Emilie Vanhaecke, MA Theresa Rutchka, MS 1 To accurately diagnose a mental disorder in the context of substance use, the clinician must be able to distinguish between: 1. Primary disorders that are not etiologically related to a substance use, but may occur during substance using periods. 2. Substance induced syndromes, in which symptoms exceed intoxication or withdrawal. 3. Intoxication and withdrawal states and their relationship to the psychiatric symptoms being evaluated. 2 Substance Induced Syndromes Substance-induced delirium Substance-induced persisting dementia Substance-induced persisting amnestic disorder Substance-induced psychotic disorder Substance-induced mood disorder Substance-induced anxiety disorder Hallucinogen persisting perceptual disorder Substance-induced sexual dysfunction Substance-induced sleep disorder 1 3 What constitutes a sufficient period of abstinence? DSM-IV-TR offers a guideline of waiting 1 month after the cessation of withdrawal to diagnose a primary disorder. While establishing a sufficient period of abstinence may make a diagnosis clearer, it may not be practical, feasible, or necessary to wait for a month before assigning a diagnosis. 4 The Assessment Process Top priority when differentiating between mental health disorders and substance abuse concerns is gathering an accurate chronological history (ie. Periods of sobriety, periods of decreased on increased mental health symptoms, etc) Giving as much time as possible between getting sober and making mental health diagnoses Accepting that diagnosing is a process that occurs throughout the course of treatment and therapy 5 Dual Diagnosis Prevalence In the majority of cases, substance use/abuse exacerbates mental health symptoms and can lead to furthering the cycle of continued substance abuse and relapse of psychological symptoms Approximately 1/3 of individuals with mental illness and ½ of individuals with severe mental illness experience substance abuse Approximately 1/3 of alcohol abusers and more than ½ of drug abusers report experiencing mental illness Males are generally more likely to experience co-occurring disorders than women Other populations at higher risk for co-occurring disorders are veterans, low SES individuals, individuals with physical illness 6 Signs of Mental Illness Signs of Alcohol or Drug Abuse Difficulties at work or school Neglected appearance or dramatic change in appearance Changes in spending habits General changes in behavior Changes in physical health 7 Overlapping Symptomatology •Amphetamine Abuse • Cocaine Abuse • Alcohol Abuse • Cannabis Abuse Euphoria /Lack of Inhibition Increased Energy Memory Problems Sleep Disturbance Increased Sex Drive Insomnia Guilt /Shame Appetite Changes • Ritalin, • Adderall, etc Abuse Symptoms of Mania • Bath Salt Abuse • Opiate Abuse • Benzo Abuse Symptoms of Depression 8 Overlapping Symptomatology • Cocaine Abuse • Ampheta –mine Abuse • Stimulant Abuse • Alcohol Abuse Poor attention Memory Problems Hyper alertness Insomnia Hyper -activity Restless -ness Social Withdrawal Poor Concentration • Bath Salt Abuse Symptoms of ADHD • Ritalin, Adderall, etc. Abuse • Opiate Abuse • Benzo Abuse Symptoms of PTSD 9 Medication-Assisted Therapies These can complicate the picture of assessing and diagnosing Medication options may be limited with antagonist therapies are on board; hence the importance of referring to mental health clinicians/prescribing psychiatrists with a working knowledge of these therapies 10 Major Depressive Disorder A. Five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest of pleasure. 1. Depressed mood most of the day, nearly every day (subjective reports or observations made by others) 2. Diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day 3. Significant weight loss when not dieting or weight gain, or decrease or increase in appetite nearly every day 4. Insomnia or hypersomnia nearly ever day 5. Psychomotor agitation or retardation nearly every day 6. Fatigue or loss of energy nearly every day 7. Feelings of worthlessness or excessive or inappropriate guilt 8. Diminished ability to think or concentrate, or indecisiveness, nearly every day 9. Recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide 1 11 Major Depressive Disorder B. The symptoms do not meet criteria for a Mixed Episode C. The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. D. The symptoms are not due to the direct physiological effects of a substance or a general medication condition. E. The symptoms are not better accounted for by Bereavement, i.e. after the loss of a loved one, the symptoms persist for longer than 2 months or are characterized by marked functional impairment, morbid preoccupation with worthlessness, suicidal ideation, psychotic symptoms, or psychomotor retardation. 1 12 Major Depressive Disorder: Prevalence Major depression is one of the most common mental disorders in the United States. In 2012, an estimated 16 million adults aged 18 or older in the U.S. had at least one major depressive episode in the past year. This represented 6.9 percent of all U.S. adults. 2 13 Major Depressive Disorder: Treatment Options Medications Selective serotonin reuptake inhibitors (SSRIs) (Prozac, Paxil, Zoloft, Celexa, Lexapro) Serotonin and norepinephrine reuptake inhibitors (SNRIs) (Cymbalta, Effexor XR, Pristiq) Norepinephrine and dopamine reuptake inhibitors (NDRIs) (Wellbutrin) Atypical antidepressants (Remeron) Tricyclic antidepressants (Tofranil) Monoamine oxidase inhibitors (MAOIs) (Parnate) 2 14 Major Depressive Disorder: Treatment Options Psychotherapy Cognitive Behavioral Therapy Dialectic Behavioral Therapy Interpersonal Therapy Psychodynamic Therapy 2 15 Bipolar I Disorder Diagnosis characterized by the occurrence of one or more Manic Episodes or Mixed Episodes. Criteria for Manic Episode A. A distinct period of abnormally and persistently elevated, expansive, or irritable mood, lasting at least 1 week (or any duration if hospitalization is necessary). B. During the period of mood disturbance, three (or more) of the following symptoms have persisted (four if the mood is only irritable) and have been present to a significant degree: 1. Inflated self-esteem or grandiosity 2. Decreased need for sleep 3. More talkative than usual or pressure to keep talking 4. Flight of ideas (racing thoughts) 5. Distractibility 6. Increase in goal-directed activity or psychomotor agitation 7. Excessive involvement in pleasurable activities that have a high potential for painful consequences C. The symptoms do not meet criteria for a Mixed Episode D. The mood disturbance is sufficiently severe to cause marked impairment in occupational functioning or in usual social activities or relationships with others, or to necessitate hospitalization to prevent harm to self or others, or there are psychotic features. E. The symptoms are not due to the direct physiological effects of a substance or a general medical condition. 1 16 Bipolar I Disorder Criteria for Mixed Episode A. The criteria are met both for a Manic Episode and for a Major Depressive Episode nearly every day during at least a 1-week period. B. The mood disturbance is sufficiently severe to cause marked impairment in occupational functioning or in usual social activities or relationships with others, or to necessitate hospitalization to prevent harm to self or others, or there are psychotic features. C. The symptoms are not due to the direct physiological effects of a substance or a general medical condition. 1 17 Bipolar II Disorder Diagnosis characterized by one or more Major Depressive Episodes accompanied by at least one Hypomanic Episode. Hypomanic episodes have the same symptoms as manic episodes with two important differences: (1) the mood usually isn’t severe enough to cause problems with the person working or socializing with others (e.g., they don’t have to take time off work during the episode), or to require hospitalization; and (2) there are never any psychotic features present in a hypomanic episode. 1 18 Bipolar Disorder: Prevalence Bipolar disorder affects approximately 5.7 million adult Americans, or about 2.6% of the U.S. population age 18 and older every year. 3 19 Bipolar Disorder: Treatment Options Medications Mood stabilizers (Lithium) Anticonvulsants, utilized as mood stabilizers (Depakote, Lamotrigine, Gabapentin, Topamax, etc.) Atypical antipsychotics (Zyprexa, Abilify, Seroquel, Risperdal, etc.) Antidepressants (Prozac, Paxil, Zoloft, Wellbutrin, etc.) 3 20 Bipolar Disorder: Treatment Options Psychotherapy Cognitive Behavioral Therapy Family-focused Therapy Interpersonal Therapy Psychoeducation 3 21 Substances of Abuse That Can Cause Symptoms of Mood Disorders Major Mania/Hypomani Depression a Intoxication Withdrawal Intoxication Alcohol X X Sedative/ hypnotics X X Cocaine/crack X X X Stimulants X X X Heroin/opiates X Withdrawal Cannabis Hallucinogens X Phencyclydine (PCP) X Inhalants X X 4 22 Posttraumatic Stress Disorder Criterion A: The person was exposed to: death, threatened death, actual or threatened serious injury, or actual or threatened sexual violence, as follows: (one required) Direct exposure, witnessing in person OR Indirectly, by learning that a close relative or close friend was exposed to trauma. If the event involved actual or threatened death, it must have been violent or accidental. Repeated or extreme indirect exposure to aversive details of the event(s), usually in the course of professional duties (e.g., first responders, collecting body parts; professionals repeatedly exposed to details of child abuse). This does not include indirect non-professional exposure through electronic media, television, movies, or pictures. Criterion B: intrusion symptoms The traumatic event is persistently re-experienced in the following way(s): (one required) Recurrent, involuntary, and intrusive memories. Note: Children older than six may express this symptom in repetitive play. Traumatic nightmares. Note: Children may have frightening dreams without content related to the trauma(s). Dissociative reactions (e.g., flashbacks) which may occur on a continuum from brief episodes to complete loss of consciousness. Note: Children may reenact the event in play. Intense or prolonged distress after exposure to traumatic reminders. Marked physiologic reactivity after exposure to trauma-related stimuli. 23 Posttraumatic Stress Disorder Criterion C: avoidance Persistent effortful avoidance of distressing trauma-related stimuli after the event: (one required) Trauma-related thoughts or feelings. Trauma-related external reminders (e.g., people, places, conversations, activities, objects, or situations). Criterion D: negative alterations in cognitions and mood Negative alterations in cognitions and mood that began or worsened after the traumatic event: (two required) Inability to recall key features of the traumatic event (usually dissociative amnesia; not due to head injury, alcohol, or drugs). Persistent (and often distorted) negative beliefs and expectations about oneself or the world (e.g., "I am bad," "The world is completely dangerous"). Persistent distorted blame of self or others for causing the traumatic event or for resulting consequences. Persistent negative trauma-related emotions (e.g., fear, horror, anger, guilt, or shame). Markedly diminished interest in (pre-traumatic) significant activities. Feeling alienated from others (e.g., detachment or estrangement). Constricted affect: persistent inability to experience positive emotions. 24 Posttraumatic Stress Disorder Criterion E: alterations in arousal and reactivity Trauma-related alterations in arousal and reactivity that began or worsened after the traumatic event: (two required) Irritable or aggressive behavior Self-destructive or reckless behavior Hypervigilance Exaggerated startle response Problems in concentration Sleep disturbance Criterion F: duration Persistence of symptoms (in Criteria B, C, D, and E) for more than one month. Criterion G: functional significance Significant symptom-related distress or functional impairment (e.g., social, occupational). Criterion H: exclusion Disturbance is not due to medication, substance use, or other illness. 25 Posttraumatic Stress Disorder: Prevalance 7-12% of individuals will experience it at some point in their lifetime Over 50% comorbidity with alcohol abuse; Over 30% comorbidity with drug abuse Women more likely to develop PTSD Men more likely to abuse alcohol specifically 26 PTSD and Substance Abuse: A Vicious Cycle Similar endorphin rush from alcohol that comes from the body coping with a stressful moment; Endorphin withdrawal similar to alcohol withdrawal Substances (often depressants) often used to “numb” the anxiety and hypervigilance of PTSD; however, substance use worsens the feelings of fear and anxiety in withdrawal Stimulants being seen as a way to cope with the “numbing” symptoms of PTSD Substances often used to cope with flashbacks and nightmares Increased risk of relapse in individuals in recovery 27 PTSD: Treatment Options Cognitive-Behavioral Therapy Psychoeducation (for the individual, and family/support system highly encouraged) Family Therapy EMDR (Eye Movement Desensitization and Reprocessing) Group psychotherapy (including models such as Seeking Safety, support groups, etc.) Antagonist medications indicated as potentially helpful SSRI’s may be effective in treating certain symptoms such as avoidance/numbing symptoms Benzodiazepines have historically been prescribed but they are not recommended for long term treatment due to high abuse potential 28 Attention-Deficit/Hyperactivity Disorder Inattention: Six or more symptoms of inattention for children up to age 16, or five or more for adolescents 17 and older and adults; symptoms of inattention have been present for at least 6 months, and they are inappropriate for developmental level: Often fails to give close attention to details or makes careless mistakes in schoolwork, at work, or with other activities. Often has trouble holding attention on tasks or play activities. Often does not seem to listen when spoken to directly. Often does not follow through on instructions and fails to finish schoolwork, chores, or duties in the workplace (e.g., loses focus, side-tracked). Often has trouble organizing tasks and activities. Often avoids, dislikes, or is reluctant to do tasks that require mental effort over a long period of time (such as schoolwork or homework). Often loses things necessary for tasks and activities (e.g. school materials, pencils, books, tools, wallets, keys, paperwork, eyeglasses, mobile telephones). Is often easily distracted Is often forgetful in daily activities. 29 Attention-Deficit/Hyperactivity Disorder Hyperactivity and Impulsivity: Six or more symptoms of hyperactivity-impulsivity for children up to age 16, or five or more for adolescents 17 and older and adults; symptoms of hyperactivity-impulsivity have been present for at least 6 months to an extent that is disruptive and inappropriate for the person’s developmental level: Often fidgets with or taps hands or feet, or squirms in seat. Often leaves seat in situations when remaining seated is expected. Often runs about or climbs in situations where it is not appropriate (adolescents or adults may be limited to feeling restless). Often unable to play or take part in leisure activities quietly. Is often "on the go" acting as if "driven by a motor". Often talks excessively. Often blurts out an answer before a question has been completed. Often has trouble waiting his/her turn. Often interrupts or intrudes on others (e.g., butts into conversations or games) In addition, the following conditions must be met: Several inattentive or hyperactive-impulsive symptoms were present before age 12 years. Several symptoms are present in two or more setting, (e.g., at home, school or work; with friends or relatives; in other activities). There is clear evidence that the symptoms interfere with, or reduce the quality of, social, school, or work functioning. The symptoms do not happen only during the course of schizophrenia or another psychotic disorder. The symptoms are not better explained by another mental disorder (e.g. Mood Disorder, Anxiety Disorder, Dissociative Disorder, or a Personality Disorder). 3 Subtypes 30 ADHD: Prevalence Up to 5% of children in the general population meet criteria for ADHD Between 30% and 50% carry their symptoms into adulthood According to a study done by the U.S. Department of Health and Human Services: Teens with ADHD are twice as likely to have gotten drunk in the past six months. Teens with ADHD are more likely to try alcohol or drugs at a younger age. Teens with ADHD are more likely to use multiple illegal drugs. Teens with ADHD are more likely to use marijuana. 31 ADHD and Stimulant Treatment Recovery and ADHD treatment can be difficult due to the fact that ADHD is commonly treated with habit-forming medication with a high potential for abuse. However, many individuals who are diagnosed with ADHD can be less likely to relapse once their symptoms are being properly medicated. To determine effectiveness, option of a “drug holiday” Option of looking into extended release or longer acting stimulant medications for those individuals struggling with substance abuse. Research suggests medication in combination with psychotherapy is more effective for individuals with ADHD. 32 ADHD Treatment Methylphenidate (Ritalin, Concerta, Metadate, Methylin, etc.) Amphetamines (Dexedrine, Dextrostat, Adderall, etc.) Non-stimulant medications include Strattera (atomoxetine, a selective norepinephrine reuptake inhibitor) and Vyvanse (lisdexamfetamine dimesylate) At times – antidepressants Medication Cognitive-behavioral therapy Psychoeducation Behavioral Therapy Social Skills Training (in both children, and in adults who may have self-medicated with other substances Therapy 33 Borderline Personality Disorder Borderline Personality Disorder is a pervasive pattern of instability of interpersonal relationships, self-image, and affects, and marked by impulsivity beginning by early adulthood and present in a variety of contexts, as indicated by five (or more) or the following: 1. Frantic efforts to avoid real or imagined abandonment 2. A pattern of unstable and intense interpersonal relationships characterized by alternating between extremes of idealization and devaluation 3. Identity disturbance: markedly and persistently unstable self-image or sense of self 4. Impulsivity in at least two areas that are potentially self-damaging (spending, sex, substance abuse, reckless driving, binge eating, etc) 5. Recurrent suicidal behavior, gestures, or threats, or self-mutilating behavior 6. Affective instability due to a marked reactivity of mood 7. Chronic feelings of emptiness 8. Inappropriate, intense anger or difficulty controlling anger 9. Transient, stress-related paranoid ideation or severe dissociative symptoms 1 34 Borderline Personality Disorder: Prevalence In 2008, the first-ever large-scale, community study of personality disorders found a lifetime prevalence of 5.9 percent (18 million people) for BPD, with no significant difference in the rate of prevalence in men (5.6 percent) compared with women (6.2 percent). The authors concluded, “BPD is much more prevalent in the general population than previously recognized, is equally prevalent among men and women, and is associated with considerable mental and physical disability, especially among women.” 5 35 Borderline Personality Disorder: Stigma Individuals with a diagnosis of BPD are subject to a great deal of discrimination and bias, both in society at large and within the mental health treatment community. Paris wrote: Patients with borderline personality disorder (BPD) …. can challenge even the most experienced therapists. The most frightening symptoms of BPD are chronic suicidal ideation, repeated suicide attempts, and self-mutilation. These are the patients we worry about— and are afraid of losing. …All too frequently, [BPD] is diagnosed as a variant of major depression or bipolar disorder. Moreover, patients with BPD are often mistreated. They receive prescriptions for multiple drugs that provide only marginal benefit. They do not always get the evidence-based psychotherapy they need. 6 36 Borderline Personality Disorder: Treatment Options SAMHSA’s National Registry of EvidenceBased Programs and Practices (NREPP) lists two evidence-based practices for this disorder: dialectical behavior therapy and psychoeducational multifamily groups. DBT is a type of cognitive-behavior therapy pioneered by Marsha Linehan in the early 1990s. It combines weekly individual therapy with weekly group skills training in mindfulness (i.e., awareness of present experiences), distress tolerance, emotion regulation, and interpersonal effectiveness over a period of at least 12 months. 5 37 A Note On Anxiety Disorders Is it organic anxiety? Or a natural and expected adjustment period in recovery of developing new coping skills? 38 DSM 5 Screening Tools Psychiatry.org now offers numerous APA approved DSM 5 screening measures for clinicians geared towards narrowing the scope of the assessment process Numerous measures offered for: Depression Drug and alcohol use Mood disorders Anxiety disorders Trauma screening Suicide Risk 39 Promoting Treatment When promoting treatment adherence and motivation for change – important to listen to the client’s priorities IE. Does the client want relief from their depression more than they want to acknowledge a substance use problem? Does the client prioritize their sobriety over exploring mental health treatment? 40 Examples to Work Through 41 References 1. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: American Psychiatric Association. 2. National Institute of Mental Health. (2015). Major Depression Among Adults. Retrieved from http://www.nimh.nih.gov/health/statistics/prevalence/major-depressionamong-adults.shtml 3. National Institute of Mental Health. (2015). Bipolar Disorder. Retrieved from http://www.nimh.nih.gov/health/topics/bipolardisorder/index.shtml 4. Miele, G.M., Trautman, K.D., Hasin, D.S. (1996). Assessing Comorbid Mental and Substance-Use Disorders: A Guide for Clinical Practice. Journal of Psychiatric Practice, 276. Retrieved from http://www.columbia.edu/~dsh2/prism/files/miele.pdf 5. U.S. Department of Health and Human Services. Report to Congress on Borderline Personality Disorder. Retrieved from https://store.samhsa.gov/shin/content/SMA11-4644/SMA11-4644.pdf 42 References 6. Paris, J. (2008). Treatment of borderline personality disorder: A guide to evidence-based practice. New York: Guilford Press. 7. Brady, K.T., Back, S.E., & Coffey, S.F. (2004). Substance abuse and posttraumatic stress disorder. Current Directions in Psychological Science, 13, 206-209. 8. Kessler, R.C., Sonnega, A., Bromet, E., Hughes, M., & Nelson, C.B. (1995). Posttraumatic stress disorder in the National Comorbidity Survey. Archives of General Psychiatry, 52, 1048-1060. 9. Tull, M.T., Baruch, D., Duplinsky, M., & Lejuez, C.W. (in press). Illicit drug use across the anxiety disorders: Prevalence, underlying mechanisms, and treatment. In M.J. Zvolensky & J.A.J. Smits (Eds.), Health behaviors and physical illness in anxiety and its disorders: Contemporary theory and research. New York, NY: Springer. 10. Mayo Clinic. (2015). Posttraumatic Stress Disorder (PTSD). Retrieved from http://www.mayoclinic.com/health/posttraumatic-stress-disorder/DS00246 43 References 11. Copeland, M.E., and M. Harris. (2000) Healing the trauma of abuse; A woman’s workbook. Oakland, CA: New Harbinger. 12. Behavioral Health Evolution. (2015). Dual Diagnosis. Retrieved from http://www.bhevolution.org/public/cooccurring_disorders.page 13. Mayo Clinic. (2015). Drug addiction symptoms. Retrieved from http://www.mayoclinic.org/diseases-conditions/drugaddiction/basics/symptoms/con-20020970. 14. Substance Abuse and Mental Health Services Administration. (2015). Integration of mental health. Retrieved from http://media.samhsa.gov/co-occurring/topics/healthcareintegration/index.aspx 15. National Center for Biotechnology Information. (2015). The assessment process. Retrieved from http://www.ncbi.nlm.nih.gov/books/NBK64196/. 44
© Copyright 2024