1. science
2. medicine

VC
VCDIALOGUE
DIALOGUESESSION
SESSION
13 April 2015
13 April 2015
Main Lecture Hall, Academy of Islamic Studies
Main Lecture Hall,
Academy of Islamic Studies
• Former Vice Chancellor, Tan Sri Dr. Ghauth Jasmon
initiated High Impact Research (HIR) programme in
2010 with an internal grant of RM10 million per year
• In 2011, Cabinet decided to provide RM590 million to
UM to support HIR with the mandate of making it into
the Top 100 world ranked universities by 2015 based
on QS Ranking
• Targeting 3,400 Tier 1 ISI/WoS publications by 2015
MISSION
To promote multidisciplinary
research and research
collaboration with local and
overseas universities which can
result in publications in high
impact journals.
VISION
To conduct world-class research in
niche areas and elevate the
international reputation and world
university ranking of the university.
Establish international
linkage with ivy-league
universities and conduct
collaborative research with
academic icons, including
Nobel Laureates
OBJECTIVE
Forge linkages with
successful Malaysian
scientists overseas
To accomplish its
vision and mission,
HIR will strive to :
Attract top notch
postgraduate students
to do research and
help meet national
needs
Target publications
in top Tier 1 ISI/WoS
journals, including
Nature and Science
Set up a Central Core
Facility housing cutting
edge equipment for use by
UM as well as other local
universities
Identify new and
advancing research
fronts and implement
new technologies into
research
Work with industry
partners to train young
scientists in enhancing
research skills
CYCLE 1
CYCLE 2
CYCLE 3
TOTAL
No of
Projects
Budget (RM)
No of
Projects
Budget (RM)
No of
Projects
Budget (RM)
No of
Projects
Budget (RM)
Medicine
17
72,919,330
5
18,677,800
21
15,856,404
43
107,453,534
Engineering
23
52,715,469
25
63,208,120
11
12,635,648
59
128,559,237
Science
10
57,534,645
-
-
15
23,495,488
25
81,030,133
Dentistry
8
13,194,753
13
15,092,351
3
5,410,531
24
33,697,635
Comp. Science
4
3,141,090
6
3,201,200
4
1,196,200
14
7,538,490
Chancellory
9
104,451,948
2
6,289,250
3
76,778,254
14
187,519,452
Arts, Social
Science
-
-
-
-
6
10,718,650
6
10,718,650
71
303,957,235
51
106,468,721
63
146,091,175
185
590,156,460
FIELD
TOTAL
NO
KEY PERFORMANCE INDICATORS (KPI)
TARGETS
1
TIER-1 ISI/WOS PUBLICATIONS
3,400
2
BRIGHT SPARKS
746
3
ACADEMIC ICONS
183
4
PATENTS
515
•
•
•
•
By June 2016, we must fulfill our promised KPI to KPM
Failure to do so will make UM lose credibility
May affect our request for HIR II
Life without HIR II will be unthinkable
 Lose everything we have built up under HIR I
 Our networking with ivy league universities and academic
icons
 Our talent pool of young researchers
 Our dream of being a top world-class university
WE CANNOT AFFORD TO FAIL!
KPI
ACHIEVEMENT
(2011-2015)
TARGET
(2011–2016)
PERCENTAGE
(%)
Tier-1
2096
3,400
61.64 %
Bright Sparks
339
785
43.18 %
Academic Icon
182
199
91.45 %
Patent
155
539
28.75 %
As of 31 March 2015
TIER 1 PUBLICATION (2011 – 2015)
January
February
March
Achievement
1
Medicine
21
52
89
136
8
9
8
25
323
2
Engineering
20
112
240
414
29
38
20
87
873
3
Science
11
61
108
177
8
8
6
22
379
4
Dentistry
0
4
9
34
1
2
0
3
50
5
Computer Science & IT
0
6
12
70
5
1
1
7
95
6
Chancellory
18
108
64
139
12
7
7
26
355
7
Arts. Social Science &
Humanities
0
0
5
14
1
0
1
2
21
TOTAL :
70
343
527
984
64
65
43
172
2,096
ON
Achievement
2015
Achievement
2014
Achievement
2013
Achievement
2011 2012
FACULTY
TOTAL
As of 31 March 2015
NO
FACULTY/KPI’S
BRIGHT SPARKS
ACADEMIC ICON
PATENT
1
Medicine
56
22
39
2
Engineering
104
60
45
3
Science
84
44
27
4
Dentistry
8
7
0
5 Computer Science & IT
17
6
6
6
Chancellory
69
42
36
7
Arts, Social Science
and Humanities
1
1
2
339
182
155
TOTAL :
As of 31 March 2015
HIR EXPENDITURE AS AT 31 MAC 2015
72.5
HIR
expenditure
72.5 %
As of 31 March 2015
Source : UM Library
HIR Publications
1500
1000
500
Others Publications
267
403
481
984
0
2013
2014
HIR
published
2013
2014
78.7% from
HIR Publications Contribution
481 (54.5 %)
984 (78.7 %)
Others Publications
403 (45.5 %)
267 (21.3 %)
UM Total Q1
Publications
in 2014
884
1,251
UM TOTAL PUBLICATIONs
Source : UM Library
As of February 2015
NO
FACULTY
NO OF STAFF
INVOLVED IN HIR
NO OF STAFF IN
FACULTY
PERCENTAGE OF
STAFF INVOLVED
1
Medicine
176
555
31.7 %
2
Engineering
97
179
54.2 %
3
Science
160
281
56.9 %
4
Dentistry
64
90
71.1 %
5
Comp. Scie & IT
33
77
42.9 %
6
Chancellory
41
-
7
Arts, Social Sciences &
Humanities
75
-
8
Others
-
1,675
646
2,857
TOTAL
Academic Staff in UM involved in HIR
As of 31 March 2015
22.6 %%
22.6
UM Ten Year Overall Ranking
UM ISI-indexed
publications
Highest in Malaysia
@ 3,142 in 2014
USM
UPM
UKM
UTM
Source : UM Library
NUS
UM ISI-indexed
publications
based on Selected
Asean Universities
NTU
UM
Uni. Chulalongkorn / Uni. Mahidol
Uni. Indonesia
Source : UM Library
LIST OF PUBLICATION IN TOP JOUNALS
NO
NO OF PUBLICATIONS IN JOURNAL
IMPACT
FACTOR
1
6 in Nature Genetics
29.648
2
2 in Nature Communications
10.742
3
1 in Nature Medicine
28.054
4
2 in Lancet
39.207
5
2 in PNAS
9.809
6
19 in Nature Scientific Report
5.078
7
1 in Chemical Society Reviews
45.661
8
1 in IEEE Transactions on Industrial Electronics
6.5
9
1 in IEEE Transactions on Industrial Informatics
8.785
10
2 in Journal of Pathology
7.33
11
1 in IEEE Communications Surveys and Tutorials
6.49
Updated on 5th April 2015
April 2015
Another
14 months
June 2016
TIER-1 Publications
Need to step up publications, targeting 85 Tier 1
papers per month
 Only papers which are in print or with evidence of
acceptance considered for KPI
 Evidence of submission will not be counted
 Since it takes up to 6 months to get a submitted
paper processed and accepted, it is advised that
all papers should be submitted by December 2015
UM & HIR Bright Sparks
• To increase the number of Bright Sparks, all PIs and co-PIs
must submit the names of those who qualify to HIR
Secretariat
• Even PIs and Co-PIs who did not target for BS in the original
proposal should do so to help UM
• HIR BSP need to have CPGA of 3 and above AND
two ISI publications (Tier 1 and Tier 2)
• Publication of Tier 1 ISI papers subsequent to appointment
entitles them to RM200 per paper from the PI’s grant
Academic & HIR Icons
 This is one KPI which we should be able to reach 100%
 We only need another 19 icons, and hopefully, this can
be done by June 2015 (the next KPM Audit)
 PIs & Co-PIs should check the CVs of their new
collaborators and if they meet the criteria, submit the
names to HIR Secretariat
Patents & Copyright
We have only achieved 28.75 % of this KPI
Require another 384 patents, copyrights, etc
PIs and Co-PIs are encouraged to file their
patents, etc. through UMCIC
TOTAL
3,844
1,200
1,818
Post-Graduate Student (Local) :
1,031
Post-Graduate Student (International) :
1,988
HIR PHASE 2 (HIR II)
• Indications are good that we will get HIR II (2016-2020)
• Met up with KSU II, MoE, who has openly supported UM
to go for it
• Met with EPU Minister who asked us to do the paper
work for RMK 11 funding
• DPM gave positive vibes in his speech during the HIR
Book Launch
• PM has given assurance that government will support
HIR II provided we try to get into the top 100 QS World
University Rankings by 2016!
• Assuming that HIR II will have a budget of RM1 billion,
with OPEX RM600 million and CAPEX of RM400 million
INTRODUCTION TO HIR II
• RM500 million of OPEX for fundamental research,
RM100 million of OPEX for applied research
• Using the formula of RM100k per Tier-1/Tier 2*paper,
we need 5,000 papers between 2016-2020
• Projects that fit into National Blue Ocean Strategy
(commercialization) started in HIR I will be supported
• Balance between fundamental and applied research
• Good to develop HIR II from HIR I
• Fundamental research
will remain the
INTRODUCTION
TOcornerstone
HIR II of HIR
II as envisaged under the MEB (HE) to be continued to
raise the bar
• Flagship projects that target top 10% of discipline will be
given special attention - (UM Nobel Research Path)
• Fundamental research must have strong impact to society
• Towards patent, product and commercialization
FORMING A RU CONSORTIUM
Incentive to Promote Publications
in Top Journals
• All publications in the top 10% of each discipline will be equivalent
to 2 Tier 1 papers.
• In addition, the number of equivalent papers according to the
journal impact factors are as listed in the table below:
Journal Impact Factor (IF)
No. of equivalent papers
<5
1
>5 - <10
2
>10 - <15
3
>15 - <20
4
>20 - <25
5
>25 - <30
6
>30
15
• TOUCHING LIVES
• IMPACTING SOCIETY
• COMMERCIALIZATION
(NBOS)
Vickneswaran
Mathanneswaran
Developed 3D physical models using
computer programming
3D Printing Technology helps better
training of neurosurgeons
CBMTI Sdn Bhd
Turn over 2014
Profits 2014
RM 300 000
RM 130 000
Hany Ariffin
Research in Leukemia.
Survival rate of children
with acute lymphoblastic
leukemia improved from
56% to 81%
Noor Azuan Abu Osman
Developed custom made prosthetic
legs for disabled people equipped
with fibre-optic sensors.
Nur Aishah/Yip Cheng Har/Teo Soo Hwang/
Looi Lai Meng
Breast cancer study leads to better prognosis
and treatment outcome of the 3 major
ethnic groups. Clinical trials utilizing new
agents and techniques will benefit women
with breast cancer in Malaysia.
5-year observed survival rate from
58.4% to 75.7%
Tunku Kamarul Zaman
Stem cell research will lead to significant
contribution in upscaling to clinical trials in treating
cartilage and tendon associated diseases
(Tissue Engineering & Regenerative Medicine)
As the result of HIR, two spin off products will be launched pending
approval from UM.
1. OrthoRegen which utilises progenitor and stromal cells to repair and
enhance injured tendons.
2. ChondroRegen, which is a spin-off product that provides mesenchymal
stem cell-based therapy that regenerates articular cartilage defects.
Expected to hasten the recovery rate in patients following injury, reduced
medical care and socioeconomic burden; and may even enhance patients'
performance.
Faisal Rafiq Mahamd Adikan
Flat Fibre study leads to Flat fibre manufacturing
facility creating waves and orders for custommade advanced fibres.
The installation of optical sensors in structures such as
bridges offer value added features such as maintenance
free and intelligent buildings and thus realizing green
buildings and structures.
Flexilicate Sdn BhD (to be formed soon)
Expected to generate RM300k+ in two years.
Harith Ahmad
Photonics research leads to collaboration
with Telekoms Malaysia. Initiates and
develops fabrication of the planar light wave
circuit device and the fibre-tothe- home
(FttH) technology for high-speed broadband.
CREATIVITY INDEX
NO
IMPACT
QUANTITY
VALUE
EXPECTED
IMPACT TIME
TOTAL
1
Generating Income
100
200,000
5
100,000,000
2
Saving from High Impact
Research
80
250,000
5
100,000,000
3
Human Capital
Development (Student)
800
1,700
5
6,800,000
4
Commercialization of
Patents produced by HIR
20
100,000,000
3
6,000,000,000
5
Reduce cost to send
students oversea to
pursue study
800
550,000
5
2,200,000,000
TOTAL
8,406,800,000
CREATIVITY INDEX
NO
ITEMS
TOTAL
1
Overall Total Impact
8,406,800,000
2
Cost of Operating Expenditure (OPEX)
600,000,000
3
Cost of Capital Expenditure (CAPEX)
400,000,000
4
Creativity Index
8.41
Creativity Index = Overall Total Impact
OPEX + CAPEX
=
8,406,800,000
1,000,000,000
=
8.41
1.
2.
3.
4.
5.
Active Ageing
World Without Conflict
Eco-Resilient Cities
Sustainable Resources & Technology
Pushing Economic Borders
Faculty of Medicine
Fac. of Engineering
1. Material & Nanotechnology
2. Environment and Biosystem
3. Electronics & Power System
4. Sustainable Energy System
Faculty of Science
1. Bioinspired Innovative Material Discovery & Design,
2. Molecular Biology, Biochemistry & Biotech,
3. Earth, Ocean & Athmosphere Interaction,
4. Agricultural, Plant & Animal Scicene
5. Frontiers of Science & Multidisciplinary
Studies
Faculty of Computer Science and IT
1. Safety and Security 2. Educational Equity
3. Cloud Services
4. Digital Communities
5. E-Commerce
Chancellory Projects
1. Fruit Crops
2. Bacteria Methylome
3. Medicinal Plants 4. Genomics. Protomics using NGS,
5. Water Resources for Aquaculture
1. Infectious Disease &Immunity,
2. Cancer & Drug Discovery,
3. Public Health & NonCommunicable
Disease
4. Ageing & Regenerative
Medicine
EXAMPLE
FROM HIR I
1. Cancer Project –
Breast, Ovarian, leukemia
2. Crop Improvement (Banana)
3. Obesity, Diabetes and HIV
4. OMICS Projects
5. Flat Fiber
6. Mobile Cloud Computing
7. Advanced Engineering and Material
Processing
8. Elderly Research – MELor
PRIORITY PROJECTS FOR HIR II
1.
2.
3.
4.
5.
6.
7.
8.
9.
Those involving UM Nobel Fellows and UM Advisory Council Members
Projects that have an impact to society (health, lifestyle)
Those that have an economic impact through commercialization
Projects that involve ivy league universities and institutions
o (Harvard, Cambridge, Caltech, RIKEN, Oxford, MIT)
Projects that involve international consortium with excellent track
records
Projects headed by UM Distinguished Scientists
o (Merdeka Awardees, Mahathir Science Awards, Toray S&T
Awardees)
Continuation of HIR I projects that have exceeded their KPIs and received
topping up grants
Projects that have the potential to serve as stepping stones to the Nobel
Prize
-OMICS projects that can be serviced by HIR Business Unit and will result
in top Tier 1 publications
SPECIFIC NICHE AREAS
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
Crop improvement (banana and other NKEA projects)
Lifestyle and Wellness Projects :
 obesity, diabetes, nutrition, HIV/AIDS
Cancer projects :
 breast, ovarian, cervical, NPC, leukemias,
- OMICS projects :
 genomics, proteomics, transcriptomics,
 metabolomics, methylomics, pharmacogenomics
Ionic liquids
Flat fibre & Sensors
Graphene
Laser, optics, and photonics
Quantum physics
Drug discovery
Mobile cloud computing
Nanomaterials
Prosthetics and clinical biomechanics
Advanced engineering and material processing
RETURN OF INVESTMENT (ROI)
BASED ON APPLIED RESEARCH
1.
Laser LED System
 Prof. Datin Saadah bt Abdul Rahman
 Phillips, Osram, Hitachi and international markets
2. Waste water and waste solid management
 Prof. Agamuthu A/L Pariatamby
 IWK, DOE, local councils and industries worldwide
3. Intelligent street light and traffic systems
 Dr. Chong Wen Tong
 Local councils (Putrajaya) and road concessionaires worldwide
4. Artificial Intelligence CCTV, including face recognition
 Dr. Chan Chee Seng
 Police, Immigration, banks, security system providers
Ready for corporate listing. Each worth over RM1 billion
(Vincent Wong, KPM Adviser (Commercialization) & CEO, MY InnoHub
OTHER RESEARCH PRODUCTS ALMOST
READY FOR COMMERCIALIZATION
1. Ultrasonic Palm Oil Separator
2. Robotic Oil Palm Harvester
3. Plasma Sterilizer
4. Neutron Scanner
5. Bio Compost Enhanced Nano NPK Fertilizer
Information obtained from Mr. Vincent Wong, PMO
Innovative Applied Research
• Under HIR II, RM100 million will be provided for
innovative applied research projects which will be
considered as falling under the National Blue Ocean
Strategy.
• These projects will have a different set of KPIs with
the emphasis on copyrights, intellectual properties,
skilled manpower training, patents and
commercialization.
• Continuanity of HIR I
• Value of HIR I to continue with Commercialization
NOBEL FELLOW
DISTINGUISHED
FELLOW
UM Nobel Fellow
Dr. Barry Marshall
(Nobel Prize in
Physiology or
Medicine, 2005)
Professor of Clinical
Microbiology at the
University of
Western Australia
UM Nobel Fellow
Dr. Ryoji Noyori
(Nobel Prize in
Chemistry, 2001)
RIKEN Institute and
Professor at Nagoya
University
UM Distinguished
Fellow Dr. Rita Colwell
Distinguished University
Professor at the
University of Maryland
at College Park and at
Johns Hopkins
University Bloomberg
School of Public Health
UM Nobel Fellow
Dr. David Baltimore
(Nobel Prize in
Physiology or
Medicine, 1975)
Robert A. Milikan
Professor of Biology
at the California
Institute of
Technology
UM Nobel Fellow
Sir Dr. Richard J
Roberts
(Nobel Prize in
Physiology or
Medicine, 1993)
British Molecular
Biologist in New
England Biolabs,
USA
UM Distinguished
Fellow Dr. Wong
Chi-Huey
President of
Academia Sinica,
Taiwan and Chief
Science Advisor of
the Ministry of
Science, Taiwan
Paper Publications with HIR Advisory Council
NO
TITLE
PI
JOURNAL
ADVISORY
COUNCIL
1
EHMT1 Protein Binds to Nuclear
Factor-kappaB p50 and Represses
Gene Expression.
Dr. Ea Chee
Kwee
Journal of
Biological
Chemistry
(IF = 4.6)
Dr. David
Baltimore
2
HLA-A SNPs and amino acid variants
are associated with nasopharyngeal
carcinoma in Malaysian Chinese.
Dr. Ng Ching
Ching
International
Journal of
Cancer
(IF = 5.007)
Dr. Ryoji
Noyori
3
Comparative genomic analysis of
Helicobacter pylori from Malaysia
identifies three distinct lineages
suggestive of differential evolution
Prof. Dr. Jamuna Nucleic Acids
Vadivelu /
Research
Dr. Loke Mun Fai
(IF = 8.8)
Dr. Barry J.
Marshall
“ My team at the Marshall Centre-Helicobacter Research Lab of the
University of Western Australia has found the collaboration with the
UM HIR I extremely useful. Your University has had the foresight to
employ highly skilled Malaysian graduates and provide them with the
facilities required for producing High Impact Research. Clearly, the
emphasis towards genomics has already started to pay off. Coupled
with the unique human and other biological resources of Malaysia,
your team has a lot to offer the world as we charge into the 21st
Century, which I see as the biological century ”
Barry Marshall
2005 Nobel Laureate in
Physiology or Medicine
54
“ I fully support the University of Malaya’s
continuation of high impact research (HIR) into its
second phase. In the first phase, UM researchers
published over 1,400 papers in Tier 1 ISI/Web of
Science journals, an excellent record. It is essential
that it (HIR) be allowed to continue beyond the
five-year span of the first phase funding. I am
hopeful that the government will continue to
support this invaluable undertaking with second
phase funding ”
Noyori Ryoji
2001 Nobel Laureate in Chemistry & President
of RIKEN Institute
55
David Baltimore
1975 Nobel Laureate in Physiology or
Medicine &
President Emeritus, California Institute of
Technology
“ Having come so far in your first phase
of development, it is important that
you maintain the momentum.
Becoming a world-class research
enterprise requires consistent support
and careful nurturing. You have the
opportunity to become world-class by
finding the right people and giving
them the resources they need to
succeed. I know that you have found
impressive talent and will find more. I
hope that your government will
provide the resources to catapult you
forward ”
56
“ I have been extremely pleased with our collaboration in analyzing PacBio data
to study bacterial methylomes. This is a very exciting area of research and one
that I believe is going to lead to some major new discoveries about bacterial
epigenetics.
It has been a pleasure to visit and see first-hand the high quality of work that is
taking place at the University of Malaya. I am very much looking forward to
further collaborations with your group, to producing some joint high quality
publications.
I strongly support renewal of this program under HIR II and I particularly laud
your intentions to purchase one or more additional PacBio machines to further
the capabilities of the University. This should offer additional opportunities for
collaborations especially given the high-quality of the researchers in the
University of Malaya who are taking advantage of this capability.
I would give my very highest support to you and your colleagues and wish you
every success in your bid for HIR II, which if successful, should be extremely
beneficial to science at your University and within Malaysia ”
Richard Roberts
1993 Nobel Laureate in Physiology or Medicine
& Chief Scientific Officer, New England Biolabs
57