宮崎大学学術情報リポジトリ
Title
Author(s)
プロテアーゼ活性化受容体2の生体内分布と動脈硬化発生
・進展における役割
丸塚, 浩助; 浅田, 祐士郎; 畠山, 金太; 山下, 篤
Citation
URL
http://hdl.handle.net/10458/4259
Date of Issue 2006-05
Right
Description
学術雑誌掲載論文の抜き刷りは出版社に著作権許諾が得
られていないため未掲載
平成16年度-平成17年度科学研究費補助金(基盤研究
(C))研究成果報告書
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1.
Yamashita A, Furukoji E, Marutsuka K, Hatakeyama K, Yamamoto H,
Tamura S, Ikeda Y, Sumiyoshi A, Asada Y: Increased vascular wall
thrombogenici ty combined wi th reduced blood flow promotes occ lusive thrombus
formation in rabbi t femoral artery. Arteriosclerosis, Thrombosis, and
Vascular Biology, 2004;24(12) :2420-2424.
2.
Harada-Shiba M, Takagi A, Marutsuka K, Moriguchi S, Yagyu H,
Ishibashi S, Asada Y, Yokoyama S: Disruption of autosomal recessive
hypercholesterolemia gene shows different phenotype in vitro and in vivo.
Circulat ion Research, 2004; 95 (9) :945-952.
3.
Nakamura R, Kato J, Kitamura K, Onitsuka H, Imamura T, Cao Y,
Marutsuka K, Asada Y, Kangawa K, Eto T: Adrenomedull in administration
immediately after myocardial infarction ameliorates progression of heart
failure in rats. Circulation 2004;110(4): 426-431.
4.
Kawamoto R, Hatakeyama K, Imamura T, ishikawa T, Date H, Shibata
Y, Takenaga M, Asada Y, Eto T: Relation of C-reactive protein to
restenosis after coronary stent implantation and to restenosis after coronary
atherectomy. American Journal of Cardiology, 2004;94: 104-107.
5.
Ishikawa T, Imamura T, Hatakeyama K, Date H, Nagoshi T, Kawamoto
R, Matsuyama A, Asada Y, Eto T: Possible contribution of C-reactive
protein within coronary plaque to increasing its own plasma levels across
coronary circulation. American Journal of Cardiology, 2004;93:611---614.
6.
Ishikawa T, Hatakeyama K, Imamura T, Ito K, Hara S, Date H, Shibata
Y, Hikichi Y, Asada Y, Eto T: Increased adrenomedullin immunoreactivity
and mRNA expression in coronary plaques obtained from patients with unstable
angina. Heart, 2004 ;90: 1206-1210.
7.
Tsuruda T, Kato], Cao YN, Hatakeyama K, Masuyama H, Imamura T,
Ki tamura K, Asada Y, Eto T: Adrenomedullin induces matrix
metalloproteinase-2 activity in rat aortic adventitial fibroblasts.
4
Biochemical and Biophysical Research Communications, 2004;325:
80-84.
8.
Sato Y, Hatakeyama K, Yamashi ta A, Marutsuka K, Sumiyoshi A, Asada
x.: Proportion of fibrin and platelets differs in thrombi on ruptured and eroded
coronary atherosclerotic plaques in humans.
9.
Heart, 2005; 91 (4) :526-530.
Furukoji E, Matsumoto M, Yamashi ta A, Vagi H, Sakurai Y, Marutsuka
~ Hatakeyama K, Morishita K, Fujimura Y, Tamura S, Asada Y:
Adenovirus-mediated transfer of human placental ectonucleoside triphosphate
diphosphohydrolase to vascular smooth muscle cells suppresses platelet
aggregation in vitro and arterial thrombus formation in vivo. Circulation,
2005;111(6) :808-815.
10. Hatakeyama K, Hao H, Imamura T, Ishikawa T, Shibata T, Fujimura
Y, Eto T, Asada Y: Relation of CD39 to plaque instabil i ty and thrombus
formation in directional atherectomy specimens from patients with stable and
unstable angina pectoris. American Journal of Cardiology,
2005;95(5) :632-635.
11. Sun H, Koike T, Ichikawa T, Hatakeyama K, Shiomi M, Zhang B,
Kitajima S, Morimoto M, Watanabe T, Asada Y, Chen YE, Fan J:
C-reactive protein in atherosclerotic lesions: its origin and
pathophysiological significance. American Journal of Pathology,
2005; 167 (4) : 1139-1148.
12. Tsuruda T, Kato J, Matsui E, Hatakeyama K, Masuyama H, Imamura T,
Ki tamura K, Asada Y, Eto T: Adrenomedullin alleviates not only neointimal
formation but also perivascular hyperplasia following arterial injury in rats.
European Journal of Pharmacology, 2005; 508 (1-3) : 201-204.
13. Tsuruda T, Kato J, Hatakeyama K, Masuyama H, Cao YN, Imamura T,
Kitamura K, Asada Y, Eto T: Antifibrotic effect of adrenomedullin on
coronary adventitia in angiotensin II-induced hypertensive rats.
Cardiovascular Research, 2005; 65: 921-929.
14. Hoshiba Y, Hatakeyama K, Tanabe T, Asada Y, Goto S: Co-localization
of von Willebrand factor with platelet thrombi, tissue factor and platelets
wi th fibrin, and consistent presence of inflammatory cells in coronary thrombi
5
obtained by an aspiration device from patients with acute myocardial
infarction. Journal of Thrombosis and Haemostasis, 2006;4 (1) : 114-120.
15. Nishihira K, Yamashi ta A, Tanaka N, Kawamoto R, Imamura T, Yamamoto
R, Eto T, Asada Y: Inhibi tion of 5-hydroxytryptamine receptor prevents
occlusive thrombus formation on neointima of the rabbit femoral artery.
Journal of Thrombosis and Haemostasis. 2006;4(1) :247- 255.
16. Yamashita A, Sumi T, Goto S, Hoshiba Y, Nishihira K, Kawamoto R,
Hatakeyama K, Date H, Imamura T, Ogawa H, Asada Y: Detection of von
Wi llebrand factor and tissue factor in platelets-fibrin rich coronary thrombi
in acute myocardial infarction. American Journal of Cardiology,
2006;97(1) :26-8.
17. Tsuruda T, Kato J, Hatakeyama K, Yamashita A, Nakamura K, Imamura
T, Ki tamura K, Oni tsuka T, Asada Y, Eto T: Adrenomedullin in mast cells
of abdominal aortic aneurysm. Cardiovascular Research, 2006; 70 (1) : 158
-164.
18. Kawamoto R, Yamashita A, Nishihira K, Furukoji E, Hatakeyama K,
Ishikawa T, Imamura T, Itabe H, Eto T, Asada Y: Different inflanrnatory
response and oxidative stress in neointimal hyperplasia after balloon
angioplasty and stent implantation in cholesterol-fed rabbits. Pathology
Research and Practice, 2006 (in press)
6
1.
Marutsuka K, Hatakeyama K, Yamashi ta A, and Asada Y: Role of
thrombogenic factors in the development of atherosclerosis. Journal of
Atherosc 1eros i sand Thrombos is, 2005; 12 (1) : 1-8.
2.
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1.
Marutsuka K, Hatakeyama K, Yamashita A, Moriguchi S, Sato Y, Asada
Y:
Pathophysiology of thrombogenic event in acute coronary syndrome.
The 36th Japan Atherosclerosis Society Annual Meeting. English Forum 2:
Plaque instability: From molecular mechanisms to clinical applications
(Fukuoka, 2004)
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1.
Hatakeyama K, Marutsuka K, Yamashita A, Moriguchi S, Imamura T,
Shibata Y, Fujimura Y, Asada Y: CD39 expression in human coronary
atherosclerotic lesions.
Xth Congress of the International Society of Hematology, Asian-pacific
Division (Nagoya, 2004)
2.
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Hatakeyama K, Azuma Y, Hao H, Imamura T, Nishihira K, Kawamoto R,
Shirai M, Ogawa H, Asada Y: Lack of association between Chlamydia
pneumoniae infection and plaque instability or restenosis In coronary
atherosclerotic lesion.
m69@] S *fJtU!ft~~*,.g~ (~i~" 2005)
6.
Hatakeyama K, Hao H, Imamura T, Ishikawa T, Shibata Y, Fujimura
Y, Eto T, Asada Y: Relation of CD39 to plaque instability and thrombus
formation in directional atherectomy specimens from patients wi th stable and
unstable angina pectoris.
8
7.
Nishihira K, Hatakeyama K, Imamura T, Shibata Y, Itabe H, Nakamura
H, Yodoi], Ogawa H, Eto T, Asada Y: Thioredoxin and oxidized lipoprotein
are increased in unstable plaque obtained by directional coronary atherectomy.
m69[m S *~~~~¥t~ (f1i7~, 2005)
8.
Hoshiba Y, Hatakeyama K, Asada Y, Goto S: Possible contributing role
of tissue factor and activated platelets in the formation of occlusive
fibrin-rich coronary thrombi.
m69[EI1 S *~~~~¥t~ (f1i7~, 2005)
9.
Tsuruda T, Kato ], Matsui E, Hatakeyama K, Masutyama H, Imamura
T, Kitamura K, Asada Y, Eto T: Adrenomedullin alleviates not only
neointimal formation but also perivascular hyperplasia following arterial
injury in rats.
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