education Supporting Training Initiatives the otc treatment clinic Common conditions and their treatment options This module has been endorsed with the NPA’s Training Seal as suitable for use by medicines counter assistants as part of their ongoing learning. Complete the questions at the end to include in your self-development portfolio module 194 Welcome to TM’s OTC Treatment Clinic series. This handy, four-page section is specially designed so that you can detach it from the magazine and keep it for future reference. Each month, TM covers a different OTC treatment area to help you keep up-to-date with the latest product developments. In this issue, we focus on itchy skin. At the end of the module there are multiple choice questions for you to complete, so your progress can be monitored by your pharmacist. You can find out more in the Counter Intelligence Plus training guide. The last six topics we have covered are: l Hair loss (alopecia) l Heartburn and indigestion l Ovulation and pregnancy testing l Dry skin – part 1 l Nasal health and hygiene l Coughs You can download previous modules from www.tm-modules.co.uk Itchy skin author: Jane Feely, PhD for this module OBJECTIVES: After studying this module, assistants will: • Be aware of the structure of human skin and the various functions it performs • Know that itching is a common symptom of many different skin-related conditions • Be familiar with the common causes of itching, including dry skin, allergic conditions, infections and insect bites • Be able to advise on appropriate over-the-counter skin products • Be able to suggest tips to help customers look after their skin and reduce itching. An itch is such a common experience that it’s not something we usually pay much attention to – you’ll probably scratch a slight itch as you read this OTC Treatment Clinic. But occasionally that itch can become more noticeable and, rarely, more serious. This month we’re taking a closer look at the skin and what makes us itch, from common conditions like allergies to infections like ringworm and chickenpox. We’ll also look at some of the OTC products available and pass along tips that can help ensure skin stays healthy and itch-free. A closer look at skin Did you know that your skin is the largest organ in your body? According to the British Association of Dermatologists, the average adult has two square metres of skin, accounting for about 16 per cent of their weight. On average, each half-inch square of skin contains 10 hairs, five sebaceous glands, 100 sweat glands and a metre of tiny blood vessels. As you may remember from our previous OTC Treatment Clinic on dry skin, the skin is made up of two main layers – the epidermis and the dermis. The epidermis is comprised mostly of skin cells called keratinocytes. These are formed in the lowest layer of the epidermis and as they mature, they move up towards the surface of the skin. Once there, they are eventually worn off and lost, only to be replaced by new cells following behind. On average, it takes about 60 days for newly formed skin cells to reach the surface and be shed. The dermis layer is thicker than the epidermis and contains many different types of structures to keep the skin healthy. These include blood vessels that bring nutrients to the cells, nerves that provide our sense of touch, and proteins such as collagen and elastin that give skin its strength and flexibility. TM JUNE 2013 PULL OUT AND KEEP the otc treatment clinic reflective exercise Alan Smith is a regular customer at the pharmacy. He is in his early 30s and has suffered from eczema for many years. He usually obtains hydrocortisone cream on a repeat prescription from his GP, but says he would prefer to buy his supplies from you to save him and his GP time. He shows you the eczema on his hands, which is cracked and weeping. What would you recommend? Refer Alan to the pharmacist as the eczema on his hands appears to be infected. The pharmacist will likely refer Alan to his GP. A topical corticosteroid cream, for example, should not be used on infected skin. Later that day, Alan returns with a prescription for flucloxacillin and betamethasone ointment 1%. You give Alan his completed prescription. What other advice could you give? Reassure Alan that the infection should clear up within a week to 10 days. You could also consider asking Alan about his use of emollients. Which ones has he used and how helpful have they been? Does he use a bath oil? Does he apply emollient to his skin following a bath or shower? What Hair follicles also have their base in the dermis, although the hair shaft itself extends through to the skin’s surface. Each hair follicle has a small sebaceous gland that produces an oily substance to coat the hair. The dermis is also where we find sweat glands – ducts which also lead out onto the surface of the skin. Our skin performs a number of functions: l A protective barrier – healthy, well-hydrated skin is an excellent barrier against harmful agents like chemicals and bacteria. By making the brown pigment melanin, skin also helps protect against the sun’s harmful UV rays l Temperature regulation – when we’re warm, the body produces sweat and when this evaporates from the surface of the skin, it cools us down. On the other hand, when we’re cold, tiny muscles raise the hairs up off the skin’s surface, trapping a layer of warm air next to the skin l Vitamin production – when the skin is exposed to sunlight, it makes vitamin D, which is important for the growth and maintenance of bones and for healthy nervous and immune systems. PULL OUT AND KEEP TM JUNE 2013 does he use to cleanse his skin? It is important that standard soaps and bath products are avoided. Emollient preparations should be used as often as needed to keep the skin moist and hydrated. Several and frequent applications may be needed each day to achieve this. What if: Alan comes to the pharmacy saying that he is planning a walking holiday in Scotland. He reacts badly to midge bites and wants to buy a cream to treat any skin reactions to bites he suffers while he’s away. What would you recommend? Alan could use a topical corticosteroid cream (e.g. hydrocortisone or clobetasone butyrate). A combination product (i.e. a corticosteroid with an anti-itch ingredient) could be useful. Another possibility would be a topical antihistamine (but for no longer than three days’ use due to the possibility of increased skin irritation). Local anaesthetic preparations containing, for example, lidocaine or benzocaine can also help to relieve the pain of an insect bite by numbing the area. Alan should also ensure that he uses insect repellent and covers as much of his skin as possible (e.g. with long sleeves, long trousers, long socks and possibly a hat). What is an itch? The correct medical name for itching is pruritus. Put simply, an itch is any kind of tingling or irritating sensation in the skin that causes us to scratch the affected area. Itching may occur all over the body (generalised) or in one specific area (localised). Scratching is a reflex action to an itch, but unfortunately, the more a person scratches, the more they itch. This is termed the ‘itch-scratch cycle’ and breaking it can be an important part of treating an itchy skin condition. Skin that is scratched frequently is at greater risk of bacterial infection, permanent scarring, thickening or even changes in colour. Itching is often triggered by the release of the chemical histamine – something you will be familiar with from modules on hayfever and allergies. This is also why itching is a common symptom of allergic conditions. Ask questions There are many different causes of itching, ranging from a simple reaction to an insect bite to a more serious systemic condition such as an overactive thyroid gland. Sometimes it is obvious what the cause is – a visible rash is a good clue. At other times, the cause won’t be immediately apparent and you may have to ask questions. This will help you to determine if your customer can self-treat or if they should be referred. Questions that can help you include: l How long has the itching been present? Did it come on suddenly or gradually? Is it there all the time or does it come and go? Has this itch occurred before? l Where is the itch? Location is a key factor. For example, itchy eyes and nose are indicative of hayfever; an itchy scalp may suggest headlice; vaginal itching is a symptom of thrush; anal itching can be linked to threadworms or haemorrhoids, etc l Is there a rash? If so, what does it look like? Does it appear to be spreading? l Is anyone else affected? Chickenpox and scabies are contagious, for example, and if the cat has fleas or a friend has headlice, it might provide valuable clues l Does anything make it worse? Is it linked to cosmetics, jewellery or washing powder? Is it connected to a particular event (e.g. a recent course of medicine, something unusual in the diet, use of cleaning chemicals, etc)? Common causes of itch l Dry skin Skin that loses moisture feels tight and prickly, so it’s no surprise that dry skin is one of the most common causes of itching. Some people have naturally drier skin, while for others, dry skin is a feature of ageing. Dry skin can also occur if a person doesn’t drink enough water, if they are exposed to drying chemicals such as harsh soaps or solvents, or if the air where they live or work is low in humidity. l Allergic conditions a) Atopic eczema This is the most common form of eczema and is primarily seen in children. According to figures from the National Eczema Society (NES), between five and 15 per cent of UK children are affected by atopic eczema by the age of seven. Many grow out of it though – in approximately 74 per cent of children, the eczema will have disappeared by the age of 16. The exact cause of atopic eczema isn’t clear, but research suggests that a combination of genetic and environmental factors play a part. Symptoms include dry, itchy, scaly skin, typically affecting the insides of the elbows, backs of the knees and the face. When the eczema flares up, open, weeping or crusted sores may develop as a result of scratching or a secondary bacterial infection. Flare-ups may be triggered by pollen, soaps, detergents, house dust mites and animal hair. the otc treatment clinic fleas, ticks and bedbugs. Symptoms may vary depending on the type of insect, how often the person was bitten and how sensitive they are to the bites in question. For some, it may be merely a couple of small, itchy, red bumps that fade within a short period of time. For others, it can be numerous Itchy skin can be a nuisance as well as a sign that something is wrong red, inflamed areas with blisters or even b) Contact dermatitis a secondary bacterial infection. This type of eczema occurs as a result of Flea bites tend to be grouped in lines or contact with irritants or allergens in the clusters, often below the knees and commonly environment. The NES states that nine per around the ankles. Bedbug bites, which are cent of the UK population is affected by this becoming more of a problem in hotels condition, which is the most common type of worldwide, often occur on the face, neck, work-related skin disease. hands and arms. Symptoms of contact dermatitis may range Ticks often stay attached to the skin for from mild dryness and skin redness to the some time while they feed. They should be appearance of skin burns with red, painful, removed carefully to make sure that the fluid-filled skin ulcers. Soaps, detergents, mouthparts don’t remain in the skin and chemicals, hair cosmetics, bleach and raw food become infected. Ticks may also carry bacteria are common triggers. that cause Lyme disease – an infection with symptoms such as a rash and high fever. c) Urticaria A repellent spray should be recommended Urticaria, also known as hives or nettle rash, is to customers who know they will be visiting a raised, itchy rash that may be limited to one places where insect bites are a possibility. part of the body or spread across larger areas. l Infections Urticaria affects around one person in six at some point in their lives. It is most common in a) Chickenpox children, women aged 30-60 and people with This is an infection caused by the varicella zoster a history of allergies. virus. Most children seem to catch chickenpox This condition occurs when a trigger at some time – usually before the age of 10. It causes high levels of histamine and other causes a rash of red, itchy spots that turn into chemicals to be released in the skin. Exactly fluid-filled blisters before forming scabs that what prompts this release may not be clear, eventually drop off. Some children have only but exposure to materials like latex and certain a few spots, while others seem to be covered. foods or drugs may be a factor. Symptoms may The spots often appear first on the face, also be triggered by non-allergic sources like ears and scalp and then under the arms, on the rubbing the skin, cold, heat, sunlight or chest, stomach, arms and legs. A fever may also physical exercise. In many people, the cause be present. A child with chickenpox will be remains unknown. infectious from one to two days before the rash The rash of urticaria may develop quickly appears until after all the blisters have crusted and then disappear within a few hours or days. over (usually five to six days after the start of If it clears completely within six weeks, it is the rash). called acute urticaria. Chronic, long-term Paracetamol can be recommended to help urticaria is much less common and may reduce a fever, along with soothing lotions like continue over many years. calamine to address the itchy rash. l Insect bites When certain insects bite, they inject saliva into the skin and this can trigger a reaction that leads to itchy, red lumps. In the UK, common culprits include midges, mosquitoes, b) Tinea Tinea is a fungus that thrives in human skin. There are different types, but the most common are tinea pedis, which causes athlete’s foot, tinea corporis (ringworm) and tinea cruris (dhobie itch or jock itch). Athlete’s foot, as its name suggests, affects the skin between the toes. The skin is itchy and may appear red or white, cracked and peeling or inflamed and weeping. The infection is contagious and is often acquired by walking barefoot in changing rooms at swimming pools or gyms. This infection usually responds well to OTC antifungal products. Ringworm starts with a small area of infection on the skin and then spreads outward, with the centre of the rash healing as it goes. This gives the infection its typical ring-like appearance. The rash can range from being mildly irritating to very itchy and inflamed. Dhobie itch affects the skin around the groin area and upper thigh. It is most common in young people and in more obese individuals and often occurs with athlete’s foot. c) Scabies This is a contagious skin condition caused by a tiny mite that burrows into the skin. The main symptom is intense itching. Scabies can be spread by prolonged skin-to-skin contact or by self care tips l If itching is severe, apply an anti-itch cream or lotion to the affected area l Avoid scratching whenever possible l Cover any itchy area that you can’t avoid scratching l Keep fingernails short, smooth and clean to prevent scratching l At night, wear cotton gloves or socks to prevent scratching l Protect skin from the sun l Do not wear tight, occlusive clothing. Choose smooth-textured cotton or silk rather than synthetic fabrics. Remember that wool can be itchy l Choose mild soaps and rinse any soap off your body l Take comfortably cool (not hot) baths and showers l Use non-soap cleansers followed by a liberal use of emollient l Apply cool, wet compresses. This can help protect the skin and prevent scratching l Use a mild, unscented laundry product when washing clothes, towels and bedding. Using the extra rinse cycle in the washing machine may be helpful l Avoid substances that irritate the skin or cause an allergic reaction. These can include nickel, jewellery, perfume, cleaning products and cosmetics. TM JUNE 2013 PULL OUT AND KEEP the otc treatment clinic sexual contact with an infected individual. The infection may also be passed on by sharing clothes, towels or bedding with an infected person, but this is much less likely. Specific antiparasitic products need to be recommended for scabies infections (e.g. Lyclear Dermal Cream). When to refer to the pharmacist In most cases, itching will resolve once the underlying cause has been addressed. However, there are occasions when customers should be referred to the pharmacist: l Itching that persists for longer than two weeks or symptoms that keep returning l Itching so severe that it prevents the sufferer from carrying out their daily routine or interferes with sleep l Itching that appears to affect the whole body l Sudden itching or rash where there is also swelling and/or shortness of breath – this could be a sign of a severe allergic reaction l Itching accompanied by other symptoms such as fever, abdominal pain, vomiting, tiredness, weight loss, yellowing of skin or eyes, changes in bowel habits or urinary frequency l Itchy rash with inflammation, crusting or oozing – this may be a sign of a secondary bacterial infection l Pregnant women or anyone being treated for an underlying medical condition – e.g. kidney, liver or thyroid disease, diabetes l Symptoms that cannot easily be explained or don’t improve with self-care measures. OTC treatment choices There are many different products available over the counter. It can help to group these active ingredients by their mode of action. l Emollients A mainstay in the relief of dry skin and eczema, ‘emollients’ is a term used to describe moisturising products that restore the skin’s water content, preventing scaling and cracking. The regular use of emollients will help reduce itching due to dry skin and help manage eczema flare-ups. Complete emollient therapy may involve the use of different moisturising preparations throughout the day and bath additives and soap substitutes for cleansing. OTC examples include Dermol, Doublebase, E45, Diprobase, Epaderm and Oilatum. l Antipruritics As the name suggests, these ingredients are designed to help soothe pruritus (itching). Common OTC antipruritic ingredients include calamine (e.g. Care Aqueous Calamine Cream, Care Calamine Lotion), crotamiton (e.g. Eurax) and urea (e.g. Aquadrate, E45 Itch Relief Cream, Hydromol Intensive, Nutraplus Cream). Some products are also available to help cool and soothe the skin. l Topical corticosteroids Lower strength versions of some topical corticosteroids are available over the counter, while stronger products remain prescription only. These products work by reducing inflammation and are recommended for the short-term treatment of eczema and dermatitis. They can also be used to treat skin reactions caused by insect bites. Hydrocortisone, in strengths up to 1%, has been available OTC for some time. Brands include Hc45 and Lanacort. Also available OTC is clobestasone butyrate 0.05% (e.g. Eumovate) and combination products that provide a corticosteroid with an antipruritic (e.g. Eurax HC). There are a number of restrictions as to who can use OTC topical corticosteroids, how long the product can be used and for what conditions it can be sold. Talk to your pharmacist about how you should handle requests for these products. l Topical antihistamines These can be used in allergic skin conditions, including insect bite reactions. Common examples include mepyramine maleate (e.g. Anthisan) and diphenhydramine hydrochloride (e.g. Benadryl Skin Allergy Relief Cream). These products may cause skin irritation, so their use is not recommended for longer than three days. l Local anaesthetics These products are designed to help relieve the pain associated with skin conditions such as insect bites and stings by numbing the affected area. Common OTC ingredients include benzocaine (e.g. Burn-eze, Wasp-eze, Lanacane) and lidocaine (e.g. Dermidex Dermatological Cream, Emla Cream, Savlon Bites & Stings Pain Relief Gel). l Topical antifungals These products target topical fungal infections such as athlete’s foot and ringworm. OTC antifungals include a group of products called imidazoles. Examples include clotrimazole (e.g. Canesten AF, Care Clotrimazole 1%), miconazole (e.g. Daktarin) and ketoconazole (e.g. Daktarin Gold, Daktarin Intensiv). Other antifungal ingredients include terbinafine (e.g. Lamisil), tolnaftate (e.g. Scholl Athlete’s Foot) and undecenoates (e.g. Mycota). assessment questions: itchy skin For each question, select one correct answer. Discuss your answers with your pharmacist. 1. Which of the following statements is TRUE? a) The skin is the largest organ in the body b) The epidermis is thicker than the dermis c) An average adult has one square metre of skin d) Sweat glands are found in the epidermis 2. Which of the following statements is FALSE? a) The skin makes the pigment melanin b) The skin produces vitamin C c) The skin acts as a protective barrier d) When sweat evaporates from the skin, it cools the body’s temperature n n n n n n n n 3. The correct medical name for itching is: a) Urticaria b) Psoriasis c) Pruritus d) Dermatitis n n n n 4. Which of the following customers is most likely to be suffering from contact dermatitis? a) An adult who has suffered an insect bite n b) A young child with asthma who also has an itchy rash on her face n c) An adult with a red skin rash who has recently started work as a hairdresser n d) An adult with an itchy rash caused by a drug allergy n 5. Which of the following customers can selfmedicate with an OTC corticosteroid cream? a) A pregnant woman with a red, itchy rash and an under-active thyroid gland n b) An adult with crusty, itchy rash who has run out of his prescription corticosteroid cream n c) A child aged eight with a red rash on his face n d) An otherwise healthy man with an itchy rash on the back of his hand n 6. OTC clotrimazole cream would be suitable for which of these people? a) A child with chickenpox n b) An adult with ringworm n c) An adult who has been stung by a wasp n d) A teenager with a red, itchy rash between his toes n Warning: The content contained in this module is the copyright of Training Matters and cannot be reproduced without permission in the form of a valid written licence granted after July 1, 2011. Unbranded pictures copyright Photodisc/Digital Stock/iStockphoto. Published under licence by Communications International Group Ltd, 162-168 Regent Street, London W1B 5TB. Tel: 020 7434 1530. 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