FlexStand Cartridge Holder - GE Healthcare Life Sciences

GE Healthcare
Instructions 18-1174-61 AC
FlexStand Cartridge Holder
Scope
This user guide describes how to assemble and use the standard FlexStand™ (FS-01S and
FS-01S-30) and the low-void-volume FlexStand (FS-03LVS and FS-03LVS-30) cartridge
holders.
Topics include:
• Product descriptions
• Assembly instructions
• Maintenance procedures.
Audience
This user guide addresses the needs of scientists, process engineers, and technicians who
operate laboratory-scale cross-flow systems. The level of information presented in this
guide assumes the user possesses basic laboratory and technical skills, and has the
knowledge and documentation to safely operate any usersupplied equipment connected
to the FlexStand cartridge holder. If you need assistance with the instructions in this guide,
contact GE Healthcare for more information.
Table of contents
1. Safety.......................................................................................................................................................................2
2. FlexStand cartridge holder ............................................................................................................................6
3. Setting up the cartridge holder ................................................................................................................ 10
4. Operation ............................................................................................................................................................ 15
5. Troubleshooting ............................................................................................................................................... 16
6. Maintenance...................................................................................................................................................... 16
7. Specifications.................................................................................................................................................... 17
8. Further information........................................................................................................................................ 18
9. Spare parts and accessories ..................................................................................................................... 19
1 Safety
Safety instructions
Everyone who works with the FlexStand cartridge holder should read, understand, and
follow the instructions in this user guide and the safety guide, Cross-Flow System Safety
Instructions. If any operator does not understand an instruction, they should stop working
with the FlexStand cartridge holder and contact GE Healthcare for guidance.
You should save the user guides and safety guide and make them available to all users of
the FlexStand cartridge holder.
Intended use
GE Healthcare designed the FlexStand cartridge holder for laboratory-scale filtration of
biological solutions using hollow fiber membrane cartridges under the conditions stated in
this user guide and the GE Healthcare cartridge operating guide. If you use the system and
cartridges in a manner not specified by GE Healthcare, you may impair the protection
provided by the system and cartridges.
When using any laboratory, pilot-scale, or production cross-flow equipment, the potential
exists for personal injury unless you follow established safety procedures. When using GE
Healthcare products, you should follow OSHA, federal, state, and local safety regulations
for equipment installation and operation. You should follow your company’s safety
regulations and good engineering practices. You should follow the specific safety
instructions provided in this user guide and any original equipment manufacturer user
guides provided with your system.
Only qualified personnel who are adequately trained and who understand the operating
instructions should install, operate, maintain, and inspect the FlexStand cartridge holder.
Operators should run water through a new system until they are familiar with its operation
and are confident the system is running properly.
2
Instructions 18-1174-61 AC
Warnings, cautions and expert advice
This user guide uses symbols and blocks of text to provide you with safety warnings and
other important information.
WARNING! A safety warning flag describes conditions or actions that can
cause bodily harm and describes how to avoid the risk.
CAUTION! A caution flag describes conditions or actions that can damage equipment and
describes how to avoid the risk.
Tip:
An expert advice flag provides you with information that can help you use your
equipment efficiently or achieve the best results.
Safety warnings
WARNING! If you overpressurize a membrane system with compressed air
during integrity testing, system components can rupture causing bodily harm.
• To avoid the rupture of a system component due to over pressurization with
compressed air, use a pressure regulator to limit the pressure of your
compressed air supply to the maximum operating pressure of your system.
•
Wear the appropriate personal protection devices when testing the system.
Instructions 18-1174-61 AC
3
WARNING! If the system leaks, it can release potentially hazardous process
fluids or cleaning fluids causing bodily harm.
• To prevent leaks and the release of potentially hazardous process or cleaning
fluids, limit feed pressure to the maximum operating pressure of your system,
periodically check parts for wear, and ensure you assemble the components
correctly.
• To monitor system pressure, GE Healthcare recommends that you install
pressure gauges on the system as described in this user guide.
• Periodically inspect the system’s gaskets, seals, and connections for wear.
Ensure you assemble the system correctly following the instructions in the
system guide.
• Wear the appropriate personal protection devices and clothing when operating
and cleaning the system. Basic personal protection devices include protective
clothing, safety glasses, and hearing protection.
• Use additional protective devices (fume hood, respirator, etc) if the nature of
your product or your company’s safety regulations require it.
WARNING! Mishandling potentially hazardous process and cleaning/storage
solutions can cause bodily harm through exposure to skin, eyes, and respiratory
system.
• To safely handle potentially hazardous process and cleaning/storage solutions,
read the MSDS for the solutions you use. Follow the handling and safety
instructions on the MSDSs and use the personal protection equipment required
by your company, local, state, and federal laws.
WARNING! Inspecting the system without disconnecting the power cable,
disconnecting the compressed air supply, and decompressing the system, can
result in bodily injury from the accidental starting of the pump or unexpected
release of pressure.
• To prevent bodily injury, disconnect the power cable, disconnect the
compressed air line, and depressurize the system before performing
inspections and disassembling the system.
4
Instructions 18-1174-61 AC
WARNING! Failure to use tubing clamps to secure tubing on tubing nipples
and hose barb fittings can cause unexpected leaks of potentially hazardous
fluids and result in bodily harm.
• To prevent unexpected leaks and possible bodily harm, use tubing clamps on
all tubing nipple and hose barb connections, particularly connections to the
feed ports for leak-free connections at high pressure.
Safety cautions
CAUTION! Hollow fiber cartridges are strong and safe, but mishandling can damage the
membrane fibers or cartridge housing connectors. Follow these guidelines to prevent
damage to the hollow fibers and cartridge housing connectors:
• If ultrafiltration hollow fibers dry out, they can be difficult to rewet. Do not
allow ultrafiltration cartridges to dry out.
• Dropping cartridges during handling or subjecting the cartridge to pressure
surges during use can damage the hollow fibers or housing. Handle cartridges
carefully to prevent dropping, and do not expose cartridges to pressure surges
during use.
• Fittings and connectors are made of plastic and can crack if clamps are
overtightened. Do not overtighten sanitary clamps when connecting fittings
and components together.
CAUTION! Failure to carefully plan the installation of the system can result in equipment
damage or poor performance. To avoid equipment damage, carefully plan the installation
of the system in reference to the effects of a power failure and utility connections. Read
the installation instructions in the system’s user guide.
Instructions 18-1174-61 AC
5
2 FlexStand cartridge holder
Package contents
The standard FlexStand cartridge holder (FS-01S) includes these items:
• Stand with supporting rods and manifolds
• 0 to 4 barg (0 to 60 psig) pressure gauge
• Backpressure control valve (tubing pinch type)
• Blank-off cap
• Six, 1.5-inch sanitary clamps
• Six, 1.5-inch sanitary gaskets (silicone)
• Tubing connector kit (KTC-2)
• Learning to Use the FlexStand Cartridge Holder user guide
• Cross-Flow System Safety: Multilingual Safety Instructions
• Certificates of compliance for FlexStand cartridge holder and components
Cartridge holder FS-01S-30 includes all the parts above, but a 2-barg (30-psig) pressure
gauge is provided in place of the 4-barg (60-psig) pressure gauge. Cartridge holder FS03LVS-30 includes all the parts below, but a 2-barg (30-psig) pressure gauge is provided in
place of the 4-barg (60-psig) pressure gauge.
The low void volume FlexStand cartridge holder (FS-03LVS) includes these items:
• Stand with supporting rods and manifolds
• 0 to 4 barg (0 to 60 psig) pressure gauge
• Backpressure control valve (tubing pinch type)
• Blank-off cap
• Six, fractional sanitary clamps
• Six, fractional sanitary gaskets (silicone)
• Tubing connector kit (KTC-FS-03VS)
• Learning to Use the FlexStand Cartridge Holder user guide
• Cross-Flow System Safety: Multilingual Safety Instructions
• Certificates of compliance for FlexStand cartridge holder and components
6
Instructions 18-1174-61 AC
System overview
A typical FlexStand cartridge holder setup showing the various components needed for
cross-flow filtration with hollow fiber cartridges (Fig 1).
1
Support rod cap
2
Support rod
3
Manifold lock knob
4
Upper (retentate) manifold
5
Cartridge (not supplied)
6
Lower (feed) manifold
7
Feed pressure gauge
8
Support rod base
9
Blank-off cap
10 Permeate line
11 Back pressure control pinch
valve
12 Secondary permeate line with
pinch clamp
Fig 1. Typical FlexStand cartridge holder.
Differences between the cartridge holders
Compared to the standard FlexStand cartridge holder (FS-01S) the low-void-volume
FlexStand (FS-03LVS) cartridge holder has smaller inside diameter manifold ports and
tubing. The standard system uses 1.5-inch sanitary connectors and the low-void-volume
system uses fractional sanitary connectors.
The main components of a FlexStand cartridge holder are:
• Supporting rods, base, and manifolds
• Pressure gauge
• Backpressure control valve
• Tubing connector kit
The following sections describe these and other key components.
Instructions 18-1174-61 AC
7
Supporting rods, base, and manifolds
The stand consists of a base plate, supporting rods, and two adjustable slider assemblies
with manifolds. The base plate holds the supporting rods which in turn support the slider
assemblies and manifolds.
The slider assemblies move up and down along the support rods and lock into positions
that enable you to mount various length cartridges between the manifolds.
The manifolds serves several functions: they direct the flow of process solution into and out
of the cartridge and they enable the attachment of the pressure gauges and process
tubing.
Pressure gauge
The FlexStand cartridge holders includes one, 0 to 4 barg (0 to 60 psig) pressure gauge to
monitor feed pressure. The mechanically dampened pressure gauge connects to the feed
and retentate ports using sanitary connectors.
You can order and mount optional pressure gauges to monitor retentate and permeate
pressure.
Backpressure control valve
The FlexStand cartridge holders include a heavy duty pinch valve that enables operators
to control the backpressure in the filtration system. The retentate tubing is placed in the
clamp and a hand knob enables operators to tighten or loosen the clamp, affecting the
backpressure on the system.
8
Instructions 18-1174-61 AC
Tubing connector kit
The standard FlexStand cartridge holder includes tubing connector kit KTC-2, and the low
void volume FlexStand includes tubing connector kit KTC-FS-03VS. The kits contain the
clamps, gaskets, and adaptors needed for assembling and operating the system (Fig 2).
Fig 2. Tubing connector kits for the standard (left) and low-void-volume (right)
Hollow fiber cartridges
You order hollow fiber cartridges separately from the FlexStand cartridge holder. Consult
our cartridge selection guide, Selecting Hollow Fiber Cartridges and Systems, for a list of
cartridges and cartridge specifications such as membrane pore sizes, fiber lumen
diameters, cartridge lengths, and membrane areas.
Instructions 18-1174-61 AC
9
3 Setting up the cartridge holder
Setting up the FlexStand cartridge holder requires choosing a location, assembling the
holder, and integrating the holder into a cross-flow filtration system and installing a
cartridge into the holder.
Choosing a location
You should locate your cartridge holder as close as possible to your cross-flow filtration
system to minimize tubing runs and hence holdup volume. The location should have
appropriate drains or collection vessels to collect waste and processed fluids. The location
should be level and sturdy. One commonly used location is on a laboratory bench near a
sink. Another is on a heavy-duty stainless steel cart or skid to enable you move the system
in and out of wet labs and cold rooms.
Unpacking
Your FlexStand cartridge holder arrives partially assembled in a single package. Carefully
remove all the components from the box. Set them out on a bench or work table and
inspect the parts for shipping damage.
Assembling the holder
The main assembly steps include these:
1 Install the support rods into the base
2
Install the feed pressure gauge
3
Install a hollow fiber cartridge
4
Connect process lines
The following sections describe each step. Consult Fig 3 as you complete the instructions.
10
Instructions 18-1174-61 AC
.
Fig 3. Typical assembly of FS-015 FlexStand cartridge holder.
Install the support rods into the base
FlexStand cartridge holders are shipped partially assembled.
1
To finish the assembly, gently lay the preassembled support rod assembly on a bench
with the manifold assemblies facing up.
2
Slide the support rods into the base plate and fasten with the supplied 5/16-inch
hexhead bolts and washers.
3
Position the FlexStand upright. If using a LABTOP rotary lobe pump, position the
FlexStand cartridge holder in front of the Labtop pump.
Instructions 18-1174-61 AC
11
Install the feed pressure gauge
Follow these steps to install the feed pressure gauge:
1 Place a 1.5-sanitary gasket on the front-facing sanitary flange of the lower manifold.
2
Hold and align the pressure gauge flange against the manifold sanitary flange and
clamp the gauge in place using a 1.5-inch sanitary clamp.
Install a hollow fiber cartridge
You can install hollow fiber cartridges with a range of pore sizes and membrane areas in
FlexStand cartridge holders:
• Cartridges with 1.5-inch sanitary flanges (standard and LVS models)
• Cartridges with fractional sanitary flanges (LVS models only)
The procedure to install each size of cartridge is described below.
Ensure you match the cartridge feed flow requirements to the
pump capacity.
Installing cartridges with 1.5-inch sanitary endfittings
(in FS-01S FlexStand holders)
For FlexStand model FS-01S, follow these steps to install a cartridge with 1.5-inch
sanitary connectors:
1 Gather these parts:
• Cartridge with 1.5-inch sanitary endfittings
• Two, 1.5-inch silicone gaskets
• Two, 1.5-inch sanitary clamps
12
2
Raise upper manifold so that distance between upper and lower manifolds exceeds
cartridge length.
3
Place a gasket on the lower manifold.
4
Place the end of the cartridge on the gasket in the lower manifold and secure with a
sanitary clamp.
5
Place a gasket on upper end of cartridge.
6
Loosen the upper manifold and slide it down to mate with gasket and upper end of
cartridge.
7
Tighten upper manifold hand knobs to secure the manifold and cartridge in place.
8
Secure the end of the cartridge to the upper manifold with a sanitary clamp.
Instructions 18-1174-61 AC
Installing cartridges with 1.5-inch sanitary endfittings
(in FS-03LVS FlexStand holders)
For FlexStand models FS-03LVS, follow these steps to install a cartridge with 1.5-inch
sanitary connectors:
1 Gather these parts:
• Cartridge with 1.5-inch sanitary endfittings
• Two, 1.5-inch silicone gaskets
• Two, 1.5-inch sanitary clamps
• Two, 1/2-inch silicone gaskets
• Two, fractional sanitary clamps
• Two, 1.5-inch-to-fractional polysulfone adaptors
2
Raise upper manifold so that distance between upper and lower manifolds exceeds the
length of the cartridge and two adaptors.
3
Place a 1/2-inch gasket on the lower manifold. Place one of the adaptors on the gasket
and manifold and secure with a sanitary clamp.
4
Place a 1.5-inch gasket on the adaptor. Place one end of the cartridge on the gasket
and adaptor and secure with a sanitary clamp.
5
Place a 1.5-inch gasket on the upper end of the cartridge. Place one of the adaptors on
the gasket and cartridge and secure with a sanitary clamp.
6
Place a 1/2-inch fractional gasket on the upper end of the adaptor. Loosen the upper
manifold and slide it down so that it mates with the gasket and adaptor.
7
Tighten upper manifold hand knobs to secure the manifold, adaptor, and cartridge in
place.
8
Secure the end of the adaptor to the upper manifold with a sanitary clamp.
Instructions 18-1174-61 AC
13
Installing cartridges with fractional sanitary endfittings
(FS-03LVS models only)
Follow these steps to install a cartridge with fractional sanitary connectors:
1 Gather these parts:
• Cartridge with fractional sanitary endfittings
• Two, 1/2-inch silicone gaskets
• Two, fractional sanitary clamps
2
Raise upper manifold so that distance between upper and lower manifolds exceeds
cartridge length.
3
Place a gasket on the lower manifold.
4
Place the end of the cartridge on the gasket in the lower manifold and secure with a
fractional sanitary clamp.
5
Place a gasket on upper end of cartridge.
6
Loosen the upper manifold and slide it down to mate with gasket and upper end of
cartridge.
7
Tighten upper manifold hand knobs to secure the manifold and cartridge in place.
8
Secure the end of the cartridge to the upper manifold with a fractional sanitary clamp.
Connect process tubing lines
Connect process tubing using the
supplied adaptors, fittings, tubing
clamp, sanitary clamps, and gaskets
(Fig 4).
There are several lines you must install:
•Feed line from the reservoir outlet to
the pump inlet
•Feed line from the pump outlet to the
feed manifold inlet
•Retentate line from the upper
manifold outlet to the feed reservoir
inlet
•Two permeate lines
•Optional diafiltrate connections to a
feed reservoir inlet
Use the appropriate adaptors and
sanitary clamps to attach your process
lines to the manifolds and cartridge
permeate ports.
Fig 4. Typical cross-flow filtration system setup.
14
Instructions 18-1174-61 AC
WARNING! Failure to use tubing clamps to secure hoses on tubing nipple and
hose barb fittings can cause unexpected leaks of potentially hazardous fluids
and result in bodily harm. To prevent unexpected leaks and possible bodily
harm, use tubing clamps on all tubing nipple and hose barb connections,
particularly connections to the feed ports for leak-free connections at high pressure.
WARNING! If the system leaks, it can release potentially hazardous process
fluids or cleaning fluids causing bodily harm. To prevent leaks and the release of
potentially hazardous process or cleaning fluids, limit feed pressure to the
maximum operating pressure of your system, periodically check parts for wear,
and ensure you assemble the components correctly.
To monitor system pressure, GE Healthcare recommends that you install pressure gauges
on the system as described in the systems’ user guides. Periodically inspect the system’s
gaskets, seals, and connections for wear.
Ensure you assemble the system correctly following the instructions in the system guide.
Wear the appropriate personal protection devices and clothing when operating and
cleaning the system. Basic personal protection devices include protective clothing, safety
glasses, and hearing protection. Use additional protective devices (fume hood, respirator,
etc) if the nature of your product or your company’s safety regulations require it.
4 Operation
The operating guide supplied with your hollow fiber cartridge describes how to use GE
Healthcare cartridges (flushing, operation conditions, cleaning, etc.) Depending upon the
type of hollow fiber cartridge you use and the process objectives, the operation of
FlexStand cartridge holder can vary considerably. If you need assistance with application
information, contact your GE Healthcare representative
Instructions 18-1174-61 AC
15
5 Troubleshooting
If the FlexStand cartridge holder does not work properly, consult Table 1.
Table 1. FlexStand cartridge holder troubleshooting guide
Symptom
Leaks at tubing nipple or hose
barb connections at
permeate ports
Possible cause
Wrong size tubing, tubing
split at hose barb, tubing
clamp not installed
Process solution leaks from
sanitary connections
Sanitary connection gasket
missing, worn, damaged,
improperly mounted, or
wrong size
Sanitary clamp loose
Corrosive process or cleaning
solution not flushed from the
surface of the holder
Stainless steel shows
evidence of corrosion
Solution
Insure tubing ID is sized
properly for the connection,
check tubing for wear or
splitting, ensure hose barb
clamp is installed and tight.
Inspect gasket for wear,
damage, and proper sizing.
Reinstall gasket.
Tighten sanitary clamp
Prevent further corrosion by
properly cleaning the
FlexStand cartridge holder
after use. Flush surface with
water and dry with a clean,
lint-free cloth.
6 Maintenance
Inspection
Periodically—based on usage—you should make these inspections:
• Check the tightness of the support rod nuts on the bottom of the base. Check the
tightness of the support rod cap. Ensure it is fully seated on the rods.
• Inspect piping connections for tightness and worn gaskets after each run.
WARNING! Inspecting the FlexStand cartridge holder without disconnecting the
feed pump power cable, disconnecting the compressed air supply, and
decompressing the system, can result in bodily injury from the accidental
starting of the pump or unexpected release of pressure.
To prevent bodily injury, disconnect the feed pump power cable, disconnect the
compressed air line, and depressurize the system before performing inspections and
disassembling the system.
16
Instructions 18-1174-61 AC
Maintenance
The system should be flushed after each use and before storage. When you flush the
hollow fiber cartridge after use, you simultaneously flush and clean the FlexStand cartridge
holder, thus no further flushing is needed.
If the last operation you perform with the cartridge holder is to flush the cartridge with a
storage solution, you must then flush the holder with DI water or WFI to remove the storage
solution. Position an old cartridge or a short piece of flexible tubing with sanitary adaptors
in the cartridge position to flush the system with water.
After use, you should wipe down the exterior components of the FlexStand cartridge holder
with water to remove dirt and residual process/cleaning solutions. Wipe the system dry
with a clean, lint-free cloth.
Storing the holder
To store the holder for more than a few days, clean it as described in the maintenance
section. Drain all rinse water from the system. Remove the cartridge from the FlexStand.
Blank off open lines or ports in the system and reservoir. Store the cartridge in accordance
with the instructions in the cartridge user guide (in general, well-sealed with ultrafiltration
membranes kept wet in storage solution) and stored at cool or ambient temperature.
System disposal
When the service life of the system is reached, flush the system to remove hazardous
process fluids. Dispose of the unit in accordance with the government and environmental
regulations that pertain to your location.
7 Specifications
Connectors, standard model
1.5-inch sanitary connectors
Connectors, low-void-volume
fractional sanitary connectors
Dimensions, approximate
(W × L × H) 25 × 30 × 112 cm (10 × 12 × 44 in.)
Weight, approximate
13.6 kg (30 lbs)
Materials of construction
316L stainless steel, anodized aluminum, rubber
Instructions 18-1174-61 AC
17
8 Further information
This user guide belongs to a set of documents that are available for GE Healthcare hollow
fiber membrane products. You can download technical documents and learn more about
hollow fiber membrane cartridges and cross-flow systems by visiting our website,
www.gehealthcare.com.
Related documents
• Selecting Hollow Fiber Cartridges and Systems
Describes the entire range of microfiltration and ultrafiltration pore sizes, cartridge
sizes and benchtop systems available from GE Healthcare. Describes how to select
cross-flow cartridges.
• Operating Guide for Hollow Fiber Cartridges and Systems
Describes operating details for hollow fiber cartridges. Includes start-up, cleaning and
storage conditions as well as autoclave procedures and chemical compatibility. An
excellent primer on the effects of concentration, time, temperature and flow rate on
membrane cartridge performance.
• Integrity Test Procedure Guide
Step by step instructions on the basic tests used to confirm membrane integrity:
pressure hold, air diffusion, bubble point and water flux.
• Validation Guide
Provides background data on materials of construction for hollow fiber membrane
cartridges. Results of USP safety tests for plastics are also included.
18
Instructions 18-1174-61 AC
9 Spare parts and accessories
Code number Model number
56-4107-54
FS-01S
56-4107-56
56-4107-57
56-4107-58
56-4107-55
56-4107-59
56-4107-63
56-4107-67
56-4107-70
56-4107-69
56-4107-62
56-4107-61
56-4107-64
56-4107-65
56-4106-03
56-4106-04
56-4106-06
56-4107-72
56-4107-73
56-4105-92
56-4105-93
Description
Standard FlexStand benchtop pilot system with
1.5-in Tri-Clamp connections
FS-02RLP
Standard FlexStand benchtop pilot system with
1.5-in Tri-Clamp connections, rotary lobe pump
FS-02RLP/50
Same as FS-02RLP except with 230-volt, 50-Hz
electrical system
FS-04LVS-RLP
Low void volume FlexStand benchtop pilot system with
fractional Tri-Clamp connections, rotary lobe pump
FS-03LVS
Low void volume FlexStand benchtop pilot system with
fractional Tri-Clamp connections
FS-04LVS RLP/50 Same as FS-04LVS-RLP except with 230-volt, 50-Hz
electrical system
TK01-30SS
Stainless steel tank, ASME code, adjustable legs,
electropolished, 30-liter capacity, sanitary ports for
retentate return, vent filter and continuous diafiltration.
Withstands up to 275°C for steam sterilization.
FRV-2A
2-liter polysulfone reservoir kit with sealable top,
autoclavable
FRV-5A
5-liter polysulfone reservoir kit with sealable top,
autoclavable
FRV-CP2-5A
Replacement cap for 2- and 5-liter polysulfone reservoirs,
autoclavable
KFSM04
Conversion kit to change standard FlexStand to low void
volume assembly
KFSM12
Conversion kit to change low void volume FlexStand to
standard assembly
KTC-2
Tubing connector kit for FS-01S
KTC-FS-03VS
Tubing connector kit for FS-03LVS
PG-TCP30
Pressure gauge, 0-2 barg (0-30 psig), mechanically
dampened, autoclavable
PG-TCP60
Pressure gauge, 0-4 barg (0-60 psig), mechanically
dampened, autoclavable
PG-TCV30P30
Vacuum pressure gauge -2 to 2 barg (-30 to 30 psig),
mechanically dampened, autoclavable
KDV-F1
Drain valve kit for FS-01S, includes custom tee, sanitary
plug valve, gasket and clamp
KPCM-1
Manual permeate control kit, includes vacuum pressure
gauge, backpressure valve, supports, adaptors, clamps
and gaskets
VDM-6SS
Diaphragm valve, fractional Tri-Clamp, stainless steel
VDM-12SS
Diaphragm valve, 1.5-in Tri-Clamp, stainless steel
Instructions 18-1174-61 AC
19
For contact information for your local
office, please visit:
www.gelifesciences.com/contact
GE Healthcare Bio-Sciences AB
Björkgatan 30
751 84 Uppsala
Sweden
www.gelifesciences.com/filtration
GE, imagination at work and GE monogram are trademarks of
General Electric Company.
FlexStand is a trademarks of GE Healthcare companies.
© 2008 General Electric Company—All rights reserved.
All goods and services are sold subject to the terms and conditions of
sale of the company within GE Healthcare which supplies them. A
copy of these terms and conditions is available on request. Contact
your local GE Healthcare representative for the most current
information.
GE Healthcare UK Ltd
Amersham Place, Little Chalfont, Buckinghamshire, HP7 9NA, UK
GE Healthcare Bio-Sciences Corp
800 Centennial Avenue, P.O. Box 1327, Piscataway, NJ 08855-1327,
USA
GE Healthcare Europe GmbH
Munzinger Strasse 5, D-79111 Freiburg, Germany
GE Healthcare Bio-Sciences KK
Sanken Bldg. 3-25-1, Hyakunincho, Shinjuku-ku, Tokyo 169-0073,
Japan
imagination at work
18-1174-61 AC 04/2008