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innovation for biotech
Automated and Sterile Sampling from Bioreactors with bioPROBE
bioPROBE
The Key-Element for
PAT-Connectivity
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All day sampling – 24/7
Sterile and automated
No contamination risk
Minimal sample volume
Dead-volume free
Free sample timing
Patented sampling technology
 Disposable or steel sampling probe
 Installation in 12 mm ports
(adapter available)
 For all bioreactor types
 For all kinds of analytics
 Configuration via web-browser
 User-friendly interface
bioPROBE single
 Sterile & automated sampling for one cultivation
vessel
 Overnight & more - secure process control for any
specified period
bioPROBE quad
 Parallel sampling in four cultivation vessels
 Sterile separation of each cultivation system
without cross-contamination:
One bioreactor – One sampling probe set
bbi-biotech GmbH
www.bbi-biotech.com
innovation for biotech
bioPROBE System & SAM Series
bioPROBE
Sterile & Automated Sampling System
 single 22 x 50 x 25 cm
Size (W x D x H)
 quad 34 x 45 x 14 cm
Technical Details
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coolSAM
Cooled Storage for up to 8 Samples
Size (W x H x D)
 23 x 32 x 32 cm
Variants
 4 sample vessels à 50 ml
 8 sample vessels à 15 ml
Tempering
 -10 …+110 °C ± 1 °C
 +20 …+40 °C ± 0,5 °C
 Exact tempering and heating profile control
Additional Properties
 Complete automated control via bioPROBE
 Sample vessels 15 ml and 50 ml available with septa for sterile storage
 Additional sample vessels and sizes on request
orbitSAM
Serial Storage for up to 36 Samples
Size (W x H x D)
 22 x 50 x 25 cm
Variants
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Additional Properties
 Complete automated control via bioPROBE
 Sample vessels with septa for sterile storage available
 Optional: Cover box with UV-sterilized environment
autoSAM (Q1/2015)
Cooled Storage for up to 96 Samples
Size (W x H x D)
 62,5 x 32,5 x 45 cm
Variants
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Tempering
 +4 °C … +35 °C ± 1 °C
Additional Properties
 Complete automated control via bioPROBE
 Sample vessels with septa for sterile storage available
 Additional sample vessels and sizes on request
Sample volume: 5 - 50 ml ± 10 % (2 ml upcoming)
Maximal working pressure: up to 1 bar
Sample interval: up to 5 min
Sample count: up to 5000 sterile samplings in series
Media connections: Sample hoses at case front and sides, media
connections (sterile air, flushing) at case backside
 Sampling trigger possible via digital input from elsewhere
 Sampling log for documentation and quality management
 Configuration via browser with any OS
51 sample vessels à 15 ml
36 sample vessels à 20 ml or 30 ml
24 sample vessels à 50 ml,
Additional sample vessels and sizes on request
Up to four Thermo-Blocks in MTP-format
24 – 96 sample vessels à 2 ml
8 – 32 sample vessels à 15 ml
6 – 24 sample vessels à 50 ml
bbi-biotech GmbH
Koepenicker Straße 325, H 12
D-12555 Berlin
www.bbi-biotech.com
T: +49 (0) 30 65 76 39 40
F: +49 (0) 30 65 76 39 49
M: [email protected]