MedicalAlumni M A G A Z I N E spring 2007 volume 48 | no 1 Flags of Our Professors Behind the battles: How UCSF faculty and alumni cared for the soldiers of World War II Also inside... S T E M C E L L R E S E A R C H AT U C S F | ADVISORY COLLEGES | CLASS NOTES Inside MedicalAlumni M A G A Z I N E Spring 2007: Volume 48, Number 1 Editor-in-Chief: Kenneth H. Fye, MD ’68 Managing Editor: Anne Kavanagh Contributing Editors: Patrick Delahunt, Jean Murray, Lyn Oswald Writers: Carli Cutchin, Anne Kavanagh, Jean Murray Photographers: Noah Berger, Corbis / Robert F. Sargent, Harras Zaid Editorial AssistantS: Jody Duncan, Gina Martinez DesignER: Laura Myers Design departments 1 from the editor 2 president’s letter 12 class notes features 3 Flags of Our Professors Faculty and alumni with UCSF’s 30th General Hospital served the wounded and the nation during World War II. Administrative Council 2006–2007 OFFICERS David N. Schindler, MD ’66, President; Gordon L. Fung, MD ’79, President-Elect; H. John Blossom, MD ’70, Vice President (Central California); Ronald P. Karlsberg, MD ’73, Vice President (So. California); Lawrence Lustig, MD ’91, Secretary/Treasurer COUNCILORS AT LARGE Robert J. Albo, MD ’59; Kenneth M. Bermudez, MD ’92; Caley Castelein, MD ’98; Neal H. Cohen, MD ’71; Timothy J. Crowley, MD ’80; Kenneth H. Fye, MD ’68; Ruth Goldstein, MD ’79; Lawrence Hill, MD ’67; Donna Hoghooghi, MD ’98; Tomas Magana, MD ’95; Mary Eleanor Margaretten, MD ’03; Willis Navarro, MD ’90; Harlan B. Watkins, MD ’63; Frederick Parris, MD, President, Association of the Clinical Faculty; Robert C. Lim, MD ’60, Councilor Emeritus 10 Stem Cell Research Forges Ahead 11 UCSF Advisory Colleges UCSF scientists pursue the promise of stem cells, obstacles or no. PAST PRESIDENTS Judith A. Luce, MD ’74; John Fletcher, MD ’57; Eileen Z. Aicardi, MD ’74 HOUSESTAFF REPRESENTATIVE Jafi Lipson, MD ’03 STUDENT REPRESENTATIVES Alumna finds fulfillment as mentor to medical students. Esther Hong, MS3; Daniel Orjuela, MS2 EX-OFFICIO J. Michael Bishop, MD, Chancellor David A. Kessler, MD, Dean, UCSF School of Medicine UCSF School of Medicine Medical Alumni Association 745 Parnassus Avenue, Box 0970 San Francisco, CA 94143-0970 Tel: 415/476-4723 Toll free: 866/904-2400 Fax: 415/476-9570 Email: [email protected] Website: www.ucsfalumni.org © 2007 UCSF School of Medicine, MAA. All rights reserved. O N T H E C O V E R : On D-Day, June 6, 1944, a landing craft just vacated by invasion troops points toward a fortified beach on the Normandy Coast. American soldiers wade to shore fighting heavy machine-gun fire. Many casualties of this and other World War II battles were treated by UCSF members of the 30th General Hospital. See story, page 3 Contact us! Your letters are welcome. Write to: UCSF Medical Alumni Magazine, Letters to the Editor 745 Parnassus Avenue, Box 0970, San Francisco, CA 94143-0970 Or use the new reply envelope in the center of the magazine. You may also email your letter to: [email protected]. Please type “Letter to the Editor” in your subject field. F rom the E ditor The White Coat Ceremony O ne of the medical student events sponsored by the Medical Alumni Association is the White Coat Ceremony. During the ceremony, first-year students are officially admitted to their “college” within the medical school curriculum and presented with the traditional white coat of a Medical House Officer. Then the students, along with various deans of the medical school, chairs of the curriculum “colleges,” representatives of the Medical Alumni Association, and sundry medical school dignitaries, take the Louis Lasagna Physician’s Oath. Selected speakers remind the attendees of the new responsibilities and privileges inherent in becoming a physician. The audience consists of family and friends of the students being honored. The ceremony officially recognizes the passage of the student from general membership in the community at large into the select family of practitioners of the art and science of medicine. The white coat itself symbolizes and is meant to cement the separation of the physician, as an esteemed professional, from the lay community to be served. As editor of the UCSF Medical Alumni Magazine, I was allowed to attend this year’s ceremony. It was a joyous and moving experience. However, as a graduate of the Class of 1968, a “child of the ’60s,” I could not but note the irony of the event. There was no White Coat Ceremony in 1964 when I was a freshman. During orientation we learned the locations of the buildings and classrooms that would be the center of our educational experience for the next four years. We all waited in line to get our microscopes and bones (full skeletons disarticulated to neatly fit into black boxes, suitable for home study) and, in fact, at the end of the line we all received a long white lab coat that proved to be extremely valuable during gross anatomy. After getting our coats “Why have the white coat and the ceremony again taken on such significance? . . . There was no White Coat Ceremony in 1964 when I was a freshman. After getting our coats we just went to class.” Ken Fye, MD ’68 we just went to class. At the time there was actually an unspoken movement to avoid wearing the white coat, because the separation between “the Doctor” and his patient, which the white coat symbolized, was not consistent with the anti-establishment communalism of the times. If we ever thought about the white coat it was with a hint of derision. The irony is how times and dress codes have changed. Why have the white coat and the ceremony again taken on such significance? It may simply be the cyclic nature of things and a return to tradition. However, the coat and the ceremony may also reflect an attempt to protect the image of medicine as a “profession.” Webster’s New Twentieth Century Unabridged Second Edition Dictionary defines a profession as “a vocation or occupation requiring advanced training in some liberal art or science, and usually involving mental rather than manual work, - - -; especially medicine, law or theology (formally called the learned professions).” By that definition the average Las Vegas bookie or any experienced maitre d’hotel would be a professional. I maintain that the term “profession” implies more than just training—it implies commitment. The commitment | medical alumni magazine From the Editor | continued I envision is to service, to excellence, and to completion. The terms “service” and “excellence” are self evident. The term “completion” needs some clarification. By that, I mean that professions are task oriented, while non-professional vocations are time oriented. Most jobs are defined by the number of hours spent working. Work begins at 8 a.m. and ends at 5 p.m., with an hour off for lunch and a 15-minute break in the morning and the afternoon. The medical profession has traditionally been defined by the task at hand (such as performing an unscheduled emergency surgery or treating a patient with a massive myocardial infarction), with the time spent accomplishing the task or achieving the goal being only a secondary consideration. That is clearly no longer the case. Medical training hours have been legally limited. The amount of time trainees can spend in the hospital is strictly controlled, and new physicians actively seek jobs with circumscribed working hours. The new emphasis on time rather than task does allow physicians a more well-rounded personal life. However, it also blurs the definition of medical professionalism. At the end of your shift you leave, whether or not the diagnosis is made or the appropriate therapy initiated. The white coat and its attendant ceremony is a way of re-establishing the sense of commitment and accomplishment that should define what we do. It is a way of reminding us that, despite the restrictions on time with which we have to deal, our success is still defined by what we do for our patients, not how long it takes us to do it. It is a way of protecting the sense of “professionalism” that distinguishes medicine from other vocations and even other professions. Despite my personal sense of irony, I think the White Coat Ceremony, being a new tradition to help define an ancient profession, is well worth nurturing. Kenneth H. Fye, MD ’68 | spring 2007 F rom the president Greetings While UCSF campus achievements appear frequently in today’s San Francisco headlines, the University’s long tradition of service reaches back to the very beginnings of the City. From the Gold Rush days to the 1906 earthquake to the two world wars and beyond, UCSF has responded to the needs of local citizens and society at large. I am pleased that this issue of the UCSF Medical Alumni Magazine explores how alumni, faculty, and students responded to the call of the nation during World War II. When the United States entered the war, hundreds of physicians, nurses, and enlisted men from UCSF traveled to Europe and the South Pacific to support American troops. Many served with the 30th General Hospital, UCSF’s military unit. On campus, classes were compressed so students could complete their MD degrees more quickly, and remaining faculty worked overtime. Our predecessors, renowned professors such as Clayton Mote and Robert Crede, who you will read about in this issue, served with the 30th General Hospital for the duration of the war. They returned to their practices and UCSF to teach— often as volunteers—sharing the deep knowledge they gained from their wartime service. They gave back to their country, community, patients, and to this University. Their dedication influenced a generation of UCSF students, making us better physicians and people. My own father, Meyer Schindler, served overseas with the 30th General Hospital. He came back from the war with many stories, but the biggest lesson he shared with our family was the importance of giving back to the community and to the nation. The lessons from UCSF’s history are important to all of us. David Schindler, MD ’66 MAA President 2006–2007 COVER STORY Flags of Our Professors How UCSF faculty and alumni cared for the soldiers of World War II by Anne Kavanagh In the summer of 1944, a group of young faculty and alumni from UCSF steamed across the English Channel. They landed at Utah Beach in Normandy, France, where Junior officers outside their barracks in England, 1943. some of the most bitter fighting of World War II had raged just weeks earlier. With full backpacks, they marched for eight miles through the thick mud. After boarding Army trucks, they journeyed onward amid machine-gun fire. Every few miles, they were forced to jump for cover in the muddy ditches. They would soldier on to serve the wounded—and their country— as part of the 30th General Hospital, the military unit of UCSF. The impact of their extraordinary wartime experiences would ripple across UCSF for years: in their own lives and the lives of the students they would return to teach. June 1942 – October 1945 ENGLAND • FRANCE • BELGIUM | medical alumni magazine Torpedoed on the Atlantic O June 1942 Answering the Call of a Nation T he 30th unit was born just prior to World War I. In anticipation of that war, faculty at several East Coast medical schools began organizing into military base hospitals. UCSF joined this vanguard, organizing Base Hospital No. 30, which later served in France. When the Japanese bombed Pearl Harbor, catapulting the United States into World War II, UCSF faculty and physicians reactivated the unit as the 30th General Hospital. Almost all the medical, surgical, and dental staff who joined were from UCSF, as was the chief of nursing. Many were alumni. In June 1942, the 28 officers, 325 enlisted men, and 70 nurses of the 30th departed for England from New York aboard the Queen Elizabeth (pictured above). They were to cross the Atlantic during the height of the German submarine campaign, when more Allied shipping was lost due to enemy action than at any other time during the war. Amid the bustle and confusion, a small group of medical officers arrived too late to board the Queen Elizabeth. They were sent to Galveston, Texas, and booked aboard a Dutch vessel, the Jagersfontein. Theirs would prove a fateful journey. ne of the officers on board the Jagersfontein, Meyer Schindler, MD ’38, kept a diary. On their ninth day at sea, he wrote: “At 3:50 a.m. was awakened by a dull thud and a jar. It felt like the Jagersfontein had rammed something. But I knew it must have been a torpedo for you could smell the cordite. I immediately grabbed my life belt and ran to lifeboat No. 1 in my pajamas. I was on the starboard side when somebody yelled the ship had been hit on the port side aft. ... I knew the ship was thru and it was just a matter of time before we were in that inky water.” They were ordered to abandon ship and board lifeboats. The submarine reappeared about 45 minutes later, firing another torpedo into the Jagersfontein. Schindler continues: “In exactly 45 seconds, the ship was below the surface of the ocean. ... At 9:15 a.m., the sub surfaced not more than 250 yards from our lifeboats. We all thought they would machine-gun us because we were military personnel. However, the Germans nonchalantly went about their business picking up debris from the ship. ... The sub remained on the surface for about 45 minutes, then steamed off.” The following day, a Swiss ship rescued them about 500 miles off Bermuda. The officers eventually returned to New York and then crossed the Atlantic on a British ship. After a few more close calls, they arrived in Scotland and reunited with the others. At left: the men watch their sinking ship from lifeboats; above: the Jagersfontein sinks Influencing a generation Numerous officers of the 30th General Hospital returned to UCSF, serving as clinical faculty for years. They are remembered by many as a dedicated and accomplished group, whose worldwide experience accelerated their capacity to teach and helped shape a generation of physiciansin-training. Equally dedicated were those who stayed behind at UCSF during the war, working overtime to fill the many vacancies in the teaching hospitals. The following are just a few of the World War II faculty alumni whose legacies live on at UCSF. | spring 2007 Clayton Mote, MD ’30 “Clayton was the ‘gold standard’ for practicing internal medicine,” says surgeon F. William Heer, MD ’56, a former student and then UCSF faculty colleague of Mote’s. Mote served with the 30th as a lieutenant colonel and as chief of medicine from 1942 until 1946. He was on the clinical faculty at UCSF from 1931 until 1972. For 15 years, he taught physical diagnosis to sophomore medical students. “When I got an ‘A’ in Mote’s class,” Heer says, “it was one of the proudest days of my life.” A no-nonsense man who stood ramrod straight and rarely cracked a smile, Mote “did not tolerate shortcomings,” recalls Heer. Long before the era of CAT scans, Mote used his senses and uncanny ability to employ deductive reasoning in Officers of the 30th General Hospital in Mansfield, England, with visitor Howard Naffziger (in civilian clothes), chair of the UCSF Department of Surgery and Consultant for Neurosurgery, U.S. Army ENGLAND Serving the Wounded —with Ingenuity A fter disembarking, the unit took a train to their hospital site in Mansfield in the heart of Britain’s coal mining district. The 30th was the first American military base hospital in England and began admitting patients right away. But supplies and equipment were scarce, resulting in some novel improvisations. For example, the operating room had no suction apparatus to remove blood during surgery. Dental alumnus Stanley Erpf devised one out of bicycle pumps, operated by two corpsmen. In the dental clinic, footoperated drills were used. Early fractured jaws were immobilized with fuse wire and Stanley Erpf in the dental clinic buck shot. Another instance of UCSF ingenuity involved artificial eyes, which were in high demand. Glass eyes broke frequently and took months to replace. Using his experience with dental plastic, Erpf developed an unbreakable eye out Clayton Mote (left) with Charles Rosson in Mansfield, England, 1943 diagnosing conditions. When other physicians were stymied making a diagnosis, they would call the “Motoscope,” says Heer. “Everyone was in awe of him.” Another former student, Gerald P. Rodriguez, MD ’66, wrote the following about Mote when he was named 1991 UCSF Alumnus of the Year: “Our Class of 1966 met Dr. Mote at the Laguna Honda Hospital 27 years ago, in 1964. This spring semester course was terribly important of acrylic. He then set up the manufacturing process for this prosthesis for all of the Armed Forces. The hospital had 1,000 beds in its first year, and the staff treated a wide variety of illnesses and injuries. As in all wars, venereal disease posed a serious problem for the military personnel. Robert Crede, MD ’42, headed a successful effort to develop a new method for Nurse Eleanor Lindner treating syphilis in less than one (née Mench) mixing month compared to the usual penicillin in the 12-18 months. officers’ ward While in Mansfield, the medical staff first heard of a new “miracle drug” called penicillin. The top-secret pharmaceutical was to be used only for treating combat personnel, and the officers were astonished at penicillin’s effectiveness. “For the military, this new drug was like manna from heaven,” writes Meyer Schindler in The Thirtieth in Two World Wars, his book about the Meyer Schindler (right) with Clark Gable unit’s experiences. and exciting for us since it was our first real test of clinical medicine and our first real laying-of-hands on patients. At Dr. Mote’s urging, we began our first tentative steps at history-taking, and who of us will ever forget the cardinal steps of physical examination: inspection, palpation, percussion, and auscultation. “He was a task master. Best be prepared! When one of our class elected to ‘pass’ on one of his questions regarding the physical findings in a particularly arcane cardiac condition, Dr. Mote’s reply was instant and definitive: ‘Mr. X, you may decide not to answer this question, but you most certainly will not pass.’ “This dedicated medical educator and physician made many of us here feel those first pangs of pride as we began to look, feel, and act as doctors.” | medical alumni magazine One of three field hospitals set up to treat and evacuate front-line casualties during the invasion of Normandy, 1944 FRANCE Establishing a Tent Hospital O n June 6, 1944, the invasion of Normandy began. Several weeks later, the UCSF unit crossed the English Channel and landed at the Utah Beach bridgehead. They proceeded on an arduous and dangerous journey—part of the group almost strayed into the German line—to care for soldiers at a field hospital. They then set up a tent hospital in La Haye du Puit, receiving injured from the front line. During one 24-hour stretch, 320 casualties poured in. The surgical department mainly cleaned and closed wounds. Neuropsychiatry grappled with cases of battle fatigue. The medical department treated respiratory and gastrointestinal diseases, malaria, diarrhea, and other conditions. Constant rain caused problems with sanitation and drainage. Every night for a month, the German air force attacked the beachhead. Fragments of steel descended like rain during heavy anti-aircraft barrages and would have caused serious injuries if the staff hadn’t taken cover. They often found shell fragments in the morning that had pierced the tent hospital’s roof during the previous night’s battle. At right: Barbed wire on the invasion beach, Normandy. In the distance, British and American destroyers. Below: Wounded soldiers were brought to the tent hospital via ambulance trains—big buses fitted with sling beds for carrying both litter and semi-ambulatory patients. They operated near the front lines of combat. Influencing a generation Robert Crede, MD ’42 continued comprehensive ambulatory medical services at UCSF. Robert Crede served with In addition, he changed prethe 30th General Hospital and post-doctoral medical for three years and was education to emphasize a awarded the Bronze Star comprehensive approach to for Meritorious Service. all patient problems. “Bob He returned to UCSF as a resident in Medicine and later Crede was idolized by his students,” says colleague F. was chief resident. He also William Heer, MD ’56. “They became a full professor loved him and he loved them.” and held several leadership positions. Among his Robert Crede (left) with many accomplishments, Norman Sweet in Mansfield, Crede developed model England, 1943 | spring 2007 BELGIUM Surviving the Battle of Antwerp I n November 1944, the group left the tent hospital and traveled to St. Antonius, Belgium, near Antwerp. They took over a grim two-story stone structure, formerly a mental hospital. The Germans had launched their last major counterattack, and V-1 and V-2 rockets poured into the Antwerp area. One bomb even gyrated over the hospital before falling some distance away. The hospital was far from adequate, with insufficient heating and unchlorinated water. It was always dangerously understaffed with general surgeons, who were often sent on detached service to field and evacuation hospitals. When V-E Day arrived, their patient load actually increased. Casualties of the last German counterattack in 1944 arriving at the 30th General Hospital in St. Antonius, near Antwerp German V-1 “Buzz Bomb” behind the hospital GOING HOME Finally, in August 1945, it was officially announced that the 30th General Hospital would turn the installation over to another unit the next month. The war was over and the 30th could return to California. They sailed home on the SS Argentina, arriving in New York on October 4, 1945. Mary Olney, MD ’32 Nicknamed “St. Mary” by admiring colleagues, Olney was one of the hardworking faculty who stayed behind at UCSF during the war. She served as a clinical professor of pediatrics and chief of pediatrics at San Francisco General Hospital. “Mary worked night and day during those years,” recalls her former student, October 1945 Moses Grossman, MD ’46 (see story, next page). “She was a wonderful person who would do anything for children.” Olney later created the first summer camp for diabetic children. Olney taught by example, says Grossman, and was so inspiring that he changed his own career goal to pediatrics. Mary Olney worked day and night at the “homefront” in San Francisco. | medical alumni magazine Moses Grossman, MD ’46 One Student’s Wartime Experience Born in Russia, Moses Grossman, MD ’46, lived in China and began medical school in Hong Kong. He immigrated to the United States in 1941 and continued his medical studies at UCSF. “I wasn’t a citizen and with the war underway, it wasn’t clear what was going to happen to me,” he says. The dean of the UCSF School of Medicine traveled to Washington, D.C., to help secure Grossman’s citizenship. Because of the war, classes were accelerated and compressed from four full years into seven terms of sixteen weeks each, and the MD degree was granted before the year of internship. “We didn’t know any different, so the workload didn’t bother me,” he recalls. Grossman participated in an Army training program that paid for tuition and books, and he attended class in uniform. “I was grateful to the military for paying my way,” he says. After completing UCSF, he served in the Army for two years, including a stint in intelligence school. “They chose me because I spoke Russian,” Grossman explains. “It was a very interesting experience.” During the next 40 years, Grossman became a national leader in children’s health. He served as chief of pediatric services at San Francisco General Hospital, vice chair of the Department of Pediatrics at UCSF, and associate dean of the UCSF School of Medicine. Grossman was named UCSF Alumnus of the Year in 1985 and in 2001 he was awarded the UCSF Medal, the campus’s highest honor. | spring 2007 The 30th General Hospital received many commendations, including this one from President Harry Truman. UCSF School of Medicine Alumni and Faculty Members 30th General Hospital Walter Birnbaum, MD ’32 John Brown, MD ’35 John Castiglione, MD ’42 Leonid Cherney, MD ’34 Albert G. Clark, MD ’32 Edwin Clausen, MD ’36 Martin Covel, MD ’42 Robert Crede, MD ’42 James Elliot, MD ’36 Porter Forcade, MD (resident) Gordon Hein, MD Melford Jorgensen, MD ’38 Thomas Lennon, MD ’24 Maurice Leonard, MD Harold Lindner, MD ’33 Harold “Brick” Muller, MD ’29 Clayton Mote, MD ’30 Arthur Rice, MD ’34 Francis Rochex, MD ’28 Charles Rosson, MD ’31 Meyer Schindler, MD ’38 Adolph Segal, MD ’42 Ralph Soto-Hall, MD ’23 H. Brodie Stephens, MD Norman Sweet, MD ’38 James Thompson, MD Homecoming & Class Reunions School of Medicine Saturday, May 5, 2007 Please join in celebrating your reunion and experience the joy of reconnecting with old friends. Hear what’s new at UCSF, enjoy lunch with your class, applaud the next generation of leaders in medicine, and honor the Alumnus of the Year. Tour the new Mission Bay campus or visit your old stomping grounds. Reunions are special. Come back and learn why. Sponsored by the UCSF School of Medicine and the UCSF Medical Alumni Association RegisterToday! To register and pay online go to www.ucsfalumni.org and click on “Events.” JoinUs | medical alumni magazine RESEARCH Stem Cell Research at UCSF Accelerates, Despite Lags in State Funding b y Car li Cutchin A fter California voters passed Proposition 71 in 2004, the hopes of scientists and sufferers of ailments such as Parkinson’s and heart disease soared high. The first of its kind in the nation, the bill earmarked $3 billion over 10 years for stem cell research. Legal problems initially caused lags in distributing those funds. But UCSF pushed ahead, building its stem cell program with gifts from generous private supporters. In 60 labs across the UCSF campus, investigators are testing the promise of stem cells to repair or regenerate organs and tissues, potentially uncovering cures for many of life’s most intractable diseases. Their research owes its origins to one of UCSF’s own: Gail Martin, PhD, co-discovered and named embryonic stem cells in her University lab 25 years ago, a finding that would ignite a new era in medicine. Now, stem cell researchers are preparing to unite their diverse studies under one roof, thanks in part to a $16 million gift from Ray and Dagmar Dolby. With their labs located strategically throughout the new Institute for Regeneration Medicine building—to be housed at the Parnassus Heights campus—scientists will be able to share ideas while staying in compliance with federal guidelines that require separation of federally approved from unapproved stem cell lines. Giving added boost to stem cell research at UCSF, last year the California Institute for Regenerative Medicine—the state agency created with the passage of Proposition 71—disbursed the first in a series of stem cell grants, which had previously been delayed by state litigation. Awarded to UCSF and 15 other California non-profit institutions, the grants support the first year of a three-year program designed to train the next generation of stem cell scientists. “Stem cell biology . . . requires innovative new ways of thinking, new tools, and new skills,” notes Arnold Kriegstein, MD, PhD, director of the UCSF Institute for Regeneration Medicine. “What better way to ensure success than to recruit the brightest and most gifted, and train them for the future.” This spring, a new round of state grants will support research on human embryonic stem cells, including cell lines that are not in the federal registry established by President Bush in 2001. For UCSF investigators, the new grants will constitute an unprecedented boon to research efforts that were previously sustained by private funding alone. The pioneering scientists (right) are among the more than 100 investigators engaged in groundbreaking stem cell research at UCSF. | 10 spring 2007 UCSF Institute for Regeneration Medicine Director Arnold Kriegstein, MD, PhD, is studying the role stem cells play in brain development. Kriegstein and his colleagues have discovered that radial glial cells, found only in the embryonic and fetal brain, play a greater role in brain development than previously thought. These cells, they determined, are in fact the stem cell precursors to the nerve cells that constitute the cerebral cortex. This insight may lead to strategies for growing specific types of nerve cells from embryonic stem cells— a key step on the path to innovative therapies for Parkinson’s disease, epilepsy, ALS, and birth defects. Susan Fisher, PhD, is working to create pure human embryonic stem cell lines. Unlike lines approved by the federal government, which were grown with mouse cells, those developed at UCSF are better suited for treating human disease because they are free from animal cell contamination and genetic mutations. These lines will be the building blocks of the Institute for Regeneration Medicine’s organ regeneration and repair strategy. Robert Blelloch, MD, PhD, is investigating the hypothesis that aberrant stem cells cause and maintain a broad spectrum of cancers. By uncovering the fundamental processes of stem cell differentiation, he hopes to understand how unspecialized cells develop into specific tissues or, when their growth goes awry, into cancerous cells. His efforts could shed further light on the origins of cancer and lead to more effective cancer therapies. MENTORING UCSF Advisory Colleges Provide Support, Advice, Guidance b y Jean Murray M edical school is never easy, but today’s students at the UCSF School of Medicine get a helping hand from a supportive program not available to their predecessors—the Advisory Colleges. Now in its fifth year, the Advisory College Program includes every medical student in all four years of training. It is designed to: n provide mentoring and personalized academic advising n facilitate student communication among peers and faculty n guide students through an array of educational resources, timelines, clinical care settings, and prospective career options The program’s success can be attributed to the compassion and guidance of its eight faculty mentors who, in pairs, lead the four Advisory Colleges, which are a composite of students from each class. For Ellen Hughes, MD ’84, PhD, being an Advisory College mentor is one of the most exciting parts of her work at UCSF. “We have some of the best and brightest and most unique students in the country here at UCSF,” she says. “It’s such a gift to teach them and Advisory College mentors on stage “coating” first-year students at the annual White Coat Ceremony be a mentor to them. Not only are they and enable them to have the best remarkably accomplished, but they possible experience at UCSF. are truly exceptional individuals with a The other six Advisory College wide array of interests and goals.” mentors are Mohammad Diab, MD, To her students and colleagues, Sharad Jain, MD, Carol Miller, MD, Hughes is definitely an exceptional Andrew Murr, MD, Renee Navarro, individual as well. A MD, and John beloved teacher whose Stein, MD. special interests include Representing the integrative medicine, the full spectrum of doctor-patient relationmedical specialties— ship, and spirituality pediatrics, internal in medicine, she is the medicine, psychiatry, director of education at orthopaedics, ENT, UCSF’s Osher Center anesthesiology, for Integrative Medicine emergency medicine— and previously served mentors are available “We have some of the as a co-director of the to advise students Foundations in Patient in all the Colleges on best and brightest and Care course. their future careers. most unique students Hughes started medical Mentors also have in the country here school at UCSF when the honor of “coating” at UCSF. ... It’s such a she was 35, later in life the first-year class than most students. She at the White Coat gift to teach them and was inspired to pursue Ceremony, and follow be a mentor to them.” a medical career by her those students through — Ellen Hughes sister’s dream, which their four years of pictured her walking medical school. And around a hospital in a white coat the close relationship doesn’t stop with a stethoscope around her neck. with graduation; many of Hughes’ “UCSF has been my medical home students keep in touch with personal since the fall of 1979 when I got and professional news as they accepted from the wait list as the begin their careers. oldest student in the Class of 1984,” Since UCSF School of Medicine she reflects. “Later, I somehow classes average 141 students, the convinced the Primary Care Internal mentors’ time is spread thin as they Medicine Residency Program here at balance their commitment to the Parnassus to take me on as a resident Advisory Colleges with teaching and have stayed on as a member of and patient care. Hughes’ “wish list” the faculty in the Division of General includes additional financial support Medicine ever since. I’m incredibly for the program to provide a better grateful that UCSF was willing to take ratio between mentors and students a chance on me.” and to secure the future of the The students in the Hughes-Mack program. Advisory College are glad too. Hughes “One of my greatest joys is being and her co-mentor, Kevin Mack, MD, able to participate in and witness meet with students one-on-one, in the development of students and small groups, and at Advisory College residents as they grow into mature social events. They help students learn physicians,” says Hughes. “I am the ropes, encourage them before honored to be a part of the Advisory exams and second-year boards, and Colleges.” assist third- and fourth-year students For more information or to sponsor an Advisory College, please contact as they ponder specialty decisions. Lyn Oswald, director of Development The mentors advocate for students, and Alumni Relations, UCSF School tell them about opportunities, help of Medicine, at 415/502-8377 or them work through difficult times, [email protected]. | medical alumni magazine 11 ClassNotes Read more class notes online — There are hundreds more class notes online at www.ucsfalumni.org. You can add your own class note and digital photo to keep your classmates updated. If this is your first visit to the site, you will need your community ID number as a temporary password. Your ID is printed next to your name on the address portion of this magazine. 1920s n Carr Bentel, MD ’29, spent his first 30 years after medical school in the medical corps of the United States Navy. He served on the Yangtze River Patrol in the early 1930s and was stationed at Pearl Harbor when the Japanese attacked in 1941. Bentel survived the war and returned home to take posts as a radiologist and, later, as executive and commanding officer of naval hospitals around the United States and in the Canal Zone. In 1959 he retired from the military and became the director of medical and surgical services for the California State Mental Hospitals, a post he retired from in 1973 to care for his ailing wife. He still lives on his own in San Francisco, close to his son and daughter-in-law, and walks two miles a day around his neighborhood. 1940s n George S. Hannah, MD ’47, (pictured below with his wife) retired in 1993 after practicing pediatrics, mostly (40 years) in San Leandro. He enjoyed the Bay Area and frequent trips to the Sierra. After graduating he spent two years in the Navy (having benefited from its V-12 program), mostly at Bremerton Naval Hospital near Seattle. He is married and has two daughters, both in Colorado. He’s living in a small town, Niwot, near Boulder and Estes Park. He enjoys | 12 spring 2007 the outdoors, hikes (now reduced to snow-shoeing in the winter), traveling, and photography. In 1997, his daughters arranged a 50th anniversary party for him and his wife at the Alumni House on the Berkeley campus—very nice. n Jack J. Williams, MD ’47, has been fully retired for 22 years. He enjoyed frequent overseas travel, until his wife died in 2001, with an emphasis on good snorkeling areas (e.g., Australia, Maui, Aruba, Aqaba). In 1986, he and his wife went on their own to Tanzania and Kenya with local guides. He made a videotape of African animals which, when edited down to about 90 minutes, is every bit as good as anything National Geographic has produced (in his opinion). His children’s careers: one school teacher, one computer nut, one lawyer, and one successful businessman. He also has four grandchildren and four greatgrandchildren. One great-grandchild, age 17, is academically gifted and interested in science and medicine. 1950s n Ron Lever, MD ’56, has been happily retired since July 4, 1993, though he is now busier than ever. He is taking writing classes and working on a second book, an autobiography. He has just been elected president of the Men’s Club at Valley Beth Shalom Synagogue in Encino, where he and his wife, Doreen, reside. They have been members since their son’s bar mitzvah in 1972. He and Doreen have been married since 1952. They celebrated their golden 50th wedding anniversary in 2002 with a gala dinner dance along with 175 close friends and family. They have a daughter, Karen, and son, Rick, and four grandchildren: Rubin, Shifra, Jeremie, and Ilana. n Melvin L. Rubin, MD ’57, retired from his position as professor and from active clinical practice in 1997, though he maintains a daily educational role on the (volunteer) faculty at the University of Florida College of Medicine. Committed to ophthalmic education in its broadest sense, aside from giving lectures and courses, he developed a national examination program—the Ophthalmic Knowledge Assessment Program— now in its 39th year. He’s been invited as visiting professor on over 60 occasions, delivered 20 named lectureships, and has written over 100 publications and seven textbooks, one of which won an AMMY as the best medical book of the year (from the American Medical Writers Association). In addition to his academic pursuits, he has served on the board of trustees and as president of the American Academy of Ophthalmology, as president of the AAO Foundation, on the board and as chairman of the American Board of Ophthalmology, as trustee and president of the Association for Research in Vision and Ophthalmology, and as chairman of the Council of the American Ophthalmological Society. He and his wife, Lorna, celebrated their 53rd anniversary last June. They have three children and five grandchildren who reside with their respective families in Toronto, Canada; Santa Fe, New Mexico; and Santa Cruz, California. n Don Adler, MD ’57, retired in August 2006 from a private practice specializing in reproductive medicine. In addition to private practice, he was chairman of Ob/Gyn & Residency training at CedarSinai Hospital, and was on the board of the Pacific Coast Fertility Society. In his spare time, he serves on the board of the Los Angeles Children’s Museum, has been sculpting stone for eight years, plays tennis and bridge, and spends a great deal of time traveling with his wife of 53 years, Barbara (pictured above). They have visited all seven continents. They have three sons, all doctors, and five grandchildren. n James Hamill, MD ’57, retired from a plastic surgery practice in Sacramento in 1992. Since that time, he’s kept busy with home and garden maintenance and restoration (just his) and has learned to develop a thriving correspondence via email. He also spent 12 of those retirement years going to Japanese language school and has many pen-pals in that language. Now he’s hooked on Netflix. He’s also traveled to 96 countries, many of them more than once, with his wife, Joan Petesch (pictured below), who he met during their senior year while she was working as a PM float nurse at Moffitt Hospital. They have four children: Elaine, 48; Nicholas, 45; Leo, 44; and Valerie, 40. Their children, in turn, have provided them with 11 grandchildren. 1960s n Robert Darrell Cardiff, MD ’62, was the UC Davis School of Medicine chair of Pathology and founding director of Medical Informatics. He was the instructor of record of the Pathology curriculum for 17 years. His teaching was recognized by multiple awards. He is currently at UCD Center of Comparative Medicine acting as an international consultant, where his unique niche in science is mouse tumor pathology. Last year he was elected an AAAS Fellow and promoted to distinguished professor. He recently finished a tour as the president of the International Association for Breast Cancer Research. He continues to play full court basketball three mornings a week and has been training for 10K races. His times are getting below nine-min/mile. He intends to be the last man standing. He and his wife, Sally, have been married 44 years and have three children and three grandchildren. Their children have taken diverse paths to become archaeologists (Darrell), lawyers (Todd), and rock musicians (Shelley). They are delighted and doting grandparents. Life is good. n Laurence S. Reisner, MD ’67, has enjoyed a wonderful career in academic anesthesiology at UCSD Medical Center and retired from practice in July 2002. He was chief of OB Anesthesia for several years and eventually the acting chair of his department for two-and-a-half years. He still teaches two days a month. He and his wife, Susan, have two grown children: a daughter with two lovely children, and a son who is an attorney. Since retiring he has kept quite busy by joining the Sheriff’s Volunteer Patrol and is currently the administrator of that unit for his local substation. n Douglas Frederick Schwilk, MD ’67, fully retired from his dermatology practice with Kaiser-Sacramento in October 2006. However, he semi-retired in June 2002, working only six days per month these past four years, which was perfect. Dermatology was a lot of fun, involving both a medical differential diagnosis and surgery. On a personal note, he has been continued on next page You Don’t Have to Be Wealthy To Make a Difference in This World You can make this a healthier and happier world for future generations by supporting the medical research and teaching programs of the University of California, San Francisco By means of a Charitable Gift Annuity with the University of California, San Francisco Foundation you can: Increase your income Receive a charitable deduction Avoid capital gains tax, and Provide valuable support for the research and teaching programs of UCSF. Sample Rates If You Are You Can Earn 65 6.0% 70 6.5% 75 7.1% 80 8.0% The Planned Giving Program University of California, San Francisco 85 9.5% 44 Montgomery Street, Suite 2200 90 11.3% San Francisco, CA 94104-4709 Tel: 415/476-1475 Email: [email protected] To learn more about the UCSF Foundation Charitable Gift Annuity Program or other charitable life income opportunities, please contact: U niversity of C alifornia , S an “The greatest thing this generation can do is lay a few stepping stones for the next generation.” — Charles F. Kettering F rancisco | medical alumni magazine 13 Class Notes 1960s | continued In Memoriam Mervin J. Goldman, MD ’38 Ellen Brown, MD ’39 John B. Castiglione, MD ’42 Prescott W. Thompson, MD ’42 Howard J. Weinberger, MD ’42 Edmund D. Jung, MD ’44 Victor P. Bond, MD ’45 Walter S. Mazen, MD ’45 James L. Caffee, MD ’46 Robert E. Clark, MD ’46 Harry K. Darling, MD ’46 Reynold F. Brown, MD ’47 Thurid B. Lininger, MD ’48 Charles D. Noonan, MD ’53 Raymond W. Rakow, MD ’53 Bernard S. Sorkin, MD ’53 Melvyn H. Krause, MD ’57 Marvin Weiner, MD ’57 Marvin A. Brownstein, MD ’58 Mikel Duino, MD ’60 Frank A. Elliott, MD ’62 James S. Lieberman, MD ’63 Richard C. Rentz, MD ’68 Duane A. Olson, MD ’72 Douglas Beers, MD ’77 Ruben E. Montes, MD ’00 faculty, housestaff Edwin P. Brennan James S. Browne Leon Cohen Madeleine Butt Grumbach Robert D. Hindi Herbert S. Kaufman Evelyn Y. Lee Robert I. Mahon Robert A. Major John P. Mc Cann Selby Mohr Sally E. Perlman Yung J. Sohn William J. Wedemeyer, Jr. Roger W. Westmont Brian R. Young Masanori Yukimoto | 14 spring 2007 married to Joanna for 40 years (pictured below). His daughter is a third-year internal medicine resident at UC Davis and his son is in academia— PhD from Stanford in evolutionary biology-botany—a little too complex for dad. His interests include vintage ballroom dancing, along with folk dancing (two nights plus per week). He loves to hike, bird watch, and travel, plus he has been diligently studying Italian for the past three years. His favorite sites for foreign travel include South Africa, Italy, and Sweden. 1970s n Peter S. Moskowitz, MD ’70, is a clinical professor of radiology at Stanford University School of Medicine and staff radiologist at Lucille Packard Children’s Hospital at Stanford. Prior to teaching at Stanford, he was in private practice for 18 years. Currently, he is the founder and director of the Center for Professional and Personal Renewal in Palo Alto, a center devoted to helping physicians overcome career burnout and creating a positive work-life balance. He has become an expert in the field of physician wellness and career renewal and has spent the past nine years lecturing to physicians around the country on these topics. n K. Rose, MD ’72, found a career in a semi-rural family practice via a medical school externship in the emergency department of Community Hospital in Santa Rosa. In 1998, he recruited a young associate to take over the majority of his office responsibilities while he concentrated on surgery assisting. One week after his arrival, Columbia-HCA threatened to close their Healdsburg Hospital. Thus began a five-year odyssey to form a non-profit corporation, recruit a management team, sell municipal bonds, raise half-a-million dollars in donations, and buy the hospital. Included in the rescue effort was the construction of a new Alliance Medical Center, the descendent of the original free clinic that led him to Healdsburg 32 years earlier. The high point of his research activity was the invention of transdermal nicotine (Habitrol) with his brother, Jed, at UCLA. At home, house construction has been the recurring theme of the past three decades. A quarter-acre vegetable garden and orchard provide food, exercise, and gentle reminders about the cycle of life. He and his wife, Cathryn, have been married for 30 wonderful years. After raising five bright and energetic offspring, they enjoy the empty nest with quiet time together. They adore the mates their children have brought into their lives. Their three grandsons will soon be joined by a granddaughter. n Barrie Von Smith, MD ’72, was active duty in the Army as a physician from 1972-1977. He took his Family Practice boards in 1976. After Army life he moved to Emmett, Idaho, a rural community in the southwest part of the state. He enjoyed solo practice until 2005. He rejoined the Army Reserves in 1997 and has enjoyed humanitarian missions and recent deployment. Medicine has been extremely satisfying and rewarding for him. He is happily married to his wife of 38 years (pictured below). They have seven beautiful daughters, all of whom have finished college. They now have 11 grandchildren and travel the country visiting them. They continue to live on a large farm in southwestern Idaho. The kids don’t want them to ever sell the clinic in town or the homestead where they grew up—and they probably never will. Life is good, and they have been blessed. n Colin Raitiere, MD ’77, left a fulltime practice and is now working two days a week. He got certified in clinical lipidology and lives off the beaten path in a little house on a hillside surrounded by rugged knob land, rattlesnakes, copperheads, and black widows. He has a little studio and makes lots of music. He is taking mandolin lessons and CD #4 is coming out in three weeks. He was divorced, and then married the love of his life. His son, Aaron, is in an MFA program in recording arts in Nashville, and daughter, Kate, is a middle school language arts teacher in Lexington, Kentucky. n Paul F. White, MD ’77, is finishing up a career in clinical research (400+ peerreviewed publications are enough!). He plans to spend more time furthering the goals of his not-forprofit foundation, the White Mountain Institute. The foundation has applied for CME accreditation and supports the arts and alternative medical practices. As a huge Cal Bear fan, he keeps busy traveling between Dallas and the Bay Area. Although he still spends too much time in airplanes, he has managed to find more time to enjoy outdoor activities (e.g., climbing mountains in New Zealand, Indonesia, and Northern Italy). He and his wife, Linda, also enjoy going on cruise ships. They are completely renovating their “old” house in Los Altos in preparation for an “early retirement.” Linda is involved in a variety of community-related projects and their two lovely daughters, Kristina and Lisa, have both found “significant others.” Kristina is in marketing for a computer software company in Sunnyvale and Lisa is a research analyst in Washington, D.C. 1980s n Kathleen Hirtz, MD ’82, is still in practice in Springfield, Oregon. She has a general practice and specializes in sports medicine and bariatrics. She began flying in 2001 and started performing air shows in her Pitts professionally in 2003. She and Tom were divorced in 2002, but continue to be good friends and see each other often. She married Steve Wolf, her aerobatic instructor, in 2003. She was diversion from clinical work. She spends a lot of time staying fit for hiking and skiing in Utah, where her family tries to spend as much time as possible. She also dances several times per week (Israeli and Ballroom). She continues to follow her husband, Bruce, up mountains, down ski slopes, and on the dance floor. His vitality and curiosity are an inspiration. They have three children: Sam, Hannah, and Max. n Ludmila Bojman, MD ’82, followed flying an aerobatic glider (pictured above) until she had an off-field landing in 2004 and crashed. She broke her back, requiring extensive surgery. She has continued to perform air shows in the Northwest. She continues to be very active in skiing, rollerblading, ice skating, biking, and kayaking. She and Steve have begun traveling, which she enjoys very much. n Ryk Graf Tanalski, MD ’82, continues to work at Kaiser Vallejo Anesthesiology. He’s happy to report that the whole family is doing great despite minor complications: sequestered disc, medulloblastoma, and teenage angst. The complications have all been resolved, except for the teenage angst. He’s still recreating as time allows, with some changes: more road than mountain biking (less maintenance), skiing again for the first time in 15 years (poor snow conditions), and still ready to go snowboarding if they ever get some powder! n Diane R. Krieger, MD ’82, continues to practice endocrinology and clinical nutrition on her own, enjoying the independence and tolerating the pressures. For many years she was the only boardcertified female endocrinologist in Miami Dade County, and this afforded her the great luxury of choosing her own pace and practice style. For the last six years she has been in a partnership conducting research on nutritional products for supplement companies, a very interesting her husband to Los Angeles after she finished her radiology residency and neuroradiology fellowship in Seattle. For many years, she worked as a staff radiologist at a few local hospitals. In 1999, she switched to doing breast imaging. She is now medical director of Beverly Tower Women’s Center located in Beverly Hills. After turning 50, she decided to get some exercise and began running with a local running club. She just completed her 15th marathon and qualified for the 2007 Boston Marathon. She has been married to Daniel Cohn since 1982. They have three children: Zachary, 20, and 18-yearold twin girls, Rachel and Marissa. n Barbara Natterson-Horowitz, MD ’87, is about to hit the 20-year mark at UCLA. Her specialty within cardiology is echo; she serves as the director of interventional echocardiography and the director of imaging for the UCLA Cardiac Arrhythmia Center. This year she developed a novel procedure that she named PICE (percutaneous intrapericardial intracardiac echo), which is used for complex ablation procedures. A lifelong animal lover, she now provides the cardiovascular care to the primates at the Los Angeles Zoo. She and her husband, Zach, have two children (pictured below). continued on next page | medical alumni magazine 15 Class Notes | continued 1990s n Tracey Ann Banks, MD ’92, founded an Ob/Gyn practice in McKinney, Texas (a suburb of Dallas) seven years ago, which has now grown to six providers. She has three wonderful children: an 11-year-old girl, Gabrielle, and two boys, Sean, 8, and Ayden, 4. Her husband, Mark, works for a logistics firm. They are just enjoying life and cherishing every moment. n Laurence Peiperl, MD ’92, after several years in HIV vaccine research and directing the UCSF Center for HIV Information, has recently moved to the Public Library of Science as an editor for the open-access journal PLoS Medicine. He also volunteers at the Haight Ashbury Medical Clinic. He and Chuck are still together, going on 18 years. He hopes to see many of his classmates at the reunion in May. n Chris Price, MD ’94, is currently in private practice in Sacramento. He is doing family practice out of his office, along with occasional visits to a couple of nursing homes, and he admits to one of three different hospitals. He is married and has one child (age 3 1⁄2). Life is really pretty good. n Mason Lee, MD ’98, has been prac- ticing full scope oral/maxillofacial surgery in Marin County for the last four years. He is currently on staff at Marin General Hospital and Novato Community Hospital. He’s been challenged each day by the hectic demands of running a private practice and keeping a normal family life. His three kids (Josh, Erin, and Nicole) keep him pretty busy. Being a classroom dad, swim teacher, and play buddy are his reality. recent grads Gil Kryger, MD ’01, is in his last year of residency in plastic surgery at Stanford. He will soon attend the University of Southern California for a fellowship in hand and microsurgery. He and his brother will graduate at the same time and they intend to open a practice together in Los Angeles. He has a beautiful baby girl named Mika, who is less than a year old and super-cute. He still surfs and runs and loves to hang out with his wife, Ella. Bryan Huang, MD ’03, completed his residency at Stanford and is now practicing internal medicine as an assistant clinical professor at UC San Diego, Division of Hospital Medicine. Now that he has moved to San Diego, he is trying his hand at surfing and volleyball. > > > Send us your class notes — online at www.ucsfalumni.org or use the envelope in the center of this issue. StayConnected with Alumni Email WEB-BASED EMAIL > Show your UCSF pride > [email protected] > Sign up now so you can have the email address you’ve always wanted. > Use the forwarding service so fellow alumni and friends will never lose track of you. 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