Patents for Five Senses’ Organ Disorders Yuxing Liu Ph.D Academy of Oriental Medicine at Austin Allergies/Nasal Disorders • Xin Yi Wan: Magnolia flower Teapills • Cang Er Zi San Wan: Upper Chamber teapills • Bi Yan Pian: Nasal Inflammation Pill • Bi Yuan Pian: Nasal Sinusitis Pills • Pe Min Kan Wan / Bi Min Gan Wan • Yu Ping Feng jia Cang Er Zi San /“Jade Screen w/ Xanthium” Xin Yi Wan “Magnolia Pills” Ingredients Xin Yi hua; Bai zhi; Fang feng; Qiang huo; Xi xin; Gao ben; Chuan xiong; Sheng ma; Mutong; Functions Disperses wind cold, open the nasal passage; transform phlegm and dampness Biomedical Actions Diaphoretic, anti-inflammatory, analgesic Features: Postnasal drip; decrease or loss of sense of smell Sinus and maxillary pain, Nasal Congestion or copious watery or white nasal discharge Clinical Applications Wind-Cold type Acute and chronic sinus congestion, sinusitis and rhinitis; particularly good for chronic and stubborn sinus congestion with no heat signs, or with white or watery nasal discharge and postnasal drip Sinus or frontal headaches Precautions Contraindicated in sinus congestion from Heat. Packaging and Dosage Bottles of 200 pills 8 Pills Tid. Brands Plum Flower Brand; Herbal Times Brand Cang Er Zi san Wan “Xanthium Powder Pills” Ingredients Precautions Cang Er Zi; Xin Yi hua; Bai Zhi; Bo He; Baizhi can cause anxiety or palpitation in patients with heart qi deficiency Functions Disperse Wind; eliminates heat/cold; Dosage Opens the nasal passage; relieves pain. 8 pills Tid Clinical Applications • For acute and chronic sinusitis and rhinitis • Nasal congestion with profuse thick nasal discharge; sneezing, red itching eyes and frontal headache • Brands: Plum Flower Brand Bi Yan Pian / “Nasal Inflammation Pills” Ingredients Cang er zi:Xanthium + Xin yi hua: Magnolia flower+ Bai zhi:Angelica Jing jie: Schizonepeta + Fang feng: Ledebouriella+ Wu wei zi: Schisandra Zhi mu: Anemarrhena +(ye) Ju hua: Chrysanthemum. + Jie geng:Platycodon +Gan cao: Licorice Lian qiao: Forsythia; Yi tang(sugar) Functions Treats Wind-Heat (w/ pungent, cold herbs) • Expel Wind-Heat • More superficial: open nasal passages (nasal congestion, runny nose) • Decrease swelling, transforms phlegm • *Cooling formula Clinical Applications Allergies - acute or chronic rhinitis, nasal sinusitis, common cold, seasonal hay fever - Sx: runny nose w/ lrg amts of yellowish, thick discharge w/ foul smelling odor (bacterial infection) Stuffy nose Hay fever, other allergies w/ rhinitis Precautions - Cang er zi is sl. toxic, ∴, follow recommended dosage Brands, and Dosaget Chung lien Brand (Chung Lien Drug Works; Wu han) with Yi tang(sugar) Plum flower Brand (no sugar) 3-4 tablets/pian TID/ 8-12 pills/wan TID adults: 3-4 tabs, TID w/ warm water after meals Children (5-10 yrs): ½ dose Children (>10 yrs): regular dose Available brands: Jade dragon Brand: Plum flower brand -Baizhi, +Huang bai+Du huo. Bi Yuan Pian “Deep source nasal congestion tablet” “Nose Nasal Sinusitis Pills” Ingredients • Cang er zi; Xin yi hua; Qian cao gen; Jin yin hua; Ju hua; 13 additional ingredients: Jing jie, Jie geng; Huang qin, Chi shao; Di gu pi; Bai zhi. Bo he .(Huo xiang; Long dan cao) Functions Treats Wind-Heat (w/ pungent, cold herbs • Expel W-H (stickier, hotter) • Deeper: sinus pressure • Open nasal passages, relieve stuffy nose • Stop pain • clear thick phlegm-heat Clinical Applications 1) Acute or chronic rhinitis, nasal congestion; sinusitis - Sx: Runny nose w/ yellowish, thick discharge and bad odor, nasal bleeding 2) Stuffy nose or obstruction 3) Remove nasal polyps, Remove blood stasis Precautions - Cang er zi is sl. toxic, ∴, follow recommended dosage - No recommended for use w/ children Brand, and Dosage Min-Kang brand (Min-kang Drug Manufactory; Yichang) Pe Min Kan Wan / Bi Min Gan Wan Ingredients “Te xiao bi min gan wan” •Cang er zi: Xanthium; Xin yi hua: Magnolia flower; Bai zhi: Angelica root. •Huo xiang: Patchouli; Long dan cao. •Xiong dan zhi: Bear gall bladder (no longer included); Niu huang: Cattle gall stones; Ye ju hua: Wild chrysanthemum. Functions • Expel Wind, Eliminate inflammation – Clear Heat • Opens nasal passages • Resolves toxin, transforms phlegm, dispels damp • Stop headache d/t Wind • Reduce asthma d/t allergy Clinical Applications Allergies/Nasal symptoms: obstruction (heat) – in the front of the face (runny, stuffy nose), headache, dizziness===Rhinitis, acute or chronic sinusitis Modern: allergic rhinitis, chronic rhinitis & nasal sinusitis (stuffy, runny nose, sneezing, cough or asthma d/t allergy), acute/chronic bronchitis Precautions Not longer time use Brands; Dosage Fo Shan United Drug Manufactory 2-3 pills, TID; chronic cases = take for 30 d (= 1 course of tx) Available brands Plum Flower brand: Xin yi hua+Cang er zi; Huo xiang; Ye ju hua; Fang feng; Bo he; Zi su ye; Ban lan gen; E bu shi cao. Herbal Times brand: Xin yi hua +Bai zhi; Fang feng; Gao gen; Chuang xiong; Xi xin; Sheng ma; Gan cao; Bio Essence Brand: Xin yi hua+Cang er zi+Bai zhi.; Jing jie+ Fang feng+wu wei zi; Lian qiao+Jie geng+Gan cao; Ye ju hua; Yu Ping Feng jia Cang Er Zi San “Jade Screen w/ Xanthium” Ingredients Yu ping Feng Cang Er Zi san Functions Clinical Applications Wei Qi xu & acute nose sx; specially formulated for Austin area allergies Patents for Throat disorders Common symptoms Sore throat, loss of the voice; dryness feeling; Plum-pit qi; itching feeling in the throat Qing Yin Wan / “Pure Sound Pills” “Golden Throat Tablets Ingredients •Ge gen; Chuan bei mu; Tian hua fen; He Zi rou; Wu mei; Gan Cao; Honey Functions • • • Nourish yin and moisten throat Clear heat from the lung and throat; Stop pain Brand and packaging Tong Ren Tang (Beijing) 3 gram honey pills scaled in wax ball, 10 pills per box Clinical Applications 1) Hoarse or raspy voice, or loss of voice following an upper respiratory tract infection, overuse or smoking. Much used for singer, teachers and public speakers 2) Recurrent or chronic soreness and irritation of the throat 3) Dryness of the oral cavity, either from a local pathology, the after effect of radiation treatment, or systemic pathology such as diabetes. 4) Prevention or alleviation of discomfort from polyps on the vocal cords Precautions - avoid spicy or excessively greasy foods, and other obvious irritants(like ciga) while using it Methods of taking it Take half to one pill, Bid. Chew, or cut and form into smaller pieces and swallow. The large bolus(pill) also can be soaked and dissolved in hot water. Xuan Mai Gan Jie Chong ji Ingredients • Xuan Shen; Mai dong; Gan cao; Jie geng Functions Nourish yin and moisten throat Clear heat; Stop pain Brand and packaging Clinical Applications 1) Hoarse or raspy voice, or loss of voice following an upper respiratory tract infection, overuse or smoking. 2) Recurrent or chronic soreness and dry throat Precautions - avoid spicy or excessively greasy foods, and other obvious irritants(like ciga) while using it Methods of taking it 1 pack per time, Tid Jin Sang Zi Pian / “Golden Throat Tablets” Ingredients • Luo Han guo; Qing Guo; Bo He nao; Sugar Functions • • Nourish yin and moisten throat Clear heat, relieve cough Clinical Applications 1) Hoarse or dry throat 2) Chronic deficiency cough emanating from the throat Precautions - avoid spicy or excessively greasy foods, and other obvious irritants(like ciga) while using it Brand, Packaging and Dosage Guanxi Jin Sang Zi Medicine Factory; (guanxi) boxes of 20 candy tablets Suck on one candy per dose, as needed Shuang Liao Hou feng San / “Superior Sore Throat Powder” Ingredients •Huang lian; Bing Pian; gan cao; Shan dou gen/Ku Shen; •Niu Huang, Zhen zhu; Qing dai. Functions • Disperses swelling • Clear toxic heat from the throat; Stop pain Strong heat purging topical formula for severe sore throat Brand Meizhou Medicine Factory; (Guandong) Clinical Applications 1) Heat toxins of the for painful mouth sores throat: acute sore throat, laryngitis, tonsillitis. Also 2) Acute sinus or ear infection. 3) Topically in ulcerative skin lesions, burning and bleeding wound Precautions -no using during pregnancy. Borneol(Bing pian), is illegal in California; and can not use long time; only for 1-2 days. -- Do not eat greasy, oily food when taking Rx Packing and Dosage Bottles of powder in Spray form. For throat and mouth application, spray 3 times/day. For sinusitis, spray in nose 5 times/day. For toothache, sprinkle powder on cotton ball and place against the sore gum For oozing mid-ear inflammations, wash with hydrogen peroxide. Fu fang Xi Gua Shuang / “Medical Compound Watermelon Frost” Ingredients Xi gua shuang:Watermelon frost; Qing dai:indigo;Chuan bei mu: Fritallaria; Shan dou gen:Sophora; Bing pian:Borneol; She gan:Belamcanda; Bo he nao:Mint oil; Gan cao:licorice Functions • • Disperses swelling;Stop pain Clear heat, Cools Xue Heat; resolve toxic; • Stops bleeding (for open wounds) Wonderful patent for sore throat, mouth disorders. Brand Guilin Chinese Medicine Factory; (Guanxi) Clinical Applications 1) Heat toxins causing acute sore throat, laryngitis,. 2)Acute tonsillitis or painful mouth sores 3)Toothache, tooth-gum bleeding. 4) Topically in ulcerative skin lesions, burning and bleeding wound Precautions - no using during pregnancy. Borneol (Bing pian), is illegal in California; and can not use long time. Packing and Dosage Bottles of powder (3 gram) in Spray form. For sore throat; blow powder into back of throat with tube. For sinusitis, spray into nose 5 times/day. For toothache, sprinkle powder on cotton ball and place against the sore gum For ear inflammations, apply topically to external ear For bleeding wounds, apply powder directly, cover with bandage. Patents for Ear and Eyes Disorders • Er Long Zuo Zhi Wan • Er Yan Ling Oil / “Specially Effective Ear Inflammation Effective Drops Ear Oil” • Ming Mu Di Huang Wan /“Rehmannia Pills to Brightenthe Eyes” • Ming Mu Shang Qing Pian /“Brightenthe Eyes, Clear (heat from) the Upper (body) Pills” • Shi Hu Ye Guang Wan / “Dendrobrium Night Bright Pills” Er Long Zuo Zhi Wan / “Tinnitus Left Supporting Pills” Ingredients •Liu Wei Dihuang wan+ Chai hu; Wu Wei zi; Ci Shi (Magnetite) Functions • Tonifies Kidney yin and restrain exuberant yang • Improve Kidney function and fluid metabolism Brand Lanzhou Foci Pharmaceutical Factory; (Guandong) Clinical Applications 1). Kidney Yin def. with hearing problem, specially tinnitus and gradual loss of hearing acuity. 2)Mostly used for chronic tinnitus with a high pitch that is worse with fatigue, exertion and at night. 3) For Liver and kidney yin deficiency with Liver Qi stagnation-----visual problems like optic neuritis, optic nerve atrophy and central retinitis. 4) The biomedical conditions that may be alleviated by this formula include tinnitus in the elderly, chronic labyrinthitis, Meiniese syndrome and hypertension Precautions Contraindicated during early phase of acute illness(cold or flu) Carefully use on the patients with Sp def. . Packing and Dosage . Package in bottles of 200 pills. 8-12 pills Tid daily on an empty stomach. The dosage may be spread out or two lots of 12-18 pills may be taken. Er Yan Ling Oil / “Specially Effective Ear Inflammation Effective Drops Ear Oil” Ingredients • Huang lian; Huang Bai; Huang Qin; Da huang; Ku shen; Bing Pian; Oil base. Functions • Clear heat, resolve toxins Clinical Applications 1) Acute ear infection due to bacteria or viral microbes.( Externally). 2)Acute sore throat, and tonsillitis ( Orally taking) • Brand, Packaging and Dosage; China National Chemicals I./E Corp; ( Zhejiang ) Bottles of 5 cc of oil Apply 2 drops topically, Tid/ or as needed. “ Qi Ju Di Huang Wan / Lycii Chrysanthemum Pill Ingredients • Liu wei di huang wan + gou qi zi & Ju hua. Functions • • Tonify Liv & KI Benefit/brighten the eyes Brand Clinical Applications eye weakening, eye strain, discomfort, blurry vision, excess tearing and sensitivity to light Packing and Dosage bottles of 200 pills; 8 pills Tid. Best take with salt water ” Ming Mu Di Huang Wan / “Rehmannia Pills to Brightenthe Eyes” Ingredients •Liu Wei Di huang Wan+Gou Qi zi, Ju Hua=Qi Ju Di huang wan. +Dang gui; Bai shao; gan cao; Bai ji li; Gou teng. Functions • Tonify the Liver & Kidneys, • Nourish Liver blood, restrains Liver yang, • Brighten the eyes and improve vision Brand Lanzhou Foci Pharmaceutical Factory; (Gansu) Clinical Applications 1)Chronic eye disorders due to liver & KI Yin and Blood def. Weakness of vision, floaters, chronically sore dry irritated eyes, bloodshot eyes, photophobia, excessive lacrimation, night blindness; Non-acute glaucoma; optic neuritis; retinal degeneration and atrophy of the optic nerve, or degenerative visual disorders. 2) Dizziness, vertigo or hypertension from Yin def. with yang rising. Precautions - not suitable for acute inflammatory eye disorders. Caution in patients with digestive weakness and spleen def. Packing and Dosage Bottles of 200 pills. 8-12 pills Tid daily before meals. The dose maybe spread out, or two lots of 12-18 pills maybe taken, morning and evening. Ming Mu Shang Qing Pian / “Brightenthe Eyes, Clear (heat from) the Upper (body) Pills” Ingredients •Shan Zhi zi; Lian qiao; Huang lian; Huang qin; Ju hua; Bai ji li; Dan zhu ye; Mai dong; Che qian zi; Da huang; Dang gui; Calcium sulphate. Functions • • Brightens the eyes, benefits vision. Clear heat and damp heat from the Liver and Liver channel, disperse Wind Heat; Brand Tianjin Drug Manufactory; (Shandong) Clinical Applications 1). Wind heat, heat in the liver channel or liver yang rising type inflammatory eye disorders associated with infection Biomedical conditions like acute conjunctivitis, glaucoma; Ear and oral infection from Liver & gallbladder heat, Damp heat or Heart fire. 2) Acute urinary tract infection, systitis, urethritis or prostatitis from heat or damp-heat Lin Syndrome, or heart Fire invading the Small intestine. 3). Itchy inflamed skin disorders like eczema, urticaria and dermatitis. Precautions - no using during pregnancy. Packing and Dosage 4-8 pills Bid; Shi Hu Ye Guang Wan / “Dendrobrium Night Bright Pills” Ingredients Ren shen+Mai dong+Wu wei zi. Huang lian; Sheng di huang; Ju hua; Ling Yang jiao; Shui niu jiao. Niu xi; Rou cong rong; Gou Qi zi; Chuan xiong, fang feng; Zhi ke. Shi hu; Bai ji li; Qing xiang zi; Jue ming Zi. Functions • Clear heat, nourish liver & KI yin • Subdues yang, brightens the eyes. Brand Plum Flower Brand Tientsin Drug Manufactory; Tianjin Clinical Applications 1) Many Eye disorders due to Liver yin Def. With rising liver yang or heat. Symptoms include: failing vision, photophobia, poor night version; pressure in or behind the eyes, dryness or redness with irritation 2) Cataract, glaucoma, retinitis, photophobia, optic neuritis, and recovery from eye diseases or surgery. Precautions -No using during pregnancy (Niu xi). -This product lists antelope horn (Ling yang jiao)----endangered wildlife Packing and Dosage It meets Australian GMP standards. Bottles of 200 pills. Take 8 pills Tid/ day.