THE JOURNAL OF EXPERIMENTAL MEDICINE Executive Editor Marlowe S.Tessmer phone (212) 327-8575 fax (212) 327-8511 email: [email protected] Senior Editor Heather L. Van Epps Scientific Editors Teodoro Pulvirenti Catarina Sacristán Editors Jean-Laurent Casanova David Holtzman Lewis L. Lanier William A. Muller Carl Nathan Michel Nussenzweig Anne O’Garra Alexander Rudensky Alan Sher Sasha Tarakhovsky Andreas Trumpp David Tuveson Editor Emeritus Alan N. Houghton Manuscript Coordinator Sylvia F. Cuadrado phone (212) 327-8575 fax (212) 327-8511 email: [email protected] Preflight Editor Rochelle Ritacco Assistant Production Editors Brianna Caszatt and Shauna O’Garro Production Editor Maya Frank-Levine Production Manager Camille Clowery Advisory Editors Shizuo Akira Kari Alitalo Frederick W. Alt K. Frank Austen Albert Bendelac Michael J. Bevan Christine A. Biron Christian Bogdan Hal E. Broxmeyer Meinrad Busslinger Arturo Casadevall Ajay Chawla Yongwon Choi Robert L. Coffman Daniel J. Cua Myron I. Cybulsky Riccardo Dalla Favera Glenn Dranoff Michael Dustin Douglas T. Fearon Vincent A. Fischetti Richard A. Flavell Adolfo Garcia-Sastre Patricia Gearhart Ronald N. Germain Christopher Goodnow Siamon Gordon Or Gozani Sergio Grinstein Philippe Gros Kristian Helin Chyi Hsieh Christopher A. Hunter Kayo Inaba Gerard Karsenty Jay Kolls Paul Kubes Vijay K. Kuchroo Ralf Kuppers Tomohiro Kurosaki Bart N. Lambrecht Klaus F. Ley Yong-Jun Liu Clare Lloyd Tak Mak Bernard Malissen James S. Malter Philippa Marrack Diane Mathis Ira Mellman Matthias Merkenschlager Sean J. Morrison Muriel Moser Christian Münz Cornelis Murre Benjamin G. Neel Michael Neuberger Victor Nussenzweig John J. O’Shea Paul H. Patterson Fiona Powrie Lluis Quintana-Murci Klaus Rajewsky Gwendalyn J. Randolph Jeffrey Ravetch Sergio Romagnani Nikolaus Romani David L. Sacks Shimon Sakaguchi Matthew D. Scharff Olaf Schneewind Stephen P. Schoenberger Hans Schreiber Gerold Schuler Robert A. Seder Rafick-P. Sékaly Charles N. Serhan Nilabh Shastri Ethan M. Shevach Roy L. Silverstein Jonathan Sprent Janet Stavnezer Andreas Strasser Stuart Tangye Steven L.Teitelbaum Thomas J.Templeton Kevin J.Tracey Giorgio Trinchieri Shannon Turley Marcel R.M. van den Brink Ulrich von Andrian Harald von Boehmer Christopher M.Walker Raymond M.Welsh E. John Wherry Linda S.Wicker Ian Wilson Thomas Wynn Monitoring Editors Marco Colonna Jason Cyster Stephen Hedrick Kristin A. Hogquist Andrew McMichael Luigi Notarangelo Anjana Rao Federica Sallusto Louis M. Staudt Toshio Suda Consulting Biostatistics Editors Glenn Heller Madhu Mazumdar Production Designer Erinn A. Grady Copyright to articles published in this journal is held by the authors. Articles are published by The Rockefeller University Press under license from the authors. Conditions for reuse of the articles by third parties are listed at http://www.rupress.org/terms Print ISSN 0022-1007 Online ISSN 1540-9538 FINANCE DIRECTOR Raymond T. Fastiggi BUSINESS DEVELOPMENT DIRECTOR Gregory Flynn Malar DIRECTOR OF PUBLISHING TECHNOLOGIES Robert J. O'Donnell ADVERTISING SALES DIRECTOR Lorna Petersen COMMUNICATIONS MANAGER Rita Sullivan King OFFICE ADMINISTRATOR JoAnn Greene ASSISTANTS TO THE FINANCE DIRECTOR Sarah S. Kraft Ann Travers BUSINESS DEVELOPMENT SPECIALIST Colleen M. Smith MARKETING ASSOCIATE Laraine Karl The Journal of Experimental Medicine (ISSN 0022-1007) is published every four weeks (1 volume, 13 issues) by The Rockefeller University Press, 1114 First Avenue, New York, NY 10065-8325. Periodical postage paid at New York, NY and additional mailing offices. 2015 Subscription Rates: Institutional Rates: Tier 1 Online $1,500 Print+Online $3,400 Tier 2 $1,930 $3,760 Tier 3 $2,460 $4,020 Tier 4 $3,145 $5,145 Personal Rates: Print Only: $310 For more information, please contact the Circulation Department: Phone: 212-327-8572 Fax: 212-327-7944 email: [email protected] Advertising requests: Phone: 212-327-8880 Fax: 212-327-7944 email: [email protected] Permission requests: email: [email protected] Media requests: email: [email protected] Postmaster: Send address changes to The Journal of Experimental Medicine, Circulation Department, The Rockefeller University Press, 1114 First Avenue, New York, NY 10065-8325.
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