Issue Six Spring 2009 8 Current Clinical Trials The Urology Center TUCC is now enrolling patients in the following clinical trials: spread from the kidney to another part of the body. Over-active Bladder We are currently enrolling male and female patients in a clinical trial for the treatment of over-active bladder. If you have been diagnosed with over-active bladder or have experienced symptoms such as urinary frequency, urgency or urge incontinence, you may qualify for this study. Benign Prostatic Hyperplasia (BPH) We are currently enrolling patients in a clinical trial for the treatment of an enlarging prostate. Bladder Cancer We are currently enrolling bladder cancer patients in a study for those who are newly diagnosed or experiencing recurrent low-grade tumors. Kidney Cancer Newly diagnosed kidney cancer patients interested in enrolling in this trial must have undergone a nephrectomy or be scheduled to have the procedure. Lesions (cancer cells) must have Phase I Vaccine Study Requirements for enrollment: • Diagnosed with prostate cancer • Must have undergone treatment for the disease • PSA must be rising OR The Urology Center of Colorado 2777 Mile High Stadium Circle Denver, CO 80211 • Diagnosed with renal cell or bladder cancer • Can be Stage II, III or IV • Cancer must not have metastasized to distant areas of the body Prostate Cancer We are currently enrolling prostate cancer patients in a study for men on hormonal therapy. Requirements for enrollment: • PSA must be rising • Cancer must not have spread to the bones For all study participants: of Colorado IN FOCUS Study medication and procedures are provided at no cost. Participation in all studies is voluntary. For more information about clinical trials at TUCC, please speak with your physician or visit www.tucc.com. Condition Spotlight Prostatitis Craig Sakurada, M.D. The prostate is a walnut sized gland located at the base of the bladder. Its main function as a secondary sex gland is to produce fluid and nutrients that allow sperm to live outside the body. Unfortunately, once fertility is no longer an issue for men, the gland often causes more problems than benefits. One very common problem affecting men of all ages is prostatitis. According to some estimates, men have a 5 -10 percent chance of being diagnosed with some form of prostatitis during their lifetime. According to the American Academy of Family Physicians, nearly 25 percent of physician visits for genitourinary complaints can be attributed to prostatitis. Prostatitis accounts for nearly two million outpatient medical visits per year, costing more than 6 billion dollars annually. Autopsy studies have revealed an even higher prevalence of prostatitis in men 64- 86 percent. Why are so many men suffering from prostatitis? The answer, unfortunately, is not so clear cut. For all of the great advancements in medicine, prostatitis is still a poorly understood disease. This is what we do know. Prostatitis is, by definition, inflammation of the prostate gland. What causes the inflammation, however, is the million dollar question. The National Institutes of Health classifies prostatitis into four categories: 1. Acute bacterial prostatitis: These patients tend to be very sick with high fevers. They experience burning with urination, extremely tender prostates on examination and significant voiding dysfunction. 2. Chronic bacterial prostatitis and 3. Chronic non-bacterial prostatitis / prostatodynia / chronic pelvic pain syndrome: These patients tend to have more chronic, low grade and often intermittent symptoms. The symptoms can range from intermittent, low grade burning with urination, urinary frequency, urgency and slow urinary stream to pelvic/ testicular/groin/low back pain. Patients may also experience burning, pain and even blood with or after ejaculation as well as sexual dysfunction (premature ejaculation, erectile dysfunction). Patients may often feel tired, lethargic, run down and run low grade intermittent fevers and chills (with bacterial prostatitis). 4. Asymptomatic inflammatory prostatitis: Typically, these patients do not complain of pain or exhibit symptoms. While these disease categories do exist, ‘pigeon-holing’ patients into one or another can be detrimental and shortsighted. The most challenging groups to treat are the chronic bacterial and chronic non-bacterial prostatitis patients. The vast majority of these patients are classified into the chronic non-bacterial prostatitis category. It is very difficult to identify and isolate a treatable bacteria in many, if not most, patients who present with prostatitis symptoms. However, a significant portion of these patients do respond favorably to antibiotics, which raises concerns about such defined labels. Some medical professionals believe that this is all a spectrum of the same disease, just with varying degrees of clinical symptoms and bacterial detectability. Others feel that there are truly non-infectious disease causes for prostatitis. One interesting theory currently under investigation is that some forms of prostatitis may be classified as autoimmune disorders, in which the body fails to recognize normal prostate tissue and mistakenly attacks it causing inflammation. Similar autoimmune disorders already exist within the body such as rheumatoid arthritis. Others theorize that the reflux of urine into the prostate ducts, stress, pelvic floor dysfunction, infrequent ejaculation or various foods and beverages may contribute to prostatitis. IN FOCUS 2 Patient Survivorship (continued) Condition Spotlight (continued) Regardless of the cause, the different classifications of prostatitis are often treated in a similar fashion. The mainstay of treatment is antibiotics. Patients may be prescribed a minimum of 6-12 weeks of antibiotics to adequately treat prostatitis. Other treatments such as alpha-blockers (Flomax, Uroxatrol, Cardura, etc.), anti-inflammatories (ibuprofen, NSAIDS), quercetin/ bromelain, zinc, Osteo-Biflex, prostate massages and dietary modifications all may be used depending on the clinical situation. Encouraging increased fluid intake, voiding and ejaculation may all prove to be beneficial as well. Novel treatment approaches such as cooled thermotherapy (TUMT), acupuncture, yoga and biofeedback/pelvic floor electrical stimulation have also been used. Rick Modderman from the patient and the physician), frustration, lack of immediate results and fear can all lead to inadequate and ineffective treatment. With a comprehensive approach targeting the cause, symptoms and disease manifestations, prostatitis can certainly be treatable, curable and, at a minimum, manageable. I was in rehab for four weeks and was released on Christmas Eve. Now that I look back on it, I was in a hurry to get on with my life. It would have been better for me to stay for a few more weeks to firm up all aspects of my spinal cord injury – bowel and bladder function, strength training and flexibility, more information on what to expect as I age, more information on what ‘outside/real world’ resources were available to me at that time, etc. Today, my life is busy. I recently moved to Denver due to a job change. From a wheelchair perspective there is not one flat spot in this town! After my injury I went to college where I met a ton of people with disabilities. In my opinion, prostatitis is difficult because of two reasons. First, there is a lack of recognition of the disease - both on the part of physicians as well as patients. Prostatitis is the great urological mimicker. Oftentimes, it is misdiagnosed as just BPH, chronic testicular pain, chronic low back pain, overactive bladder or sexual dysfunction (especially in younger men). Periodically, prostatitis symptoms are so mild and intermittent that they are often ignored by patients or just dismissed as something else. A delayed diagnosis, oftentimes taking years, leads to the second issue - undertreatment. Impatience (both The anatomy of the prostate. understanding and using the resources around me. Having a fat rolodex of contacts makes my life much easier and more enjoyable. It also allows me to give back with the most impact for the disabled community. If I had one wish, it wouldn’t necessarily be to have not had this motorcycle accident. I’ve learned a great deal from this and am still learning. I believe that being paralyzed and in a chair is more often a problem for the able bodied world than for me personally. I am happy at age 42. I get the job done and do most everything I want to. My being in a chair is more of a speed bump in life compared to conquering a mountain. With no disrespect to the kind, able bodies of the world, I get asked a lot of questions that negatively impact my confidence. I get asked if I need a door opened multiple times a day. Yet, every day I open doors just fine. Yes, I am out there shopping, running errands and working like almost everyone else. Many of us in wheelchairs try very hard to be as independent as possible. I would probably wish for one of two things to happen. One, for everyone to experience being paralyzed for three days. The world would have such a better understanding of the issues and real needs of those with disabilities. People may also realize that whatever they may be going through at the time might not be that bad. I would also wish for my bowel, bladder and sexual function to go back to the way it was when I was 21! Survivorship to me means independence. I’ve pushed lawn mowers, hand washed my own car, am successfully employed and have volunteered and given back to my community. The big aspects of survivorship for me are obtaining, Join TUCC Foundation for our first annual patient survivorship picnic from 1:00 – 4:00 p.m. on Sunday, June 7 at TUCC. More information about this event can be found in the TUCC Foundation section of the newsletter. Newsflash – The Effectiveness of Prostate Cancer Screenings Richard Augspurger, M.D., TUCC Medical Director Much conversation has focused on the effectiveness of prostate cancer screenings in the U.S. over the past few weeks. On March 26, the New England Journal of Medicine published a decade long study of 75,000 men indicating that there is no early mortality benefit from annual screenings. The Journal also published a 15-year European study in the same issue that found a 20 percent reduction in the mortality rate of 182,000 men. This varied data - noted as inconclusive even by some of the authors of the studies - is presenting mixed messages to the general public. Prostate cancer is now the second leading cause of death among American men. In Colorado alone, 3,210 cases were diagnosed in 2008. Controversy has surrounded prostate cancer screenings since the advent of the Prostate Specific Antigen (PSA) test. While not perfect, it is the best tool available today to diagnose the slow-growing disease. What we do know is that when prostate cancer is diagnosed in its earliest stages, the disease is treatable and survivable, with cure rates greater than 80 percent. Before PSA screenings, TUCC physicians could diagnose up to 40 percent of prostate cancer patients as metastatic. Today, thanks to screenings and early detection, it is incredibly rare for us to diagnose a metastatic patient. Abandoning prostate cancer screenings without further investigation and conclusive data is not the answer. At TUCC, we recommend that all men participate in annual prostate cancer screenings (PSA and DRE examinations) beginning at age 50. African-American men and men with a positive family history should begin these screenings at age 40. Only then can patients make informed treatment decisions with their physicians. Patient Education TUCC/Krames Online Portal At TUCC, we know that beginning the treatment process for any urologic condition can seem daunting to our patients. And while a wealth of information can be found on the Internet, how can you be sure it’s correct? In order to provide our patients with clinically accurate patient education materials, TUCC launched an online patient education portal last fall. This particular portal provides users with access to more than 4,000 topics relating to urology, general health and medicine. Users can also search for descriptions of 33,000 different prescription medications and find information on their own personal prescription. The TUCC/Krames Online Portal can be accessed from the Patient Conditions section of the TUCC Web site. We encourage all patients to utilize it as a 24-hour-a-day resource. 7 IN FOCUS 6 Upcoming Foundation Events (continued) October 20, 2009 Annual Presentation on Nutrition and Supplements 7:00 p.m. PPA Event Center 2105 Decatur Street Denver, CO 80211 TUCC Foundation is excited to bring Mark Moyad, M.D., back to Colorado for an 11th year. This is a free seminar for those interested in cancer prevention and those living with cancer. Dr. Moyad is the primary author of more than 100 medical articles, an author or co-author of five books and the editor-in-chief of the medical journal “Seminars in Preventive & Alternative Medicine” by Elsevier. His presentation is the premier update on nutrition and supplements for urologic cancers in Colorado. Prostate Cancer Education Video TUCC Foundation and the Center for African American Health are currently filming a five minute video focused on what men need to know about prostate cancer screenings. The video seeks to dispel the myths associated with screening and encourage men to take charge of their health. Stay tuned for its release on the TUCC Foundation Web site in September 2009. To learn more about any of these events or to make a donation to TUCC Foundation, please call 303.783.2777 or visit www.tucc.com/foundation. Patient Survivorship After the ambulance picked me up and rushed me to the hospital, I remember one specific thing. When I was on the metal slab – as I call it – I remember lots of people (physicians and nurses) running around me poking and probing. I was on my back and staring up at all of the different faces around me. I wasn’t feeling any pain, except for my left shoulder, and was curious what all the rush was about. At one point a trauma nurse looked down at my face and asked me how high I could lift my arms. My left shoulder was killing me. I was lying flat on my back on this metal slab and was very confused. My arms were on my belly and I could barely lift them up. She leaned over and grabbed both my wrists TUCC Clinical Research Department Awarded Acceptance into Society of Urologic Oncology Clinical Trials Consortium In February 2009, the TUCC clinical research department was awarded acceptance into the Society of Urologic Oncology Clinical Trials Consortium (SUO-CTC). The SUO-CTC is a national alliance of leading academic and community based urologic oncologists committed to furthering urologic research. The SUO-CTC pursues clinical trials in concert with the pharmaceutical industry to find medicines and treatments to tackle urological disorders including bladder cancer, prostate cancer and renal cancer. TUCC is one of only 11 large urology groups in the country to be accepted into the SUO-CTC. The TUCC clinical research department actively initiates and participates in local and national clinical trials focused on advancing the treatment of bladder cancer, prostate cancer, renal cancer, testicular cancer and other urologic conditions. To learn more about the clinical trials currently offered at TUCC, please consult the back side of this newsletter or visit www.tucc.com. Value Added Urology at TUCC Rick Modderman On October 9, 1987, I broke my back in a motorcycle accident. I was just 21 years old. As I was riding on a winding road in Northern California, I lost control of the bike and drove head on into a curb. The front wheel of the bike went up and the back wheel launched my body forward. My chest hit the handle bars stopping my upper body momentum. My legs went over my head and later at the hospital my doctor said that my ankles probably made it to my ears. I broke five vertebrae in the accident – T4 through T8. I also broke three ribs (two on one side and one on the other) where they connect to the spine. The ribs punctured the sacks around my lungs. Today, I am labeled a complete T4 paraplegic. 3 Stephen Ruyle, M.D., TUCC President and pulled my arms up over behind my head. The pain was unbearable and I let the expletives fly. Then I passed out. I woke up many hours later with tubes just beneath both armpits as well as in other places throughout my body. What happened? The ribs that punctured my lung cavities were going to cause my lungs to collapse. I needed to get the fluid drained immediately. Yet, my blood pressure was too low to receive any anesthesia/pain killers prior to that nurse ripping my arms up over my head so the doctor could poke a hole in my chest and insert a tube. After I was stabilized, it was off to surgery to repair my spine. The surgeon put two Harrington rods along with bone removed from my left hip back on my spine to give it some stability. I have since broken those rods following many sports activities and a car accident. A doctor said it would take a hammer and chisel to remove them. No thank you! Physical therapy was next. As a 21-year-old who was in good shape, physical therapy was like a four week gym challenge. The physical aspect of my injury has always been easier to deal with than the mental aspect. While in rehab, I focused on the physical skills and worked hard to figure out my limitations. It is the ‘real world’ mental aspects that I find most challenging. At rehab, I focused on learning and mastering my transfers to the bed, car, shower bench, etc. Learning to do wheelies and going up and down curbs was actually fun and have saved me a lot of time over the years. Why should I go around a building to find a ramp when I can just pop up a curb to get inside? We are experiencing extraordinarily difficult economic times where getting the most value for your money is paramount. This has led me to further examine the multiple services provided by TUCC which enhance the value of the urology experience for patients and referring physicians. These services are provided at no additional expense. For instance, did you know that all TUCC clinical personnel are required to obtain basic life support certification every two years? For registered nurses and physicians, advanced cardiac life support training is also required every two years. Hopefully a patient will never need emergency life support at TUCC, but we are ready in case such a rare event occurs. Did you know that TUCC runs three support groups for prostate cancer, bladder cancer and interstitial cystitis patients? In the near future we will also be establishing a urological support group for our patients with spinal cord injury. We are also focused on improving the overall health of our patients through quarterly educational seminars on nutrition and exercise and our sponsorship of an annual presentation on nutrition and supplements given by Mark Moyad, M.D. This presentation is considered to be the premier update on nutrition and supplements for urologic cancers in Colorado. Throughout the year, TUCC employees volunteer their time and expertise at prostate cancer and men’s health screenings including the 9Health Fair, the Center for African American Health’s annual health fair and other community events. TUCC Foundation, our nonprofit, 501 (c)(3) public charity, promotes community wide urologic education and provides needed financial assistance to urologic patients and TUCC employees. This year, TUCC also hosted our first educational seminar for primary care physicians and their staff to review current topics in urology. Our nationally recognized research department provides patients access to cutting edge treatments for urologic diseases. The department also hosts a quarterly speaker who is an expert in their field to keep TUCC physicians up-to-date on advancements in urologic research. For our patients undergoing surgery to remove their prostate, we provide training on pelvic floor muscle exercises by a board certified physical therapist. This helps promote the return of urinary continence following surgery. We have also established a penile rehabilitation program for the treatment of erectile dysfunction following prostate cancer surgery. Our nurses provide additional education and support for all surgery patients and contact patients following every biopsy and procedure performed in our surgery center. 4 TUCC Foundation Advancing urologic care in the Rocky Mountain region through advocacy, research, education and support. Patient Support Recent Foundation Events TUCC Penile Rehabilitation Program Erectile dysfunction continues to be one of the most common problems experienced by men following a da Vinci prostatectomy surgery. This issue can be a difficult process for men and their partners to go through. Following surgery it can take one to three years of natural recovery time for a man to see improvement in his erectile function. However, there is a clinical option for patients looking to recover from their surgical procedure - the TUCC penile rehabilitation program. Value Added Urology at TUCC (continued) The TUCC standards committee reviews our clinical outcomes and makes suggestions on how to improve quality and decrease adverse events. We have a morbidity and mortality conference every two months to review complications in an effort to improve our quality of care. Our physicians are required to undertake 30 hours of category 1 continuing medical education on a yearly basis (many do more). We have a monthly tumor board to review the cases of our most challenging cancer patients. This meeting is attended by all of the TUCC physicians and three of Colorado’s most prominent urologic oncologists. TUCC also has a monthly journal club to keep physicians up-to-date on the latest medical literature. Our staff attend regularly scheduled educational seminars taught by TUCC physicians that provide further understanding of urological diseases and treatments. In addition, we have regular meetings to review difficult kidney and ureteral stone cases. All of our committees, educational seminars and meetings promote the value of continuing education and the TUCC mission of excellence in urology. In my experience, very few physicians or practices go to this extent to provide such a high level of value added medical care. However, at TUCC we are always striving to improve and welcome suggestions from patients and referring physicians on what we can do better. For more information on value added services at TUCC, visit www.tucc.com or www.tucc.com/foundation. Chris Hitt, L.P.N., manager of the penile rehabilitation program, with a patient. TUCC established this program for our da Vinci prostatectomy patients four years ago. It serves as an important component of the prostate cancer treatment process. Patients who elect to participate are offered treatment options designed to facilitate recovery and help them attain and maintain an erection. Patients are encouraged to begin the program in the weeks immediately following their prostatectomy. Only two in-office appointments are required. We will explain the various aspects of the program at the initial appointment. At the second appointment, patients will receive instructions on how to use the treatment options they’ve selected. Most other discussions can be completed over the phone. The TUCC penile rehabilitation program includes a mechanical device - the vacuum erection pump - and three different prescription medication options. Because the mechanical device and prescription medications will impact each individual differently, patients are invited to test all four rehabilitation options during their course of treatment. To learn more about the treatment options associated with this program, please contact Chris Hitt, L.P.N., at 303.762.7158 or visit www.tucc.com. January 31, 2009 Center for African American Health Annual Health Fair Approximately 1,000 people participated in the Center for African American Health's 7th Annual Health Fair on January 31st, setting a new attendance record. TUCC Foundation clinical volunteers provided free PSA and DRE examinations for 116 men attending the health fair. African–American men are at a higher risk of being diagnosed with prostate cancer than men of any other race. April 15, 2009 Male Urinary Incontinence and Erectile Dysfunction Seminar More than 200 people attended this annual presentation at the PPA Event Center. TUCC physicians, Richard Augspurger, M.D., and Jesse Mills, M.D., discussed the latest treatments available for urinary incontinence and erectile dysfunction. Because there are so many treatments available for these conditions, our goal was to provide attendees with the information needed to find a beneficial solution for themselves – and their partners. A wide range of treatment options were discussed including medication, penile implants, artificial urinary sphincters and male slings. Upcoming Foundation Events June 7, 2009 2009 Survivorship Picnic 1:00 p.m. – 4:00 p.m. The Urology Center of Colorado 2777 Mile High Stadium Circle Denver, CO 80211 This event will celebrate survivors of urologic conditions (prostate cancer, bladder cancer, kidney cancer, testicular cancer, spinal cord injury and interstitial cystitis patients). Survivors and their families and friends develop a bond that follows a life changing diagnosis and the ups and downs of treatment. A survivor’s hope and perseverance serves as an inspiration to all of us. The Survivorship Picnic will feature a display of classic cars from the Old Car Council of Colorado, survivorship speakers, catered BBQ courtesy of PRN Medical, live music, interactive survivorship booths, educational information, giveaways and much more. August 5 and November 4, 2009 Quarterly Nutrition and Exercise Presentations 6:00 p.m. The Urology Center of Colorado 2777 Mile High Stadium Circle Denver, CO 80211 Nutrition and exercise play a key role the urologic treatment process. The August 5th presentation will focus on cardiovascular health – nutrition and exercise. The November 4th presentation will highlight weight loss and exercise. Registration for both presentations is capped at 40 people. Please call 303.762.7666 or 877.712.3111 (toll-free) to register. August 29, 2009 5th Annual Classic Aircraft and Car Show 9:00 a.m. – 3:00 p.m. Front Range Airport 5200 Front Range Parkway Watkins, CO 80137 TUCC Foundation is a proud partner of this event that brings unique classic and custom cars, aircraft and motorcycles to Coloradans. As a kick-off to Prostate Cancer Awareness Month, volunteers will offer free PSA and DRE examinations and educational materials to those men attending the show from 9:00 a.m. – 12:00 p.m. September 26, 2009 Annual Men’s Health Screening 8:00 a.m. – 12:00 p.m. Inner City Health Center 3800 York Street Denver, CO 80205 Each year, TUCC Foundation hosts a comprehensive men’s health screening for the local community as part of Prostate Cancer Awareness Month. The key to a good prostate cancer diagnosis is early detection through annual screenings. In 2009, TUCC Foundation will partner with the Center for African American Health to hold this annual event at Inner City Health Center. Participating men can take part in numerous screening opportunities on September 26th including prostate cancer, low testosterone and vitamin D. 5 4 TUCC Foundation Advancing urologic care in the Rocky Mountain region through advocacy, research, education and support. Patient Support Recent Foundation Events TUCC Penile Rehabilitation Program Erectile dysfunction continues to be one of the most common problems experienced by men following a da Vinci prostatectomy surgery. This issue can be a difficult process for men and their partners to go through. Following surgery it can take one to three years of natural recovery time for a man to see improvement in his erectile function. However, there is a clinical option for patients looking to recover from their surgical procedure - the TUCC penile rehabilitation program. Value Added Urology at TUCC (continued) The TUCC standards committee reviews our clinical outcomes and makes suggestions on how to improve quality and decrease adverse events. We have a morbidity and mortality conference every two months to review complications in an effort to improve our quality of care. Our physicians are required to undertake 30 hours of category 1 continuing medical education on a yearly basis (many do more). We have a monthly tumor board to review the cases of our most challenging cancer patients. This meeting is attended by all of the TUCC physicians and three of Colorado’s most prominent urologic oncologists. TUCC also has a monthly journal club to keep physicians up-to-date on the latest medical literature. Our staff attend regularly scheduled educational seminars taught by TUCC physicians that provide further understanding of urological diseases and treatments. In addition, we have regular meetings to review difficult kidney and ureteral stone cases. All of our committees, educational seminars and meetings promote the value of continuing education and the TUCC mission of excellence in urology. In my experience, very few physicians or practices go to this extent to provide such a high level of value added medical care. However, at TUCC we are always striving to improve and welcome suggestions from patients and referring physicians on what we can do better. For more information on value added services at TUCC, visit www.tucc.com or www.tucc.com/foundation. Chris Hitt, L.P.N., manager of the penile rehabilitation program, with a patient. TUCC established this program for our da Vinci prostatectomy patients four years ago. It serves as an important component of the prostate cancer treatment process. Patients who elect to participate are offered treatment options designed to facilitate recovery and help them attain and maintain an erection. Patients are encouraged to begin the program in the weeks immediately following their prostatectomy. Only two in-office appointments are required. We will explain the various aspects of the program at the initial appointment. At the second appointment, patients will receive instructions on how to use the treatment options they’ve selected. Most other discussions can be completed over the phone. The TUCC penile rehabilitation program includes a mechanical device - the vacuum erection pump - and three different prescription medication options. Because the mechanical device and prescription medications will impact each individual differently, patients are invited to test all four rehabilitation options during their course of treatment. To learn more about the treatment options associated with this program, please contact Chris Hitt, L.P.N., at 303.762.7158 or visit www.tucc.com. January 31, 2009 Center for African American Health Annual Health Fair Approximately 1,000 people participated in the Center for African American Health's 7th Annual Health Fair on January 31st, setting a new attendance record. TUCC Foundation clinical volunteers provided free PSA and DRE examinations for 116 men attending the health fair. African–American men are at a higher risk of being diagnosed with prostate cancer than men of any other race. April 15, 2009 Male Urinary Incontinence and Erectile Dysfunction Seminar More than 200 people attended this annual presentation at the PPA Event Center. TUCC physicians, Richard Augspurger, M.D., and Jesse Mills, M.D., discussed the latest treatments available for urinary incontinence and erectile dysfunction. Because there are so many treatments available for these conditions, our goal was to provide attendees with the information needed to find a beneficial solution for themselves – and their partners. A wide range of treatment options were discussed including medication, penile implants, artificial urinary sphincters and male slings. Upcoming Foundation Events June 7, 2009 2009 Survivorship Picnic 1:00 p.m. – 4:00 p.m. The Urology Center of Colorado 2777 Mile High Stadium Circle Denver, CO 80211 This event will celebrate survivors of urologic conditions (prostate cancer, bladder cancer, kidney cancer, testicular cancer, spinal cord injury and interstitial cystitis patients). Survivors and their families and friends develop a bond that follows a life changing diagnosis and the ups and downs of treatment. A survivor’s hope and perseverance serves as an inspiration to all of us. The Survivorship Picnic will feature a display of classic cars from the Old Car Council of Colorado, survivorship speakers, catered BBQ courtesy of PRN Medical, live music, interactive survivorship booths, educational information, giveaways and much more. August 5 and November 4, 2009 Quarterly Nutrition and Exercise Presentations 6:00 p.m. The Urology Center of Colorado 2777 Mile High Stadium Circle Denver, CO 80211 Nutrition and exercise play a key role the urologic treatment process. The August 5th presentation will focus on cardiovascular health – nutrition and exercise. The November 4th presentation will highlight weight loss and exercise. Registration for both presentations is capped at 40 people. Please call 303.762.7666 or 877.712.3111 (toll-free) to register. August 29, 2009 5th Annual Classic Aircraft and Car Show 9:00 a.m. – 3:00 p.m. Front Range Airport 5200 Front Range Parkway Watkins, CO 80137 TUCC Foundation is a proud partner of this event that brings unique classic and custom cars, aircraft and motorcycles to Coloradans. As a kick-off to Prostate Cancer Awareness Month, volunteers will offer free PSA and DRE examinations and educational materials to those men attending the show from 9:00 a.m. – 12:00 p.m. September 26, 2009 Annual Men’s Health Screening 8:00 a.m. – 12:00 p.m. Inner City Health Center 3800 York Street Denver, CO 80205 Each year, TUCC Foundation hosts a comprehensive men’s health screening for the local community as part of Prostate Cancer Awareness Month. The key to a good prostate cancer diagnosis is early detection through annual screenings. In 2009, TUCC Foundation will partner with the Center for African American Health to hold this annual event at Inner City Health Center. Participating men can take part in numerous screening opportunities on September 26th including prostate cancer, low testosterone and vitamin D. 5 IN FOCUS 6 Upcoming Foundation Events (continued) October 20, 2009 Annual Presentation on Nutrition and Supplements 7:00 p.m. PPA Event Center 2105 Decatur Street Denver, CO 80211 TUCC Foundation is excited to bring Mark Moyad, M.D., back to Colorado for an 11th year. This is a free seminar for those interested in cancer prevention and those living with cancer. Dr. Moyad is the primary author of more than 100 medical articles, an author or co-author of five books and the editor-in-chief of the medical journal “Seminars in Preventive & Alternative Medicine” by Elsevier. His presentation is the premier update on nutrition and supplements for urologic cancers in Colorado. Prostate Cancer Education Video TUCC Foundation and the Center for African American Health are currently filming a five minute video focused on what men need to know about prostate cancer screenings. The video seeks to dispel the myths associated with screening and encourage men to take charge of their health. Stay tuned for its release on the TUCC Foundation Web site in September 2009. To learn more about any of these events or to make a donation to TUCC Foundation, please call 303.783.2777 or visit www.tucc.com/foundation. Patient Survivorship After the ambulance picked me up and rushed me to the hospital, I remember one specific thing. When I was on the metal slab – as I call it – I remember lots of people (physicians and nurses) running around me poking and probing. I was on my back and staring up at all of the different faces around me. I wasn’t feeling any pain, except for my left shoulder, and was curious what all the rush was about. At one point a trauma nurse looked down at my face and asked me how high I could lift my arms. My left shoulder was killing me. I was lying flat on my back on this metal slab and was very confused. My arms were on my belly and I could barely lift them up. She leaned over and grabbed both my wrists TUCC Clinical Research Department Awarded Acceptance into Society of Urologic Oncology Clinical Trials Consortium In February 2009, the TUCC clinical research department was awarded acceptance into the Society of Urologic Oncology Clinical Trials Consortium (SUO-CTC). The SUO-CTC is a national alliance of leading academic and community based urologic oncologists committed to furthering urologic research. The SUO-CTC pursues clinical trials in concert with the pharmaceutical industry to find medicines and treatments to tackle urological disorders including bladder cancer, prostate cancer and renal cancer. TUCC is one of only 11 large urology groups in the country to be accepted into the SUO-CTC. The TUCC clinical research department actively initiates and participates in local and national clinical trials focused on advancing the treatment of bladder cancer, prostate cancer, renal cancer, testicular cancer and other urologic conditions. To learn more about the clinical trials currently offered at TUCC, please consult the back side of this newsletter or visit www.tucc.com. Value Added Urology at TUCC Rick Modderman On October 9, 1987, I broke my back in a motorcycle accident. I was just 21 years old. As I was riding on a winding road in Northern California, I lost control of the bike and drove head on into a curb. The front wheel of the bike went up and the back wheel launched my body forward. My chest hit the handle bars stopping my upper body momentum. My legs went over my head and later at the hospital my doctor said that my ankles probably made it to my ears. I broke five vertebrae in the accident – T4 through T8. I also broke three ribs (two on one side and one on the other) where they connect to the spine. The ribs punctured the sacks around my lungs. Today, I am labeled a complete T4 paraplegic. 3 Stephen Ruyle, M.D., TUCC President and pulled my arms up over behind my head. The pain was unbearable and I let the expletives fly. Then I passed out. I woke up many hours later with tubes just beneath both armpits as well as in other places throughout my body. What happened? The ribs that punctured my lung cavities were going to cause my lungs to collapse. I needed to get the fluid drained immediately. Yet, my blood pressure was too low to receive any anesthesia/pain killers prior to that nurse ripping my arms up over my head so the doctor could poke a hole in my chest and insert a tube. After I was stabilized, it was off to surgery to repair my spine. The surgeon put two Harrington rods along with bone removed from my left hip back on my spine to give it some stability. I have since broken those rods following many sports activities and a car accident. A doctor said it would take a hammer and chisel to remove them. No thank you! Physical therapy was next. As a 21-year-old who was in good shape, physical therapy was like a four week gym challenge. The physical aspect of my injury has always been easier to deal with than the mental aspect. While in rehab, I focused on the physical skills and worked hard to figure out my limitations. It is the ‘real world’ mental aspects that I find most challenging. At rehab, I focused on learning and mastering my transfers to the bed, car, shower bench, etc. Learning to do wheelies and going up and down curbs was actually fun and have saved me a lot of time over the years. Why should I go around a building to find a ramp when I can just pop up a curb to get inside? We are experiencing extraordinarily difficult economic times where getting the most value for your money is paramount. This has led me to further examine the multiple services provided by TUCC which enhance the value of the urology experience for patients and referring physicians. These services are provided at no additional expense. For instance, did you know that all TUCC clinical personnel are required to obtain basic life support certification every two years? For registered nurses and physicians, advanced cardiac life support training is also required every two years. Hopefully a patient will never need emergency life support at TUCC, but we are ready in case such a rare event occurs. Did you know that TUCC runs three support groups for prostate cancer, bladder cancer and interstitial cystitis patients? In the near future we will also be establishing a urological support group for our patients with spinal cord injury. We are also focused on improving the overall health of our patients through quarterly educational seminars on nutrition and exercise and our sponsorship of an annual presentation on nutrition and supplements given by Mark Moyad, M.D. This presentation is considered to be the premier update on nutrition and supplements for urologic cancers in Colorado. Throughout the year, TUCC employees volunteer their time and expertise at prostate cancer and men’s health screenings including the 9Health Fair, the Center for African American Health’s annual health fair and other community events. TUCC Foundation, our nonprofit, 501 (c)(3) public charity, promotes community wide urologic education and provides needed financial assistance to urologic patients and TUCC employees. This year, TUCC also hosted our first educational seminar for primary care physicians and their staff to review current topics in urology. Our nationally recognized research department provides patients access to cutting edge treatments for urologic diseases. The department also hosts a quarterly speaker who is an expert in their field to keep TUCC physicians up-to-date on advancements in urologic research. For our patients undergoing surgery to remove their prostate, we provide training on pelvic floor muscle exercises by a board certified physical therapist. This helps promote the return of urinary continence following surgery. We have also established a penile rehabilitation program for the treatment of erectile dysfunction following prostate cancer surgery. Our nurses provide additional education and support for all surgery patients and contact patients following every biopsy and procedure performed in our surgery center. Issue Six Spring 2009 8 Current Clinical Trials The Urology Center TUCC is now enrolling patients in the following clinical trials: spread from the kidney to another part of the body. Over-active Bladder We are currently enrolling male and female patients in a clinical trial for the treatment of over-active bladder. If you have been diagnosed with over-active bladder or have experienced symptoms such as urinary frequency, urgency or urge incontinence, you may qualify for this study. Benign Prostatic Hyperplasia (BPH) We are currently enrolling patients in a clinical trial for the treatment of an enlarging prostate. Bladder Cancer We are currently enrolling bladder cancer patients in a study for those who are newly diagnosed or experiencing recurrent low-grade tumors. Kidney Cancer Newly diagnosed kidney cancer patients interested in enrolling in this trial must have undergone a nephrectomy or be scheduled to have the procedure. Lesions (cancer cells) must have Phase I Vaccine Study Requirements for enrollment: • Diagnosed with prostate cancer • Must have undergone treatment for the disease • PSA must be rising OR The Urology Center of Colorado 2777 Mile High Stadium Circle Denver, CO 80211 • Diagnosed with renal cell or bladder cancer • Can be Stage II, III or IV • Cancer must not have metastasized to distant areas of the body Prostate Cancer We are currently enrolling prostate cancer patients in a study for men on hormonal therapy. Requirements for enrollment: • PSA must be rising • Cancer must not have spread to the bones For all study participants: of Colorado IN FOCUS Study medication and procedures are provided at no cost. Participation in all studies is voluntary. For more information about clinical trials at TUCC, please speak with your physician or visit www.tucc.com. Condition Spotlight Prostatitis Craig Sakurada, M.D. The prostate is a walnut sized gland located at the base of the bladder. Its main function as a secondary sex gland is to produce fluid and nutrients that allow sperm to live outside the body. Unfortunately, once fertility is no longer an issue for men, the gland often causes more problems than benefits. One very common problem affecting men of all ages is prostatitis. According to some estimates, men have a 5 -10 percent chance of being diagnosed with some form of prostatitis during their lifetime. According to the American Academy of Family Physicians, nearly 25 percent of physician visits for genitourinary complaints can be attributed to prostatitis. Prostatitis accounts for nearly two million outpatient medical visits per year, costing more than 6 billion dollars annually. Autopsy studies have revealed an even higher prevalence of prostatitis in men 64- 86 percent. Why are so many men suffering from prostatitis? The answer, unfortunately, is not so clear cut. For all of the great advancements in medicine, prostatitis is still a poorly understood disease. This is what we do know. Prostatitis is, by definition, inflammation of the prostate gland. What causes the inflammation, however, is the million dollar question. The National Institutes of Health classifies prostatitis into four categories: 1. Acute bacterial prostatitis: These patients tend to be very sick with high fevers. They experience burning with urination, extremely tender prostates on examination and significant voiding dysfunction. 2. Chronic bacterial prostatitis and 3. Chronic non-bacterial prostatitis / prostatodynia / chronic pelvic pain syndrome: These patients tend to have more chronic, low grade and often intermittent symptoms. The symptoms can range from intermittent, low grade burning with urination, urinary frequency, urgency and slow urinary stream to pelvic/ testicular/groin/low back pain. Patients may also experience burning, pain and even blood with or after ejaculation as well as sexual dysfunction (premature ejaculation, erectile dysfunction). Patients may often feel tired, lethargic, run down and run low grade intermittent fevers and chills (with bacterial prostatitis). 4. Asymptomatic inflammatory prostatitis: Typically, these patients do not complain of pain or exhibit symptoms. While these disease categories do exist, ‘pigeon-holing’ patients into one or another can be detrimental and shortsighted. The most challenging groups to treat are the chronic bacterial and chronic non-bacterial prostatitis patients. The vast majority of these patients are classified into the chronic non-bacterial prostatitis category. It is very difficult to identify and isolate a treatable bacteria in many, if not most, patients who present with prostatitis symptoms. However, a significant portion of these patients do respond favorably to antibiotics, which raises concerns about such defined labels. Some medical professionals believe that this is all a spectrum of the same disease, just with varying degrees of clinical symptoms and bacterial detectability. Others feel that there are truly non-infectious disease causes for prostatitis. One interesting theory currently under investigation is that some forms of prostatitis may be classified as autoimmune disorders, in which the body fails to recognize normal prostate tissue and mistakenly attacks it causing inflammation. Similar autoimmune disorders already exist within the body such as rheumatoid arthritis. Others theorize that the reflux of urine into the prostate ducts, stress, pelvic floor dysfunction, infrequent ejaculation or various foods and beverages may contribute to prostatitis.
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