Dengue deaths and age–sex specific laboratory confirmed infections for the years 2006–2014 in Pakistan: A systematic analysis for the dengue burden Prof. Saleem M. Rana PhD, FRSE Contech International School of Public Health Lahore, Pakistan • Up-to-date evidence on levels and trends for age-sex-specific mortality due to dengue infections is essential for the formation of health policies. • We estimated mortality and prevalence due to Dengue age-sex-specific for all areas of Pakistan between 2006 and 2014 applied to an updated database. We found the rapid increase in annual incidence and spread geographically. • To see the situation, we took into account trends for key covariates that explained changes in age-specific rates, recent global and national changes and reviewed the data to develop a precise estimates of dengue causes of deaths and rapid spread for Pakistan and prediction of future 2015 deaths and infections. Courtesy: Institute of Health Metrics and Evaluation, University of Washington Number of Deaths in Pakistan 300 285 250 222 219 200 150 131 100 50 41 40 18 17 13 2007 2008 2009 14 0 2006 2010 2011 2012 2013 2014 2015 Courtesy: Electronic Complaint Routing System|ecrs.punjab.gov.pk/phl_cms Sex wise Laboratory Confirmed Cases in Pakistan Year wise geographical spread of Dengue in Punjab All age moderate Dengue Infections Post-dengue chronic fatigue cases Severe dengue cases Global WORK PACKAGES Dengue surveillance WP1 Integrated surveillance and early warning systems WP2 Novel diagnostic assays for resource limited settings WP3 Novel tools for vector Surveillance WP9 Research conduct data management and modelling Prevention of dengue in children Risk of dengue introduction to uninfected areas WP4 Novel strategies to prevent Dengue in school children Impregnated school uniforms: a randomized control trial WP5 Repellent efficacy of impregnated uniforms Cross-cutting WP10 Geo-spatial modelling and risk maps WP12 Management and Dissemination WP6 Sentinel surveillance of imported dengue : trends and virus evolution WP7 Surveillance and control of Aedes WP8 Climate change, global mobility and population dynamics: predictive models WP11 Economic evaluation and evidenceinformed policy making Way Forward • Innovative tools are required to respond and achieve better: – predictive models – prevention, – surveillance, – diagnosis, – monitoring *in the context of globalization and climate change