Long-lasting net treatment for the control of malaria vectors Highly effective treatment for new or used mosquito nets and curtains Can withstand a minimum of 20 washes and still remain effective Water-based, low odor formulation Treatment kit available for individual use READ THE LABEL BEFORE YOU BUY: USE PESTICIDES SAFELY. ICON® 10CS contains lambda-cyhalothrin ICON® is a registered trademark of Syngenta Group Company © Syngenta 2007 Syngenta, Professional Products, Schwarzwaldallee 215, P.O. Box CH-4002 Basel, Switzerland Tel: +41 61 323 1111, Fax: +41 61 323 5608 Email: [email protected] Web: www.syngentavectorcontrol.com Important: Always read and follow label instructions before buying or using these products. Syngenta and its affiliates warrant that their products conform to the chemical description set forth on the products’ labels. NO OTHER WARRANTIES, WHETHER EXPRESS OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY AND OF FITNESS FOR A PARTICULAR PURPOSE, SHALL APPLY TO SYNGENTA PRODUCTS. Syngenta and its affiliates neither assume nor authorize any representative or other person to assume for them any obligation or liability other than such as is expressly set forth herein. UNDER NO CIRCUMSTANCES SHALL SYNGENTA AND ITS AFFILIATES BE LIABLE FOR INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THEIR PRODUCTS. No statements or recommendations contained herein are to be construed as inducements to infringe any relevant patent now or hereafter in existence. ©2005 Syngenta. Syngenta Crop Protection AG, Basel, Switzerland Long-lasting treatment for mosquito nets and curtains Knockdown of Aedes aegypti Knockdown of exposure Aedes aegypti after 3-minute to washed aftertreated 3-minute exposure to washed nets with ICON Maxx nets treated with ICON Maxx What is ICON Maxx? ICON® Maxx is the new and innovative long- This continual drive to improve the lives of those at ICON Maxx is an insecticide treatment designed to convert existing lasting treatment for mosquito nets and curtains risk of vector borne disease throughout the world has or new untreated mosquito nets into long-lasting insecticide-treated nets. offering protection against mosquitoes and led to the development of ICON Maxx, an individual It is based on the WHO-approved capsule suspension formulation of malaria. long-lasting insecticide net treatment. lambda-cyhalothrin, ICON 10CS, plus a polymer binding agent. An ICON Maxx treatment is easy to apply Insecticide-treated nets are a widely supported tool The advanced capsule suspension technology used in ICON 10CS allows and will withstand at least 20 washes whilst used in malaria prevention and vector control the controlled release of insecticide over time. The addition of the maintaining effectiveness. campaigns worldwide. They can be used either alone polymer binder helps retain the capsules on the net fiber during washing. or in combination with other key vector control This innovative combination provides protection from mosquitoes for at For many years Syngenta and its legacy companies ICI measures such as indoor residual spraying (IRS) with least 20 washes. and Zeneca Public Health have been at the forefront ICON 10CS as part of an integrated approach to of developing new and innovative solutions for disease prevention. to the introduction of products for indoor residual Sleeping under a bed net protects the user from spraying, mosquito net treatment, space spraying and mosquito bites by either repelling or killing them. Performance of ICON Maxx mosquito larviciding. This reduces the risk of malaria transmission The efficacy of ICON Maxx treated nets has been determined in indepen- and provides the user with an improved sleeping dent laboratory studies. Tunnel tests (see Figure 1) undertaken by the experience through reduced disturbance. London School of Hygiene and Tropical Medicine demonstrate that after 20 washes, nets treated with ICON Maxx still provide effective control However, many nets untreated by insecticide remain of Anopheles gambiae mosquitoes (Yates and Rowland, 2007). in the field, leaving the user at increased risk of contracting malaria. Further studies in Tanzania also demonstrate the effectiveness of ICON Maxx treated nets (see Figure 2). Anopheles gambiae were exposed to Withstands at least 20 washes Can be used to treat new or used nets Kills mosquitoes in addition to repelling further improves the safety profile of the product. ICON 10CS is in a low WHO hazard category – class 3 – unlikely to present acute hazard in normal use. them A water-based low-odor formulation Available as a convenient treatment kit containing everything required to treat The Maxx binding agent is considered to meet US EPA criteria as a low risk polymer (represents minimal or no risk to man). Label recommendations should be followed at all times. a net. 25 washes 30 washes gambiae Figure 2. exposure Mortalityto ofwashed An. gambiae following following to washed ICON Maxxexposure treated nets ICON Maxx treated nets et al, 2007). environmental safety profile. The encapsulated nature of the formulation 20 washes % blood feeding % mortality Figure 2. Mortality of An. inhibition treated nets is exceeding the WHOPES criteria of 80% mortality (Rowland ICON 10CS used in ICON Maxx has an excellent toxicological and 30 washes 30 washes 0 % mortality % mortality treatment 25 washes 25 washes 20 The results show that even after 25 washes the efficacy of ICON Maxx Safety Profile 20 washes 20 washes 100 100 Figure 1. Efficacy of nets treated 80 80 with ICON Maxx against An. gambiae 60 in Tunnel assays After 30 washes 60 After After 20 30 washes washes Unwashed 40 After 20 washes 100 Unwashed 40 20 80 20 0 600 After 30 washes % blood feeding % mortality After 20 washes inhibition % blood feeding % mortality Unwashed 40 inhibition % mortality Long-lasting effect from a single 90 90 95 Figure 1. Efficacy of nets treated Figure 1. Efficacy of netsAn. treated with ICON Maxx against gambiae with ICONassays Maxx against An. gambiae in Tunnel in Tunnel assays washed nets for three minutes and assessed for mortality after 24 hours. MAIN BENEFITS OF ICON MAXX FOR USERS 95 95 100 Knockdown of Aedes aegypti after 3-minute exposure to washed nets treated with ICON Maxx 90 The treatment of the nets is a simple and easy process that can be undertaken in the field or factory. the control of insect vectors of disease. This has led % knockdown % knockdown % knockdown Introducing ICON Maxx 100 100 100 100 80 80 60 60 40 40 100 20 20 80 0 0 60 Figure 2. Mortality of An. gambiae following exposure to washed ICON Maxx treated nets 21 washes 21 washes 25 washes 25 washes 40 An.gambiae mortality at 24 hrs after 3 minute exposure in cone test at 24 hrs after 3 minute An.gambiae mortality Line denotes efficacy criteria as set by WHOPES 20 exposure in cone test Line denotes efficacy criteria as set by WHOPES 0 21 washes 25 washes References An.gambiae mortality 24 hrs after 3 minute Yates, A and Rowland, Mat(2007) Evaluation exposure in cone test of a Long Lasting Insecticidal Net (LLIN) Treatment Line denotes efficacy criteria as set by WHOPES produced by Syngenta. Unpublished Rowland M, Mosha F, Magesa S, Lyimo I, Tungu P, Malima R, Maxwell C and Yates A (2007) Evaluation of ICON Maxx long lasting insecticide net treatment in experimental huts in Tanzania. Unpublished An ICON capsule bound to a mosquito net
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