Up to 80% of asthmatic patients Asthma Triggers Indoor Allergy = Constant Allergy also have allergic rhinitis. 1 Dust Mites Pollens Molds Air Pollution Pets Tobacco Smoke Connecting Allergy & Asthma Figure 1. Allergy symptoms are major risk factors for the development of asthma. Asthma is currently diagnosed in about 8% of the population and consistently higher in children.2 Recognition of asthma symptoms or the warning signs of later asthma symptoms is often hard to do and frequently missed.2 Medical costs for asthma are approximately $30 billion per year in the US2 The presence of allergens in your environment can cause an asthma attack. Research has shown that allergy and asthma are closely related diseases.1, 2, 3 This is because all parts of the airway are connected. What causes problems in one part of the airway, such as the nose, can have a direct impact on other parts, such as the lungs. Continuous exposure to common indoor allergens, such as dust mite, can lead to constant inflammation, or swelling, in the airway.4 This constant swelling in the airway can make your asthma symptoms worse. While seasonal allergens, such as pollen, can also trigger asthma symptoms, these have less of an overall impact since their exposure usually lasts for shorter periods of time. Am I Really Fine? With constant exposure to indoor allergens, airway inflammation may be present without any perceived symptoms. Research shows that physical allergy signs, such as inflammation of the nose, were found in many asthma patients who reported having no allergy symptoms.5 This is a problem because both allergy and asthma require long term treatment. When patients think they are getting better they often stop taking their medications. But this can often lead to the worsening of symptoms over time. When diagnosing allergy, it is important that your doctor evaluate your lung function for signs of developing asthma.2 Likewise, when diagnosing asthma, it is important that your doctor move beyond the lungs and evaluate your allergy symptoms. The best treatment addresses both conditions to improve the overall health of your airway. It has been found that patients with poorly controlled allergy symptoms have more severe asthma attacks that get worse over time.1 In general, the more persistent and intense your allergy symptoms, the more likely asthma will develop, or get worse. This is especially true of children. Research has shown that If you’re an asthma patient that requires daily medication, you should consider being evaluated for allergy.6 By diagnosing and treating your allergies early, you can remove a common trigger of asthma symptoms. allergy and asthma are closely related diseases. Combining Allergy & Asthma Treatment Corticosteroid inhalers are the most common treatment for asthma. They reduce airway swelling and result in better control of symptoms. Despite their effectiveness, however, they must be used regularly and do not provide a cure for asthma. The regular, long term use of asthma medication can be expensive. Average medical costs for an asthma patient are $1300 per year.2 These costs get even higher in asthma patients who have significant allergy symptoms. By treating allergy, your asthma symptoms may become less severe and the overall cost of treatment may decline.7 This is why it is important to consider combining standard asthma treatment with an allergy treatment. While using allergy medications can be helpful, these only cover up symptoms.3 Treating the underlying cause of your allergy with allergy immunotherapy (allergy shots) may provide more long lasting relief. Please refer to reverse side of this brochure for the risks and warnings associated with Allergy Immunotherapy. Allergy Immunotherapy for Asthma Patients Allergy immunotherapy works by reducing your body’s allergic response to specific allergy triggers and is a clinically proven treatment that can significantly reduce allergic symptoms. In clinical studies, asthma patients who received allergy immunotherapy in addition to standard asthma treatment reported fewer asthma symptoms, required less asthma medication, and demonstrated improved lung function compared to those receiving standard asthma treatment alone.8, 9 Can Allergy Immunotherapy Prevent Developing Asthma? Yes. Research shows that in some vulnerable allergic patients, allergy immunotherapy can alter the progression of disease and prevent the development of asthma.10 Indications for Treatment with Allergy Immunotherapy Indications for allergy immunotherapy treatment in allergic asthma include the presence of a clinically diagnosed allergic condition; side effects or suboptimal control with medications; patient’s desire to avoid long term medication use; and/or ineffectiveness of environmental control measures. Asthma patients on daily medication should consider being evaluated for allergy. This information is sponsored through an educational grant by: 1700 Royston Ln • Round Rock, TX 78664 800-325-7354 www.alk-abello.us S511v2 Resources: 1. Vinuya, R. Ann Allergy Asthma Immunol 2002;88(Suppl):8-15 2. Krouse, J, et al. OTO – Head & Neck Surgery 2007;136:S75-S106 3. Serrano, C, et al. Arch Bronconeumol 2005;41(10):569-578 4. Gaffin, J, & Phipatanakul, W. Curr Opin Allergy Clin Immunol 2009;9(2):128-135 5. Ricca, V, et al. J Allergy Clin Immunol 1999;104:54-57 6. Platts-Mills, T, et al. Am Fam Physician 2007;76:675-680 7. Passalacqua, G, & Durham, S. J Allergy Clin Immunol 2007;119:881-891 8. Abramson, M, et al. Allergy 1999;54:1022-1041 9. Ross, R, et al. Clin Ther 2000;22:329-341 10. Jacobsen, L, et al. Allergy 2007;62:943-948 Cautions Uncontrolled asthma is a risk factor for adverse reactions to allergy shots. Asthma should be controlled at the time of injection. Patients with severe or uncontrolled asthma may not be appropriate candidates for allergy immunotherapy. Ask your doctor if you are a candidate for this treatment. Long lasting, severe asthma can lead to physical changes in the lungs that may reduce the benefits of allergy immunotherapy and increase the risks.9 This demonstrates the importance of early detection and early intervention. Allergy immunotherapy is a long term investment in your health that requires dedication and consistency to achieve the full benefits. While symptom relief can be achieved in the first few months of treatment, studies have shown that it takes a commitment of 3-5 years to achieve the full, long lasting effects. Risks and Warnings for Immunotherapy Allergy Immunotherapy (allergy shots) is a treatment for patients exhibiting allergic reactions to seasonal pollens, dust mites, animal danders and various other inhalants in situations where the offending allergen cannot be avoided. Prior to initiation of therapy, the clinical sensitivity should be established by careful evaluation of the patient’s history confirmed by diagnostic skin testing. Allergy shots should not be prescribed for sensitivities to allergens that can easily be avoided. Although allergy shots have been proven to be highly effective in treating the underlying cause of allergies, patients on allergy shots may experience side effects. Numerous controlled studies have demonstrated the clinical efficacy of immunotherapy with cat, dust mites, and some pollen extracts. Nevertheless, responses are variable, and in a few studies patients reported no appreciable benefits. As with all allergenic extracts, severe systemic reactions may occur. In certain individuals, these life-threatening reactions may be fatal. Your Allergy Specialist can provide you with all allergy treatment options and full prescribing information. Your Allergies and Asthma
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