SAINT LUKE’S RESEARch ANNUAL REpoRT 2013

SAINT LUKE’S
Research
Annual Report
2013
Central Office of
Research Administration
Contents
2
A Message from Julie L. Quirin
3
Research Benefits Saint Luke’s Patients
4
Central Office of Research Administration (CORA)
6
Saint Luke’s Mid America Heart Institute
11
Saint Luke’s Cancer Institute
12
Saint Luke’s Marion Bloch Neuroscience Institute
14
Diagnostic and Interventional Radiology
15
Henry & Marion Bloch Liver Disease Management
& Transplant Center
16Nursing
17Pharmacy
18Anesthesiology
19
Women & Children
19
Spiritual Wellness
20
Saint Luke’s Hospital Institutional Review Board
21
2013 Research Day
22
2013 Research Day Winners
25
2013 Scholarly Activities
30
2013 Publications
42
2013 Abstracts & Presentations
2013 Research Annual Repor t // Central Office of Research Administration
1
A Recognized Research Leader
For more than 130 years, research and innovation have been fundamental to the
mission of Saint Luke’s Hospital and Saint Luke’s Health System. In fact, many
of our research activities, especially in cardiovascular disease and neurology, have
earned national and international acclaim.
But our commitment to research extends into many additional disciplines
throughout our organization. Nearly 350 active investigators were involved in
434 active studies in 2013.
The quality and quantity of this research demonstrates why many of the nation’s
leading clinicians choose to be part of the Saint Luke’s team. This report
summarizes their impressive work for 2013.
One of the ways Saint Luke’s supports the work of our researchers is through
the Central Office of Research Administration (CORA). CORA facilitates
investigator-initiated and sponsored trials. CORA also provides assistance in
the proper conduct of research and research compliance, helping to ensure the
research conducted at Saint Luke’s Health System always meets the highest
standards. CORA’s support is vital to the success of our research efforts.
Julie L. Quirin
Chief Executive Officer
Saint Luke’s Hospital
Saint Luke’s is dedicated to always providing the highest quality, most advanced
care possible. As you will see on the following pages, our commitment to new
technology and therapy through clinical and translational research ensures we
always fulfill this commitment.
Sincerely,
2
John Yeast, M.D.
Vice President, Medical Education & Research
Veronica Koontz
CORA Research Services Coordinator
Ellen McDowell
CORA Program Director
Mike Coffman
CV Research, Director of Operations
Lynn Parsons
CORA Compliance Manager
Julie Weiss
SLCI Research Services/Compliance Manager
Mindy Peters
CORA Clinical Research Nurse II
Dena McDonell
CV Research, Grants and Contracts Manager
Matthew Jones
CORA Research Financial Auditor
Marilyn Horn
IRB Administrator
2013 Research Annual Repor t // Central Office of Research Administration
Research Benefits
Saint Luke’s Patients
Saint Luke’s Health System is among the top research facilities in the Midwest
Saint Luke’s researchers are conducting more
than 430 research studies with nearly 350
active researchers. They have enrolled nearly
6,000 patients in research trials. And they draw
sponsorship from the National Institutes of Health,
the American Heart Association, the National
Cancer Institute, pharmaceutical and medical device
companies, as well as Saint Luke’s Foundation.
All of this makes Saint Luke’s Health System among
the top health care research facilities in the Midwest in
terms of the number and scope of studies—and a great
place to conduct clinical and translational research.
Research support
Saint Luke’s supports its medical researchers:
•S
aint Luke’s Foundation supports 13 clinical
scholars.
• The Central Office of Research
Administration (CORA) exists to nurture and
facilitate investigator-initiated and sponsored trials.
•C
ORA provides comprehensive oversight for
the Saint Luke’s research enterprise and is
the foundation for growth of research within Saint
Luke’s Health System.
•C
ORA is responsible for centralizing,
standardizing, and organizing research
practices common to all product line research
programs throughout the health system,
guaranteeing clinical and financial compliance.
Research sets us apart
Saint Luke’s research:
• Provides patients access to leading-edge,
innovative treatment options
• Showcases national and international
successes of Saint Luke’s innovations in health
care, health care policy, and outcomes
• Develops strategic collaborations among health
care providers/hospital with national, international,
and community research partners
• Attracts the highest quality providers and
supports their academic interests
• Translates best evidence into best practices of
care
• Differentiates Saint Luke’s organizations from
other regional health care facilities and contributes
to profitability of the health system
2013 Research Across
Saint Luke’s Health System
$7,557,433
external funding from federal
and private sponsors
338 active investigators
434 active studies
5,995 patients enrolled in 2013
206 publications
332 abstracts/presentations
65 studies for which CORA
mentored investigators
2013 Research Annual Repor t // Central Office of Research Administration
3
Central Office of Research
Administration (CORA)
Strengthening the Saint Luke’s Research Enterprise
The Central Office of Research Administration
(CORA) provides comprehensive oversight for the
Saint Luke’s research enterprise and is the foundation
for growth of research throughout Saint Luke’s
Health System.
Through the centralization of research
administrative services, CORA focuses on three
core responsibilities:
Services
• Centralization, standardization, and organization of
research practices common to all product line research
programs throughout Saint Luke’s Health System
• Research administration strategic plan development
and implementation
• Centralized voice of research administration for
dissemination of information, fielding research process
questions, and relationship building with internal and
external entities
Compliance assurance
• Authority to ensure clinical and financial compliance with all federal and state regulations governing the conduct and financial management of clinical research
John Yeast, M.D.
Vice President, Medical
Education and Research
Saint Luke’s Hospital
4
• Compliance, which helps to assure safety for Saint Luke’s Health System organizations and patients
• Performing financial and clinical audits
•G
overnment grants management and assistance
with industry-sponsored grants negotiation and
management
Quality practices and growth
of the research enterprise
• Incubation and mentorship of new researchers plus new product line research programs
• Research contract and budget negotiation to ensure
uniformity, and subsequent central archiving of
documents
• Relationship building with industry leaders enabling
enhanced recruitment of studies
• Training of principal investigators and research staff
Growth initiatives for the research enterprise at
Saint Luke’s Hospital, and throughout Saint Luke’s
Health System, are guided by the CORA team, which
collectively possesses nearly five decades of experience.
Saint Luke’s research teams are well positioned to
succeed thanks to resources provided by the Central
Office of Research Administration.
The research enterprise at Saint Luke’s is well
developed and growing. Research strategies within
therapeutic product lines continue to be strengthened
each year.
CORA provides the foundation of support for these
research programs as well as for seasoned investigators
and established research efforts.We are fortunate to
have the CORA staff with their expertise in research
and regulatory compliance to guide us and to add to
our success as an organization.
2013 Research Annual Repor t // Central Office of Research Administration
Saint Luke’s
Research:
Enhancing
Patient
Care
Research at Saint Luke’s Health System
spans multiple disciplines but always focuses
on providing new options for patients at
Saint Luke’s and around the world.
2013 Research Annual Repor t // Central Office of Research Administration
5
Saint Luke’s Mid America
Heart Institute
Pioneering work continues in developing treatments to improve the survivability
and quality-of-life of patients suffering from heart disease
Cardiovascular research continues to be a major
focus at Saint Luke’s Hospital. The program
currently encompasses research
programs in each of the
major clinical areas including
interventional cardiology,
cardiac surgery, heart failure
and cardiac transplantation,
cardiac electrophysiology,
echocardiography, nuclear
cardiology, and preventive
cardiology/lipid and diabetes
management.
David Cohen, M.D., M.Sc.
Director of Cardiovascular
Research
Saint Luke’s Mid America
Heart Institute
The University of Missouri
Endowed Chair in
Cardiovascular Clinical
Research at the Mid
America Heart Institute
These programs, which enroll
hundreds of patients annually
in a broad range of randomized
trials and registry-based research
studies, are essential to the
mission of Saint Luke’s Mid
America Heart Institute (MAHI). Research allows
MAHI to remain on the leading edge of cardiovascular
care. In addition to these clinical research programs,
many MAHI
cardiologists
Saint Luke’s Mid America
participate in
Heart Institute research:
research through the
Ben D. McCallister
179 active studies
Clinical Scholars
1,277 patients enrolled
Program, which
provides funding
150 publications
and support for
investigator-initiated
226 abstracts/presentations
studies.
The cardiovascular
research program encompasses centers of excellence
and core laboratories in cardiovascular outcomes
research, health economics and technology assessment,
intravascular imaging, and noninvasive imaging.
These centers of excellence currently serve as core
laboratories for a wide range of studies that often
involve collaboration with leading cardiovascular
centers and researchers from around the world.
6
2013 Highlights
An Unprecedented ‘Triple Play’
Three highly prestigious journals in one week
The three most important general medical journals in
the world are the New England Journal of Medicine, the
Journal of the American Medical Association (JAMA),
and The Lancet. Although most researchers would be
thrilled to publish a paper in one of these major journals
during their careers, in 2013, the cardiovascular
research program at MAHI was fortunate to have
three papers published during a single week – one
in each of these highly prestigious journals. Paul
Chan, M.D.,* directed a study investigating long-term
outcomes among patients who survive an episode of
in-hospital cardiac arrest that was published in the New
England Journal of Medicine. Adnan Chhatriwalla,
M.D., and Steven Marso, M.D., conducted a
study of more than 1 million patients undergoing
percutaneous coronary revascularization that explored
the contribution of post-procedural bleeding to
subsequent in-hospital mortality that was published in
JAMA. And concurrently, Randall Thompson, M.D.,
directed an important study exploring the origins of
atherosclerosis in early humans based on findings from
CT scans of mummies collected from around the globe,
the results of which were published in The Lancet. The
simultaneous publication of these three studies, each
led by MAHI investigators is testimony to the
breadth, depth, and worldwide recognition of the
quality of the science being led by our talented
investigators.
MAHI Receives Highly Competitive PCORI
Grants
MAHI investigators were honored to receive a
number of grants to support a broad range of new
research efforts in 2013. Two of these grants were
awarded to the Cardiovascular Outcomes Research
Group and its investigators by the Patient-Centered
Outcomes Research Institute (PCORI)—a
federally funded program designed to help people
make informed health care decisions, and to
improve health care delivery and outcomes, by
producing and promoting high integrity, evidencebased information that comes from research guided
2013 Research Annual Repor t // Central Office of Research Administration
* Refer to page 59
by patients, caregivers, and the broader health care
community.
One PCORI grant, PORTRAIT, is being codirected by Kim Smolderen, Ph.D., and John
Spertus, M.D., and will investigate trajectories of
clinical and patient-reported outcomes among
individuals with peripheral artery disease. The
second PCORI-funded project is being co-directed
by Dr. Chhatriwalla and Dr. Spertus and will
investigate the ability of a nurse-led educational
intervention to allow patients to make more
informed and patient-centered decisions around
percutaneous coronary revascularization. Each of
these grants was for approximately $1.5 million and
will support a range of interconnected projects over a
three-year period.
In addition to the PCORI grants, Aaron Grantham,
M.D., was awarded a $3.5 million grant by Boston
Scientific to develop and lead a multicenter
registry of patients undergoing percutaneous
coronary intervention of chronically occluded
vessels. This study, known as OPEN-CTO, will
involve many other investigators at MAHI and will seek
to improve our understanding of the short- and longterm clinical, quality of life, and economic outcomes
of some of the newest technical advances in the
performance of this highly specialized procedure.
Selected MAHI Research Programs
Cardiovascular and Thoracic Surgical Research
Under the direction of Keith Allen, M.D., and
colleagues, the Department of Cardiovascular and
Thoracic Surgery continues
to maintain an active portfolio
of research with participation
in nine FDA clinical trials
during 2013. Dr. Allen led
a number of research
studies in preventing wound
complications and enhancing
sternotomy healing following
cardiac surgery. One study
involving more than 7,000
Keith Allen, M.D.
cardiac surgical patients
published in JAMA evaluated
the effect of an investigational vaccine for preventing
Staphylococcus aureus infections in patients undergoing
elective cardiac surgery. Within this theme, Dr. Allen
is serving as national principal investigator for a
multicenter trial evaluating the safety and efficacy
of rigid sternal fixation versus wire cerclage during
sternotomy closure.
Research involving the surgical treatment of heart failure
with cardiac transplantation or mechanical circulatory
support continues to grow under the leadership of
Michael Borkon, M.D., chairman of the Department
of Cardiovascular and Thoracic Surgery and director of
cardiac transplantation, and Sanjeev Aggarwal, M.D.,
director of mechanical and circulatory support.
Dr. Aggarwal was leading enroller in the United
States in Sunshine Heart’s C-Pulse trial, which
successfully evaluated a novel extravascular counter
pulsation device placed minimally invasively around
the ascending aorta to treat patients with class III/
IV heart failure. Further studies of this device
are planned for the coming years and, if successful,
should pave the way for this novel treatment to expand
treatment options for patients with advanced heart
failure who do not require full circulatory support.
Interventional Cardiology
In addition to participating in multicenter clinical trials,
interventional cardiologists at MAHI continue to lead
a number of investigator-initiated research studies.
David Safley, M.D., has been active in studying
the evolving technique of transradial percutaneous
coronary intervention (PCI). During the past year,
along with colleagues from MAHI and several other
programs, he led a study to examine the costs of
transradial PCI as compared with transfemoral
procedures, the results of which were published in
the American Heart Journal. Another area of research
interest for Dr. Safley is quality of life in patients with
peripheral arterial disease. Along with colleagues
from the MAHI Health Economics and Technology
Assessment Group, he led a study to evaluate health
outcomes of more than 200 patients undergoing
superficial femoral artery (SFA) stenting as part of
the industry-sponsored STROLL trial. These results,
which were recently presented as a late-breaking
clinical trial at the Vascular Interventional Advances
(VIVA) meeting, were the first to demonstrate that
the early benefits of SFA stenting are largely
maintained over at least three years of follow-up.
Dmitri Baklanov, M.D., is a MAHI interventional
cardiologist and clinical scholar who is one of the
leading experts in the technique of transradial
catheterization and PCI. In addition to leading a
number of courses on this technique, Dr. Baklanov
continues to publish extensively on clinical and
economic outcomes of transradial PCI. In a
landmark study published in the Journal of the
American College of Cardiology (JACC), Dr. Baklanov
and colleagues found that although transradial PCI
is utilized in only a minority of patients undergoing
primary PCI for STEMI, its use is associated with
substantial reductions in both bleeding as well as
mortality. In addition, using data from the National
Cardiovascular Data Registry (NCDR), he found that
the combination of transradial PCI and bivalirudin
anticoagulation result in the lowest bleeding
2013 Research Annual Repor t // Central Office of Research Administration
7
outcomes across the full spectrum of patient risk.
The results of this study were published in Circulation:
Cardiovascular Interventions.
Adnan Chhatriwalla, M.D., is another MAHI
interventional cardiologist with a growing research
portfolio, focused primarily on
the application of evidencebased practice in the cardiac
catheterization laboratory.
In 2013, Dr. Chhatriwalla
and colleagues published two
important studies evaluating
bleeding complications
following percutaneous
coronary intervention (PCI).
In a study published in the
Adnan Chhatriwalla, M.D.
Journal of the American Medical
Association (JAMA), he found
that 12.1 percent of in-hospital deaths following PCI
in the United States can be attributed to bleeding
complications, and that non-access site bleeding
impacts mortality more substantially than
access-site bleeding. In a second study published
in the Journal of the American College of Cardiology
(JACC), they reported that the use of individualized
bleeding risk estimates for patients undergoing PCI
at Saint Luke’s Mid America Heart Institute was
associated with increased use of bivalirudin in
high-risk patients and a dramatic reduction
in the incidence of bleeding complications.
Finally, as described on p. 6, Dr. Chhatriwalla and
Dr. Spertus recently received a three-year research
award from the Patient-Centered Outcomes Research
Institute (PCORI) to create and test a decision aid to
educate patients about drug-eluting and bare-metal
8
stents and support shared decision-making with respect
to stent selection at the time of PCI.
Cardiovascular Outcomes Research
Under the joint direction of John Spertus, M.D.,
M.P.H., and Carole Decker, R.N., Ph.D., FAHA,
CPHQ, the MAHI Outcomes Research program
continues to rank as one of the leading programs
in cardiovascular outcomes research in the
world. In 2013, Dr. Spertus and his team published
more than 65 peer-reviewed articles on the quality
of care and outcomes of patients with cardiovascular
disease. Beyond their ongoing efforts to promote the
importance of 1) patient-reported outcomes as a means
to better integrate patients’ symptoms, 2) function and
quality of life as outcomes in clinical trials, 3) quality
assessment and shared decision-making, their research
has recently focused on the development of an
infrastructure to support personalized medicine.
A nine-center study* in the setting of angioplasty was
able to support the execution of multivariable risk
models from the American College of Cardiology into
the flow of routine patient care. This study established
that this personalized approach improved
patients’ experiences with care, tailored treatment
with bleeding avoidance strategies to those who
most benefit, reduced bleeding complications
and enabled more efficient care with reduced
costs. In collaboration with investigators from Saint
Luke’s Marion Bloch Neuroscience Institute and the
University of California-Los Angeles, this methodology is
currently being extended to the treatment of acute
ischemic stroke, a historically undertreated condition.
Dr. Spertus, the Daniel J. Lauer/ University of Missouri
Endowed Chair in Metabolism and Vascular Research at
2013 Research Annual Repor t // Central Office of Research Administration
* Refer to page 59
Saint Luke’s Hospital of Kansas City, continues to lead an
NIH/NHLBI-funded training grant in outcomes research
and has collaborated with numerous faculty and trainees
throughout the country. The project is in collaboration
with University of Missouri – Kansas City. He continues
to serve as the deputy editor of Circulation: Quality of Care
and Outcomes. In recognition of his long-standing
commitment to the field, Dr. Spertus was awarded
the American Heart Association’s Distinguished
Achievement Award by the Quality of Care and
Outcomes Research Council. This award, given only once
every three years, recognizes excellence in scholarship,
mentorship, and significant contributions to the field.
Noted MAHI Investigators
Health Economics and Technology Assessment
(HETA)
Under the joint direction of David Cohen, M.D.,
director of cardiovascular research, and Elizabeth
Magnuson, Sc.D., the MAHI HETA group continues to
provide leadership to a large number of multicenter
studies designed to evaluate the cost-effectiveness of
novel cardiovascular technologies. During the past
year, the HETA group has focused on several clinical trials
evaluating alternative approaches to revascularization of
patients with complex multivessel coronary disease. One
such study was the FREEDOM* trial, a NIH-sponsored
clinical trial of PCI versus bypass surgery for patients
with diabetes and multivessel coronary disease and
demonstrated that bypass surgery led to improved longterm outcomes. The economic analysis led by the HETA
group demonstrated that bypass surgery was also a
highly cost-effective treatment for these patients.
These findings, which were published in Circulation,
serve to reinforce and strengthen current guidelines
that recommend bypass surgery as first-line therapy
for diabetic patients with multivessel coronary disease.
The quality of life component of the FREEDOM trial
was recently published in JAMA and demonstrated that
bypass surgery also led to improved quality of life
outcomes compared with PCI—particularly over the first
several years of follow-up.
In addition, the MAHI HETA group continues to
maintain an active portfolio of more than a dozen
health economic studies carried out alongside pivotal
NIH and private industry-sponsored clinical trials relating
to treatments for ischemic heart disease, atrial fibrillation,
valve disease, acute stroke, and peripheral vascular disease.
• Randall Thompson, M.D., conducted one of the more
unusual ongoing research projects at MAHI involving
the use of CT scanning to study heart and vascular
disease in the remains of ancient humans. CT
scans of mummies spanning more than 4,000 years from wide regions of the globe refute the thought that atherosclerosis is a disease caused by modern lifestyles. Dr. Thompson and his team recently published their findings in The Lancet. This project created intense
worldwide media interest including thousands of
newspapers, television and radio programs, as well as
periodicals such as Popular Science and Science Magazine. This unique work may ultimately help find missing risk factors and causes for this most common of diseases.
Over the next 12 months, the HETA group will be
completing a number of long-running studies including
studies investigating the cost-effectiveness of PCI versus
bypass surgery for patients with three-vessel and left
main disease (as part of the SYNTAX trial), renal artery
stenting versus optimal medical therapy for patients with
atherosclerotic renal artery stenosis (as part of the NIHsponsored CORAL* trial), and the novel anticoagulant
edoxaban versus warfarin for patients with atrial fibrillation
(as part of the ENGAGE-TIMI 48 trial).
• Suzanne Arnold, M.D., M.H.A., led a number of studies looking at quality of life in patients with
valvular heart disease, focusing specifically on patients with aortic stenosis considering transcatheter aortic valve replacement (TAVR) – a novel form of valve replacement. Along with Dr. Cohen, she has recently
developed and validated a statistical model to
identify patients who are at high risk for doing poorly with this new procedure. The information learned could help patients and their families make more * Refer to page 59
•
•
Paul Chan,* M.D., M.Sc., completed the most comprehensive and representative study of in-
hospital cardiac arrest survivors to date. Results were published in the New England Journal of Medicine. The study found that the three-year survival rate of cardiac arrest survivors was similar to that of patients with heart
failure, dispelling pessimistic attitudes on the life-
expectancy of survivors of in-hospital cardiac arrest. For this and his other recent seminal studies in cardiac arrest care, Dr. Chan was named the 2013 American Heart Association Dickinson W. Richards Memorial Lecturer on Resuscitation Science.
Sanjaya Gupta, M.D., is a cardiac electrophysiologist whose research program focuses on outcomes research
in patients with heart rhythm disorders. One of his current research interests is the intersection of cardiac electrophysiology and sleep apnea, which has led to the development of a novel method of
screening for sleep apnea in patients with
implantable cardioverter defibrillators (ICD). Based on analysis of more than 300 ICD recordings, Dr. Gupta and colleagues have developed an algorithm for prediction
of sleep apnea based upon patients with previously
diagnosed sleep apnea. The results of this study were
presented at the most recent Scientific Session of the
Heart Rhythm Society and are currently being
validated prospectively by enrolling patients in a prospective trial (NASSA-ICD) utilizing data collected
from ICDs during sleep studies in patients with undiagnosed sleep apnea. 2013 Research Annual Repor t // Central Office of Research Administration
9
informed treatment decisions. The results of this study were presented at the annual scientific sessions of the American College of Cardiology.
• Mikhail Kosiborod, M.D., continues to advance the field of cardiometabolism, and led a number of
impactful research studies in 2013.
Along with Suzanne Arnold,
M.D., M.H.A., he served as lead
author of the TERISA study, a
multi-national randomized clinical trial that evaluated the effectiveness
of ranolazine in reducing angina
among patients with Type 2 diabetes
and chronic stable coronary artery
disease. The results of the study were
presented as a late-breaking clinical
Mikhail Kosiborod, M.D.
trial at the American College of
Cardiology Congress in March and subsequently published in the Journal of the American College of Cardiology (JACC).
Dr. Kosiborod is also a pioneer in developing our understanding of the role of continuous glucose monitoring (CGM) technology in the management of
critically ill patients undergoing cardiac surgery. As principal investigator of an industry-sponsored study for its newly developed CGM system, Sentrino, Saint Luke’s MAHI was the first institution worldwide to study this device in patients after cardiac surgery. It was also the first time CGM was evaluated in patients
undergoing cardiac transplantation. The results
of this study were presented at the International Symposium on Intensive Care and Emergency Medicine in Brussels, Belgium, in March 2013.
•
James H. O’Keefe, M.D., continues to publish extensively in the areas of cardiovascular prevention, health and nutrition. Most recently, he has been focused on understanding the potential cardiovascular dangers of chronic excess endurance exercise – a syndrome termed “cardiac
overuse injury.” In collaborative projects with experts
from around the world involving tens of thousands of people followed for decades, he has found moderate intensity exercise is among the very best thing one can do for long-term cardiovascular health and longevity; excess exercise when done over years to
decades can predispose to heart problems over time. Several of Dr. O’Keefe’s widely cited papers this year deal with the CV benefits of coffee and tea, the importance of
fatty liver disease as a potent reversible CV risk factor, and a meta-analysis showing that the over-the-counter supplement L-carnitine improves prognosis after MI.
Lipid Diabetes Research
Center (LDRC)
Inflammation is now considered
an integral component of
atherothrombosis, leading to heart
attack, stroke, and peripheral
artery disease, especially in high
risk individuals, such as with
hypertension, smoking, elevated
cholesterol, and especially
diabetes.Yet to date no clinical trial
has been completed to determine
whether inhibiting inflammation
may reduce cardiovascular events.
Alan Forker, M.D.,
Medical Director, LDRC
The Lipid Diabetes Research
Center (LDRC) is involved in
two new multicenter trials trying to answer this question.
One is the CANTOS trial, utilizing canakinumab, a
human monoclonal antibody that neutralizes the bioactivity
of interleukin-1 beta, a primary cytokine promoting
inflammation. In addition to the standard medications
given post-myocardial infarction, quarterly canakinumab
subcutaneous injections will be given to patients with
continued elevation of inflammatory markers after MI. The
trial will enroll 17,000 patients worldwide in 1,400 study
centers with the goal to prevent recurrent cardiovascular
events.
The second trial is CIRT* (Cardiovascular Inflammation
Reduction Trial), funded by the NIH. This trial takes a
different approach than CANTOS—directly testing an
approved anti-inflammatory drug, methotrexate, given in
low dose, 15-20 mg orally once a week. Seven thousand
patients in the United States and Canada will be enrolled
in this multicenter trial with the goal of reducing recurrent
myocardial infarction and stroke in patients with a previous
MI or at high risk of a future cardiovascular event.
In addition to these novel studies of inflammation, the LDRC
continues to be involved in a large number of other studies
involving patients with hypertension, gout, obesity, and
several diabetes trials. One unique trial involves the use of a
tiny titanium metal tube placed under the skin to release a
long-acting form of the drug, exanatide, in order to improve
glucose control.
The LDRC added a new investigator this year, Fredric
Regenstein, M.D., a hepatologist, who is interested in testing
new approaches to treat hepatitis C.
Lipid and Diabetes Research:
18 active studies
276 patients enrolled
10
2013 Research Annual Repor t // Central Office of Research Administration
* Refer to page 59
Saint Luke’s Cancer Institute
Providing cancer patients access to leading clinical trials
Timothy J. Pluard, M.D.
Medical Director
Rakesh Gaur, M.D.,
M.P.H., FACP
Director of Medical
Oncology Research
The Saint Luke’s Cancer
Institute (SLCI) research
program assures access to an
extensive range of studies
in many cancer specialties.
Oncology patients treated at
Saint Luke’s Health System
metro facilities have the
opportunity to participate in
disease-specific clinical studies.
These include National Cancer
Institute (NCI) Cooperative
Research Group trials,
pharmaceutical industrysponsored research, and
investigator-initiated trials (IITs).
Through the evaluation of
promising investigational
treatments from these clinical
studies, Saint Luke’s oncology
patients and their physicians
are provided options for care
that otherwise would not be
available. SLCI partners with
major pharmaceutical and
biotech companies, as well
as prominent academic and
medical research institutions
throughout the United States.
During 2013, SLCI was a
contracted clinical site for a wide
variety of industry sponsored
trials, and it continually evaluates
new protocols to initiate at Saint
Luke’s Health System campuses.
Saint Luke’s is a leading member
of the Kansas City Clinical
Lowell Byers, M.D.
Oncology Program (KCCOP),
Director of Gynecologic
an NCI grant-funded initiative.
Oncology Research
For 30 years, the KCCOP has
facilitated regional patient access to national Cooperative
Research Group clinical trials. This aligns with and
advances the important national cancer strategy to
expand access to and increase enrollment in cancer
clinical trials.
Rakesh Gaur, M.D., KCCOP principal investigator,
works with the KCCOP leadership staff, member
institutions, and regional investigators who conduct
cancer research through a dynamic portfolio of treatment
and control trials.
2013 Highlights
•T
o provide greater responsiveness for cancer
patients and physician investigators and to support
growing study enrollment, SLCI expanded
research nurse coverage to full time at Saint Luke’s
East Hospital. This helps SLCI ensure the clinical
research team is active in identifying whether a research
trial is a good option for each patient.
•The Saint Luke’s Cord Blood Program has
collected 8,300 total units since the program’s
inception in 2008. This program serves as a
worldwide resource for children and adults who
need a stem cell transplant. Through 2013, 10 of
these units have been transplanted into patients with
acute myeloid leukemia, myelodysplastic syndrome,
and Fanconi’s anemia.
• Saint Luke’s Cell Processing Laboratory
continued processing blood samples for research
protocols, processed cells for a clinical stem
cell protocol for critical limb ischemia, and
submitted its first grant application for the
study of cord blood biopreservation.
• Timothy J. Pluard, M.D., joined SLCI in 2013 as both medical director and practicing clinician.
Dr. Pluard aims to elevate the Cancer Institute regionally and nationally, and aggressively pursue
research opportunities and clinical trials. Prior to joining Saint Luke’s, he was institutional principal investigator for the National Surgical Adjuvant Breast and Bowel Project. The National Cancer Institute (NCI) has recognized Dr. Pluard among the national top accruers in cooperative group trials.
• Rakesh Gaur, M.D., chief of hematology-oncology, continues to contribute numerous oncology
publications. Dr. Gaur serves on the National Cancer Institute (NCI) Leukemia Steering Saint Luke’s Cancer
Committee, which
Institute Research:
is primarily
responsible for 102 active studies
evaluating and approving clinical 309 patients enrolled
trials in leukemia and myelodysplastic 9 publications
syndrome.
5 abstracts/presentations
2013 Research Annual Repor t // Central Office of Research Administration
11
Saint Luke’s Marion Bloch
Neuroscience Institute
Kansas City’s leading neuroscience research center provides patients
with outcomes on par with the nation’s elite programs
Darren Lovick, M.D.
Co-director, Surgical
Charles Weinstein, M.D.
Co-director, Medical
(Interim)
The three pillars of Saint Luke’s
Marion Bloch Neuroscience Institute
are clinical research that brings the
latest in technology and therapy to
patients; public and professional
education; and clinical excellence.
Together, they guarantee excellent
outcomes for the care we provide
and attract exceptional, well-trained
clinicians who want to practice in a
vibrant and inquisitive environment.
In January 2013, the new
Neuroscience Institute opened with
88,000 square feet on six floors. It
includes 68 private rooms and an
18-bed neurointensive care unit.
The four neurosurgical suites and
two neurointerventional suites are
equipped with the latest technology.
Later in the year, the fourth floor
opened, adding an additional 20
private rooms.
The new facility has helped attract
subspecialty-trained physicians and
nurses to the Neuroscience Institute. Work is underway
to establish a neurocritical care service.
Clinical and translational research are part of each
Neuroscience Institute program. Many clinicians are
publishing sponsored or original research in peerreviewed journals and presenting on the national stage
at professional society meetings.
2013 Highlights
• S
aint Luke’s was honored to receive a very
generous $12 million gift from the Marion
and Henry Bloch Family Foundation to
support neuroscience programs and outcomes
research. The gift, the single largest ever received by
Saint Luke’s, will support expanded programming
for Saint Luke’s Marion Bloch Neuroscience
Institute, whose performance in neurology and
neurosurgery was recently recognized by U.S. News
& World Report, and for Saint Luke’s internationally
recognized center for outcomes research.
12
• D
arren Lovick, M.D., and Charles Weinstein,
M.D., were named co-directors of Saint Luke’s
Marion Bloch Neuroscience Institute.
• K
arin Olds, M.D., was named interim medical
director for the Stroke Program.
•
Collaborative projects are underway with Stanford University* and The Johns Hopkins Medical Institutions.* The Stanford project is developing technology to better identify which ischemic stoke patients might benefit from intra-
arterial stroke treatment. The Johns Hopkins project involves hemorrhagic stroke treatment options that could aid in recovery.
• N
eurological Interventional Radiologists Naveed
Akhtar, M.D., William Holloway, M.D.,
and Coleman Martin, M.D., presented at a
conference in London about their research on
retrieving clots for the treatment of stroke patients.
• T
he team was well represented at the
International Stroke Conference. Poster
presenters included: Joyce Dorssom, A.P.R.N.,
Brenda Jones, A.P.R.N., Katie Taylor, A.P.R.N.,
Debbie Summers, A.P.R.N., Marilyn Rymer, M.D.,
and Shelleen King, B.S.N. Debbie Summers
presented a platform presentation at the
International Stroke Conference Nursing
Symposium.
• D
onna Hunt, M.S.N., Mary Fowler, A.P.R.N.,
Traci Wheeler, B.S.N., and Rachel Malloy,
B.S.N., were platform presenters at the American
Association of Neuroscience Nurses 2013
National Conference.
• T
he March of Dimes 2013 Future of Nursing
Award recipients included two Neuroscience
Institute nurses.
Saint Luke’s Marion Bloch
Advanced
Practice: Debbie Neuroscience Institute Research:
Summers,
R.N., M.S.N.,
22 active studies
AHCNS-BC,
CNRN, SCRN,
129 patients enrolled
and Medical/
Surgical:
7 publications
Adrienne L.
Patterson, R.N.,
16 abstracts/presentations
M.S.M., CNRN.
2013 Research Annual Repor t // Central Office of Research Administration
* Refer to page 59
Saint Luke’s Midwest Ear Institute Research
Saint Luke’s Midwest Ear Institute
continues to be a national leader in
cochlear implants. In 2013, new,
thinner electrode arrays designed to
preserve the delicate structures of
the inner ear became available, as
well as new speech processors. With
this new technology, patients who
have better preservation of inner
ear structures have better speech
perception outcomes.
Robert Cullen, M.D.
Medical Director
2013 Highlights
•
The Ear Institute had the highest enrollment among 10 clinical sites in the United States for the study “Evaluation of the Nucleus Hybrid L24 Cochlear Implant System.” This device was submitted to the Food and Drug Administration (FDA) for a pre-market approval in 2013, and one of our subjects was asked to participate at the FDA panel. In November 2013, the FDA
Advisory Committee met and unanimously agreed
the device was safe and effective, and benefits outweighed risks.
• I n a related study, the 10 subjects who were
enrolled in the L24 Study have been able to
benefit from the advanced features of one
of the new cochlear implant processors, the
Cochlear America’s Nucleus 6 System. In a study
entitled, “Evaluation of the Nucleus® Hybrid™
L24 Cochlear Implant System, IDE Supplement:
Investigation of Nucleus 6 Sound Processor Signal
Processing Algorithms,” subjects can use the new
processor for a one month period. The subjects
are tested with their old processor and the new
processor initially, and then complete further
testing and questionnaires about the benefits they
receive after one month. At the conclusion, they
continue use of the new processor.
• E
ar Institute audiologists have designed an
investigator-initiated trial, “Optimal Hearing
Aid Parameters for Maximizing Performance in
Bimodal Cochlear Implant Users,” to determine
the best way to program a hearing aid with
a cochlear implant to make sound more
balanced. Many patients with cochlear implants
can benefit from a hearing aid in their contralateral
ears, giving them “bimodal” hearing and better
ability to hear in noise and to know the location of
sound. The results of this study will ensure patients
reach their maximum hearing potential.
2013 Research Annual Repor t // Central Office of Research Administration
13
Diagnostic and
Interventional Radiology
Focus on improved patient outcomes through investigator-initiated research
The Department of
Radiology continues to pursue
investigator-initiated research
projects with the goal of
improved patient outcomes.
Research efforts have resulted
in outside funding from the
biotechnology industry as
well as the Kansas Bioscience
Authority.
Jeff Kunin, M.D.
Department of Radiology
Chairman
2013 Highlights
• Jeff Kunin, M.D., continued
his investigator-initiated study, “The Role of
EarlyCDT®-Lung in the Management of
Pulmonary Nodules,” with co-investigators from the Departments of Radiology, Pulmonary Medicine, and Cardiology. This innovative study is evaluating
and correlating human autoantibodies
targeting lung cancer with pulmonary nodules found on computed tomography (CT) scans with a simple blood test called EarlyCDT®-
Lung. This blood test has the potential to distinguish benign from malignant pulmonary nodules. There
are 117 patients currently enrolled. The study is
funded by Health Diagnostic Laboratory Inc. (formerly Oncimmune), the Kansas Bioscience Authority, and Saint Luke’s Foundation.
•
•
In Dr. Borsa’s research, CT is being used to
evaluate the tilt of IVC filters. IVC filter tilt may have implications in filter efficacy as well as filter retrieval.
•
With the completion of enrolled-patient follow-up,
Interventional Radiology’s role in the ATTRACT*
(Acute Venous Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis) study led by Dr. Wible will come to a close. The NIH-funded, Phase III, multicenter clinical trial was designed to compare post-thrombotic syndrome (PTS), quality-of-life, cost-effectiveness, and safety
of pharmacomechanical catheter-directed thrombolysis (PCDT) versus conventional therapy for treatment of DVT.
• Saint Luke’s Hospital of Kansas City is the only hospital in the Kansas City region that employs radiologists with expertise in dedicated interpretation of thoracic imaging. Radiologist subspecialists, recognized at national and international levels, are utilizing two to three decades of imaging expertise to lead the multidisciplinary team of lung cancer experts in the 2013-initiated Saint Luke’s Hospital of Kansas City Lung Cancer Screening Program. Patients screened in this program receive low-dose chest CT scans and the advantage of diagnostic and treatment expertise from a host of medical specialists at Saint Luke’s.
Two interventional radiologists, Brandt C.
Wible, M.D., and John Borsa, M.D., FRCPC, are leading three investigator-initiated studies. Each research project focuses on inferior vena cava (IVC) filters.
• Dr. Wible’s first study is comparing filter removal success rates for two IVC filters
commonly used throughout Kansas City, with a goal of better understanding IVC filter designs to
aid with filter placement decisions. His second study strives to improve IVC filter retrieval rates in general by changing filter-placement and follow-up patient-scheduling practice patterns.
14
2013 Research Annual Repor t // Central Office of Research Administration
Interventional Radiology
Research:
5 active studies
404 patients enrolled
22 publications
21 abstracts/presentations
* Refer to page 59
Henry & Marion Bloch
Liver Disease Management
& Transplant Center
Multifaceted expertise caring for patients
The Henry & Marion Bloch Liver Disease
Management & Transplant Center provides
convenient access to comprehensive diagnostic and
therapeutic services to patients with liver disease and
hepatobiliary malignancy. In addition to its superb
team of physicians and health care professionals, the
center offers access to advanced treatment modalities,
including the opportunity to participate in clinical
research trials.
2013 HIGHLIGHTS
Hepatology & Liver Transplantation
The Liver Transplant Program received endorsement
of the team’s expertise by achieving certification
by the Centers for Medicare and Medicaid
(CMS). CMS certification status enables Saint Luke’s
to augment the exceptional care provided to patients
with end-stage liver disease through its comprehensive
program.
Saint Luke’s liver specialists and cardiologists
have discovered a compelling association
between non-alcoholic fatty liver disease
(NAFLD) and a high risk for cardiovascular
disease. Remarkable findings resulted from a
research study led by Liver Disease Management
Center gastroenterologists John Helzberg, M.D.,
and Rajiv Chhabra, M.D., with collaboration from
Saint Luke’s Mid America Heart Institute cardiologists
James O’Keefe, M.D., and Randall Thompson, M.D.
The research findings were published in Mayo Clinic
Proceedings.
disease. The center currently has five active clinical
trials evaluating new treatments for patients
with chronic hepatitis C and chronic liver
disease.
Vascular Access
Christie Gooden, M.D., transplant surgeon,
led a team evaluating a novel technique for
performing dialysis access grafts. The new
technique in the HeRO project allowed for dialysis
access grafts to be used sooner, decreasing the length
of time patients relied on catheters for dialysis and the
potential risk of infection. The findings were published
in The Scientific World Journal. Saint Luke’s is currently
the only center in the metropolitan region
performing HeRO grafts.
Renal Transplantation
• P
erformed the first combined kidney-liver
transplant at Saint Luke’s Hospital
• A
chieved 100 percent one-month patient and
graft survival and 96 percent six-month patient
and graft survival
Therapeutic Endoscopy
Saint Luke’s was selected as one of 12 U.S. research
sites to participate in a clinical trial evaluating a novel
endoscopic suturing device for the treatment of
obesity. The study, which will begin enrolling patients
in 2014, will be led by principal investigator Sreeni
Jonnalagadda, M.D., FASGE, section chief of
gastroenterology at Saint Luke’s.
Multicenter clinical research trials, led by Fredric
Regenstein, M.D., medical director of the Henry
& Marion Bloch Liver Disease Management &
Transplant Center, provide access to promising
innovative therapies for patients with chronic liver
2013 Research Annual Repor t // Central Office of Research Administration
15
Nursing
Staff has active role in collaborative projects impacting patient outcomes
Saint Luke’s Hospital nurses
are empowered to conduct
research to expand their
knowledge and implement
evidence-based strategies
to improve patient care.
Nurses can participate in nursing
research through a unit-based
program or independently.
2013 Highlights
Jacque Carpenter, R.N.,
Ph.D.
Nursing Research
Program Director
Saint Luke’s Hospital Nursing
Research Award
Effects of Night-Time Napping
on Attention and Satisfaction in Nurses on the Night Shift
Janet Emerson, R.N.
Saint Luke’s Hospital Evidence-Based
Practice Award
Improving Therapeutic Hypothermia
Marci Ebberts, R.N.
Unit-Based Research Program
The Unit-Based Nursing Research (UBR) Program
enables a team of staff nurses to collaborate on a
research project with the help of a team leader and
a research mentor. Each research team formulates
a researchable question by consensus, designs a
research project, and disseminates the results. This
program has increased the accessibility of research to
the bedside nurse.
Nursing Research Clinical Scholar Program
Initiated in 2012, the Nursing Research Clinical
Scholar (NRCS) Program continued to gain
momentum in 2013. This program is designed
for staff nurses who want to conduct investigatorinitiated clinical research. The NRCS program
provides multiple opportunities for a select group
of nurses to engage in scholarly research activities,
including development and implementation of a
research project.
Funds donated to Saint Luke’s Foundation provide
financial support that enabled the clinical scholars
to participate in nursing research activities. One of
the clinical scholars, Katie Jaschke, presented her
research at Saint Luke’s Hospital 2013 Research
Day. Her project was titled “Nurses’ Perceived
Barriers to and Suggested Interventions for
Providing High Quality End-of-Life Care.”
2013 Clinical Scholar Projects
• E
xamining the Effect of Cardiac Inpatients’
Perception of Fall Risk on the Intent to Participate
in Fall Prevention Interventions (Cheryl Radar,
CVICU)
• E
xploring What Motivates Individuals to Seek
Non-emergent Medical Treatment (Karen Mollus,
ED)
2013 Unit-Based Research Projects
• C
omparison of the Effects of Incentive Spirometry
on Dyspnea and Vital Capacity in Hospitalized
Pneumonia Patients (Yinghong Moore, E3)
• D
oes Speed of Drawing Mixed Venous Oxygen
Saturation Affect Results? (Katie Jaschke, CICU)
• C
omparison of Two Inpatient Educational
Methods in the Heart Failure Patient (Deb Negus,
Saint Luke’s College of Health Sciences)
• E
ffects of Patient Position on Pulmonary
Functioning Mechanically Ventilated Patients
(Donna Hunt, NSICU)
16
2013 Research Annual Repor t // Central Office of Research Administration
Nursing Research:
11 active studies
599 patients enrolled
2 publications
17 abstracts/presentations
Pharmacy
Acclaim at the regional, national, and international level
As a result of its investigator-initiated trials in 2013,
Saint Luke’s Health System Pharmacy Departments
made a number of important contributions
to the health system’s efforts to improve and
standardize patient care processes. Examples
include:
• Developing order sets in collaboration with Saint
Luke’s Care to optimize the use of intravenous
iron products and to direct the use of
procalcitonin as a guide for the discontinuation of
antimicrobial therapy in pneumonia patients
•W
orking with the Blood Bank and Neuroscience
Evidence-Based Practice Team to develop order
sets and modified dosing parameters for
four-factor prothrombin concentrate for
the management of warfarin-induced intracranial
hemorrhage
• Assessing the impact of pharmacy discharge
education on readmission rates for acute
myocardial infarction patients
•W
orking with the health system’s Antimicrobial
Stewardship Committee to develop mechanisms
to track longitudinal changes in antimicrobial
expenditures and their impact on resistance
pattern in our hospitals
Patrick Kelly, Pharm.D., and Nick Bennett,
Pharm.D., BCPS, won first place in the Allied
Health Division at Saint Luke’s Research Day
for their project titled “Impact of ProcalcitoninGuided Antibiotic Therapy in Pneumonia and COPD
Exacerbations in an Academic Community Hospital
Setting.”
Annie Pounders, Pharm.D.; Joe Blunck, Pharm.D.;
BCPS; and Jeannette Ploetz, Pharm.D., BCPS,
were recognized with the honorable mention
award in the Allied Health Division at Saint Luke’s
Research Day for their project titled “Evaluation of a
Pharmacist-Driven Protocol for the Discontinuation of
Inappropriate Stress Ulcer Prophylaxis.”
Jeff Little, Pharm.D., M.P.H., BCPS, received
the Distinguished Service Award from the New
Practitioner’s Section of the American Society of
Health-System Pharmacists at the ASHP Midyear
Clinical Meeting in Orlando in December 2013.
Greg Teale, Pharm.D., BCPS
Pharmacy Director,
Saint Luke’s Health System
Mark Woods, Pharm.D., FASHP, BCPS
Clinical Coordinator and Residency Program Director
2013 Highlights
Stephanie Burton, Pharm.D., BCPS; Kelly Galen,
Pharm.D., BCPS; and Kedra Blunck, Pharm.D.,
BCPS; won the Missouri Society of Health-System
Pharmacist (MSHP) Research and Education
Foundation’s Original Research Award for their
project “Evaluation of the Effect of Pharmacist Education
on Acute Myocardial Infarction Readmission Rates” at
the MSHP Annual Meeting in St. Louis. Saint Luke’s
Pharmacy Department has won this award 11 of
the past 13 years.
Emily Huedepohl, Pharm.D., and Mark Woods,
Pharm.D., FASHP, BCPS, were runners up for
the MSHP Research and Education Foundation
Original Research Award with their project titled
“Impact of Individualized Feedback on Medication
Barcode Scan Rates.”
Spencer Pummell, Pharm.D., BCPS, and Scott
Aldridge, Pharm.D., BCPS, were recognized as the
Outstanding Research Poster Presentation at the
Kansas Council of Health-System Pharmacists meeting in
Wichita for their project titled “Evaluation of Intravenous
Iron Sucrose Prescribing After the Implementation of a
Mandatory Order Set Across a Four Hospital System.”
2013 pharmacy residents
Pharmacy Research:
5 active studies
2,984 patients enrolled
2 publications
26 abstracts/presentations
2013 Research Annual Repor t // Central Office of Research Administration
17
Anesthesiology
UNIVERSITY OF MISSOURI – KANSAS CITY
■
SCHOOL OF MEDICINE
UMKC medical residents recognized for research achievements at regional and local levels
The academic Department of Anesthesiology at the
University of Missouri–Kansas City has grown to more
than 60 clinical faculty at three institutions (Saint Luke’s
Hospital of Kansas City, Truman Medical Center, and
Children’s Mercy Hospitals and Clinics), in addition
to five research faculty located at the University of
Missouri–Kansas City School of Medicine and Kansas
City University of Medicine and Bioscience.
Research and scholarly activity are requirements of
the anesthesiology residency review committee of the
Accreditation Council for Graduate Medical Education
(ACGME). Exploration of new knowledge keeps the
faculty on the leading edge of new advances, stimulates
inquiry, and promotes quality patient care. It is also an
important educational tool for residents’ learning and
for their academic development.
2013 Highlights
• E
.E. Fibuch, M.D., was president of
the Association of Midwest Academic
Anesthesiology Chairs (an association of 32
academic anesthesiology departments located in
the Midwest and extending into Canada).
• E
.E. Fibuch, M.D., headed the planning
committee for the 2013 Midwest Anesthesia
Residency Conference. 550 scientific abstracts
from 32 academic programs were presented.
• E
.E. Fibuch, M.D., was elected fellow
in the American College of Physician
Executives and the American Board of
Quality Assurance and Utilization Review
Physicians.
• T
he residency program underwent a RRC
site visit in February resulting in a five-year
accreditation (which was then extended to a 10year accreditation cycle in June 2013) without
citation.
• A
dam Reese, M.D., became the second
anesthesiology program director in the
history of the residency program as Dr. Fibuch
transitioned from this position after 36 years.
• C
hris Wang, M.D., fourth-year anesthesiology
resident, was awarded second place in the basic
science section at the 2013 Midwest Anesthesia
Residency Conference for his research entitled
“Differential Regulation of Behavioral Sensitivity
to Acute and Chronic Cocaine Administration
by Acid-Sensing Ion Channel 1a and 2 in Adult
Mice.”
• A
dam Reese, M.D., was accepted into the
Medical Management Masters program at
Carnegie Mellon University.
• A
ndrew Montalbano, M.D., fourth-year
anesthesiology resident, was awarded first place
in the basic science section of Saint Luke’s
Research Day for his research titled “Isoflurane
Enhances the Moonlighting Activity of GAPDH:
Implications for GABAa Receptor Trafficking.”
E.E. Fibuch, M.D., CPE, CHCQM, FACPE,
FABQAURP
Professor and Chairman
• A
dam Reese, M.D., was certified by the
American College of Physician Executives as
a physician executive (CPE).
• E
.E. Fibuch, M.D., co-directed the first
Physician Leadership Program for the
University of Missouri—Kansas City. It is a
conjoint leadership training program sponsored by
the School of Medicine and the Bloch School of
Management designed to train the next generation
of physician leaders.
18
2013 anesthesiology residents
2013 Research Annual Repor t // Central Office of Research Administration
Women & Children
Research enhances comprehensive perinatal and neonatal services
Saint Luke’s Health System delivers more babies than
any other health system in Kansas City, and its flagship,
Saint Luke’s Hospital, has delivered babies for more
than a century. Saint Luke’s Hospital’s maternal fetal
medicine offers the area’s highest level of perinatal care
for expectant moms who are considered high-risk and
a level IIIb NICU, which promotes best outcomes for
tiny babies.
of infants with severe ROP. Findings will enable
clinicans to identify factors that may increase the risk
of blindness and other adverse outcomes in premature
infants.
High-Risk Obstetrics
George Lu, M.D., Perinatologist
Removal Versus Retention of Cerclage in
Preterm Premature Rupture of Membranes
Neonatology
Katherine Claflin, M.D., Neonatologist
Study Registry for Severe Retinopathy and
Treatment on Visual Outcomes of Premature
Neonates
Several recent studies have generated significant
concern about how to best prevent retinopathy of
prematurity (ROP), and how to best treat severe ROP
when it develops. This study’s purpose is to monitor
the influence of the prescribed care on outcomes and
determine what factors influence the visual outcomes
This national study concluded enrollment at the end
of 2013. The research project explored the question of
whether to remove a cerclage after premature preterm
rupture of membranes (PPROM). This question is one
of the unresolved controversies in obstetrics because
few studies are available or have conflicting results. The
combination of PPROM in a patient with cerclage in
place is a rare complication, making it difficult to study
in medical centers not staffed by perinatologists.
Spiritual Wellness
Clinical Pastoral Education Advanced Ministry
Saint Luke’s Health System’s Clinical Pastoral
Education Program requires its chaplain residents
to conduct a research project addressing a particular
health and spirituality subject. These projects offer a
theologically informed spiritual care strategy for the
care of patients, family, and staff directly affected by
a particular health-related subject, such as trauma,
stroke, heart conditions, palliative care, cancer, or
ethical issues.
In 2013, Chaplain Residents Kristin Austin, Phyllis
Flory, Tim Maguffee, and Judy Sneegas completed
a research study exploring how nurses’
perceptions of the chaplain’s role impact the
integration of chaplain services and other
Spiritual Wellness resources into patient,
family, and staff care. The study identified a gap
between nurses’ perception of the role of chaplain
and how chaplains perceive their role as health care
professionals. The study had three recommendations:
• T
he Spiritual Wellness Department should provide
continuing education to all members of patient care
teams about when, why, and how to make referrals to
chaplains.
• Chaplains should be integrated into patient care
teams, including attending rounds, discharge
planning, team meetings, etc. Chaplains should
be intentional about developing relationships with
nursing staff.
• T
he Spiritual Wellness Department should provide
online resources that address nurses’ issues of
concern, such as spiritual resources related to
different faith traditions.
Marc Giedinghagen, D.Min.
Director of Clinical Pastoral Education
2013 Research Annual Repor t // Central Office of Research Administration
19
Saint Luke’s Hospital
Institutional Review Board
Group protects human subjects from undue risk during investigations
The Saint Luke’s Hospital Institutional Review Board
(IRB) reviews research involving human subjects.
Its goals are protecting human subjects from undue
risk during the course of scientific investigations and
fulfilling requirements of federal regulations governing
such research. IRB meetings occur twice monthly
January through October and once monthly in
November and December.
Saint Luke’s IRB—Very Responsive
The Saint Luke’s Hospital IRB is known for being
very responsive and for its prompt turnaround.
Submission deadlines for IRB meetings are typically
three weeks prior to each meeting. This amount of time
allows for processing of the studies in the IRB office,
distribution of information to IRB members, and
review by members prior to the meetings. Following
IRB meetings, correspondence regarding status of IRB
review is normally completed within a few days.
Pharmaceutical and medical device companies often
comment on the efficiency of Saint Luke’s IRB and
the four-week turnaround of IRB decisions, which is
almost unheard of in the research industry.
The IRB is composed of individuals devoted to
assuring the ethical conduct of research within
Saint Luke’s Health System.
IRB Members
• Alan Forker, M.D., Chair
• Diana Dark, M.D., Vice Chair
• Sharon Bell, R.Ph.
• Jeremy Burd, M.D.
• Jacque Carpenter, R.N., Ph.D.
• Jennifer Elliott, M.D.
• Rakesh Gaur, M.D.
• Karl Hanson, M.D.
• Marilyn Horn, CIP, IRB Administrator
• Rev. Jerry Kolb
• Anthony Magalski, M.D.
• Ellen McDowell, R.N., M.S.A.
• Henry Randall, M.D.
• Jim Silber, community member
• Sandy Silva, Esq.
Number of Active Studies 2009–2013
450
400
• Marci Ebberts, R.N., B.S.N., C.C.R.N. (alternate for Jacque Carpenter)
• Tarris Rosell, Ph.D. (alternate for Sandy Silva)
350
300
Affiliates for review of research at their
respective sites:
250
200
• Kathy Harms, Ph.D., Crittenton Children’s Center
150
• Shauna Todd, R.N., Saint Luke’s East Hospital
100
• Jeff Eye, R.N., M.S.N., Saint Luke’s North
Hospital
50
0
2009
20
Alternate:
2010
2011 2012
2013
• J ulia Woods, R.N., M.S.N., Saint Luke’s South
Hospital
2013 Research Annual Repor t // Central Office of Research Administration
2013 Research Day
Saint Luke’s Hospital researchers earn recognition for their work at annual event
Saint Luke’s Hospital 2013 Research Day, held May 3,
showcased a variety of projects, including:
• 1
5 from medical residents and fellows
• 7 by Pharm.D. residents
• 8 by nursing teams (an additional 13 uncompleted projects were introduced by displays)
• 4
from medical staff/allied health professionals
The purpose of Research Day is to showcase studies
conducted by medical residents and fellows, along
with projects of professional staff. The high-quality,
intellectually stimulating work of many talented
professionals was highlighted and encompassed
numerous specialties, such as:
• Anesthesiology
• C
ardiovascular
• C
ritical Care
• G
astroenterology
• I nternal Medicine
• N
eurology
• Nursing
• O
ncology
• P
harmacology
• Radiation Oncology
Both basic research (“bench research” in a lab setting)
and clinical research (research with human subjects)
were represented. Many of these Saint Luke’s
research projects competed nationally and
received awards within their specialties.
2013 Research Annual Repor t // Central Office of Research Administration
21
2013 Research Day
Winners
Basic Research
First Place — Andrew Montalbano, M.D.,
Anesthesiology Resident
Honorable Mention — Alisa Likhitsup, M.D.,
Internal Medicine Resident
GAPDH-Mediated GABBA Receptor
Trafficking Enhanced by Volatile Anesthetics
Staining for Liver Oxidative Stress in Obese
Mouse Module
Clinical Research
22
First Place — Natalie Jayaram, M.D.,
Cardiology Outcomes Research Fellow
Honorable Mention — Faraz Kureshi, M.D.,
Cardiology Outcomes Research Fellow
Hospital Variation in Survival for Pediatric
In-Hospital Cardiac Arrest: A Report from Get
With the Guidelines – Resuscitation
Variability in Patient Misperceptions on the
Indications and Benefits of PCI in Stable Coronary
Artery Disease Within and Across Centers
2013 Research Annual Repor t // Central Office of Research Administration
Allied Health
First Place — Patrick M. Kelley, Pharm.D.,
Pharm.D. Resident
Honorable Mention — Annie Pounders, Pharm.D.,
Pharm.D. Resident
Impact of Procalcitonin-Guided Antibiotic
Therapy in Pneumonia and COPD
Exacerbations in an Academic Community
Hospital Setting
Evaluation of a Pharmacists-Driven Protocol
for the Discontinuation of Inappropriate Stress
Ulcer Prophylaxis
Nursing Research
Nursing Evidence-Based Practice
First Place — Janet Emerson, R.N.,
Principal Investigator
First Place — Marci Ebberts, R.N., B.S.N., CCRN
Improving Therapeutic Hypothermia
Effect of Napping on Perception of Sleepiness
and Selective Attention/Concentration in Nurses
on Night Shift
2013 Research Annual Repor t // Central Office of Research Administration
23
Scholarly
Activities,
Publications
and
Abstracts &
Presentations
Saint Luke’s investigators’ work
contributes to leading-edge treatment
options for patients and the body
of knowledge for clinicians around
the world.
24
2013 Research Annual Repor t // Central Office of Research Administration
2013 Scholarly Activities
Allen KB. Annals of Thoracic Surgery. Invited
Reviewer.
Butrick C. Obstetrics and Gynecology Journal,
Reviewer.
Allen KB. Circulation. Invited Reviewer.
Chan P. Abstract Grading Committee, American
College of Cardiology Scientific Sessions. Grader.
Allen KB. FDA. Circulatory Device Panel Member.
Allen KB. INNOVATIONS. Invited Reviewer.
Allen KB. International Society of Minimally
Invasive Cardiothoracic Surgeons. Board of Directors.
Allen KB. Journal of Cardiovascular & Thoracic
Surgery. Invited Reviewer.
Bateman T. American Society of Nuclear Cardiology.
Scientific Meeting Planning Committee.
Bateman T. International Conferences of Nuclear
Cardiology. Program Planning Committee.
Bateman T. Subspecialty Board on Cardiovascular
Disease, American Board of Internal Medicine.
Member.
Bennett N. American Society of Health-System
Pharmacists, Section of Clinical Specialists and
Scientists, Clinical Leadership Committee, Member.
Bennett N. American Society of Health-System
Pharmacists, Student Society Advisor, Drake University
School of Pharmacy.
Borsa JJ. American Journal of Radiology, Invited
Manuscript Reviewer.
Borsa JJ. Journal of Endovascular Therapy, Invited
Manuscript Reviewer.
Borsa JJ. Journal of Vascular and Interventional
Radiology, Invited Manuscript Reviewer.
Borsa JJ. Radiology, Invited Manuscript Reviewer.
Borsa JJ. Society of Interventional Radiology,
Technology Assessment Committee, Member.
Buchanan DM. Circulation: Cardiovascular Quality
and Outcomes. Ad Hoc Reviewer.
Butrick C. American Journal of Obstetrics and
Gynecology, Reviewer.
Butrick C. International Urogynecology Journal,
Reviewer.
Butrick C. Journal of Female Pelvic Medicine and
Reconstructive Surgery, Reviewer.
Butrick C. Journal of Sexual Medicine, Reviewer.
Butrick C. Journal of Urology, Reviewer.
Chan P. Abstract Grading Committee, American
Heart Association Resuscitation Science
Conference. Grader.
Chan P. Abstract Grading Committee, American
Heart Association Scientific Sessions. Grader.
Chan P. American College of Cardiology National
Cardiovascular Disease Registry (NCDR) Science
and Quality Oversight Committee. Committee
Member.
Chan P. American College of Cardiology PINNACLE
Registry Research and Publications Committee.
Committee Member.
Chan P. American Heart Association Get with the
Guidelines Adult Research Task Force. Chair.
Chan P. American Heart Association Get with the
Guidelines Steering Committee. Committee Member.
Chan P. American Heart Association Get with the
Guidelines-Resuscitation. Vice-Chair of Research.
Chan P. American Heart Association Social
Determinants of Health Committee. Member.
Chan P. American Heart Journal. Invited Journal
Reviewer.
Chan P. American Journal of Cardiology. Invited
Journal Reviewer.
Chan P. Chest. Invited Journal Reviewer.
Chan P. Circulation. Invited Journal Reviewer.
Chan P. Conference Planning Committee for
American Heart Association Conference on Quality
of Care and Outcomes. Committee Member.
Chan P. Critical Care Medicine. Invited Journal
Reviewer.
Chan P. European Heart Journal. Invited Journal
Reviewer.
Chan P. Journal of the American College of
Cardiology. Invited Journal Reviewer.
Chan P. Journal of the American Medical
Association. Invited Journal Reviewer.
Chan P. New England Journal of Medicine. Invited
Journal Reviewer.
2013 Research Annual Repor t // Central Office of Research Administration
25
Chan P. Resuscitation. Invited Journal Reviewer.
Chhatriwalla AK. Cardiovascular Revascularization
Medicine. Ad Hoc Reviewer.
Chhatriwalla AK. Circulation: Quality and Outcomes
Research. Ad Hoc Reviewer.
Chhatriwalla AK. Clinical Cardiology. Ad Hoc
Reviewer.
Chhatriwalla AK. International Journal of Cardiology.
Ad Hoc Reviewer.
Chhatriwalla AK. Journal of Cardiology and Therapy.
Editorial Board.
Chhatriwalla AK. Trends in Cardiovascular Medicine.
Ad Hoc Reviewer.
Cohen DJ. ACCF/AHA Task Force on Practice
Guidelines/Task Force on Performance Measures
Cost Methodology Paper. Peer Reviewer.
Cohen DJ. AHA Council on Clinical Cardiology,
Interventional Cardiovascular Care Committee.
Member.
Cohen DJ. American Heart Journal. Editorial Board.
Cohen DJ. Cardiology Today Intervention. Editorial
Board.
Cohen DJ. Cardiovascular Intervention Medicine.
Editorial Board.
Cohen DJ. Circulation. Editorial Board.
Cohen DJ. Circulation. Peer Reviewer.
Cohen DJ. Circulation: Cardiovascular Quality and
Outcomes. Editorial Board.
Cohen DJ. Coronary Artery Disease. Editorial Board.
Cohen DJ. Research and Publications Committee,
ACC-STS Transcatheter Valve Therapy Registry.
Member.
Cohen DJ. Steering Committee, TRANSLATE-ACS
Trial (DCRI). Member.
Day K. Greater Kansas City Society of HealthSystem Pharmacists, Immediate Past-President and
Board of Directors.
Friedell M. ACGME Association of Program
Directors in Surgery (APDS) Milestones
Committee, Member.
Friedell M. American College of Surgeons
Assessment of Preparation for Intern Readiness in
Surgery (ASPIRES) Committee, Member.
Friedell M. APDS Nominating Committee, Chairman.
Friedell M. Journal of Surgical Education, Editorial
Board.
Friedell M. Little Red Book Revision Committee,
American College of Surgeons Division of Education,
Member.
Friedell M. Program for Chiefs of Clinical Services,
Harvard School of Public Health.
Friedell M. Surgical Council on Resident Education
(SCORE), APDS representative.
Gaddis G. Academic Emergency Medicine, Senior
Associate Editor, Decision Editor, and Reviewer.
Gaddis G. American Journal of Emergency
Medicine, Reviewer.
Cohen DJ. EuroIntervention Journal. Editorial Board.
Gaddis G. European Journal of Emergency
Medicine, Reviewer.
Cohen DJ. Journal of Cardiovascular Translational
Research. Editorial Board.
Gaddis, G. Journal of Emergency Medicine, Reviewer.
Cohen DJ. Journal of the American College of
Cardiology. Peer Reviewer.
Cohen DJ. Journal of the American College of
Cardiology: Cardiovascular Interventions. Editorial
Board.
Cohen DJ. Journal of the American Medicine
Association. Peer Reviewer.
Cohen DJ. New England Journal of Medicine. Peer
Reviewer.
26
Cohen DJ. Publications Committee, TRANSLATEACS Trial (DCRI). Member.
Gaddis, G. Med Ed Portal, Reviewer.
Gaddis, GM, Graham CA. 7th Mediterranean
Emergency Medicine Congress, Research Abstracts
Co-Chair.
Gaddis, GM. American Academy of Emergency
Medicine Scientific Assembly 2013, Research Abstract
Contest Judge.
Gupta, S. Heart Rhythm Society 34th Annual
Scientific Sessions. Section Chair.
2013 Research Annual Repor t // Central Office of Research Administration
Haideri N, American Society of Clinical Oncology,
Virtual Mentor.
Kosiborod M. ACTION-Get With the Guidelines
Research & Publications Committee. Member.
Kosiborod M. American Heart Association Council
on Nutrition, Physical Activity and Metabolism
(NPAM) Leadership and Conference Planning
Committee. Member.
Kosiborod M. American Heart Association Council
on Nutrition, Physical Activity and Metabolism
(NPAM) Leadership and Conference Planning
Committee. Chair.
Kosiborod M. American Heart Association National
Advocacy Committee. Member.
Kosiborod M. American Heart Association’s
Committee on Scientific Sessions Planning. QCOR
Council Chair.
Kosiborod M. KEEP (Kidney Early Evaluation
Program) of the National Kidney Foundation,
Steering Committee. Member.
Kosiborod M. NCQA/AMA-PCPI Joint Diabetes
Expert Panel. Panel Participant.
Kosiborod M. The Endocrine Society’s Clinical
Practice Guideline on the Management of
Hyperglycemia in Hospitalized Patients in a NonCritical Care Setting. Member.
Kosiborod M. Writing Group: “Contributory Risk
and Management of Comorbidities of Hypertension,
Obesity, Diabetes, Hyperlipidemia and Metabolic
Syndrome in Chronic Heart Failure A Scientific
Statement from the American Heart Association”.
Member.
Kosiborod M. Writing Group: “Prevention of
Cardiovascular Disease in People with Type 2
Diabetes in Light of New Evidence: A Scientific
Statement from the American Heart Association
and the American Diabetes Association”. Member.
Lamar J. Greater Kansas City Society of HealthSystem Pharmacists, Program Chair and Board of
Directors.
Little J. American Society of Health-System
Pharmacists, Political Action Committee Advisory
Group.
Little J. American Society of Health-System
Pharmacists, Section of Practice Managers, Manager
Development Section Advisory Group.
Little J. American Society of Health-System
Pharmacists, Student Society Advisor, Creighton
University School of Pharmacy.
Little J. Kansas Council of Health-System
Pharmacists, Treasurer and Board of Directors.
Little J. Kansas Pharmacy Technician Advisory
Group, Board member.
Magalski A. Advanced Heart Failure/Transplant
Fourth Year Fellowship Program. Director.
Marso S. American College of Cardiology: i2LIVE
Program Committee. Member.
Marso S. Cardiothoracic Surgical Trials Network
(CSTN) Glucose Control Pre-Protocol Development
Committee. Member.
Marso S. Carotid Artery Revascularization and
Endarterectomy (CARE) Registry Committee.
Member.
Marso S. SCAI Task Force on PCI Quality. Member.
Marso S. State of Missouri Time Critical Diagnosis
(TCD) Committee. Chairman.
Massey L. American Society of Health-System
Pharmacists, Section of Practice Managers, Leadership
Development Advisory Group Member.
Massey L. American Society of Health-System
Pharmacists, Student Society Advisor, University of
Kansas School of Pharmacy.
Massey L. Kansas Council of Health-System
Pharmacists, Chair, Governmental Affairs Committee
Member.
Massey L. Kansas Pharmacy Technician Advisory
Group, Chair.
Maulik D. Central Association of Obstetrics and
Gynecology, Board Member.
Maulik D. Journal of Maternal, Fetal and Perinatal
Medicine, Editor-in-Chief.
Maulik D. Maternal Fetal Medicine Fellowship
Program (ABOG Accredited), Program Director.
Maulik D. Maternal Fetal Medicine Section, The
Global Library of Women’s Medicine, Sapiens
Global Library Inc. UK, Consulting editor.
Milburn L. National Kidney Disease Education
Program, Member, Laboratory Working Group.
2013 Research Annual Repor t // Central Office of Research Administration
27
O’Keefe JH Jr. “For the Heart” Publication from
Cardiovascular Consultants. Ten-time winner
of Healthcare Advertising Awards National
Competition. Editor in Chief.
O’Keefe JH Jr. Enhance Magazine. Contributor.
O’Keefe JH Jr. Journal of the Missouri State Medical
Association. Editorial Board.
O’Keefe JH. Living Wellness Kansas City. Contributing
Author.
Repp K. Missouri Society of Health-System
Pharmacists Research and Education Foundation,
Board of Directors.
Robke J. American Society of Health-System
Pharmacists Research and Education Foundation,
Immunization Grant Advisory Panel, Member.
Rosado de Christenson ML. American Journal of
Roentgenology, Manuscript Reviewer.
Rosado de Christenson ML. American Roentgen Ray
Society, Introduction to Academic Radiology: Developing
a Successful Mentoring Relationship.
Rosado de Christenson ML. American Roentgen Ray
Society, President-Elect; Executive Committee Member;
Executive Council Member; Ex Officio Member: CME
Review Approval Subcommittee, Program Committee,
Outcomes Committee, Global Relations Committee.
Rosado de Christenson ML. Mallinckrodt Institute of
Radiology, Visiting Professor.
Rosado de Christenson ML. Radiologic Pathology
Course, American Institute for Radiologic
Pathology, Visiting Professor.
Rosado de Christenson ML. Society of Thoracic
Radiology, President; Chair, Program Committee;
Member, CME Review Committee.
Spertus JA. ACC NCDR Data Quality Work Group.
Member.
Spertus JA. ACC NCDR Scientific Oversight
Committee. Member.
Spertus JA. ACC Oversight Committee on the
Development of CMS Outcomes Measures for
Quality. Chair.
Spertus JA. ACC Presidential Task Force
on Performance Assessment, Recognition,
Reinforcement, and Reward (PAR3 Task Force).
Member.
28
Spertus JA. ACC/AHA Writing Committee for the
Stable Ischemic Heart Disease Guidelines. Member.
Spertus JA. AMA PCPI/ACC/AHA Collaboration
for the Determination of Performance Measures
of Quality in Hypertension, Angina and Congestive
Heart Failure. Co-Chair.
Spertus JA. American College of Cardiology/
Center for Medicare and Medicaid Services 30-day
Outcomes Working Group for PCI. Member.
Spertus JA. American College of Cardiology/
Center for Medicare and Medicaid Services 30-day
Outcomes Working Group for ICD. Member.
Spertus JA. American Heart Association QCOR
Council Nominating Committee. Chair.
Spertus JA. American Heart Association QCOR
Council Young Investigator Committee. Chair.
Spertus JA. BC Centre for Improved Cardiovascular
Health Advisory Board. Member.
Spertus JA. Circulation. Associate Editor.
Spertus JA. Circulation: Cardiovascular Quality and
Outcomes. Deputy Editor.
Spertus JA. Executive Steering Committee, VA CHF
QUERI. Member.
Spertus JA. HMO Research Network Cardiovascular
Disease Research Network (HMORN CVRN)
External Collaborations and Advisory Committee.
Member.
Spertus JA. International Scientific Advisory
Committee for the Canadian Cardiovascular
Outcomes Research Team (C-CORT). Member.
Spertus JA. National Quality Forum’s Technical
Advisory Panel (TAP) for Heart Disease in its
Standardizing Ambulatory Care Performance
Measures Project. Member.
Spertus JA. NHLBI Protocol Review Committee and
DSMB: PROMISE Trial. Member.
Spertus JA. Steering Committee IHD QUERI C3P
Facilitated Cardiology Consultation Project. Member.
Spertus JA. United Healthcare National Cardiac Care
Scientific Advisory Board. Member.
Spertus JA. Veterans Affairs Ischemic Heart Disease
QUERI Executive Committee. Member.
Stevens TL. American Heart Association. National
Spokesperson.
2013 Research Annual Repor t // Central Office of Research Administration
Stevens TL. Heart Health Advisory Board for Woman’s
Day. Member.
Stevens TL. NHLBI Founding Heart Truth Partner.
Stevens TL. NHLBI Heart Truth Community Action
Program Grant. Recipient.
Stevens TL. The National Coalition for Women with
Heart Disease Scientific Advisory Council. Member.
Stewart JR. Annals of Thoracic Surgery. Ad Hoc
Reviewer.
Woods M. American Society of Health-System
Pharmacists Research and Education Foundation,
Excellence In Residency Awards Evaluation Panel,
Member.
Woods M. Board of Pharmaceutical Specialties
Oncology, Board Member.
Woods M. Kansas Council of Health System
Pharmacists Research and Education Foundation,
Board of Directors, Chair.
Woods M. United States Food and Drug
Administration, Drug Safety and Risk Management
Committee, Member.
Thompson RC. American College of Cardiology
Coding Task Force. Vice Chair.
Thompson RC. American Medical Association CPT
Editorial Panel. Alternate Advisor for Cardiology.
Thompson RC. American Society of Nuclear
Cardiology Scientific Sessions Program Committee.
Member.
Thompson RC. American Society of Nuclear
Cardiology. Board of Directors.
Thompson RC. Egyptian Journal of Cardiology,
The Anatomical Record, and Global Heart. Ad Hoc
Reviewer.
Thompson RC. International Congress of Nuclear
Scientific Sessions. Program Chair.
Thompson RC. Journal of Nuclear Cardiology. Editorial
Board.
Wall T, National Radiation Oncology Registry,
Radiation Oncology Institute and American Society
for Radiation Oncology, Executive Committee member.
Wible BC. RADPrimer Radiology Learning Portal,
Vascular and Interventional Radiology Section.
Amirsys electronic publication, Section Team Leader and
Editor.
Wible BC. RADPrimer Radiology Learning Portal.
Amirsys electronic publication, Content Contributor.
Wible BC. STATdx Radiologic Decision Support,
Vascular and Interventional Radiology Section.
Amirsys electronic publication, Content Contributor
Wimmer A. Circulation: Arrhythmias and
Electrophysiology. Reviewer.
Wimmer A. Europace. Reviewer.
Wimmer A. Heart Rhythm. Reviewer.
2013 Research Annual Repor t // Central Office of Research Administration
29
2013 Publications
ANESTHESIOLOGY
Elliott J. Fibuch EE. Endocrine Effects Of Chronic
Opioids Therapy: Implications For Clinical
Management. An Invited Review. 2013 Pain Management
3(3) 237-246.
Fibuch EE, Van Way C. Benchmarking. 2013. Physician
Executive Journal Jan-Feb pp28-32.
Fibuch EE, Ahmed A. Indexing Performance Measures.
2013 Physician Executive Journal. Nov/Dec pp38-43.
Guo ML, Xue B, Jin DZ, Mao LM, Wang JQ (2013)
Dynamic Downregulation Of Nogo Receptor
Expression In The Rat Forebrain By Amphetamine.
Neurochem Int 63:195-200. PMC3735811.
Jiang Q, Wang CM, Fibuch EE, Wang JQ, Chu XP.
Differential Regulation Of Locomotor Activity
To Acute And Chronic Administration In AcidSensing Ion Channels 1 A And 2 In Adult Mice. 2013.
Neuroscience. 246:170-178.
Jin DZ, Guo ML, Xue B, Fibuch EE, Choe ES, Mao
LM, Wang JQ (2013) Phosphorylation and Feedback
Regulation of Metabotropic Glutamate Receptor 1 by
Camkii. J Neurosci 33:3402-3412. PMC3711744.
Jin DZ, Guo ML, Xue B, Mao LM, Wang JQ (2013)
Differential Regulation of Camkiiα Interactions With
Mglur5 and NMDA Receptors by Ca2+ in Neurons. J
Neurochem 127:620-631.
Mao LM, Reusch JM, Fibuch EE, Liu Z, Wang JQ (2013)
Amphetamine Increases Phosphorylation Of MAPK/
ERK At Synaptic Sites In The Rat Striatum and
Medial Prefrontal Cortex. Brain Res 1494:101-108.
PMC3546198.
Mao LM, Diaz, Diaz, JA, Fibuch EE, Wang JQ (2013)
Regulation of Phosphorylation of Synaptic And
Extrasynaptic Glua1 AMPA Receptors In The Rat
Forebrain by Amphetamine. Eur J Pharmacol 715:164171.
Mao LM, Guo ML, Jin DZ, Xue B, Wang JQ (2013)
Group III Metabotropic Glutamate Receptors And
Drug Addiction. Frontiers of Medicine 7:445-451.
Newell B, Fibuch EE, McCartney M. Simulations
in Anesthesiology: A Key Element In The New
Recertification Process. 2013. Missouri Medicine.
March/April, pp 139-141.
30
Newell B, Fibuch EE, McCartney M. Simulations
in Anesthesiology: A Key Element In The New
Recertification Process. 2013. Missouri Medicine.
March/April, pp 139.
CANCER INSTITUTE
Ma CX, Suman VJ, Goetz M, Haluska P, Moynihan
T, Nanda R, Olopade O, Pluard T, Guo Z, Chen HX,
Erlichman C, Ellis MJ, Fleming GF. A Phase I Trial Of
The IGF-1R Antibody Cixutumumab In Combination
With Temsirolimus In Patients With Metastatic
Breast Cancer. Breast Cancer Res Treat, 2013 May;
139(1): 145-53. doi: 10.1007/s10549-013-2528-8. Epub
2013 Apr 19.
Miranda RN, Aladily TN, Prince HM, Kanagal-Shamanna
R, de Jong D, Fayad LE, Amin MB, Haideri N, Bhagat G,
Brooks GS, Shifrin DA, O’Malley DP, Cheah CY, Bacchi
CE, Gualco G, Li S, Keech Jr JA, Hochberg EP, Carty
MJ, Hanson SE, Mustafa E, Sanchez S, Manning Jr JT,
Xu-Monette ZY, Miranda AR, Fox P, Bassett RL, Castillo
JJ, Beltran BE, de Boer JP, Chakhachiro Z, Ye D, Clark D,
Young KH, Medeiros LJ. Breast Implant–Associated
Anaplastic Large-Cell Lymphoma: Long-Term
Follow-Up of 60 Patients. Journal of Clinical Oncology,
2013 December 09; Published Ahead of Print as 10.1200/
JCO.2013.52.7911.
Roop RP, Naughton MJ, Van Poznak C, Schneider JG,
Lammers PE, Pluard TJ, Johnson F, Eby CS, Weilbaecher
KN. A Randomized Phase II Trial Investigating the
Effect of Platelet Function Inhibition on Circulating
Tumor Cells in Patients With Metastatic Breast
Cancer. Clinical Breast Cancer, 2013; 13(6): 409-15.
Sessa C, Shapiro GI, Bhalla KN, Britten C, Jacks KS, Mita
M, Papadimitrakopoulou V, Pluard T, Samuel TA< Akimov
M, Quadt C, Fernancez-Ibarra C, Lu H, Bailey S,
Chica S, Banerji U. First-in-Human Phase I DoseEscalation Study of the HSP90 Inhibitor AUY922 in
Patients with Advanced Solid Tumors. Clin Cancer
Res, 2013 Jun 11.
Youland RS, Schomas DA, et al. Changes In
Presentation, Treatment, And Outcomes Of Adult
Low-Grade Gliomas Over The Past Fifty Years. Neuro
Oncol, 2013 Aug; 15(8):1102-1110.
Youland RS, Schomas DA, et al. Prognostic Factors And
Survival Patterns In Pediatric Low-Grade Gliomas
Over 4 Decades. Journal of Pediatric Hematology/
Oncology, 2013 Apr; 35(3):197-205.
2013 Research Annual Repor t // Central Office of Research Administration
EMERGENCY MEDICINE
Gaddis GM, Graham CA. Research Abstracts of
the Seventh Mediterranean Emergency Medicine
Congress. Journal of Emergency Medicine, 2013, 46
(6):958-9.
GASTROENTEROLOGY
Chhabra R, O’Keefe JH, Patil H, O’Keefe E, Thompson
RC, Ansari S, Kennedy KF, Lee L, Helzberg JH.
Association of Coronary Artery Calcification With
Hepatic Steatosis in Asymptomatic Individuals.
Mayo Clinic Proceedings, 2013; 88: 1259-65.
MID AMERICA HEART INSTITUTE
Abdallah JS, Wang K, Magnuson EA, Spertus JA, Farkouh
ME, Fuster V, Cohen DJ. Quality of Life After PCI
vs CABG Among Patients with Diabetes and
Multivessel Coronary Artery Disease: A Randomized
Clinical Trial. JAMA 2013;310:1581-1590.
Abramsohn EM, Decker C, Garavalia B, Garavalia L,
Gosch K, Krumholz HM, Spertus JA, Lindau ST. “I’m
Not Just a Heart, I’m a Whole Person Here”: A
Qualitative Study to Improve Sexual Outcomes
in Women with Myocardial Infarction. J Am Heart
Assoc 2013;2(4):e000199.
Abdelfattah A, Allam AH, Wann S, Thompson RC, AbdelMaksoud G, Badr I, Amer HA, El-Din AE, Finch CE,
Miyamoto MI, Sutherland L, Sutherland JD, Thomas GS.
Atherosclerotic Cardiovascular Disease in Egyptian
Women. Int J Cardiol 2013 Jul 31;167(2):570-574.
Abuannadi M, Kosiborod M, Riggs L, House J,
Hamburg M, Kennedy K, Marso S. Management
of Hyperglycemia With the Administration of
Intravenous Exenatide to Patients in the Cardiac
Intensive Care Unit. Endocrine Practice 2013
Jan;10(1):81-90.
Acharjee S, Boden WE, Harztigan PM, Teo KK, Maron
DJ, Sedlin SP, Kostuk W, Spertus JA, Dada M, Chaitman
BR, Mancini GB, Weintraub WS. Low Levels of High
Density Lipoprotein Cholesterol and Increased
Risk of Cardiovascular Events in Stable Ischemic
Heart Disease Patients: A Post Hoc Analysis
from the COURAGE Trial. J Am Coll Cardiol
2013;62(20):1826-1833.
Al Badarin FJ, Spertus JA, Gosch KL, Buchanan DM,
Chan PS. Initiation of Statin Therapy After Acute
Myocardial Infarction is not Associated with
Worsening Depressive Symptoms: Insights from
the Prospective Registry Evaluating Outcomes
After Myocardial Infarctions: Events and
Recovery (PREMIER) and Translational Research
Investigating Underlying Disparities in Acute
Myocardial Infarction Patients’ Health Status
(TRIUMPH) Registries. Am Heart J 2013;166(5):
879-886.
Allen LA, Spertus JA. End points for Comparative
Effectiveness Research in Heart Failure. Heart Fail
Clin 2013;9(1):15-28.
Althouse AD, Abbott JD, Surron-Tyrrell K, Forker
AD, Lombardero MS, Buitron LV, Pena-Sing I,
Tardif JC, Mori Brooks M; for the BARI 2D Study
Group. Favorable Effects of Insulin Sensitizers
Pertinent to Peripheral Arterial Disease in Type
2 Diabetes, Results from the Bypass Angioplasty
Revascularization Investigation 2 Diabetes (BARI
2D) Trial. Diabetes Care 2013 Oct;36(10):3269-3275.
Amin AP, Bachuwar A, Reid KJ, Chhatriwalla AK,
Salisbury AC, Yeh RW, Kosiborod M, Wang TY, Alexander
KP, Cohen DJ, Spertus JA, Bach RG. Nuisance Bleeding
with Prolonged Dual Antiplatelet Therapy After
Acute Myocardial Infarction and its Impact on
Health Status. J Am Coll Cardiol 2013;61:2130-2138.
Amin AP, House JA, Safley DM, Chhatriwalla AK,
Giersiefen H, Bremer A, Hamon M, Baklanov DV,
Aluko A, Wohns D, Mathias DW, Applegate RA, Cohen
DJ, Marso SP. Costs of Transradial Percutaneous
Coronary Intervention. JACC Cardiovasc Interv 2013
Jul 12;6:827-834.
Amin AP, Whaley-Connell AT, Li S, Chen SC,
McCullough PA, Kosiborod M, on behalf of the
Kidney Early Evaluation Program Investigators. The
Synergistic Relationship Between Estimated GFR
and Microalbuminuria in Predicting Long-term
Progression to ESRD or Death in Patients with
Diabetes: Results from the Kidney Early Evaluation
Program (KEEP). Am J Kidney Dis 2013;61(suppl
2):S12-S23.
Arnold SV, Lipska KJ, Li Y, GoyalA, Maddox TM,
McGuire DK, Spertus JA, Kosiborod M. The
Reliability and Prognosis of In-Hospital Diagnosis
of Metabolic Syndrome in the Setting of Acute
Myocardial Infarction. J Am Coll Cardiol 2013 Aug
20;62(8):704-708.
2013 Research Annual Repor t // Central Office of Research Administration
31
Arnold SV, Spertus JA, Lei Y, Allen KB, Chhatriwalla
AK, Leon MB, Smith CR, Reynolds MR, Webb JG,
Svensson LG, Cohen DJ. Use of the Kansas City
Cardiomyopathy Questionnaire for Monitoring
Health Status in Patients with Aortic Stenosis. Circ
Heart Fail 2013;6(1):61-67.
Arnold SV, Spertus JA, Lei Y, Green P, Kirtane AJ,
Kapadia S, Thourani VH, Herrmann HC, Beohar N,
Zajarias A, Mach MJ, Leon MB, Cohen DJ. How to
Define a Poor Outcome After Transcatheter Aortic
Valve Replacement: Conceptual Framework and
Empirical Observations From the Placement of
Aortic Transcatheter Valve (PARTNER) Trial. Circ
Cardiovasc Qual Outcomes 2013;6(5):591-597.
Arnold SV, Spertus JA, Masoudi FA, Daugherty Smaddox
TM, Li Y, Dodson JA, Chan PS. Beyond Medication
Prescription as Performance Measures: Optimal
Secondary Prevention Medication Dosing After
Acute Myocardial Infarction. J Am Coll Cardiol
2013;61(19):1791-1801.
Baklanov D, Messenger J, Rao S. Reply to the Editor J
Am Coll Cardiol 2013 Jun 11;61(23):2394.
Baklanov DV, Kaltenbach LA, Marso SP, Subherwal
S, Feldman D, Garratt K, Curtis J, Messenger J, Rao
S. The Prevalence and Outcomes of Transradial
Percutaneous Coronary Intervention for STSegment Elevation Myocardial Infarction: Analysis
from the NCDR (2007-2011). J Am Coll Cardiol
2013;61:420-426.
Baklanov DV, Kim S, Marso SP, Subherwal S, Rao SV.
Comparison of Bivalirudin and Radial Access
Across a Spectrum of Preprocedural Risk of
Bleeding in Percutaneous Coronary Intervention:
Analysis From the National Cardiovascular
Data Registry. Circ Cardiovasc Intervention 2013
Aug;64):347-353.
Bangalore S, Pencina MJ, Kleiman NS, Cohen
DJ. Prognostic Implications of Procedural vs
Spontaneous Myocardial Infarction: Results
from the EVENT Registry. Am Heart J 2013
Dec;166(6):1027-1034.
Beller GA, Bateman TM. Provisional Use of
Myocardial Perfusion Imaging in Patients
Undergoing Exercise Stress Testing: A Worthy
Concept Fraught with Challenges. J Nucl Cardiol 2013
Oct;20(5):711-714.
Bhatti SK, DiNicolantonio JJ, Captain BK, Lavie CJ,
Tomek A, O’Keefe JH. Neutralizing the Adverse
Prognosis of Coronary Artery Calcium. Mayo Clin
Proc 2013 Aug;88(8):806-812.
32
Bhatti SK, O’Keefe JH, Hagan JC III, Lavie CJ. The Lady
Doth Protest Too Much, Methinks. MO Med 2013 JanFeb;110(1):17-20.
Bhatti SK, O’Keefe JH, Lavie CJ. LTE Reply-Of Mice
and Men: Atrial Fibrillation in Veteral Endurance
Runners. J am Coll Cardiol 2013 Sep.
Bhatti SK, O’keefe JH, Lavie CJ. Cofee and Tea: Perks
for Health and Longevity? Curr Opin Clin Nutr Metab
Care 2013 Nov;16(6):688-697.
Biffi M, Exner DV, Ramza B, Coutu B, Tomassoni G,
Kranig W, Li S, Kristiansen N, Voss F. Occurrence
of Phrenic Nerve Stimulation in Cardiac
Resynchronization Therapy Patients: The Role of
Left Ventricular Lead Type and Placement Site.
Europace 2013 Jan;15(1):77-82.
Bin Abdulhak AA, Khan AR, Tleyjeh IM, Spertus JA,
Sanders SU, Steigerwalt KE, Garbati MA, Bahmaid RA,
Wimmer AP. Safety and Efficacy of Interrupted
Dabigatran for Peri-Procedural Anticoagulation
in Catheter Ablation of Atrial Fibrillation: A
systematic Review aNd Meta-analysis. Europace 2013
15(10):1412-1420.
Bin Abdulhak AA, Tleyjeh IM, Wimmer A. Dabigatran
in the Setting of Catheter Ablation of Atrial
Fibrillation: The Road Ahead. Heart 2013.
Bishawi M, Shroyer AL, Rumsfeld JS, Spertus JA, Baltz
JH, Collins JF, Quin JA, Almassi GH, Grover FL, Hattler B.
Changes in Health-related Quality of Life in OffPump versus On-Pump Cardiac Surgery: Veterans
Affairs Randomized On/Off Bypass Trial. Ann Thorac
Surg 2013;95(6):1946-1951.
Borden WB, Spertus JA, Mushlin AI, Roe MT, McCoy
LA, Redberg RF. Antianginal Therapy Before
Percutaneous Coronary Intervention. Circ Cardiovasc
Interv 2013;6(4):436-443.
Buchanan DM, Spertus JA. A Leading Postdoctoral
Fellowship Training Program in Cardiovascular
Outcomes Research. EP Lab Digest 2013;13(11):40-42.
Bybee KA, Stevens TL. Matters of the Heart:
Cardiovascular Disease in U.S. Women. Missouri
Medicine 2013 Jan/Feb;110(1):65-70.
Cannon CP, Brindis RG, Chaitman DJ, Cohen DJ, Cross
JT, Drozda JP, Fesmire FM, Fintel DJ, Fonarow GC, Fox
KA, Gray DT, Harrington RA, Hicks KA, Hollander JE,
Krumholz H, Labarthe DR, Long JB, Mascette AM, Meyer
C, Peterson ED, Radford MJ, Roe MT, Richmann 2013
ACCF/AHA Key Data Elements and Definitions for
Measuring the Clinical Management and Outcomes
of Patients with Acute Coronary Syndromes and
2013 Research Annual Repor t // Central Office of Research Administration
Coronary Artery Disease: A Report of the American
College of Cardiology Foundation/American Heart
Association Task Force on Clinical Data Standards
(Writing Committee to Develop Acute Coronary
Syndromes and Coronary Artery Disease Clinical
Data Standards). Circ 2013;127:1053-1089 (Published
Simultaneously in J Am Coll Cardiol and Critical Pathways
in Cardiol).
Case JA, Bateman TM. Taking the Perfect Nuclear
Image: Quality Control, Acquisition, and Processing
Techniques for Cardiac SPECT, PET and Hubrid
Imaging. J Nucl Cardiol 2013 Oct;20(5):891-907.
Chamberlain AM, McNallan SM, Dunlay SM, Spertus JA,
Redfield MM, Moser DK, Kane RL, Weston SA, Roger
VL. Physican Health Status Measures Predict Allcause Mortality in Patients with Heart Failure. Circ
Heart Fail 2013;6(4):669-675.
Chan PS, Berg RA, Spertus JA, Schwamm LH, Bhatt DL,
Fonarow GC, Heidenreich PA, Nallamothu BK, Tang
F, Merchant RM. Risk-Standardizine Survival for
In-Hospital Cardiac Arrest to Facilitate Hospital
Comparisons. J Am Coll Cardiol 2013;62(7):601-609.
Chan PS, Nallamothu BK, Krumholz HM, Spertus JA, Li
Y, Hammill BG, Curtis LH. Long-Term Outcomes in
Elderly Survivors of In-Hospital Cardiac Arrest. N
Engl J Med 2013;368(11):1019-1026.
Chan PS, Rao SV, Bhatt DL, Rumsfeld JS, Gurm HS,
Nallamothu BK, Cavender MA, Kennedy K, Spertus JA.
Patient and Hospital Characteristics Associated
with Inappropriate Percutaneous Coronary
Interventions. J Am Coll Cardiol 2013;62(24):22742281.
Chan PS, Spertus JA, Nallamothu BK. Long-term
Outcomes in Elderly Survivors of Cardiac Arrest. N
Engl J Med 2013;368(25):2438-2439.
Chen LM, Nallamothu BK Spertus JA, Li Y, Chan PS.
Association Between a Hospital’s Rate of Cardiac
Arrest Incidence and Cardiac Arrest Survival. J Am
Med Assoc Intern Med 2013;173(13):1186-1195.
Chen LM, Nallamothu BK, Krumholz HM, Spertus JA,
Tang F, Chan PS. Association Between a Hospital’s
Quality Performance for In-Hospital Cardiac Arrest
and Common Medical Conditions. Circ Cardiovasc
Qual Outcomes 2013; 6(6):700-707.
Chhabra R, O’Keefe JH, Patil H, O’Keefe E, Thompson
RC, Ansari S, Kennedy KF, Lee LW, Helzberg JH.
Association of Coronary Artery Calcification with
Hepatic Steatosis in Asymptomatic Individuals.
Mayo Clin Proc 2013 Nov;88(11):1259-1265.
Chhatriwalla AK, Amin Ap, Kennedy KF, House JA,
Cohen DJ, Rao SV, Messenger JC, Marso SP; National
Cardiovascular Data Registry. Association Between
Bleeding Events and In-Hospital Mortality
Following Percutaneous Coronary Intervention.
JAMA 2013 Mar 13;309:1022-1029.
Cullom SJ, Case JA, Courter SA, McGhie AI, Bateman
TM. Regadenoson Pharmacologic Rubidium-82
PET: A Comparison of Quantitative Perfusion
and Function to Dipyridamole. J Nucl Cardiol 2013
Feb;20(1):76-83.
Dharmarajan K, Masoudi FA, Spertus JA, Li SX,
Krumholz HM. Contraindicated Initiation of
Beta-Blocker Therapy in Patients Hospitalized
for Heart Failure. J Am Med Assoc Intern Med
2013;173(16):1547-1549.
DiNicolantonio JJ, Lavie CJ, Fares H, Menezes
AR, O’Keefe JH, Bangalore S, Messerli FH. Metaanalysis of Cilostazol versus Aspirin for the
Secondary Prevention of Stroke. Am J Cardiol 2013
Oct;112(8):1230-1234.
DiNicolantonio JJ, Lavie CJ, Fares H, Menezes AR,
O’Keefe JH. Meta-analysis of Carvediolol versus
Beta-1 Selective Beta-blockers (Atenolol, Bisoprolol,
Metoprolok, and Nebivolol). Am J Cardiol 2013
Jan;111(5):765-769.
DiNicolantonio JJ, Lavie CJ, Fares H, Menezes AR,
O’Keefe JH. L-carnitine in the Secondary Prevention
of Cardiovascular Disease: Systematic Review and
Meta-analysis. Mayo Clin Proc 2013 Jun;88(6):544-551.
In Reply 2013 Aug;88(8):806-812.
DiNicolantonio JJ, Lavie CJ, O’Keefe JH. Not All
Angiotensin-converting Enzyme Inhibitors are
Equal: Focus on Ramipril and Perindopril. Postgrad
Med 2013 Jul;125(4):154-158.
DiNicolantonio JJ, McCarty MF, Lavie CJ, O’Keefe JH. Do
Omega-3 Fatty Acids Cause Prostate Cancer? MO
Med 2013 Jul-Aug;110(4):293-295.
DiNicolantonio JJ, Niazi AK, Lavie CJ, O’Keefe JH,
Ventura HO. Thiamine Supplementation for the
Treatment of Heart Failure: A Review of the
Literature. Congest Heart Fail 2013 Jul;19(4):214-222.
DiNicolantonio JJ, Niazi AK, Lavie CJ, O’Keefe JH.
Problems with the American Heart Association
Presidential Advisory Advocating Sodium
Restriction. Am J Hypertens 2013 Oct;26(10):1201-1204.
2013 Research Annual Repor t // Central Office of Research Administration
33
DiNicolantonio JJ, O’Keefe JH, Lavie CJ. Statin Wars:
The Heavyweight Match-Atorvastatin Versus
Rosuvastatin for the Treatment of Atherosclerosis,
Heart Failure, and Chronic Kidney Disease.
Postgrad Med 2013 Jan;125(1):7-16.
DiNicolantonio JJ, O’Keefe JH, Lavie CJ. LTE Reply
- The Pleiotropic Effects of Habitual Coffee
Consulption. J Am Coll Cardiol 2013 Oct.
DiNicolantonio JJ, O’Keefe, Lavie CJ. Chlorthalidone
versus Hydrochlorothiazide. Ann Intern Med 2013
Jun;158(12):920-921.
Dorian P, Burk C, Mullin CM, Bubien R, Godejohn D,
Reynolds MR, Lakkireddy DR, Wimmer AP, Bhandari
A, Spertus J. Interpreting Changes in Quality of
Life in Atrial Fibrillation: How Much Change is
Meaningful? Am Heart J 2013;166(2):381-387 e8.
Draznin B, Gilden J, Golden SH, Inzucchi SE; PRIDE
Investigators, Baldwin D, Bode BW, Boord JB, Braithwaite
SS, Cagliero E, Dungan KM, Falciglia M, Figaro MK,
Hirsch IB, Klonoff D, Korytkowski MT, Kosiborod M,
Lien LF, Magee MF, Masharani U, Maynard G, Mc
Pathways to Quality Inpatient Management of
Hyperglycemia and Diabetes: A Call to Action.
Diabetes Care 2013 Jul;36(7):1807-1814.
Ellerbeck EF, Spertus JA. Let’s Clear the Air for Casino
Patrons and Employees. Circ 2013;128(8):783-784.
El-Refai M, Peterson EL, Wells K, Swadia T, Sabbah HN,
Spertus JA, Williams LK, Lanfear DE. Comparison
of Beta-Blocker Effectiveness in Heart Failure
Patients with Preserved Ejection Fraction versus
Those with Reduced Ejection Fraction. J Card Fail
2013;19(2):73-79.
Enriquez JR, de Lemos JA, Parikh SV, Peng SA,
Spertus JA, Holper EM, Roe MT, Rohatgi A, Das
SR. Association of Chronic Lung Disease with
Treatments and Outcomes Patients with Acute
Myocardial Infarction. Am Heart J 2013;165(1):43-49.
Fatemi O, Paranilam J, Rainow A, Kennedy K, Choi J,
Curlip D, Pencina M, Berger PB, Cohen DJ, Kleiman
NS. Red Cell Distribution Width is a Predictor of
Mortality in Patients Undergoing Percutaneous
Coronary Intervention. J Thromb Thrombolysis 2013
Jan;35(1):57-64.
Feldman DN, Swaminathan RV, Kaltenbach LA, Baklanov
DV, et al. Adoption of Radial Access and Comparison
of Outcomes to Femoral Access in Percutaneous
Coronary Intervention: An Updated Report from
the National Cardiovascular Data Registry (20071012). Circ 2013;127:2295-2306.
34
Finfer S, Wernerman J, Preiser JC, Cass T, Desaive T,
Hovorka R, Joseph JI, Kosiborod M, Krinsley J, Mackenzie
I, Mesotten D, Schultz MJ, Scott MG, Slingerland R,
Van den Berghe G, Van Herpe T. Clinical Review:
Consensus Recommendations on Measurement of
Blood Glucose and Reporting Glycemic Control in
Critically Ill Adults. Crit Care 2013 Jun 13;17(3):229.
Fowler VG, Allen KB, Moreira ED, Moustafa M,
Isgro F, Boucher HW, Corey R, Carmeli Y, Betts R,
Hartzel JS, Chan I, McNeely TB, Kartsonis NA, Guris
D, Onorato MT, Smugar SS, DiNubile MJ. Effect
of an Investigational Vaccine for Preventing
Staphylococcus Aureau Infections After
Cardiothoracic Surgery: A Randomized Trial JAMA
2013;309(13):1368-1378.
Flint KM, Matlock DD, Sundareswaran KS, Lindenfeld J,
Spertus JA, Farrar DJ, Allen LA. Pre-operative Health
Status and Outcomes after Continuous-flow Left
Ventricular Assist Device Implantation. J Heart Lung
Transplant 2013;32(12):1249-1254.
Girotra S, Chan PS. Trends in Survival After
In-Hospital Cardiac Arrest. N Engl J Med
2013;368(7):680-681.
Girotra S, Spertus JA, Li Y, Berg RA, Nadkarni VM,
Chan PS. Survival Trends in Pediatric In-Hospital
Cardiac Arrests: An Analysis from Get With the
Guidelines-Resuscitation. Circ Cardiovasc Qual
Outcomes 2013;6(1):42-49.
Givertz MM, Teerlink JR, Albert NM, Westlakd Canary
CA, Collins SP, Colvin-Adams M, Ezekowitz JA, Fang JC,
Hernandez AF, Katz SD, Krishnamani R, Stough WG,
Walsh MN, Butler J, Carson PE, Dimarco JP, Hershberger
RE, Rogers JG, Spertus JA, Stevenson WG, Swe Acute
Decompensated Heart Failure: Update on New
and Emerging Evidence and Directions for Future
Research. J Card Fail 2013;19(6):371-389.
Goldberger ZD, Chan PS, Cooke CR, Hayward
RA, Krumholz HM, Nallamothu BK. Duration of
Resuscitation Efforts and Survival After InHospital Cardiac Arrest - Authors’ Reply. Lancet
2013;381(9865):447.
Gordon PC, Cohen DJ, Kleiman NS, Montgomery JA,
Semder CA, Kennedy KF, Keyes MJ, Piana RN; on behalf
of the EVENT Investigators. In-Hospital and One Year
Outcomes with Drug-eluting versus Bare Metal
Stents in Large Native coronary Arteries, a Report
from the Evaluation of Drug-eluting Stents and
Ischemic Events (EVENT) Registry. Cath Cardiovasc
Interv 2013 Oct 1;82(4):E356-364.
2013 Research Annual Repor t // Central Office of Research Administration
Gould KL, Johnson NP, Bateman TM, Beanlands RS,
Bengel FM, Bober R, Camici PG, Cerqueira MD,
Chow BJ, Di Carli MF, Dorbala S, Gewirtz H, Gropler
RJ, Kaufmann PA, Knaapen P, Knuuti J, Merhige ME,
Rentrop KP, Ruddy TD, Schelbert HR, Schindler TH,
Schwaiger Anatomic versus physiologic assessment
of coronary artery disease: role of coronary flow
reserve, fractional flow reserve, and positron
emission tomography imaging in revascularization
decision-making. J Am Coll Cardiol 2013 Oct
29;62(18):1639-1653.
Grantham JA. Coronary Stenting: A Companion
to Topol’s Textbook of Interventional Cardiology.
Mathew Price ed, 2013.
Green P, Cohen DJ, Genereux P, McAndrew T, Arnold
SV, Alu M, Beohar N, Rihal CS, Mack MJ, Kapadia S,
Dvir D, Maurer MS, Williams MR, Kodali S, Leon MB,
Kirtane AF. Relation Between Six Minute Walk Test
Performance and Outcomes After Transcatheter
Aortic Valve Implantation (from the PARTNER
Trial). Am J Cardiol 2013;112:700-706.
Harris WS, Kennedy KF, O’Keefe JH, Spertus JA. Red
Blood Cell Fatty Acid Levels Improve GRACE
Score Prediction of 2-yr Mortality in Patients
with Myocardial Infarction. Int J Cardiol 2013
Sep;168(1):53-59.
Heller GV, Beanlands R, Merlino DA, Travin MI, Calnon
DA, Dorbala S, Hendel RC, Mann A, Bateman TM, Van
Tosh A. ASNC Model Coverage Policy: Cardiac
Positron Emission Tomographic Imaging. J Nucl
Cardiol 2013 Oct;20(5):916-947.
James SK, Spertus JA. Evidence-based Treatments
for STEMI: Are We Doing Enough? Lancet
2013;382(9892):576-579.
Johnson MA, Haukoos JS, Larabee TM, Daugherty
S, Chan PS, McNally B, Sasson C. Females of
Childbearing Age have a Survival Benefit After
Out-of-Hospital Cardiac Arrest. Resuscitation
2013;84(5):639-644.
Joseph SM, Novak E, Arnold SV, Jones PG, Khattak
H, Platts AE, Davila-Roman V, Mann DLm Spertus
JA. Comparable Performance of the Kansas City
Cardiomyopathy Questionnaire in Heart Failure
Patients with Preserved and Reduced Ejection
Fraction. Circ Heart Fail 2013;6(6):1139-1146.
Kappetein AP, Head SJ, Genereux P, Piazza N, van
Mieghem NM, Blackstone EH, Brott TG, Cohen DJ,
Cutlip DE, van Es GA, Hahn RT, Kirtane AF, Krucoff
MW, Kodali S, Mack MJ, Mehran R, Rodes-Cabau J,
Vranckx P, Webb JG, Windecker S, Serruys PW, Leon
MB. Updated Standardized Endpoint Definitions
for Transcatheter Aortic Valve Implantation: The
Valve Academic Research consortium-2 Consensus
Document. J Thorac Cardiovasc Surg 2013 Jan;145(1):
6-23.
Karrowni W, Li Y, Jones PG, Cresci S, Abdallah MS,
Lanfear DE, Maddox TM, McGuire DK, Spertus JA,
Horwitz PA. Insulin Resistance is Associated with
Significant Clinical Atherosclerosis in Nondiabetic
Patients with Acute Myocardial Infarction.
Arterioscler Thromb Vasc Biol 2013;33(9):2245-2251.
Kosiborod M, Arnold SV, Spertus JA, McGuire DK, Li
Y, Yue P, Ben-Yehuda O, Katz A, Jones PG, Olmsted A,
Belardinelli L, Chaitman BR. Evaluation of Ranolazine
in Patients with Type 2 Diabetes Mellitus and
Chronic Stable Angina: Results from the TERISA
Randomized Clinical Trial (Type 2 Diabetes
Evaluation of Ranolazine in Subjects with
Chronic Stable Angina). J Am Coll Cardiol
2013;61(20);:2038-2045.
Kramer DB, Kennedy KF, Noseworthy PA, Buxton AE,
Josephson ME, Normand SL, Spertus JA, Zimetbaum
PJ, Reynolds MR, Mitchell SL. Characteristics
and Outcomes of Patients Receiving New
and Replacement Implantable CardioverterDefibrillators: Results from the NCDR. Circ
Cardiovasc Qual Outcomes 2013;6(4):488-497.
Krumholz HM, Barreto-Filho JA, Jones PG, Li Y, Spertus
JA. Decision-making Preferences Among Patients
with an Acute Myocardial Infarction. J Am Med Assoc
Intern Medf 2013;173(13):1252-1257.
Kulkarni VT, Ross JS, Wang Y, Nallamothu BK, Spertus
JA, Normand SL, Masoudi FA, Krumholz HM. Regional
Density of Cardiologists and Rates of Mortality for
Acute Myocardial Infarction and Heart Failure. Circ
Cardiovasc Qual Outcomes 2013;6(3):352-359.
Lavie CJ, DiNicolantonio JJ, Milani RV, O’Keefe JH.
Niacin Therapy Lives for Another Day -- Maybe? J
Am Coll Cardiol 2013 May;61(21):2197-2198.
Lavie CJ, DiNicolantonio JJ, Milani RV, O’Keefe JH.
Vitamin D and Cardiovascular Health. Circ 2013
Nov;128(22):2404-2406.
Lavie CJ, DiNicolantonio JJ, O’Keefe JH, Milani RV.
Vitamin D Status, Left Ventricular Geometric
Abnormalities and Cardiovascular Disease. J Intern
Med 2013 Mar;273(3):246-248.
2013 Research Annual Repor t // Central Office of Research Administration
35
Lavie CJ, DiNicolantonio JJ, O’Keefe JH, Ventura HO.
Aldosterone Antagonists: Evidence-based yet
Underutilized Effective Heart Failure Therapy.
Congest Heart Fail 2013 May;19(3):105-106.
Leifheit-Limson EC, Spertus JA, Reid KJ, Jones SB,
Vaccarino V, Krumholz HM, Lichtman JH. Prevalence
of Traditional Cardiac Risk Factors and Secondary
Prevention Among Patients Hospitalized for Acute
Myocardial Infarction (AMI): Variation by Age,
Sex, and Race. J Womens Health (Larchmt)
2013;22(8):659-666.
Lyons MR, Peterson LR, McGill JB< Herrero P,
Coggan AR, Saeed IM, Recklein C, Schechtman
KB, Gropler RJ. Impact of Sex on the Heart’s
Metabolic and Functional Responses to Diabetic
Therapies. Am J Physiol Heart Circ Physiol 2013
Dec;305(11):H1584-1591.
Magnuson EA, Farkouh ME, Fuster V, Wang K, Vilain
K, Li H, Appelwick J, Muratov V, Sleeper LA, Boineau
R, Abdallah M, Cohen DJ. Cost-Effectiveness of
Percutaneous Coronary Intervention with Drug
Eluting Stents versus Bypass Surgery for Patients
with Diabetes and Multivessel Coronary Artery
Disease: Results from the FREEDOM Trial. Circ
2013;127:820-831.
Main ML, Grayburn PA, Lang RM, Goldman JH,
Gibson CM, Sherwin P, Demaria AN. Effect of Optison
on Pulmonary Artery Systolic Pressure and
Pulmonary Vascular Resistance. Am J Cardiol 2013
Nov 15;112(10):1657-1661.
Mancini GB, Hartigan PM, Bates ER, Chaitman BR,
Sedlis SP, Maron DJ, Kostuk WJ, Spertus JA, Teo KK,
Dada M, Knudtson M, Berman DS, Booth DC, Boden
WE, Weintraub WS. Prognostic Importance of
Coronary Anatomy and Left Ventricular Ejection
Fraction Despite Optimal Therapy: Assessment of
Residual Risk in the Clinical Outcomes Utilizing
Revascularization and Aggressive DruG Evaluation
Trial. Am Heart J 2013;166(3):481-487.
Marso S, Poulter N, Nissen S, Nauck M, Zinman B,
Daniels G, Pocock S, Steinberg W, Bergenstal R, Mann
J, Steen Ravn L, Brown FK, Moses A, Buse J. Design
of the Liraglutide Effect and Action in Diabetes:
Evaluation of Cardiovascular Outcome Results
(LEADER) Trial - On Behalf of the LEADER Trial
Investigators. Am Heart J 2013 Nov;166(5):823-830.
36
Martin SS, Gosch K, Kulkarni KR, Spertus JA, Mathews
R, Ho PM, Maddox TM, Newby LK, Alexander KP, Wang
TY. Modifiable Factors Associated with Failure to
Attain Low-density Lipoprotein Cholesterol Goal
at 6 months after Acute Myocardial Infarction. Am
Heart J 2013;165(1):26-33 e3.
Masoudi FA, Ponirakis A, Yeh RW, Maddox TM, Beachy
J, Casale PN, Curtis JP, De Lemos J, Fonarow G,
Yheidenreich P, Koutras C, Kremers M, Messenger J,
Moussa I, Oetgen WJ, Roe MT, Rosenfield K, Shields
TS, Spertus JA, Wei J, White C, Young CH, Rumsfeld
JS. Cardiovascular Care Facts: A Report from the
National Cardiovascular Data Registry - 2011. J am
Coll Cardiol 2013;62(21):1931-1947.
Mathur S, Heller GV, Bateman TM, Ruffin R, Yekta
A, Katten D, Alluri N, Ahlberg AW. Clinical value of
Stress-Only Tc-99m SPECT Imaging: Importance
of Attenuation Correction. J Nucl Cardiol 2013
Feb;20(1):27-37.
McCrary J, Wann LS, Thompson RC. PET Imaging with
FDG to Guide Revascularization in Heart Failure
Patients. Egypt Heart J 2013 June;65(2):123-129.
Mehran R, Baber U, Steg PG, Ariti C, Weisz G,
Witzenbichler B, Henry Td, Kini AS, Stuckey T, Cohen DJ,
Berger PB, Iakovou I, Dangas G, Waksman R, Antoniucci
D, Sartori S, Krucoff MW, Hermiller JB, Shawl F, Gibson
CM, Dhieffo A, Alu M, Moliterno DJ, Colomb Cessation
of Dual Antiplatelet Treatment and Cardiac Events
After Percutaneous Coronary Intervention (PARIS):
2 Year Results from a Prospective Observational
Study. Lancet 2013 Nov 23;382(9906):1714-1722.
Menezes AR, Lavie CJ, DiNicolantonia JJ, O’Keefe JH,
Morin DP, Khatib S, Milani RV. Atrial Fibrillation in
the 21st Century: A Current Understanding of Risk
Factors and Primary Prevention Strategies. Mayo
Clin Proc 2013 Apr;88(4):349-409.
Mercado N, Cohen DJ, Spertus JA, Chan PS, House
J, Kennedy K, Brindis RG, White CJ, Rosenfield KA,
Marso SP. Carotid Artery Stenting of a Contralateral
Occlusion and In-Hospital Outcomes: Results From
the CARE (Carotid Artery Revascularization and
Endarterectomy) Registry. JACC Cardiovasc Interv
2013;6(1):59-64.
Merchant FM, Zheng H, Bigger T, Steinman R, Ikeda
T, Pedretti RF, Salerno-Uriarte JA, Klersy C, Chan PS,
Bartone C, Hohnloser SH, Ruskin JN, Armoundas AA.
A Combined Anatomic and Electrophysiologic
Substrate Based Approach for Sudden
Cardiac Death Risk Stratification. Am Heart J
2013;166(4):744-752.
2013 Research Annual Repor t // Central Office of Research Administration
Miller AL, Gosch K, Daugherty SL, Rathore S, Peterson
PN, Peterson ED, Ho PM, Chan PS, Lanfear DE,
Spertus JA, Wang TY. Failure to Reassess Ejection
Fraction After Acute Myocardial Infarction in
Potential Implantable Cardioverter/Defibrillator
Candidates: Insights from the Translational
Research Investigating Underlying Disparities in
Acute Myocardial Infarction Patients’ Health Status
(TRIUMPH) Registry. Am Heart J 2013;166(4):737-743.
Miller AL, Gosch K, Daugherty SL, Rathore S, Peterson
PN, Peterson ED, Ho PM, Chan PS, Lanfear DE,
Spertus JA, Wang TY. Failure to Reassess Ejection
Fraction After Acute Myocardial Infarction in
Potential Implantable Cardioverter/Defibrillator
Candidates: Insights from the Translational
Research Investigating Underlying Disparities in
Acute Myocardial Infarction Patients’ Health Status
(TRIUMPH) Registry. Am Heart J 2013;166(4):737-743.
Moe T, Kao A, Magalski A. Recurrent Hemoptysis in a
30-Year Old Female with Epstein’s Anomaly and a
Prior History Epicardial ICD Patches: Status Post
Orthotopic Heart Transplant. Congenital Cardiology
Today 2013 Aug;11(8):1-4.
Moraska AR, Chamberlain AM, Shah ND, Vickers
KS, Rummans TA, Dunlay SM, Spertus JA, Weston SA,
McNallan SM, Redfield MM, Roger VL. Depression,
Healthcare Utilization, and Death in Heart Failure: A
Community Study. Circ Heart Fail 2013;6(3):387-394.
Nallamothu BK, Spertus JA, Lansky AJ, Cohen DJ,
Jones PG, Kuresh F, Dehmer GJ, Drozda JP, Walsh MN,
Brush JE, Koenig GC, Waites TF, Gantt DS, Kichura
G, Chazal RA, O’Brien PK, Valentine CM, Rumsfeld
JS, Reiber JHC, Elmore JG, Krumholz RA, Weaver WD,
Krumh Comparison of Clinical Interpretation and
Quantitative Coronary Angiography in Patients
Undergoing Percutaneous Coronary Intervention in
Contemporary Practice: The Assessing Angiography
(A2) Project. Circ 2013;127:1793-1800.
Nallamothu BK, Spertus JA, Lansky AJ, Cohen DJ, Jones
PG, Kureshi F, Dehmer GJ Jr, Walsh MN, Brush JE Jr,
Koenig GC, Waites TF, Gantt DS, Kichura G, Chazal
RA, O’Brien PK, Valentine CM, Rumsfeld JS, Reiber
JH, Elmore JG, Krumholz RA, Weaver WD, Krumholz
H Comparison of Clinical Interpretation with
Visual Assessment and Quantitative Coronary
Angiography in Patients Undergoing Percutaneous
Coronary Intervention in Contemporary Practice:
The Assessing Angiography (A2) Project. Circ
2013;127(17):1793-1800.
Niazi AK, Dinicolantonio JJ, Lavie CJ, O’Keefe JH,
Meier P, Bangalore S. Triple versus Dual Antiplatelet
Therapy in Acute coronary Syndromes: Adding
Cilostazol to Aspirin and Clopidogrel? Cardiology
2013 Oct 1;126(4):233-243.
O’Keefe JH Jr, O’Keefe J. Let Me Tell You a Story.
Andrew McMeel Universal, January 2013, Book, Kansas
City, MO.
O’Keefe JH, Bhatti SK, Patil HR, DiNicolantonio JJ, Lucan
SC, Lavie CJ. Effects of Habitual Coffee Consumption
on Cardiometabolic Disease, Cardiovascular
Hearth, and All-cause Mortality. J Am Coll Cardiol
2013 Sep;62(12):1043-1051.
O’Keefe JH, Lavie CJ. Run for Your Life…At a
Comfortable Speed and Not Too Far. Heart 2013
Apr;99(8):516-519.
O’Keefe JH, Schnohr P, Lavie CJ. The Dose of
Running that Best Confers Longevity. Heart 2013
Apr;99(8):588-590.
Osnabrugge RL, Kappetein AP, Reynolds MR,
Cohen DJ. Cost-Effectiveness of Transcatheter
Valvular Interventions: Economic Challenges.
EuroIntervention 2013 Sep 10;9Suppl:S48-54.
Parashar S, Kella D, Reid KJ, Spertus JA, Tang F,
Langberg J, Vaccarino V, Kontos MC, Lopes RD, Lloyd
MS. New-Onset Atrial Fibrillation After Acute
Myocardial Infarction and Its Relation to Admission
Biomarkers (from the TRIUMPH Registry). Am J
Cardiol 2013;112(9):1390-1395.
Parker JM, Weller MW, Feinstein LM, Adams RJ, Main
ML, Grayburn PA, Cosgrove DO, Goldberg BA, Darge
K, Nihoyannopoulos P, Wilson S, Monaghan M, Piscaglia
F, Fowlkes B, Mathias W, Moriyasu F, Chammas MC,
Greenbaum L, Feinstein SB. Safety of Ultrasound
Contrast in Patients with Known or Suspected Cardiac
Shunts. Am J Cardiol 2013 Oct 1;112(7):1039-1045.
Payvar S, Spertus JA, Miller AB, Casscells SW, Pang
PS, Zannad F, Swedberg K, Maggioni AP, Reid
KJ, Gheorghiade M. Association of Low Body
Temperature and Poor Outcomes in Patients
Admitted with Worsening Heart Failure: A Substudy
of the Efficacy of Vasopressin Antagonism in Heart
Failure Outcome Study with Tolvaptan (EVEREST)
Trial. Eur J Heart Fail 2013;15(12):1382-1389.
2013 Research Annual Repor t // Central Office of Research Administration
37
Peterson PN, Chan PS, Spertus JA, Tang F, Jones PG,
Ezekowitz JA, Allen LA, Masoudi FA, Maddox TM.
Practice-level Variation in Use of Recommended
Medications Among Outpatients with Heart Failure:
Insights from the NCDR PINNACLE Program. Circ
Heart Fail 2013;Nov 1;6(6):1132-1138.
Safley D, Amin A, House J, Baklanov D, Mills J, Giersiefen
H, Bremer A, Marso S. Comparison of Costs Between
Transradial and Transfemoral Percutaneous
Coronary Intervention: A Cohort Analysis from the
Nationwide Premier Perspective Hospital Database.
Am Heart J 2013 Mar;165(1):303-306.
Peterson PN, Chan PS, Spertus JA, Tang F, Jones PG,
Ezekowitz JA, Allen LA, Masoudi FA, Maddox TM.
Practice-level Variation in Use of Recommended
Medications Among Outpatients with Heart Failure:
Insights from the NCDR PINNACLE Program. Circ
Heart Fail 2013;6(6):1132-1138.
Salisbury AC, Wang K, Cohen DJ, Li Y, Jones PG, Spertus
JA. Selecting Antiplatelet Therapy at the time of
Percutaneous Intervention for an Acute Coronary
Syndrome: Weighing the Benefits and Risks of
Prasugrel versus Clopidogrel. Circ Cardiovasc Qual
Outcomes 2013;6(1):27-34
Rajamani K, Kennedy KF, Ruggiero NJ, Rosenfield
K, Spertus J, Chaturvedi S. Outcomes of Carotid
Endarterectomy in the Elderly: Report From the
National Cardiovascular Data Registry. Stroke
2013;44(4):1172-1174.
Sasson C, Meischke H, Abella BS, Berg RA, Bobrow BJ,
Chan PS, Root ED, Heisler M, Levy JH, Link M, Masoudi
F, Ong M, Sayre MR, Rumsfeld JS, Rea TD. Increasing
Cardiopulmonary Resuscitation Provision in
Communities with Low Bystander Cardiopulmonary
Resuscitation Rates: A Science Advisory from
the American Heart Association for Healthcare
Providers, Policymakers, Public Health Departments
and Community Leaders. Circ 2013;127(12):13421350.
Rao SC, Chhatriwalla AK, Kennedy KF, Decker CJ, Gialde
E, Spertus JA, Marso SP. Pre-procedural Estimate of
Individualized Bleeding Risk Impacts Physicians’
Utilization of Bivalirudin During Percutaneous
Coronary Intervention. J Am Coll Cardiol
2013;61(18):1847-1852.
Rao SV McCoy LA, Spertus JA, Krone RJ, Singh M,
Firzgerald S, Peterson ED. An Updated Bleeding Model
to Predict the Risk of Post-Procedure Bleeding
Among Patients Undergoing Percutaneous Coronary
Intervention: A Report Using an Expanded Bleeding
Definition from the National Cardiovascular Data
Registry Cath PCI Registry. JACC Cardiovasc Interv
2013;6(9):897-904.
Rasalingam R, Saeed IM. Recent Advances in Cardiac
Stress Testing. J Insur Med 2013;43(4):227-232.
Reynolds MR, Cohen DJ. The Cost-Effectiveness of
TAVR for Non-Surgical Candidates: Revisionist
History or the Final Word? Circ Cardiovasc Qual
Outcomes 2013;6:376-378.
Rumsfeld JS, Alexander KP, Goff DC Jr, Graham MM, Ho
PM, Masoudi FA, Moser DK, Roger VL, Slaughter MS,
Smolderen KG, Spertus JA, Sullivan MD, Treat-Jacogson
D, Zerwic JJ. Cardiovascular Health: The Importance
of Measuring Patient-reported Health Status: A
Scientific Statement from the American Heart
Association. Circ 2013;127(22):2233-2249.
38
Sedlis SP, Jurkovitz CT, Hartigan PM, Kolm P, Goldfarb
DS, Lorin JD, Dada M, Maron DJ, Spertus JA, Mancini
GB, Teo KK, Boden WE, Weintraub WS. Health Status
and Quality of Life in Patients with Stable Coronary
Artery Disease and Chronic Kidney Disease Treated
with Optimal Medical Therapy or Percutaneous
Coronary Intervention (Post Hoc Findings from the
COURAGE Trial). Am J Cardiol 2013;112(11):17031708.
Seymour CW, Cooke CR, Heckbert SR, Copass MK, Yealy
DM, Spertus JA, Rea TD. Prehospital Systolic Blood
Pressure Thresholds: A Community-based Outcomes
Study. Acad Emerg Med 2013;20(6):597-604.
Shamin S, Al Badarin FJ, DiNicolantonio JJ, Lavie CJ,
O’Keefe JH. Red Yeast Rice for Dyslipidemia. MO Med
2013 Jul-Aug;110(4):349-354.
Shore S, Borgerding JA, Gylys-Colwell I, McDermott K,
Michael Ho P, Tillquist MN, Lowy E, McGuire DK, Stolker
JM, Arnold SV, Kosiborod M, Maddox TM. Association
Between Admission Hyperglycemia During
Hospitalization for Acute Myocardial Infarction and
Subsequent Diabetes: Insights from the Veterans
Administration Cardiac Care Follow-up Clinical
Study. Diabetes Care 2013 Oct 2.
2013 Research Annual Repor t // Central Office of Research Administration
Smolderen KG, Spertus JA, Tang F, Oetgen W, Borden
WB, Ting HH, Chan PS. Treatment Differences
by Health Insurance Among Outpatients with
Coronary Artery Disease: Insights from the
National Cardiovascular Data Registry ®. J Am Coll
Cardiol 2013;61(10):1069-1075.
Sood N, Al Bararin F, Parker M, Pullatt R, Jacobson AF,
Bateman TM, Heller GV. Resting Perfusion MPI-SPECT
Combined with Cardiac 123I-mIBGG Sympathetic
Innervation Imaging Improves Prediction of
Arrhythmic Events in Non-Ischemic Cardiomyopathy
Patients: Sub-Study from the ADMIRE-HF Trial. J
Nucl Cardiol 2013 Oct;20(5):813-820.
Spertus JA, Maron DJ, Cohen DJ, Kolm P, Hartigan P,
Aslan M, Weintraub WS, Berman DS, O’Rourke RA, Teo
K, Shaw LJ, Sedlis S, Knudtson M, Kostuk W, Frutkin
AD, Dada M, Boden WE, Mancini GBJ. Frequency,
Predictors, and Consequences of Crossing
Over to Revascularization within 12 months of
Randomization to Optimal Medical Therapy in the
Clinical Outcomes Utilizing Revascularization and
Aggressive Drug Evaluation (COURAGE) Trial.
Circ Cardiovasc Qual Outcomes 2013;6(4):409-418.
Stevens TL. Historical Study: Benjamin D.
McCallister, MD, MACC (1932-2012). Am J Cardiol
2013 Apr 15;111(8):1230.
Subherwal S, Patel MR, Tang F, Smolderen KG,
Jones WS, Tsai TT, Ting HH, Bhatt DL, Spertus JA,
Chan PS. Socioeconomic Disparities in Use of
Cardioprotective Medications Among Patients
with Peripheral Artery Disease - An Analysis
of the American College of Cardiology’s NCDR
PINNACLE Registry ®. J Am Coll Cardiol
2013;62(1):51-57.
Swift DL, Lavie CJ, Johannsen NM, Arena R, Earnest CP,
O’Keefe JH, Milani RV, Blair SN, Church TS. Physical
Activity, Cardiorespiratory Fitness, and Exercise
Training in Primary and Secondary Coronary
Prevention. Circ 2013 Jan;77(2):281-292.
Thomas GS, Voros S, McPherson JA, Lansky AJ, Winn
ME, Bateman TM, Elashoff MR, Lieu HD, Johnson
AM, Daniels SE, Ladapo JA, Phelps CE, Douglas PS,
Rosenberg S. A Blood-Based Gene Expression Test
for Obstructive Coronary Artery Disease Tested
in Symptomatic Nondiabetic Patients Referred
for Myocardial Perfusion Imaging the COMPASS
Study. Circ Cardiovasc Genetics 2013 Apr;6(2):154-162.
Thompson RC, Allam AH, Lombardi GP, Wann LS,
Sutherland ML, Sutherland JD, Soliman MA, Frohlich B,
Mininberg DT, Monge JM, Vallodolid CM, Cox SL, Abd
el-Maksoud G, Badr I, Miyamoto MI, el-Halim Nur elDin A, Narula J, Finch Ce, Thomas GS. Atherosclerosis
Across 4000 Years Of Human History: The Horus
Study Of Four Ancient Populations. Lancet 2013 Apr
6;381(9873):1211-1222.
Thompson RC, Allam AH, Wann LS, Finch CE, Thomas
GS. Atherosclerosis in Ancient Populations Authors’ Reply. Lancet 2013 Jul 2;382(9887):123-124.
Thompson RC, Patil H, Thompson EC, Thomas GS,
Al-Amoodi M, Kennedy KF, Bybee KA, McGhie I,
O’Keefe JH Jr, Oakes L, Bateman TM. Regadenoson
Pharmacologic Stress for Myocardial Perfusion
Imaging: A Three-Way Comparison Between
Regadenoson Administered at Peak Exercise,
During Walk Recovery, or No-Exercise. J Nucl
Cardiol 2013 Apr;20(2):214-221.
Van Geldorp MW, Heuvelman HJ, Kappetein AP,
Busschbach JJ, Cohen DJ, Takkenberg JJ, Bogers AJ.
Quality of Life Among Patients with Severe Aortic
Stenosis. Neth Heart J 2013;35:21-27.
Vedantham S, Goldhaber SZ, Kahn SR, Julian J,
Magnuson E, Jaff MR, Murphy TP, Cohen DJ, Comerota
AF, Gornik HL, Razavi MK, Lewis L, Kearon C.
Rationale and Design of the ATTRACT Study:
A Multicenter Randomized Trial to Evaluate
Pharmacomechanical Catheter-Directed
Thrombolysis for the Prevention of Postthrombotic
Syndrome in Patients with Proximal Deep Vein
Thrombosis. Am Heart J 2013;165:523-553.
Venkitachalam L, McGuyire DK, Gosch K, Lipska K,
Inzucchi SE, Lind M, Goyal A, Spertus JA, Masoudi
FA, Jones PG, Kosiborod M. Temporal Trends and
Hospital Variation in the Management of Severe
Hyperglycemia Among Patients with Acute
Myocardial Infarction in the United States. Am
Heart J 2013 Aug;166(2):315-324.
Waksman R, Legutko J, Singh J, Orlando Q, Marso S,
Scholoss T, Tugaoen J, Devries J, Palmer N, Haude M,
Swymelar S, Torguson R. Fractional Flow Reserve
and Intravascular Ultrasound RelationShip Study:
The FIRST Study. J am Coll Cardiol 2013 Mar
5;61(0):917-923.
2013 Research Annual Repor t // Central Office of Research Administration
39
Wasfy JH, Rosenfield K, Zelevinsky K, Sakhuja R, Lovett
A, Spertus JA, Wimmer NJ, Mauri L, Normand SL, Yeh
RW. A Prediction Model to Identify Patients at High
Risk for 30-day Readmission After Percutaneous
Coronary Intervention. Circ Cardiovasc Qual
Outcomes 2013;6(4):429-435.
Wetmore JB, Ellerbeck EF, Mahnken JD, Phadnis M,
Rigler SK, Mukhopadhyay P, Spertus JA, Zhou X, Hou Q,
Shireman TI. Atrial Fibrillation and Risk of Stroke in
Dialysis Patients. Ann Epidemiol 2013;23(3):112-118.
Wetmore JB, Ellerbeck EF, Mahnken JD, Phadnis
MA, Rigler SK, Spertus JA, Zhou X, Mukhopadhyay
P, Shireman TI. Stroke and the “Stroke Belt” in
Dialysis: Contribution of Patient Characteristics to
Ischemic Stroke Rate and Its Geographic Variation.
J Am Soc Nephrol 2013;24(12):2053-2061.
Whaley-Connell AT, Kurella Tamura M, Jurkovitz CT,
Kosiborod M, McCullough PA. Advances in CKD
Detection and Determination of Prognosis:
Executive Summary of the National Kidney
Foundation Kidney Early Evaluation Program
(KEEP) 2012 Annual Data Report Executive
Summary. Am J Kidney Dis 2013;61(suppl 2):S1-S3.
Williams JB, Alexander KP, Morin JF, Langlois Y, Noiseux
N, Perrault LP, Smolderen K, Arnold SV, Eisenberg MJ,
Pilote L, Monette J, Bergman H, Smith PK, Afilalo J.
Preoperative Anxiety as a Predictor of Mortality
and Major Morbidity in Patients aged >70 Years
Undergoing Cardiac Surgery. Am J Cardiol 2013 Jan
1;111(1):137-142.
NEUROSCIENCE INSTITUTE
Burkart J, Day JS, Henderson K, Borsa J. Efficacy of
peripheral interventional radiologists performing
endovascular stroke therapy guided by CT perfusion
triage of patients. J VascIntervRadiol 2013;24:1267–1272.
40
Stroke Systems of Care: A Policy Statement From
the American Heart Association/American Stroke
Association. Stroke. 2013 Aug 29.
Jauch EC, Saver JL, Adams HP, Bruno A, Connors JJ,
Demaerschalk BM, Khatri P, McMullan PW, Qureshi AI,
Rosenfield K, Scott PA, Summers D, Wang DZ, Wintermark
M and Yonas H. Guidelines for the Early Management
of Patients With Acute Ischemic Stroke : A Guideline
for Healthcare Professionals From the American
Heart Association/American Stroke Association.
Stroke. 2013 Mar;44(3):870-947.
Rymer MM, Armstrong EP, Meredith NR, Pham SV,
Thorpe K, Kruzikas DT. Analysis of the costs and
payments of a coordinated stroke center and regional
stroke network. Stroke. 2013 Aug;44(8):2254-9.
Rymer MM, Armstrong EP, Walker G, Pham S, Kruzikas D.
Analysis of a coordinated stroke center and regional
stroke network on access to acute therapy and
clinical outcomes. Stroke. 2013 Jan;44(1):132-7.
Zaidat OO, Castonguay AC, Gupta R, Sun CH, Martin C,
Holloway WE, Mueller-Kronast N, English JD, Linfante I,
Dabus G, Malisch TW, Marden FA, Bozorgchami H, Xavier
A, Rai AT, Froehler MT, Badruddin A, Nguyen TN, Taqi
MA, Abraham MG, Janardhan V, Shaltoni H, Novakovic
R, Yoo AJ, Abou-Chebl A, Chen PR, Britz GW, Kaushal
R, Nanda A, Issa MA, Nogueira RG. North American
Solitaire Stent Retriever Acute Stroke registry: postmarketing revascularization and clinical outcome
results. J Neurointerv Surg. 2013 Sep 23.
NURSING
Abramsohn EM, Decker C, Garavalia B, Garavalia L,
Gosch K, Krumholz HM, Spertus JA, Lindau ST .I’m
Not Just a Heart, I’m a Whole Person Here: A
Qualitative Study to Improve Sexual Outcomes in
Women with Myocardial Infarction. Journal of the
American Heart Association, 2013; July 24; 2(4):e000199.
Donovan NJ, Daniels SK, Edmiaston J, Weinhardt J,
Summers D, and Mitchell PH, on behalf of the American
Heart Association Council on Cardiovascular Nursing and
Stroke Council. Dysphagia Screening: State of the Art
Invitational Conference Proceeding From the Stateof-the-Art Nursing Symposium, International Stroke
Conference 2012. Stroke. 2013 Apr;44(4):e24-31.
Rao SC, Chhatriwalla AK, Kennedy KF, Decker C, Gialde
E, Spertus JA, Marso, SP. Pre-Procedural Estimate of
Individualized Bleeding Risk Impacts Physicians’
Utilization of Bivalirudin during Percutaneous
Coronary Intervention. Journal of the American
College of Cardiology, 2013; 61(18): 1847-1852.
Higashida R, Alberts MJ, Alexander DN, Crocco TJ,
Demaerschalk BM, Derdeyn CP, Goldstein LB, Jauch EC,
Mayer SA, Meltzer NM, Peterson ED, Rosenwasser RH,
Saver JL, Schwamm L, Summers D, Wechsler L, Wood JP;
on behalf of the American Heart Association Advocacy
Coordinating Committee. Interactions Within
Blais D, Zukkoor S, Hayes C, Pickworth K, Porter K,
Firstenberg M. Bleeding Outcomes Associated with
Coronary Artery Bypass Surgery and Recent
Clopidogrel Exposure. The Heart Surgery Forum.
2013;16(2):e70-e77.
PHARMACY
2013 Research Annual Repor t // Central Office of Research Administration
Shewmaker J. Quetiapine Induced Leukopenia and
Neutropenia in an Intensive Care Unit Patient with
Delirium and a Review of the Literature. J Pharm
Technol 2013;29:9-12.
Prescott-Focht JA, Martinez-Jimenez S, Hurwitz LM,
Hoang JK, Christensen JD, Ghoshhajra BB, Abbara S.
Ascending Thoracic Aorta: Postoperative Imaging
Evaluation. Radiographics 2013 Jan; 33(1):73-85.
RADIOLOGY
Reddy GP, Steiner R, Walker CM. Cardiac Imaging.
Case Review Series, 2nd edition. Elsevier. 2013.
Abbara S, Walker CM, et al. Diagnostic Imaging:
Cardiovascular, 2nd edition. Amirsys. 2013. Primary
author of 17 book chapters (126 pages)
Benson REC, Rosado de Christenson ML, MartínezJiménez S, Kunin JR, Pettavel PP. Spectrum of
Pulmonary Neuroendocrine Proliferations.
RadioGraphics 2013; 33:1631-1649.
Benson RE, Rosado-de-Christenson ML, MartinezJimenez S, Kunin JR, Watson K, Pettavel PP. Spectrum
of Thoracic Neuroendocrine Proliferations and
Neoplasms: Carcinoid, Carcinoid Tumorlets,
DIPNECH, & Carcinoid Syndrome. RadioGraphics
2013; 33:1631-1649.
Retrepo CS, Carrillo J, Rosado de Christenson ML, Ojeda
Leon P, Rivera AL, Koss MN. Lymphoproliferative
Lung Disorders: A Radiologic-Pathologic Overview.
Part II: Neoplastic Disorders. Semin Ultrasound CT
MRI 2013; 34: 535-549
Saettele M, Morelli J, Chesis P, Wible BC. Use of a Trellis
Device for Endovascular Treatment of Venous
Thrombosis Involving a Duplicated Inferior Vena
Cava. Cardiovasc Intervent Radiol. 2013 February. PMID:
23370490.
Shinn-Huey SS, Walker CM, Chung JH. Ischemic Late
Gadolinium Enhancement. J Thorac Imaging. 2013
Sep;28(5):W67-8.
Benson REC, Rosado de Christenson ML, Pettavel
PP. Author’s Response to Invited Commentary.
Radiographics 2013; 33: 1651.
Ternes T, Trump M, Rosado de Christenson ML, Howell
G, Stewart J. Spontaneous Middle Lobe Torsion.
Radiology Case Reports (Online) 2013; 8 (1): 812.
Bhatt MY, Martínez-Jiménez S, Rosado de Christenson
ML, Watson KR, Walker CM, Kunin JR. Imaging
Manifestations of Mediastinal Fat Necrosis. Case
Reports in Radiology 2013; Article ID 323579.
Walker CM, Saldana DA, Gladish GW, Dicks DL, Kicska
G, Mitsumori LM, Reddy GP. Cardiac Complications
of Oncologic Therapy. Radiographics 2013 Oct;33(6):
1801-1815.
Burkart DJ, Day JS, Henderson K, Borsa JJ. Efficacy of
Peripheral Interventional Radiologists Performing
Endovascular Stroke Therapy Guided by CT
Perfusion Triage of Patients. J Vasc Interv Radiol 2013
Sept;24(9):1267-1272.
Walker CM, Reddy GP, Steiner R. Radiology of the Heart.
In: Essential Cardiology Principles and Practice.
Edited by Rosendorff C. Third Edition. Springer 2013.
Carrillo J, Restrepo CS, Rosado de Christenson ML, Ojeda
Leon P, Rivera AL, Koss MN. Lymphoproliferative
Lung Disorders: A Radiologic-Pathologic Overview.
Part I: Reactive Disorders. Semin Ultrasound CT MRI
2013; 34: 525-534.
Chhabra R, O’Keefe JH, Patil H, O’Keefe E, Thompson
RC, Ansari S, Kennedy KF, Lee L, Helzberg JH. Hepatic
Steatosis Independently Predicts The Presence Of
Coronary Artery Calcification In Asymptomatic
Individuals. Mayo Clinic Proceedings 2013.
Jeffrey BR, Manaster BJ, Osborn AG, Rosado de
Christenson ML. Diagnostic Imaging Emergency,
Second Edition. Salt Lake City. Amirsys, 2013
Martínez-Jiménez S, Heyneman LE. Imaging of the
Postoperative Thoracic Aorta. In: Problem Solving
in Cardiovascular Imaging. Editors Suhny Abbara MD
and Sanjeeva Kalva MD. Elsevier Saunders. 2013.
Ngo A, Walker CM, Chung JH, et al. Tumors and
Tumor-Like Conditions of the Large Airways. Am J
Roentgenol. 2013 Aug;201(2):301-13.
Walker CM, Reddy GP. Valves: Magnetic Resonance
Imaging. In: Problem Solving in Cardiovascular
Imaging. Edited by Abbara S and Kalva SP. Elsevier 2013.
Walker CM, Chung JH, Abbott GF, Shepard JO. Reply.
Am J Roentgenol 2013 May; 200(5):W541.
Walker CM, Reddy GP, Chung JH. Non-Ischemic
Delayed Enhancement. Signs in Cardiopulmonary
Imaging. J Thorac Imaging. 2013 Mar;28(2):W27.
SURGERY
Friedell ML, Lambe, B, Bedway, J. Percutaneous
Femoral Vein Access for Inferior Vena Cava
Filter Placement Does Not Cause Insertion Site
Thrombosis. Annals of Vascular Surgery, 2013 Nov;
27(8): 1169-72.
Friedell ML. Surgical Resident Allocation: An Art
or a Mathematical Formula? Commentary on:
An Analytic Decision Support Tool for Resident
Allocation. JSE 2013; 70(1): 36.
WOMEN AND CHILDREN
Maulik, D. Series on Maternal Fetal Medicine, Informa
CRC Press, 2007-current.
2013 Research Annual Repor t // Central Office of Research Administration
41
2013 Abstracts & Presentations
ANESTHESIOLOGY
Diaz JA, Fibuch EE, Mao LM, Wang JQ. Amphetamine
Increases Phosphorylation of the Glua1 APMA
Receptors in Synaptic and Extrasynaptic
Membranes of the Rat Forebrain. MARC. 4-27-13.
Kansas City, MO.
Edwards MC, Yue B, Mao LM, Fibuch EE, Wang JQ.
A Time-Dependent Increase In AMPA Receptor
Glua1 Phosphorylation in Confined Synaptic and
Extrasynaptic Locations in the Rat Striatum and
Prefrontal Cortex. MARC. 4-27-13. Kansas City, MO.
Montalbano AJ, Theisen CS, Fibuch EE, Seidler NW.
Isoflurane Enhances The Moonlighting Activity
Of GAPDH: Implications for Gabaa Receptor
Trafficking. MARC. 4-27-13. Kansas City, MO.
Reusch JM, Fibuch EE, Mao LM, Wang JQ. Effects of
Amphetamine on ERK Phosphorylation in Synaptic
and Extrasynaptic Compartments of Rat Striatal
and Cortical Neurons. MARC. 4-27-13. Kansas City,
MO.
Roberts LA, Fibuch EE, Seidler NW. Isoflurane’s
Effect on Protein Dynamics: Implications on the
Mechanics of Anesthesia. MARC. 4-27-13, Kansas
City, MO.
Wang CM, Jiang Q, Fibuch EE, Wang JQ, Chu ZP.
Differential Regulation of Behavioral Sensitivity to
Acute and Chronic Cocaine Administration by AcidSensing Ion Channel 1a And 2 in Adult Mice. MARC.
4-27-13. Kansas City, MO. (Second place in basic science).
CANCER INSTITUTE
Aft R, Mudalagiriyappa C, Watson M, Pillai S, Fleming
T, Trinkaus K, Pluard TJ. [OT1-1-02] A Phase II
Randomized Trial Evaluating The Effect Of
Trastuzumab On Disease Free Survival In Early
Stage HER2-Negative Breast Cancer Patients With
ERBB2-Expressing Bone Marrow Disseminated
Tumor Cells. San Antonio Breast Cancer Symposium,
San Antonio TX, 2013 December 11.
Akthar A, Schomas DA, et al. A Retrospective Analysis
of Stereotactic Body Radiotherapy (SBRT) in
Patients with Stage I Non-Small- Cell Lung Cancer
(NSCLC) or Limited Metastatic Disease to Lung.
American College of Radiation Oncology Annual Meeting,
San Antonio, TX, 2013.
42
Macdonald OK, Schomas DA. Multiple Course
Stereotactic Ablative Body Radiotherapy(SABR)
for Non-Small Cell Lung Cancer (NSCLC) in
Elderly Patients. International Stereotactic Radiotherapy
Symposium, Houston, TX, 2013.
Sikov WM, Berry DA, Perou CM, Singh B, Cirrincione
C, Tolaney S, Kuzma CS, Pluard TJ, Somlo G, Port E,
Golshan M, Bellon JR, Collyar D, Hahn OM, Carey
LA, Hudis C, Winer EP. Impact of the Addition of
Carboplatin (Cb) and/or Bevacizumab (B) to
Neoadjuvant Weekly Paclitaxel (P) Followed by
Dose-Dense AC on Pathologic Complete Response
(Pcr) Rates In Triple-Negative Breast Cancer
(TNBC): CALGB 40603 (Alliance). San Antonio Breast
Cancer Symposium, San Antonio TX, 2013 December 13.
Ward WG, Monn MC. Developing a Current Good
Manufacturing Practice (cGMP)-Compliant Cell
Therapy Laboratory Culture through a Cycle of
Education, Training, Auditing, and Improvement.
American Association of Blood Banks Annual Meeting,
Denver CO, 2013 October.
EMERGENCY MEDICINE
Gaddis G. Emergency Department Screening for
Sepsis, Central European Congress for Emergency
Medicine and Critical Care, Karpacz, Poland, April
2013.
Gaddis, G. The Emergency Department: A System
within a System. Understanding Patient Thoughput
in the Emergency Department, Central European
Congress for Emergency Medicine and Critical
Care, Karpacz, Poland, April 2013.
Gaddis, G. Accomplishing Clinical Research with
Limited Funds, Central European Congress for
Emergency Medicine and Critical Care, Karpacz,
Poland, April 2013.
Gaddis, G. Differentiating Non-Inferiority Studies,
7th Mediterranean Emergency Medicine Congress,
Marseille, France, September, 2013.
Gaddis, G. Pitfalls in Research Methodology. 7th
Mediterranean Emergency Medicine Congress,
Marseille, France, September, 2013.
Gaddis G. Non-emergent Psycho-behavioral
Disorders in the ED. Recorded for Audio Digest
Emergency Medicine, September, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
GASTROENTEROLOGY
Chhabra R, O’Keefe JH, Patil H, O’Keefe E, Thompson
RC, Ansari S, Kennedy KF, Lee L, Helzberg JH. Hepatic
Steatosis is an Independent and a Strong Predictor of
Coronary Artery Disease in Asymptomatic Patients,
Beyond That Expected from Traditional Framingham
Risk Factors and Metabolic Syndrome. American
Gastroenterological Association, Orlando, May 2013.
HEPATOLOGY AND HEPATOBILIARY
SURGERY
Poordad F, Rustgi V, Brown R, Patel V, Kugelmas M,
Regenstein F, Balart L, LeBrecque D, Brown K, Avila M,
Bierderman M, Freed G, Smith R, Bernstein M, Hays A,
Cahan J, Fink S, Katakov W, Massoumi M, Harrison S.
Boceprevir (BOC) In Community Practice: Interim
Results On Early Response And Safety From The
OPTIMAL Trial. Presented at the Annual Meeting of the
American College of Gastroenterology, San Diego, October,
2013.
Brown K, Bacon B, Balart L, Bernstein D, Brown R,
Flamm S, Harrison S, Kugelmas M, Kwo P, Lebrecque D,
Neff G, Patel V, Reau N, Reddy R, Regenstein F, Schiff
E, Shiffman M, Poordad F. Hepatitis C Therapy In
Community Practice (OPTIMAL): An Educational
Partnership Program Between Academic And
Community Practice. Presented at the Annual Meeting
of the American College of Gastroenterology, San Diego,
October, 2013.
Afdhal NH, Reau N, Everson GT, Morelli G, Lok AS,
Sherman KE, Dickson RC, Regenstein F, Mean EA,
Stewart TG, Fried MW, Pockros P for the HCVTARGET Study Group. Safety and Efficacy of
Telaprevir (TPV) or Boceprevir (BOC) in Patients
with Cirrhosis: Interim Results of a Longitudinal,
Observational Study. American Association for the Study
of Liver Diseases. Washington, DC. November 2013
Burden of Angiographic Coronary Disease: A Post
Hoc Analysis of the COURAGE Trial. American Heart
Association Scientific Sessions. Dallas, TX. November 1620, 2013.
Acharjee S, Sidhu MS, Hartigan PM, Teo KK, Spertus JA,
Maron D, Weintraub WS, Boden WE. Impact of Angina
on Cardiovascular Outcomes in Patients with Stable
Ischemic Heart Disease: A Post-Hoc Analysis from
the COURAGE Trial. American Heart Association
Scientific Sessions. Baltimore, MD. November 16-20, 2013.
Allen KB, Borkon AM, Aggarwal S, Haines M, Davis
R, Sydzyik T, Pak A, Stewart J, Stuart RS, Allen
KE. Venoarterial Extracorporeal Membrane
Oxygenation: Simplified Tunneled Technique Using
Arterial Grafting and Saphenofemoral Cannulation.
ISMICS 2013 Prague, Czech Republic. Innovations
2013;8(2):128.
Allen KB, Foreman J, Khicha S, Puggioni A, Borkon
AM, Laster S, Aggarwal S, Davis JR, Allen KE. Primary
Coarctation of the Aorta Diagnosed in the Older
Patient: Endovascular Treatment with Thoracic
Covered Stents. ISMICS 2013 Prague, Czech Republic.
Innovations 2013;8(2):149.
Allen KB, Fowler VG, Gammie JS, Hartzel J, Onorato M,
Dinubible M, Sobanjo-Ter Meulen A. Staphylococcus
Aureus Infections after Elective Cardiac Surgery:
Observations from a Multicenter Placebo-Controlled
Trial of an Investigational Vaccine. Infection Disease
Society of America San Francisco, CA. October 2-6, 2013.
Allen KB. Current Reimbursement and Patientreported Outcomes in Venous Disease: What does
the Future Hold? American Venous Forum 25th Annual
Meeting Scottsdale, AZ. February 2013.
Allen KB. Cardiothoracic and Vascular Surgery:
What’s New and Exciting? Greater KC Nurses
Association Meeting Kansas City, MO. February 2013.
Allen KB. TMR Evidence based Applications and
Future Directions. Atlanta, GA. January 2013.
MID AMERICA HEART INSTITUTE
Abdallah MS, Kosiborod M, Tang F, Karrowni WY,
Maddox TM, McGuire DK, Spertus JA, Arnold SV.
Patterns and Predictors of Intensive Statin Therapy
among Patients with Type 2 Diabetes Mellitus after
an Acute Myocardial Infarction. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Acharjee S, Sidhu MS, Hartigan PM, Teo KK, Maron
DJ, Sedlin SP, Mancini GBJ, Chaitman BR, Spertus JA,
Weintraub WS, Boden WE. Sex-Based Comparison of
Angina Severity, Extent of Inducible Ischemia and
Allen KB. Decision-making in Critical Limb
Ischemia: What a Cardiac Surgeon Needs to Know.
Society of Thoracic Surgery Los Angeles, CA. February
2013.
Allen LA, Magid DJ, Shetterly S, Peterson PN, Brand
DW, Bekelman DB, Clarke CL, Spertus JA, Masoudi
FA. Incremental Prognostic Value of Serial Health
Status Measures for Ambulatory Patients with Heart
Failure. Quality of Care & Outcomes Research Scientific
Sessions. Baltimore, MD. May 15-17, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
43
Amin AP Bach RG, Kosiborod M, Kennedy K, Tsai
TT, Brown JR, Chhatriwalla AK, Cohen DJ, Spertus
JA. Large Variation in Contrast Use During PCI
- An Important Opportunity for Reducing Acute
Kidney Injury. Circ Cardiovasc Qual Outcomes 2013
May;6:A354. Baltimore, MD. May 15-17, 2013.
Amin AP, House J, Safley D, Chhatriwalla A, Giersiefen
H, Bremer A, Hamon M, Baklanov D, Aluko Y, Wohns
D, Mathias D, Applegate R, Cohen D, Marso SP. Costs
of Transradial and Transfemoral PCI at Five U.S.
Hospitals. J Am Coll Cardiol 2013 Mar;61(10S):210. San
Francisco, CA. March 9-11, 2013.
Amin AP, Patterson M, House J, Kennedy K, Bremer A,
Giersiefen H, Spertus JA, Baklanov D, Chhatriwalla A,
Safley D, Cohen D, Rao S, Marso SP. Transradial PCI
is Associated with Lower Cost in Medicare Fee-forService Beneficiaries Following Elective PCI. J Am
Coll Cardiology 2013, American College of Cardiology
52nd Annual Scientific Sessions. San Francisco, CA. March
9-11, 2013.
Amin AP, Shapiro R, Novak E, Olsen M, Singh J, Bach
RG, Cohen DJ. Costs of Contrast Induced Acute
Kidney Injury. Circ Cardiovasc Qual Outcomes 2013
May;6:A316. Baltimore, MD. May 15-17, 2013.
Arnold S, Kirtane A, Kodali S, Zajarias A, Thourani V,
Green P, Rodes-Cabau J, Alu M, Lei Y, Mack M, Leon
M, Cohen D. Predictors of Poor Outcome After
Transcatheter Aortic Valve Replacement in the
PARTNER Trial. J Am Coll Cardiology 2013; American
College of Cardiology 52nd Annual Scientific Sessions. San
Francisco, CA. March 9-11, 2013.
Arnold SV, Kosiborod M, Li Y, Jones PG, Yue P, Belardinelli
L, Spertus JA. Comparison of the Seattle Angina
Questionnaire with Daily Angina Diary Entry.
American Heart Association Scientific Sessions. Dallas, TX.
November 16-20, 2013.
Arnold SV, Kosiborod M, Li Y, Yue P, Ben-Yehuda O,
Belardinelli L, Katz A, Jones PG, Olmsted A, Chairman BR,
Spertus JA. Effects of Ranolazine on Disease-Specific
Health Status and Quality of Life Among Patients
with Diabetes and Stable Angina: Results from the
TERISA Randomized Trial. American Heart Association
Scientific Sessions. Dallas, TX. November 16-20, 2013.
Arnold SV, McGuire DK, Lipska KJ, Tang F, Spertus JA,
Goyal A, Gore MO, Lanfear DE, Maddox TM, Kosiborod
M. Type of Beta Blocker Use Among Patients With
versus Without Diabetes after Myocardial Infarction.
Quality of Care & Outcomes Research Scientific Sessions.
Baltimore, MD. May 15-17, 2013.
44
Arnold SV, McGuire DK, Spertus JA, Li Y, Yue P, BenYehuda O, Belardinelli L, Katz A, Jones PG, Olmsted
A, Chaitman BR, Kosiborod M. Effectiveness of
Ranolazine in Patients with Type 2 Diabetes Mellitus
and Chronic Stable Angina According to Baseline
Hemoglobin A1c. American Heart Association Scientific
Sessions. Dallas, TX. November 16-20, 2013.
Arnold SV, Spertus J, Lipska K, Tang F, Goyal A, McGuide
D, Cresci S, Maddox T, Kosiborod M. Association of
Diabetes Mellitus with Post-Myocardial Infarction
Angina: Analysis of the TRIUMPH Prospective
Cohort Study. American College of Cardiology Scientific
Sessions San Francisco, CA. March 9-11, 2013.
Arnold SV, Spertus JA, Alexander KP, Bach RG, Wang TY,
Krumholz HM, Li Y, Jones PG, Kosiborod M. HospitalLevel Variability in the Use of Angicoagulant
Strategies in a Real-World Population of Patients
with Acute Myocardial Infarction. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Arnold SV, Spertus JA, Lei Y, Green P, Kirtane AJ, Kapadia
S, Thourani VH, Herrmann HC, Ceohar N, Zajarias
A, Mack MJ, Leon MB, Cohen DJ. Defining Futility
in Transcatheter Aortic Valve Replacement. Circ
Cardiovasc Qual Outcomes 2013 May; 6:A69. Baltimore,
MD. May 15-17, 2013.
Baklanov D, Tang F, Safley D, Fuss C, Jones P, Spertus J.
Short Term Health Status Outcomes and Preferences
in Patients Undergoing Elective Transradial
Coronary Intervention. Quality of Care & Outcomes
Research Scientific Sessions. Baltimore, MD. May 15-17,
2013.
Bateman TM. Is PET Really Better? Comparative
Advantages over SPECT, Advances in Nuclear
Cardiology and Cardiac CT, Challenges and
Opportunities for SPECT and PET in 2013. 28th
Annual Case Review with the Experts Los Angeles, CA.
January 19, 2013.
Bateman TM. PET and CTA: How to Use Hybrid
Imaging Effectively. American College of Cardiology
52nd Annual Scientific Sessions. San Francisco, CA. March
11 2013.
Bateman TM. Challenges & Opportunities for
SPECT and PET in 2013, PET vs SPECT for MPI:
Comparative Advantages. 35th Annual Recent Advances
in Clinical Nuclear Cardiology & Cardiac CT. Washington,
DC. May 8, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
Bateman TM. Reducing Radiation While Maintaining
Quality, Rubidium-82: Past, Present and Future,
A Snapshot of Equipment Utilization in the United
States. Society of Nuclear Medicine 2013 Annual
Meeting. Vancouver, British Columbia. June 9-13, 2013.
Bateman TM. Verani Memorial Lecture: Vision,
Leadership & Change, Cardiac Imaging in a
Capitated Environment, Cardiac PET Case
Presentations, Private Practice Perspective.
American Society of Nuclear Cardiology 2013 Annual
Meeting. Chicago, IL. September 26-29, 2013.
Bateman TM. Strategies and Challenges in the Quest
for Reducing Dosimetry for Myocardial Perfusion.
Should Your Next Cardiac Camera be a PET
Scanner? Rocky Mountain Nuclear Medicine Technologist
Annual Meeting. Denver, CO. October 5, 2013.
Bateman TM. Positron Emission Tomography:
Enhancing the Value of Myocardial Perfusion for
Appropriate Patients. Cardiology Grand Rounds Allegheny Health Network. Pittsburgh, PA. October 9, 2013.
Bateman TM. Positron Emission Tomography:
Enhancing the Value of Myocardial Perfusion for
Appropriate Patients. Twelfth Annual Mario S. Verani
Memorial Lectureship, Houston Methodist DeBakey Heart
and Vascular Center. Houston, TX. October 17, 2013.
Bateman TM. Case-Based Face-Off: SPECT vs PET
for MPI. American Society of Nuclear Cardiology: Local
Learning Initiative. Kansas City, MO. October 24, 2013.
Bateman TM. Rubidium-82 Cardiovascular PET and
Coronary Flow Reserve. 53rd Annual Japanese Society
of Nuclear Medicine. Fukuoka, Japan. November 9, 2013.
Bikdeli B, Wang Y, Minges K, Nallamothu BK, Kim
N, Desai M, Masoudi FA, Spertus JA, Goldhaber SA,
Krumholz HM. Trends in Use of Thrombolytic
Therapy among Fee-for-Service Medicare
Beneficiaries with Acute Pulmonth Embolism.
American Heart Association Scientific Sessions. Dallas, TX.
November 16-20, 2013.
Bikdeli B, Wayda B, Bao H, Ross J, Xu X, Chaudhry
S, Spertus J, Krumholz H. Place of Residence and
Outcomes of Patients with Heart Failure: An
Analysis from the Tele-HF Trial Participants.
American College of Cardiology Scientific Sessions. San
Francisco, CA. March 9-11, 2013.
Bindra A, Teo K, Sidhu M, Hartigan P, Maron D, Kostuk
W, Sedlis S, Mancini GBJ, Bates E, Scirica B, Spertus J,
Weintraub W, Chaitman B, Boden W. Prevalence and
Clinical Significance of Recurrent and Unremitting
Angina with Percutaneous Intervention versus
Optimal Medical Therapy in Patients with Stable
Ischemic Heart Disease: A Post Hoc Analysis of
the Clinical Outcomes Utilizing Revascularizatio
American College of Cardiology Scientific Sessions San
Francisco, CA. March 9-11, 2013.
Bradley SM, Spertus JA, Nallamothu BK, Chan PS,
Kennedy KJ, Patel MR, Bryson CL, Malenka DJ, Rumsfeld
JS. The Association Between Patient Selection for
Diagnostic Coronary Angiography and HospitalLevel PCI Appropriateness: Insights from the
NCDR. Quality of Care & Outcomes Research Scientific
Sessions. Baltimore, MD. May 15-17, 2013.
Brown PP, Kugelmass A, Reynolds M, Cohen D, Culler S,
Simon A. The Incremental Hospital Cost of Treating
Major Complications Among Medicare Beneficiaries
Undergoing Coronary Artery Bypass Graft Surgery.
J Am Coll Cardiology 2013 Mar;61(10S):A397. American
College of Cardiology 52nd Annual Scientific Sessions San
Francisco, CA. March 9-11, 2013.
Buchanan DM, Bennett KK, Reid K, Spertus JA. Cardiac
Rehabilitation Referral After Acute Myocardial
Infarction: Variation in Referral Rates and
Association with Core Components of Risk Factor
Management. Quality of Care & Outcomes Research
Scientific Sessions. Baltimore, MD. May 15-17, 2013.
Buchanan DM. Patient-Centered Cardiovascular
Translational Research: Examples from Genomics
to Shared Decision-Making. Patient Centered
Translational Discovery Forum, University of Kansas Edwards Campus. Overland Park, KS. November 6, 2013.
Chan PS. In-Hospital Cardiac Arrest: An Agenda for
the Next Decade. American Heart Association Dickinson
W. Richards Memorial Lecturer at AHA Scientific Sessions.
Dallas, TX. November 16-20, 2013.
Chen J, Wang H, Fazal R, Normand ST, Bradford D,
Al-Mallah M, Cohen DJ, Spettell C, Fernandez J, Shaw
L, Krumholz HM, Nallamothu BN. Does Higher Use
of Non-Invasive Testing Improve the Diagnostic
Yield of Coronary Angiography? Circ Cardiovasc Qual
Outcomes 2013 Baltimore, MD. May 15-17, 2013.
Chen LM, Nallamothu BK, Krumholz HM, Spertus JA,
Tang F, Chan PA. Association Between a Hospital’s
Quality Performance for In-Hospital Cardiac Arrest
and Common Medical Conditions. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
45
Chhatriwalla AK Cost Analysis: Is It Still Cost
Effective to Use Prasugrel or Ticagrelor vs. Generic
Clopidogrel? Cardiovascular Research Technology (CRT)
2013 Washington, DC. February 14, 2013.
Cohen DJ. Quality of Life After TAVR: What Should
you Know? Why Should you Care? Italian Society of
Invasive Cardiology Annual Scientific Meeting Genoa, Italy.
June 22-26, 2013.
Chhatriwalla AK Aortic Stenosis: New Treatment
Paradigms. Missouri ACC Chapter Annual Meeting St.
Louis, MO. October 5, 2013.
Cohen DJ. Improving PCI Quality: Targets for 2013
and Beyond. Principles and Perspectives in Interventional
Cardiology Maui, Hawaii. July 15-19, 2013.
Chilton RJ, MacConell LA, Han JC, Marso SP.
Characterization of Heart Rate Increases with
Glucagon-like Peptide-1 Agonist Therapy. American
Heart Association Scientific Sessions. Dallas, TX. November
16-20, 2013.
Cohen DJ. PARTNER Trial Update: What Have
We Learned? Where Are We Going? Principles and
Perspectives in Interventional Cardiology Maui, Hawaii. July
15-19, 2013.
Cohen DJ. Everolimus Eluting Stents Reduce Stent
Thrombosis (Maybe): Challenges of Network Metaanalysis. American College of Cardiology Scientific
Sessions/I-2 Summit San Francisco, CA. March 9-11, 2013.
Cohen DJ. Controversies in STEMI Management:
Universal vs Selective Use of DES American College of
Cardiology Scientific Sessions/I-2 Summit San Francisco,
CA. March 9-11, 2013.
Cohen DJ. ASCERT: Comparative Effectiveness in
the Real World American College of Cardiology Scientific
Sessions/I-2 Summit San Francisco, CA. March 9-11, 2013.
Cohen DJ. Can We Afford TAVR? 18th Annual
Angioplasty Summit-TCT Asia Pacific Seoul Korea. April
22-26, 2013.
Cohen DJ. Resisting the Bioabsorbable Stent
Bandwagon 18th Annual Angioplasty Summit-TCT Asia
Pacific Seoul Korea. April 22-26, 2013.
Cohen DJ. What’s New in Multivessel Disease: Insights
from Recent Clinical Trials 18th Annual Angioplasty
Summit-TCT Asia Pacific Seoul Korea. April 22-26, 2013.
Cohen DJ. Defining Value in the Cath Lab: Can We
Measure it? Can We Improve it? Society for Cardiac
Angiography and Intervention (SCAI) National Meeting
Orlando, FL. May 7-9, 2013.
Cohen DJ. Economics of TAVR: A Global “Gordian
Knot” Transcatheter Valve Therapeutics Meeting
Vancouver, British Columbia. June 11-13, 2013.
Cohen DJ. Can We Afford TAVR? Impact on Hospitals
and Health Systems Transcatheter Valve Therapeutics
Meeting Vancouver, British Columbia. June 11-13, 2013.
Cohen DJ. Barriers to the Adoption of Evidencebased Therapies: The Case of Antiplatelet Therapy
Melbourne, Australia. June 13-17, 2013.
46
Cohen DJ. Building a TAVR Program: Insights from
the MAHI Experience. Principles and Perspectives in
Interventional Cardiology Maui, Hawaii. July 15-19, 2013.
Cohen DJ. Improving PCI Outcomes: The Role
of Personalized Medicine Australia-New Zealand
Endovascular Technologies (ANZET) Meeting Australia.
August 4-9, 2013.
Cohen DJ. PCI for Chronic CAD: Does It have a Role
in 2013? Australia-New Zealand Endovascular Technologies
(ANZET) Meeting Australia. August 4-9, 2013.
Cohen DJ. How Can We Improve the Costeffectiveness of TAVR for Lower-Risk Patients?
London Valves Meeting London, England. September 1517, 2013.
Cohen DJ. Invited Speaker 25th Transcatheter
Cardiovascular Therapeutics (TCT) Symposium San
Francisco, CA. October 2-6, 2013.
Cohen DJ. Invited Speaker American Heart Association
Annual Scientific Sessions. Dallas, TX. November 16-20, 2013.
Decker CJ, Chhatriwalla E, Garavalia B, Spertus JA,
Chen E, Gialde E. Differing Perspectives Between
Physicians, Patients and Caregivers on the Value
of an Individualized Estimate of the Benefits of
Thrombolysis at the Time of Acute Ischemic Stroke:
Designing The Resolve (Rapid Evaluation for Stroke
Outcomes using Lytics i Quality of Care & Outcomes
Research Scientific Sessions. Baltimore, MD. May 15-17,
2013.
Depta J, Lenzini P, Lanfear D, Wang T, Spertus J, Bach
R, Cresci S. Clinical Outcomes Associated with
Proton Pump Inhibitor use Among ClopidogreloTreated Patients within CYP2C19 /Genotype
Groups Following Acute Myocardial Infarction in
TRIUMPH Category: Acute Coronary Syndromes,
Myocardial Infarction, Thrombectomy and V Society
for Cardiovascular Angiography & Interventions Scientific
Sessions. Orlando, FL. May 8-11, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
Dodson JA, Wang U, Alexander KP), Masoudi F, Spertus
JA, Chaudhry SI, Chen J, Nallamothu BK, Arnold SV,
Dharmarajan K, Shi R, Krumholz HM. National Trends
in Rehospitalization for Bleeding after Acute
Myocardial Infarction in Older Patients, 1999-2010.
American Heart Association Scientific Sessions. Dallas, TX.
November 16-20, 2013.
Doll JA, Tang F, Cresci S, Parashar S, Ho M, Spertus JA,
Wang TY. Change in Angina Symptom Status after
Acute Myocardial Infarction and Its Association with
Readmission Risk: An Analysis of the TRIUMPH
Registry. American Heart Association Scientific Sessions.
Dallas, TX. November 16-20, 2013.
Dreyer RP, Smolderen KG, Strait KM, Beltrame JF,
Lichtman JH, Lorenze NP, D’Onofrio G, Krumholz HM,
Spertus JA. Sex Differences in Pre-Event Health
Status of Young Patients with Acute Myocardial
Infarction: The VIRGO Study. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Enriquez JR, De Lemos JA, Parikh SV, Holmes D, Wang
TY, Chan PS, Spertus JA, Das SR. The Association of
Electronic Health Record Use with Acute MI Quality
of Care and Outcomes: Results from the NCDR®.
American Heart Association Scientific Sessions. Dallas, TX.
November 16-20, 2013.
Fosbel EL, Peterson E, Honeycutt E, Zettler M, Messenger
J, Waksman R, Effron M, Vaitkus P, Cohen D, Wang T. Early
Cessation of ADP Receptor Inhibitors Among Acute
Myocardial Infarction Patients Treated with PCI:
Insights from the TRANSLATE-ACS Study. J Am
Coll Cardiol 2013 Mar;61(10S):A394. San Francisco, CA.
March 9-11, 2013.
Girotra S, Cram P, Spertus JA, Li Y, Jones P, Nallamothu
BK, Chan PS. Variation in Survival Trends for InHospital Cardiac Arrest. American Heart Association
Scientific Sessions. Dallas, TX. November 16-20, 2013.
Grantham JA. Course Co-Director and Faculty
Member. 10th International Left Main and Chronic Total
Occlusion Summit. New York City, NY. February 4-5, 2013.
Grantham, JA. Indication for CTO PCI: Clinical
Rationale and Appropriateness. Cardiovascular
Research Technology (CRT) 2013 Washington, DC.
February 24, 2013.
Grantham, JA. Trends in Initial Guidewire
Selection for Antegrade and Retrograde Approach
Cardiovascular Research Technology (CRT) 2013
Washington, DC. February 24, 2013.
Grantham, JA. Complications of CTO PCI
II: Perforation - Predictors, Prevention and
Management. Cardiovascular Research Technology
(CRT) 2013 Washington, DC. February 24, 2013.
Grantham, JA. Committee Member, Scientific Session
Planning Committee for TCT at ACC 2013, and
Faculty Member. American College of Cardiology 2013
Annual Scientific Sessions. San Francisco, CA. March 9-11,
2013.
Grantham, JA. Selecting Appropriate Patients for
CTO-PCI. TCT-American College of Cardiology 2013
San Francisco, CA. March 9-11, 2013.
Grantham, JA. PCI: Successes, Challenges and
Implementation. American College of Cardiology 2013
Annual Scientific Sessions. San Francisco, CA. March 9-11,
2013.
Grantham, JA. Do we Need BP Device in General
CTO-PCI? Nagoya, Japan. May 9, 2013.
Grantham, JA. Fight over Knuckle or Tackle? Nagoya,
Japan. May 9, 2013.
Grantham, JA. Role of Retrograde Approach in Hybrid
Approach. Nagoya, Japan. May 9, 2013.
Grantham, JA. PCI for CTO is Indicated in Far More
Situations than Currently Practiced/Recommended.
Complex Cardiovascular Catheter Therapeutics. Orlando,
FL. June 19, 2013.
Grantham, JA. Changing a Non-dedicated CTO
Operator into a Routine CTO Operator. Complex
Cardiovascular Catheter Therapeutics. Orlando, FL. June
19, 2013.
Grantham, JA. Indications and Appropriateness of
CTO PCI Principles and Perspectives in Interventional
Cardiology Maui, Hawaii. July 15-19, 2013.
Grantham, JA. Antegrade Dissection and Re-Entry
Strategies. Principles and Perspectives in Interventional
Cardiology Maui, Hawaii. July 15-19, 2013.
Grantham, JA. Revascularization: CABG vs PCI: Is
There a Right Choice? ACC Missouri Chapter Update in
Cardiovascular Disease St. Louis, MO. October 5, 2013.
Grantham, JA. CTO PCI Justification: Making the Case
with Evidence. TCT 2013 Scientific Committee and
Faculty. San Francisco, CA. October 28-31, 2013.
Grantham, JA. The Retrograde Approach to CTOs in
Association with CCT. TCT 2013 Scientific Committee
and Faculty. San Francisco, CA. October 28-31, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
47
Grantham, JA. My Most Difficult Retrograde Approach
Case in 2013. TCT 2013 Scientific Committee and
Faculty. San Francisco, CA. October 28-31, 2013.
Grantham, JA. Chronic Total Occlusions: The Essential
Technique of CTO Recanalization: Algorithm and
Approach. TCT 2013 Scientific Committee and Faculty.
San Francisco, CA. October 28-31, 2013.
Grantham, JA. A Brief History of Antegrade Dissection
Reentry (ADR): Techniques, Technologies and
Current Best Practices. TCT 2013 Scientific Committee
and Faculty. San Francisco, CA. October 28-31, 2013.
Green P, Kirtane A, Genereux P, McAndrew T, Hueter I,
Alu M, Arnold S, Beohar N, Rihal C, Mack M, Kapadia
S, Mauer M, Williams M, Kodali S, Leon M,Cohen D.
The Impact of Six-Minute Walk Test Performance
on Outcomes After Transcatheter Aortic Valve
Replacement: Insights from the PARTNER Trial. J
Am Coll Cardiology 52nd Annual Scientific Sessions San
Francisco, CA. March 9-11, 2013.
Grodzinsky A, Arnold SV, Gosch K, Spertus JA, Parashar S,
Maddox TM, Kosiborod M. Frequency of Angina after
Acute Myocardial Infarction Among Patients with
Nonobstructive Coronary Artery Disease. American
Heart Association Scientific Sessions. Dallas, TX. November
16-20, 2013.
Gukathasan N, Weisz G, Witzenbichler B, Kini A, Henry
T, Sartori S, Baber U, Cohen D, Chieffo A, Hermiller J,
Stuckey T, Shawl F, Moliterno D, Antoniucci D, Berger P,
Waksman R. Frequency and Impact of Single versus
Dual Antiplatelet Cessation on Adverse Cardiac
Events: Results from the PARIS Registry. J Am Coll
Cardiology 52nd Annual Scientific Sessions San Francisco,
CA. March 9-11, 2013.
Gupta A, Wang Y, Spertus J, Geda M, Lorenze N,
D’Onofrio G, Lichtman J, Krumholz H. Sex-Specific
Trends in Hospitalizations among Young Patients
with Acute Myocardial Infarction in United States,
2001-2010. American College of Cardiology Scientific
Sessions San Francisco, CA. March 9-11, 2013.
Gupta S. Anticoagulation in Atrial Fibrillation: A
Shifting Paradigm. Physician Continuing Education
Seminar, Western Missouri Medical Center. Warrensburg,
MO. June 20, 2013.
Gupta S. A Novel Approach to Screening for Sleep
Apnea Utilizing Data from Implantable Cardioverter
Defibrillators - Poster. Heart Rhythm Society 34th
Annual Scientific Sessions. Denver, CO. May 8-11, 2013.
Gupta S. Two EP Case Presentations. Kansas City
Electrophysiology Master Conference. Kansas City, MO.
October 2013.
48
Hachamovitch R, Spertus J, Marwick T. Association
Between Heart Failure Diagnosis, Left Ventricular
Ejection Fraction and Measures of Patient-Assessed
Quality of Life and Functional Status. American
College of Cardiology Scientific Sessions San Francisco,
CA. March 9-11, 2013.
Harris W, Kennedy KF, Jones PG, Maddox TM, Spertus
JA. Fish Oil Supplementation in Post-Myocardial
Infarction Patients in the Triumph Study: Defining
Characteristics and Relations with Two-year
Mortality. American College of Cardiology Scientific
Sessions San Francisco, CA. March 9-11, 2013.
Hart AJ, Aksoy O, Blackstone E, Lytle B, Hachamovitch
R, Griffin B. Role of Calcium Supplementation in
Structural Valve Deterioration. American College of
Cardiology Scientific Sessions San Francisco, CA. March
9-11, 2013.
Hart AJ. Interventional Dilemmas. Geoffrey O. Hartzler
MD Interventional Cardiology Symposium: Principles &
Perspectives - State of the Art. Maui, Hawaii. July 15-19, 2013.
Hawkins BM, Kennedy K, Aronow HD, Nguyen L,
White CJ, Rosenfield K, Normand ST, Spertus JA, Yeh
RW. Hospital Variation in Carotid Artery Stenting
Outcomes: An NCDR® Analysis. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Huber KC. Left Atrial Appendage and Stroke. 43rd
Annual Dr. Robert D. Conn Heart Conference Kansas City,
MO. December 12, 2013.
Jayaram N, Buchanan D, Gosch K, Jones PG, Tollefson JE,
Spertus JA. Understanding the Protective Benefits of
Marriage on Survival After Myocardial Infarction.
American Heart Association Scientific Sessions. Dallas, TX.
November 16-20, 2013.
Jayaram N, Krumholz HM, Chaudhry SI, Mattera J, Tang
F, Spertus JA. Impact of Telemonitoring on Health
Status in Patients with Heart Failure. Quality of Care
& Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Jayaram N, Spertus J, Tang F, Chan P. Hospital Variation
in Survival for Pediatric In-Hospital Cardiac
Arrest: A Report from Get with the Guidelines Resuscitation. American College of Cardiology Scientific
Sessions San Francisco, CA. March 9-11, 2013.
Jayaram N, Spertus JA, Tang F, Chan PS. Hospital Variation
in Survival for Pediatric In-Hospital Cardiac Arrest: A
Report from Get With the Guidelines - Resuscitation.
Quality of Care & Outcomes Research Scientific Sessions.
Baltimore, MD, May 15-17, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
Jones P, Chan P, Gosch K, Li Y, Reid K, Tang F, Spertus J.
The SAQ-7: A Short Version of the Seattle Angina
Questionnaire. Quality of Care & Outcomes Research
Scientific Sessions. Baltimore, MD. May 15-17, 2013.
Kosiborod M. Predicting Cardiovascular Risk in
Diabetes - Are Emerging Markers Better than
Lipids? American Diabetes Association Scientific Sessions
Chicago, IL. June 23, 2013.
Jones P, Gosch K, Li Y, K, Tang F, Chan P, Spertus J.
The KCCQ-12: A Short Version of the Kansas City
Cardiomyopathy Questionnaire. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Kosiborod M. Predicting Cardiovascular Risk in
Diabetes - Are Emerging Markers Better than
Lipids? American Association of Clinical Chemists
Scientific Sessions. Houston, TX. July 30, 2013.
Joseph S, Novak E, Arnold S, Platts A, Roman VD, Mann
D, Spertus J. Validity and Reliability of the Kansas
City Cardiomyopathy Questionnaire in Patients
with Heart Failure and Preserved Ejection Fraction.
American College of Cardiology Scientific Sessions. San
Francisco, CA. March 9-11, 2013.
Karrowni W, Li Y, Jones P, Cresci S, Abdallah M, Maddox
T, Spertus J, Horwitz P. Prognostic Significance of
Albuminuria in Diabetic and Non-Diabetic Patients
with Recent Acute Myocardial Infarction. American
College of Cardiology Scientific Sessions. San Francisco,
CA. March 9-11, 2013.
Kherada N, Sartori S, Vadde R, Bharathi P, Cohen D,
Militerno D, Steg P, Henry T, Weisz G, Witzenbichler B,
Colombo A, Mehran R. Predictors of Dual Antiplatelet
Therapy Non-Adherence After PCI: One-Year
Insights from the PARIS Registry. J Am Coll
Cardiology 52nd Annual Scientific Sessions San Francisco,
CA. March 9-11, 2013.
Kodali SK, Williams M, Humphries K, Cohen D,
Nkomo V, Weissman N, Thourani V, Svensson L, Tuzcu
EM, McAndrew TC, Leon MB, Miller DC, Kirtain A.
Sex-Specific Differences in Late Mortality After
Transcatheter AVR in the PARTNER Trial. J Am Coll
Caridology 52nd Annual Scientific Sessions San Francisco,
CA. March 9-11, 2013.
Kolm P, Zhang Z, Spertus J, Weintraub WS. Multilevel
Analysis of Clinical Trial Data: Is It Necessary?
Quality of Care & Outcomes Research Scientific Sessions.
Baltimore, MD. May 15-17, 2013.
Kosiborod M. Evaluation of Ranolazine in Patients
with Type 2 Diabetes Mellitus and Chronic Stable
Angina - Results from the TERISA Randomized
Clinical Trial. American College of Cardiology Scientific
Sessions - Late Breaking Clinical Trials Session. San
Francisco, CA. March 8, 2013.
Kosiborod M. Management of a Diabetic Patient with
Acute Coronary Syndrome. American Association of
Clinical Endocrinologists. Phoenix, AZ. May 3, 2013.
Kosiborod M. Diabetes and Heart Disease. American
Association of Clinical Endocrinologists Heartland
Chapter. Kansas City, MO. August 24, 2013.
Kosiborod M. Personalized Management for Patients
with SIHD & Type 2 Diabetes: Examining the
Clinical Evidence. Cardiometabolic Health Congress.
Boston, MA. October 3, 2013.
Kosiborod M. What is Quality of Care in Patients
with Diabetes Hospitalized with Cardiovascular
Illness? Chicago, IL. October 12, 2013.
Kosiborod M. Continuous Glucose Monitoring
Technology in the Cardiac Patient: Does It Have
a Role? American Heart Association Scientific Sessions
- PRIDE (Planning Research in Inpatient Diabetes)
Inaugural Meeting. Dallas, TX. November 17, 2013.
Kosiborod M. Why is My Diabetic Patient so High
Risk for Coronary Artery Disease? 43rd Annual Dr.
Robert D. Conn Heart Conference Kansas City, MO.
December 13, 2013.
Kramer DB, Kennedy K, Noseworthy P, Buxton A,
Josephson M, Normand SL, Spertus J, Zimetbaum
P, Reynolds M, Mitchell SL. Characteristics
and Outcomes of Patients Receiving New
and Replacement Implantable CardioverterDefibrillators: Results from the NCDR. American
College of Cardiology Scientific Sessions San Francisco,
CA. March 9-11, 2013.
Kugelmass A, Brown PP, Reynolds M, Cohen DJ, Culler
SD, Simon AW. Concomitant Contrast Dependent
Procedures are Predictors of Increasing PCI
Associated Renal Complications Among Medicare
Beneficiaries. Circ Cardiovasc Qual Outcomes 2013
May;6:A106. Baltimore, MD. May 15-17, 2013.
Kugelmass A, Brown PP, Reynolds M, Cohen DJ, Culler
SD, Simon AW. Trends in Renal Complication Rates
among Medicare Beneficiaries Undergoing PCI:
Fiscal Years 2009 through 2011. Circ Cardiovasc Qual
Outcomes 2013 May;6:A49. Baltimore, MD. May 15-17,
2013.
2013 Research Annual Repor t // Central Office of Research Administration
49
Kulkarni VT, Ross JS, Wang Y, Nallamothu BK, Spertus
JA, Normand ST, Masoudi FA, Krumholz HM. Regional
Cardiologist Density and 30-day and 1-year
Mortality in Acute Myocardial Infarction and Heart
Failure. Quality of Care & Outcomes Research Scientific
Sessions. Baltimore, MD. May 15-17, 2013.
Kureshi F, Arnold SV, Li Y, Masoudi FA, Jones PG, Cresci
S, Maddox TM, Ho M, Spertus JA. Development of a
30-day Angina Risk Standardization Model Following
an Acute Myocardial Infarction. American Heart
Association Scientific Sessions. Dallas, TX. November 1620, 2013.
Kureshi F, Jones P, Buchanan D, Abdallah M, Spertus
J. Variability in Patient Misperceptions on the
Indication and Benefits of PCI in Stable Coronary
Artery Disease Within and Across Centers. American
College of Cardiology 52nd Annual Scientific Sessions. San
Francisco, CA. March 9-11, 2013.
Kureshi F, Jones P, Buchanan D, Abdallah M, Spertus
J. Variability in Patient Misperceptions on the
Indication and Benefits of PCI in Stable Coronary
Artery Disease Within and Across Centers. Quality of
Care & Outcomes Research Scientific Sessions. Baltimore,
MD. May 15-17, 2013.
Kureshi F, Jones PG, Abdallah M, Buchanan DM, Spertus
JA. Chronic Stable Angina Patient Misperceptions
on the Indication and Benefits of Percutaneous
Coronary Intervention: A Look at the Variation
Among Centers and Providers. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Laster S. Carotid Disease Beyond Carotid Duplex
Imaging. 43rd Annual Dr. Robert D. Conn Heart
Conference Kansas City, MO. December 12, 2013.
Lindsey J. Superficial Venous Insufficiency: Diagnosis
and Treatment Hutchinson Regional Medical Center
Hutchinson, KS. March 13, 2013.
Lindsey J. Anti-Platelets/Anticoagulants: Why We Use
Them and When we can Stop Them. 43rd Annual
Dr. Robert D. Conn Heart Conference Kansas City, MO.
December 13, 2013.
Main M. Common Contrast Artifacts and How to
Deal with Them. 23rd Annual Echo Conference Big
Island, Hawaii. January 21-25, 2013.
Main M. Health Care Reform: How Can We Survive
in this Brave New World? 23rd Annual Echo Conference
Big Island, Hawaii. January 21-25, 2013.
Main M. TAVR Imaging Cases: Complications to
Avoid. Post Implant Aortic Insufficiency - Valve in
Valve. 62nd Annual American College of Cardiology
Scientific Sessions San Francisco, CA. March 11, 2013.
Main M. How to Apply Contrast in Echo Lab. 24th
Annual American Society of Echocardiography Scientific
Sessions. Minneapolis, MN. June 29-July 2, 2013.
Main M. Integrating a Private Practice into a
Hospital Setting. 24th Annual American Society of
Echocardiography Scientific Sessions. Minneapolis, MN.
June 29-July 2, 2013.
Marso S. Transradial PCI is Associated with Lower
Cost in Medicare Fee-for-Service Beneficiaries
Following Elective PCI. Oral Presentation at the
American College of Cardiology Scientific Sessions 2013.
San Francisco, CA. March 10, 2013.
Marso S. Overreliance on Stress Testing. American
College of Cardiology Scientific Sessions. San Francisco,
CA. March 9, 2013.
Marso S. Management of the Inappropriate
Interventionalist: Who is Responsible and What is
the Future of AUC? The Society for Cardiovascular
Angiography and Interventions Scientific Sessions. Orlando,
FL. May 9, 2013.
Marso S. These AUC Are Just Wrong! Geoffrey O.
Hartzler MD Interventional Cardiology Symposium;
Inaugural Principles & Perspectives in Interventional
Cardiology - State of the Art. Maui, Hawaii. July 15, 2013.
Marso S. Clinical Data from First in Man to
SYMPLICITY Trials. Geoffrey O. Hartzler MD
Interventional Cardiology Symposium; Inaugural Principles
& Perspectives in Interventional Cardiology - State of the
Art. Maui, Hawaii. July 16, 2013.
Main M. Patent Foramen Ovale (PFO) and Stroke.
43rd Annual Dr. Robert D. Conn Heart Conference Kansas
City, MO. December 12, 2013.
Marso S. Low Cost of Transradial Access. Geoffrey
O. Hartzler MD Interventional Cardiology Symposium;
Inaugural Principles & Perspectives in Interventional
Cardiology - State of the Art. Maui, Hawaii. July 18, 2013.
Main M. Use of Contrast to Improve Quantification of
Ventricular Function. 23rd Annual Echo Conference Big
Island, Hawaii. January 21-25, 2013.
Marso S. Metabolic Effects of Renal Denervation.
American Heart Association Scientific Sessions. Dallas, TX.
November 17, 2013.
Main M. Integration of Contrast in Your Lab: Safety,
Consent, Flow. 23rd Annual Echo Conference Big Island,
Hawaii. January 21-25, 2013.
50
2013 Research Annual Repor t // Central Office of Research Administration
Marso S. What Have We Learned in the Past Year
About the Economics of Transradial Procedure?
American Heart Association Scientific Sessions. Dallas, TX.
November 20, 2013.
Qian F, Parzynski CS, Chaudhry SI, Spertus JA, Krumholz
HM. Racial Differences in Heart Failure Outcomes.
Quality of Care & Outcomes Research Scientific Sessions.
Baltimore, MD. May 15-17, 2013.
Marso S. Patient Selection for Direct Thrombin
Inhibitors During PCI. Scripps Clinic’s 24th Annual
Cardiovascular Interventions Conference. La Jolla, CA.
October 4, 2013.
Ramza B, Milasinovic G, Quartieri F, Vieau S, Li
S, Compton SJ. Real-World Experience with
Pacemakers Designed for Safe MRI Use: SureScan
Post-Approval Study. Poster Presentation, Heart
Rhythm Society 34th Annual Scientific Sessions Denver,
CO. May 8-11 2013.
Marso SP, Poulter NR, Nissen SE, Zinman B, Pocock S,
Bergenstal RM, Ravn LS, Moses AC, Buse J. Liraglutide
Effect and Action in Diabetes: Evaluation of
Cardiovascular Outcome and Results (LEADER)
Trial Design and Methods. 49th European Association
for the Study of Diabetes. Barcelona, Spain. September 23,
2013.
Marso SP. Next Generation Devices and Procedural
Details. Geoffrey O. Hartzler MD Interventional
Cardiology Symposium; Inaugural Principles &
Perspectives in Interventional Cardiology - State of the Art.
Maui, Hawaii. July 16, 2013.
Martin SS, Joshi PH, Blaha MJ, Kulkarni KR, Khokhar A,
Maddox TM, Havranek EP, Toth PP, Li Y, Spertus JA, Jones
SR. Remnant Lipoprotein Cholesterol and Mortality
after Acute Myocardial Infarction: The TRIUMPH
Prospective Multi-Center Registry. Quality of Care
& Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Nkonde-Price C, Dreyer RP, Hammond G, Strait KM,
Zhou S, Lorenze NP, Lichtman JH, D’Onofrio G,
Groeneveld PW, Spertus JA, Krumholz HM. Striking
Variation in Clinical Profiles of Young Black and
White Women with Acute Myocardial Infarction: The
VIRGO Study. American Heart Association Scientific
Sessions. Dallas, TX. November 16-20, 2013.
O’Keefe JH. You Are What You Drink: Effects of
Beverages on Cardiovascular Health and Life
Expectancy. 43rd Annual Dr. Robert D. Conn Heart
Conference Kansas City, MO. December 12, 2013.
Parashar S, Jones PG, Kontos MC, Vaccarino V, Lichtman
JH, Spertus JA. Biomarker Profile of Younger Women
After Acute Myocardial Infarction. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Paul SK, Marso SP, Maggs D, Klein K, Best JH. Longterm Cardiovascular Outcomes with Exenatide
Twice Daily Compared to Insulin: A Retrospective
Observational Study. American Diabetes Association
Scientific Sessions Chicago, IL. June 23, 2013.
Rutherford BD. History of Angioplasty: Evolution
of an Art. 43rd Annual Dr. Robert D. Conn Heart
Conference Kansas City, MO. December 13, 2013.
Saeed I. When Echo is Not Enough: The Incremental
Value of Cardiac Magnetic Resonance Imaging.
Greater KC Echo Society Annual Symposium Kansas City,
MO. April 13-14, 2013.
Saeed I. Where Does Cardiac Magnetic Resonance
Fit? International Nuclear Cardiology & Cardiac CT
Congress (ICNC) 11th Scientific Sessions Berlin,
Germany. May 6, 2013.
Saeed I. Utility of Cardiac Magnetic Resonance in
Guiding Patient Management. International Nuclear
Cardiology & Cardiac CT Congress (ICNC) 11th
Scientific Sessions Berlin, Germany. May 7, 2013.
Saeed I. Advances in Echo. International Nuclear
Cardiology & Cardiac CT Congress (ICNC) 11th
Scientific Sessions Berlin, Germany. May 7, 2013.
Saeed I. What Can MR Provide in Diagnosis of
New Heart Failure, Update on Echo, MR Guiding
Therapy. International Nuclear Cardiology & Cardiac
CT Congress (ICNC) 11th Scientific Sessions Berlin,
Germany. May 7, 2013.
Saeed I. Multimodality Review of Cardiovascular
Pathology. Missouri State Radiological Technologists
Kansas City, MO. September 28, 2013.
Saeed I. What Every General Cardiologist Should
Know About Congenital Heart Disease. ACCMissouri Chapter’s 5th Annual Update in Cardiovascular
Diseases. St. Louis, MO. October 5, 2013.
Safley DM, Venkitachalam L, Kennedy K, Cohen D.
Clinical Outcomes Following Glycoprotein 2b/3a
Inhibition in PCI for Acute Coronary Syndrome:
Insights from the NCDR. J Am Coll Cardiology 2013
Mar;61(10S):A475. San Francisco, CA. March 9-11, 2013.
Safley DM. Stenting Improves Quality of Life for
Patients with PAD. Vascular Interventional Advances
Meeting (VIVA). Las Vegas, NV. October 8, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
51
Salisbury AC, Spertus J, Reid K, Amin A, Gosch K,
Kosiborod M. Variation in Blood Transfusion
Practices at the Time of Acute Myocardial Infarction:
An Analysis of Consecutive Patients from 48 U.S.
Hospitals. American College of Cardiology Scientific
Sessions. San Francisco, CA. March 9-11, 2013.
Smolderen K, Elshof J, van Zitteren M, Spertus JA, Denollet
J, Nooren M, Heyligers J, Vriens PW. Lipid Control in
Patients with New Symptoms of Peripheral Arterial
Disease Evaluated at Vascular Specialty Clinics.
Quality of Care & Outcomes Research Scientific Sessions.
Baltimore, MD. May 15-17, 2013.
Sauser K, Spertus JA, Pierchala L, Pang PS. Use of the
Kansas City Cardiomyopathy Questionnaire to
Assess Acute Heart Failure Patients. Quality of Care
& Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Spatz ES, Matlock DD, Li Y, Spertus JA, Krumholz HM.
Medical Decision-Making: Preferences and Practices
in the Year Following Acute Myocardial Infarction.
Quality of Care & Outcomes Research Scientific Sessions.
Baltimore, MD. May 15-17, 2013.
Shi R, Wang Y, Lichtman JH, Charmarajan K, Masoudi FA,
Dodson JA, Chen J, Chaurhry SI, Spertus JA, Nallamothu
BK, Krumholz HM. National and Regional Trends in
Hospitalizations for Hemorrhagic Stroke after Acute
Myocardial Infarction in the United States: 19992010. Quality of Care & Outcomes Research Scientific
Sessions. Baltimore, MD. May 15-17, 2013.
Spertus JA. Quality Improvement and Evidence
Implementation Research. 5th Annual Methods
Seminar in Outcomes Research: Patient Safety. University
of Alabama, Birmingham, AL. February 26, 2013.
Shore S, Maddox TM, Bradley SM, Li Y, Spertus JA, Ho
M. Utilization of Guideline-Concordant Therapies in
Longitudinal Care after Myocardial Infarction as a
Function of Patient Risk. American Heart Association
Scientific Sessions. Dallas, TX. November 16-20, 2013.
Skolnick D. Cardiology: Everyday Issues in Office
Practice. Primary Care Physician Meeting. Big Island,
Hawaii. October 21, 2013.
Skolnick D. Interpreting ECGs, from Easy to Hard.
Primary Care Physician Meeting. Big Island, Hawaii.
October 22, 2013.
Skolnick D. Novel Anticoagulants: Which One Should I
Use? Primary Care Physician Meeting. Big Island, Hawaii.
October 23, 2013.
Skolnick D. Heart Failure Cases: A Review of
Common Etiologies and Treatments. Primary Care
Physician Meeting. Big Island, Hawaii. October 23, 2013.
Skolnick D. Stroke Prevention in Atrial Fibrillation Novel Anticoagulants. 43rd Annual Dr. Robert D. Conn
Heart Conference Kansas City, MO. December 12, 2013.
Smolderen K, Decker C, Garavalia B, Scott KM,
Chhatriwalla EG, Nugent K, Daniel WC, Rivas-Gotz C,
Mena C, Spatz E, Stilp E, Spertus JA. Listening to a
Diversity of Patient Voices to Design a High Quality
Peripheral Arterial Disease Registry Focusing
on Patient-Centered Outcomes. Quality of Care &
Outcomes Research Scientific Sessions. Baltimore, MD.
May 15-17, 2013.
Spertus JA. How to Set Up an Acute Coronary
Syndrome Performance Improvement Program.
Meet the Experts Session at the American College of
Cardiology Scientific Sessions. San Francisco, CA. March
9, 2013.
Spertus JA. Should we Monitor Patients with Quality
of Life Instruments? How Should We Monitor the
Patient with Heart Failure? American College of
Cardiology Scientific Sessions Symposium. San Francisco,
CA. March 10, 2013.
Spertus JA. Quality of Life - What about the Patient?
Quality of Life and Patient Satisfaction in a Clinical
Focus Entitled Management Dilemmas in Chronic
Coronary Heart Disease. American Collegel of
Cardiology Scientific Sessions. San Francisco, CA. March
10, 2013.
Spertus JA. Implementation of Comparative
Effectiveness Research. University of Washington
Comparative Effectiveness Conference. St. Louis, MO.
April 18, 2013.
Spertus JA. Overview of Personalized Medicine in
NCDR: Opportunities to Improve the Safety and
Quality of PCI. American College of Cardiology CQC/
NCDR Meeting. Washington, DC. April 28, 2013.
Spertus JA. Comparative Effectiveness Research to
Practice. Translating Joint ACC CQC/NCDR Meeting
Heart House. Washington, DC. May 29, 2013.
Spertus JA. Personalized Medicine to Improve the
Health and Outcomes of Women in Cardiovascular
Disease FDA Health of Women Conference. Silver
Springs, MD. June 24, 2013.
Spertus JA. Personalizing Care for PCI. Hongzhou
Interventional Conference. Hongzhou, China. August 4, 2013.
52
2013 Research Annual Repor t // Central Office of Research Administration
Spertus JA. Outcomes Research as a Foundation for
Personalized Medicine. University of Tilberg Vascular
Rounds. Tilberg, The Netherlands. September 4, 2013.
Spertus JA. Delivering Personalized Medicine
Today. Plenary Speaker, University Health Consortium
Cardiovascular Conference, Ohio State University.
Columbus, OH. September 12, 2013.
Spertus JA. Quantifying Quality of Life in Stable
Ischemic Heart Disease. Transcatheter Cardiovascular
Therapeutics Conference. San Francisco, CA. October 28,
2013.
Spertus JA. Benefits of Revascularization in
Improving QOL in SIHD: Metrics, Magnitude
and Patient Selection. Transcatheter Cardiovascular
Therapeutics Conference. San Francisco, CA. October 29,
2013.
Spertus JA. Defining the Optimal Role of AUC in Your
Cath Lab. Transcatheter Cardiovascular Therapeutics
Conference. San Francisco, CA. October 30, 2013.
Spertus JA. What Really Matters: Integrating Hard
Endpoints, Quality of Life and Patient Preferences.
Transcatheter Cardiovascular Therapeutics Conference.
San Francisco, CA. October 30, 2013.
Spertus JA. Plenary Presentation on New Paradigms
and Opportunities in Research - Determining
What Matters to Patients - Using Patient Reported
Outcomes. American Heart Association Scientific
Sessions. Dallas, TX. November 16-20, 2013.
Spertus JA. Young Investigators Forum - My Grant
Just Got Rejected!! Now What?!? American Heart
Association Scientific Sessions. Dallas, TX. November 1620, 2013.
Spertus JA. Determining What Matters to Patients:
Research Using Patient Centered Outcomes.
American Heart Association Scientific Sessions. Dallas, TX.
November 16-20, 2013.
Spertus JA. Guidelines, Performance Measures
and the Appropriate Use Criteria. 43rd Annual Dr.
Robert D. Conn The Heart Conference. Kansas City, MO.
December 12, 2013.
Spertus JA. Personalized Medicine - Challenges
and Opportunities to Improve Care. University of
London Cardiovascular Grand Rounds. London, England.
December 16, 2013.
Stevens TL. Your Cardiovascular Health. Case
Management Society of America. Overland Park, KS. May
8, 2013.
Stevens TL. Unique Aspects of Women’s
Cardiovascular Health. 6th Annual International
Cardiac Symposium. Cayman Islands Medical & Dental
Society. Cayman Islands. March 14, 2013.
Stevens TL. Promoting Cardiovascular Health.
Cayman Radio. Cayman Islands. March 14, 2013.
Thomas MP, Parzynski C, Curtis J, Seth M, Nallamothu
BK, Chan PS, Spertus JA, Patel MR, Bradley S, Burm
HS. Geographic Regions with Low PCI Utilization
Perform More Appropriate Percutaneous Coronary
Interventions American Heart Association Scientific
Sessions. Dallas, TX. November 16-20, 2013.
Thompson RC, Allam AH, Lombardi GP, Wann LS,
Sutherland ML, Sutherland JD, Soliman MA, Frohlich B,
Mininberg DT, Monge JM, Vallodolid CM, Cox SL, Abd
el-Maksoud G, Badr I, Miyamoto MI, El-Halim Nur ElDin A, Narula J, Finch CE, Thomas GS. Atherosclerosis
Across 4000 Years of Human History: The Horus
Study of Four Ancient Populations. American College
of Cardiology Scientific Sessions. San Francisco, CA.
March 10, 2013.
Thompson RC. The Business of mIBG Imaging,
Looking Back: The Horus Study of Four Ancient
Populations. 18th Annual American Society of Nuclear
Cardiology. Chicago, IL. September 26-29, 2013.
Spertus JA. Engaging the Patient in Decision Making
in Acute Stroke Care. American Heart Association
Scientific Sessions. Dallas, TX. November 16-20, 2013.
Thompson RC. IMPACT Radiological Mummy
Database. Digging into Data Challenge Showcase in
Conjunction with the World Social Sciences Forum.
Montreal, Canada. October 12, 2013.
Spertus JA. Using Outcomes Research and
Personalized Medicine to Improve the Quality
of Care. University of Alberta Cardiovascular Grand
Rounds. Alberta, Canada. December 11, 2013.
Thompson RC. Atherosclerosis: A Modern Malady
or Ancient Illness? 25 Annual Cardiovascular Disease
Symposium. Toledo, OH. December 6, 2013.
Spertus JA. Interpreting Patient-Reported Outcomes
- An Update on the State of the Art. University of
Alberta Research Conference. Alberta, Canada. December
11, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
53
Vigen R, Ho PM, Jones PG, Spertus JA, Arnold SV, Bradley
SM. Hospital-Level Variation in One-Year Mortality
and Angina Following Myocardial Infarction is Not
Explained by In-Hospital Quality of Care in the
TRIUMPH Registry. Quality of Care & Outcomes
Research Scientific Sessions. Baltimore, MD. May 15-17,
2013.
Decker C, Spertus J, Cheng E, Gialde E, Chhatriwalla E,
Summers D, Ayad, M, Saver J, Rymer. Stroke Survivors
and Family Perspectives of Risk/Benefit: Developing
Resolve (Rapid Evaluation For Stroke Outcomes
using Lytics in Vascular Event. International Stroke
Conference Nursing Symposium, Honolulu, HA, February
6. 2013.
Wasfy JH, Strom JB, Rosenfield K, Zai A, Luttrell JM,
Pomerantsev E, Spertus JA, Mauri L, Normand ST,
Yeh RW. Causes of 30-day Readmission Rates after
Percutaneous Coronary Intervention - Lessons from
Direct Chart Review. Quality of Care & Outcomes
Research Scientific Sessions. Baltimore, MD. May 15-17,
2013.
Decker C, Spertus J, Rymer M, Summers D, Gialde
E, Chhatiwalla E. St. Luke’s Hospital, Saver J, UCLA.
Emergency Care/Systems. 2013 International Stroke
Conference, Honolulu, Hawaii, February 6, 2013.
Wasfy JH, Strom JB, Wimmer NJ, Zai A, Luttrell J, Spertus
JA, Normand ST, Mauri L, Yeh RW. Preventability of 30day Readmission after PCI. American Heart Association
Scientific Sessions. Dallas, TX. November 16-20, 2013.
Zhang LQ, Cheranova D, Chaudhardy S, Dai H, Huang
P, Grigoryev D, Heruth D, Li Y, Jones PG, Buchanan
D, Spertus JA, Ye SQ. A New Genetic Biomarker
for Coronary Artery Disease: Nicotinamide
Phosphoribosyltransferase. American Heart Association
Scientific Sessions. Dallas, TX. November 16-20, 2013.
Zhang LQ, Cheranova D, Chaudhardy S, Dai H, Huang
P, Grigoryev D, Heruth D, Li Y, Jones PG, Buchanan
D, Spertus JA, Ye SQ. A New Genetic Biomarker
for Coronary Artery Disease: Nicotinamide
Phosphoribosyltransferase. American Heart Association
Scientific Sessions. Dallas, TX. November 16-20, 2013.
MIDWEST EAR INSTITUTE
Cullen, R. Lewis, K. EAS: Candidate Assessment and
Patient Management. Cochlear EAS Symposium, Las
Vegas, NV, August 2013.
NEUROSCIENCE INSTITUTE
Akhtar N, Holloway W, Martin C, Rymer M, Akhtar E,
Charkravarthy V. Use of Solitaire Retrieval Device
in Wake-up Strokes: Saint Luke’s Neuroscience
Institute Experience. American Society of Neuro
Radiology, San Diego, CA, May, 20, 2013.
Cheng E, Ayad M, Gialde E, Chhatriwalla E, Spertus J,
Rymer M, Summers D, Saver J, Decker C. What Stroke
Survivors and Families Need to Know For Decisionmaking During Acute Ischemic Stroke Care – A
qualitative Research Study. International Stroke
Conference Nursing Symposium, Honolulu, HA, February
6. 2013.
54
Dorssom J, Jones B, Taylor, K. Advanced Practice
Registered Nurses Provide Cost-Effective, Quality
Stroke Care. 2013 International Stroke Conference,
Honolulu, Hawaii, February 6, 2013.
King, S, Jenkins, J. EMS Collaboration to Improve
Field Stroke Recognition. 2013 International Stroke
Conference, Honolulu, Hawaii, February 6, 2013.
King S, and Jenkins J. Hospital and EMS Collaborate to
Improve Field Stroke Recognition. International Stroke
Conference Nursing Symposium, Honolulu, HA, February
6, 2013.
Rymer M. Mild Strokes: To Treat or Not To Treat.
2013 International Stroke Conference, Honolulu, Hawaii,
February 6, 2013.
Spertus J, Cheng E, -UCLA, Gialde E, Chhatriwalla E,
Summers, D, Rymer M, -St. Luke’s Hospital. Stroke
Survivors and Family Perspectives of Risk/Benefit:
Developing RESOLVE (Rapid Evaluation for
Stroke Outcomes Using Lytics in Vascular Event).
2013 International Stroke Conference, Honolulu, Hawaii,
February 6, 2013.
Summers D, Kansas City, MO, Matheson C, Stroudsberg,
PA, Olson, DW, Durham, NC, Shepard, T, Richmond, VA.
Outcome Management: Beyond Process Measures.
International Stroke Conference Nursing Symposium,
Honolulu, HA, February 6, 2013.
Summers D. Comprehensive Overview of Nursing &
Interdisciplinary Care of the Acute Stroke Patient.
It’s Your Time To Peak: Translating Evidence and Excellence
in Stroke Care conference. Shands University of Florida,
Gainesville, FL May 2013.
Summers D. Evidenced Based Nursing: Making a
Difference in Stroke Patient Outcomes. First Health
Moore Regional Hospital Pinehurst, NC, May 2013.
Summers D. Evidenced Based Nursing: Making a
Difference in Stroke Patient Outcomes. 7th Annual
Stroke Conference. Integris Health. Oklahoma City, OK,
February 20-13, 2013.
2013 Research Annual Repor t // Central Office of Research Administration
Summers D. Pre-hospital and ED Acute Stroke
Algorithm; Utilizing Advanced Imaging in Acute
Stroke Treatment; NIHSS with Relation to Neuro
Anatomy. First Annual Penrose Medical Center Stroke
Conference. Colorado Springs, CO, November 2013.
Summers D. Update on Ischemic Stroke Guidelines.
Bethesda North Hospital Grand Rounds. Cincinnati, OH,
July 2013.
NURSING
Cheng E, Ayad M, Gialde E, Chhatriwalla E, Spertus
JA, Rymer M, Summers D, Saver J, Decker C. What
Stroke Survivors and Families Need to Know for
Decision-Making During Acute Ischemic Stroke
Care: A Qualitative Research Study. American Heart
Association/American Stroke Association International
Stroke Conference, Honolulu, Hawaii, February 2013.
Decker C, Chhatriwalla E, Garavalia B, Spertus JA,
Chen E, Gialde E. Differing Perspectives Between
Physicians, Patients and Caregivers on the Value
of an Individualized Estimate of the Benefits Of
Thrombolysis at the Time of Acute Ischemic Stroke:
Designing the Resolve (Rapid Evaluation for Stroke
Outcomes using Lytics in Vascular Event) Decision
Aid. American Heart Association Quality of Care and
Outcomes Research Conference, Washington, DC, May
2013.
Decker C, Spertus JA, Cheng E, Gialde E, Chhatriwalla
E, Summers D, Ayad M, Saver J, Rymer M. Stroke
Survivors and Family Perspectives of Risk/Benefit:
Developing RESOLVE (Rapid Evaluation for
Stroke Outcomes Using Lytics in Vascular Event).
American Heart Association/American Stroke Association
International Stroke Conference, Honolulu, Hawaii,
February 2013.
Dorssom J, Jones B, Taylor K. Advanced Practice
Registered Nurses Provide Cost-Effective, Quality
Stroke Care. International Stroke Conference Nursing
Symposium, Honolulu, Hawaii, February 2013.
Hunt D, Fowler M, Wheeler T. Case Study:
Intraventricular Nicardipine for the Treatment
of Postpartum Cerebral Angiopathy. American
Association of Neuroscience Nursing Conference,
Charlotte North Carolina, March 2013
King S, and Jenkins J. Hospital and EMS Collaborate
to Improve Field Stroke Recognition. International
Stroke Conference Nursing Symposium, Honolulu, Hawaii,
February 2013.
Rao SC, Chhatriwalla AK, Kennedy KF, Decker C, Gialde
E, Spertus JA, Marso SP. Pre-Procedural Estimate of
Individualized Bleeding Risk Impacts Physicians’
Utilization of Bivalirudin during Percutaneous
Coronary Intervention. American College of Cardiology
Scientific Sessions, San Francisco, California, March 2013.
Smolderen KG, Decker C, Garavalia G, Scott KM,
Chhatriwalla EG, Nugent K, Daniel WC, Rivas-Gotz C,
Mena C, Spatz E, Stilp E, Spertus JA. Listening to a
Diversity of Patient Voices to Design a High-Quality
Peripheral Arterial Disease Registry Focusing
on Patient-Centered Outcomes. American Heart
Association Quality of Care and Outcomes Research
Conference, Washington, DC, May 2013.
Summers D, Matheson C, Olson, DW, Shepard, T.
Outcome Management: Beyond Process Measures.
International Stroke Conference Nursing Symposium,
Honolulu, Hawaii, February 2013.
Summers D. Comprehensive Overview of Nursing &
Interdisciplinary Care of the Acute Stroke Patient.
Translating Evidence and Excellence in Stroke Care
Conference, Gainesville, Florida, May 2013.
Summers D. Evidenced Based Nursing: Making a
Difference in Stroke Patient Outcomes. First Health
Moore Regional Hospital, Pinehurst, North Carolina,
May 2013.
Summers D. Evidenced Based Nursing: Making a
Difference in Stroke Patient Outcomes. 7th Annual
Stroke Conference, Oklahoma City, Oklahoma,
February 2013.
Summers D. Pre-hospital and ED Acute Stroke
Algorithm; Utilizing Advanced Imaging in Acute
Stroke Treatment; NIHSS with Relation to Neuro
Anatomy. First Annual Penrose Medical Center Stroke
Conference, Colorado Springs, Colorado, November 2013.
Summers D. Update on Ischemic Stroke Guidelines.
Bethesda North Hospital Grand Rounds, Cincinnati, Ohio,
July 2013.
PHARMACY
Addington L, Oliver K, Patel R, Wilson J. Medication
Evaluation Utilization of Insulin. American Society
of Health-System Pharmacists Midyear Clinical Meeting,
Orlando, Florida, December 2013.
Bennett N. Residencies. Student Forum, Student Society
of Health-System Pharmacists, Drake University, Des
Moines, Iowa, April 2013.
2013 Research Annual Repor t // Central Office of Research Administration
55
Burton S, Galen K. Evaluation of the Effect of
Pharmacist Education on Acute Myocardial
Infarction Readmission Rates. Midwest Pharmacy
Resident’s Conference, Omaha, Nebraska, May 2013.
Little J. Real World Implications for Pharmacy
Practice Model Change. Student Society of HealthSystem Pharmacists, Creighton University School of
Pharmacy, Omaha, Nebraska, November 2013.
Burton S, Galen K, Blunck K. Evaluation of the Effect
of Pharmacist Education on Acute Myocardial
Infarction Readmission Rates. Missouri Society of
Health-System Pharmacists Annual Meeting, St. Louis,
Missouri, April 2013.
Little J. Conflict Resolution for New Practitioners.
American Society of Health-System Pharmacists Midyear
Clinical Meeting, Orlando, Florida, December 2013.
Coleman A, Blunck K, Hayes C. Tolvaptan Use at a
Tertiary Medical Center: Evaluating Appropriate
Use, Safety, Efficacy and Cost. American Society of
Health-System Pharmacists Midyear Clinical Meeting,
Orlando, Florida, December 2013.
Douglass L, Repp K, Lamar J, Woods M. Hypoglycemia
in Patients Admitted on Home Antidiabetic
Regimen. American Society of Health-System
Pharmacists Midyear Clinical Meeting, Orlando, Florida,
December 2013.
Eklund J, Abi B, Bliss K, Repp K, Woods M. Effect of
Adherence to Weight-Based Heparin Protocol on
Achieving Therapeutic Anti-Xa Levels. American
Society of Health-System Pharmacists Midyear Clinical
Meeting, Orlando, Florida, December 2013.
Huedepohl E, Woods M. Impact of Individualized
Feedback on Medication Barcode Scan Rates.
Missouri Society of Health-System Pharmacists Annual
Meeting, St. Louis, Missouri, April 2013.
Huedepohl E. Impact of Individualized Feedback on
Medication Barcode Scan Rates. Midwest Pharmacy
Resident’s Conference, Omaha, Nebraska, May 2014.
Huninghake C, Blunck J, Milligan B, Woods M.
Evaluation of Four-Factor Prothrombin Complex
Concentrate in the Management of Warfarin-related
Intracranial Hemorrhage. American Society of HealthSystem Pharmacists Midyear Clinical Meeting, Orlando,
Florida, December 2013.
Kelley P. Impact of Procalcitonin-Guided Antibiotic
Therapy in Pneumonia and COPD Exacerbations in
an Academic Community Hospital Setting. Midwest
Pharmacy Resident’s Conference, Omaha, Nebraska,
May 2013.
Kelley P, Bennett N. Impact of Procalcitonin-Guided
Antibiotic Therapy in Pneumonia and COPD
Exacerbations in an Academic Community Hospital
Setting. Missouri Society of Health-System Pharmacists
Annual Meeting, St. Louis, Missouri, April 2013.
56
Martin K, Massey L, Mebel E, Ortega M. Smooth
Transitions: Aligning Expectations of the First 90
Days. American Society of Health-System Pharmacists
Midyear Clinical Meeting, Orlando, Florida, December
2013.
McLouth E, Schnabel L. Evaluating a Maximum
Osmolarity of 1100 mOsm/L for Extravasation in
Neonates Receiving Total Parenteral Nutrition – A
Retrospective Chart Review. Missouri Society of
Health-System Pharmacists Annual Meeting, St. Louis,
Missouri, April 2013.
Miller B. Effects of Order Set Use on the Treatment
of Clostridium difficile: A Best Practice Assessment.
Midwest Pharmacy Resident’s Conference, Omaha,
Nebraska, May 2013.
Miller B, Berry T, Bennett N. Effects of Order Set Use
on the Treatment of Clostridium difficile: A Best
Practice Assessment. Kansas Council of Health-System
Pharmacists Annual Meeting, Wichita, Kansas, April 2013.
Nguyen V, Bennett N, Day K, House J, Woods M. Analysis
of Subjective Procalcitonin Use in a Tertiary
Healthcare System. American Society of Health-System
Pharmacists Midyear Clinical Meeting, Orlando, Florida,
December 2013.
Nguyen T, Woods M, Bennett N. Evaluation of
Antimicrobial Utilization on Bacterial Susceptibility
Patterns Within Saint Luke’s Health System.
American Society of Health-System Pharmacists Midyear
Clinical Meeting, Orlando, Florida, December 2013.
O’Dell K, Anderson R, Ploetz J. Utilization of
Prophylactic Enoxaparin Before and After
Modification of the VenousThromboembolism (VTE)
Order Set and the Plausibility of Pharmacist Driven
VTE Discontinuation Criteria. Missouri Society of
Health-System Pharmacists Annual Meeting, St. Louis,
Missouri, April 2013.
Pounders A. Evaluation of a Pharmacist-Driven
Protocol for the Discontinuation of Inappropriate
Stress Ulcer Prophylaxis. Midwest Pharmacy Resident’s
Conference, Omaha, Nebraska, May 2013.
2013 Research Annual Repor t // Central Office of Research Administration
Pounders A, Blunck J, Ploetz J. Evaluation of a
Pharmacist-Driven Protocol for the Discontinuation
of Inappropriate Stress Ulcer Prophylaxis. Missouri
Society of Health-System Pharmacists Annual Meeting, St.
Louis, Missouri, April 2013.
Pummel S, Aldridge S. Evaluation of Intravenous Iron
Sucrose Prescribing After the Implementation of
a Mandatory Order Set Across a Four Hospital
System. Kansas Council of Health-System Pharmacists
Annual Meeting, Wichita, Kansas, April 2013.
Pummel S. Evaluation of Intravenous Iron Sucrose
Prescribing After the Implementation of a
Mandatory Order Set Across a Four Hospital
System. Midwest Pharmacy Residents Conference,
Omaha, Nebraska, May 2013.
Smith B, Bennett N. Improvement of Empiric
Antibiotic Selection Through Annual Drug-Bug
Mismatch Analysis. American Society of Health-System
Pharmacists Midyear Clinical Meeting, Orlando, Florida,
December 2013.
RADIOLOGY
Al Qaisi, Walker CM, Cox CW, Kanne JP, Chung JH.
Role of Bronchoalveolar Lavage in the Diagnosis
ofInterstitial Lung Diseases. Poster at AUR, April 2013.
Andresen KJ. Genitourinary: Kidney, Case Based
Imaging Review Course. American Roentgen Ray Society
Annual Meeting, Washington DC, April 2013.
Benson RE, Rosado-de-Christenson ML, MartinezJimenez S, Kunin JR, Watson K, Pettavel PP. Spectrum
of Thoracic Neuroendocrine Proliferations and
Neoplasms: Carcinoid, Carcinoid Tumorlets,
DIPNECH, & Carcinoid Syndrome. Third World
Congress of Thoracic Imaging, Seoul, South Korea, June
8-11, 2013.
Bhatt M, Adler K, Borsa JJ, Cho K, Saucier N, Wible BC.
Sacroplasty: “A Remedy for Pains in the Butt?”
Radiological Society of North American 99th Scientific
Assembly and Annual Meeting, Chicago, IL. December
2013. Certificate of Merit Award
Borsa JJ. BRTO Lecture, Society of Abdominal Radiology
Annual Meeting, Maui, HI, Feb 24 – March 1, 2013
Desouches S, Sanchez JL, Stull MA. Crystalline
Disease: The Good, the Bad, the Ugly, and the
Imposters. Association of University Radiologists 61st
Annual Meeting. Los Angeles, CA, April 9 -12, 2013.
Franquet T, Rosado-de-Christenson ML, Kanne
JP, Marchiori E, Martínez-Jiménez S, Gimenez A.
Hemorrhagic And Vascular Complications In Lung
Infections: High-Resolution CT And Pathologic
Findings. Radiological Society of North American 99th
Scientific Assembly and Annual Meeting, Chicago, IL.
November – December 2013. Magna Cum Laude Award
Kunin J, Martinez-Jimenez S, Rosado-de-Christenson ML,
Walker CM. High Resolution Computed Tomography
Of Hemorrhagic Disorders. Radiological Society of
North American 99th Scientific Assembly and Annual
Meeting, Chicago, IL. December 2013.
Lerner DJ, Wible BC, Gooden C, Pelletier S, Randall
HB. A Novel Procedure For Managing Excluded
Segmental Postoperative Bile Duct Leak. Americas
Hepato-Pancreato-Biliary Association National
Conference. Miami, FL. Feb 2013.
Martínez-Jiménez S. Non-Surgical Extracardiac
Vascular Shunts Of Thorax. Visiting Lecturer,
University of Virginia. Charlottesville, VA. 15 March 2013.
Martínez-Jiménez S. Ascending Thoracic Aorta:
Postoperative CT Evaluation. Visiting Lecturer,
University of Virginia, Radiology - Grounds Rounds.
Charlottesville, VA. 15 March 2013.
Martínez-Jiménez S. Idiopathic Interstitial
Pneumonia. Asociacion Colombiana de Radiologia Zonal
Santander. 20 March 2013.
Martinez-Jimenez S, Rosado-de-Christenson ML,
Walker CM, Kunin JR. Thoracic Metastases From
Gynecological Neoplasms: How They Differ From
Other Metastases, Specific Patterns Of Spread, And
Pitfalls In Imaging Interpretation. Radiological Society
of North American 98th Scientific Assembly and Annual
Meeting, Chicago, IL. December 2013. Certificate of Merit
Laude Award
Peterson, PG Walker CM, Imanzadeh A, et al. Genetic
mutations in NSCLC: Imaging patterns and
implications. Electronic exhibit at ARRS, April 2013.
Rosado de Christenson ML. Nodulo Pulmonar
Solitario, Colegio Interamericano de Radiología, Cancún,
Mexico, May 2013.
Rosado de Christenson ML. Sarcoidosis, Colegio
Interamericano de Radiología, Cancún, Mexico, May 2013.
Rosado de Christenson ML. Tuberculosis, Colegio
Interamericano de Radiología, Cancún, Mexico, May 2013.
Rosado de Christenson ML. Enfermedades Pleurales
No Neoplasicas, Colegio Interamericano de Radiología,
Cancún, Mexico, May 2013.
Rosado de Christenson ML. Enfermedades Pleurales
Neoplasicas, Colegio Interamericano de Radiología,
Cancún, Mexico, May 2013.
2013 Research Annual Repor t // Central Office of Research Administration
57
Rosado de Christenson ML, New Concepts and
Imaging of Thymic Malignancies, World Congress of
Thoracic Imaging, Third World Congress, Seoul, Korea,
June, 2013.
Rosado-de-Christenson ML, Martinez-Jimenez S,
Walker CM, Kunin JR, Wible BC. Bronchial Arteries:
Anatomy, Function, Hypertrophy and Interventions.
Radiological Society of North American 99th Scientific
Assembly and Annual Meeting, Chicago, IL. December
2013. Certificate of Merit Award
Walker CM, Peterson PG, Abbott GF, et al. Imaging
Findings of Pulmonary Infection: Classic Signs.
Electronic exhibit at ARRS, April 2013.
SURGERY
Friedell ML. Transitioning from Medical School to
Surgical Residency. Association of Program Directors in
Surgery Panel Session, Moderator, Orlando, FL, April 26
2013.
Friedell ML. Contemporary Management of Celiac
Artery Compression Syndrome, Poster Presentation,
Society for Clinical Vascular Surgery, Miami Beach, FL
March 14-16 2013.
Friedell, ML Perceptions of Graduating General
Surgery Chief Residents: Are They Confident in
Their Training? Southern Surgical Association, Podium
Presentation, Hot Springs, VA, December 3, 2013.
WOMEN AND CHILDREN
Jodicke C, Singh P, Orth T, Bennett T, Mundy D, Maulik
Dev. Correlation Between Prenatal and Postnatal
Diagnosis of Congenital Heart Disease in a
Quaternary Perinatal Center. Central Association of
Obstetricians and Gynecologists Annual Meeting, Napa,
CA October 16-19, 2013.
Maulik, Dev. Managing Fetal Growth Restriction:
Current Challenges, Advances in fetal functional
Echocardiography-An Update. XI World Congress of
Perinatal Medicine, Moscow, June 2013.
Maulik, Dev. Current Approaches to Managing
Premature Rupture of Membranes. XI World
Congress of Perinatal Medicine, Moscow, June 2013.
Maulik, Dev. Current Approaches to Managing
Premature Rupture of Membranes. XI World
Congress of Perinatal Medicine, Moscow, June 2013.
Singh P, Jodicke C, Swanson T, Maulik Dev. Thoracic
Ganglioneuromas Resulting in Hudrops Fetalis.
Central Association of Obstetricians and Gynecologists
Annual Meeting, Napa, CA October 16-19, 2013.
58
2013 Research Annual Repor t // Central Office of Research Administration
Federally Funded
Research Project Details
Dr. Chan Project, pages 6 and 9
This project is funded 100 percent by research federal grant
dollars and the total amount is $618,105. FREEDOM Trial, page 9
This project was funded 100 percent by research federal grant
dollars and the total amount was $1,309,678.
CORAL Trial, page 9
This project is funded 100 percent by research federal grant
dollars and the total amount is $1,500,000. Dr. Spertus and Dr. Decker, Multivariable Risk Models,
page 8
This project is funded 100 percent by research federal grant
dollars and the total amount is $4,173,058.
CIRT Project, page 10
This project is funded 100 percent by research federal grant
dollars and the total amount is $765,000.
Stanford University, Intra-arterial Stroke Treatment
Project, page 12
This project is funded 100 percent by research federal grant
dollars and the total amount is $65,386.
The Johns Hopkins Medical Institutions, Hemorrhagic
Stroke Study, page 12
This project is funded 100 percent by research federal grant
dollars and the total amount is $21,572.
ATTRACT Study, page 14
This project is funded 100 percent by research federal grant
dollars and the total amount is $8,500.
2013 Research Annual Repor t // Central Office of Research Administration
59
2013 Board Medical Staff Research Committee
Saint Luke’s Health System
Committee Members:
John Phillips, Chair
Donald Campbell, M.D.
David Cohen, M.D., Co-Chair
Alan Forker, M.D.
Rakesh Gaur, M.D.
Kathy Harms, Ph.D.
Dean L. Hubbard, Ph.D.
David T. Hunt
Darren Lovick, M.D.
Timothy Pluard, M.D.
David Powell
Julie Quirin, CEO, Saint Luke’s Hospital
Henry Randall, M.D.
Marilyn Rymer, M.D.
John Spertus, M.D.
Karen Williams, Ph.D.
John Yeast, M.D.
Ex officio Members:
Jacque Carpenter – Nursing Research
Mike Coffman – Saint Luke’s Mid America Heart Institute
Marilyn Horn – Institutional Review Board
Krista Ludwikoski – Office of General Counsel
Ellen McDowell – Central Office of Research Administration
Anne Strassfeld – Office of General Counsel
Thomas W. Wagstaff, Chairman, Saint Luke’s Health System
Julie Weiss – Saint Luke’s Cancer Institute
Veronica Koontz, Central Office of Research Administration
Recorder of Minutes
Contact us
Central Office of Research Administration
Saint Luke’s Hospital of Kansas City
4401 Wornall Road
Kansas City, MO 64111
816-932-8161
saintlukeshealthsystem.org
2014-1022