Wyss Family Symposium on Genetic Predisposition to Brain Cancer May 11–12, 2015 Wyss Family Symposium on Genetic Predisposition to Brain Cancer May 11–12, 2015 Hilton Columbus Downtown Faculty Keynote: Carlo M. Croce, MD Distinguished University Professor The John W. Wolfe Chair in Human Cancer Genetics Professor and Chair, Department of Molecular Virology, Immunology and Medical Genetics Director, Human Cancer Genetics Program Director, Genetics Institute Shahab Asgharzadeh, MD Jonathan L. Finlay, MB, ChB Division of Hematology/Oncology Associate Professor of Pediatrics Children’s Hospital Los Angeles Professor of Pediatrics The Ohio State University Director, Neuro-Oncology Program Division of Hematology/Oncology/BMT Nationwide Children’s Hospital Jeffrey R. Leonard, MD Russell R. Lonser, MD Conference Hosts Nationwide Children’s Hospital Division of Hematology, Oncology and BMT Nationwide Children’s Hospital Division of Neurology Nationwide Children’s Hospital Personalized Medicine and Cancer Predisposition Program David H. Gutmann, MD, PhD Department of Neurology Director, Neurofibromatosis Center Washington University School of Medicine Chief, Pediatric Neurosurgery Nationwide Children’s Hospital Professor of Clinical Neurosurgery The Ohio State University College of Medicine David Malkin, PhD Donald W. (“Will”) Parsons, MD, PhD Professor and Chairman Department of Neurological Surgery The Ohio State University Intended Audience: Adult and pediatric neurosurgeons, pediatric and medical neuro-oncologists and oncologists, neuro-radiologists, internists, pediatricians, geneticists, genetic counselors, at-risk families, and other pertinent healthcare providers. Conference Planning Committee Daniel E. Barr, MHSA, FACHE Elena Chiappinelli, MSW, MHA Tami Davis Jennifer English Jonathan Finlay, MB, ChB Elizabeth Potts Steve Roach, MD Elizabeth Varga, MS, LGC Tammi Young-Saleme, PhD Professor of Pediatrics and Medical Biophysics University of Toronto Director, Cancer Genetics Program Senior Staff Oncologist, Division of Hematology/Oncology Senior Scientist, Genetics and Genome Biology Program The Hospital for Sick Children Joshua D. Schiffman, MD Medical Director, High Risk Pediatric Cancer Clinic Associate Professor, Pediatric Hematology/Oncology Adjunct Associate Professor, Oncological Sciences Investigator, Huntsman Cancer Institute Assistant Professor, Baylor College of Medicine Departments of Pediatrics, Molecular & Human Genetics Texas Children’s Cancer Center Uri Tabori, MD Associate Professor of Pediatrics, Institute of Medical Sciences, UofT Staff Neuro-Oncologist at The Hospital for Sick Children Senior Scientist and Principal Investigator, Genetic & Genomic Program, Research Institute The Hospital for Sick Children Steve Roach, MD Chief of Pediatric Neurology Vice-Chair of Pediatrics Nationwide Children’s Hospital Professor of Pediatrics and Neurology The Ohio State University College of Medicine Andrea F. Patenaude, PhD Associate Professor, Department of Psychiatry, Harvard Medical School Director of Psycho-Oncology Research in the Division of Pediatric Oncology, Dana-Farber Cancer Institute Agenda Wyss Symposium on Genetic Predisposition to Brain Cancer May 11-12, 2015 Hilton Columbus Downtown Monday, May 11, 2015 7 – 8 a.m.Breakfast and Check-in 8 – 8:05 a.m. Introduction Dr. John Barnard 8:05 – 8:10 a.m. Introduction 8:10 – 8:30 a.m. Overview 8:30 – 9:05 a.m. Neurofibromatosis - Type 1 9:05 – 9:15 a.m. 9:15 – 9:50 a.m. Questions Neurofibromatosis - Type 2 9:50 – 10 a.m. Questions 10 – 10:35 a.m. Tuberous Sclerosis Complex 10:35 – 10:45 a.m. 10:45 – 11:15 a.m. Mr. Oliver Wyss Dr. Jonathan Finlay Dr. David Gutmann Dr. Jeffrey Leonard Dr. Steve Roach Questions Break 11:15 a.m. – 12 p.m. Keynote Address: Micro RNAs in Cancer Genetics Dr. Carlo Croce 12 – 12:10 p.m. Questions 12:10 – 12:45 p.m.Von Hippel Lindau Syndrome Dr. Russell Lonser 12:45 – 1 p.m. Questions 1 – 2:30 p.m. Lunch Family Symposium Hilton Columbus Downtown Monday, May 11, 2015 1:30 – 2:30 p.m.Check-in for Families 2:30 – 2:40 p.m. Mr. Oliver Wyss 2:40 – 2:55 p.m. Overview Dr. Jonathan Finlay 2:55 – 3:10 p.m. The Family Centric Cancer Genetics Clinic 3:10 – 3:25 p.m. Advances in Understanding of Neurocutaneous Syndromes 3:25 – 3:40 p.m. Advances in Understanding of Cancer Predisposition Syndromes 3:40 – 3:55 p.m. Psychological Issues Confronting At-Risk Families 3:55 – 4:25 p.m. 4:25 – 4:40 p.m. Break The Pros & Cons of Genomic Screening 4:40 – 5:15 p.m. Round Table Questions 5:15 – 5:20 p.m. Adjourn 6:30 p.m. + Symposium Banquet Dr. Joshua Schiffman Dr. Steve Roach Dr. David Malkin Dr. Andrea Patenaude Dr. Will Parsons Drs. Finlay, Roach, Schiffman, Malkin, Parsons & Patenaude Tuesday, May 12, 2015 7:30 – 8 a.m.Breakfast and Check-in 8 – 8:35 a.m. Mismatched Repair Syndrome Dr. Uri Tabori 8:35 – 8:45 a.m. Questions 8:45 – 9:20 a.m. Li Fraumeni Cancer Predisposition Syndrome Dr. David Malkin 9:20 – 9:30 a.m. 9:30 – 10:05 a.m. Questions The Family Centric Cancer Genetics Clinic 10:05 – 10:15 a.m. 10:15 – 10:50 a.m. Questions Psychological Issues Confronting At-Risk Families 10:50 – 11 a.m. 11 – 11:15 a.m. uestions Q Break 11:15 – 11:50 a.m. Bioinformatic Perils of Cancer Genomics Dr. Joshua Schiffman Dr. Andrea Patenaude Dr. Shahab Asgharzadeh Conference Registration Attendees may register via the web at www.nationwidechildrens.org/ wyss-family-symposium or Nationwidechildrens.org/courses-conferences. Upon receipt of registration payment, each participant registering before May 1, 2015 will receive a confirmation letter via email. The registration fee includes the educational materials, which will be provided on a flash drive, breakfast, lunch and afternoon refreshments. Dinner registration fee is separate from the conference registration, but may be combined with the conference payment. Physician – $175 Nationwide Children’s Physician – $125 Non-Physician Staff – $100 Nationwide Children’s Non-Physician Staff – $75 Residents, Fellows – Complimentary Patient/Family Members – Complimentary Students – Complimentary 11:50 a.m. – 12 p.m. Questions 12 – 12:35 a.m. Cancer - Genome Analysis Dinner Day 1 – $60 (patient/family attendees complimentary) Late fee after May 1, 2015 – $25 (additional to registration) Dr. Will Parsons 12:35 – 12:45 p.m. Questions Conference and Hotel Accommodations 12:45 – 1:15 p.m. Lunch and Adjourn Hilton Columbus Downtown 401 North High Street Columbus, OH 43215 www3.hilton.com Enjoy a refreshing and comfortable stay in the Hilton Columbus Downtown hotel located in the heart of Columbus and near the Arena District, the Short North and the North Market. Relax and refresh in a comfortable modern guest room. Unwind with your favorite show on a 42-inch flat-screen TV and select from a range of premium TV channels. Catch up with work at the desk and benefit from high-speed internet access to keep in touch with family and business. Unwind after a day of business or sightseeing on a comfortable king- or queen-sized bed. Upgrade to a spacious suite with a separate sleeping area or indulge in a stylish Executive room. Executive room guests enjoy access to the executive lounge with complimentary breakfast and additional food and drinks. Meet friends for lunch or dinner and select from a diverse range of tantalizing cuisine in the inviting Gallerie Bar & Bistro. Enjoy a selection of tasty snacks and meals in the beautiful atrium setting. Maintain your fitness routine during your stay with an energizing workout in the fitness center, and enjoy a refreshing swim in the indoor pool. Make business easy in the 24-hour business center featuring a range of business-friendly facilities. Hold business meetings, conferences and elegant weddings in a choice of versatile meeting rooms accommodating any size of event. The Greater Columbus Convention Center provides extra meeting space and is linked to the hotel by a glass skywalk. Airport Port Columbus International Airport, located just 10 minutes from the Hilton Columbus Downtown, is served by 10 airlines and their regional affiliates providing 350 daily arrivals and departures to 35 airports. Major carriers include AirTran, Air Canada Express, American, Delta, Southwest, United and US Airways. All ground transportation may be accessed via the terminal walkway or baggage claim level exits. Taxi service is provided by many vendors. The average fare from Port Columbus International Airport to the Hilton Columbus Downtown is $35-$40. Cancellation Policy A refund, minus 30% for administrative costs, will be given for cancellations received in writing before May 1, 2015. After this date, no refunds will be available. Faculty Disclosure of Commercial Relationships Consistent with ACCME guidelines, planning committee members and faculty for this conference are expected to disclose all relevant financial relationships with any commercial interests in the last 12 months that create, or may be perceived as creating, a conflict related to the material discussed. Any relationships identified will have been resolved prior to the delivery of the educational activity. Full disclosure of relationship(s) and steps taken to resolve (when relevant) will be made prior to the presentations. Continuing Education Physician – The Nationwide Children’s Hospital is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Nationwide Children’s Hospital designates this live activity for a maximum of 8.0 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Psychology – Please call (614) 355-0676 for information about psychology CE credit for this conference. Questions? Nationwide Children’s Hospital Education Professional Conferencing 700 Children’s Drive Columbus, OH, 43205 Phone (614) 355-0676 | FAX (614) 355-0670 NationwideChildrens.org/wyss-family-symposium 10200 Nationwide Children’s Hospital 700 Children’s Drive Columbus, Ohio 43205 PERMIT NO. 777 NONPROFIT ORG. U.S. POSTAGE PAID COLUMBUS, OH
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