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https://www.embase.com
㈜바이텍켐스 신혜리 대리
[email protected]
www.bitekchems.com
EMBASE TRAINING
Copyright© 2014 by BITEK CHEMS Inc.
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BITEK CHEMS Products Line(1)
Online
Journals
Databases
Informatics
Molecular
Modeling
Predictions
Others
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BITEK CHEMS Products Line(2)
Target
Finding
Lead
Compounds
Hit
Identification
Launch
Market
Pre-Clinical
Drug
Candidate
Clinical
E-Notebook
Spotfire
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•
•
•
•
•
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• EMBASE
REAXYS
• PHARMAPENDIUM
PHARMAPENDIUM
ArticleChoice
PerkinElmer Informatics
Gaussian, Scigress, Hyperchem
Leadscope, StarDrop
What is EMBASE?
• 1947년부터 현재까지의 biomedical 문헌을 다룬 데이터베이스
(1947-1973년까지는 EMBASE Classic 별도)
• Pharmacology, Toxicology, Clinical Medicine을 포함한
폭넓은 biomedical 분야의 8,400 종 저널의 Record 수록
• 임상 연구의 진행 상황 모니터링 및 약물 안전성, 부작용, 치료법 등
정보 이용 시 반드시 필요한 데이터베이스
• 생명과학 분야 용어색인자료인 Emtree를 통한 종합적인 검색
• 의학적 판단 시 객관성, 투명성을 재고할 수 있는 방법으로 모색된
Evidence Based Medicine(EBM) 정보 제공
• 문헌 검색 시, 미국 NLM이 제시한 COSI 모델 중
가장 효과적인 Core 검색 자료원으로 EMBASE 제시
Copyright© 2014 by BITEK CHEMS Inc.
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History of EMBASE
Excerpta Medica Abstract Journals (1947~1948)
• 15 abstract journal titles, growing to more than 40
• Abstract journals (not citation indexes)
• Controlled indexing (later branded as “Emtree”)
EMBASE database online(1979)
• First commercial offering via Lockheed Dialog
• Now available on multiple online platforms
EMBASE becomes Embase (2009)
• Additional MEDLINE content licensed from NLM
• Online availability extended back to 1947
• Original abstracts (1947-1974) become
available as Embase Classic
Copyright© 2014 by BITEK CHEMS Inc.
All rights reserved.
EMBASE is for…
Copyright© 2014 by BITEK CHEMS Inc.
All rights reserved.
EMBASE is about comprehensive searching
...by including literature and information
resources in a timely manner
...by reading full-text to identify
drugs, diseases, adverse affects,
clinical trials, drug trade names etc.
Conference
proceedings
Scientific
Journals
In Press
(unpublished)
We make sure you don’t
miss any
biomedical literature
Deep indexing using own
taxonomy (EMTREE)
They only close
alternative is reading
all the articles
Very powerful
Search Environment
Good precision and
recall balance
...by enabling advanced search filters to
drill down a comprehensive search to
a relevant and manageable record set
...by allowing users to automate
searching and result management
Copyright© 2014 by BITEK CHEMS Inc.
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Automation and
documentation
EMBASE Contents
Fully indexed:
8,400 journals
Unique to EMBASE:
2,700 journals
Over 5,000 records added/day
1,300,000 record added/year
EMBASE Classic:
Digitally scanned and
re-indexed, 1947-1973
Copyright© 2014 by BITEK CHEMS Inc.
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EMBASE Scope & Coverage
Pharmacology & Toxicology 12%
General Clinical Medicine 11%
Genetics, Biochemistry & Molecular Biology 10%
Neurology & Behavioral Medicine 8%
Microbiology & Infectious Disease 7%
Cardiology & Hematology 6%
Psychiatry & Mental Health 6%
Oncology 5%
Healthcare Policy & Management 4%
Allergy & Immunology 4%
Pediatrics 4%
Endocrinology & Metabolism 3%
Obstetrics & Gynecology 3%
Biomedical Engineering & Medical Devices 3%
Anesthesiology & Intensive Care 3%
Gastroenterology 2%
Respiratory Medicine 2%
Nephrology & Urology 2%
Dermatology 2%
Copyright© 2014 by BITEK CHEMS Inc.
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Other topics 28%
Including public health, basic
biomedical science and topic
s included from MEDLINE
What is Emtree?
Emtree is a Life Science Thesaurus.
A controlled vocabulary for Biomedicine and related Life Sciences
 Easy to Search
• 60,000 개 이상의 우선어와 270,000 개 이상의 동의어
 Inclusive Terminology
• MeSH의 2배 이상 용어 포함 (모든 MeSH 용어 포함)
• 22,000 개 이상의 CAS registry number
 Comprehensive Drug & Disease Searching
• Chemical names, trade names, laboratory/research codes,
30,000 개 이상의 generic drugs 과 chemicals (FDA, EMEA,WHO)
• 78 개 subheadings
(64 개 drug subheadings 과 14개 disease subheadings)
• Study type(Randomized Controlled Trial, Systematic Review,
Diagnostic Test Accuracy Study 등 포함)에 대한 40개 check tags
What is Emtree?
Synonyms
Keyword에 대한
계층별 확인
Copyright© 2014 by BITEK CHEMS Inc.
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Emtree-Drug Subheading
Emtree를 통한 article에
인덱스된 Drug term의
Key Subheading 확인
Copyright© 2014 by BITEK CHEMS Inc.
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Emtree-Disease Subheading
Emtree를 통한 article에
인덱스된 Disease term의
Key Subheading 확인
Copyright© 2014 by BITEK CHEMS Inc.
All rights reserved.
The power of indexing
Database
Thesaurus
EMBASE
Emtree
'digoxin'/exp AND 'anti bacterial agents'/exp
9, 466
PubMed
MeSH
(Digoxin[MeSH Terms]) AND Anti-Bacterial
Agents[MeSH Terms]
140
Copyright© 2014 by BITEK CHEMS Inc.
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Search
Result
Medicine Without Evidence
Johns Hopkins’ Tragedy: Could a death have been prevented?
Source: http://newsbreaks.infotoday.com/nbreader.asp?ArticleID=17534
Copyright© 2014 by BITEK CHEMS Inc.
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What is EBM?
Systematic Review & Meta-Analysis
Randomized Controlled Trial
Quality of
evidence
Cohort studies
Case Controlled Studies
Case Series/Report
Background Information/
Expert Opinion
Copyright© 2014 by BITEK CHEMS Inc.
All rights reserved.
Filtered
Information
Unfiltered
Information
EBM terms in EMBASE
Advanced Search
Emtree
Copyright© 2014 by BITEK CHEMS Inc.
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Search Type
• Search
- Quick Search
- Advanced Search
- Drug Search
- Disease Search
- Device Search
- Article Search
• Browse
- Emtree Search
- Journals Search
- Authors Search
Copyright© 2014 by BITEK CHEMS Inc.
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Case Study-Drug & diseases
Evaluate the evidence that children
treated for depression using
SSRIs(Serotonin Reuptake Inhibitors)
are at increased risk of suicide.
Copyright© 2014 by BITEK CHEMS Inc.
All rights reserved.
Case Study-Diagnostic tests
How accurately does HPV testing
predict cervical cancer in adult women?
Copyright© 2014 by BITEK CHEMS Inc.
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Case Study-Medical devices
What are the pro’s and con’s for
metal-on-metal hip implants vs
other types in different patient groups?
Copyright© 2014 by BITEK CHEMS Inc.
All rights reserved.
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㈜ 바이텍켐스
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