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Institute for Internal Medicine, 3rd Department of Internal Medicine and
Department of Rheumatology
Subject: Clinical immunology and rheumatology
Year, semester:
2013. III/2
Number of lessons lecture:
26
practise:
18
Place of lectures:
Auguszta Lecture Hall
Educational responsible:
Dr. Zoltán Griger, Dr. György Kerekes (3rd Dept.)
Dr. Gabriella Szűcs (Dept. of Rheumatology)
Topics:
1st week
lecture:
1.
11 Feb.
Pathogenesis of autoimmune diseases. General characteristics.
11.00-12.00 Dr. Margit Zeher / Dr. Dankó Katalin
2.
14 Feb.
Non-differentiated autoimmune disease (NDC).
Mixed Connective tissue disease (MCTD).
8.00-9.00
Dr. Edit Bodolay
3.
14 Feb.
Systemic lupus erythematosus.
9.00-10.00
Dr. Tünde Tarr
practise:
Laboratory diagnosis of immunpathologic disorders.
(Laboratory of Immunology, 3rd Dept. of Int. Med.)
2nd week
lecture:
4.
18 Feb.
Raynaud’s syndrome.
11.00-12.00 Dr. Zoltán Csiki
5.
21 Feb.
Systemic sclerosis.
8.00-9.00
Dr. Gabriella Szűcs
6.
21 Feb.
Sjögren’s disease.
9.00-10.00
Dr. Antónia Szántó
practise:
Case report on SLE, NDC, MCTD. (3rd Dept. of Int. Med.)
3rd week
lecture:
7.
25 Feb.
Dermato/polymyositis.
11.00-12.00 Dr. Katalin Dankó
8.
28 Feb.
Systemic vasculitides.
8.00-9.00
Dr. Margit Zeher
9.
28 Feb.
Systemic vasculitides.
9.00-10.00
Dr. Margit Zeher
practise:
Case report of PSS and Raynaud-sy. Capillary microscopy and laser Doppler.
(3rd Dept. of Int. Med.)
4th week
lecture:
10.
4 March.
Laboratory diagnostics of allergic diseases.
11.00-12.00 Dr. Gyimesi Edit
11.
7 March
Organspecific autoimmune diseases.
8.00-9.00
Dr. Gyula Bakó
12.
7 March
Secondary immundeficiency.
9.00-10.00
Dr. Judit Végh
practise:
Case report on Sjögren´s disease and DM/PM. (3rd Dept. of Int. Med.)
1
5th week
lecture:
13.
11 March
Respiratory allergic diseases. Food allergy.
11.00-12.00 Dr. Kristóf Nékám
14.
14 March
Immunity and pregnancy. Antiphospholipid syndrome.
8.00-9.00
Dr. Antónia Szántó
15.
14 March
Tumor immunology.
9.00-10.00
Dr. Éva Zöld
practise:
Case report on vasculitis. Case report on autoimmun disease. (3rd Dept. of Int.
Med.)
6th week
lecture:
16.
18 March
11.00-12.00
17.
21 March
Immunomodulation in the treatment of autoimmune diseases.
Dr. Zoltán Griger
Introduction to rheumatology: history taking, physical exam,
diagnostics and therapy
8.00-9.00
Dr. Zoltán Szekanecz
18.
21 March
Spondylarthritides
9.00-10.00
Dr. Sándor Szántó
practise:
Physical examination. Presentation of cases with RA and other types of
arthritis (Dept. of Rheumatology)
7th week
lecture:
19.
25 March
11.00-12.00
20.
28 March
Rheumatoid arthritis
Dr. Péter Surányi
Early arthritis and special forms of RA (Felty, Caplan, juvenile
idiopathic arthritis
8.00-9.00
Dr. Andrea Váncsa
21.
28 March
Musculoskeletal rehabilitation
9.00-10.00
Dr. Zsuzsanna Veredy-Nagy
practise:
Presentation of a case with SpA, gout and other arthritides. (Dept. of
Rheumatology)
8th week
lecture:
22.
4 Apr.
Reactive and septic arthritides
8.00-9.00
Dr. János Gaál
23.
4 Apr.
Osteoporosis. Metabolic bone diseases
9.00-10.00
Dr. Andrea Váncsa
practise:
Presentation of a case with osteoporosis and osteoarthritis, low back pain.
(Dept. of Rheumatology)
9th week
lecture:.
24.
8 Apr.
11.00-12.00
25.
11 Apr.
8.00-9.00
Crystal deposition diseases
Dr. Attila Kovács
Physiotherapy and balneotherapy
Dr. Veronika Gaál
2
26.
11 Apr.
Osteoarthritis, spondylosis. Low back pain. Differential diagnosis of
arthritides and autoimmune diseases.
9.00-10.00
Dr. Szilvia Szamosi
practise:
Presentation of physiotherapy and exercise. (Dept. of Rheumatology)
Time of practises:
Monday
Tuesday
12.00-13.00
13.00-14.00
14.00-15.00
15.00-16.00
16.00-17.00
Wednesday
4, 5, 7
4, 5, 7
Thursday
9, 10, 11
9, 10, 11
1, 2, 3
1, 2, 3
Friday
6, 8
6, 8
Place of practises:
weeks 1-5: 3rd Dept of Internal Medicine
weeks 6-9: Dept. of Rheumatology
Practise leaders (weeks 1-5 – Immunology):
1.
Dr. Katalin Dankó, Dr. György Kerekes, Dr. Adrienn Szabó, Dr. Nikolett Győri
2.
Dr. Gyula Bakó, Dr. Pál Soltész, Dr. Zoltán Griger, Dr. Kata Husi
3.
Dr. Edit Bodolay, Dr. Judit, Végh, Dr. Franciska Tizedes, Dr. Ervin Sochka
4.
Dr. Zoltán Csiki, Dr. Tünde Tarr, Dr. Ervin Sochka, Dr. Borbála Székely
5.
Dr. Katalin Dankó, Dr. Franciska Tizedes, Dr. Gyöngyike Majai, Dr. L. Bodoki
6.
Dr. Edit Bodolay, Dr. Judit Végh, Dr. Katalin Veres, Dr. Melinda Nagy-Vincze
7.
Dr. Antónia Szántó, Dr. Adrienn Szabó, Dr. Kata Husi, Dr. Margit Zeher
8.
Dr. Pál Soltész, Dr. György Kerekes, Dr. Éva Zöld, Dr. Zoltán Griger
9.
Dr. Zoltán Csiki, Dr. György Kerekes, Dr. Melinda Nagy-Vincze, Dr. L. Bodoki
10.
Dr. Tünde Tarr, Dr. Gyöngyike Majai, Dr. Nikolett Győri, Dr. Margit Zeher
11.
Dr. Gyula Bakó, Dr. Antónia Szántó, Dr. Éva Zöld, Dr. Borbála Székely
Practise leaders (weeks 6-9 – Rheumatology):
Monday
Tuesday 13.00-15.00
Wednesday
Thursday 12.00-14.00
15.00-17.00
Friday 14.00-16.00
Group
4
5
7
Szamosi- Horváth
Szűcs – Soós
Bodnár - Gulyás
9
10
11
1
2
3
6
8
Váncsa - Gulyás
Bodnár - Horváth
Szántó
- Soós
Szamosi - Gulyás
Végh
- Pethő
Szántó
- Soós
Váncsa /Szűcs - Horváth
Végh - Gulyás/ Pethő
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IMMUNOLOGY
Compulsory reading:
Robert R Rich. et al.: Clinical Immunology (Principles and practice) I. II. 2008 Mosby (3rd
edition)
The Merck Manual
Offered reading:
Roitt I: Essential immunology 2011 Blackwell
Brostoff J., Scadding G.K., Male D., Roitt I.: Clinical immunology 1991 Gower Medical
Publishing
Abbas A.K., Lichtman A.H., Pober S.: Cellular and molecular immunology 2011 W.B.
Saunders Company (6th edition)
RHEUMATOLOGY
Compulsory reading:
Lecture notes
Klippel JH., Dieppe PA.: Practical rheumatology 2000 Mosby
Offered reading:
Buchanan WW., de Ceulaer K., Bálint G.: Clinical examination of the musculoskeletal system
1997 Williams and Wilkins
Requirements:
Conditions of signing the Lecture book
The student is required to attend the practices. Should they miss a practice, however, they will
be obliged to provide a well-documented reason for it. Missed practices should be made up
for at a later date, to be discussed with the tutor.
The student is expected to be able to communicate with the patient in Hungarian, including
history taking. At the end of the semester the student is required to sit the end of semester
examination (ESE). The ESE covers minimum questions (min. 85%) and all the topics of the
lectures and those in the recommended books.
Lecture download:
www.3belklinika.deoec.hu
Login:
deoec
Password:
3belklinika
www.rheumatology.hu
Login:
rheumatology
Password:
debrecen
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Titles of Clinical Immunology
1. The physiological and pathological autoimmunity.
2. General characteristics of the polysystemic autoimmune diseases.
3. Non-differentiated collagenosis (NDC).
4. The criterion-symptoms and immunologic features of the SLE.
5. The different subgroup of SLE and their characterization.
6. SLE and the gravidity.
7. Lupoid nephritis and the neurological symptoms of the SLE.
8. The treatment of the SLE.
9. The clinical and immunological features of the MCTD.
10. The therapy of the MCTD.
11. Diagnostic criterions of the Sjögren's syndrome.
12. Clinical and immunological features of the Sjögren's syndrome.
13. Pathomechanism of the vasculitis.
14. Classifications of the vasculitis.
15. Clinical symptoms and treatment of the PAN.
16. Hypersensitive vasculitis and their treatment.
17. Wegener's granulomatosis and their treatment.
18. ANCA positivity and the associated diseases.
19. The plasmapheresis as a therapeutic method.
20. Clinical symptoms of the Progressive Systemic Sclerosis (PSS).
21. The management of the PSS.
22. Dermato- Polymyositis
23. The organ specific autoimmune diseases and their features.
24. Treatment with large doses of gammaglobuline in autoimmune diseases.
25. Atopic diseases and their diagnosis.
26. Immunologic mechanism for the development of allergic diseases.
27. Tumor-associated antigens.
28. Tumor and the possibilities of the organism against of them.
29. Adoptive immunity, the formation of the tumors, immunotherapy of the tumors.
30. Respiratory allergic diseases.
31. Organ transplantation and the tissue antigens.
32. The conditions of the kidney transplantation.
33. Diagnosis and the treatment of the rejection of the transplanted kidney.
34. Characteristic of the Cyclosporin A.
35. The mechanism of action of steroids and their practical use.
36. Immunostimulant and immunomodulant.
37. Immunologic features of the gravidity.
38. Lupus anticoagulant and its practical significance.
39. Food allergy.
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Rheumatology
1. Epidemiology of rheumatic diseases.
2. Laboratory diagnosis of rheumatic diseases.
3. Imaging of rheumatic diseases
4. Rheumatoid Arthritis (RA): genetics and pathogenesis.
5. RA: Symptoms and diagnostics.
6. RA: treatment.
7. Special forms of RA (Caplan sy, Felty sy) + intermittent polyarthritis, palindrome
rheumatism
8. Juvenile chronic arthritis.
9. Ankylosing spondylitis
10. Reactive arthritis. Reiter's syndrome.
11. Psoriatic arthropathy.
12. Infectious arthritis.
13. Lyme disease.
14. Gout: classification, pathomechanism, symptoms.
15. Gout: diagnosis, associated diseases, treatment.
16. CPPD arthropathy.
17. Ostoarthritis: pathogenesis and diagnostics
18. Osteoarthritis: treatment
19. Discopathym, low back pain.
20. Osteoporosis: classification, pathomechanism, symptoms
21. Osteoporosis: diagnosis, treatment.
22. Paget's disease.
23. Humeroscapular periarthritis. Regional syndromes of the shoulder.
24. Carpal-tunnel syndrome. Entrapment syndromes.
25. Reflex sympathic distrophy (algoneurodystrophy). Aseptic bone necrosis.
26. Non-steroidal anti-inflammatory drugs (NSAIDs) in rheumatology.
27. Steroid treatment in rheumatology.
28. Physiotherapy.
29. Social and economical aspects of rheumatic diseases.
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