MAC 4th MUNICH AORTIC & CAROTID CONFERENCE 2014 where doctors meet science www.mac-conference.com VENUE Klinikum rechts der Isar Munich, Germany December 5th – 6th, 2014 CHAIRMAN (Technische Universität München, TUM) n Hans-Henning Eckstein CO-CHAIRMEN (Technische Universität München, TUM) n n n n n n Rüdiger Lange Markus Schwaiger Holger Poppert Alma Zernecke Wolfgang Wall Michael Gee AAA-Screening Symposium in cooperation with Thursday, December 4th, 2014 TABLE OF CONTENT n WELCOME ............................................................................................................... 4 – 5 n GENERAL INFORMATION ....................................................................................... 6 – 7 n AAA-SCREENING SYMPOSIUM ............................................................................ 8 – 11 n PROGRAM Program at a Glance ........................................................................................... 12 – 14 Program Friday, December 5th ........................................................................... 16 – 23 Program Saturday, December 6th ....................................................................... 24 – 27 n WORKSHOPS ............................................ ................................................................. 29 n POSTERSESSIONS AND ORAL PRESENTATIONS ................................................ 30 – 31 n KEYNOTE LECTURES ........................................................................................... 32 – 33 n FACULTY .............................................................................................................. 35 – 38 n SPONSORS .................................................................................................................. 39 www.mac-conference.com WELCOME WELCOME Dear colleagues, Hans-Henning Eckstein Klinikum rechts der Isar der Technischen Universität München Department for Vascular and Endovascular Surgery Rüdiger Lange Deutsches Herzzentrum der Technischen Universität München Department for Cardiovascular Surgery Markus Schwaiger Klinikum rechts der Isar der Technischen Universität München Department for Nuclear Medicine Holger Poppert Klinikum rechts der Isar der Technischen Universität München Department for Neurology 4 It is thrilling how new diagnostic and therapeutic methods for vascular diseases are showing up almost every week. However, to assess this progress correctly, thorough understanding of the underlying etiology and the interaction between blood flow and the atherosclerotic or aneurysmatic arteries is mandatory. This goal can only be achieved by mutual exchange between vascular clinicians and fundamental/translational researchers. Thereby, the 4th Munich Aortic & Carotid Conference (MAC) aims to connect the frequently diverging worlds of fundamental science, clinical research and clinical practice. We are very happy to invite you to the 4th MAC on the first December weekend 2014. Again, we will focus on aortic and carotid issues; a joint meeting with topics ranging from basic science and engineering to clinical issues and patient care. In detail, the aortic sessions will include ascending aortic and aortic arch issues, current indications for TEVAR in acute aortic dissections and the management of type II endoleaks after EVAR. Further special sessions will address the current role of simulation techniques in modeling and understanding of vascular disease. Since the technical progress in hybrid ORs is extremely rapid, we will again discuss options on how to optimize the workflow by using imaging fusion techniques and endovascular navigation. The carotid sessions will feature topics, such as clinical trials, the optimal timing of invasive treatment in carotid-related cerebral ischemia, the assessment of asymptomatic carotid stenoses, and carotid plaque vulnerability. Many attendees of MAC favor to attend all main carotid and aortic sessions. To overcome the conflict of parallel sessions, Friday, December 5th will be reserved for the main aortic sessions and Saturday, December 6th, for the main carotid sessions respectively. Parallel sessions will only be scheduled for special issues. Again, we are very proud to present a world-class faculty of national and international experts in clinical and translational vascular research. Our speakers are very experienced presenters and all of them are keen to exchange their ideas with the audience. We are fully aware that in-depth discussion following the oral presentation is sometimes even more interesting for the audience than the lecture itself. Therefore, sufficient time is scheduled for extensive discussions with the audience. For the first time, scientific abstracts were submitted. Out of almost 40 submissions we selected seven abstracts for oral presentation and included them into the scientific program. Further 27 submitters were chosen to present their abstracts as posters. The best presentations will be awarded EUR 500.00! The 4th MAC 2014 is a platform where clinical researchers from vascular/cardiovascular surgery, neurology, cardiology, angiology and anesthesiology can meet radiologists and imaging specialists, vascular biologists and basic researchers in a very friendly and relaxed atmosphere. Do not miss the opportunity to share the latest insights into the world of academic vascular research, represented by our world-class national and international faculty! The 4th MAC will provide you with late-breaking news and cutting-edge approaches in vascular medicine and will enable you to be part of the thrilling progress of improving the diagnosis and treatment of carotid and aortic diseases. Alma Zernecke Universität Würzburg Institute for Clinical Biochemistry and Pathobiochemistry Wolfgang Wall Technische Universität München Institute for Computational Mechanics Michael Gee Technische Universität München Mechanics and High Performance Computing Group The 4th MAC 2014 is being held under the patronage of the German Vascular Society (DGG) and the VASCULAR INTERNATIONAL foundation. We look forward to welcoming you in Munich. Hans-Henning Eckstein Rüdiger Lange Markus Schwaiger Holger Poppert Alma Zernecke Wolfgang Wall Michael Gee 5 GENERAL INFORMATION GENERAL INFORMATION n DATE Friday and Saturday December 5th – 6th, 2014 n CERTIFICATION An application has been made to the Bavarian Medical Association for CME accreditation of this event. n VENUE Klinikum rechts der Isar (MRI) der Technischen Universität München (TUM) Ismaninger Strasse 22 | 81675 Munich | Germany n LANGUAGE The official language of this meeting is English. There will be no simultaneous translations. n CONGRESS SECRETARIAT Kathrin Berkenkamp Kathrin Ernstberger Dr. Eva Knipfer Dr. Heidi Söllner n REGISTRATION FEE Department for Vascular and Endovascular Surgery Klinikum rechts der Isar der Technischen Universität München Ismaninger Strasse 22 81675 Munich | Germany Phone: +49 (0)89 41 40 21 67 Fax: +49 (0)89 41 40 48 61 E-Mail: [email protected] n CONGRESS ORGANISATION Full Registration Day Registration Dec. 5th Dec. 6th Physicians EUR 300.00 EUR 200.00 EUR 200.00 Physicians in training EUR 200.00 EUR 150.00 EUR 150.00 Fellows, Nurses and MTs EUR 100.00 EUR 50.00 EUR 50.00 Students (written confirmation required) free of charge Food and Beverages are included in the registration fee. For registration please use the website www.mac-conference.com or the attached registration form. n GET-TOGETHER Friday, December 5th, 2014 | 19:30 EUR 50.00 per person KelCon GmbH Franziska Klug Liebigstrasse 16 | 63500 Seligenstadt | Germany Phone: +49 (0)6182 94 666 16 Fax: +49 (0)6182 94 666 44 E-Mail: [email protected] www.kelcon.de n TRAVEL MANAGEMENT Our travel management is looking forward to assisting you with the organisation and booking of your journey. Any program changes will be published on our website on a regular basis. For detailed information visit www.mac-conference.com Phone: +49 (0)6182 94 666 22 E-Mail: [email protected] 6 7 in Kooperation mit in cooperation with in Kooperation mit in cooperation with Hörsaal C Münchner AAA-Screening Symposium th In Kooperation mit der 4 Munich Aortic & Carotid Conference (MAC) und der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin (DGG) In cooperation with the 4th Munich Aortic & Carotid Conference (MAC) and the German Vascular Society (DGG) 10:30-11:00 Einschreiben / Registration 11:00-11:05 Begrüßung / Welcome H.-H. Eckstein, Munich, Germany 11:05-12:35 Ultraschall-Screening des abdominalen Aortenaneurysmas (AAA) – Studien, Evidenz, internationale Programme Ultrasound screening of abdominal aortic aneurysms (AAA) – trials, evidence, international implementation Vorsitz / Chairs: Donnerstag, 4. Dezember 2014, 11:00–17:00 Uhr Thursday, December 4th, 2014, 11:00 am until 5:00 pm S. Teupen, Berlin, Germany; G. Torsello, Münster, Germany B-Bild-Sonographie der abdominalen Aorta: Technik, Qualifikation und Dokumentation – Standards der Deutschen Gesellschaft für Ultraschall in der Medizin (DEGUM) B-Mode-Sonography of the abdominal aorta – standards of the German Society for Ultrasound in Medicine Deutsch / Englisch mit Simultanübersetzung · Eintritt frei German / English with simultaneous translation · Free entrance Organisation und Leitung/Chairs: W. Schäberle, Göppingen, Germany • Hans-Henning Eckstein, Chief Editor GEFAESSCHIRURGIE Ehemaliger Präsident der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin (DGG) Past-President of the German Vascular Society (DGG) Behandlung des AAA in Deutschland – AAA-Register der Deutschen Gesellschaft für Gefäßchirurgie und Daten des Statistischen Bundesamtes 2000 bis 2013 Treatment of AAA in Germany – the AAA Registry of the German Vascular Society and data of the Federal Bureau of Statistics • Sebastian Debus Präsident der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin (DGG) President of the German Vascular Society (DGG) M. Trenner, London / Munich, United Kingdom / Germany Ultraschall-Screening – aktuelle Studienlage AAA screening trials • Giovanni Torsello Vizepräsident der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin (DGG) Vice President of the German Vascular Society (DGG) H.-H. Eckstein, Munich, Germany Risikofaktoren für die Entstehung eines AAA oder: welche Population soll gescreent werden? Risk factors for AAA or: who should be screened? • Susanne Teupen Stabsstelle Patientenbeteiligung beim Gemeinsamen Bundesausschuss (G-BA) Subcommittee on patient involvement, Federal Joint Committee (G-BA) I. Flessenkämper, Berlin, Germany Ethische Aspekte von Screening Untersuchungen Ethical aspects of screening I. Mühlhauser, Hamburg, Germany Zusammenfassung / Summary www.mac-conference.com 8 S. Teupen, Berlin, Germany; G. Torsello, Münster, Germany 12:35-13:20 M I T TA G S PA U S E / L U N C H 9 in Kooperation mit in cooperation with 13:20-14:40 in Kooperation mit in cooperation with Sicht der Kassenärztlichen Bundesvereinigung (KBV) AAA screening programs in Europe and overseas View of the National Association of Statutory Health Insurance Physicians S. Steiner, Berlin, Germany (tbc) Vorsitz / Chairs: H.-H. Eckstein, Munich, Germany; I. Flessenkämper, Berlin, Germany Sicht der deutschen Krankenhausgesellschaft View of the German Hospital Federation AAA screening in the United States N. Schlottmann, Berlin, Germany (tbc) F. Mussa, New York, USA Stand des Projektes AAA Screening beim G-BA The NHS AAA screening program in the United Kingdom Current status of the project „AAA screening“ at the Federal Joint Commitee (G-BA) J. Earnshaw, Gloucestershire, United Kingdom S. Teupen, Berlin, Germany AAA screening in the context of a changing epidemiology, which intervals are reasonable and should subaneurysmatic aortas be rescreened? – the Swedish AAA screening program Zusammenfassung / Summary S. Debus, Hamburg; S. Teupen, Berlin, Germany M. Björck, Uppsala, Sweden AAA screening trials in Denmark H. Sillesen, Copenhagen, Denmark 16:55-17:00 VERABSCHIEDUNG/FAREWELL H.-H. Eckstein, Munich, Germany AAA screening in Poland A. Jawien, Bydgoszcz, Poland, President ESVS The prevalence of AAA and PAD amongst 4 million screened US adults and the importance of smoking as a risk factor R. Bulbulia, Oxford, United Kingdom 14:40-15:10 K A F F E E PA U S E / C O F F E E B R E A K 15:10-16:55 Umsetzung eines AAA-Screening-Programm in Deutschland How to implement a national AAA screening program in Germany Vorsitz / Chairs: S. Debus, Hamburg; U. Hoffmann, Munich; S. Teupen, Berlin, Germany Sicht der Deutschen Gesellschaft für Angiologie (DGA) View of the German Society of Angiology U. Hoffmann, Munich, Germany Sicht der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin (DGG) View of the German Vascular Society S. Debus, Hamburg, Germany 10 REFERENTEN / FACULTY n Martin Björck, Uppsala, Sweden n Richard Bulbulia, Oxford, United Kingdom n Jonothan Earnshaw, Gloucestershire, United Kingdom n Ingo Flessenkämper, Berlin, Germany n Ulrich Hoffmann, Munich, Germany n Arkadiusz Jawien, Bydgoszcz, Poland n Ingrid Mühlhauser, Hamburg, Germany n Firas Mussa, New York, USA n Wilhelm Schäberle, Göppingen, Germany n Nicole Schlottmann, Berlin, Germany (tbc) n Henrik Sillesen, Copenhagen, Denmark n Sybille Steiner, Berlin, Germany (tbc) n Matthias Trenner, London / Munich, United Kingdom / Germany 11 PROGRAM AT A GLANCE Friday, December 5 LECTURE HALL B Aortic issues 09:00– 10:40 10:40– 11:05 Keynote lecture Carotid issues 11:05– 12:35 MAC 1 Endovascular solutions for the ascending aorta and arch aneurysms LECTURE HALL C 09:00– MCC 1 10:40 Advances in carotid plaque biology MAC 2 11:05– 12:30 MCC 2 Carotid ultrasound beyond the degree of stenosis 12:55– 14:00 Keynote lecture 14:00– 15:15 LUNCH BREAK IN THE EXHIBITION AREA MAC 3 Aortic emergencies II: ruptured AAA 16:00– 16:30 11:00– 12:35 MAC 6 Aortic emergencies III: the infected aorta LECTURE HALL B 09:00– 10:30 MCC 4 The future of Carotid Artery Stenting (CAS) COFFEE BREAK IN THE EXHIBITION AREA MAC 7 Perioperative imaging, fusion and navigation 11:00– 12:35 MCC 5 Asymptomatic carotid disease LECTURE HALL C 14:00– 15:15 Keynote lecture F. J. Veith, New York, USA PAVILLON MCC 3 Functional imaging of atherosclerotic lesions LECTURE HALL B 15:20– 16:00 09:00– 10:30 12:40– 13:00 H. J. Safi, Houston, USA LECTURE HALL B LECTURE HALL C LECTURE HALL B LECTURE HALL B 12:35– 12:55 Saturday, December 6th 10:30– 11:00 COFFEE BREAK IN THE EXHIBITION AREA Aortic emergencies I: acute Type B Aortic Dissection (TBAD) PROGRAM AT A GLANCE th 13:00– 14:00 Poster Session II (No. 15-27) 13:00– 14:00 LUNCH BREAK IN THE EXHIBITION AREA LECTURE HALL B Keynote lectures MCC 6 V. Ntziachristos, Munich, Germany P. Lawrence, Los Angeles, USA 14:00– 15:45 Carotid trials and the impact of TIME in symptomatic patients COFFEE BREAK IN THE EXHIBITION AREA 15:45 FAREWELL PAVILLON 16:00– 17:30 Poster Session I (No. 1-14) LECTURE HALL B 16:30– 18:15 19:30 12 MAC 4 Endoleaks and other follow-up issues after EVAR LECTURE HALL C 16:30– 18:15 MAC 5 Computational modeling of cardiovascular diseases and their treatment G E T- T O G E T H E R 13 PROGRAM AT A GLANCE Symposia and Workshops Friday, December 5th Miscellaneous LECTURE HALL B LECTURE HALL C Lunch Symposium I COOK 13:00– 13:50 Clinical practice in EVAR and experiences with Zenith Alpha™ Thoracic and Zenith t-Branch 13:00– 13:50 Lunch Symposium II LOMBARD The Aorfix™ Endovascular Stent Graft: a solution for the everyday to the extreme CONFERENCE ROOM I 14:00– 16:00 Workshop I TRIVASCULAR Saturday, December 6th OPERATION ROOM III 09:00– 10:00 Workshop II VASCUTEK HANDS-ON TRAINING Course I 10:30– 11:30 Workshop II VASCUTEK HANDS-ON TRAINING Course II CONFERENCE ROOM I 11:15– 12:15 Workshop III ENDOLOGIX OPERATION ROOM III 12:00– 13:00 Workshop II VASCUTEK HANDS-ON TRAINING Course III LECTURE HALL B 13:10– 14:00 14 Lunch Symposium III CORDIS First practical experiences with the 14 F ultra low profile INCRAFT AAA Stent Graft System LECTURE HALL C Lunch Symposium IV GE 13:10– 14:00 Hybrid-OR Workflow symposium: Interventional procedures using 3D image fusion and implications on dose PROGRAM PROGRAM Friday, December 5 Friday, December 5th LECTURE HALL B Carotid issues Aortic issues 09:00 Welcome R. Lange, Munich, Germany th LECTURE HALL C 09:00 LECTURE HALL B LECTURE HALL C The ascending aorta: Is the endovascular approach realistic? Welcome A. Zernecke, Würzburg, Germany T. Kölbel, Hamburg, Germany 09:00– MAC 1 10:40 Endovascular solutions for the ascending aorta and arch aneurysms Chair: M. Jacobs, Maastricht / Aachen, The Netherlands / Germany; R. Lange, Munich, Germany Incidence and treatment options for retrograde type A dissections after TEVAR 09:00– MCC 1 10:40 Advances in carotid plaque J. Pelisek, Munich, Germany Redo procedures for arch diseases – endo or open? biology Chair: J. Pelisek, Munich, Germany; A. Zernecke, Würzburg, Germany MicroRNAs in atherosclerosis The impact of patient age on carotid atherosclerosis – results from the Munich carotid biobank M. Jacobs, Maastricht / Aachen, The Netherlands / Germany 10:40– 11:05 COFFEE BREAK IN THE EXHIBITION AREA C. Weber, Munich, Germany M. Czerny, Zurich, Switzerland Ascending aortic TEVAR – the first FDA–approved study Role of vascular stem cells in atherosclerosis A. Khoynezhad, Los Angeles, USA Q. Xu, London, UK Planning of branched grafts and in-situ-fenestration for endovascular aortic arch repair miR-92a in atherosclerosis X. Loyer, Paris, France T. A. Resch, Malmö, Sweden Aortic arch repair with branched endografts Macrophage polarization and epigenetic regulation in atherosclerosis S. Haulon, Lille, France M. de Winther, Amsterdam, The Netherlands TEVAR and chimneys for arch pathologies – results from the PERICLES registry Abstract I: Neutrophil gelatinase-associated lipocalin (NGAL): clinical relevance in carotid atherosclerosis K. Donas, Münster, Germany W.-H. Eilenberg, Vienna, Austria Endografting and adjuncts for aortic arch aneurysms P. Kasprzak, Regensburg, Germany Long-term results after TEVAR and supraaortic debranching procedures Activation of the proapoptotic unfolded protein response in plaques of the human carotid artery B. Dorweiler, Mainz, Germany S. Ockert, Luzern, Switzerland; C. Reeps, Munich, Germany 16 17 PROGRAM PROGRAM Friday, December 5 Friday, December 5th LECTURE HALL B Carotid issues Aortic issues 11:05– MAC 2 12:35 Aortic emergencies I: acute Keynote lecture LECTURE HALL C Type B Aortic Dissection (TBAD) MCC 2 Carotid ultrasound beyond the degree of stenosis Chair: E. S. Debus, Hamburg, Germany; F. L. Moll, Utrecht, The Netherlands Chair: E. Bartels, Munich, Germany; H. Sillesen, Copenhagen, Denmark Emergency treatment of TBAD in patients with connective tissue disease Juxtaluminal black plaque area represents vulnerable carotid plaques R. Gibbs, London, UK S. Kakkos, Patras, Greece Treatment options for malperfusion in TBAD Contrast-enhanced ultrasound to assess neovascularization of the carotid bifurcation G.Torsello, Münster, Germany Indications and outcomes for hybrid procedures in acute TBAD Miscellaneous th E. S. Debus, Hamburg, Germany Symptoms, treatment options and outcomes of TBAD – a single center series 11:05– 12:30 D. Staub, Basel, Switzerland Contrast-enhanced ultrasound of the carotid bifurcation – our experiences at the Klinikum rechts der Isar K. Stock, Munich, Germany B. Reutersberg, Munich, Germany Prediction of growth of uncomplicated TBAD IMT measurement: useful or useless? What can we learn from actual studies? F. L. Moll, Utrecht, The Netherlands D. Sander, Tutzing, Germany Predictors of clinical success after TEVAR for TBAD Asymptomatic carotid stenosis in the High Risk Plaque (HRP) study I. Loftus, London, UK H. Sillesen, Copenhagen, Denmark TEVAR is beneficial in selected patients with uncomplicated TBAD – but the final answer can only be given by a RCT The role of cerebral vasoreactivity and emboli signal detection in the prediction of carotid-related strokes F. Mussa, New York, USA E. B. Ringelstein, Münster, Germany LECTURE HALL B 12:35– 12:55 Keynote lecture Thoracoabdominal aortic aneurysms H. J. Safi, Houston, USA Introduction: M. Jacobs, Maastricht / Aachen, The Netherlands / Germany 12:55– 14:00 LUNCH BREAK IN THE EXHIBITION AREA 13:00– 13:50 Lunch Symposium I COOK 13:00– 13:50 Lunch Symposium II LOMBARD Clinical practice in EVAR and experiences with Zenith Alpha™ Thoracic and Zenith t-Branch The Aorfix™ Endovascular Stent Graft: a solution for the everyday to the extreme Chair: P. Kasprzak, Regensburg, Germany Chair: J. Tessarek, Lingen, Germany Why is a durable repair important? Single-center case series: how Aorfix can address angulated necks and tortuous iliacs P. Kasprzak, Regensburg, Germany Experiences with Zenith Alpha™ Thoracic Endovascular Graft R. Kellersmann, Würzburg, Germany G. Torsello, Münster, Germany 7-year clinical experience with Aorfix Zenith t-Branch: an off-the-shelf solution for endovascular treatment of thoracoabdominal aneurysms J. Hardman, Bath / Bristol, UK B. Modarai, London, UK V. Makaloski, Berne, Switzerland Discussion Procedural overview and tips & tricks Pan-European experience with Aorfix N. Mosquera, Ourense, Spain DEBATE: TEVAR should be the standard of care for uncomplicated acute TBAD - for the motion J. Brunkwall, Cologne, Germany - against the motion A. Khoynezhad, Los Angeles, USA 18 15 19 PROGRAM PROGRAM Friday, December 5 Friday, December 5th LECTURE HALL B MAC 3 Aortic emergencies II: ruptured AAA 14:00– 15:15 LECTURE HALL B MCC 3 Functional imaging of atherosclerotic lesions 15:20– 16:00 Keynote lectures Sensing and imaging needs in modern vascular medicine Chair: P. Lawrence, Los Angeles, USA; M. Malina, Malmö, Sweden Chair: J. Rudd, Cambridge, UK; M. Schwaiger, Munich, Germany V. Ntziachristos, Munich, Germany Introduction: M. Schwaiger, Munich, Germany Abstract II: Forecasting AAA rupture – seasonal and atmospheric associations 3D Black-Blood Imaging of the vessel wall and beyond P. Lawrence, Los Angeles, USA A. Choong, London / Queensland, UK / Australia DEBATE: With appropriate adjuncts almost 100% of rAAAs can be treated by EVAR The role of PET imaging in the evaluation of carotid plaques F. Hyafil, Munich, Germany - pro F. J. Veith, New York, USA F. Mussa, New York, USA - con Improving care of patients with ruptured AAA: lessons from USA and UK R. Hinchliffe, London, UK Theory and practise of vascular surgical training in the 21st century 16:00– 16:30 T. Saam, Munich, Germany PET-MR for asymptomatic carotid stenosis: the final answer on who needs carotid intervention J. Schmidli, Berne, Switzerland Miscellaneous LECTURE HALL C The role of FDG-PET for the evaluation of novel therapies aimed at plaque stabilization J. Rudd, Cambridge, UK Introduction: H.-H. Eckstein, Munich, Germany COFFEE BREAK IN THE EXHIBITION AREA PAVILLON P A R A L L E L W O R K S H O P S page 29 Keynote lecture Carotid issues Aortic issues 14:00– 15:15 th 16:00– 17:30 Poster Session I (No. 1-14) Chair: A. Assadian, Vienna, Austria; T. Mastracci, Cleveland / London, USA / UK EndoAnchors in urgent AAA – does it work? J. P. de Vries, Nieuwegein, The Netherlands Neck length predicts outcome of ruptured AAA independently of repair F. Dick, Berne, Switzerland An update on the abdominal compartment syndrome. What is new? M. Björck, Uppsala, Sweden 20 21 PROGRAM PROGRAM Friday, December 5 Friday, December 5th LECTURE HALL B Aortic issues 16:30– 18:15 MAC 4 Endoleaks and other follow-up issues after EVAR Chair: T. Köppel, Munich, Germany; C. Liapis, Athens, Greece th LECTURE HALL C 16:30– 18:15 LECTURE HALL B Stratified surveillance and long-term mortality after EVAR MAC 5 Computational modeling of cardiovascular diseases and their treatment R. Hinchliffe, London, UK DEBATE: Despite all this, EVAR is safe and durable, the debate about EVAR versus OR should be finished Chair: M. Gee, Garching, Germany; D. Liepsch, Munich, Germany; W. Wall, Munich, Germany De novo periaortic inflammatory reaction after EVAR Prediction of EVAR outcome by means of computational models - for the motion A. Stella, Bologna, Italy F. Auricchio, Pavia, Italy - against the motion Iliac endograft thrombosis and reinterventions after EVAR Ultrasound based characterization of aortic and carotid vessel wall properties M. Jacobs, Maastricht / Aachen, The Netherlands / Germany A. Mansilha, Porto, Portugal F. van de Vosse, Eindhoven, The Netherlands Failure modes of infrarenal stentgrafts in AAA – Go FEVAR! New MR imaging methodology to measure the elasticity of the aortic wall in vivo M. Malina, Malmö, Sweden 19:30 T. Mastracci, Cleveland / London, USA / UK LECTURE HALL C G E T- T O G E T H E R R. Clough, London, UK Detection of type II endoleaks by CTA or MRA and what is a durable (>5 years) treatment? F. J. Moll, Utrecht, The Netherlands Abstract III: Dissection properties and mass fractions of the AAA wall and the intraluminal thrombus T. Cohnert, Graz, Austria Mid-term results of 107 reinterventions after complicated EVAR J. P. de Vries, Nieuwegein, The Netherlands Abstract IV: Determining the biomechanical properties of infrarenal aortic aneurysms W. Derwich, Frankfurt, Germany Coil and glue embolisation of type II endoleaks - a critical review I. Loftus, London, UK Coping with parametric uncertainty in the computational assessment of AAA rupture risk J. Biehler, Garching, Germany 22 Influence of normal post procedural CT on requirement for secondary intervention after EVAR in an unselected population The change of geometrical and biomechanical properties during AAA expansion J. Scott, Leeds, UK T. C. Gasser, Stockholm, Sweden 23 PROGRAM LECTURE HALL C MAC 6 Aortic emergencies III: the infected aorta LECTURE HALL B 09:00– 10:30 MCC 4 The future of Carotid Artery Stenting (CAS) 11:00– 12:35 MAC 7 Perioperative imaging, fusion and navigation MCC 5 Asymptomatic carotid disease Chair: S. Haulon, Lille, France; A. Zimmermann, Munich, Germany Chair: B. Hemmer, Munich, Germany; R. Naylor, Leicester, UK New less invasive paradigm for treating aortic infection Which patient subgroups do benefit from CAS? M. Malina, Malmö, Sweden A. Stella, Bologna, Italy Patient and surgeon radiation protection during endovascular procedures Aortic graft infection – current diagnosis and management, including in-line autogenous reconstruction What kind of training and volume is necessary to perform CAS safely? Abstract VII: The prevalence of carotid stenosis and atrial fibrillation amongst 4 million screened US adults and the importance of smoking as a risk factor A. Dörfler, Erlangen, Germany Will the newest generation carotid stents resuscitate CAS? M. Bosiers, Dendermonde, Belgium M. Björck, Uppsala, Sweden Self-made pericardial tube grafts for infected aortic protheses C. Reeps, Munich, Germany Our experience in acute CAS with our strategy of selection and procedure G. Coppi, Modena, Italy Are there still indications for silver and antibiotic-coated grafts? A. Assadian, Vienna, Austria Abstract V: Deep veins for aortic reconstruction Despite current level 1 evidence, the outlook for an upsurge in CAS is bright F. J. Veith, New York, USA C. Domenig, Vienna, Austria Abstract VI: Two-step hybrid technique for the treatment of secondary aortoenteric fistula using endovascular aortic occlusion followed by surgical explant and intestinal repair G. Coppi, Modena, Italy C. Liapis, Athens, Greece Fusion technology for intraoperative dose reduction S. Haulon, Lille, France Sealing of endografts and the fate of the supra- and infrarenal angulation after EVAR – new software solution J. P. de Vries, Nieuwegein, The Netherlands Vessel Navigator: a new fusion technique to reduce contrast media and radiation J. Brunkwall, Cologne, Germany Fusion techniques to facilitate navigation in fenestrated and branched endografting G. Panuccio, Münster, Germany Abstract IX: VIII: Abstract An experimental setAnfor experimental set-up for navigaup navigated-contrast-agent ted-radiation contrast-agent and radiation and sparing endovascular sparing endovascular aortic repair aortic repair M.Kleemann, Kleemann,Lübeck, Lübeck,Germany Germany M. Preoperative imaging of spinal perfusion in thoracoabdominal aneurysms A. Huber, Munich, Germany 24 11:00– 12:35 Chair: L. Bonati, Basel, Switzerland; F. J. Veith, New York, USA EVAR for mycotic aortic aneurysms, a multinational experience of 132 cases 10:30– 11:00 LECTURE HALL B Chair: M. Björck, Uppsala, Sweden; M. Steinbauer, Regensburg, Germany P. Lawrence, Los Angeles, USA Miscellaneous LECTURE HALL C P A R A L L E L W O R K S H O P S page 29 Carotid issues Aortic issues 09:00– 10:30 Saturday, December 6th COFFEE BREAK IN THE EXHIBITION AREA R. Bulbulia, Oxford, UK Predictors and clinical significance of progression or regression of asymptomatic carotid stenosis S. Kakkos, Patras, Greece Plaque structure is relevant for risk stratification in asymptomatic carotid disease. Its clinical use is mandatory J. Fernandes e Fernandes, Lisbon, Portugal Biomarkers – might they help to identify carotid patients at risk? C. Liapis, Athens, Greece P A R A L L E L W O R K S H O P S page 29 Saturday, December 6 PROGRAM th DEBATE: Do we really need a new definition of “stroke and TIA” (as proposed by the AHA)? Yes, because modern neuroimaging can clearly identify cerebral infarction P. Ringleb, Heidelberg, Germany No, stroke and TIA need to remain clinical diagnoses: to change would be bonkers! A. Abbott, Melbourne, Australia 25 PROGRAM Saturday, December 6 PROGRAM Saturday, December 6th th LECTURE HALL B Keynote lecture Aortic issues Why the ongoing initiative to separate physicians from industry is bad for patient care and society F. J. Veith, New York, USA Introduction: H.-H. Eckstein, Munich, Germany Carotid issues PAVILLON 13:00– Poster Session II (No. 15-27) 14:00 Keynote lecture 14:00– 15:45 MCC 6 Carotid trials and the impact of TIME in symptomatic patients Chair: H.-H. Eckstein, Munich, Germany; H. Poppert, Munich, Germany Current guidelines on carotid disease are obsolete and have to be improved! A. Abbott, Melbourne, Australia Status and perspectives of ECST-2 and CREST-2 L. Bonati, Basel, Switzerland Chair: J. Schmidli, Berne, Switzerland; J. Scott, Leeds, UK Update of ACST 2 13:00– 14:00 13:10– 14:00 A. Halliday, Oxford, UK LUNCH BREAK IN THE EXHIBITION AREA LECTURE HALL B Miscellaneous PA R A L L E L W O R K S H O P S page 29 12:40– 13:00 LECTURE HALL B Lunch Symposium III CORDIS First practical experiences with the 14F ultra low profile INCRAFT AAA Stent Graft System SPACE-2, why was the protocol modification not successful? LECTURE HALL C 13:10– 14:00 P. Ringleb, Heidelberg, Germany Lunch Symposium IV GE Chair: M. Sadeghi, Erding, Germany (tbc) Hybrid-OR Workflow symposium: Interventional procedures using 3D image fusion and implications on dose First practical experiences from the St. Franziskus Hospital, Münster Fusion imaging technique: why, how, where? B. Gehringhoff, Münster, Germany S. Haulon, Lille, France First practical experiences from the Klinikum rechts der Isar How fusion imaging has found its place during abdominal CTO? C. Reeps, Munich, Germany K. Overbeck, Sunderland, UK Time heals all wounds….? Natural history and the risk of early interventions in symptomatic carotid disease R. Naylor, Leicester, UK Long-term outcome after CAS versus CEA for symptomatic carotid stenosis: new data from ICSS and the Carotid Stenosis Trialists’ Collaboration L. Bonati, Basel, Switzerland Is a short time interval between the neurological index event a risk factor for CEA or CAS? – a nationwide analysis of CEA and CAS for symptomatic patients in Germany P. Tsantilas, Munich, Germany; A. Kühnl, Munich, Germany 15:45 FAREWELL H.-H. Eckstein, Munich, Germany Benefits of advanced imaging techniques during peripheral procedures M. Bosiers, Dendermonde, Belgium 26 27 WORKSHOPS CONFERENCE ROOM I 14:00– 16:00 (Friday, December 5th) Workshop I TRIVASCULAR Ovation Prime – the science of seal Causes and risks of aortic neck dilatation: the evolution of a novel technology to preserve the aortic neck R. Whirley, Santa Rosa, USA TRAINING: Ovation Prime Hands-On, Indication and Case-planning OPERATION ROOM III (Saturday, December 6th) Workshop II VASCUTEK Fenestrated anacondaTM 09:00– 10:00 HANDS-ON TRAINING Course I 10:30– 11:30 HANDS-ON TRAINING Course II 12:00– 13:00 HANDS-ON TRAINING Course III CONFERENCE ROOM I 11:15– 12:15 (Saturday, December 6th) Workshop III ENDOLOGIX Chair: A. Oberhuber, Düsseldorf, Germany Nellix, what else? Single-center experience with 40 Nellix implantations A. Oberhuber, Düsseldorf, Germany HANDS-ON TRAINING www.mac-conference.com 29 Carotid issues Aortic issues POSTERSESSIONS AND 1. Protective role of statin therapy in thoracoabdominal aortic surgery J. Grommes; A. Greiner, Aachen, Germany 23. The ration of Apolipoptotein A-II/B predicts overall survival after carotid surgery N. Duschek, Vienna, Austria 2. A comparison between contrast-enhanced ultrasound and CTA in detecting and classifying endoleaks after EVAR G. Meimarakis, Munich, Germany 24. Low homocysteine concentrations predict a higher likelihood of TIA than stroke in patients with a symptomatic carotid stenosis N. Duschek, Vienna, Austria 3. The influence of the Ovation’s Stent Graft fixation mode on the direct postoperative suprerenal neck angulation change; comparison to the Nitinol self-expanding stent mechanism E. Georgakarakos, Alexandroupolis, Greece 4. Establishment of a 3D-Model of the murine aortic arch A. Glinzer, Munich, Germany 5. Combined surgery on the aorta, carotid artery and thyroid gland P. Stepinski, Nowa Sol, Poland 6. Emergent open interventions after EVAR: strategies and outcome C. Domenig, Vienna, Austria 7. TEVAR for blunt aortic injury V. Makaloski, Berne, Switzerland 8. TEVAR implantation as elephant trunk during conventional arch replacement N. Tabuchi, Yokohama, Japan Long-term patency of renal and visceral vessels after open TAAA repair B. Dorweiler, Mainz, Germany First results of ChEVAS (Chimney EndoVascular Aneurysm Sealing) S. Zerwes, Augsburg, Germany 11. Renal ischemic lesion in fEVAR R. Pini, Modena, Italy 12. Fenestrated/branched endograft after previous aortic surgery E. Gallitto, Bologna, Italy Initial single-center experience with the Ovation stent-graft system E. Georgakarakos, Alexandroupolis, Greece 9. 10. 13. 25. Aneurysm of the brachiocephalic trunk and a tracheal fistula – case report D. Metz, Halle a. d. Saale, Germany 26. The utility of Piton catheter in TEVAR A. Lauricella, Modena, Italy 27. Perioperative visual field changes after carotid endarterectomy P. Konstantiniuk, Graz, Austria The best two posters will be awarded with EUR 500.00 each! Oral Presentations | Friday, December 5th Abstract I Neutrophil gelatinase-associated lipocalin (NGAL): clinical relevance in carotid atherosclerosis in MCC 1 09:00–10:40 W.-H. Eilenberg, Vienna, Austria Abstract II Forecasting AAA rupture – seasonal and atmospheric associations in MAC 3 14:00–15:15 A. Choong, London / Queensland, UK / Australia Abstract III Dissection properties and mass fractions of the AAA wall and the intraluminal thrombus in MAC 5 16:30–18:15 T. Cohnert, Graz, Austria Abstract IV Determining the biomechanical properties of infrarenal aortic aneurysms in MAC 5 16:30–18:15 W. Derwich, Frankfurt, Germany 14. Identification of material parameters of soft tissue: toward inverse A S. Kehl, Garching, Germany 15. Blunt traumatic thoracic aortic injury: time for a standardised grading system? A. Choong, London / Queensland, UK / Australia Endovascular aneurysm repair via carotid artery access: a viable alternative? A. Choong, London / Queensland, UK / Australia Abstract V Deep veins for aortic reconstruction 16. in MAC 6 09:00–10:30 C. Domenig, Vienna, Austria First experience of endovascular sealing (Nellix) in a ruptured abdominal aortic aneurysm: a case report of an elderly patient Abstract VI 17. G. Saitta, Modena, Italy in MAC 6 09:00–10:30 Two-step hybrid technique for the treatment of secondary aortoenteric fistula using endovascular aortic occlusion followed by surgical explant and intestinal repair 18. Paraplegia prevention in TEVAR: the use of Remifentanyl S. Gennai, Modena, Italy 19. NELLIX 2.0: single-center experience with 40 NELLIX implantations H. Schelzig, Düsseldorf, Germany First experiences with self-made pericardial tube grafts for infected 20. aortic grafts 30 ORAL PRESENTATIONS Oral Presentations | Saturday, December 6th G. Coppi, Modena, Italy B. Lutz, Munich Germany Abstracts VII in MCC 5 11:00–12:35 R. Bulbulia, Oxford, UK Abstract VIII in MAC 7 11:00–12:35 21. The impact of time on outcome of CEA in symptomatic patients P. Tsantilas, Munich, Germany 22. Carotid surgery risk stratification J. Basic, Vienna, Austria The prevalence of carotid stenosis and atrial fibrillation amongst 4 million screened US adults and the importance of smoking as a risk factor An experimental set-up for navigated- contrast-agent and radiation sparing endovascular aortic repair M. Kleemann, Lübeck, Germany The best oral Presentation will be awarded with EUR 500.00! 31 KEYNOTE LECTURES n Thoracoabdominal aortic aneurysms th Prof. Hazim J. Safi, MD Houston | USA Munich | Germany 32 n Theory and practise of vascular surgical training in the 21st century December 5 , 2014 | 12:35–12:55 December 5th, 2014 | 15:40–16:00 Hazim J. Safi is one of the leading specialists worldwide for open thoracoabdominal aortic surgery. He is Professor and Chairman of the Department of Cardiothoracic and Vascular Surgery at the University of Texas Medical School in Houston and also author and co-author of more than 30 book chapters and over 200 scientific publications in medical journals. His profound clinical experience in treatment and management of complex aortic disease and his scientific work have helped to develop surgical techniques which greatly improve outcomes of complex aortic surgery. Dr. Lawrence graduated from Dartmouth College and was awarded his M.D. degree with honors from Harvard Medical School. His surgical residency and vascular fellowship were done at Columbia-Presbyterian Medical Center in New York City. In 1978, he joined the faculty at the University of Utah, where he served as chief of Surgery at the Veterans Administration Hospital, chair of the Division of Vascular Surgery and president of the medical staff. He moved to UC Irvine in 1998 to become the associate dean for clinical affairs, vice president for specialty services, and professor of surgery. In 2003, he moved to UCLA to become the chief of vascular surgery and the director of the Gonda (Goldschmied) Vascular Center, as well as the Bergman chair in vascular research. n Sensing and imaging needs in modern vascular medicine n Why the ongoing initiative to separate physicians from industry December 5th, 2014 | 15:20–15:40 Vasilis Ntziachristos KEYNOTE LECTURES Professor Ntziachristos’ area of research encompasses the development of new methods and devices for biological and medical imaging. The aim is to achieve sustained improvements in the non-invasive investigation of physiological and molecular processes in tissues. The result will be the development of novel, minimally invasive and highly efficient methods for diagnosing and treating lifethreatening diseases such as cancer and arteriosclerosis. Professor Ntziachristos (b. 1970) initially studied electrical engineering at Aristotle University in Thessaloniki, Greece. After graduation, he transferred to the Faculty of Bioengineering at the University of Pennsylvania, where he obtained his MSc. and PhD. He was assistant Professor and Director of the Laboratory for Bio-Optics and Molecular Imaging at Harvard University and Massachusetts General Hospital, before being appointed to the Chair of Biological Imaging at TUM in 2007. The Chair is closely linked with the Institute for Biological and Medical Imaging at the Helmholtz Centre in Munich, of which Professor Ntziachristos is Director. Peter Lawrence Los Angeles | USA is bad for patient care and society December 6th, 2014 | 12:40–13:00 Frank J. Veith graduated from Cornell University Medical School before completing an internship at Columbia-Presbyterian Hospital in New York and residency training at Peter Bent Brigham Hospital and Harvard Medical School. In the 1970s and 80s he turned his attention toward vascular surgery with an emphasis on lower extremity revascularization procedures and the endovascular graft repair of abdominal aortic aneurysms. Frank Veith’s group was the first to perform an endovascular aneurysm repair in the United States. Frank Veith held positions as Chief of Vascular Surgery and Chairman of Surgery at Montefiore Medical Center and Albert Einstein College of Medicine for many years. Moreover, he has held the William J. von Liebig Chair in Vascular Surgery and has been the Vice Chairman of the Department of Surgery. In 1995 he was elected President of the Society for Vascular Surgery, and is past Chairman of the American Board of Vascular Surgery. He is chief-editor of VASCULAR and is organizing the VEITH Symposium in New York for 40 years. Frank J. Veith New York | USA 33 FACULTY CHAIRMAN Technische Universität München, TUM | Munich | Germany n Hans-Henning Eckstein CO-CHAIRMEN Technische Universität München, TUM | Munich | Germany n Rüdiger Lange n Markus Schwaiger n Holger Poppert n Wolfang Wall n Michael Gee n Alma Zernecke, Würzburg, Germany LOCAL COORDINATING COMMITTEE Technische Universität München, TUM | Munich | Germany n Kathrin Berkenkamp n Ulf Herold n Eva Knipfer n Jaroslav Pelisek n Christian Reeps n Heidi Söllner n Bernhard Voss n Heiko Wendorff n Alexander Zimmermann 35 FACULTY SCIENTIFIC FACULTY n Anne Abbott, Melbourne, Australia n Afshin Assadian, Vienna, Austria n Ferdinando Auricchio, Pavia, Italy n Eva Bartels, Munich, Germany n Jonas Biehler, Garching, Germany n Martin Björck, Uppsala, Sweden n Leo Bonati, Basel, Switzerland n Marc Bosiers, Dendermonde, Belgium n Jan Brunkwall, Cologne, Germany n Alison Halliday, Oxford, United Kingdom n John Hardman, Bath / Bristol, United Kingdom n Haulon, Lille, France n Stephan Hans-Henning Eckstein n Bernhard Hemmer, Munich, Germany n Rob Hinchliffe, London, United Kingdom n Armin Huber, Munich, Germany n Fabien RüdigerHyafil, LangeMunich, Germany n Jacobs, Maastricht / Aachen, The Netherlands / Germany n Michael Markus Schwaiger n n n n Stavros Kakkos, Patras, Greece Holger Poppert Piotr Alma Kasprzak, Zernecke Regensburg, Germany n Rachel Clough, London, United Kingdom n n n n n n Gioachino Coppi, Modena, Italy n Thomas Köppel, Munich, Germany n Richard Bulbulia, Oxford, United Kingdom n Andrew Choong, London / Queensland, United Kingdom / Australia n Tina Cohnert, Graz, Austria n Martin Czerny, Zurich, Switzerland n Jean Paul de Vries, Nieuwegein, The Netherlands n Menno de Winther, Amsterdam, The Netherlands n E. Sebastian Debus, Hamburg, Germany n Wojciech Derwich, Frankfurt, Germany n Florian Dick, Berne, Switzerland n Christoph Domenig, Vienna, Austria n Konstantinos Donas, Münster, Germany n Arnd Dörfler, Erlangen, Germany Richard Kellersmann, Würzburg, Germany Wolfang Wall Ali Khoynezhad, Los Angeles, USA Michael Gee Markus Kleemann, Lübeck, Germany n Tilo Kölbel, Hamburg, Germany n n n n n n n n n n n n n n n Andreas Kühnl, Munich, Germany Ulf Herold Peter Lawrence, Los Angeles, USA Eva Knipfer Christos Liapis, Athens, Greece Jaroslav Pelisek Dieter Liepsch, Munich, Germany Christian Reeps Ian Loftus, London, United Kingdom Heidi Söllner Xavier Loyer, Paris, France Bernhard Voss Vladimir Makaloski, Berne, Switzerland Alexander Zimmermann Martin Malina, Malmö, Sweden n Armando Mansilha, Porto, Portugal n T. Christian Gasser, Stockholm, Sweden n n n n n n n n Richard Gibbs, London, United Kingdom n Ross Naylor, Leicester, United Kingdom n Bernhard Dorweiler, Mainz, Germany n Wolf-Hans Eilenberg, Vienna, Austria n José Fernandes e Fernandes, Lisbon, Portugal n Bernd Gehringhoff, Münster, Germany 36 FACULTY Tara Mastracci, Cleveland / London, USA / United Kingdom Afshin Assadian Bijan Modarai, London, United Kingdom Heinrich Audebert Frans L. Moll, Utrecht, The Netherlands Martin Austermann Nilo Mosquera, Ourense, Spain n Firas Mussa, New York, USA 37 FACULTY SPONSORS n Vasilis Ntziachristos, Munich, Germany GOLD n Alexander Oberhuber, Düsseldorf, Germany n Stefan Ockert, Luzern, Switzerland n Klaus Overbeck, Sunderland, United Kingdom n Giuseppe Panuccio, Münster, Germany n Timothy A. Resch, Malmö, Sweden n Benedikt Reutersberg, Munich, Germany n E. Bernd Ringelstein, Münster, Germany n Peter Ringleb, Heidelberg, Germany n James Rudd, Cambridge, United Kingdom SILVER n Tobias Saam, Munich, Germany n Hazim J. Safi, Houston, USA n Mojtaba Sadeghi, Erding, Germany n Dirk Sander, Tutzing, Germany n Jürg Schmidli, Berne, Switzerland n Julian Scott, Leeds, United Kingdom BRONZE n Henrik Sillesen, Copenhagen, Denmark n Daniel Staub, Basel, Switzerland n Markus Steinbauer, Regensburg, Germany n Andrea Stella, Bologna, Italy n Konrad Stock, Munich, Germany n Jörg Tessarek, Lingen, Germany n Giovanni Torsello, Münster, Germany n Pavlos Tsantilas, Munich, Germany n Frans van de Vosse, Eindhoven, The Netherlands n Frank J. Veith, New York, USA n Christian Weber, Munich, Germany n Robert Whirley, Santa Rosa, USA n Qingbo Xu, London, United Kingdom 38 EXHIBITORS PASSIV n n n n n n n Medistim Deutschland GmbH n n n n n APTUS Endosystems, Inc. Boston Scientific Medizintechnik GmbH C.R. Bard GmbH Covidien Deutschland GmbH GE Healthcare GmbH Johnson & Johnson Medical GmbH (Cordis, Ethicon, Ethicon Surgery) Jotec GmbH LeMaitre Vascular GmbH MAQUET Vertrieb & Service Deutschland GmbH Nicolai GmbH Pharmore GmbH Listing as per November 7th, 2014 39 DIRECTIONS We highly recommend to use public transportation as the Klinikum rechts der Isar offers very limited parking possibilities. n FROM MUNICH AIRPORT Please follow the signs “S-Bahn“ at the main terminal of the airport to the train station. We recommend using the line S8 towards Munich (München) to the station “Ostbahnhof”. Then change to the underground line U5 or U4 (U-Bahn) in direction to “Max-Weber-Platz” and get off at the station “Max-Weber-Platz”. Follow the signs “Einsteinstrasse” and “Einsteinstrasse/Klinikum rechts der Isar”. n FROM CENTRAL TRAIN STATION (HAUPTBAHNHOF) Follow the signs to the underground station and take line U4 /Arabellapark or U5/ Neuperlach. Get off the train at “Max-Weber-Platz” which is only four stations from the central train station. Follow the signs “Einsteinstrasse” and “Einsteinstrasse/ Klinikum rechts der Isar”.
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