1. health and fitness
2. addiction

Baker, Nathaniel L CURICULUM VITAE Name: Nathaniel L Baker Office Address: 135 Cannon Street Suite 303 Charleston, SC 29425 Office Phone: 843‐792‐5028 Office Email: [email protected] Citizenship and/or Visa Information: USA Education: Institution Years Degree/Date Field of Study Georgia Regents University (Former Augusta State U) 1999‐2005 B.S. 2005 Mathematics Georgia Regents University (Former Medical Col of GA) 2006‐2008 M.S. 2008 Biostatistics GPA: 3.75/4.00 Thesis: A Regression Based Transmission/Disequilibrium Test for Quantitative Traits using Sib‐Pair Family Data; Under the Tutelage of Varghese George PhD. Faculty Appointments: Years Rank Institution Department 2013‐ Research Instructor MUSC Dept of Public Health Sciences 2012‐2013 Research Instructor MUSC Dept of Medicine; Division of Biostatistics and Epidemiology 2009‐2012 Research Associate MUSC Dept of Medicine; Division of Biostatistics and Epidemiology 2008‐2009 Research Associate MUSC Dept of Biostatistics, Bioinformatics and Epidemiology Administrative Appointments: Years Position Institution Department None Other Experience: Years Position Institution Department 2006‐2008 Grad Res Assistant GRU/MCG Biostatistics 2005‐2006 Mathematics Inst. Heph HS Mathematics 2005 Lab Assistant ASU Chemistry and Physics 2002‐2005 Lab Assistant ASU Mathematics and Computer Sci. Membership in Professional organizations Current Past 2006‐2010 American Statistical Association 2006‐2013 Southeast SAS Users Group SC Chapter 2004‐2005 ASU Physics Society 2003‐2005 Mathematical Association of America 2000‐2005 ASU Euclidean Society Positions Held: President (2004‐2005) -1Last Updated 6/25/2015
Baker, Nathaniel L Editorial Positions: 2011‐2013 Review Editor: Frontiers in Applied Genetic Epidemiology (Frontiers) 2012‐2015 Ad Hoc Reviewer: Journal of Child and Adolescent Substance Abuse Major Teaching Responsibilities: None Major Clinical Interests and Responsibilities: None University/Departmental Committee Membership 2008‐Present Dept of Public Health Sciences Social Committee (Chair 2011‐2014) 2013 Dept of Public Health Sciences IYOS Committee DSMB Membership 2011‐Present: COPE Study (HR # 20279), PI Sudie Back, Department of Psychiatry 2012‐2015: SNUS Study (R01CA154992‐02), PI Matthew Carpenter, Department of Psychiatry 2104‐Present: TIP TOP Study (R01), PI Matthew Carpenter, Department of Psychiatry Lectures and Presentations: Contributed Talks, Lectures, and Posters co‐authored by Nathaniel L Baker 2008‐2009 1.
Kevin M. Gray, Nathaniel L. Baker, Matthew J. Carpenter, Himanshu P. Upadhyaya. Attention‐
deficit/hyperactivity disorder (ADHD) and nicotine withdrawal in adolescent smokers. (Poster) Presented at the Society for Nicotine and Tobacco Research Meeting, Dublin, Ireland, January, 2009. 2.
Maria F Lopes‐Virella, Richard L Klein, Rickey E Carter, Alicia J Jenkins, Timothy J Lyons, Nathaniel L Baker, DCCT/EDIC Research Group, Gabriel Virella. LDL‐Containing Immune Complexes in the DCCT/EDIC Cohort: Associations with Lipoprotein Subclasses. (Oral Presentation) Presented at the American Diabetic Association 69th Scientific Session, New Orleans, LA, June, 2009 3.
Matthew J. Carpenter, Nathaniel L. Baker, Kevin M. Gray, Alvin L. Lewis, Erin Klintworth, Ashley Leinbach, Himanshu P. Upadhyaya. Assessment of Nicotine Dependence among Adolescent Smokers: A Comparison of Measures. (Poster) Presented at the College on Problems of Drug Dependence, Reno NV, June, 2009 4.
Alvin L. Lewis, Kevin M. Gray, Matthew J. Carpenter, Nathaniel L. Baker, Erin M. Klintworth, Ashley S. Leinbach, Himanshu P. Upadhyaya. Attention‐Deficit/Hyperactivity Disorder (ADHD) and Nicotine Withdrawal Symptoms among Treatment‐Seeking Adolescent Smokers. (Poster) Presented at the College on Problems of Drug Dependence, Reno NV, June, 2009 5.
Kevin M. Gray, Matthew J. Carpenter, Nathaniel L. Baker, Erin M. Klintworth, Ashley S. Leinbach, Himanshu P. Upadhyaya. Bupropion SR and Contingency Management in Adolescent Smokers: Main Findings. (Oral Presentation) Presented at the College on Problems of Drug Dependence, Reno NV, June, 2009 -2Last Updated 6/25/2015
Baker, Nathaniel L 6.
Megan Moran‐Santa Maria, Matthew W Feltenstein, Aimee L McRae, Sudie E Back, Nathaniel L Baker, Kimber L Price, Lisa M Jenkins, Kathleen T Brady. Ovarian Hormones and Subjective Responding to Stress and Cues in Cocaine Dependent Females. (Poster) Presented at the College on Problems of Drug Dependence, Reno NV, June, 2009 Karen Hartwell, Sudie E Back, Stacia M DeSantis, Mike E Saladin, Aimee L McRae‐Clark, Kimber L Price, Nathaniel L Baker, Eve G Spratt, Mary J Kreek, Kathleen T Brady. Reactivity to laboratory stress provocation predicts relapse to cocaine. (Poster) Presented at the College on Problems of Drug Dependence, Reno NV, June, 2009 7.
2009‐2010 8.
Nathaniel L Baker, Rickey E Carter. Biomarker Relationships with Nephropathy outcomes in Type I Diabetes patients in the EDIC study. (Oral Presentation) Presented to the MUSC EDIC study group. Charleston, SC, July, 2009 9.
Nathaniel L Baker Jittering: A SAS® Macro to Shift Overlapping Plots. (Oral Presentation) Presented at the South East SAS Users Group, Birmingham, AL, October, 2009. 10.
Lee Lewis IV, Kevin M. Gray, Nathaniel L. Baker, Matthew J. Carpenter, Himanshu P. Upadhyaya. Getting Off on a Good Foot: Does Abstinence on a Pre‐Determined Quit Date Guarantee Anything in Adolescent Smokers? (Poster) Presented at AACAP, Honolulu, HI, October, 2009 11.
Kevin M. Gray, Nathaniel L. Baker, Matthew J. Carpenter, A. Lee Lewis IV, Himanshu P. Upadhyaya. A Randomized, Double‐Blinded, Placebo‐Controlled Trial of Bupropion SR, with and without Contingency Management, for Smoking Cessation in Adolescents. (Poster) Presented at AACAP, Honolulu, HI, October, 2009 12.
Himanshu P. Upadhyaya, Kevin M. Gray, Matthew J. Carpenter, Nathaniel L. Baker. Bupropion and Contingency Management for Nicotine Dependence. (Oral Presentation) Presented at AACAP, Honolulu, HI, October, 2009 13.
Maria F Lopes‐Virella, Rickey E Carter, Nathaniel L Baker, The DCCT/EDIC Research Group, Gabriel T. Virella. High Levels of Oxidized Low Density Lipoprotein‐Immune Complexes Are Associated With Increased Odds to Develop Nephropathy in Type I Diabetes. (Poster) Presented at the American Heart Association Scientific Session, Orlando Fl, November, 2009 14.
Maria F Lopes‐Virella, Kelly J Hunt, Nathaniel L Baker, John Lachin, Gabe Virella. Oxidized LDL and AGE‐ LDL immune complexes strongly predict the development of Cardiovascular Disease in Type 1 Diabetes. (Oral Presentation) Presented at 70th American Diabetes Association Scientific Session, Orlando, Fl, June, 2010. 15.
Bryan K Tolliver, Kimber L Price, Nathaniel L Baker, Steve D LaRowe, Annie N Simpson, Aimee L McRae‐
Clark, Michael E Saladin, Stacia M DeSantis, Elizabeth Chapman, Margaret Garrett, Kathleen T Brady. Pronounced attentional Bias in methamphetamine dependent Subjects upon methamphetamine cue. (Poster) Presented at College on Problems of Drug Dependence, Scottsdale, Az, June, 2010 -3Last Updated 6/25/2015
Baker, Nathaniel L 16.
Aimee L McRae‐Clark, Rickey E Carter, Kimber L Price, Nathaniel L Baker, Michael E Saladin, Kathleen T Brady. Stress and Cue‐Elicited Craving in Marijuana‐Dependent Individuals. (Poster). Presented at College on Problems of Drug Dependence, Scottsdale, Az, June, 2010 2010‐2011 17. Kimber L Price, Stacia M DeSantis, Annie N Simpson, Bryan K Tolliver, Aimee L McRae‐Clark, Michael E Saladin, Nathaniel L Baker, Mark T Wagner, Elizabeth Chapman, Margaret Garrett, Kathleen T Brady. Cognitive Performance in Methamphetamine‐Dependent Individuals from Rural South Carolina: Potential Impact of Demographic Variables. (Poster). Presented at TRMA, Pray, Mt, July, 2010 18. Bryan K Tolliver, Kimber L Price, Nathaniel L Baker, Steve D LaRowe, Annie N Simpson, Aimee L McRae‐
Clark, Michael E Saladin, Stacia M DeSantis, Elizabeth Chapman, Margaret Garrett, Kathleen T Brady. Attentional Bias for Methamphetamine Related Cues in Subjects with Methamphetamine Dependence: Relationship to Drug Use History. (Poster). Presented at TRMA, Pray, Mt, July, 2010 19. Jennifer A Dixon, Amy M Goodman, William F Gaillard III, William T Rivers, Richard A McKinney, Rupak Mukherjee, Nathaniel L Baker, John S Ikonomidis, Francis G Spinale. Hemodynamics and Myocardial Blood Flow Patterns Following Placement of a Cardiac Passive Restraint Device in a Model of Dilated Cardiomyopathy. (Poster) Presented at the American Heart Association Scientific Session, Chicago, IL, November, 2010 20. Jennifer A Dixon, Robert C Gorman, Robert E Stroud, Evan C Meyer, Elizabeth C O’Quinn, Nathaniel L Baker, Masato Morita, Hirotsugu Hamamoto, Liam P Ryan, Joseph H Gorman III, Francis G Spinale. Targeted Regional Injection of Biocomposite Microspheres Alter Post Myocardial Infarction remodeling. (Poster) American Heart Association Scientific Session, Chicago, IL, November, 2010 21. Eric M Graham, Andrew M Atz, Ryan J Butts, Nathaniel L Baker, Sinai C Zyblewski, Rachael L Deardorff, Scott T Reeves, Scott M Bradely, Francis G Spinale. Standardized Preoperative Corticosteroid Treatment in Neonates Undergoing Cardiac Surgery‐ Results from a Randomized Trial. (Oral Presentation) Presented at the American Heart Association Scientific Session, Chicago, IL, November, 2010 22. Eric M Graham, Andrew M Atz, Ryan J Butts, Nathaniel L Baker, Robert E Stroud, Rachael L Deardorff, Scott T Reeves, Scott M Bradely, Francis G Spinale. Preoperative Steroid Treatment Does Not Improve Markers of Inflammation or Outcomes Following Cardiac Surgery in Neonates. (Poster) Presented at the American Heart Association Scientific Session, Chicago, IL, November, 2010 23. Eric M Graham, Andrew M Atz, Ryan J Butts, Nathaniel L Baker, Sinai C Zyblewski, Rachael L Deardorff, Stacia M DeSantis, Scott T Reeves, Scott M Bradely, Francis G Spinale. Standardized Preoperative Corticosteroid Treatment in Neonates Undergoing Cardiac Surgery‐ Results From a Randomized Trial. (Poster) Presented at the Pediatric Cardiac Intensive Care Society Meeting, Miami, FL, December, 2010 24. Nathaniel L Baker. Estimating Stratified two Factor Interactions in a 3 Factor Design in SAS Proc Mixed. (Oral Presentation) Presented to the DBE Collaborative Unit, Medical University of South Carolina, Charleston, SC, January, 2011. -4Last Updated 6/25/2015
Baker, Nathaniel L 25. Nathaniel L Baker. An Introduction to Graphics in SAS. (Oral Presentation) Presented as a Guest Lecturer Biometry 789‐02, Computing for Research, DBE, Medical University of South Carolina, January, 2011 Eric M Graham, Andrew M Atz, Ryan J Butts, Nathaniel L Baker, Sinai C Zyblewski, Rachael L Deardorff, Stacia M DeSantis, Scott T Reeves, Scott M Bradely, Francis G Spinale. Standardized preoperative corticosteroid treatment in neonates undergoing cardiac surgery – Results from a randomized trial. Presented at the 15th Annual Update on Pediatric Cardiovascular Disease. Scottsdale AZ, Feb. 2011. Recipient of the 8th Annual Outstanding Investigator Award. 26. 27. Nathaniel L Baker. Analysis of Coronary Artery Calcification Data: Modeling Considerations. Presented at Tea Time for Science, DBE, Medical University of South Carolina, April, 2011 28. Kimber L Price, Nathaniel L Baker, Katherine S Nicholas, Kathryn S Allenby, Cullen B McWhite, K Stephen Fischer, Kathleen T Brady. Effect of stress on attentional bias and cognition in marijuana dependent individuals. (Poster) Presented at CPDD, Hollywood, FL, June, 2011 29. Kevin M. Gray, Matthew J. Carpenter, Stacia M DeSantis, Nathaniel L. Baker. A randomized controlled trial of N‐Acetylcysteine in cannabis dependent adolescents: main findings. (Poster) Presented at CPDD, Hollywood, FL, June, 2011 30. Nathaniel L Baker, Maria F Lopes‐Virella, Kelly J Hunt, Gabriel Virella. Oxidized LDL immune complex and the progression of retinopathy in Type 1 diabetes. (Oral Presentation) Presented at the 71st American Diabetes Association Scientific Session, San Diego, CA, June, 2011. 2011‐2012 31. Aaron M Schott, Amanda M Wagner, Erin N Lindley, Nathaniel L Baker, Aimee McRae‐Clark. Effect of intranasal Oxytocin on marijuana craving. (Poster) Presented at the MUSC SGS Student Research Day, Charleston SC, November, 2011. 32. Amanda T Roten, Nathaniel L Baker, Kevin M Gray. Marijuana Craving Trajectories During an Adolescent Marijuana Cessation Pharmacotherapy Study. (Poster) Presented at the South Carolina Psychiatric Association 2012 Meeting, Charleston SC, January, 2012. Received 1st place in resident poster competition. 33. Kevin M Gray, Nathaniel L Baker, Amanda T Roten, Matthew J Carpenter. What happens to cigarette smoking behavior when adolescents participate in a marijuana cessation pharmacotherapy trial? (Poster) Presented at the 18th Society for Research on Nicotine and Tobacco, Houston TC, March 2012. 34. Kelly J Hunt, Nathaniel L Baker, Patricia Cleary, Jye‐Yu Backlund, Gabriel Virella, Maria F Lopes‐Virella,. Oxidized LDL and AGE‐ LDL in circulating immune complexes strongly predict development and progression of Carotid IMT in Type 1 Diabetes. (Oral Presentation) Presented at the Epidemiology and Prevention | Nutrition, Physical Activity and Metabolism 2012 Scientific Sessions, San Diego CA, March 2012. -5Last Updated 6/25/2015
Baker, Nathaniel L 35. 36. 37. 38. Abid Irshad, Rebecca Leddy, Madeline Lewis, Nathaniel L Baker, Susan Ackerman, Amy Campbell, Abbie Cluver, Laura Isley. Significance of various ultrasound features of the breast cancers for predicting various prognostic factors: Thinking beyond the BI‐RADS. (Oral Presentation) American Roentgen Ray Society Annual Meeting, Vancouver BC, April 2012. Maria F Lopes‐Virella, the VADT Group of Investigators, Gabriel Virella, Kelly J Hunt, Nathaniel L Baker, and Thomas Moritz. The Levels of MDA‐LDL in Circulating Immune Complex Predict Mycocardial Infarction in the VADT Study. (Poster) Arteriosclerosis, Thrombosis and Vascular Biology 2012 Scientific Sessions, Chicago IL, April 2012. Nathaniel L Baker, Kelly J Hunt, Tim Lyons, Rick Klein, Patricia A Cleary, Gabe Virella, Maria F Lopes‐
Virella, and the DCCT group of investigators. Markers of inflammation are associated with development of abnormal albuminuria in Type 1 Diabetics. (Oral Presentation) American Diabetes Association 72nd Scientific Session, Philadelphia PA, June 2012 Aimee L McRae‐Clark, Megan Moran‐Santa Maria, Nathaniel L Baker, Kathleen T Brady. Effect of Oxytocin on Stress‐Induced Reactivity in Marijuana Dependent Individuals. (Oral Presentation) College on Problems of Drug Dependence, Palm Springs, CA, June 2012. 2012‐2013 39. Maria F Lopes‐Virella, Nathaniel L Baker, Kelly J Hunt, Rick Klein, Patricia A Cleary, Gabe Virella, and the DCCT group of investigators. The role of inflammation on Coronary Artery Disease in Type 1 Diabetes. (Invited Presentation) American Diabetes Association 72nd Scientific Session, Philadelphia PA, June 2012 40. Kevin M. Gray, Matthew J. Carpenter, Nathaniel L. Baker, Stacia M DeSantis, Elizabeth Kryway, Karen J Hartwell, Aimee L McRae‐Clark, Kathleen T Brady. Neurobiologically‐Informed Treatment Development: A Randomized Controlled Trial of N‐Acetylcysteine In Marijuana‐Dependent Adolescents. (Symposium Presentation) American Association of child and Adolescent Psychiatry 59th Annual Meeting, San Francisco CA, October 2012. 41. Amanda T Roten, Nathaniel L. Baker, Kevin M. Gray. Marijuana Craving Trajectories During and Adolescent Marijuana Cessation Pharmacotherapy Study. (Poster) American Association of child and Adolescent Psychiatry 59th Annual Meeting, San Francisco CA, October 2012. 42. Karen J Hartwell, Owens M, Nathaniel L Baker, Moran‐Santa Ana M, Brady KT, McRae‐Clark AL. Impulsivity in cocaine dependent cigarette smokers and non‐smokers: Does cigarette smoking make a difference? (Poster) 23rd Annual Meeting of the American Academy of Addiction Psychiatry, Miami, FL, December, 2012. 43. Kapral TB, Hartwell KJ, Baker NL, Shaftman SR, Killeen T, McRae‐Clark AL. Differences in motivations to smoke marijuana between treatment and non‐treatment seeking marijuana‐dependent individuals. (Poster) 23rd Annual Meeting of the American Academy of Addiction Psychiatry, Miami, FL, December, 2012. 44. Nathaniel L Baker. Statistical Graphics for the SAS System. (Oral Presentation) Presented as a Guest Lecturer Biometry 789‐02, Computing for Research, DBE, Medical University of South Carolina, January, 2013 -6Last Updated 6/25/2015
Baker, Nathaniel L 45. 46. 47. 48. 49. 50. 51. Robert C. Glenn, Erin Seery, Dennis Orwat, Tamas Szabo, Nathaniel Baker,Christopher Pelic, Paul Everman, Robert Malcolm, Mark Hamner. Subanesthetic Ketamine in Depressed Veterans with a History of Alcohol Dependence. (Poster) SCPA, Charleston, SC, February, 2013. Erin Seery, Robert C. Glenn, Dennis Orwat, Tamas Szabo, Christopher Pelic, Paul Everman, Nathaniel L Baker, Robert Malcolm, Mark Hamner. Ketamine’s Impact on Cravings for Alcohol in a Population of Veterans with Depression and Alcohol Dependence. (Poster) SCPA, Charleston, SC, February, 2013. Michael E Saladin, Kevin M Gray, Matthew J Carpenter, Nathaniel L Baker, Steven D LaRowe, Karen J Hartwell, Erin A McClure, and Himanshu P Upadhyaya. Menstrual Cycle and Gender Differences in Craving and Stress Reactivity to Stress Cues. (Poster) 19th Annual Meeting of the Society for Research on Nicotine and Tobacco, Boston, MA, March, 2013. Kevin M. Gray, Michael E. Saladin, Nathaniel L. Baker, Erin A. McClure, Matthew J. Carpenter, Karen J. Hartwell. Varenicline versus Nicotine patch for smoking cessation in women: Efficacy findings from a four week double blind trial. (Poster) 19th Annual Meeting of the Society for Research on Nicotine and Tobacco, Boston, MA, March, 2013. Kelly J Hunt, Nathaniel L Baker, Richard L Klein, Patricia A Cleary, Gabe Virella, Maria F Lopes‐Virella and the DCCT/EDIC group of Investigators. Novel biomarkers appear consequence rather than cause of atherosclerosis in type 1 diabetics. (Poster) 73rd Scientific Session of the American Diabetes Associations, Chicago, IL, June, 2013. Nathaniel L Baker, Kelly J Hunt, Richard L Klein, Samar M Hammad, Mohammed M. Al Gabdan, Gabe Virella, Maria F Lopes‐Virella, and the DCCT/EDIC group of Investigators. Plasma levels of very long chain ceramide species are associated with decreased odds of macroalbuminuria. (Poster) 73rd Scientific Session of the American Diabetes Associations, Chicago, IL, June, 2013. Michael E Saladin, Kevin M Gray, Tara Abbot, Steve LaRowe, Aimee McRae‐Clark, Stacia DeSantis, Nathaniel L Baker, Sudie Back, Karen Hartwell, Kathleen T Brady. Post Retrieal Propranolol may Alter Reconsolidation of Trauma Memory in individuals with PTSD and Comorbid Alcohol Dependence. (Poster) 75th Annual Meeting of the College of Problems on Drug Dependence, San Diego, CA, June 2013. 2013‐2014 52. Megan M Moran‐Santa Maria, Aimee L McRae‐Clark, Nathan L Baker, and Kathleen T Brady. Gender Differences in Subjective Responses to Yohimbine Administration Between Cocaine‐Dependent Men and Women. The 10th Annual NIH Interdisciplinary Women’s Health Research Symposium, Bethesda, MD, October 2013. 53. Kevin M Gray, Michael E Saladin, Nathaniel L Baker, Erin A McClure, Karen J Hartwell, and Matthew J Carpenter. Varenicline Versus Nicotine Patch for Smoking Cessation in Women: Efficacy Findings from a four‐week Double Blind Trial. The 10th Annual NIH Interdisciplinary Women’s Health Research Symposium, Bethesda, MD, October 2013 54. Karen J Hartwell, Nathaniel L Baker, Aimee L McRae‐Clark. Sex Differences in Motivations to use in Cannabis Dependent Adults. (Poster) 24th Annual Meeting of the American Academy of Addiction Psychiatry, Scottsdale, AZ, December 2013. -7Last Updated 6/25/2015
Baker, Nathaniel L 55. 56. 57. 58. 59. Megan Moran‐Santa Maria, Aimee McRae‐Clark, Nathaniel L Baker, Viswanathan Ramakrishnan, Kathleen T Brady. Response to yohimbine and cocaine cues in cocaine dependent individuals. (Poster) American College of Neuropsychopharmacolgy (ACNP) 52nd Annual Meeting, Hollywood, FL, December 2013. Michael E Saladin, Kevin M Gray, Matthew J Carpenter, Nathaniel L Baker, Erin A McClure. Increasing Progesterone Levels in Free Cycling Women Smokers Are Associated with Abstinence During a Medication Assisted Quit Attempt. (Poster) 20th Annual Meeting of the Society for Research on Nicotine and Tobacco, Seattle, WA, February, 2014. Nathaniel L Baker. Statistical Graphics for the SAS System. (Oral Presentation) Presented as a Guest Lecturer Biometry 789‐02, Computing for Research, DBE, Medical University of South Carolina, January, 2014 Nathaniel L Baker, Paul J Nietert. A Picture is Worth a Thousand Words: Graphical Display of Data and Statistical Analysis for Clinical Research. (Invited Oral Presentation) Presented for the MUSC Apple Tree Society, Medical University of South Carolina, April, 2014 Nathaniel L Baker, Courtney McCracken. Statistical Consulting in Medical Research. Presented as a Guest Lecturer STAT 8870, Biostatistical Consulting in Research, Department of Biostatistics and Epidemiology, Georgia Regents University, June 2014 2014‐2015 60. Amanda T Roten, Nathaniel L Baker, Kevin M Gray. Cognitive outcomes with abstinence in a placebo‐
controlled pharmacotherapy trial for youth with Marijuana dependence. (Poster) 61st Annual Meeting of the American Academy of Child and Adolescent Psychiatry, San Diego, California, October, 2014 61. Julianne C Flanagan, Megan Moran Santa‐Maria, Nathaniel L Baker, Aimee L McRae‐Clark., Kathleen T Brady. Examining the Influence of Adverse Childhood Experiences on the Effects of Oxytocin on Stress Reactivity among Individuals with Cocaine Dependence. (Poster) the annual convention of the Association for Behavioral and Cognitive Therapies, Philadelphia, Pennsylvania, November, 2014. 62. Samar Hammad, Richard Klein, Nathaniel L Baker, Maria F Lopes‐Virella, Kelly J Hunt, Gabriel Virella, DCCT/EDIC Research Group. Increased Plasma Levels of Select Deoxy‐Ceramide and Ceramide Species are Associated with Increased Odds of Diabetic Neuropathy in Type 1 Diabetes. (Oral Presentation) 2015 International Ceramide Conference/Sphingolipid Club Joint Meeting, Izmir, Turkey, May, 2015. 63. Nathaniel L Baker, Maria F Lopes‐Virella, Kelly J Hunt, Patricia A Cleary, Richard Klein, Gabriel Virella, DCCT/EDIC Research Group. Change in biomarkers of inflammation according to development and progression of albuminuria. (Poster) 75th Scientific Session of the American Diabetes Associations, Boston, MA June, 2015. 64. Kelly J Hunt, Maria F Lopes‐Virella, Nathaniel L Baker, John Arthur, Gabriel Virella, VADT Research Group. Modified LDL in circulating immune complexes predict macro‐albuminuria in the VADT study. (Poster) 75th Scientific Session of the American Diabetes Associations, Boston, MA June, 2015. -8Last Updated 6/25/2015
Baker, Nathaniel L Publications: Peer Reviewed Journal Articles Published/Accepted: 1.
Abid Irshad, Susan J. Ackerman, Munazza Anis, Amy S. Campbell, Atif Hashmi, Nathaniel L. Baker. Can the smallest depth of ascitic fluid on sonograms predict the amount of drainable fluid? Journal of Clinical Ultrasound. 2009 October; 37 (8): 440‐444. 2.
Sudie E Back, Karen Hartwell, Stacia M DeSantis, Michael E Saladin, Aimee L McRae‐Clark, Kimber L Price, Megan M Moran‐Santa Maria, Nathaniel L Baker, Eve Spratt, Mary Jeanne Kreek, Kathleen T Brady. Reactivity to Laboratory Stress Provocation Predicts Relapse to Cocaine. Drug and Alcohol Dependence. 2010 January; 106 (1): 21‐27. 3.
Brian K. Tolliver, Aimee McRae‐Clark, Michael Saladin, Kimber L Price, Annie N Simpson, Stacia M Desantis, Nathaniel L Baker, Kathleen T Brady. Determinants of Cue‐Elicited Craving and Physiologic Reactivity in Methamphetamine‐Dependent Subjects in the Laboratory. The American Journal of Drug and Alcohol Abuse. 2010 March; 36 (2): 106‐113 4.
Kevin M Gray, Nathaniel L Baker, Matthew J Carpenter, A. Lee Lewis, & Upadhyaya, H. P. Attention‐Deficit/Hyperactivity Disorder (ADHD) Confounds Nicotine Withdrawal Self‐Report in Adolescent Smokers. American Journal on Addictions. 2010 July; 19 (4): 325‐331 5. Kimber L Price, Michael E Saladin, Nathaniel L Baker, Bryan K Tolliver, Stacia M DeSantis, Aimee McRae‐
Clark, Kathleen T Brady. Extinction of Drug Cue Reactivity in Methamphetamine‐Dependent Individuals. Behaviour Research and Therapy. 2010 September; 48: 860‐865 6. Megan M Moran‐Santa Maria, Aimee L McRae‐Clark, Sudie E Back, Stacia M DeSantis, Nathaniel L Baker, Eve G Spratt, Annie N Simpson, Kathleen T Brady. Influence of Cocaine Dependence and Early Life Stress on Pituitary‐Adrenal Axis Responses to CRH and the Trier Social Stressor. Psychoneuroendocrinology. 2010 November; 35: 1492‐1500. 7. Matthew J Carpenter, Nathaniel L Baker, Kevin M Gray, Himanshu P Uapdhyaya. Assessment of Nicotine Dependence among Adolescent and Young Adult Smokers: A Comparison of Measures. Addictive Behaviors. 2010 November; 35: 977‐982 8. Kevin M Gray, Matthew J Carpenter, Nathaniel L Baker, Karen J Hartwell, A Lee Lewis, D. Walter Hiott, Deborah Deas, Himanshu P Upadhyaya. Bupropion SR and Contingency Management for Adolescent Smoking Cessation: A Randomized, Double Blind, Placebo‐Controlled Trial. Journal of Substance Abuse Treatment. 2011 January; 40: 77‐86. 9. Maria F Lopes‐Virella, Nathaniel L Baker, Kelly J Hunt, John Lachin, David M Nathan, Gabriel Virella, and the DCCT/EDIC Research Group. Oxidized LDL Immune Complexes and Coronary Artery Calcification in Type 1 Diabetes. Atherosclerosis. 2011 February; 214: 462‐467 10. Maria F Lopes‐Virella, Kelly J Hunt, Nathaniel L Baker, John Lachin, David M Nathan, Gabriel Virella, and the DCCT/EDIC Research Group. Oxidized LDL and AGE‐ LDL Immune Complexes Strongly Predict the Development of Vascular Disease in Type 1 Diabetes. Diabetes. 2011 February; 60: 582‐589. -9Last Updated 6/25/2015
Baker, Nathaniel L 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. Richard L Klein, Rickey E Carter, Alicia J Jenkins, Timothy J Lyons, Nathaniel L Baker, Gregory E Gilbert, Gabriel Virella, Maria F Lopes‐Virella and the DCCT/EDIC Research Group. LDL‐Containing Immune Complexes in the DCCT/EDIC Cohort: Associations with Lipoprotein Subclasses. Journal of Diabetes and its Complications. 2011 March; 25: 73‐82. Stacia M DeSantis, Nathaniel L Baker, Sudie E Back, Eve G Spratt, Jody D Ciolino, Megan M Moran‐
Santa Maria, Dipankar Bandyopadhya, Kathleen T Brady. Gender differences in the Effect of Early Life Trauma on HPA Axis Functioning. Depression and Anxiety. 2011 May; 28: 383‐392. Jennifer A Dixon, Robert C Gorman, Robert E Stroud, Rupak Mukherjee, Evan C Meyer, Nathaniel L Baker, Masoto Morita, Hirotsugu Hamamoto, Liam P Ryan, Joseph H Gorman, Francis G Spinale. Targeted Regional Injection of Biocomposite Microspheres Alters Post‐Myocardial Infarction Remodeling and Matrix Proteoytic Pathways. Circulation. 2011 September; 124:S35‐S45 Kimber L Price, Stacia M DeSantis, Annie N Simpson, Brian K Tolliver, Aimee McRae‐Clark, Michael E Saladin, Nathaniel L Baker, Mark Wagner, Kathleen T Brady. The Impact of Clinical and Demographic Variables on Cognitive Performance in Methamphetamine‐dependent Individuals in Rural South Carolina. American Journal on Addictions. 2011 September; 20; 447‐455. Aimee L McRae‐Clark, Rickey E Carter, Kimber L Price, Nathaniel L Baker, Suzanne Thomas, Kathleen Giarla, Katherine Nicholas, Kathleen T Brady. Stress and Cue‐Elicited Craving and Reactivity in Marijuana‐Dependent Individuals. Psychopharmacology. 2011 November; 218:49‐58. Jennifer A Dixon, Amy M Goodman, William F Gaillard, William T Rivers, Richard A McKinney, Rupak Mukherjee, Nathaniel L Baker, John S Ikonomidis, Francis G Spinale. Hemodynamics and Myocardial Blood Flow Patterns after Placement of a Cardiac Passive Restraint Device in a Model of Dilated Cardiomyopathy. The Journal of Thoracic and Cardiovascular Surgery. 2011 November; 142 (5): 1038‐
1045. Abid Irshad, Susan J Ackerman, Kenneth M Spicer, Nathaniel L Baker, Amy S Campbell, Anis Munazza, Mehwish Shazly. Ultrasound Evaluation of Gallbladder Dyskinesia: Comparison of Scintigraphy and Dynamic 3D and 4D Ultrasound Techniques. The American Journal of Roentgenology. 2011 November; 197 (5): 1103‐1110. Eric M Graham, Andrew M Atz, Ryan J Butts, Nathaniel L Baker, Sinai C Zyblewski, Rachael L Deardorff, Stacia M DeSantis, Scott T Reeves, Scott M Bradley, Francis G Spinale. Standardized Preoperative Corticosteroid Treatment in Neonates undergoing Cardiac Surgery‐Results from a Randomized Trial. The Journal of Thoracic and Cardiovascular Surgery. 2011 December; 142 (6): 1523‐
1529. Maria F Lopes‐Virella, Rickey E Carter, Nathaniel L Baker, Gabriel Virella, and the DCCT/EDIC Research Group High Levels of Oxidized LDL‐Immune Complexes Are Associated With Increased Odds To Develop Nephropathy In Type 1 Diabetes. Nephrology Dialysis Transplantation. 2012 April; 27(4): 1426‐1423. Bryan K Tolliver, Kimber L Price, Nathaniel L Baker, Steven D LaRowe, Annie N Simpson, Aimee L McRae‐
Clark, Michael E Saladin, Stacia M DeSantis, Kathleen T Brady. Impaired Cognitive Performance in - 10 Last Updated 6/25/2015
Baker, Nathaniel L Subjects with Methamphetamine Dependence During Exposure to Neutral Versus Methamphetamine‐
Related Cues. The American Journal of Drug and Alcohol Abuse. 2012 May; 38(3): 251‐259. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. Maria F Lopes‐Virella, Nathaniel L Baker, Kelly J Hunt, Timothy J Lyons, Alicia Jenkins, Gabriel Virella, and the DCCT/EDIC Research Group. High Concentrations of AGE‐LDL and Oxidized LDL in Circulating Immune Complexes are Associated with Progression of Retinopathy in Type 1 Diabetes. Diabetes Care. 2012 June; 35: 1333‐1340. Kevin M. Gray, Matthew J. Carpenter, Nathaniel L. Baker, Stacia M DeSantis, Elisabeth Kryway, Karen J Hartwell, Aimee L McRae‐Clark, Kathleen T Brady. A double‐blind randomized controlled trial of N‐
Acetylcysteine in cannabis dependent adolescents. American Journal of Psychiatry. 2012 August 169; 8: 805‐812. Maria F Lopes‐Virella, Kelly J Hunt, Nathaniel L Baker, Thomas Moritz, Gabriel Virella, and the VADT group of Investigators. The Levels of MDA – LDL in Circulating Immune Complexes predict Myocardial Infarction in the VADT study. Atherosclerosis. 2012 October; 224:526‐531. Gabriel Virella, Joan Colglazier, Charlyne Chassereau, Kelly Hunt, Nathaniel Baker, Maria Lopes‐Virella. Immunoassay of Modified Forms of Human Low Density Lipoprotein in Isolated Circulating Immune Complexes. Journal of Immunoassay and Immunochemistry. 2013 January; 34 (1):61‐74. Abid Irshad, Rebecca J Leddy, Etta D Pisano, Nathaniel L Baker, Madelene C Lewis, Susan J Ackerman, Amy S Campbell. Assessing the role of ultrasound in predicting the biological behavior of breast cancers. The American Journal of Roentgenology. 2013 February; 200: 284‐290. Amanda T Roten, Nathaniel L Baker, Sudie Back, Kevin M Gray. Marijuana Craving Trajectories in
an Adolescent Marijuana Cessation Pharmacotherapy Trial. Addictive Behaviors. 2013 March; 38:1788‐
1791. Michael E. Saladin, Kevin M. Gray, Aimee L. McRae‐Clark, Steven D. LaRowe, Sharon D. Yeatts, Nathaniel L Baker, Karen J. Hartwell, and Kathleen T. Brady. A Double Blind, Placebo‐Controlled Study of the Effects of Post‐Retrieval Propranolol on Reconsolidation of Memory for Craving and Cue Reactivity in Cocaine Dependent Humans. Psychopharmacology. 2013 April; 226 (4): 721‐737 Kimber L Price, Nathaniel L Baker, Aimee McRae‐Clark, Michael E Saladin, Stacia M DeSantis, Elizabeth Santa Ana, Kathleen T Brady. A Randomized, Placebo‐controlled Laboratory Study of the Effects of D‐
cycloserine on Craving in Cocaine‐Dependent Individuals. Psychopharmacology. 2013 April; 226 (4): 739‐746 Maria F Lopes‐Virella, Nathaniel L Baker, Kelly J Hunt, Patricia A Cleary, Richard Klein, Gabriel Virella, and the DCCT/EDIC Research Group. Baseline Markers of Inflammation are Associated with Progression to Macroalbuminuria in Type 1 Diabetic Subjects. Diabetes Care. 2013 August; 36 (8); 2317‐2323. Aimee L McRae‐Clark, Nathaniel L Baker, Megan Moran‐Santa Maria, Kathleen T Brady. Effect of Oxytocin on Craving and Stress Response in Marijuana‐Dependent Individuals: A Pilot Study.
Psychopharmacology. 2013 August; 228:623‐632. - 11 Last Updated 6/25/2015
Baker, Nathaniel L 31. 32. 33. Stacia M DeSantis, Dipankar Bandyopadhyay, Nathaniel L Baker, Patrick Randall, Raymond Anton, Jim J Prisciandaro. Modeling Longitudinal Data in Substance Use Clinical Trials: An Application to the COMBINE Study. Drug and Alcohol Dependence. 2013 September; 132:244‐250. Alicia J Jenkins, Jeremy Yu, Petar Alaupovic , Arpita Basu, Richard L Klein, Maria Lopes‐Virella, Nathaniel L Baker, Kelly J Hunt, Daniel T Lackland, W. Timothy Garvey, , Timothy J Lyons, and the DCCT/EDIC Research Group. Apolipoprotein‐defined Lipoproteins and Apolipoproteins: Associations with Abnormal Albuminuria in Type 1 Diabetes (DCCT/EDIC Cohort). Journal of Diabetes and its Complications. 2013 September; 27:447‐453. A. Lee Lewis, Nathaniel Baker, Matthew Carpenter, Erin Klintworth, Kevin M Gray. Does physician continuity within a clinical trial increase retention and compliance among adolescent smokers? Adolescent Psychiatry. 2013; 3:195‐9.* 34. Erin A McClure, Michael E Saladin, Nathaniel L Baker, Matthew J Carpenter, and Kevin M Gray. Smoking topography and abstinence in adult female smokers. Addictive Behaviors. 2013 December; 38:2833‐
2836. 35. Kelly J Hunt, Nathaniel L Baker, Patricia Cleary, Jye‐Yu Backlund, Gabriel Virella, Maria F Lopes‐Virella, and the DCCT /EDIC Research Group. Oxidized LDL and AGE‐LDL in Circulating Immune Complexes strongly Predicts Progression of Internal Carotid Artery IMT in Type 1 Diabetes. Atherosclerosis. 2013 December; 231:315‐322. 36. Eric M Graham, Andrew M Atz, Kimberly E McHugh, Ryan J Butts, Nathaniel L Baker, Robert E Stroud, Rachael L Deardorff, Scott T Reeves, Scott M Bradley, Francis X McGowan, Jr., Francis G Spinale. Preoperative Steroid Treatment Does Not Improve Markers of Inflammation Following Cardiac Surgery in Neonates. The Journal of Thoracic and Cardiovascular Surgery. 2014 March; 147(3): 902‐908. 37. Maria F Lopes‐Virella, Nathaniel L Baker, Kelly J Hunt, Patricia A Cleary, Richard Klein, Gabriel Viralla, and the DCCT/EDIC Research Group. Response to comment on Lopes‐Virella et al. baseline marker of inflammation are associated with progression to macroalbuminuria in type 1 diabetic subjects. Diabetes Care. 2014, May; 37(5): e108‐e109. 38. Erin A McClure, Nathaniel L Baker, Kevin M Gray. Cigarette smoking during an N‐acetylcysteine‐assisted cannabis cessation trial in adolescents. The American Journal of Drug and Alcohol Abuse. 2014 July; 40(4): 285‐291. 39. Richard L Klein, Samar M Hammad, Nathaniel L Baker, Kelly J Hunt, Mohammed M Al Gadban, Patricia A Cleary, Gabe Virella, Maria F Lopes‐Virella, and the DCCT/EDIC Research Group. Decreased Plasma Levels of Select Very Long Chain Ceramide Species are Associated with The Development of Nephropathy in Type 1 Diabetes. Metabolism. 2014 October; 63:1287‐1295. 40. Megan Moran Santa‐Maria, Aimee McRae‐Clark, Nathaniel L Baker, Viswanathan Ramakrishnan, Kathleen T Brady. Yohimbine Administration and Cue‐Reactivity in Cocaine Dependent Individuals . Psychopharmacology. 2014 October; 231 (21); 4157‐4165. 41. Erin A McClure, Nathaniel L Baker, Cassandra D Gipson, Matthew J Carpenter, Amanda Roper, Brett Froeliger, Peter W Kalivas, Kevin M Gray. An Open Label Pilot Trial of N‐acetylcysteine and Varenicline in Adult Cigarette Smokers. The American Journal of Drug and Alcohol Abuse. 2015 January; 41(1): 52‐56. - 12 Last Updated 6/25/2015
Baker, Nathaniel L 42. Hussein A Rajab, Nathaniel L Baker, Kelly J Hunt, Richard Klein, Patricia A Cleary, Gabriel Virella, Maria F Lopes‐Virella, and the DCCT/EDIC group of Investigators. The Predictive Role of Markers of Inflammation and Endothelial Dysfunction on the course of diabetic Retinopathy in Type 1 Diabetics Subjects. The Journal of Diabetes and its Complications. 2015 January; 29:108‐114. 43. Amanda T Roten, Nathaniel L Baker, Alan Boyd, Kevin M Gray. Cognitive Performance in a Placebo‐
Controlled Pharmacotherapy Trial for Youth with Marijuana Dependence. Addictive Behaviors. 2015 June; 45:119‐123. 44. Megan Moran Santa‐Maria, Nathaniel L Baker, Viswanathan Ramakrishnan, Aimee McRae‐Clark, Kathleen T Brady. Impact of acute guanfacine administration on stress and cue reactivity in cocaine‐
dependent individual. The American Journal of Drug and Alcohol Abuse. 2015 March; 41(2): 146‐152. 45. Michael E Saladin, Erin A McClure, Nathaniel L Baker, Matthew J Carpenter, Viswanathan Ramakrishnan, Karen J Hartwell, Kevin M Gray. Increasing Progesterone Levels are Associated with Smoking Abstinence in Free Cycling Women Smokers Receiving Brief Pharmacotherapy. Nicotine and Tobacco Research. 2015 April; 17(4):398‐406. 46. Cheryl P Lynch, Nathaniel L Baker, Jeffrey E Korte, Jill G Mauldin, Maria E Mayorga, Kelly J Hunt. Increasing Prevalence of Diabetes During Pregnancy in South Carolina. Journal of Women’s Health. 2015 April; 24(4): 316‐323. 47. Leonardo Bonilha, Jens H Jensen, Nathaniel L Baker, Jesse L Breedlove, Travis Nesland, Jack J Lin, and Daniel L Drane. The Brain Connectome as a Personalized Biomarker of Seizure Outcomes after Temporal Lobectomy. Neurology 2015 May; 84(18): 1846‐1853. 48. Kevin M Gray, Erin A McClure, Nathaniel L Baker, Matthew J Carpenter, Michael E Saladin, Viswanathan Ramakrishnan, and Kathleen T Brady. An Exploratory short‐term double blind randomized trial of varenicline versus nicotine patch for smoking cessation in women. Addiction 2015 June; 110: 1027‐
1034. 49. Kelly J Hunt, Nathaniel L Baker, Patricia A Cleary, Richard Klein, Gabriel Virella, Maria F Lopes‐Virella, and the DCCT/EDIC Research Group. Longitudinal association between endothelial dysfunction, inflammation and clotting biomarkers with subclinical atherosclerosis in type 1 diabetes: an evaluation of the DCCT/EDIC cohort. Diabetes Care 2015 July; 38:1281‐1289. 50. Aimee L McRae‐Clark, Nathaniel L Baker, Susan C Sonne, C Lindsay DeVane, Amanda Wagner, and Jessica Norton. Concordance of direct and indirect measures of medication adherence in a treatment trial for cannabis dependence. (2015) The Journal of Substance Abuse Treatment. Non‐Peer Reviewed Articles 1. Nathaniel L Baker, Kevin M Gray. Jittering: A SAS® Macro to Shift Overlapping Plots. Proceedings of the Southeast SAS Users Group (SESUG) 2009 Conference; Statistics and Data Analysis Paper 002 (SD‐002). Cary, NC: SAS Institute Inc. October 2009. - 13 Last Updated 6/25/2015
Baker, Nathaniel L Manuscripts Submitted and in Preparation: 1.
Aimee L McRae‐Clark, Nathaniel L Baker, Rickey E Carter, Kimber L Price, Kathleen T Brady. Sex Differences in Stress‐Elicited Reactivity and Situations for use in Marijuana‐Dependent Individuals. Submitted to Drug and Alcohol Dependence. 2.
Megan M. Moran‐Santa Maria, Aimee L. McRae‐Clark, Nathaniel L. Baker, Madison Hyer, Chantelle Ferland and Kathleen Brady. Impact of endogenous progesterone on reactivity to yohimbine and cocaine cues in cocaine‐dependent women. Submitted to Psychoneuroendocrinology 3.
Michael E. Saladin, Kevin M. Gray, Aimee L. McRae‐Clark, Steven D. LaRowe, Sharon D. Yeatts, Nathaniel L Baker, Karen J. Hartwell, and Kathleen T. Brady. PTSD/reconsolidation. Submitted to. 4.
Julianne Flanagan, Nathaniel L Baker, Sudie E Back, Megan M Moran Santa‐Maria. The Moderating Effect of Adverse Childhood Experiences on the Association between Intranasal Oxytocin and Social Stress Reactivity among Individuals with Cocaine Dependence. Under Revision for Psychiatry Research. 5.
Aimee L. McRae‐Clark, Nathaniel L. Baker, Kevin M. Gray, Therese K. Killeen, Amanda M. Wagner, C. Lindsay DeVane, and Jessica Norton. Buspirone for treatment of cannabis dependence: a randomized, placebo‐controlled trial. Submitted to Drug and Alcohol Dependence. 7. Christina M Sheerin, Nathaniel L Baker, Ananda B Amstadter, and Aimee L McRae‐Clark. Oxytocin administration in marijuana users moderated by adverse childhood events. Submitted to Psychopharmacology. 8. Erin McClure, Nathaniel L Baker, Matthew J Carpenter, Frank A Treiber, Kevin M Gray. Attitudes and acceptability of remote monitoring technology among adolescents enrolled in smoking cessation treatment. Submitted to… 9. Maria F Lopes‐Virella, Kelly J Hunt, Nathaniel L Baker, Gabriel Virella, VADT Research Group. High levels of AGE‐LDL, MDA‐LDL, and IgG oxLDL Antibodies in Circulating Immune Complexes Predict Macroalbuminuria in Patients with Type 2 Diabetes. Submitted to… 10. Aimee L. McRae‐Clark, Nathaniel L. Baker, Kevin M. Gray, Therese K. Killeen, Amanda M. Wagner, C. Lindsay DeVane, and Jessica Norton. Vilazadone for treatment of cannabis dependence: a randomized, placebo‐controlled trial. Submitted to ... Conference, Symposium, Continuing Education and Short Corse Attendance 2003 Joint AMS / MAA SE Regional Conference, Clemson SC 2005 Joint AMS / MAA National Meeting, Atlanta GA 2008 Southeast SAS Users Group Meeting, St. Petersburg FL 2009 Frontiers in Quantitative Methods for Cancer Research, Medical College of Georgia Short Course, Augusta GA - 14 Last Updated 6/25/2015
Baker, Nathaniel L 2009 Southeast SAS Users Group Meeting, Birmingham AL (Oral Presenter) 2010 American Diabetic Association Scientific Symposium, Orlando FL (Oral Presenter) 2011 American Diabetic Association Scientific Symposium, San Diego CA (Oral Presenter) 2012 American Diabetic Association Scientific Symposium, Philadelphia PA (Oral Presenter) 2013 Workshops in Quantitative Research Methodology, Summer Research Institute, Short Course on Longitudinal/Multilevel Modeling, May, 2013, MUSC, Charleston, SC 2013 Statistics in Medicine (HRP258‐MOOC; Dr. Kristin Sainani), Certificate with Distinction, June 10‐
Aug 16, 2013 Stanford University 2013 International Conference on Health Policy Statistics, Chicago IL 2013 ICHP Workshop on Extended Mixed Models for Ecological Momentary Assessment (EMA) Data, Dr. Don Hedeker, October 2013, Chicago IL 2014 Statistical Analysis of fMRI Data (MOOC; Dr. Martin Lindquist), Certificate with Distinction, February 24‐April 6, Johns Hopkins University 2015 American Diabetic Association Scientific Symposium, Boston MA (Poster Presenter) Current Extramural Funding R01 DK099177‐01A1 07/01/2013‐6/30/2018 NIH/NIDDK $383,666 Annual Direct Costs Protective Effect of Ceramide in Diabetic Nephropathy This proposal intends to study the role and response of ceramides and sphingolipids in the development and progression of nephropathy in type 1 diabetes. Role: Co‐Investigator 1K24 DA038240‐01 (McRae‐Clark, PI) 7/1/2014‐6/30/2019 NIH/NIDA Mid‐Career Award in Patient Oriented Drug Abuse Research The objective of this Midcareer Investigator Award in Patient‐Oriented Research is to provide support for protected time so that Dr. Aimee McRae‐Clark can develop a more formal, intensive program of mentored clinical research training and career development activities to promote junior scholars in the area of drug abuse and addiction. Particular emphasis will also be placed on increasing the participation of underrepresented minorities conducting patient‐oriented research. Role: Statistician 1R01 DA035247‐01 04/01/2013 – 03/31/2018 NIH/NIDA $347,689 Annual Direct Costs Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving, Reactivity & Use The purpose of this project is to investigate the augmentation of the disruption of reconsolidation (DoR) effect by (a) doubling the number of propranolol medicated retrieval sessions of CCE, and (b) increasing the dose of propranolol. This is expected to enhance the response dampening ‘signal’ detected in the R21 and assess its durability, generalizability and effects on cocaine use. Role: Co‐Investigator P50 DA016511‐11 09/01/2012 – 07/31/2017 NIH/NIAMS $750,000 Annual Direct Costs Specialized Center of Research (SCOR) on Sex and Gender Factors Affecting Women's Health The purpose of this project is to study gender differences in response to cocaine related cues and negative emotional states in men and women. - 15 Last Updated 6/25/2015
Baker, Nathaniel L Role: Co‐Investigator 1U01 DA031779‐01A1 06/01/2012‐05/31/2017 NIH/NIDA $428,356 Annual Direct Costs A Randomized Trial of Varenicline for Adolescent Smoking Cessation This primary goal of the study will be to examine the efficacy of varenicline, compared with placebo, for smoking cessation in adolescent smokers. Secondarily, the study will assess the safety of varenicline in an adolescent population. Role: Co‐Investigator BX0001683‐01 04/01/2013‐03/31/2017 Biomedical Lab R&D Merit $199,300 (1st year; 150,000/remaining) Department of Veterans Affairs Modified LDL, Immunity and the Development of Diabetic Complications This project will compare the activation patterns of macrophages exposed to modified LDL immune complexes (IC) and the effect of these IC on the survival/ apoptosis of the same cells. In this project we will also perform measurements of novel plaque instability biomarkers in a subgroup of the VADT cohort to determine whether or not they can identify patients at high risk for acute MI. Role: Statistician 1I01 BX001282‐01A2 (Brady, PI) 10/01/2014‐09/30/2018 Psychological Health and social Reintegration RR&D Merit $250,000 Department of Veterans Affairs Mindfulness‐Based Recovery in Veterans with Substance Use Disorder Role: Co‐Investigator 1R21 DA035993‐01 08/01/2013 – 07/31/2015 NIH/NIDA $150,000 Annual Direct Costs Reducing Smoking Cue Reactivity & Behavior Via a Retrieval‐Extinction Mechanism This study will examine the effects of two sessions of retrieval‐extinction training in smokers who are making a quit attempt. Effects of the training on smoking craving and cue reactivity, and on indices of smoking, will be assessed. It is expected that the smoking‐cue retrieval feature of this training will result in significant and enduring reductions in craving and reactivity to smoking cues and have a favorable impact on smoking. Role: Co‐Investigator 5R01 DA026782‐04 08/15/2009‐05/31/2014 (NCE 2015) NIH/NIDA $240,075 Annual Direct Costs Buspirone Treatment for Marijuana Dependence Results from this study could lead to the development of a new pharmacotherapy for marijuana dependence. Increase our knowledge of a potential genetic biomarker for prediction of outcomes, and improve clinical trial methodology in the investigation of marijuana dependence. Role: Statistician 1R21 DA034089‐01 NIH/NIDA Vilazodone Treatment for Marijuana Dependence 07/01/2012‐05/31/2014 (NCE 2015) $150,000 Annual Direct Costs - 16 Last Updated 6/25/2015
Baker, Nathaniel L Results from this study could lead to the development of a new pharmacotherapy for marijuana dependence and increase our knowledge of a potential genetic biomarker for prediction of outcomes. Role: Statistician K01 DA036739 07/01/2014‐06/30/2019 NIH/NIDA Technological Innovations for the Remote Monitoring of Smoking in Adolescents This career development grant will develop Dr. McClure’s expertise in mobile health and adolescent smoking and addiction, and will evaluate the accuracy and acceptability of a remote monitoring system to detect smoking and relapse in adolescents. Priority/impact score of 11, 2nd round. Role: co‐Investigator American Cancer Society Institutional Research Grant at MUSC, Pilot Project 04/01/2014‐12/31/2014 Technological Innovations for the Remote Monitoring of Smoking in Adolescents This pilot project will develop and evaluate a remote monitoring technology to detect smoking and relapse in adolescents. Role: Statistician PENDING R01 Unumbered (Hanlon, PI) 07/01/2014‐06/30/2019 NIH/NIDA $250,000 Annual Direct Costs The purpose of this longitudinal neuroimaging study is to determine the relationship between functional connectivity in executive control regions (namely, the dorsolateral prefrontal cortex) and both proximal and extended outcomes in treatment‐seeking cocaine users. The fundamental neuroscience knowledge gained will be used to develop new evidence‐based brain stimulation treatment strategies (e.g., repetitive TMS) to enhance the integrity of these circuits and subsequent outcomes in traditional treatment programs. Role: Statistician (10% Effort) 4R44 DA036277‐02 (Flores, PI; McRae‐Clark, Subcontract PI) 12/1/2014‐2/29/2016 SBIR/NIDA Smart Capsule for Automatic Adherence Monitoring This SBIR collaboration is supporting the development and testing of an electronically chipped capsule to enable compliance monitoring in a drug dependent population. Role: Co‐Investigator (10% effort) N44 DA‐14‐2232 (PI: Darmanjian; McRae‐Clark, Subcontract PI) 12/1/2014‐2/29/2016 SBIR/NIDA A Phase II Randomized Trial to Assess the Effectiveness and Safety of the ID‐Cap System for Medication Ingestion Monitoring and Enhancing Adherence This SBIR collaboration is incorporating biometric identification into compliance enhancement interventions in a drug dependent population. Role: Co‐Investigator (10% effort) R34 Unnumbered 07/01/2013‐06/30/2016 NIH/NIDA $182,596 Annual Direct Costs Mindfulness Meditation for Women with PTSD and SUD in a Community Setting - 17 Last Updated 6/25/2015
Baker, Nathaniel L This study explores the use of Mindfulness Based Relapse Prevention (MBRP), an efficacious eight session group therapy for the treatment of individuals with substance use disorders, in women with comorbid PTSD and SUD enrolled in community substance abuse treatment. Role: Co‐Investigator (15% Effort) R21 DK099177 07/01/2014‐06/30/2016 NIH/NIMH $150,000 Annual Direct Costs Vigabatrin for the Treatment of Posttraumatic Stress Disorder The proposed study is a randomnized double‐blind trial to preliminarily evaluate the efficacy and safety of vigabatrin in individuals with PTSD. Role: Co‐Investigator (10% Effort) Recently Completed U24 DK076169 10/01/2013‐09/30/2014 NIH/NIDDK through Georgia Regents University (DiaComp) $47,816 Annual Direct Costs Association of Plasma Deoxysphingolipids with Neuropathy in the DCCT/EDIC Cohort The aim of this proposal is to generate pilot data investigating the association of deoxysphingolipids with neuropathy in type 1 diabetic patients. Role: Statistician N01 DA‐11‐1145 10/01/2013‐10/01/2014 NIH/NIDA AACAP Resident Research Award Cognitive Performance in an Adolescent Marijuana Cessation Pharmacotherapy Trial/ Passed Through the American Academy of Child Psychiatry The aim of this proposal is to examine cognitive performance among adolescents with marijuana dependence enrolled in a pharmacotherapy trial Role: Statistician 5R01DK081352‐03 09/01/2008‐07/31/2012 DHHS/NIH/NIDDK $357,032 Biomarkers of Vascular Disease Progression in Type 1 Diabetes Mellitus The goal of this research is to elucidate the value of selected biomarkers in predicting the development of micro‐ and macro‐vascular complications in Type 1 diabetes and to determine if several risk factors, some unique to diabetes, may interact to augment vascular risk. Role: Statistician R01DK088778 07/01/2010‐06/30/2012 NIH/NIDDK $125,000 Longitudinal Assessment of LDL Immune Complexes and Type 1 Diabetes Complications The goal of this project is to complete secondary data analysis to study the epidemiology of LDL immune complex (IC) measurements in relation to micro‐ and macro‐vascular complications in 520 DCCT/EDIC participants with these biomarkers measured at four time points spanning 22 years. Role: Statistician 5P50DA016511‐10 NIH/NIDA SCOR on Sex and Gender Factors Affecting Women’s Health 09/30/2002‐06/30/2012 $568,161 - 18 Last Updated 6/25/2015
Baker, Nathaniel L This center grant is funded through a partnership between ORWH and NIH to develop and conduct innovative, interdisciplinary and collaborative research investigating substance use disorders among women. Role: Statistician - 19 Last Updated 6/25/2015