Solid State Medical Imaging:
X-Ray and Endoscopy
SAMPLE
The Medical Image Sensors market is expected to double over the next five years. M&A
are increasing. Discover how Medical Imaging is being reshaped!
Overview of the technical & economic requirements for Medical Imaging applications
October 2014
Le Quartz - 75 cours Emile Zola - 69100 LYON-Villeurbanne
Tel: +33 472 83 01 80 - Fax: +33 472 83 01 83
Web: www.yole.fr
Table of content
1)
2)
3)
4)
Executive Summary ………………...........................p.4
Introduction, Definitions & Methodology …….…p.16
What’s Happened in the Last Two Years?...........p.39
Medical Image Sensor technologies overview….p.13
–
–
–
–
–
5)
CCD image sensors
CMOS image sensors
Amorphous silicon flat panels
Technologies comparison
Specificity of X-ray imaging
6)
Market segmentation ....................................p.64
–
–
7)
Market drivers by segment
Technology positioning
Product categories description .....................p.72
–
Focus on endoscopy applications
o
o
Medical Image Sensors Market Overview ...…….p.35
–
Global imaging market
o
–
Endoscopy market
o
o
–
Forecasts in revenue /volume split by product category
Forecasts in revenue and in volume split by product
category
a-Si flat panel sensors market
o
© 2014 •
o
CMOS medical image sensors market
o
–
Split by technology (CCD, CMOS and a-Si)
Forecasts in revenue/volume/wafer shipments
CCD medical image sensors market
o
–
o
Split by technology (CCD & CMOS)
Forecasts in revenue/volume/wafer shipments
X-ray imaging market
o
o
–
Forecasts in revenue/volume
2
-
Forecasts in revenue and in volume split by product
category
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Rigid endoscopes

Market revenue/volume

Market drivers

Players

Technologies
Flexible endoscopes

Market revenue/volume

Market drivers

Players

Technologies
Camera pills

Market revenue/volume

Market drivers

Players

Technologies
Disposable endoscopes

Market revenue/volume

Market drivers

Players

Technologies
Table of content
–
Focus on X-ray imaging
o
o
Dental X-ray imaging Market revenue/volume

Market drivers

Players

Technologies
Medical X-ray imaging Market revenue/volume

Market drivers

Players

Technologies
10) Medical Image Sensors Challenges….p.287
11) Summary and Conclusions………………p.299
8) Medical Image Sensors Supply Chain Analysis..p.267
–
–
–
–
–
–
Rigid endoscopes
Flexible endoscopes
Camera pills
Disposable endoscopes
X-ray intraoral detectors
X-ray flat panel detectors
9) Medical Image Sensors Value Chain Analysis...p.279
–
–
–
–
–
–
–
© 2014 •
Disposable endoscope value chain
Flexible endoscope value chain
Rigid endoscope value chain
CMOS camera pill value chain
A Si flat static panel detector value chain
A Si flat dynamic panel detector value chain
CMOS panel intra oral detector value chain
3
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Some Companies Cited in the Report
AGFA, Alcon, Austria Microsystems, CMOSIS (Awaiba), BioVision Technologies
LLC , Caeleste, CapsoVision Inc., Carestream Health, Circon, Cyber Medical,
Dongbu Hitek, e2v, EndoOptiks, Escalon, FiberTech, Fujifilm, Fujinon, General
Electrics, GI View, Giotto, Given Imaging, GMM, Hamamatsu, Hitachi, Hologic,
Hoya Life Sciences, Imix, IntroMedic, Intuitive Surgical ,Invendo Medical, ISDI,
Italray, Jinshan Group, Karl Storz, Konica Minolta, Medigus, Micro-Imaging
Solutions, Olympus, ON semiconductor (Cypress), OSAT, VT & Aptina, Palodex,
Panasonic, Perkin Elmer (Dexela), Philips, Primax, Pyxalis, RF Systems labs,
Richard Wolf, Samsung, Shimadzu, Siemens, Sony, STMicro, Stryker, Swissray,
Teledyne DALSA, Toshiba, TowerJazz, Trixell, True sense imaging, TSMC, Varian,
Vatech Human ray, Villa, VIM’S, X-Fab, Ziehm Imaging…
© 2014 •
4
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Medical Image Sensors
Scope of the report
Indirect Imaging / Software
Dependant
Direct Imaging / Hardware Dependant
Standalone
Application
Microscopy
Camera
pills
Disposable
MRI
X-Ray imagers
for intra-oral
imaging
X-Ray imagers
for 3D & large
X-Ray imagers area imaging
for 2D extraoral imaging
Microscopes
Optical Imaging
•
•
•
X-Ray based methods
Ultrasound Nuclear
Imaging Medicine
Disposable
endoscopes
Flexible
Rigid
endoscopes endoscopes
Re-usable
Integrated into a
large system
Endoscopy
Doppler
ultrasound
CT
MRI
syste
m
PET Scan
X-ray Imaging
This report will focus exclusively on direct Imaging applications.
Microscopy is excluded from that report because is hardly ever used in vivo, primarily it is used in vitro.
Indirect imaging applications will not be developed in this report as their evolution rather relies on software
processing optimization.
© 2014 •
5
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Image Sensor Technologies by Market
The table below links applicative markets and Medical Image Sensor (MIS) technologies:
Endoscopy
Application
Camera pills
market
CCD MIS
CMOS MIS
X
X
Disposable endoscopes
market
X
Flexible endoscopes
market
X
X
Rigid endoscopes
market
X
X
X-Ray Imaging
Application
intra-oral imaging
market
© 2014 •
6
A-Si MIS
X
X-ray 3D CBCT extra-oral
imaging
X
2D extra-oral
market
X
3D & large area
market
X
X
X
X
X
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Value Chain Analysis
Technology penetration per markets and market shares are provided.
© 2014 •
7
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Market Forecast for equipment / sensors
In value / volume / wafers shipments
Instruments Markets…
Sensors Markets…
…splited by Medical Image Sensors technologies
© 2014 •
8
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Value Chain Analysis
Detailed Value Chains have been added
© 2014 •
9
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Detailed Supply Chain
Updated supply chain
are available for each
product category
© 2014 •
10
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Supply Chain evolution is described
Our analysis on the supply chain evolution and the potential next targets are presented
© 2014 •
11
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Technology Trends
X-Ray Imaging Technologies Overview
•
1.
CCD Image
Intensified
Camera
2.
3.
+•
-•
X-Ray
Three main components :
Scintillator to convert x-ray into visible
light
Fiber Optic Taper for mignification
CCD sensor for light to electron
conversion
Scintillator
Fiber Optic Taper
High resolution
Buky, low field of view
CCD sensor
ADC
•
Two components:
1.
Scintillator to convert x-ray into visible
light
2. a-Si matrix array: passive pixels
(photodiodes convert light into electrons +
one TFT switch per pixel)
a-Si FPD
+•
-•
•
Very large panel, simple, economical
Low resolution, image lag, slow
Two components:
1.
CMOS FPD
© 2014 •
12
Scintillator for x-ray to visible light
conversion
2. CMOS image sensor: active pixel
(photodiodes convert light into electrons +
several transistors per pixel convert charges
to voltage, on-pixel ADC & amplifier)
•+ High speed/resolution
•- Limited size  needs sensor tiling,
expensive
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.
Processing
X-Ray
Scintillator
a-Si array
X-Ray
Scintillator
CMOS image
sensor
About The Author
Benjamin ROUSSEL
He is leading the MedTech activity (microfluidic and medical technologies)
at Yole Développement. He holds a pharmacy diploma from the University
Claude Bernard Lyon, complemented by a master degree in Technology
and Innovation Management from EM Lyon Business School.
Contact: [email protected]
© 2014 •
13
Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.