Curriculum Vitae
Dina Ahmed Mehaney Osman, MD
19 El-Ghith st.- Agouza- Giza- Egypt
Giza,12311
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E-mail:[email protected];[email protected]
Education
2010
MD of Clinical and Chemical Pathology – Faculty of Medicine – Cairo University.
2006
Master of Clinical and Chemical Pathology (Very good grade) – Faculty of Medicine
– Cairo University.
2001
M.B., B.Ch (Excellent with honor grade) -Faculty of Medicine – Cairo University.
Appointments
2010
Lecturer of Clinical and Chemical Pathology –Faculty of Medicine -Cairo University.
2006 – 2009
Assistant Lecturer of Clinical and Chemical Pathology –Faculty of Medicine -Cairo University.
2003 – 2006
Resident of Clinical and Chemical Pathology – Cairo University Hospitals.
2002 – 2003
House Officer – Cairo University Hospitals.
Other Positions and Employment
2006-2009 Member of the Chemical Pathology lab team – Biochemical Genetic Metabolic Unit
Laboratory (BGMUL)-Centre of Social and Preventive Medicine (CSPM)-Cairo University .
Main responsibilities :
-Running of Mass Spectrometry for screening of Inborn Errors of Metabolism (IEM ) through a
project titled (Program for Prevention, Early Detection and Early Intervention in Egyptian Children
with Genetic Disabilities and Children at risk) (EuropeAid/122327/D/G/EG) .
-Writing of monthly ,Quarterly and Interim reports about the project.
-2012 till now: Member of Cairo University technical support office for projects and grants
(TSOPG).
Research and Training
2005
Thesis study submitted for the fulfillment of the Master degree under the title of “Role of
Glutathione- S-Transferase in colorectal cancer”.
2006-2007
Training on molecular biology techniques (Sequencing ,PCR, RFLP,DHPLC) as a practical part of
MD thesis titled (Molecular diagnosis of nuclear and mitochondrial DNA mutations among Egyptian
children with Mitochondrial Encephalomyopathies).
Location : the molecular biology lab of Bambino Gesu Research hospital ,Rome ,Italy.
2009
Thesis study submitted for the fulfillment of the MD under the title of “Molecular diagnosis of
nuclear and mitochondrial DNA mutations among Egyptian children with Mitochondrial
Encephalomyopathies".
2010
Elucidation of the molecular pathogenesis of mitochondrial disorders among Egyptian children. Cairo
University funded project.
2011
Master Course Advanced qPCR Techniques for Publication Success: Following MIQE
Recommendation .European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. 2011.
Proceedings of International Conferences:
- Dina A. Mehaney ,Fayza A.Hassan,Laila A.Selim,Sawsn A. Hassan,Enrico Bertini,Fillipo
Santorelli ,Fabiana Fattori,Randa Sabry ,Reham Zeyada .Biochemical and genetic analysis of Leigh
syndrome with complex I deficiency.The United Mitochondrial Disease Foundation(UMDF )
Scientific meeting: Mitochondrial Medicine 2010.poster presentation and abstract.
-Mehaney D., Hassan F., Sabry R.,Zeyada R., Mohie A.,Selim L.,Abdelhady S., Verrigni D.,
Bertini E., Santorelli F., Fattori F., Carrozo R. Mitochondrial Myopathy Of Childhood Associated
With Mitochondrial DNA Depletion .3rd Pan Arab Human Genetics Conference
March 2010,Dubai, United Arab Emirates.
European Society of Human Genetics (ESHG)
Conference . Gothenburg ,Sweden. June, 2010 .Poster presentation and abstract.
Dina Mehaney ,Fayza Hassan ,Laila Selim,Sawsn Hassan ,Enrico Bertini,Fillipo Santorelli,Fabiana
Fattori,Randa Sabry,Reham Zeyada. molecular genetic analysis of the mitochondrial ATP Synthase
6 gene in Egyptian children with neuropathy, ataxia, retinitis pigmentosa / maternally inherited
leigh’s syndromes. Human Genome Meeting 2011, Dubai, United Arab Emirates. Poster
presentation and abstract.
Dina Mehaney ,Fayza Hassan ,Laila Selim,Sawsn Hassan ,Enrico Bertini,Fillipo Santorelli,Fabiana
Fattori,Randa Sabry,Reham Zeyada .Biochemical And Molecular Diagnostic Features Of Mitochondrial And
Nuclear DNA Mutations Among Egyptian Children With Mitochondrial Encephalomyopathies. AACC annual meeting
2011 . Abstract.
Proceedings of National Conferences:
- Dina Mehaney :Mitochondrial myopathy of childhood associated with mitochondrial DNA
depletion .Molecular Biology :into the future ,ClinChem Conference :The 1st Annual Scientific
conference of the Clinical and Chemical Pathology department-Faculty of Medicine –Cairo
University),April 2010.Speaker and abstract.
- Dina A. Mehaney ,Fayza A.Hassan,Laila A.Selim,Sawsn A. Hassan,Enrico Bertini,Fillipo
Santorelli ,Fabiana Fattori,Randa Sabry ,Reham Zeyada .Biochemical and genetic analysis of Leigh
syndrome with complex I deficiency. BioVisionAlexandria Conference. April 2010.poster
presentation and abstract.
- Dina Mehaney :Mitochondrial DNA depletion syndromes . Diagnosis of mitochondrial and
encephalomyopathies in Egyptian Children ( Focus group ).The XI world conference of ICNC
(International Child Neurology Congress) ,May 2010. Speaker
Curriculum Vitae of Dr. Dina Ahmed Mehaney Osman
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SCIENTIFIC MEMBERSHIP ,
COMMITTEES
Member of the Egyptian Society of Laboratory Medicine (ESLM) .
Member of Arab society of Medical Research (ASMR).
Awards
Best MD thesis award for the academic years 2009-2010, Cairo University.
Activities
Department Local activities
(Mitochondrial disorders :clinical ,genetic and diagnostic features ) at the Chemical Pathology
department –Faculty of Medicine -Cairo University . Oral Presentation.2006
(Identity Assessment ) at the Chemical Pathology department ––Faculty of Medicine -Cairo
University . Oral Presentation. 2008
Seminars ,Workshops and conferences:
Millipore Bioscience seminar (Millipore Life Science Research Application Solutions ).2007
20th Annual Conference of Pediatric Department -Cairo University .2008. Attendant
Biotechnology for Better Life Conference –National Research Centre .2009. Attendant
20th Annual Conference of the Egyptian society of Laboratory medicine.2009. Attendant
Advanced and user friendly DNA,RNA and Protein analysis ,the CLC bio way Workshop .2009. Attendant
Euro-Mediterranean Innovation Marketplace.2010. Attendant
21th Annual Conference of the Egyptian society of Laboratory medicine.2010 .Attendant
rd
The 3 Pan Arab Genomics meeting.Dubai,United Arab of Emirates.2010. Attendant
The Annual Meeting of the American Association of Clinical Chemistry .CA,USA.2010. Attendant
Course in mitochondrial metabolism and Cancer. European Genetics Foundation (EGF) ,Bologna,Italy.2010
22th Annual Conference of the Egyptian society of Laboratory medicine.2011. Attendant
Training course for Screening Inherited Metabolic Disorders By Tandem Mass spectrometry
(MS/MS) Egypt ,Faculty of Medicine ,and Cairo University. 2011.Organizer and trainer.
M.Sc. and MD Supervisions
-Validation of triple marker medians used in antenatal screening of Egyptian females.(M.Sc. thesis
)
-The effect of Aerobic and Anaerobic Oxidative stress following acute exercise on The lipid
peroxidation biomarkers in Egyptian athletes . (M.Sc. thesis )
-Serum Sclerostin Level Among Egyptian Rheumatoid Arthrits Patients: Relation to Bone mass,
Disease Activity and Radiological Grading. (MD thesis )
-The potential Role of Placental Protein-13 as a First Trimester Screening Marker for
Preeclampsia in Egyption pregnant females. (M.Sc. thesis )
Publications
Preliminary results of Egypt's experience for use of Tandem Mass Spectrometry for
expanded metabolic screening .Fayza Hassan, Fatma Elmougy ,Iman Madour ,Sawsn
Abdelhady,Laila Selim ,Sahar Abdel Atty ,Marian Morgan,Fadia Salem ,Azza Orabi ,Dina
Mehaney ,Mohamed Abdel m onem,Ibrahim El Nekhely, Nadia Moharram. Journal of Applied
Sciences Research, 2009, 5(10): 1425-1435.
Screening for Organic Acid Disorders among Egyptian Children with Clinically Suspected
Neurometabolic Disorders. Laila Abdel Moteleb Selim , Sawsan Abdel Hadi Hassan , Fadia Ali
salem , Fayza Abdel Hamid Hassan , Fatma El Mogy , Sahar Abdel Atty , Iman Mandour , Marian
Fathy , Azza El Orabi amin , Iman gamal el din , Manal sadek El defrawy , Ali elayat , Amira El
Badawy , Marian yousry , Mohammed Abdel Monem , Dina Mehaney .Research Journal of
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Medicine and Medical Sciences, 2009,4(2): 369-385.
Sweat conductivity and chloride titration for diagnosis of cystic fibrosis in high risk egyptian
children. El-Falaki M, Hamdi H,Mohsen M, Shahin W, Hosny H and Mehaney D .The Egyptian
Journal of Chest and Tuberclosis .2011;60(1):1-10.
Dina A. Mehaney, Fayza A. Hassan, Laila A. Selim, Sawsn A. Hassan, Enrico Bertini, Fillipo
Santorelli, Fabiana Fattori, Randa Sabry, Reham Zeyada, 2011, Biochemical and genetic
analysis of Leigh syndrome with complex I deficiency,mitochondrion,650-651.
Dina El Gayar, Marwa Sheta, Dina Mehaney, and Eman Halawa.Detection of Inborn Errors of
Metabolism among Critically Ill Egyptian Children Using Tandem Mass Spectrometry. The
Egyptian Journal of Laboratory Medicine, 2012, 11, 66-69.
Laila Selim, Dina Mehaney, Fayza Hassan, Randa Sabry, Reham Zeyada, Sawsan Hassan,
Iman Gamal Eldin, Enrico Bertini. Mitochondrial DNA depletion syndrome presenting with
ataxia and external ophthalmoplegia: Case report. Egyptian Journal of Medical Human
Genetics.2012, 13(3), 351-357.
Noha Elhusseini,Dina Mehaney. New Insights on Iron Study in Myelodysplasia.The Turkish
Journal of Hematology. In press.
Selim, Dina, Fayza, Sawsan Abdel Hady Hassan, Iman Gamaleldin, Randa Sabry,Enrico
Bertini.Merosin deficient congenital muscular dystrophy: Clinical, neuroimaging and
immunohistochemical study of 8 Egyptian pediatric patients . Journal of Genetic Engineering and
Biotechnology.2013, 11(1) 61–68.
Noussa El Basha, Mona Mohsen, Marwa Kamal , Dina Mehaney .Association of vitamin D
deficiency with severe pneumonia in hospitalized children under 5 years Comparative Clinical
Pathology.2013,22(3)
Laila Selim , Dina Mehaney.Mitochondrial encephalopathy with lactic acidosis and stroke-like
episodes in a Japanese child: Clinical, radiological and molecular genetic analysis. The Egyptian
Journal of Medical Human Genetics,2013 14(3),317–322.
Mona M. El-Falaki, Walaa A. Shahin , Noussa R. El-Basha , Aliaa A. Ali ,Dina A. Mehaney ,
Mona M. El-Attar.Profile of cystic fibrosis in a single referral center in Egypt. profile of cystic
fibrosis in a single referral center in Egypt, J Adv Res (2013)
D Mehaney, F Hassan, L Selim, M Abdelmonem, D Gayar, M Sheta, E Halawa, I Gamal
Eldin, A Kaddah, R Elkaffas, N Elkady . The prevalence of inborn errors of metabolism among
Egyptian pediatric patients admitted to the intensive care unit using tandem mass spectrometry. J
Inherit Metab Dis (2013) 36 (Suppl 2):S55–S90
L Selim, R Vancoster, SA Hassan, A Vanlanderb, J Smet, E De Latterb, K
Vandemeulebroeckeb,DMehaney,DAbdo,GA Nakhla,M Mostafa, D Habetse, J Bakkere, A
Abdel Barry. Mitochondrial neurogastrointestinal encephalopathy: clinical, biochemical and
molecular genetic study in three egyptian patients. J Inherit Metab Dis (2013) 36 (Suppl 2):S55–
S90
D Mehaney, L Selim, M Shaarawy.Molecular screening and diagnosis of mitochondrial
diseases: a two year study. J Inherit Metab Dis (2013) 36 (Suppl 2):S55–S90
L Selim, S Abdelhady, F Salem, F Hassan, F El Mogy, S Abdel Atty, D Mehaney, I
Mandour,M Abdelmonem, M Fathy, A Orabi, I Gamal Eldin, A El Ayat, A El Badawy, M
Yousry.The Screening of high risk Egyptian children with suspected inborn errors of metabolism
using tandem mass spectrometry: a 5 year report. J Inherit Metab Dis (2013) 36 (Suppl 2):S55–S90
Curriculum Vitae of Dr. Dina Ahmed Mehaney Osman
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Project management skills
-Main investigator in Science and Technology funded project titled :The Egyptian Pediatric
Cardiology Center of Excellence (starting ,May 2013) aiming to install the next generation
sequencing technology for elucidation of the genetic causes of pediatric cardiomyopathies.
-Young Researcher at European Union Funded project(EuropeAid/122327/D/G/EG) titled :
Program for Prevention, Early Detection and Early Intervention in Egyptian Children with Genetic
Disabilities and Children at risk (2006-2008 ).
-Principle investigator of Cairo university -Faculty of medicine research projects:
1)Elucidation of the molecular pathogenesis of mitochondrial disorders among Egyptian
Children(2010 till now ).
2)Evaluation of the Medians for the biochemical and ultrasound markers in Egyptian
Females undergoing first-trimester screening for trisomy 21 (2011 till now).
-CO-Principle investigator of Cairo university -Faculty of medicine research projects:
1)Impact of CYP3A4 and CYP3A5 gene polymorphisms on dose requirement of calcineurin
inhibitors; Cyclosporine and Tacrolimus, in Egyptian renal allograft recipients. (2010 till now ).
2)Assessment of Mitochondrial DNA Copy Number and Cognitive Function in Apparently Healthy
Elderly Egyptians (2010 till now ).
3)Evaluation of the Serum Hepcidin analysis in Egyptian patients with Myelodysplasia
(2010 till now ).
4) The frequency of CFTR gene mutations among high risk Egyptian pediatric patients with
Cystic Fibrosis (2011 till now).
Skills and Qualifications
-Bioinformatics diploma .Sira Corporation ,Egypt .2009
-Computer skills :
YAT professional Diploma (Microsoft Office and Internet). 2006
-Languages
Arabic :mother tongue, English : fluent both spoken and written (TOEFL®
ITP
),French : Fair
References
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Professor. Dr. Fayza Abdelhamid Hassan :Prof of Clinical &Chemical pathology Faculty of Medicine –Cairo University
Professor. Dr. Fatma elmougy :Head of Clinical &Chemical pathology department Faculty of Medicine –Cairo University
Prof. Dr. Laila Abdel Moteleb Selim: Professor of pediatrics and pediatric neurology
and inherited metabolic diseases , Cairo university children hospital
Prof. Dr. Sawsan Abdel Hady Hassan :Professor of pediatrics and Genetics,Head of
genetic department--Faculty of Medicine –Cairo University
Prof. Dr. Fadia Ali Salem: Professor of pediatrics and Genetics--Faculty of Medicine –
Cairo University
Prof. Dr. Azza El Orabi amin :Professor of pediatrics, pediatric neurology and inherited
metabolic Diseases, , Cairo university children hospital
Professor Dr Rashika Elridi :Professor of Immunology, Zoology Department, Faculty
of Science, Cairo University, Tenure position.
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