulation D: Disability E: Environment and Exposure Wound management - anamnesis 6 When and where was the wound occured? Alcohol and drug consumption What did caused the wound? The circumstances of the injury Other diseases eg. diabetes mellitus, tumour, atherosclesosis, allergy The state of patient’s vaccination against Tetanus Prevention of rabies The applied first-aid Classification of the accidental wounds 1. Based on the origine 7 I. Mechanical: 1. Abraded wound (vulnus abrasum) 2. Puncured wound (v. punctum) 3. Incised wound (v. scissum) 4. Cut wound (v. caesum) 5. Crush wound (v. contusum) 6. Torn wound (v. lacerum) 7. Bite wound (v. morsum) 8. Shot wound (v. sclopetarium) II. Chemical: 1. Acid 2. Base III. Wounds caused by radiation IV. Wounds caused by thermal forces: 1. Burning 2. Freezing V. Special Mechanical wounds 8 1.) Abraded wound (v. abrasum) 2.) Punctured wound (v. punctum) Superficial part of the epidermal Sharp-pointed object layer Good wound healing Seems negligible BUT Anaerobic infection Injury of big vessels and nerves Mechanical wounds 9 3.) Incised wound (v. scissum) 4.) Cut wound (v. caesum) Sharp object Sharp object + blunt additional Best healing force Edges - uneven Mechanical wounds 10 5.) Crush wound (v. contusum) Blunt force Pressure injury Edges – uneven and torn Bleeding 6.) Torn wound (v. lacerum) Great tearing or pulling Incomplete amputation (v. lacerocontusum) Mechanical wound 11 7.) Shot wound (v. scolperatium) Close - burn injury Foreign materials aperture output slot tunel unijured tissue necrobiotic zone necrotic zone foreign bodies Mechanical wounds 12 8.) Bite wound (v. morsum) Ragged wound Crushed tissue Torn Infection Bone fracture Prevention of rabies Tetanus profilaxis The direction of the flap 13 Distal Proximal The wound healing is good Chemical wounds 14 1.) Acid 2.) Base in small concentration – irritate in large concentration – colliquative necrosis coagulation necrosis Wounds caused by radiation 15 Symptoms and severity depend on: Amount of radiation Length of exposure Body part that was exposed Symptoms may occur immediately, after a few days, or even as long as months. What part of the body is most sensitive during radiation sickness? bone marrow gastrointestinal tract Wounds caused by thermal forces 16 1.) Burning Metabolic change! - toxemia a – normal skin 1 - 1st degree – superficial injury (epidermis) 2 – 2nd degree –partial or deep partial thickness (epidermis+superficial or deep dermis) 3 – 3rd degree – full thickness (epidermis + entire dermis) 4 – 4th degree – (skin + subcutaneous tissue + muscle and bone) Treatment: Cooling – cold water and clean covering 2.) Freezing mild, moderate, severe (redness, bullas, necrosis) rewarm – not only the frozen area but the whole body Special wounds 17 Exotic, poisonous animals Toxins, venom - toxicologist Skin necrosis Classification of the wounds 2. According to the bacterial contamination 18 Clean wound Clean-contaminated wound Contaminated wound Heavily contaminated wound Classification of the wounds 2. Depending on the depth of injury 19 Superficial Partial thickness Full thickness Deep wound + bone, opened cavities, organs…etc. source: http://www.funscrape.com/Search/1/skin+layers.html Wound management - history 20 Ancient Egypt – lint (fibrous base-wound site closure), animal grease (barrier) and honey (antibiotic) „closing the wound preserved the soul” Greeks – acute wound= „fresh” wound; chronic wound = „non-healing” wound maintaining wound-site moisture Ambroise Paré – hot oil oil of roses and turpentine, ligature of arteries instead of cauterization Lister pretreated surgical gauze – Robert Wood Johnson 1870s; gauze and wound dressings treated with iodide Applied wound management colour continuum 21 black black-yellow yellow yellow-red source: Applied wound management supplement – www.wounds-uk.com red red-pink pink Applied wound management infection continuum 22 the quantity and diversity of microbes contamination sterility critical colonisation colonisation source: Applied wound management supplement – www.wounds-uk.com infection Applied wound management exudate continuum 23 Viscosity volume high - 5 medium - 3 low - 1 high - 5 medium -3 low - 1 source: Applied wound management supplement – www.wounds-uk.com The wound managemanet 24 Temporary wound management (first aid) clean, hemostasis, covering Final primary wound management clean, anaesthesis, excision, sutures ALWAYS: thoracic cavity, abdominal wall or dura mater injury NEVER: war injury, inflammation, contamination, foreign body, special jobs, bite, shot, deep punctured wound Primary delayed suture (3-8 days) clean, wash – saline, cover excision of wound edges, sutures The wound managemanet 25 Early secondary wound closure (2 weeks) after inflammation, necrosis – proliferation anesthesia, refresh wound edges, suturing and draining Late secondary wound closure (4-6 weeks) anesthesis, scar excision, suturing, draining greater defect – plastic surgery The surgical wound 26 Surgical incision Stretch and fix Handling the scalpel Langer lines Skin edges Vessels and nerves Hemostasis Langer lines The wound edges Handling the scalpel source: http://www.medars.it/galleries/langer.htm Tissue unifying and dressing the wound 27 Skin: Stiches Clips Steri-Strips Tissue glues Fascia and subcutaneous layers: Interrupted stiches Fat – fat necrosis! Dressing: sterile, moist, antibiotic-containing, non-allergic, non-adhesive The wound healing 28 Hemostasis-inflammation Granulation-proliferation Remodelling capillaries fibroblasts lymphocytes macrophages neutrophyl gr. thrombocytes 0 1 2 3 4 5 6 7 8 9 10 11 10 13 14 15 http://www.worldwidewounds.com/2004/august/Enoch/images/enochfig1.jpg The main steps of the wound healing 29 1. Hemostasis-inflammation vasoconstriction fibrin clot formation proinflammatory citokines and growth factors releasing vasodilatation infiltration PMNs, macrophages cytokines releasing → angiogensis → fibroblast activation → B- and T-cells activation → keratinocytes activation → wound contraction 2. Granulation-proliferation fibroblast migration collagen deposition angiogensis granulation tissue formation epithelisation contraction 3. Remodelling regression of many capillaries physical contraction – myofibroblasts collagen degeneration and synthetisation new epithelium tensile strength – max. 80% Types of wound healing 30 Healing by primary intention Healing by secondary intention Healing by tertiary intention source: http://quizlet.com/13665246/chapter-3-tissue-renewal-regenerationand-repair-flash-cards/ Factors affecting wound healing 31 Local Ischemia Infection Foreign body Edema, elevated tissue pressure Systemic Hyperbaric oxygen treatment infection foreign bodies IMPAIRED HEALING edema/ elevated tissue pressure ischemia Age and gender Sex hormones Stress Ischemia Diseases Obesity Medication Alcoholism and smoking Immunocompromised conditions Nutrition Complications of wound healing I. Early complications 32 Seroma Hematoma Wound disruptin Superficial wound infection Deep wound infection Mixed wound infection Early complications of wound healing 33 1.) Seroma 2.) Hematoma Filled with serous fluid, lymph Bleeding, short drainage time, or blood Fluctuation, swelling, redness, tenderness, subfebrility anticoagulant Risk of infection Swelling, fluctuation, pain, redness TREATMENT: Sterile punture and compression Suction drain TREATMENT Sterile puncture Surgical exploration Early complications of wound healing 34 3.) Wound disruption Surgical error Increased intraabdominal pressure Wound infection Hypoproteinaemia TREATMENT: U-shaped sutures A. partial – dehiscenece B. complete - disruption Early complications of wound healing Superficial wound infection 35 1.) Diffuse 2.) Localized Located below the skin Anywhere TREATMENT Resting position Antibiotic Dermatological consultation TREATMENT Surgical exploration Drainage X-ray examination e.g. erysipelas e.g. abscess Early complications of wound healing Deep wound infection 36 1.) Diffuse 2.) Localized TREATMENT Surgical exploration Open therapy H2O2 and antibiotics Inside the tissues or body cavities e.g. anaerobic necrosis TREATMENT surgical exploration drainage Complications of wound healing I. Early complications 37 Mixed wound infection e.g. gangrene necrotic tissues putrid and anaerobic infection a severe clinical picture TREATMENT aggresive surgical debridement effective and specified (antibiotic) therapy Complications of wound healing II. Late complications 38 Hyperthrophic scar Keloid formation Necrosis Inflammatory infiltration Abscesses Foreign body containing abscesses Late complications 39 Hypertrophic scar Develop in areas of thick chorium Non-hyalinic collagen fibres and fibroblasts Confine to the incision line TREATMENT Regress spontaneously (1-2 yrs) Keloid Mostly African and Asian population Well-defined edge Emerging, tough structure Overproliferation of collagen fibers in the subcutaneous tissue Subjective complains TREATMENT Postoperative radiation Corticosteroid + local anaesthetic injection 40 BLEEDING AND HEMOSTASIS Bleeding 41 Anatomical Arterial – bright red, pulsate Venous – dark red, continuous Diffuse Capillary – can become serious Parenchymal Bleeding 42 Severity of bleeding – the volume of the lost blood and time source: http://lifeinthefastlane.com/2012/03/trauma-tribulation-025/ The direction of hemorrage 43 External Internal In a luminar organ (hematuria, hemoptoe, melena) In body cavities (intracranial, hemothorax, hemascos, hemopericardium, hemarthros) Among the tissues (hematoma, suffusion) Bleeding 44 Preoperative hemorrhage Prehospital care! – maintenance of the airways, ventillation and circulation bandages, direct pressure, turniquets Intraoperative hemorrhage anatomical and/or diffuse depending on the surgeon, the surgery, position, the size of the vessel, pressure in the vessel ANESTHESIA! Postoperative bleeding ineffective local hemostasis, undetected hemostatic defect, consumptive coagulopathy or fibrinolysis Signs of the bleeding 45 Local Hematoma, suffusion, ecchymosis Compression in the pleural cavity, in pericardium, in the skull Functional disturbancies – e.g. hyperperistalsis General Pale skin, cyanosis, decreased BP. and tachycardia, difficulty in breeding, sweeting, decreased body temperature, unconsciousness, cardiac and laboratory standstill, laboratory disorders, signs of shock Surgical hemostasis 46 Aim – to prevent the flow of blood from the incised or transected vessels Mechanical methods Thermal methods Chemical and biological methods Surgical hemostasis Mechanical methods 47 Digital pressure – direct pressure, e.g. Pringle maneuver Tourniquet Ligation Suturing Preventive hemostasis Clips Bone wax other Thermal methods 48 Low temperature Hypothermia – eg. stomach bleeding Cryosurgery dehidratation and denaturation of fatty tissue decreases the cell metabolism vasoconstriction Thermal methods 49 High temperature Electrosurgery – electrocauterization Monopolar diathermy Bipolar diathermy Laser surgery coagulation and vaporization for fine tissues Thermal methods 50 High temperature Electrocoagulation Electrofulguration (A) Electrodessication Electrosection Hemostasis with chemical and biological methods 51 vasoconstriction coagulation hygroscopic effect Absorbable collagen Absorbable gelatin Microfibrillar collagen Oxidized celluloze Oxytocin Epinephrine Thrombin Hemcon QuikClot Hemostasis with chemical and biological methods 52 HemCon
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