Conggratulations to o our faculty and a staff who o collaborated d on 117 posteers and presennted 16 paperrs/minisympoosiums at ARV VO 2015, conffirming that Bascom B Palm mer is the leadeer in vision reesearch. 2015 AR RVO Highllights Sun nday Posteers 185— —C0040 Trea atment of Co oats’ disease with intravittreal bevacizzumab and retinal laser p photocoagulaation. Julia Sein,, J. Tzu, A. M. M Berrocal. Bascom B Palmeer Eye Institutte, Miami, FL L 247— —C0119 AMutant Human T8993G ATP6 Transgeenic Mouse M Model With V Visual Loss, Paralysis an nd Death. Huijuun Yuan, H. Yu, Y J. Guy. Bascom B Palmeer Eye Institutte, Miami, FL L 271— —C0156 Mollecular and Mupirocin M Prrofiles of MS SSA and MR RSA Isolates A Associated w with Chronic//Recalcitrantt Ocullar Disease. Darlene D Milleer, J. Maestre,, E. Perez, B. D. Wilson, H H. W. Flynn, E E. C. Alfonsoo. Bascom Paalmer Eye Instittute, Univ of Miami Millerr Sch of Med,, Miami, FL 277— —C0162 Microbiological Isolates in Persistently P Culture C Posittive Endophtthalmitis. Ellaa H. Leung1, A. E. Kuriyyan1, H. W. Flynn1, F L. C. Huang2, D. Miller1. M 1Dep partment of O Ophthalmologgy, Bascom Palmer Eye Institute/ Univversity of Miaami, Miami, FL; F 2Universitty of Miami, Miami, FL 278— —C0163 Coa agulase-Nega ative Staphylo ococcus (CoN NS) Causing Endophthallmitis: A Deccreasing Tren nd of Suscceptibility Am mong Vancom mycin and Flluoroquinolo ones. Jack D. Stringham, D D. Miller, H. W W. Flynn. Opphthalmology y, Bascom Palmer Eye E Institute, Sunny S Isles, FL F —C0237 Hum man Tear Serrotonin Leveels and Neuro opathic Ocullar Pain in D Dry Eye. Priyyanka Chhadvva1, T. Lee1, 352— A. H Hackam1, A. L. L McClellan2 2, E. Felix2, 3, 3 C. Sarantop poulos2, 4, R.. Levitt2, 4, A A. Galor1, 2. 1Ophthalmollogy- Bascom m Palm mer Eye Institu u, University of Miami Miiller School off Medicine, M Miami, FL; 2M Miami Veteraans Administrration Mediical Center, Miami, M FL; 3P Physical Medicine and Reh habilitation, U University of Miami Millerr School of M Medicine, Miam mi, FL;4Anessthesiology, Perioperative P Medicine M and d Pain Managgement, Univeersity of Miam mi Miller Schhool of Mediicine, Miami,, FL 357— —C0242 Corneal Mechan nical Hyperseensitivity is Correlated C w with Wind Hyyperalgesia, Ocular Symptoms, and Systeemic Compla aints. Allison n L. McClellan n1, O. Spierer2, K. Ehrmaann3, J. A. Paarel2, 3, A. Goonzalez2, E. F Felix1 4, W. J. Feuuer2, C. Sarantopoulos1, 5, 5 R. Levitt1, 5, A. Galor1,, 2. 1Miami V Veterans Adm ministration M Medical Center, Miami, FL; 2Basscom Palmer Eye E Institute,, University of o Miami, Miaami, FL; 3Briien Holden V Vision Institutee, University of New Southh Wales, Syd dney, NSW, Australia; A 4Ph hysical Mediciine and Rehab abilitation, Unniversity of M Miami Miller S School of Mediicine, Miami,, FL; 5Anesth hesiology, Un niversity of Miami M Miller S School of Meddicine, Miam mi, FL 387— —D0123 The Novel Use of o Fluorescein n Angiography to Evaluaate Retinal H Hemorrhagess in Abusive H Head Trau uma. Audrey C. Ko, D. Ch hoi, N. W. Bleessing, S. R. Dubovy, D A. M M. Berrocal. O Ophthalmologgy, Universityy of Miam mi/Bascom Paalmer Eye Insstitute, Miamii, FL 465—A0189 PERG intrinsic variability across dynamic range. Pedro Monsalve1, J. Toft-Nielsen2, G. Triolo1, 3, R. Delgado2, E. Miskiel2, O. Ozdamar4, J. Bohorquez4, W. J. Feuer1, J. McSoley1, V. Porciatti1. 1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Intelligent Hearing Systems Corp., Miami, FL; 3Ophthalmology, University Scientific Institute San Raffaele, Milan, Italy; 4Biomedical Engineering, University of Miami, Miami, FL 470—A0194 Integrative properties of retinal ganglion cell function in mice studied with PERG. Tsung-Han Chou, V. Porciatti. Bascom Palmer Eye Inst, Univ of Miami, Miller Sch of Med, Miami, FL 479—A0203 Intravitreal CNTF transiently improves residual cone function inCNGB3−/− mouse. Dario Marangoni2, C. Vijayasarathy2, R. A. Bush2, L. Wei1, R. Wen3, P. A. Sieving1, 2. 1NEI, National Institutes of Health, Bethesda, MD;2NIDCD, National Institutes of Health, Bethesda, MD; 3Bascon Palmer Eye Institute, University of Miami, Miami, FL 490—A0214 Lower eyelid topography of PERG responses obtained at different pattern reversal rates. Jorge Bohorquez1, J. Toft-Nielsen2, N. Yesilirmak3, V. Porciatti3, O. Ozdamar1. 1Biomedical Engineering, University of Miami, Doral, FL; 2Intelligent Hearing Systems Corp, Miami, FL; 3Bascon Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 611—B0069 Uncertainty in the diagnosis of Pre-plus Disease in Retinopathy of Prematurity. Allison R. Loh1, M. Ryan1, K. Abrahams1, E. Ataer-Cansizoglu4, R. V. Chan2, A. M. Berrocal3, J. Kalpathy-Cramer5, V. Bolon-Canedo6, D. Erdogmus4, M. F. Chiang1. 1Ophthalmology, Oregon Health and Science University, Portland, OR; 2Ophthalmology, Weill Cornell Medical College, New York, NY; 3Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 4Electrical and Computer Engineering, Northeastern University, Boston, MA; 5Radiology, Harvard Medical School, Charleston, MA; 6Informatics, University of A Coruña, A Coruña, Spain 627—B0140 Area and volume analysis of the superior and inferior retinal nerve fiber layer (rNFL) bundles from SD-OCT thickness maps: correlation with visual field mean deviation (VFMD) and optic nerve head measurements. Andrew Camp3, W. J. Feuer3, J. Mwanza1, D. L. Budenz1, G. Triolo3, 2, P. Monsalve3, R. K. Parrish3, S. Gedde3, L. E. Vazquez3. 1University of North Carolina, Chapel Hill, NC; 2University Scientific Institute San Raffaele, Milan, Italy; 3Bascom Palmer Eye Institute, Miami, FL 693—C0141 Evaluation of Pre-existing Neutralizing Antibodies Against TyrosineMutant AAV2 in Leber Hereditary Optic Neuropathy (LHON) Patients. Rajeshwari D. Koilkonda1, W. W. Hauswirth2, V. Chiodo2, S. L. Boye2, P. Gonzalez1, J. Guy1. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Ophthalmology, University of Florida, Gainesville, FL 744—C0292 Clinicopathologic correlation of Corneal Keloid-like Myoblastic Fibrocellular Proliferation. Maria Paula Fernandez, A. Bermudez, S. R. Dubovy, E. C. Alfonso, V. L. Perez, G. Amescua, R. Forster. Ocular Pathology, Bascom Palmer Eye Institute, Miami, FL 795—D0257 Genotype at four loci associated with risk of advanced AMD does not predict progression rate from intermediate to advanced disease. Patrice Persad1, R. Sardell1, S. G. Schwartz2, J. L. Kovach2, J. Fortun2, M. A. Brantley3, A. Agarwal3, J. L. Haines4, W. Scott1, M. A. Pericak-Vance1. 1Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL; 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 3Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, TN; 4Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 797—D0259 Known Age-Related Macular Degeneration Risk Variants Are Not Associated with Rapid Disease Progression or Good Treatment Response. Monique D. Courtenay1, W. Cade1, G. Wang1, S. G. Schwartz2, J. L. Kovach2, A. Agarwal3, M. A. Brantley3, W. K. Scott1, J. L. Haines4, M. A. Pericak-Vance1. 1Hussman Institute for Human Genomics, University of Miami, Miami, FL; 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL;3Ophthalmology and Visual Sciences, Vanderbilt University, Nashville, TN; 4Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 800—D0262 Significant age-related accumulation and shortening of dolichol in the normal retina. Ziqiang Guan1, Y. Li2, 3, B. L. Lam2, 3, R. Wen2, 3. 1Biochemistry, Duke University, Durham, NC; 2Bascom Palmer Eye Institute, Miami, FL;3Ophthalmology, University of Miami Miller School of Medicine, Miami, FL 959—A0068 Experience and Treatment Patterns of Retinopathy Of Prematurity at a Tertiary Medical Center between 2002-2012. Abdul-Hadi Kaakour, E. D. Hansen, H. A. Aziz, R. Young, A. M. Berrocal. Bascom Palmer Eye Institute, Miami, FL 963—A0072 Fundus Hemorrhages in a Term Newborn and Preterm Population: Does Examination Timing Influence Findings?Darius M. Moshfeghi1, C. A. Ludwig1, N. F. Callaway2, 1. 1Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA; 2Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 965—A0074 Utility of Fluorescein Angiography for the Diagnosis and Management of Retinopathy of Prematurity (ROP). Karyn Jonas1, S. Patel1, M. A. Klufas1, M. Ryan2, M. P. Gupta1, S. Ostmo2, A. M. Berrocal3, M. A. MartinezCastellanos4, M. F. Chiang2, R. V. Chan1. 1Ophthalmology, Weill Cornell Medical College, New York, NY; 2Ophthalmology, Casey Eye Institute at Oregon Health and Science Univeristy, Portland, OR; 3Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 4Asociación para Evitar la Ceguera en México, Mexico City, Mexico 1060—B0194 Long-Term Evaluation of Visual Field Enhancement in Glaucomatous Eyes Following Surgical Intraocular Pressure Reduction. Iman Goharian1, J. Shaw1, S. K. Gardiner2, T. M. Wright1, D. S. Greenfield1. 1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, FL; 2Devers Eye Institute, Legacy Health, Portland, OR 1075—B0209 Combined Laser Ray Tracing and Optical Coherence Tomography system to measure changes in lens shape and on-axis and off-axis focal length with accommodation. Bianca Maceo Heilman1, 2, M. Ruggeri1, A. Gonzalez1, C. J. Rowaan1, A. Bernal3, E. Arrieta1, A. Ho4, F. Manns1, 2, J. A. Parel1, 5. 1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Miami, FL; 2Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, College of Engineering, University of Miami, Coral Gables, FL; 3Bioniko Consulting LLC, Sunny Isles Beach, FL; 4Brien Holden Vision Institute, Sydney, NSW, Australia; 5Vision Cooperative Research Centre, Brien Holden Vision Institute, University of New South Wales, Sydney, NSW, Australia 1125—D0027 Surface quality assessment of explanted keratoprostheses using confocal and scanning electron microscopy. Jean-Marie A. Parel1, 4, H. A. Durkee1, P. L. Blackwelder6, D. Miller5, A. Bermudez2, K. Sivaraman3, F. Cabot3, M. C. Aguilar1, V. L. Perez3, G. Amescua3. 1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Ocular Pathology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 3Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 4Brien Holden Vision Institute, UNSW, Sydney, NSW, Australia; 5Ocular Microbiology Laboratory, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 6University of Miami Center for Advanced Microscopy (UMCAM) and Marine Geosciences (RSMAS), University of Miami, Coral Gables, FL 1218—D0195 Outcomes of Vitrectomy for Vitreomacular Traction after an Initial Observation Period. Jonathan Tzu, H. W. Flynn, W. smiddy. Bascom Palmer Eye Institute, Miami, FL 1224—D0201 Clinical Results of Ocriplasmin For Symptomatic Vitreomacular Traction Syndrome. Anuj Chawla, J. Fortun. Ophthalmology, Bascom Palmer Eye Institute, West Palm Beach, FL 1236—D0213 Clinical Characteristics and Management of Full Thickness Macular Holes Following Vitrectomy for Vitreomacular Traction. Marco Gonzalez, H. W. Flynn, W. smiddy, C. Bokman. Bascom Palmer Eye Institute, Miami, FL Monday Papers/Minisymposium 1720— 11:45 Development of Choroidal Depigmentation in Birdshot Retinochoroidopathy Patients Treated with Fluocinolone Acetonide Implants. Blake Isernhagen1, H. Patel1, 6, S. Haug2, E. Cunningham3, F. Pichi5, C. Y. Lowder4, S. K. Srivastava4, J. L. Davis1. 1Ophthalmology, Bascom Palmer Eye Institute, Miami Beach, FL; 2West Coast Retina, San Francisco, CA; 3California Pacific Medical Center, San Francisco, CA; 4Cleveland Clinic, Cleveland, OH; 5San Giuseppe Hospital, University Eye Clinic, Milan, Italy; 6Retina Institute, Los Angeles, CA 2031— 4:30 Newborn Retinal Hemorrhages: One-year Results of the Newborn Eye Screening Test (NEST) Study. Natalia F. Callaway2, 1, C. Ludwig2, D. M. Moshfeghi2. 1Ophthalmology, Bascom Palmer Eye Institute, Chicago, IL;2Ophthalmology, Stanford University Byers Eye Institute, Stanford, CA Monday Posters 1377—A0072 Trends in Patient Satisfaction During Transition to Electronic Medical Records in the Pediatric Ophthalmology Clinic. Kara M. Cavuoto1, 2, P. Monsalve1, 2, J. C. Schiffman1, 2, T. C. Chang1, 2. 1Univ of Miami Sch of Medicine, Miami, FL; 2Bascom Palmer Eye Institute, Miami, FL 1383—A0078 Utilization of OphthalmologySpecific Emergency Department Services: A Prospective Study. Daniel Gologorsky, J. C. Schiffman, L. Ajuria, J. Banta. Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 1413—A0108 Long-term cigarette smoking causes histone overexpression in the retina. Gaofeng Wang1, 2, C. B. Gustafson1, A. Saab1, D. Van Booven1, W. Scott1. 1Hussman Inst for Human Genomics, Univ of Miami Miller Sch of Med, Miami, FL; 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 1465—A0160 Evaluation of macular microvasculature and blood flow velocities by non-invasive, high-resolution functional imaging in proliferative diabetic retinopathy. Thalmon R. Campagnoli1, G. M. Somfai1, 2, J. Tian1, W. smiddy1, D. DeBuc1. 1Bascom Palmer Eye Institute, Miami, FL; 2Ophthalmology, Semmelweis University, Budapest, Hungary 1466—A0161 Interactive Retinal Blood Flow Analysis of Macular Region using the Retinal Function Imager. Jing Tian, G. M. Somfai, D. DeBuc. Bascom Palmer Eye Institute, University of Miami, Miami, FL 1467—A0162 The assessment of blood flow velocities in retinal collateral and shunt vessels in diabetic retinopathy. Gabor M. Somfai2, 1, T. Campagnoli2, J. Tian2, W. smiddy2, D. DeBuc2. 1Department of Ophthalmology, Semmelweis University, Budapest, Hungary; 2Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL 1555—D0010 Assessment of corneal suturing performance using the Bioniko ophthalmic surgery models in inexperienced vs experienced ophthalmic surgeons. Florence Cabot1, P. Chhadva1, M. Joag1, M. C. Aguilar1, H. A. Durkee1, E. Arrieta1, J. A. Parel1, 2, S. H. Yoo1, C. L. Karp1. 1Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Brien Holden Vision Institute, University of New South Wales, Sydney, NSW, Australia 1619—D0127 Diagnostic value of entire vertical thickness profiles of epithelium and Bowman’s layer for subclinical keratoconus using ultra-high resolution optical coherence tomography. Meixiao Shen1, Z. Xu1, M. Peng1, J. Jiang1, J. Wang2, F. Lv1. 1Wenzhou Medical University, Wenzhou, China; 2Bascom Palmer Eye Institute, Miami, FL 1878—C0186 Combination Therapy for Candida Endophthalmitis: An in vitro study. Daniel Choi1, H. W. Flynn1, D. Miller1, B. D. Wilson2. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Ophthalmology, University of Miami School of Medicine, Miami, FL 1959—D0162 Noninvasive Quantitative Elastography of the Cornea and the Lens with Optical Coherence Elastography. Kirill Larin1, 2, M. D. Twa3, F. Manns4, S. Aglyamov5. 1University of Houston, Houston, TX; 2Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX; 3School of Optometry, University of Alabama, Birmingham, AL; 4Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Maimi, FL; 5Biomedical Engineering, University of Texas at Austin, Auston, TX 2241—B0094 Gene Expression Profiling Of Notch1 Positive Progenitor Cells Isolated From Developing Retina. Galina Dvoriantchikova1, I. Perea-Martinez1, D. Danek1, A. Barry1, S. Pappas1, X. Dvoriantchikova1, D. V. Ivanov1, 2.1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL; 2Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 2271—B0176 Effects of Mineralocorticoid Receptor Antagonist on Diabetic Retina Using Goto-Kakizaki Rat. Min Zhao1, 2, C. AndrieuSoler1, 2, E. bousquet1, 3, R. Levy1, 2, F. Halili4, A. Arboleda4, E. Rodríguez-Villagra5, I. BravoOsuna5, R. Herrero-Vanrell5, F. F. Behar-Cohen1, 6. 1Team 17, Inserm UMRS1138, Centre de Recherche des Cordeliers, Paris, France; 2University Paris Descartes, Sorbonne Paris Cité, UMRS 1138, Paris, France; 3Department of Ophthalmology, AP-HP, Hôtel-Dieu of Paris, Paris, France; 4Ophthalmic Biophysics Center, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 5Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain; 6Hôpital Ophtalmique Jules-Gonin, Lausanne, Switzerland 2287—B0192 HC-HA/PTX3, an active matrix component of amniotic membrane, inhibits proliferation and epithelial mesenchymal transition of RPE cells: a potential novel therapy for PVR. Ajay E. Kuriyan1, H. He2, E. Arrieta1, V. Sargent1, Y. Zhu2, C. Su2, N. Batra1, H. W. Flynn1, J. A. Parel1, S. C. Tseng2. 1Bascom Palmer Eye Institute, Univ of Miami/Miller School of Medicine, Miami, FL; 2TissueTech, Inc., Ocular Surface Center, and Ocular Surface Research Education Foundation, Miami, FL 2399—C0049 Characterization of Mesdc2 as a novel RPE phagocytosis ligand. Xiuping Chen1, 2, F. Guo1, Y. Ding1, A. K. Shakya1, W. Li1. 1Ophthalmology, Bascom palmer eye institutionUniversity of Miami, Miami, FL;2Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai, China 2445—C0095 Role of Focal Adhesion Kinase (FAK) in RGC in Glaucoma. M Livia Bajenaru1, A. R. Santos1, K. K. Park2, S. R. Dubovy1, A. Bermudez1. 1Miller School of Medicine, Univ of Miami, Bascom Palmer Eye Inst, Miami, FL; 2The Miami Project to Cure Paralysis, Miller School of Medicine, Univ of Miami, Miami, FL 2505—D0109 Meibomian gland dysfunction and hypercholesterolemia. Yousef A. Alghamdi2, 1, N. M. Shalabi2, 1, A. L. McClellan2, 1, A. Galor2, 1. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Ophthalmology, Miami Veterans Administration Medical Center, Miami, FL Tuesday Papers/Minisymposium 2607— 9:30 Macular Retinal Sublayer Thickness Changes in Patients and Carriers in the Natural History Phase of the Leber Hereditary Optic Neuropathy G11778A Gene Therapy Clinical Trial. Byron L. Lam, S. P. Burke, M. X. Wang, G. A. Nadayil, G. Gregori, W. J. Feuer, P. R. Rosa, S. Cuprill-Nilson, R. Vandenbroucke, J. Guy. Bascom Palmer Eye Institute, University of Miami, Miami, FL 2608— 9:45 Leber Hereditary Optic Neuropathy Gene Therapy (LHON) Clinical Trial: Initial Results. John Guy1, W. J. Feuer1, V. Porciatti1, W. W. Hauswirth2, J. L. Davis1, B. L. Lam1, R. D. Koilkonda1, H. Yuan1, P. Gonzalez1, A. Lalwani1. 1Bascom Palmer Eye Institute, Miami, FL; 2Ophthalmology, University of Florida, Gainesville, FL 3178— 11:30 Patterns of early glaucomatous visual field loss and their evolution over time. Tobias Elze1, 2, L. Q. Shen3, J. L. Wiggs3, M. V. Boland4, S. Wellik5, P. J. Bex6, L. R. Pasquale3. 1Harvard Medical School, Schepens Eye Research Institute, Boston, MA; 2Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany; 3Mass. Eye and Ear Infirmary, Harvard Medical School, Boston, MA; 4Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD; 5Bascom Palmer Eye Institute, Miami, FL; 6Northeastern University, Boston, MA 3516— 4:45 Retinal Detachment in a Pediatric Population: A Retrospective Review of Etiology and Outcome. Sarah Read, H. A. Aziz, R. Young, T. G. Murray, H. W. Flynn, A. M. Berrocal. Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 3530— 4:45 Quantification of 16S Bacteria and Torque Teno Virus in Dry Eye Syndrome and Clinical Correlations. Cecilia S. Lee1, A. Galor2, 3, A. I. Tuzhikov2, V. I. Shestopalov2, R. Van Gelder1. 1Ophthalmology, University of Washington, Seattle, WA; 2Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 3Miami Veterans Affairs Healthcare, Miami, FL Tuesday Posters 2668—A0236 Conjunctival cyst in the setting of Baerveldt glaucoma implant: Clinicopathologic correlation of three cases. Antonio Bermudez2, 1, M. Fernandez2, R. K. Parrish3, S. R. Dubovy2. 1Ophthalmology, Instituto de Oftalmologia Conde de Valenciana, Mexico City, Mexico; 2Florida Lions Ocular Pathology Laboratory, Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine, Miami, FL; 3Ophthalmology, Bascom Palmer Eye Insitute, Miami, FL 2702—A0270 3-Year Outcomes of Glaucoma Drainage Device Surgery in Eyes With and Without Prior Conjunctival Incisional Surgery. Tracy M. Wright, I. Goharian, W. J. Feuer, W. Shi, D. S. Greenfield. Ophthalmology, Bascom Palmer Eye Institute, Palm Beach Gardens, FL 2735—B0020 Surgical Outcomes of Congenital Glaucoma in Peters’Anomaly. Elena Bitrian1, A. L. Grajewski2. 1Ophthalmology, University of Minnesota, Minneapolis, MN; 2Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 2736—B0021 Hypotony maculopathy after trabeculectomy: outcomes of bleb revision and choroidal drainage. Cheng Zhou1, E. Bitrian3, M. M. Wright3, A. L. Grajewski2. 1University of Minnesota Medical School, Saint Paul, MN;2Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 3Ophthalmology, University of Minnesota, Minneapolis, MN 2759—B0081 Quantitative Analysis of Retinal Blood Flow in Normal and Glaucoma by Doppler Fourier-Domain Optical Coherence Tomography. Sowmya Srinivas1, M. Nittala1, O. Tan2, R. Varma3, B. A. Francis1, D. S. Greenfield4, R. K. Parrish4, J. S. Schuman5, S. R. Sadda1, D. Huang2. 1Ophthalmology, Doheny Eye Institute, Los Angeles, CA; 2Ophthalmolgy, Casey Eye Institute, Portland, OR; 3Ophthalmology, University of Southern California, Los Angeles, CA; 4Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, FL; 5Department of Ophthalmology, UPMC Eye Center,University of Pittsburgh, Pittsburgh, PA 2782—B0164 WidefieldEn face Swept Source OCT Imaging of Geographic Atrophy, Retinal Pigment Epithelial Detachments, and Macular Hemorrhages. Brian E. Goldhagen1, J. E. Legarreta1, A. D. Legarreta1, E. R. Ramenaden1, K. Schaal1, P. F. Stetson2, M. Cai2, M. Laron2, G. Gregori1, P. J. Rosenfeld1. 1Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Research and Development, Carl Zeiss Meditec, Inc, Dublin, CA 2789—B0171 WidefieldEn face Swept Source OCT Imaging of Dry Age-Related Macular Degeneration Subretinal Drusenoid Deposits. Andrew D. Legarreta1, K. Schaal1, J. E. Legarreta1, Q. Cheng1, E. R. Ramenaden1, B. E. Goldhagen1, M. Cai2, M. Laron2, G. Gregori1, P. J. Rosenfeld1. 1Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Research and Development, Carl Zeiss Meditec, Inc, Dublin, CA 2794—B0176 WidefieldEn face OCT imaging of Subretinal Drusenoid Deposits. Karen Schaal1, A. Legarreta1, G. Gregori1, J. Legarreta1, Q. Cheng1, P. F. Stetson2, M. Cai2, M. Laron2, M. K. Durbin2, P. J. Rosenfeld1. 1Basom Palmer Eye Institute, Key Biscayne, FL; 2Carl Zeiss Meditec, Inc., Dublin, CA*CR 2803—B0185 En-Face Imaging of Microcysts in Macular Teleangiectasia Type 2 Using Minimum- and MeanIntensity Projections. Paul F. Stetson1, J. Legarreta2, A. D. Legarreta2, M. R. Thorell2, G. Gregori2, P. J. Rosenfeld2. 1Carl Zeiss Meditec, Dublin, CA; 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 2818—C0046 Inverse Association Between L-DOPA and Age-Related Macular Degeneration. Kamyar Vaziri1, S. G. Schwartz1, T. B. Connor2, A. A. Moshfeghi3, D. M. Moshfeghi4, K. S. Kishor1, H. W. Flynn1, J. Carroll2, M. Brilliant5, B. S. McKay6. 1Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Ophthalmology, Medical College of Wisconsin, Milwaukee, WI; 3Ophthalmology, Retina Associates of Kentucky, Lexington, KY;4Ophthalmology, Stanford Byers Eye Institute, Palo Alto, CA; 5Laboratory of Genetics, University of Wisconsin, Marshfield, WI; 6Ophthalmology and Vision Science, University of Arizona, Tuscon, AZ 2845—C0073 Association between growth of geographic atrophy (GA) and the complement factor I (CFI) Locus. Zohar Yehoshua1, C. de Amorim Garcia Filho1, R. Portella Nunes1, 5, G. Gregori1, F. M. Penha1, A. A. Moshfeghi4, 1, K. Zhang2, S. R. Sadda3, W. J. Feuer1, P. J. Rosenfeld1. 1Bascom Palmer Eye Institute, University of Miami, Miami, FL; 2Shiley Eye Center, University of California, San Diego, La Jolla, CA; 3Doheny Eye Center, Los Angeles, CA; 4University of Southern California, Los Angeles, CA; 5Department of Ophthalmology and Visual Science, Paulista School of Medicine, Sao Paulo, Brazil 2968—D0090 Accuracy of Intraoperative Wavefront Aberrometer for Toric IOL in Post Refractive Eyes Undergoing Cataract Surgery. Nilufer Yesilirmak, S. Palioura, V. Diakonis, D. Waren, S. H. Yoo, K. Donaldson. Cornea, Bascom Palmer Eye Institute, Miami, FL 3020—D0185 Long-term outcomes of intrastromal ring segments for pediatric keratoconus. Julia Y. Kang2, F. Cabot2, 1, V. Kankariya3, S. H. Yoo2, 1. 1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Miami, FL; 2Medical School, University of Miami Miller School of Medicine, Miami, FL; 3Asian Eye Hospital and Laser Institute, Pune, India 3048—D0244 Minor Ipsilateral Simple Limbal Epithelial Transplantation (Mini-SLET) for Pterygium Treatment. Erick HernandezBogantes1, A. J. Ramirez-Miranda1, G. Amescua2, A. Navas1, A. Abdala-Figuerola1, A. G. OlivoPayne1, E. O. Graue1. 1Cornea and Refractive Surgery, Conde de Valenciana, Mexico City, Mexico; 2Cornea and Refractive Surgery, Bascom Palmer Eye Institute, Miami, FL 3055—D0251 Inflammatory manifestations of Ocular Graft versus Host Disease in the Cornea, Eyelid and Conjunctiva. Stephanie Duffort1, H. Barreras2, R. Levy2, 1, V. L. Perez1, 2. 1Ophthalmology, Bascom Palmer Eye Institut, Miami, FL; 2Immunology and Microbiology, University of Miami Miller School of Medicine, Miami, FL 3139—D0335 “Spotless” Birdshot Chorioretinopathy: Improved Diagnostic Sensitivity with Indocyanine Green Angiography. Christopher R. Henry1, A. K. Reddy2, M. A. Gonzalez1, S. Yeh3, T. A. Albini1. 1Bascom Palmer Eye Institute, Miami Beach, FL; 2Ophthalmology, University of Virginia, Charlottesville, VA; 3Ophthalmology, Emory University, Atlanta, GA 3254—A0174 Direct interaction of cochlin with mechanosensing channel TREK-1 in intraocular pressure regulation. Teresia Carreon1, C. Piqueras1, A. Castellanos2, X. Gasull2, S. K. Bhattacharya1. 1Ophthalmology, University of Miami Bascom Palmer Eye Institute, Miami, FL; 22. Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain 3272—A0192 Quantification of cochlin in DBA/2J mice in vivo using optical coherence tomography. Sanjoy K. Bhattacharya, T. Carreon, A. Aljohani, G. Gregori, J. Wang. Bascom Palmer Eye Institute, Univ of Miami Miller Sch of Med, Miami, FL 3318—B0101 OCT Angiography (OCTA) in Healthy Human Subjects. Jack Yi1, D. Matsunaga1, J. E. Legarreta2, A. D. Legarreta2, G. Gregori2, M. K. Durbin3, U. Sharma3, P. J. Rosenfeld2, C. A. Puliafito1, A. H. Kashani1. 1USC Eye Institute, Keck School of Medicine of USC, Los Angeles, CA; 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 3Advanced Development, Carl Zeiss Meditec, Inc., Dublin, CA 3334—B0117 OCT Angiography (OCTA) of Macular Neovascularization (MNV). Emeline R. Ramenaden1, J. E. Legarreta1, A. D. Legarreta1, D. Matsunaga2, A. H. Kashani2, G. Gregori1, Q. Zhang3, R. K. Wang3, C. A. Puliafito2, P. J. Rosenfeld1. 1Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2USC Eye Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; 3Bioengineering, University of Washington, Seattle, WA 3335—B0118 OCT Angiography (OCTA) of Diabetic Retinopathy. Douglas Matsunaga1, J. Yi1, L. C. Olmos1, J. Legarreta3, A. D. Legarreta3, G. Gregori3, U. Sharma2, P. J. Rosenfeld3, C. A. Puliafito1, A. H. Kashani1. 1USC Eye Center, Keck School of Medicine of USC, Los Angeles, CA; 2Research and Development, Carls Zeiss Meditec, Dublin, CA; 3Bascom Palmer Eye Institute, Miami, FL 3356—B0139 OCT Angiography (OCTA) of Macular Telangiectasia Type 2. John E. Legarreta1, A. D. Legarreta1, M. R. Thorell1, Q. Zhang2, G. Gregori1, D. Matsunaga3, A. H. Kashani3, R. K. Wang2, C. A. Puliafito3, P. J. Rosenfeld1.1Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Bioengineering, University of Washington, Seattle, WA; 3USC Eye Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 3364—B0147 Conjunctival blood flow velocity in patients with retinal vasculitis assessed with the retinal function imager. Nicole Stuebiger1, A. Tao2, 3, W. Lee2, S. Pineda2, H. Jiang2, J. Wang2, J. L. Davis2, D. DeBuc2. 1Department of Ophthalmology, Charite, University Medicine Berlin, Berlin, Germany; 2Department of Ophthalmology, University of Miami, Bascom Palmer Eye Institute, Miami, FL; 3Ophthalmology and Optometry, School of Wenzhou Medical College, Wenzhou, China 3424—C0235 Orbital Invasion From Ocular Surface Squamous Neoplasia. Benjamin P. Erickson1, A. Galor2, T. Johnson1, W. W. Lee1, C. L. Karp2. 1Oculoplastics, Bascom Palmer Eye Institute, Miami, FL; 2Cornea, Bascom Palmer Eye Institute, Maim, FL 3607—A0036 Dynamics of retinal ganglion cell plasticity induced by deficiency of targetderived factors in the mouse. Vittorio Porciatti, M. J. Rojas, T. Chou, R. Wen. Bascom Palmer Eye Inst, Univ of Miami Miller Sch Med, Miami, FL 3758—B0247 Thickness maps of the macular intra retinal layers and the choroid using optical coherence tomography in myopic eyes. Ye Yang1, M. Shen2, J. Wang3, S. Huang2. 1Special Examination Centre, Eye Hospital, Wenzhou, China; 2Special Examination Centre, Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China; 3Bascom Palmer Eye Inst Lib, Miami, FL 3853—C0215 Hemorrhagic Occlusive Retinal Vasculitis after Cataract Extraction: AVancomycin-Associated Reaction? Michelle M. Kron-Gray1, A. J. Witkin2, D. Witkin2, C. R. Baumal2, R. E. Engstrom3, T. A. Albini6, I. R. Batlle4, D. Eliott5, M. W. Johnson1, A. Shah1. 1Ophthalmology, University of Michigan, Dexter, MI; 2Ophthalmology, Tufts University, Boston, MA; 3Jules Stein Eye Institute, Los Angeles, CA; 4Retina Associates PA, Shawnee Mission, KS; 5Massachusetts Eye and Ear Infirmary, Boston, MA; 6Bascom Palmer Eye Institute, Miam, FL Wednesday Papers/Minisymposium 4320— 11:30 Practice patterns in retinopathy of prematurity (ROP) treatment for disease milder than recommended by published guidelines. Michael F. Chiang1, M. Patel2, R. Anzures2, S. Ostmo3, K. Jonas2, K. A. Drenser4, A. M. Berrocal5, C. Simmons6, R. V. Chan2. 1Ophthalmology and Medical Informatics, Oregon Health & Science University, Portland, OR; 2Ophthalmology, Weill Cornell Medical College, New York, NY; 3Ophthalmology, Oregon Health & Science University, Portland, OR; 4Ophthalmology, William Beaumont Hospital, Royal Oak, MI; 5Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 6Pediatrics, Cedars Sinai Medical Center, Los Angeles, CA 4334— 11:45 Tumor diameter contributes prognostic information that enhances the accuracy of gene expression profile molecular classification in uveal melanoma. Scott Walter1, D. L. Chao2, J. C. Schiffman1, W. J. Feuer1, J. Harbour1, 3. 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL; 2Department of Ophthalmology, UCSF School of Medicine, San Francisco, CA; 3Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 4361— 11:30 A diet supplemented with grapes preserves photoreceptor function in mouse models of retinal degeneration. Maria Esperanza E. Rodriguez Escalante, T. Lee, A. Davis, A. K. Patel, A. Hackam. Bascom Palmer Eye Institute, University of Miami, Miami, FL 4364— 12:15 Protection of pattern electroretinogram (PERG) by oncostatin M after optic nerve injury in mice. Rong Wen1, X. Xia2, T. Chou1, Y. Li1, V. Porciatti1. 1Bascom Palmer Eye Institute, University of Miami, Miami, FL; 2Department of Ophthalmology, Shanghai First Peoples Hospital, Shanghai Jiao Tong University, Shanghai, China 4367— 11:15 Optical coherence photoacoustic microscopy for in vivomultimodal retinal imaging. Tan Liu1, X. Liu1, R. Wen2, Y. Li2, C. A. Puliafito3, H. F. Zhang4, S. Jiao1. 1Biomedical Engineering, Florida International University, Miami, FL; 2Bascom Palmer Eye Institute, University of Miami, Miami, FL; 3Keck School of Medicine, University of Southern California, Los Angeles, CA; 4Biomedical Engineering, Northwestern University, Evanston, IL 4431—A0057 Dry eye profiles in patients with a positive elevated surface matrix metallopeptidase 9 point of care test versus negative patients. Allister Gibbons1, N. Lanza2, F. Valenzuela1, V. L. Perez1, A. Galor1, 3. 1Bascom Palmer Eye Institute, Miami, FL; 2University of Miami, Miller School of Medicine, Miami, FL; 3Ophthalmology, Veterans Affairs Hospital, Miami, FL 4557—B0110 Reflectance Spectrum and Birefringence of Retinal Nerve Fiber Layer in Hypertensive Retinas. Xiang-Run Huang1, 2, Y. Z. Spector2, 1, M. Castellanos1. 1Bascom Palmer Eye Institute, University of Miami, Miami, FL;2Department of Biomedical Engineering, University of Miami, Miami, FL 4736—D0181 Ablative fractional laser resurfacing with laser-assisted delivery of 5-fluorouracil: a novel nonsurgical treatment for cicatricial ectropion. Alexandra E. Levitt1, B. Lee2, A. C. Ko1, W. W. Lee1. 1Bascom Palmer Eye Institute, Miami, FL; 2Shiley Eye Center, San Diego, CA 4804— 4:45 A Phase 1 Safety Study of an Orally Available Tyrosine Kinase Inhibitor X-82 in Previously Treated Wet AMD Patients. Philip J. Rosenfeld1, J. S. Slakter2, D. S. Boyer3, D. M. Brown4, N. A. Chaudhry5, M. J. Elman6, S. S. Patel7, D. O’Shaughnessy8. 1Bascom Palmer Eye Institute, Univ of Miami Miller Sch of Med, Miami, FL; 2Digital Angiographic Reading Center, New York, NY; 3Retina-Vitreous Associates Medical Group, Beverly Hills, CA, CA; 4Retina Consultants of Houston, Houston, TX; 5New England Retina Associates, Guilford, CT; 6Elman Retina Group, Baltimore, MD; 7Retina Research Institute of Texas, Abilene, TX; 8Xcovery Vision Inc, West Palm Beach, FL Wednesday Posters 4035—A0162 Functional consequences of Mpzl3knockout in the ocular surface of mice. Alexander S. Barsam1, Y. Wang1, A. Reyes-Capo1, M. Urbieta1, H. Mitchell2, T. Cao Wikramanayake2, V. L. Perez1. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Dermatology, University of Miami Miller School of Medicine, Miami, FL 4046—A0223 Photodynamic therapy to treat Methicillin-Resistant Staphylococcus Aureus (MRSA) keratitis: An in vitro study. Heather A. Durkee1, F. Halili1, M. Taneja2, D. Miller3, 4, A. Arboleda1, C. J. Rowaan1, M. C. Aguilar1, G. Amescua4, H. W. Flynn4, J. A. Parel1, 5. 1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2LV Prasad Eye Institute, Hyderabad, India; 3Ocular Microbiology Laboratory, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 4Anne Bates Leach Eye Hospital, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 5Brien Holden Vision Institute, UNSW, Sydney, NSW, Australia 4074—A0251 Gram-negative Isolates from Patients with Endophthalmitis: Incidence Rates and Antibiotic Susceptibilities. Benjamin D. Wilson, D. Miller, H. W. Flynn. Bascom Palmer Eye Institution, Miami, FL 4077—A0254 Microbiology and Biofilm Growth on Clinically Infected Silicone Implants within the Lacrimal System: A Thirty Year Review. Lilangi S. Ediriwickrema1, D. Samimi2, 1, B. Bielory2, D. Miller2, T. V. Johnson2.1Ophthalmology, USC Eye Institute, Los Angeles, CA; 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 4088—B0010 Evaluation of a Surgical Microscope Interfaced SD-OCT system for Anterior Segment Surgery. Marco Ruggeri1, F. Cabot1, S. H. Yoo1, J. A. Parel1, 2. 1Ophthalmology, Bascom Palmer Eye Inst, Univ of Miami, Miami, FL;2Vision Cooperative Research Centre, Brien Holden Vision Institute, UNSW, Sydney, NSW, Australia 4104—B0026 Smartphone fundus photography, in vivo retinal fluorescent photography and fluorescein angiography in mouse eyes. Cynthia X. Qian1, E. Hasegawa1, L. Haddock2, D. M. Wu1, 3, S. Mukai1. 1Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA; 2Bascom Palmer Eye Institute, Palm Beach Gardens, FL; 3Genetics, Harvard Medical School, Boston, MA 4182—C0065 Combination Antifungal (intravitreal amphotericin-B and intravitreal voriconazole - AmB-Vo Regime) Therapy in treating filamentous fungal endophthalmitis at a tertiary eye care centre from South India. Nidhi Batra1, 2, A. Pathengay2, K. Mithal2, A. Jindal2, D. Vira2, N. Koday2, H. W. Flynn1. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Retina, LV Prasad Eye Institute, Visakhapatnam, India 4185—C0068 Endophthalmitis caused by nontuberculous Mycobacteria. Milan Shah1, N. Batra2, A. E. Kuriyan2, D. Parke3, J. L. Davis2, D. Miller2, H. W. Flynn2, T. A. Albini2. 1Midwest Eye Institute, Indianapolis, IN; 2Bascom Palmer Eye Institute, Univ of Miami/Miller School of Medicine, Miami, FL; 3VitreoRetinal Surgery, PA, Minneapolis, MN 4191—C0074 Endophthalmitis Associated with Glaucoma Drainage Implants. Carlos A. Medina Mendez, M. Butler, T. A. Albini, W. Smiddy, S. Gedde, D. Miller, H. W. Flynn. Bascom Palmer Eye Institute, Miami, FL 4193—C0076 Current Endophthalmitis Incidence Rates After Intravitreal Anti-VEGF Injections and Outcomes of Treatment. Harry W. Flynn, N. Gregori, A. A. Moshfeghi, P. J. Rosenfeld, S. G. Schwartz, J. Fortun, J. L. Kovach, K. Vaziri, T. A. Albini. Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 4229—C0238 Cigarette smoke-related hydroquinone decreases C1q expression through ROS production in the RPE. Maria E. Marin Castano1, M. J. Marin Carcia1, S. Recalde2, M. Hernandez2, A. Garcia Layana2. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Ophthalmology, Universidad de Navarra, Pamplona, Spain 4246—C0255 Glutathione S-Transferase Pi Isoform (GSTP1) Modulation by Sulforaphane Protects Human Retinal Pigment Epithelial Cells against Oxidative Stress. Wen-Hsiang Lee. Ophthalmology, Bascom Palmer Eye Institute - University of Miami, Miami, FL 4313—D0247 Automated Photosensitivity Assessment in Achromatopsic and Healthy Subjects. Mariela C. Aguilar1, A. Gonzalez1, C. J. Rowaan1, P. R. Rosa2, K. Alawa1, B. L. Lam2, J. A. Parel1, 3. 1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 3Brien Holden Vision Institute, UNSW, Sydney, NSW, Australia 4445—A0071 Incomplete response to artificial tears is associated with selfreported features of neuropathic ocular pain. Hatim Batawi1, 2, R. Levitt1, 7, E. Felix1, 3, T. P. Margolis4, C. Sarantopoulos1, 7, E. R. Martin5, 6, A. Galor1, 2.1Ophthalmology, Miami Veterans Administration Medical Center, Miami, FL; 2Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL; 3Department of Physical Medicine and Rehabilitation, University of Miami Miller School of Medicine, Miami, FL; 4Ophthalmology, Washington University School of Medicine, St Louis, MO; 5John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL; 6John T Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL; 7Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL 4574—B0127 Longitudinal and CrossSectional Analyses of Age and Intraocular Pressure Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness. Xinbo Zhang2, B. A. Francis5, O. Tan2, R. Varma4, D. S. Greenfield1, J. S. Schuman3, N. A. Loewen3, M. Sehi1, D. Huang2. 1Bascom Palmer Eye Institute, University of Miami, Miami, FL; 2Casey Eye Institute, Oregon Health & Science University, Portland, OR; 3University of Pittsburgh, Pittsburgh, PA;4Ophthalmology, University of Southern California, Los Angeles, CA; 5Doheny Eye Institute, Los Angeles, CA 4575—B0128 Area and volume analysis of the superior and inferior retinal nerve fiber layer (rNFL) bundles from SD-OCT thickness maps: description of the methodology. Samuel Burke4, W. J. Feuer1, S. Gedde1, R. K. Parrish1, J. Mwanza2, D. L. Budenz2, G. Triolo1, 3, P. Monsalve1, M. J. Rojas5, L. E. Vazquez1. 1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 2University of North Carolina, Chapel Hill, NC; 3Ophthalmology, University Scientific Institute San Raffaele, Milan, Italy; 4University of Miami Miller School of Medicine, Miami, FL; 5Department of Ophthalmology, Eastern Virginia Medical School, Norfolk, VA 4576—B0129 Area and volume analysis of the superior and inferior retinal nerve fiber layer (rNFL) bundles from SD-OCT thickness maps: detection of early, moderate, and severe glaucoma. Luis E. Vazquez1, W. J. Feuer1, J. Mwanza2, D. L. Budenz2, G. Triolo1, 3, P. Monsalve1, S. Gedde1, R. K. Parrish1. 1Ophthalmology, University of Miami Bascom Palmer Eye Institute, Miami, FL; 2Ophthalmology, University of North Carolina, Chapel Hill, NC; 3Ophthalmology, University Scientific Institute San Raffaele, Milan, Italy 4577—B0130 Area and volume analysis of the superior and inferior retinal nerve fiber layer (rNFL) bundles from SD-OCT thickness maps: correlation with thickness of the corresponding rNFL and ganglion cell-inner plexiform layer (GCIPL) sectors. Fred Chu1, W. J. Feuer1, J. Mwanza2, D. L. Budenz2, G. Triolo1, P. Monsalve1, R. K. Parrish1, S. Gedde1, L. E. Vazquez1. 1Bascom Palmer Eye Institute, Miami, FL; 2University North Carolina, Chapel Hill, NC 4579—B0132 Relationship between the Peripapillary Choroidal Thickness and Retinal Nerve Fiber Layer Thickness: A Population-based Study. Preeti Gupta1, 2, J. Tian3, P. Marziliano4, C. Y. Cheung1, 2, B. Mani1, 2, E. L. Lamoureux1, G. Cheung1, T. Aung1, 2, T. Y. Wong1, 2, C. Cheng1, 2. 1Ophthalmology, Singapore Eye Research Institute, Singapore, Singapore; 2Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore, Singapore; 3Department of Ophthalmology for the University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, Miami, FL; 4School of Electrical and Electronic Engineering Division of Information Engineering, Nanyang Technological University, Singapore, Singapore 4632—D0007 Construction Of Conditional Over-Expression Transgenic Model of Casein Kinase 1 Epsilon, A Potential Therapeutic Target For Dry AMD. George Inana1, C. Murat1, W. An1, M. McLaren2. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Graymatter Research, Miami, FL*CR 4948—B0147 Pannexin 1 expression in macroglia modulates their activation after optic nerve crush. Caitlin Mac Nair1, 2, C. Schlamp1, V. I. Shestopalov3, R. W. Nickells1. 1Ophthalmology and Visual Sciences, University of Wisconsin - Madison, Madison, WI; 2Cellular and Molecular Pathology Graduate Program, University of Wisconsin Madison, Madison, WI; 3Bascom Palmer Eye Institute, University of Miami, Miami, FL 5042—C0078 Visual and Anatomic Outcomes of Epiretinal Membrane Peeling after Previous Complex Rhegmatogenous Retinal Detachment Repair. Angelica Ortiz1, C. Y. Weng2, N. Gregori3, 4. 1University of Miami Miller School of Medicine, Miami, FL; 2Ophthalmology, Baylor College of Medicine, Houston, TX; 3Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 4Ophthalmology, Miami Veterans Affairs Medical Center, Miami, FL 5054—C0090 Ganglion cell layer thickness and visual improvement after epiretinal membrane surgery. Su Jeong Song1, W. smiddy2. 1ophthalmology, kangbuk samsung hospital, Seoul, Korea (the Republic of); 2Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 5136—C0200 Ultrahigh speed OCT angiography in age-related macular degeneration using swept source optical coherence tomography. Eric Moult1, 2, N. K. Waheed3, W. Choi2, M. Adhi3, T. de Carlo3, B. Potsaid4, V. Jayaraman5, P. J. Rosenfeld6, J. S. Duker3, J. G. Fujimoto2. 1Health Sciences and Technology, Harvard-MIT, Cambridge, MA; 2Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA; 3New England Eye Center, Tufts University Medical Center, Boston, MA; 4Advanced Imaging Group, Thorlabs, Inc, Newtown, MA; 5Praevium Research Inc., Santa Barbara, CA; 6Department of Ophthalmology, University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, Miami, FL 5150—C0214 Reticular Pseudodrusen, Enlarging Geographic Atrophy, and Decreased Choroidal Thickness in Age-Related Macular Degeneration. Mariana Rossi Thorell1, R. Goldhardt1, R. Portella Nunes2, C. de Amorim Garcia Filho2, G. Gregori1, Z. Yehoshua1, W. J. Feuer1, S. R. Sadda3, P. J. Rosenfeld1. 1Bascom Palmer Eye Institute, Miami, FL; 2Federal University of Sao Paulo - UNIFESP, Sao Paulo, Brazil; 3Doheny Eye Institute, Los Angeles, CA 5155—C0219 Widefield Choroidal Thickness Maps in Dry Age Related Macular Degeneration with and without Reticular Pseudodrusen. Giovanni Gregori, A. D. Legarreta, K. Schaal, J. E. Legarreta, B. E. Goldhagen, E. R. Ramenaden, Z. Yehoshua, P. J. Rosenfeld. Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 5160—C0224 Choroidal thickness in eyes with central geographic atrophy secondary to Stargardt disease and agerelated macular degeneration. Renata Portella Nunes1, 2, P. R. Rosa1, R. Goldhardt1, M. Rossi Thorell1, G. Gregori1, W. J. Feuer1, B. L. Lam1, G. Staurenghi3, P. J. Rosenfeld1. 1Bascom Palmer Eye Institute, Florianopolis, Brazil; 2Ophthalmology and Visual Sciences department, Paulista School of Medicine, São Paulo, Brazil; 3Deptartment of Clinical Science - Luigi Sacco, University of Milan, Milan, Italy 5219—D0224 Role of Strabismus Surgery in the Treatment of Adult-Onset Esotropia. Sara Grace, K. M. Cavuoto, H. Capo, W. Shi. Ophthalmology, Bascom Palmer Eye Institute, Miami, FL Wednesday Workshop 4632—D0007 Construction Of Conditional Over-Expression Transgenic Model of Casein Kinase 1 Epsilon, A Potential Therapeutic Target For Dry AMD. George Inana1, C. Murat1, W. An1, M. McLaren2. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Graymatter Research, Miami, FL Thursday Posters 5295—A0049 Imaging rhodopsin molecular contrast in vivo by optical coherence tomography. Shuliang Jiao1, T. Liu1, B. L. Lam2, R. Wen2. 1Biomedical Engineering, Florida International University, Miami, FL; 2Bascom Palmer Eye Institute, Miami, FL 5328—A0177 Rates of Sample Acquisition in Uveal Melanoma Fine Needle Aspiration Biopsies Using Transscleral and Transvitreal Techniques. Amy C. Schefler1, 2, M. E. Bretana1, P. ChevezBarrios2, B. Teh2, N. Nikpoor3, D. Gologorsky3. 1Ophthalmology, Retina Consultants of Houston, Houston, TX; 2Ophthalmology, Houston Methodist Hospital, Houston, TX; 3Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 5328—A0177 Rates of Sample Acquisition in Uveal Melanoma Fine Needle Aspiration Biopsies Using Transscleral and Transvitreal Techniques. Amy C. Schefler1, 2, M. E. Bretana1, P. ChevezBarrios2, B. Teh2, N. Nikpoor3, D. Gologorsky3. 1Ophthalmology, Retina Consultants of Houston, Houston, TX; 2Ophthalmology, Houston Methodist Hospital, Houston, TX; 3Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 5358—A0207 Low luminance vision improves nearly twice as much as standard vision with ranibizumab for neovascular age-related macular degeneration. Ronald E. Frenkel1, 2, A. E. Fung3, H. Shapiro3, I. Stoilov3. 1Bascom Palmer Eye Institute, Miami, FL; 2East Florida Eye Institute, Stuart, FL; 3Genentech, Inc., South San Francisco, CA 5362—A0211 Visual acuity impairment under low luminance conditions at baseline is a powerful predictor of visual acuity response to ranibizumab therapy in patients with neovascular age-related macular degeneration. Marc C. Peden1, 2, R. E. Frenkel3, 4, H. Shapiro5, I. Stoilov5. 1Retina Associates of Florida, Tampa, FL; 2Department of Ophthalmology, University of Florida, Gainesville, FL; 3Bascom Palmer Eye Institute, Miami, FL; 4East Florida Eye Institute, Stuart, FL;5Genentech, Inc., South San Francisco, CA 5405—A0254 ERG preservation by intravitreal injected recombinant mesencephalic astrocyte-derived neurotrophic factor(MANF) in rd10 mice. Yiwen Li, R. Wen. Bascom Palmer Eye Institute, University of Miami, Miami, FL 5484—B0043 ABCF1 extrinsically regulates retinal pigment epithelial cell phagocytosis. Feiye Guo1, Y. Ding1, N. B. Caberoy2, F. Wang3, R. Chen3, W. Li1. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2School of Life Sciences, University of Nevada Las Vegas, Las Vegas, NV; 3Dept. of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX 5531—B0102 Phosphatase and Tensin Homolog (PTEN) Knockout in Retinal Ganglion Cells (RGCs) Rescues Optic Neuritis in Experimental Autoimmune Encephalomyelitis (EAE) Mice. Venu Talla1, V. Chiodo2, V. Porciatti1, S. L. Boye2, W. W. Hauswirth2, J. Guy1. 1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Department of Ophthalmology, University of Florida, Gainesville, FL 5891—A0062 Rescue of transgenic mice expressing human G11778AND4. Hong Yu, J. Guy. Ophthalmology, Bascom Palmer Eye Inst, Univ of Miami, Miami, FL 5998—B0147 Anatomically-accurate paraxial optical model of cynomolgus lens accommodation with continuous gradient. Fabrice Manns1, 2, B. Maceo Heilman1, 2, A. Ho3, 1, J. A. Parel1, 4. 1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami, Miami, FL; 2Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami, Coral Gables, FL; 3Brien Holden Vision Institute, Sydney, NSW, Australia; 4Vision Cooperative Research Center, Sydney, NSW, Australia 6000—B0149 Isolated human lens shape determined by tridimensional digital shadowphotogrammetry: A pilot study. Ashik Mohamed1, 2, H. A. Durkee3, F. Manns3, 4, A. Ho2, 5, V. S. Sangwan1, 5, J. A. Parel3, 5, R. C. Augusteyn2, 5. 1Prof. Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, India; 2School of Optometry and Vision Science, The University of New South Wales, Sydney, NSW, Australia; 3Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; 4Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami College of Engineering, Miami, FL; 5Vision Cooperative Research Centre, Brien Holden Vision Institute, Sydney, NSW, Australia 6004—B0153 Accommodative changes of the wavefront aberration, lens shape and ciliary muscle in the emmetropic eyes of young adults. Ji C. He1, J. Wang2, M. C. Wei1, J. C. Mao1. 1New England College of Optometry, Boston, MA;2Bascom Palmer Eye Institute, Miami, FL 6010—B0159 Measurement of Accommodation with High Dynamic Range Using a Shack-Hartmann Wavefront Sensor and Dual Channel Accommodation Stimulus. Victor M. Hernandez1, 2, M. Ruggeri1, F. Manns1, 2, J. A. Parel1, 3.1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Miami, FL; 2Department of Biomedical Engineering, University of Miami, Biomedical Optics and Lasers Laboratory, Coral Gables, FL; 3Vision Cooperative Research Centre, Sydney, NSW, Australia 6043—B0222 A 19-Year Experience of Regional Anesthesia for the Surgical Repair of Open Globe Injuries. Andrew J. McClellan, J. J. Daubert, H. W. Flynn, S. Gayer. Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 6049—B0228 Clinicopathologic Characteristics and Outcomes of Lacerating Injuries to the Eye and Ocular Adnexa at a Tertiary Referral Center. Nathan W. Blessing1, B. P. Erickson1, A. M. Franco2, A. C. Ko1, S. Read1, W. W. Lee1.1Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2Miller School of Medicine, University of Miami, Miami, FL 6068—C0003 Quantitative analysis of microvascular network of the lid wiper area in contact lens wearers. Jianhua Wang1, H. Jiang1, X. Mao2, 1, W. Yan2. 1Ophthalmology, Bascom Palmer Eye Inst Lib, Miami, FL; 2Ophthalmology and Optometry, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China 6168—C0192 The Molecular Mechanisms Of Sterile Inflammation In Ischemic Retina. Dmitry V. Ivanov1, 2, I. Perea-Martinez1, D. Danek1, J. R. Naik1, S. Pappas1, X. Dvoriantchikova1, G. Dvoriantchikova1. 1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL; 2Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 6185—C0209 Wide-field imaging of birdshot chorioretinopathy. Francesco Pichi1, 3, C. Y. Lowder3, J. L. Davis2, H. Patel2, S. J. Haug4, E. Cunningham4, 5, S. K. Srivastava3. 1San Giuseppe Hospital, University Eye Clinic, Bologna, Italy; 2Bascom Palmer Eye Institute, Miami, FL; 3Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH; 4West Coast Medical Retina, San Francisco, CA; 5Department of Ophthalmogy, Standford University, San Francisco, CA
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