1. No category

MSDS# 0831 COVER SHEET
28340
Surfact-Pak Detergent Sampler
Component #
1854560
1854540
1854530
0028314
0028316
0028320
0028324
0028328
0028332
0028336
Description
CHAPS
Octyl β-Glucoside
Octyl β-Thioglucoside
Surfact-Amps X-100
Surfact-Amps 35
Surfact-Amps 20
Surfact-Amps NP-40
Surfact-Amps 80
Surfact-Amps X-114
Surfact-Amps 58
Life Science Research
PO Box 117
Rockford, Il
(815) 968-0747
Pierce Biotechnology, Inc
3747 N. Meridian Road
61105
(815) 968-7316 fax
www.thermo.com
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Part of Thermo Fisher Scientific
Surfact-Amps 35
2.
Material Safety Data Sheet
1.
Product and company identification
: Surfact-Amps 35
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
2.
:
:
:
:
:
:
Manufacturer
0028316 0028316B 1881060
2437
5/18/2010.
5/18/2010.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747
800.874.3723
Emergency overview
Medical conditions
aggravated by overexposure
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
: Liquid.
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
: WARNING !
CAUSES EYE IRRITATION. MAY BE HARMFUL IF SWALLOWED. MAY CAUSE
SKIN IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN
DAMAGE.
Harmful if swallowed. Severely irritating to eyes. Slightly irritating to the skin. Avoid
exposure - obtain special instructions before use. Do not breathe vapor or mist. Do not
ingest. Do not get in eyes. Avoid contact with skin and clothing. Contains material that
can cause target organ damage. Wash thoroughly after handling.
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: No known significant effects or critical hazards.
: Harmful if swallowed.
Ingestion
: Slightly irritating to the skin.
Skin
: Severely irritating to eyes. Risk of serious damage to eyes.
Eyes
Potential chronic health effects
Chronic effects
: Contains material that can cause target organ damage.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: Pre-existing digestive disorders and disorders involving any other target organs
mentioned in this MSDS as being at risk may be aggravated by over-exposure to this
product.
The preparation is classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Xi; R41
Human health hazards
: Risk of serious damage to eyes.
See toxicological information (section 11)
3.
Composition/information on ingredients
United States
Name
Brij 35
CAS number
9002-92-0
Europe
Substance/preparation
Ingredient name
%
7 - 10
: Preparation
CAS
number
9002-92-0
Brij 35
%
EC number
7 - 10
500-002-6
Classification
[1]
Xn; R22
Xi; R41, R38
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
Occupational exposure limits, if available, are listed in section 8.
1/8
5/18/2010.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: Contains material which causes damage to the following organs: the nervous system,
skin, eyes.
Contains material which may cause damage to the following organs: kidneys, lungs,
liver, bladder, gastrointestinal tract, central nervous system (CNS).
Over-exposure signs/symptoms
Inhalation
: No specific data.
Ingestion
: No specific data.
Skin
: Adverse symptoms may include the following:
irritation
redness
Eyes
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Hazards identification
Physical state
OSHA/HCS status
Hazards identification
Developmental effects
Fertility effects
Target organs
2/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps 35
Surfact-Amps 35
4.
6.
First aid measures
Inhalation
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. It may be dangerous to the person providing aid to give mouth-tomouth resuscitation. Get medical attention. If unconscious, place in recovery position
and get medical attention immediately. Maintain an open airway. Loosen tight clothing
such as a collar, tie, belt or waistband.
Ingestion
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention. Never give anything by mouth to an
unconscious person. If unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen tight clothing such as a collar,
tie, belt or waistband.
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Continue to rinse for at least 10 minutes. Get medical attention if symptoms
occur. Wash clothing before reuse. Clean shoes thoroughly before reuse.
Eye contact
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention. Chemical burns must be treated promptly by a physician.
Protection of first-aiders
: No action shall be taken involving any personal risk or without suitable training. It may
be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
See section 11 for more detailed information on health effects and symptoms.
Accidental release measures
Large spill
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Small spill
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
7.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest. If
during normal use the material presents a respiratory hazard, use only with adequate
ventilation or wear appropriate respirator. Keep in the original container or an approved
alternative made from a compatible material, kept tightly closed when not in use. Empty
containers retain product residue and can be hazardous. Do not reuse container.
Storage
: Store between the following temperatures: 20 to 25°C (68 to 77°F). Store in accordance
with local regulations. Store in original container protected from direct sunlight in a dry,
cool and well-ventilated area, away from incompatible materials (see section 10) and
food and drink. Keep container tightly closed and sealed until ready for use. Containers
that have been opened must be carefully resealed and kept upright to prevent leakage.
Do not store in unlabeled containers. Use appropriate containment to avoid
environmental contamination.
Skin contact
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Hazardous combustion
products
Special protective
equipment for fire-fighters
6.
: In a fire or if heated, a pressure increase will occur and the container may burst.
8.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: Decomposition products may include the following materials:
carbon oxides
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
3/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Exposure controls/personal protection
Europe
No exposure limit value known.
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: If user operations generate dust, fumes, gas, vapor or mist, use process enclosures,
local exhaust ventilation or other engineering controls to keep worker exposure to
airborne contaminants below any recommended or statutory limits.
Hygiene measures
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
Respiratory
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
4/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps 35
8.
Surfact-Amps 35
Exposure controls/personal protection
Hands
Eyes
Skin
Environmental exposure
controls
9.
11 . Toxicological information
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
: Liquid.
: Clear Colorless.
: Soluble in the following materials: cold water and hot water.
10 . Stability and reactivity
Chemical stability
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Possibility of hazardous
reactions
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Conclusion/Summary
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
Carcinogenicity
Conclusion/Summary
EPA
-
NIOSH
None.
NTP
-
OSHA
None.
: Not available.
: Not available.
: Not available.
:
:
:
:
:
:
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
12 . Ecological information
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
Other adverse effects
: Will not occur.
13 . Disposal considerations
Result
LD50
Intraperitoneal
LD50 Intravenous
LD50 Oral
LD50 Oral
LD50
Subcutaneous
Species
Rat
Dose
125 mg/kg
Exposure
-
Rat
Rat
Rat
Rat
27 mg/kg
1000 mg/kg
8600 mg/kg
953 mg/kg
-
: No known significant effects or critical hazards.
: Not available.
: No known significant effects or critical hazards.
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
Hazardous waste
: The classification of the product may meet the criteria for a hazardous waste.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
14 . Transport information
: Not available.
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
: Not available.
DOT Classification
Not
regulated.
-
-
-
: Not available.
IATA-DGR Class
Not
regulated.
-
-
-
5/8
5/18/2010.
Biosciences Division
Pierce
IARC
-
Europe
11 . Toxicological information
United States
Acute toxicity
Product/ingredient name
Dodecan-1-ol, ethoxylated
ACGIH
-
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
Physical and chemical properties
Physical state
Color
Solubility
Classification
Product/ingredient name
Dodecan-1-ol, ethoxylated
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
6/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps 35
Surfact-Amps 35
14 . Transport information
16 . Other information
PG* : Packing group
Label requirements
: CAUSES EYE IRRITATION. MAY BE HARMFUL IF SWALLOWED. MAY CAUSE
SKIN IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN
DAMAGE.
Hazardous Material
Information System (U.S.A.)
:
15 . Regulatory information
United States
HCS Classification
U.S. Federal regulations
: Irritating material
Target organ effects
: United States inventory (TSCA 8b): All components are listed or exempted.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Dodecan-1-ol, ethoxylated
SARA 311/312 MSDS distribution - chemical inventory - hazard identification:
Dodecan-1-ol, ethoxylated: Immediate (acute) health hazard, Delayed (chronic) health
hazard
Canada inventory
EU regulations
: Not controlled under WHMIS (Canada).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: Canada inventory: All components are listed or exempted.
Hazard symbol or symbols
:
Risk phrases
Safety phrases
Irritant
: R41- Risk of serious damage to eyes.
: S26- In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice.
S39- Wear eye/face protection.
International regulations
International lists
0
Physical hazards
0
Flammability
0
Health
2
0
Instability
Special
: 5/18/2010.
: 5/18/2010.
Date of issue
Date of previous issue
: 7/27/2009.
Version
: 1.01
Indicates information that has changed from previously issued version.
: R22- Harmful if swallowed.
Full text of R-phrases
R41- Risk of serious damage to eyes.
referred to in sections 2 and
R38- Irritating to skin.
3 - Europe
: Xn - Harmful
Full text of classifications
Xi - Irritant
referred to in sections 2 and
3 - Europe
Date of printing
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): All components are listed or exempted.
7/8
5/18/2010.
Biosciences Division
Pierce
2
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
Canada
WHMIS (Canada)
Canadian lists
Health
Flammability
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
8/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
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Part of Thermo Fisher Scientific
Surfact-Amps NP-40
2.
Material Safety Data Sheet
1.
Product and company identification
Product name
Supplier
: Surfact-Amps NP-40
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
:
:
:
:
:
:
2.
Manufacturer
0028324
0797
5/18/2010.
5/18/2010.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747
800.874.3723
Emergency overview
Eyes
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
Medical conditions
aggravated by overexposure
: Liquid. [Clear to slightly hazy liquid.]
: Odorless.
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
: WARNING !
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. MAY CAUSE
ALLERGIC RESPIRATORY AND SKIN REACTION. MAY BE HARMFUL IF
SWALLOWED. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN
DAMAGE, BASED ON ANIMAL DATA.
3.
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: Irritating to respiratory system. May cause sensitization by inhalation.
: Harmful if swallowed.
Ingestion
: Irritating to skin. May cause sensitization by skin contact.
Skin
: Severely irritating to eyes. Risk of serious damage to eyes.
Eyes
Potential chronic health effects
Chronic effects
: Contains material that may cause target organ damage, based on animal data.
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Composition/information on ingredients
United States
Name
Nonidet P-40 Substitute
Europe
Substance/preparation
Ingredient name
CAS number
9016-45-9
%
7 - 10
: Preparation
CAS
number
9016-45-9
Nonidet P-40 Substitute
%
EC number
7 - 10
Classification
Xn; R22
Xi; R41,
R37/38
[1]
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
1/9
5/18/2010.
: Pre-existing respiratory, skin and digestive disorders and disorders involving any other
target organs mentioned in this MSDS as being at risk may be aggravated by overexposure to this product.
The preparation is classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Xi; R41
Human health hazards
: Risk of serious damage to eyes.
See toxicological information (section 11)
Harmful if swallowed. Severely irritating to eyes. Irritating to respiratory system and
skin. May cause sensitization by inhalation and skin contact. Avoid exposure - obtain
special instructions before use. Do not breathe vapor or mist. Do not ingest. Do not get
in eyes or on skin or clothing. Contains material that may cause target organ damage,
based on animal data. Use only with adequate ventilation. Keep container tightly closed
and sealed until ready for use. Wash thoroughly after handling.
Biosciences Division
Pierce
: No specific data.
: Adverse symptoms may include the following:
irritation
redness
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Ingestion
Skin
Hazards identification
Physical state
Odor
OSHA/HCS status
Hazards identification
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Developmental effects
: No known significant effects or critical hazards.
Fertility effects
: No known significant effects or critical hazards.
Target organs
: Contains material which may cause damage to the following organs: endocrine.
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
wheezing and breathing difficulties
asthma
2/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps NP-40
Surfact-Amps NP-40
3.
6.
Composition/information on ingredients
Occupational exposure limits, if available, are listed in section 8.
4.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
First aid measures
: Move exposed person to fresh air. If it is suspected that fumes are still present, the
rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep
person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest
occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous
to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention.
If unconscious, place in recovery position and get medical attention immediately.
Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.
In the event of any complaints or symptoms, avoid further exposure.
Inhalation
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention. Never give anything by mouth to an
unconscious person. If unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen tight clothing such as a collar,
tie, belt or waistband.
Ingestion
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Wash contaminated clothing thoroughly with water before removing or wear
gloves. Continue to rinse for at least 10 minutes. Get medical attention. In the event of
any complaints or symptoms, avoid further exposure. Wash clothing before reuse.
Clean shoes thoroughly before reuse.
Skin contact
Eye contact
Protection of first-aiders
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention. Chemical burns must be treated promptly by a physician.
: No action shall be taken involving any personal risk or without suitable training. If it is
suspected that fumes are still present, the rescuer should wear an appropriate mask or
self-contained breathing apparatus. It may be dangerous to the person providing aid to
give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water
before removing or wear gloves.
Large spill
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
Small spill
7.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Persons with a history of skin sensitization problems or asthma, allergies or chronic or
recurrent respiratory disease should not be employed in any process in which this
product is used. Do not get in eyes or on skin or clothing. Do not breathe vapor or mist.
Do not ingest. Use only with adequate ventilation. Wear appropriate respirator when
ventilation is inadequate. Keep in the original container or an approved alternative made
from a compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store between the following temperatures: 20 to 25°C (68 to 77°F). Store in accordance
with local regulations. Store in original container protected from direct sunlight in a dry,
cool and well-ventilated area, away from incompatible materials (see section 10) and
food and drink. Keep container tightly closed and sealed until ready for use. Containers
that have been opened must be carefully resealed and kept upright to prevent leakage.
Do not store in unlabeled containers. Use appropriate containment to avoid
environmental contamination.
See section 11 for more detailed information on health effects and symptoms.
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
: In a fire or if heated, a pressure increase will occur and the container may burst.
Hazardous combustion
products
: Decomposition products may include the following materials:
carbon oxides
Special protective
equipment for fire-fighters
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
8.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
3/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Exposure controls/personal protection
Europe
No exposure limit value known.
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
4/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps NP-40
8.
Surfact-Amps NP-40
Exposure controls/personal protection
11 . Toxicological information
Engineering measures
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor
or mist, use process enclosures, local exhaust ventilation or other engineering controls
to keep worker exposure to airborne contaminants below any recommended or statutory
limits.
Hygiene measures
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
Respiratory
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Hands
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
Eyes
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Environmental exposure
controls
9.
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Physical and chemical properties
Physical state
Color
Odor
Solubility
:
:
:
:
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Possibility of hazardous
reactions
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
: Will not occur.
5/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
Carcinogenicity
Conclusion/Summary
Classification
Product/ingredient name
Nonidet P-40 Substitute
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Conclusion/Summary
Result
LD50 Dermal
LD50 Dermal
LD50
Intraperitoneal
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
: Not available.
Species
Rabbit
Rabbit
Rat
Dose
2 mL/kg
2830 uL/kg
770 mg/kg
Exposure
-
Rat
Rat
Rat
Rat
Rat
3500 mg/kg
1310 mg/kg
4190 mg/kg
4000 mg/kg
2590 uL/kg
-
: Not available.
: Not available.
ACGIH
-
IARC
-
EPA
-
NIOSH
None.
NTP
-
OSHA
-
: Not available.
: Not available.
: Not available.
Europe
Liquid. [Clear to slightly hazy liquid.]
Colorless.
Odorless.
Easily soluble in the following materials: cold water and hot water.
10 . Stability and reactivity
Chemical stability
United States
Acute toxicity
Product/ingredient name
Nonidet P-40 Substitute
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
:
:
:
:
:
:
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
12 . Ecological information
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
Other adverse effects
: No known significant effects or critical hazards.
: Not available.
: No known significant effects or critical hazards.
6/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps NP-40
Surfact-Amps NP-40
13 . Disposal considerations
15 . Regulatory information
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
Hazardous waste
: The classification of the product may meet the criteria for a hazardous waste.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Canadian lists
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: The following components are listed: Octylphenol and its ethoxylates
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
Canada inventory
: Canada inventory: All components are listed or exempted.
EU regulations
Hazard symbol or symbols
:
Risk phrases
Safety phrases
Irritant
: R41- Risk of serious damage to eyes.
: S26- In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice.
S39- Wear eye/face protection.
14 . Transport information
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
DOT Classification
Not
regulated.
-
-
-
IATA-DGR Class
Not
regulated.
-
-
International regulations
International lists
PG* : Packing group
15 . Regulatory information
United States
HCS Classification
U.S. Federal regulations
: Irritating material
Sensitizing material
Target organ effects
: TSCA 8(a) PAIR: Nonidet P-40 Substitute
United States inventory (TSCA 8b): All components are listed or exempted.
16 . Other information
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Nonidet P-40 Substitute
SARA 311/312 MSDS distribution - chemical inventory - hazard identification:
Nonidet P-40 Substitute: Fire hazard, Immediate (acute) health hazard, Delayed
(chronic) health hazard
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
Canada
WHMIS (Canada)
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): All components are listed or exempted.
Label requirements
: CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. MAY CAUSE
ALLERGIC RESPIRATORY AND SKIN REACTION. MAY BE HARMFUL IF
SWALLOWED. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN
DAMAGE, BASED ON ANIMAL DATA.
Hazardous Material
Information System (U.S.A.)
:
Health
2
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
: Class D-2B: Material causing other toxic effects (Toxic).
Flammability
0
Health
2
0
Instability
Special
Date of printing
7/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: 5/18/2010.
8/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps NP-40
16 . Other information
: 5/18/2010.
Date of issue
Date of previous issue
: 5/18/2010.
Version
: 1.02
Indicates information that has changed from previously issued version.
Full text of R-phrases
: R22- Harmful if swallowed.
R41- Risk of serious damage to eyes.
referred to in sections 2 and
R37/38- Irritating to respiratory system and skin.
3 - Europe
: Xn - Harmful
Full text of classifications
Xi - Irritant
referred to in sections 2 and
3 - Europe
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
9/9
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Part of Thermo Fisher Scientific
Surfact-AmpsTM 80
2.
Material Safety Data Sheet
1.
Product and company identification
: Surfact-AmpsTM 80
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
:
:
:
:
:
:
Manufacturer
0028328 0028328B
1243
5/18/2010.
5/18/2010.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747
800.874.3723
Eyes
Medical conditions
aggravated by overexposure
Emergency overview
: MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
Slightly irritating to the eyes, skin and respiratory system. Avoid breathing vapor or mist.
Avoid contact with eyes. Avoid prolonged or repeated contact with skin. Use only with
adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash
thoroughly after handling.
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: Slightly irritating to the respiratory system.
Ingestion
: No known significant effects or critical hazards.
Skin
: Slightly irritating to the skin.
: Slightly irritating to the eyes.
Eyes
Potential chronic health effects
Chronic effects
: No known significant effects or critical hazards.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Developmental effects
: No known significant effects or critical hazards.
1/8
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Composition/information on ingredients
United States
Name
Tween 80
: Liquid.
: While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
5/18/2010.
: None known.
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
Hazards identification
Physical state
OSHA/HCS status
: No specific data.
: Adverse symptoms may include the following:
irritation
redness
: Adverse symptoms may include the following:
irritation
watering
redness
Ingestion
Skin
3.
2.
Hazards identification
Fertility effects
: No known significant effects or critical hazards.
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
CAS number
9005-65-6
%
7 - 10
Substance/preparation
: Preparation
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
4.
First aid measures
Inhalation
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. It may be dangerous to the person providing aid to give mouth-tomouth resuscitation. Get medical attention if adverse health effects persist or are
severe. If unconscious, place in recovery position and get medical attention
immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or
waistband.
Ingestion
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention if adverse health effects persist or are
severe. Never give anything by mouth to an unconscious person. If unconscious, place
in recovery position and get medical attention immediately. Maintain an open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.
2/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-AmpsTM 80
Surfact-AmpsTM 80
4.
7.
First aid measures
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Continue to rinse for at least 10 minutes. Get medical attention if symptoms
occur. Wash clothing before reuse. Clean shoes thoroughly before reuse.
Eye contact
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention if irritation occurs.
Protection of first-aiders
: No action shall be taken involving any personal risk or without suitable training. It may
be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
See section 11 for more detailed information on health effects and symptoms.
Skin contact
5.
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin and clothing.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store between the following temperatures: 20 to 25°C (68 to 77°F). Store in accordance
with local regulations. Store in original container protected from direct sunlight in a dry,
cool and well-ventilated area, away from incompatible materials (see section 10) and
food and drink. Keep container tightly closed and sealed until ready for use. Containers
that have been opened must be carefully resealed and kept upright to prevent leakage.
Do not store in unlabeled containers. Use appropriate containment to avoid
environmental contamination.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
: In a fire or if heated, a pressure increase will occur and the container may burst.
Hazardous combustion
products
: Decomposition products may include the following materials:
carbon oxides
Special protective
equipment for fire-fighters
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
6.
Handling and storage
Handling
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
8.
Accidental release measures
Personal precautions
Environmental precautions
Large spill
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
Small spill
3/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Exposure controls/personal protection
Europe
No exposure limit value known.
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor
or mist, use process enclosures, local exhaust ventilation or other engineering controls
to keep worker exposure to airborne contaminants below any recommended or statutory
limits.
Hygiene measures
Personal protection
Respiratory
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Hands
Eyes
Skin
4/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-AmpsTM 80
8.
Exposure controls/personal protection
Environmental exposure
controls
9.
Surfact-AmpsTM 80
11 . Toxicological information
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Physical and chemical properties
Physical state
Dispersibility properties
Solubility
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Possibility of hazardous
reactions
Result
LD50
Intraperitoneal
LD50
Intraperitoneal
LD50 Intravenous
LD50 Intravenous
LD50 Oral
TDLo Oral
: Not available.
Conclusion/Summary
Chronic toxicity
Product/ingredient name
Polyoxyethylenesorbitan Monooleate
Result
Chronic TD50
Oral
: Not available.
Species
Rat
Dose
6804 mg/kg
Exposure
-
Rat
6804 mg/kg
-
Rat
Rat
Rat
Rat
1790 mg/kg
1790 mg/kg
34500 uL/kg
20 mg/kg
-
Species
Rat
Dose
42 g/kg TDLo
Data
Exposure
2 weeks
Continuous
Dose
10 g/kg
Exposure
27 weeks
Intermittent
2163 g/kg
2 years
Continuous
Conclusion/Summary
Carcinogenicity
Product/ingredient name
Polyoxyethylenesorbitan Monooleate
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
Maternal
toxicity
-
Development
toxin
-
Species
Dose
-
Fertility
Rat
Oral:
635
g/kg
Exposure
Multigenerational
Positive
-
-
Rat Female
Intraperitoneal:
4D POST
-
-
-
Rat
80
uL/kg
Oral:
1270
g/kg
84D PRE21D POST
: Not available.
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
Other adverse effects
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: Not available.
: No known significant effects or critical hazards.
13 . Disposal considerations
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Hazardous waste
5/8
5/18/2010.
:
:
:
:
:
:
12 . Ecological information
Waste disposal
Result
Species
Rat
Equivocal Subcutaneous TDLo
Equivocal - Oral - Rat
TDLo
: Not available.
3747 N. Meridian Rd.
PO Box 117
Equivocal
Europe
United States
Acute toxicity
Product/ingredient name
Polyoxyethylenesorbitan Monooleate
Biosciences Division
Pierce
Polyoxyethylenesorbitan Monooleate
Conclusion/Summary
Result
Equivocal
: Not available.
: Will not occur.
11 . Toxicological information
Conclusion/Summary
Mutagenicity
Experiment
Mammalian-Human;
Somatic
Mammalian-Animal;
Somatic
: Not available.
Reproductive toxicity
Product/ingredient name
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
Test
DNA Inhibition
DNA Inhibition
Conclusion/Summary
Teratogenicity
Conclusion/Summary
: Liquid.
: Dispersible in the following materials: cold water and hot water.
: Soluble in the following materials: cold water and hot water.
10 . Stability and reactivity
Chemical stability
Product/ingredient name
Polyoxyethylenesorbitan Monooleate
6/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-AmpsTM 80
Surfact-AmpsTM 80
13 . Disposal considerations
16 . Other information
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Label requirements
Hazardous Material
Information System (U.S.A.)
14 . Transport information
Regulatory
information
UN number
Proper shipping
name
DOT Classification
Not
regulated.
-
IATA-DGR Class
Not available. Not available.
Classes
PG*
-
-
Not available.
-
: MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
:
Health
1
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
PG* : Packing group
15 . Regulatory information
United States
HCS Classification
U.S. Federal regulations
Canada inventory
EU regulations
1
0
Instability
Special
: Not regulated.
: United States inventory (TSCA 8b): All components are listed or exempted.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Polyoxyethylenesorbitan Monooleate
SARA 311/312 MSDS distribution - chemical inventory - hazard identification:
Polyoxyethylenesorbitan Monooleate: Immediate (acute) health hazard
Date of printing
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
Canada
WHMIS (Canada)
Canadian lists
Flammability
0
Health
: Not controlled under WHMIS (Canada).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: 5/18/2010.
: 5/18/2010.
Date of issue
Date of previous issue
: 9/26/2008.
Version
: 1.01
Indicates information that has changed from previously issued version.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
: Canada inventory: All components are listed or exempted.
: This product is not classified according to EU legislation.
:
Risk phrases
International regulations
International lists
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): All components are listed or exempted.
7/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
8/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Part of Thermo Fisher Scientific
Triton X-114; Surfact-Amp X-114
2.
Material Safety Data Sheet
1.
Product and company identification
: Triton X-114; Surfact-Amp X-114
Manufacturer
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product name
Supplier
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
2.
:
:
:
:
:
:
0028332 0028332B 1885280
0945
6/4/2010.
6/4/2010.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
Emergency overview
Medical conditions
aggravated by overexposure
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
: Liquid.
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
: WARNING !
CAUSES EYE IRRITATION. MAY CAUSE RESPIRATORY TRACT AND SKIN
IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
Severely irritating to eyes. Slightly irritating to the skin and respiratory system. Avoid
exposure - obtain special instructions before use. Do not breathe vapor or mist. Do not
get in eyes. Avoid contact with skin and clothing. Contains material that can cause
target organ damage. Use only with adequate ventilation. Keep container tightly closed
and sealed until ready for use. Wash thoroughly after handling.
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
The preparation is classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Xi; R36
Human health hazards
: Irritating to eyes.
See toxicological information (section 11)
3.
Composition/information on ingredients
United States
Name
Polyethylene Glycol Octylphenyl Ether
Europe
Substance/preparation
Ingredient name
CAS number
9036-19-5
%
7 - 10
: Preparation
CAS
number
9036-19-5
%
EC number
Classification
[1]
Xi; R41,
R37/38
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
7 - 10
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
Occupational exposure limits, if available, are listed in section 8.
1/8
3747 N. Meridian Rd.
PO Box 117
: Pre-existing disorders involving any target organs mentioned in this MSDS as being at
risk may be aggravated by over-exposure to this product.
Polyethylene Glycol Octylphenyl Ether
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: Slightly irritating to the respiratory system.
: No known significant effects or critical hazards.
Ingestion
: Slightly irritating to the skin.
Skin
: Severely irritating to eyes. Risk of serious damage to eyes.
Eyes
Potential chronic health effects
Chronic effects
: Contains material that can cause target organ damage.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Biosciences Division
Pierce
: No specific data.
: Adverse symptoms may include the following:
irritation
redness
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Ingestion
Skin
Eyes
6/4/2010.
: No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: Contains material which causes damage to the following organs: upper respiratory tract,
skin, eyes.
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747
800.874.3723
Hazards identification
Physical state
OSHA/HCS status
Hazards identification
Developmental effects
Fertility effects
Target organs
2/8
6/4/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Triton X-114; Surfact-Amp X-114
Triton X-114; Surfact-Amp X-114
4.
6.
First aid measures
Inhalation
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. It may be dangerous to the person providing aid to give mouth-tomouth resuscitation. Get medical attention. If unconscious, place in recovery position
and get medical attention immediately. Maintain an open airway. Loosen tight clothing
such as a collar, tie, belt or waistband.
Ingestion
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention. Never give anything by mouth to an
unconscious person. If unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen tight clothing such as a collar,
tie, belt or waistband.
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Continue to rinse for at least 10 minutes. Get medical attention if symptoms
occur. Wash clothing before reuse. Clean shoes thoroughly before reuse.
Eye contact
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention. Chemical burns must be treated promptly by a physician.
Protection of first-aiders
: No action shall be taken involving any personal risk or without suitable training. It may
be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
See section 11 for more detailed information on health effects and symptoms.
Accidental release measures
Large spill
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Small spill
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
7.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store between the following temperatures: 20 to 25°C (68 to 77°F). Store in accordance
with local regulations. Store in original container protected from direct sunlight in a dry,
cool and well-ventilated area, away from incompatible materials (see section 10) and
food and drink. Keep container tightly closed and sealed until ready for use. Containers
that have been opened must be carefully resealed and kept upright to prevent leakage.
Do not store in unlabeled containers. Use appropriate containment to avoid
environmental contamination.
Skin contact
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Hazardous combustion
products
Special protective
equipment for fire-fighters
6.
: In a fire or if heated, a pressure increase will occur and the container may burst.
8.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: Decomposition products may include the following materials:
carbon oxides
Exposure controls/personal protection
Europe
No exposure limit value known.
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
Accidental release measures
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor
or mist, use process enclosures, local exhaust ventilation or other engineering controls
to keep worker exposure to airborne contaminants below any recommended or statutory
limits.
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Hygiene measures
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Personal protection
3/8
6/4/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
4/8
6/4/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Triton X-114; Surfact-Amp X-114
Triton X-114; Surfact-Amp X-114
8.
11 . Toxicological information
Exposure controls/personal protection
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Respiratory
Hands
:
Eyes
:
Skin
:
Environmental exposure
controls
:
9.
Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
10 . Stability and reactivity
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Possibility of hazardous
reactions
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
Result
LD50 Oral
LD50 Oral
LD50 Oral
LD50 Oral
: Not available.
Species
Rat
Dose
4 mL/kg
Exposure
-
Rat
Rat
Rat
3600 mg/kg
2800 mg/kg
4190 mg/kg
-
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: Not available.
: No known significant effects or critical hazards.
13 . Disposal considerations
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
DOT Classification
Not
regulated.
-
-
-
IATA-DGR Class
Not available. Not available.
Not available.
-
PG* : Packing group
5/8
3747 N. Meridian Rd.
PO Box 117
:
:
:
:
:
:
14 . Transport information
: Not available.
6/4/2010.
Biosciences Division
Pierce
: Not available.
Hazardous waste
: The classification of the product may meet the criteria for a hazardous waste.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
11 . Toxicological information
Conclusion/Summary
Chronic toxicity
Conclusion/Summary
Carcinogenicity
: Not available.
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
: Will not occur.
United States
Acute toxicity
Product/ingredient name
Poly(oxy-1,2-ethanediyl), .alpha.-[(1,1,3,3tetramethylbutyl)phenyl]-.omega.-hydroxy-
: Not available.
Europe
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
Other adverse effects
: Liquid.
: Slightly hazy and cloudy, colorless.
: Partially soluble in the following materials: cold water and hot water.
Chemical stability
: Not available.
12 . Ecological information
Physical and chemical properties
Physical state
Color
Solubility
Conclusion/Summary
Mutagenicity
Conclusion/Summary
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Conclusion/Summary
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
6/8
6/4/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Triton X-114; Surfact-Amp X-114
Triton X-114; Surfact-Amp X-114
15 . Regulatory information
15 . Regulatory information
United States
HCS Classification
International regulations
International lists
U.S. Federal regulations
: Irritating material
Target organ effects
: TSCA 8(a) PAIR: Poly(oxy-1,2-ethanediyl), .alpha.-[(1,1,3,3-tetramethylbutyl)phenyl].omega.-hydroxyUnited States inventory (TSCA 8b): All components are listed or exempted.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Poly(oxy-1,2-ethanediyl), .alpha.[(1,1,3,3-tetramethylbutyl)phenyl]-.omega.-hydroxySARA 311/312 MSDS distribution - chemical inventory - hazard identification:
Poly(oxy-1,2-ethanediyl), .alpha.-[(1,1,3,3-tetramethylbutyl)phenyl]-.omega.-hydroxy-:
Immediate (acute) health hazard, Delayed (chronic) health hazard
16 . Other information
Label requirements
Hazardous Material
Information System (U.S.A.)
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: ethylene oxide
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: ethylene oxide
California Prop. 65
WARNING: This product contains a chemical known to the State of California to cause cancer and birth defects or other
reproductive harm.
Maximum
Ingredient name
Cancer
Reproductive
No significant risk
acceptable dosage
level
level
1,4-Dioxacyclohexane
Yes.
No.
30 µg/day (ingestion) No.
30 µg/day (inhalation)
ethylene oxide
Yes.
Yes.
2 µg/day (ingestion) 20 µg/day (ingestion)
2 µg/day (inhalation) 20 µg/day (inhalation)
Canada
WHMIS (Canada)
Canadian lists
Canada inventory
EU regulations
: Class D-2B: Material causing other toxic effects (Toxic).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: The following components are listed: Octylphenol and its ethoxylates
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: CAUSES EYE IRRITATION. MAY CAUSE RESPIRATORY TRACT AND SKIN
IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.
:
Health
2
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
Flammability
0
Health
2
0
Instability
Special
Date of printing
: 6/4/2010.
: 6/4/2010.
Date of issue
Date of previous issue
: 5/18/2010.
Version
: 1.02
Indicates information that has changed from previously issued version.
: R41- Risk of serious damage to eyes.
Full text of R-phrases
R36- Irritating to eyes.
referred to in sections 2 and
R37/38- Irritating to respiratory system and skin.
3 - Europe
: Xi - Irritant
Full text of classifications
referred to in sections 2 and
3 - Europe
: Canada inventory: All components are listed or exempted.
Hazard symbol or symbols
:
Risk phrases
Irritant
: R36- Irritating to eyes.
:
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
7/8
6/4/2010.
Biosciences Division
Pierce
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): All components are listed or exempted.
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
8/8
6/4/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Part of Thermo Fisher Scientific
Surfact-Amps 58; Brij 58
2.
Material Safety Data Sheet
1.
Product and company identification
Product name
Supplier
: Surfact-Amps 58; Brij 58
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
Product No.
MSDS #
Validation date
Print date
Responsible name
In case of emergency
:
:
:
:
:
:
2.
0028336 1885260
1925
5/18/2010.
5/18/2010.
MSDS (Regulatory Affairs)
CHEMTREC: Use of
800.424.9300 Substance/Preparation
OUTSIDE US:
202.483.7616
Medical conditions
aggravated by overexposure
3.
Emergency overview
: MAY CAUSE RESPIRATORY TRACT AND EYE IRRITATION.
Slightly irritating to the eyes and respiratory system. Avoid breathing vapor or mist.
Avoid contact with eyes. Use only with adequate ventilation. Keep container tightly
closed and sealed until ready for use. Wash thoroughly after handling.
4.
1/8
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
CAS number
9004-95-9
%
7 - 10
Substance/preparation
: Preparation
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Inhalation
: Slightly irritating to the respiratory system.
: No known significant effects or critical hazards.
Ingestion
: No known significant effects or critical hazards.
Skin
: Slightly irritating to the eyes.
Eyes
Potential chronic health effects
Chronic effects
: No known significant effects or critical hazards.
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Developmental effects
: No known significant effects or critical hazards.
Fertility effects
: No known significant effects or critical hazards.
5/18/2010.
Composition/information on ingredients
United States
Name
Surfact-Amps 58; Brij 58
Hazards identification
: Liquid.
: While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
: None known.
The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments.
Classification
: Not classified.
See toxicological information (section 11)
: Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
Physical state
OSHA/HCS status
: No specific data.
: No specific data.
: Adverse symptoms may include the following:
irritation
watering
redness
Ingestion
Skin
Eyes
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747
800.874.3723
Manufacturer
Hazards identification
Over-exposure signs/symptoms
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
First aid measures
Inhalation
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
by trained personnel. It may be dangerous to the person providing aid to give mouth-tomouth resuscitation. Get medical attention if adverse health effects persist or are
severe. If unconscious, place in recovery position and get medical attention
immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or
waistband.
Ingestion
: Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention if adverse health effects persist or are
severe. Never give anything by mouth to an unconscious person. If unconscious, place
in recovery position and get medical attention immediately. Maintain an open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.
Skin contact
: Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean
shoes thoroughly before reuse.
2/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps 58; Brij 58
4.
Surfact-Amps 58; Brij 58
First aid measures
Eye contact
Protection of first-aiders
7.
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention if irritation occurs.
: No action shall be taken involving any personal risk or without suitable training. It may
be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
Handling and storage
Handling
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin and clothing.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Storage
: Store between the following temperatures: 20 to 25°C (68 to 77°F). Store in accordance
with local regulations. Store in original container protected from direct sunlight in a dry,
cool and well-ventilated area, away from incompatible materials (see section 10) and
food and drink. Keep container tightly closed and sealed until ready for use. Containers
that have been opened must be carefully resealed and kept upright to prevent leakage.
Do not store in unlabeled containers. Use appropriate containment to avoid
environmental contamination.
See section 11 for more detailed information on health effects and symptoms.
5.
Fire-fighting measures
Flammability of the product
Extinguishing media
Suitable
Not suitable
Special exposure hazards
Hazardous combustion
products
Special protective
equipment for fire-fighters
6.
: In a fire or if heated, a pressure increase will occur and the container may burst.
: Use an extinguishing agent suitable for the surrounding fire.
: None known.
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training.
: Decomposition products may include the following materials:
carbon oxides
8.
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
Accidental release measures
Personal precautions
: No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
Large spill
: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
Small spill
Exposure controls/personal protection
Europe
No exposure limit value known.
Consult local authorities for acceptable exposure limits.
Recommended monitoring
: If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor
or mist, use process enclosures, local exhaust ventilation or other engineering controls
to keep worker exposure to airborne contaminants below any recommended or statutory
limits.
Hygiene measures
Personal protection
Respiratory
3/8
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
: Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Hands
Eyes
Skin
5/18/2010.
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
4/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps 58; Brij 58
8.
Exposure controls/personal protection
Environmental exposure
controls
9.
Surfact-Amps 58; Brij 58
11 . Toxicological information
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
Physical and chemical properties
Physical state
Color
Relative density
Solubility
:
:
:
:
Liquid.
Clear Colorless.
1.06
Partially soluble in the following materials: cold water and hot water.
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Possibility of hazardous
reactions
: The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
: No specific data.
: No specific data.
: Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
11 . Toxicological information
Result
LD50 Oral
LD50 Oral
Conclusion/Summary
: Not available.
Chronic toxicity
Conclusion/Summary
: Not available.
Carcinogenicity
Conclusion/Summary
: Not available.
Classification
Product/ingredient name
ACGIH
IARC
Poly(oxy-1,2-ethanediyl), .alpha.hexadecyl-.omega.-hydroxyMutagenicity
Conclusion/Summary
: Not available.
Teratogenicity
Conclusion/Summary
Reproductive toxicity
Conclusion/Summary
Environmental effects
United States
Aquatic ecotoxicity
Conclusion/Summary
Other adverse effects
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
: No known significant effects or critical hazards.
: Not available.
: No known significant effects or critical hazards.
13 . Disposal considerations
Waste disposal
: The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Hazardous waste
: Within the present knowledge of the supplier, this product is not regarded as
hazardous waste, as defined by EU Directive 91/689/EEC.
: Will not occur.
United States
Acute toxicity
Product/ingredient name
Poly(oxy-1,2-ethanediyl), .alpha.hexadecyl-.omega.-hydroxy-
:
:
:
:
:
:
12 . Ecological information
10 . Stability and reactivity
Chemical stability
Chronic effects
Carcinogenicity
Mutagenicity
Teratogenicity
Developmental effects
Fertility effects
Species
Mouse
Dose
2602 mg/kg
Exposure
-
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Rat
2500 mg/kg
-
14 . Transport information
EPA
-
NIOSH
None.
NTP
-
OSHA
None.
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
DOT Classification
Not
regulated.
-
-
-
IATA-DGR Class
Not
regulated.
-
-
-
PG* : Packing group
15 . Regulatory information
United States
HCS Classification
U.S. Federal regulations
: Not available.
: Not regulated.
: United States inventory (TSCA 8b): All components are listed or exempted.
: Not available.
Europe
5/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
6/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
Surfact-Amps 58; Brij 58
Surfact-Amps 58; Brij 58
15 . Regulatory information
16 . Other information
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
Flammability
0
Health
1
0
Instability
Special
Date of printing
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
Canada
WHMIS (Canada)
Canadian lists
Canada inventory
EU regulations
: Not controlled under WHMIS (Canada).
: CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
: 5/18/2010.
: 5/18/2010.
Date of issue
Date of previous issue
: 6/9/2009.
Version
: 1.01
Indicates information that has changed from previously issued version.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
: Canada inventory: All components are listed or exempted.
: This product is not classified according to EU legislation.
:
Risk phrases
International regulations
International lists
: Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Korea inventory (KECI): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Japan inventory (ENCS): All components are listed or exempted.
16 . Other information
Label requirements
Hazardous Material
Information System (U.S.A.)
: MAY CAUSE RESPIRATORY TRACT AND EYE IRRITATION.
:
Health
1
Flammability
0
Physical hazards
0
The customer is responsible for determining the PPE code for this material.
:
National Fire Protection
Association (U.S.A.)
7/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce
8/8
5/18/2010.
Biosciences Division
Pierce
3747 N. Meridian Rd.
PO Box 117
Rockford, IL
61105
(815) 968-0747
(815) 968-7316 Fax
www.thermo.com/pierce