1. health and fitness
2. aging

29/08/2011
How to Treat Cancer
(Otto Warburg, 1944 Nobel Prize-Winner)
An effective approach to treating cancer MUST include:
• Detoxification (heavy metals, chemicals, etc.)
• Boosting the Immune System (anti-oxidants)
• Regeneration of damaged tissues (organic nutrients)
• Destruction of cancer without destroying the body
• Psychological Healing
Mercury and Free Radicals having power to induce
diseases
What is a Free Radicals & Radicals ?
Free radicals : Any species molecules/atom as Gas•
with unpaired electron, very reactive,
having rate const. > 108 M- 1 sec- 1
Non Metals Gas • : • H; • OH; • NO; NO2•; HO2• ; • OONO
Metal Gas • : Hg • + (rad ion mercuro), Hg- metal (amalgam)
Radicals
: Compound with unpaired electron, very
reactive, not stable, solid a liquid phase.
Biradical
: Radical-radical intermolecular interaction
depends on the distance of the unpaired
electrons between the radical compounds
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The Source of Radicals and Free Radicals


Air pollutants (metal particles, mining industry, vechicles, cancer electropoluted)
UV light : < 290 nm pass through the hole of ozone layer which permit the migration
of free radicals/ radioactive to the earth.
Radiotherapy : using g – ray , X – ray, etc
Mechanism :
.OH, H . , e -
H2O
. OH + Ar
Concept accepted :
.
.
Ar OH
.
Ar OH + Ar OH
(very reactive)
(Short live)
Contradictery Biradical (Kosower) :
HO- Ar --- Ar-OH
(Covalen, Stable)
.
.
Ar OH + Ar OH
.
HO - Ar
Hg Characteristics
Relativistic effects
Mercury, with 6s25d10 are particular important for the very fast s2 electron , resulted
relativistic effect of mercury ion radical Hg.+* , which are not stable and still in exited
state. Since the monomer Hg.+* radical ion is not stable, the unusual +1 oxidation
state entirely due to the stability of dimmer.
80Hg200 (liquid)----hv---> 80Hg* 200 (vapour) ------UVC---->- e - + 80Hg.+
Sensitizer, electronically exited molecule created upon strong photon absorption,
process bimolecular interaction. It is more likely to occur with a long lived electronically
excited energy donor, by transfer energy to other substrate. Sensitizer material absorbed
energy UV well and fast , keeping the energy as long as they wanted and then transfer to
other substrate . Many sensitizer to decompose or undergo transformation as the
reaction mixture undergo irradiation.
80Hg200 (liquid)-----hv----> 80Hg200* (gas *)
Two phases liquid and gas* co-exist at room temperature,
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Varied X – Aromatic + Hg in Tridest Solution interact with
Light ( sun of Nov, Des, Jan )
Procedure : X Aromatic ( 5x 10-3 M in tridest water ) + 1 g.Hg / dental Amalgam to absorb Hg
 Put the baker glass outside to be sun-shining for 7 days (cover by aluminium foil)
 Isolated the X – Aromatic sun shining product
 Dried and analyzed by ESR, IR, and HPLC.
 Evidence of the mechanism Sensitizer & “ Relativistic effect “

Balur is Detoxification,
means that Free Radicals are pulled out of the Body and
neutralized
Principles:
a. The mercury and its amalgamated can dilute in proteins/amino acids/NH2 (amide)
b. The Free Radicals are electrostatic (+)
Application Concept
a. Oral treatment of amino acids to absorb metal radicals and make it “float”
b. The radicals are pulled out after attracted and floated by scavengers and other
compounds rubbed over the whole body skin.
c. The rubbing process done with the body laying on the grounded copper plate in
order to neutralized the exerted radicals
Indicators of the treatment procedure
Neutralized radicals will stick and polymerized on the copper plate forming unique
architecture figures.
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BALUR
Humanity already posseses the fundamental scientific technical
and industrial know how to solve the problem
“Balur” is an experimental skin rubbing of
human body with scavengers in water solution
while laying on grounded copper table.
It is a unique tool with which an active object, together with
the scientific skilled observer, able to formulate many
different and specific hypotheses.
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BALUR
• It might together as a team enclosure basic
physics science as virtual object becoming
real/ visual subject
• Balur resulted human knowledge belongin to
the universe
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Mechanism reaction of free radicals with Aromatic Amino Acid,
Nucleic Acid ( DNA ), Uric Acid, and Lipid 1
The Gas ● (free radicals and gas Hg ●+ ) react to amino acid aromatic
(AAA) Produce aggregate in ligand or chelation.
5-9* The Tertiary Structure of Globular Proteins
Allows them to bind other molecules
( nearly spherical shape)
Selectively and Transiently
*Biochemistry : Moran Scrimgeour
Biradical
Biradical : Self assosiation radical-radical without covalen
bonding R•R• ----- R•R• (Edward M. Kosower: “An
Introduction to Physical Organic Chemistry”)
G. Zahar (Desertation 1993 )
Biradical product of Gamma Irradiated X – Aromatic in tridest solution
Figure :
H
C - C - C OOH
H
.
.
+ OH
H
OH
C - C - C OOH
NH2
.
H
H - COOH - C - C
H
H
OH
NH 2
.
H
H
OH
OH
H
.
H
NH 2
C - C - COOH
Found: The chelation of OH to nucleo aromatic, able to release again
when the power is more 2 tons ( Infared Kbr disk - 8 ton )
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Biradikal Spectrum
(ESR (Electron Spin Resonance)
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Tembaga
Laying on the copper (Cu) plate
Grounded
GROUNDING
Penggunaan larutan acetosal sebagai scavenger OH, sambil
melepas
Hg/amalgam yang terikat di protein, DNA, RNA dsb.
Larutan acetosal dalam air sebagai scavenger radikal.
Acetosal + (OH•) --------> (Ac•OH Ac•OH )n k =
Ac etosal + OH
Protein
o
o
n Ac OH
Ac OH
o
Ac OH n Hg* (uap)
o
(Hg )* + e
HO -Phenya la nin
o
HO - Phe
di tangkap Cl
HO - Phe
H= 1650 G
Kemungkinan structure ini yang disebutkan sebagai Bi-Tyrosin yang flourensensi.
Saran : Pisahkan gumpalan diPlasma dan ESR dst.
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Empat atom Oksigen pada acetosal mampu merenggangkan/melepas Hg
dalam ikatan ligand dengan DNA atau protein sel tubuh
Protein……….Amalgam
Amalgam
ligand
The Gas• (free radicals and Gas Hg•+) react with aromatic amino
acid (AAA) produced aggregation in ligand or chelation
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Specific changes to individual amino acids
Method for amino acids
Reaction/ detection
Commens
Tryptophan
1.Lost of fluorescence
Fluorescence changes: excitation
280nm, emission 342 nm
Lost of the native fluorescence of
tryptophan
2. Formation of
tryptophan oxidation
products
Fluorescence: (acid) excitation
360 emission 450nm; (alkaline)
excitation 327nm emission
342nm; HPLC
Product of such N-formyl
kynurenine are fluorescent
oxidation nproducts (Amino acids
3, 184, (1992))
Tyrosine
Bityrosine: Fluorescence
excitation 315nm, emission
420nm; HPLC separation with
Fluorescence, or ECD detection,
GC-ms.
Hydroxylation product L-DOPA
can be measured by HPLC
(DOPA present naturally in some
proteins)
Bi tyrosine are highly fluorescent
but interference problem can
occur in biological matrices
(Methods. Enzymol. 233, 363,
1994; Punchard, NAand Kelly, FJ
eds, (1996) Free Radicals: a
Practical Approach, p.171. IRL
Press, Oxford)
Methionine
Oxidation to methionine
sulphoxide and sulphones (HPLC
or GC-MS)
specific enzyme repairs
methionine sulphoxide residues
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1. Amalgam ( Hg metal ) ligand
Cu Hg Se Hg
Zu Hg As Hg
Mn Hg Pb Hg
Co Hg Cr Hg
Cd Hg Ca Hg
e- +
H2O → e -αq
e-αq
e-+ O2 → O2• -
Hg •+
Hg •+
Hg Cu
e -αq
+protein
Hg •+
Cn
•+
Hg
+protein
+protein
Hg •+
•
CnHg O2
•
CnHg
•
CnHg
•
CnHg
O2 • -
Cn
•+
Hg
O2 • 17
2. Mercury-Seng
e- + H2O → e -αq
Hg •+
e-+ O2 → O2• -
ee -αq
Hg• + • + e αq
Hg
Hg• + Hg Zn e αq
Hg Zn
e αq
Hg Zn
Hg Zn
D2• Hg •+
O• Hg •+
O2 • -
Hg •+
Hg •+
O2 • -
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2. Mercury -Krom
e- +
H2O → e -αq
e-+ O2
•→ O2
Hg Cr
Hg •+
Hg •+
O2 • -
e-αq
Hg •+
Hg •+
e-αq
Hg •+
Hg •+
O2 • -
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Ikatan Hidrogen
Symetric
C
Hg •­
Hg•­
e
Biradikal
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The G-quartet Structure
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1
2
3
Hg
1.
2.
3.
Hidrogen N˙O Agn
Assosiated / Biradikal → ( HD – Phe ) n →Biradikal
Hg – in Biradikal structure
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Geometric possibility
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The Balur Process
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Material keluar melalui kulit?
Partikel diambil dari kulit, diamati dengan
mikroskop Fluoresen
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1.2
1
Electrical current from copper plate to
the ground during balur treatments
0.8
0.6
B1
0.4
B3
B5
0.2
0
Variable Cu concentration
100
90
80
70
60
50
40
30
20
10
0
b1 Cu
b3 Cu
b5 Cu
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Observasi Limbah Balur
(Observation of rubbing waste)
Unique architecture of waste crystal on copper plate
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Frozen Rubbing waste formed Shell
Florescence
microscopic image
Polarized light
microscopic image
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Confocal laser images
Tube confirmed
hyperlink1
Confocal laser images
Tube confirmed
hyperlink2
Confocal Laser 200X
Confocal Laser 400X
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Frozen waste containing huge number mercury
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Themodynamic Point of View
• Principle that systems tend toward states of
maximum entropy (systems with zero energy exchange across their
boundaries)
• Systems held at constant temperature do not
tend toward their states of maximum entropy.
They tend toward their states of minimum
free energy (normal human physiology)
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Closed Chains are more stable at lower
temperature
Open Chains are more stable at higher
temperature
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29/08/2011
F = Free Energy
More Free energy of Energetic compound
F Open Chains
F closed chains
ΔS
-ε
T0 = temperature collaps
Temperature
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Hasil SDS PAGE Limbah Balur
Iwan
Sutiman
Marker
90 kD
10 kD
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29/08/2011
Uji injeksi limbah balur terhadap 23 ekor mencit bertumor telah
memperpanjang masa hidup, semua mencit perlakuan masih hidup sampai
saat ini, sementara 10 ekor mencit bertumor tidak disuntik limbah telah mati
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