ABL ATLASense Biotech Ltd. Excellence in Bio Monitoring Executive Summary ABL ES0114.4 About ATLASense Biotech Ltd. is a privately owned biomedical engineering spinoff company. ABL draws on the IP and decades of pioneering monitoring achievements of Atlas Engineering (www.atlas-arl.com). Our mission is to develop and produce multi-parameter, connected health Vital Signs Monitoring Systems Patch (Pat. Pend.). We envision that our flagship monitors will become a significant backbone enabler in emerging, next generation remote patient monitoring markets. Hospital Monitoring Market The Physiologic Monitoring Systems market is well-established, primarily as hospital-grade means to help evaluate a patient’s condition and make appropriate decisions. The monitors display physiological signals, including ECG, respiration, noninvasive blood pressure (NIBP) and body temperature. In-Hospital Monitoring Issues Well-known problems associated with patient monitors include: the need to shave the areas under the electrodes; prepare the skin; tape the wires to the body to minimize detaching. Remote Patient Monitoring Market Healthcare providers are now refocused on curbing 30 day readmissions and keeping patients out of hospitals by migrating to home monitoring following discharge. Remote patient monitoring (RPM), homecare telehealth, is an emerging multi-billion dollar mobile health market of real-time ambulatory healthcare. It allows patients to be monitored at home. Telemetric (wireless) hospital monitoring systems allow the patient to be moved within transmission range without being disconnected from central station monitoring by eliminating the cables linking the patient to the monitor. Key players include Philips, Spacelabs and Welch Allyn. The market size is projected to exceed $4Billion by 2018. Such monitors are expensive and often require maintenance. And, some hospitals do not have the personnel to interpret the monitored data. RPM is increasingly used with the elderly and the chronically ill. RPM allow such patients and their physicians to closely monitor changing medical conditions and intervene, if need be. This emerging market and its key players are discussed in http://ftp.jrc.es/EURdoc/JRC71141.pdf. RPM could save the health care industry $700 billion over 15 to 20 years and help hospitals avoid costly readmissions. . 1 ATLASense RPM Solution DESCRIPTION ATLASense is in advance development stages of a pioneering, disposable, low cost RPM patch, the ABL8200i. Unmatched in comprehensive monitoring performance with a tiny patch, it comprises high level integration: A sensors; signal processing; wireless communication; battery and adhesive. The ABL8200i is a derivative of market-proven Atlas Engineering workhorse platform, AR7000. FEATURES & BENEFITS  Motion tolerant shave free ECG  Cuffless relative blood pressure trending  Shared parameters sensors  Wireless BTLE transmission  End-to-end gateway  Skin pigment insensitive pulse sensor  Wire-free, low-profile, non obtrusive  Proprietary algorithms  Disposable, 2 weeks operation  Continua Health Alliance compatible  Open protocol for 3rd party applications developers* SINGLE SITE MONITORED PARAMETERS ECG; EMG; Respiration; Pressure pulse wave; Ambient and surface body temperature; Skin Conductance; Tri-axial acceleration /activity/position; Stethoscope heart/lung sounds. DERIVED PARAMETERS & ALGORITHMS ECG HR/ HRV/ Arrhythmia/Tachycardia/ Bradycardia; PTT (Relative BP enabler); Sweat; Hypothermia/Hyperthermia; Body position/Fall detection. 3rd PARTY MONITORING APPLICATIONS  Pre-surgery status home monitoring  First responders' triage  Elderly/chronically-ill home monitoring  Remote checkup  Quality of sleep and sleep disorders * Embedded software applications and integration of  Functioning of implants monitoring modules (e.g., blood pressure, glucose, weight  Consumer fitness and wellness and multi-lead ECG).  Epileptic events  Medication efficacy and VALUE PROPOSITION compliance  Having an early indication of a risk factor Neuromuscular rehabilitation cardiac, stroke, respiratory, inflammation Tracking emotions at home  Fall detection  Built-in fall detector  Hypoglycemia  Minimizing hospital readmission  Cardiac arrhythmia  Tracking medication efficacy  Apnea  Peace of mind of real-time monitoring  Pre-Eclampsia (Pregnancy The patch will cost under $10 to produce. induced hypertension) ABL SCREENING APPLICATIONS  Cardiac arrhythmias  Sleep apnea 2 NEAREST COMPETITION ABL is more comprehensive in monitoring changes in vital signs, and a low cost disposable. iHealth wearable blood pressure vest and smartphone ECG. Lifewatch multiple patch V-Patch, ECG only WHY ATLASense ATLASense starts with over 3 decades of licensor's knowhow, global achievement record and reputation, customers, IP, and FDA experience. WHY NOW The time for ABL patch is now- currently no direct competition on the market, unique value proposition for commercial success. TEAM Founded by Dan Atlas (www.atlas-arl.com), a veteran biomedical and engineering expert with engineering cofounders, backed by multidisciplinary team of advisors exceeding 300 man-years of top multidisciplinary talent: Bioengineering, business and medical expertise. CV's available under NDA. FINANCIAL DATA Available under NDA. CONTACT PERSON Dan Atlas +972.50.779.5686 mailto: [email protected] 3