Electronic Brachytherapy Basal Cell Y Squamous Cell Y Keloids Y Melanoma N Externally Accessible Cavities Y Procedure Time 6 minutes1 per lesion, per fraction Setup Time ~ 15 minutes Particle Type/Treatment Delivery Mode Photons Modality Therapy Mode/Billing Coding Electronic Brachytherapy Penetration Depth 0-5 mm Pain Involved N Anesthesia Required N Post-Procedural Treatment N Practice Setup/Cost of Entry/Equipment cost Low Shielding Minimal Shielding Required (rolling shield) Mobile Y - (21”x31” footprint) Ongoing Consumable Costs? Y (Source Usage Contracts based on volume) Recurrence Rates 0% to date1 Radiation Therapy Coding CPT0182T Brachytherapy Coding Clinical Data Bhatnagar A. Electronic Brachytherapy for the Treatment of Nonmelanoma Skin Cancer: Results at 3 Years. Int J Radiat Oncol Biol Phys 2013;87:S65. Transform the Treatment of Non-Melanoma Skin Cancer Scalp Forehead Eyes Ears Nose Cheeks 1. Bhatnagar A. Electronic Brachytherapy for the Treatment of Nonmelanoma Skin Cancer: Results at 3 Years. Int J Radiat Oncol Biol Phys 2013;87:S65. 2. Bhatnagar A. Electronic Brachytherapy for the Treatment of Nonmelanoma Skin Cancer: Results at 3 Years. Int J Radiat Oncol Biol Phys 2013;87:S65. Scan barcode to go to website To learn more about Xoft®, visit us here: 101 Nicholson Lane, San Jose, CA 95134 • 408.493.1500 • 877.963.8327 • Fax 866.222.3404 • www.xoftinc.com ©2013 Xoft®, a subsidiary of iCAD. All rights reserved. Axxent and eBx are registered trademarks of Xoft® MC425 Rev A Xoft® Electronic Brachytherapy (eBx®) The Lat est Bre akth roug h in Radia tion Therapy Ajay Bhatnagar, MD “The Xoft System has helped expand our patient population. We currently treat skin cancer patients that we typically or historically were not able to treat with other modalities.” Elevate your cancer treatment program with Skin Electronic Brachytherapy (eBx®) by Xoft®. Ken B. - Skin eBx Patient Transform the treatment of NMSC By offering Electronic Brachytherapy (eBx) utilizing the Xoft System, radiation oncologists are able to partner with local dermatologists to treat non-melanoma skin cancer (NMSC) patients. The Xoft System utilizes an isotope-free miniaturized 50kV x-ray source to deliver targeted radiotherapy directly to the lesion. The low energy source offers fast dose fall-off, minimizing radiation exposure to normal healthy tissue. The treatment is non-invasive and painless. Unlike traditional radiation therapy options, Xoft eBx typically requires a total of eight fractions per lesion administered twice weekly for approximately six minutes per lesion. Skin eBx is particularly beneficial to patients who may find it difficult to comply with the three to four weeks of daily visits required by other radiation treatment options. Attract and retain your patients Grow your practice » Painless, non-invasive treatment option » » Ideal for challenging anatomical locations (face, scalp, lower legs, ears, elbows) » Treatment in a standard exam room (minimal shielding requirements) Targeted treatment results in excellent (93%) cosmesis » Increase patient volume » Mobility allows system to be used in multiple locations/centers » » » Treatment option for those not ideal for surgical excision e.g. comorbidities, blood thinning medications After Before 68-year-old woman with eye squamous cell carcinoma below Same 68-year-old left eye treated with 10 mm woman with squamous surface applicator using 40 Gy to cell carcinoma 20 a 3 mm depth. months post-treatment. 72 year old man with squamous cell ear carcinoma on right antihelix. Treated Same 72 year old man with 40 Gy to a 3 mm depth. with squamous cell carcinoma 1 year post » Fewer visits for improved patient convenience Partner with local dermatologists to expand your patient population “The after effects are minimal, if any. Cosmetically, I don’t think anybody could find the spot where I had the treatment.” treatment. 73-year-old woman with basal cell nose carcinoma on left tip of nose treated Same 73-year-old with 20 mm surface applicator using woman with basal cell 40 Gy to a 3 mm depth. carcinoma 1.5 years post treatment. Innovative technology positions your practice as a leader in the community Very tight skin on the lower leg would preclude easy surgical closure Clinical Results “Electronic Brachytherapy for the Treatment of Nonmelanoma Skin Cancer: Results at 3 Years2” 187 subjects, 275 lesions • • • Excellent (93%) cosmesis up to three years post-treatment Low toxicity No Recurrences leg possibly resulting in delayed healing and would interfere with ambulation: Same patient, 3 months 20 mm surface applicator using 40 Gy. post-treatment. Cost Effective Radiation Treatment Option “Treatment of non-melanoma skin cancer with HDR electronic brachytherapy using surface applicators was effective” and “a convenient non-surgical treatment option for non-melanoma skin cancer patients.” NMSC lesions were treated with Electronic High Dose Rate Brachytherapy using surface applicator to a dose of 40 Gy in eight fractions, delivered twice weekly with minimum of 48 hour interval. A 10-50 mm surface applicator was selected to allow for complete coverage of target lesion with acceptable margin1. Xoft 50kV x-ray source Treat in office settings Skin Applicators (10, 20, 35 or 50 mm in diameter) Eye, nose, ear images courtesy of Ajay Bhatnagar, MD, MBA, Cancer Treatment Services Arizona, Affiliate of 21st Century Oncology, DermeBx. Leg images courtesy of Ken Gross, M.D., Skin Surgery Medical Group, Inc.